1LX5B

Crystal structure of the bmp7/actrii extracellular domain complex
Total Genus 20
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
94
structure length
94
Chain Sequence
ETQECLFFNANWERDRTNQTGVEPCYGDKDKRRHCFATWKNISGSIEIVKQGCWLDDINCYDRTDCIEKKDSPEVYFCCCEGNMCNEKFSYFPE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title The BMP7/ActRII Extracellular Domain Complex Provides New Insights into the Cooperative Nature of Receptor Assembly
pubmed doi rcsb
molecule tags Growth factor/growth factor receptor
source organism Homo sapiens
molecule keywords bone morphogenetic protein 7
total genus 20
structure length 94
sequence length 94
ec nomenclature ec 2.7.11.30: Receptor protein serine/threonine kinase.
pdb deposition date 2002-06-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 1lx5B00
2UX2A 3BT1U 1CDRA 2BTXA 1CCQA 2HLQA 2H64B 3U73U 1RL5A 4IYEA 1HC9A 4HQPF 1KTZB 1CHVS 3BT2U 2BHIA 5DZ5A 2ERAA 1KBSA 2UWRA 1FASA 1IK8A 1NXBA 1KL8A 1F94A 1QKEA 1LSIA 2LCRA 2PJYC 2H62C 2GOOC 1F8UB 1DRSA 4UY2C 1CB9A 2CDXA 3HH7A 5IMTD 1BTEA 4BIKB 3U74U 1I02A 2PJYB 2GOOB 4FAOE 2H7ZA 3ERAA 1CDSA 1TFSA 2QC1A 1FRAA 1COEA 1UG4A 2MJ0A 1LX5B 1IDHA 4ZQYA 2H5FA 1PLOA 1FSCA 1IQ9A 1HC9B 1IDGA 1XT3A 1FSSB 1REWC 2JQPA 5DU1A 1CVOA 1CREA 1NTNA 1NTXA 1CDTA 2MHYA 2CTXA 4XJJA 2CCXA 1CODA 2QJ9C 4OM5A 2LA1A 2VLWA 1MAHF 2ABXA 1IDIA 3KFDI 1ERAA 1CXNA 2HLRA 3EVSC 2H8UA 3LAQU 1HAJA 2NBTA 1TGXA 1CTXA 2H7ZB 1L4WA 5EBXA 4AEAA 1KXIA 1YWHA 4P7UA 4FAOC 5IMYC 2MUPA 1KS6A 2J8BA 1M9ZA 1NEAA 2OFSA 2H64C 2QJBC 1QKDA 1TXAA 1BXPA 1W6BA 2MUOA 2MFAA 1NYSA 1KU6B 1ONJA 2JVEA 1LJZA 2FD6U 3NH7A 1CXOA 2MJYA 3EBXA 2I9BE 1KBTA 1HOYA 1HAAA 4OM4A 1IJCA 4DO8A 1KBAA 1ABTA 3VTSA 1FFJA 2K3GA 1IDLA 2L03A 3QB4B 1FF4A 1QM7A 2N99A 3PLCA 1JE9A 5DO6A 1CDQA 2QJAC 1NORA 1VB0A 1B41B 2H62D 2X8BB 3NEQA 1LXGA 1KFHA 4LFTA 6EBXA 1S4YA 3NDSA 1NYUA 4QTIU 2L5SA 1JGKA 1V6PA 1ERGA 1ZADA 1LXHA 1CRFA 1KC4A 1ES7B 4EY8B 1RGJA 2MJ4A 1MR6A 1H0JA 2CRTA 4BDTB 1IKCA 1JBDA 3FEVA 3KFDE 2CRSA 4RUDA 1G6MA 1TXBA
chains in the Genus database with same CATH superfamily
2UX2A 3BT1U 1CDRA 2BTXA 1CCQA 2HLQA 2H64B 3U73U 1RL5A 4IYEA 1HC9A 4HQPF 1KTZB 1CHVS 3BT2U 2BHIA 5DZ5A 2ERAA 1KBSA 2UWRA 1FASA 1IK8A 1NXBA 1KL8A 1F94A 1QKEA 1LSIA 2LCRA 2PJYC 2H62C 2GOOC 1F8UB 1DRSA 4UY2C 1CB9A 2CDXA 3HH7A 5IMTD 1BTEA 4BIKB 3U74U 1I02A 2PJYB 2GOOB 4FAOE 2H7ZA 3ERAA 1CDSA 1TFSA 2QC1A 1FRAA 1COEA 1UG4A 2MJ0A 1LX5B 1IDHA 4ZQYA 2H5FA 1PLOA 1FSCA 1IQ9A 1HC9B 1IDGA 1XT3A 1FSSB 1REWC 2JQPA 5DU1A 1CVOA 1CREA 1NTNA 1NTXA 1CDTA 2MHYA 2CTXA 4XJJA 2CCXA 1CODA 2QJ9C 4OM5A 2LA1A 2VLWA 1MAHF 2ABXA 1IDIA 3KFDI 1ERAA 1CXNA 2HLRA 3EVSC 2H8UA 3LAQU 1HAJA 2NBTA 1TGXA 1CTXA 2H7ZB 1L4WA 5EBXA 4AEAA 1KXIA 1YWHA 4P7UA 4FAOC 5IMYC 2MUPA 1KS6A 2J8BA 1M9ZA 1NEAA 2OFSA 2H64C 2QJBC 1QKDA 1TXAA 1BXPA 1W6BA 2MUOA 2MFAA 1NYSA 1KU6B 1ONJA 2JVEA 1LJZA 2FD6U 3NH7A 1CXOA 2MJYA 3EBXA 2I9BE 1KBTA 1HOYA 1HAAA 4OM4A 1IJCA 4DO8A 1KBAA 1ABTA 3VTSA 1FFJA 2K3GA 1IDLA 2L03A 3QB4B 1FF4A 1QM7A 2N99A 3PLCA 1JE9A 5DO6A 1CDQA 2QJAC 1NORA 1VB0A 1B41B 2H62D 2X8BB 3NEQA 1LXGA 1KFHA 4KSNA 4LFTA 6EBXA 1S4YA 3NDSA 1NYUA 4QTIU 2L5SA 1JGKA 1V6PA 1ERGA 1ZADA 1LXHA 1CRFA 1KC4A 1ES7B 4EY8B 1RGJA 2MJ4A 1MR6A 1H0JA 2CRTA 4BDTB 1IKCA 1JBDA 3FEVA 3KFDE 2CRSA 4RUDA 1G6MA 1TXBA
chains in the Genus database with same CATH topology
2UX2A 3BT1U 1CDRA 2BTXA 1CCQA 2HLQA 2H64B 3U73U 1RL5A 4IYEA 1HC9A 4HQPF 1KTZB 1CHVS 3BT2U 2BHIA 5DZ5A 2ERAA 1KBSA 2UWRA 1FASA 1IK8A 1NXBA 1KL8A 1F94A 1QKEA 1LSIA 2LCRA 2PJYC 2H62C 2GOOC 1F8UB 1DRSA 4UY2C 1CB9A 2CDXA 3HH7A 5IMTD 1BTEA 4BIKB 3U74U 1I02A 2PJYB 2GOOB 4FAOE 2H7ZA 3ERAA 1CDSA 1TFSA 2QC1A 1FRAA 1COEA 1UG4A 2MJ0A 1LX5B 1IDHA 4ZQYA 2H5FA 1PLOA 1FSCA 1IQ9A 1HC9B 1IDGA 1XT3A 1FSSB 1REWC 2JQPA 5DU1A 1CVOA 1CREA 1NTNA 1NTXA 1CDTA 2MHYA 2CTXA 4XJJA 2CCXA 1CODA 2QJ9C 4OM5A 2LA1A 2VLWA 1MAHF 2ABXA 1IDIA 3KFDI 1ERAA 1CXNA 2HLRA 3EVSC 2H8UA 3LAQU 1HAJA 2NBTA 1TGXA 1CTXA 2H7ZB 1L4WA 5EBXA 4AEAA 1KXIA 1YWHA 4P7UA 4FAOC 5IMYC 2MUPA 1KS6A 2J8BA 1M9ZA 1NEAA 2OFSA 2H64C 2QJBC 1QKDA 1TXAA 1BXPA 1W6BA 2MUOA 2MFAA 1NYSA 1KU6B 1ONJA 2JVEA 1LJZA 2FD6U 3NH7A 1CXOA 2MJYA 3EBXA 2I9BE 1KBTA 1HOYA 1HAAA 4OM4A 1IJCA 4DO8A 1KBAA 1ABTA 3VTSA 1FFJA 2K3GA 1IDLA 2L03A 3QB4B 1FF4A 1QM7A 2N99A 3PLCA 1JE9A 5DO6A 1CDQA 2QJAC 1NORA 1VB0A 1B41B 2H62D 2X8BB 3NEQA 1LXGA 1KFHA 4KSNA 4LFTA 6EBXA 1S4YA 3NDSA 1NYUA 4QTIU 2L5SA 1JGKA 1V6PA 1ERGA 1ZADA 1LXHA 1CRFA 1KC4A 1ES7B 4EY8B 1RGJA 2MJ4A 1MR6A 1H0JA 2CRTA 4BDTB 1IKCA 1JBDA 3FEVA 3KFDE 2CRSA 4RUDA 1G6MA 1TXBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2UX2 A;  3BT1 U;  1CDR A;  2BTX A;  1CCQ A;  2HLQ A;  2H64 B;  3U73 U;  1RL5 A;  4IYE A;  1HC9 A;  4HQP F;  1KTZ B;  1CHV S;  3BT2 U;  2BHI A;  5DZ5 A;  2ERA A;  1KBS A;  2UWR A;  1FAS A;  1IK8 A;  1NXB A;  1KL8 A;  1F94 A;  1QKE A;  1LSI A;  2LCR A;  2PJY C;  2H62 C;  2GOO C;  1F8U B;  1DRS A;  4UY2 C;  1CB9 A;  2CDX A;  3HH7 A;  5IMT D;  1BTE A;  4BIK B;  3U74 U;  1I02 A;  2PJY B;  2GOO B;  4FAO E;  2H7Z A;  3ERA A;  1CDS A;  1TFS A;  2QC1 A;  1FRA A;  1COE A;  1UG4 A;  2MJ0 A;  1LX5 B;  1IDH A;  4ZQY A;  2H5F A;  1PLO A;  1FSC A;  1IQ9 A;  1HC9 B;  1IDG A;  1XT3 A;  1FSS B;  1REW C;  2JQP A;  5DU1 A;  1CVO A;  1CRE A;  1NTN A;  1NTX A;  1CDT A;  2MHY A;  2CTX A;  4XJJ A;  2CCX A;  1COD A;  2QJ9 C;  4OM5 A;  2LA1 A;  2VLW A;  1MAH F;  2ABX A;  1IDI A;  3KFD I;  1ERA A;  1CXN A;  2HLR A;  3EVS C;  2H8U A;  3LAQ U;  1HAJ A;  2NBT A;  1TGX A;  1CTX A;  2H7Z B;  1L4W A;  5EBX A;  4AEA A;  1KXI A;  1YWH A;  4P7U A;  4FAO C;  5IMY C;  2MUP A;  1KS6 A;  2J8B A;  1M9Z A;  1NEA A;  2OFS A;  2H64 C;  2QJB C;  1QKD A;  1TXA A;  1BXP A;  1W6B A;  2MUO A;  2MFA A;  1NYS A;  1KU6 B;  1ONJ A;  2JVE A;  1LJZ A;  2FD6 U;  3NH7 A;  1CXO A;  2MJY A;  3EBX A;  2I9B E;  1KBT A;  1HOY A;  1HAA A;  4OM4 A;  1IJC A;  4DO8 A;  1KBA A;  1ABT A;  3VTS A;  1FFJ A;  2K3G A;  1IDL A;  2L03 A;  3QB4 B;  1FF4 A;  1QM7 A;  2N99 A;  3PLC A;  1JE9 A;  5DO6 A;  1CDQ A;  2QJA C;  1NOR A;  1VB0 A;  1B41 B;  2H62 D;  2X8B B;  3NEQ A;  1LXG A;  1KFH A;  4LFT A;  6EBX A;  1S4Y A;  3NDS A;  1NYU A;  4QTI U;  2L5S A;  1JGK A;  1V6P A;  1ERG A;  1ZAD A;  1LXH A;  1CRF A;  1KC4 A;  1ES7 B;  4EY8 B;  1RGJ A;  2MJ4 A;  1MR6 A;  1H0J A;  2CRT A;  4BDT B;  1IKC A;  1JBD A;  3FEV A;  3KFD E;  2CRS A;  4RUD A;  1G6M A;  1TXB A; 
#chains in the Genus database with same CATH topology
 2UX2 A;  3BT1 U;  1CDR A;  2BTX A;  1CCQ A;  2HLQ A;  2H64 B;  3U73 U;  1RL5 A;  4IYE A;  1HC9 A;  4HQP F;  1KTZ B;  1CHV S;  3BT2 U;  2BHI A;  5DZ5 A;  2ERA A;  1KBS A;  2UWR A;  1FAS A;  1IK8 A;  1NXB A;  1KL8 A;  1F94 A;  1QKE A;  1LSI A;  2LCR A;  2PJY C;  2H62 C;  2GOO C;  1F8U B;  1DRS A;  4UY2 C;  1CB9 A;  2CDX A;  3HH7 A;  5IMT D;  1BTE A;  4BIK B;  3U74 U;  1I02 A;  2PJY B;  2GOO B;  4FAO E;  2H7Z A;  3ERA A;  1CDS A;  1TFS A;  2QC1 A;  1FRA A;  1COE A;  1UG4 A;  2MJ0 A;  1LX5 B;  1IDH A;  4ZQY A;  2H5F A;  1PLO A;  1FSC A;  1IQ9 A;  1HC9 B;  1IDG A;  1XT3 A;  1FSS B;  1REW C;  2JQP A;  5DU1 A;  1CVO A;  1CRE A;  1NTN A;  1NTX A;  1CDT A;  2MHY A;  2CTX A;  4XJJ A;  2CCX A;  1COD A;  2QJ9 C;  4OM5 A;  2LA1 A;  2VLW A;  1MAH F;  2ABX A;  1IDI A;  3KFD I;  1ERA A;  1CXN A;  2HLR A;  3EVS C;  2H8U A;  3LAQ U;  1HAJ A;  2NBT A;  1TGX A;  1CTX A;  2H7Z B;  1L4W A;  5EBX A;  4AEA A;  1KXI A;  1YWH A;  4P7U A;  4FAO C;  5IMY C;  2MUP A;  1KS6 A;  2J8B A;  1M9Z A;  1NEA A;  2OFS A;  2H64 C;  2QJB C;  1QKD A;  1TXA A;  1BXP A;  1W6B A;  2MUO A;  2MFA A;  1NYS A;  1KU6 B;  1ONJ A;  2JVE A;  1LJZ A;  2FD6 U;  3NH7 A;  1CXO A;  2MJY A;  3EBX A;  2I9B E;  1KBT A;  1HOY A;  1HAA A;  4OM4 A;  1IJC A;  4DO8 A;  1KBA A;  1ABT A;  3VTS A;  1FFJ A;  2K3G A;  1IDL A;  2L03 A;  3QB4 B;  1FF4 A;  1QM7 A;  2N99 A;  3PLC A;  1JE9 A;  5DO6 A;  1CDQ A;  2QJA C;  1NOR A;  1VB0 A;  1B41 B;  2H62 D;  2X8B B;  3NEQ A;  1LXG A;  1KFH A;  4KSN A;  4LFT A;  6EBX A;  1S4Y A;  3NDS A;  1NYU A;  4QTI U;  2L5S A;  1JGK A;  1V6P A;  1ERG A;  1ZAD A;  1LXH A;  1CRF A;  1KC4 A;  1ES7 B;  4EY8 B;  1RGJ A;  2MJ4 A;  1MR6 A;  1H0J A;  2CRT A;  4BDT B;  1IKC A;  1JBD A;  3FEV A;  3KFD E;  2CRS A;  4RUD A;  1G6M A;  1TXB A; 
#chains in the Genus database with same CATH homology
 2UX2 A;  3BT1 U;  1CDR A;  2BTX A;  1CCQ A;  2HLQ A;  2H64 B;  3U73 U;  1RL5 A;  4IYE A;  1HC9 A;  4HQP F;  1KTZ B;  1CHV S;  3BT2 U;  2BHI A;  5DZ5 A;  2ERA A;  1KBS A;  2UWR A;  1FAS A;  1IK8 A;  1NXB A;  1KL8 A;  1F94 A;  1QKE A;  1LSI A;  2LCR A;  2PJY C;  2H62 C;  2GOO C;  1F8U B;  1DRS A;  4UY2 C;  1CB9 A;  2CDX A;  3HH7 A;  5IMT D;  1BTE A;  4BIK B;  3U74 U;  1I02 A;  2PJY B;  2GOO B;  4FAO E;  2H7Z A;  3ERA A;  1CDS A;  1TFS A;  2QC1 A;  1FRA A;  1COE A;  1UG4 A;  2MJ0 A;  1LX5 B;  1IDH A;  4ZQY A;  2H5F A;  1PLO A;  1FSC A;  1IQ9 A;  1HC9 B;  1IDG A;  1XT3 A;  1FSS B;  1REW C;  2JQP A;  5DU1 A;  1CVO A;  1CRE A;  1NTN A;  1NTX A;  1CDT A;  2MHY A;  2CTX A;  4XJJ A;  2CCX A;  1COD A;  2QJ9 C;  4OM5 A;  2LA1 A;  2VLW A;  1MAH F;  2ABX A;  1IDI A;  3KFD I;  1ERA A;  1CXN A;  2HLR A;  3EVS C;  2H8U A;  3LAQ U;  1HAJ A;  2NBT A;  1TGX A;  1CTX A;  2H7Z B;  1L4W A;  5EBX A;  4AEA A;  1KXI A;  1YWH A;  4P7U A;  4FAO C;  5IMY C;  2MUP A;  1KS6 A;  2J8B A;  1M9Z A;  1NEA A;  2OFS A;  2H64 C;  2QJB C;  1QKD A;  1TXA A;  1BXP A;  1W6B A;  2MUO A;  2MFA A;  1NYS A;  1KU6 B;  1ONJ A;  2JVE A;  1LJZ A;  2FD6 U;  3NH7 A;  1CXO A;  2MJY A;  3EBX A;  2I9B E;  1KBT A;  1HOY A;  1HAA A;  4OM4 A;  1IJC A;  4DO8 A;  1KBA A;  1ABT A;  3VTS A;  1FFJ A;  2K3G A;  1IDL A;  2L03 A;  3QB4 B;  1FF4 A;  1QM7 A;  2N99 A;  3PLC A;  1JE9 A;  5DO6 A;  1CDQ A;  2QJA C;  1NOR A;  1VB0 A;  1B41 B;  2H62 D;  2X8B B;  3NEQ A;  1LXG A;  1KFH A;  4KSN A;  4LFT A;  6EBX A;  1S4Y A;  3NDS A;  1NYU A;  4QTI U;  2L5S A;  1JGK A;  1V6P A;  1ERG A;  1ZAD A;  1LXH A;  1CRF A;  1KC4 A;  1ES7 B;  4EY8 B;  1RGJ A;  2MJ4 A;  1MR6 A;  1H0J A;  2CRT A;  4BDT B;  1IKC A;  1JBD A;  3FEV A;  3KFD E;  2CRS A;  4RUD A;  1G6M A;  1TXB A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...