1LXGA

Solution structure of alpha-cobratoxin complexed with a cognate peptide (structure ensemble)
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
71
structure length
71
Chain Sequence
IRCFITPDITSKDCPNGHVCYTKTWCDAFCSIRGKRVDLGCAATCPTVKTGVDIQCCSTDNCNPFPTRKRP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title NMR-based Binding Screen and Structural Analysis of the Complex Formed between alpha-Cobratoxin and an 18-mer Cognate Peptide Derived from the alpha1 Subunit of the Nicotinic Acetylcholine Receptor from Torpedo californica
pubmed doi rcsb
molecule tags Toxin
source organism Torpedo californica
molecule keywords Long neurotoxin 1
total genus 4
structure length 71
sequence length 71
ec nomenclature
pdb deposition date 2002-06-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00087 Toxin_TOLIP Snake toxin and toxin-like protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 1lxgA00
2MUPA 2BHIA 1ERAA 2FD6U 1KS6A 2MJYA 2QC1A 1HAJA 4OM5A 2PJYC 4FAOE 2N99A 1DRSA 2H62D 1ES7B 1TXBA 1JE9A 4LFTA 2CRTA 3U73U 1G6MA 1KC4A 1RGJA 1ONJA 2CDXA 1BTEA 1FSCA 2MJ0A 2LCRA 5DO6A 2ERAA 1IDGA 1S4YA 5IMYC 1YWHA 3QB4B 1CXOA 1QKDA 1NTNA 2H64B 2CRSA 2H5FA 1W6BA 2OFSA 2MUOA 1HC9B 2QJBC 6EBXA 3BT1U 4BDTB 2UWRA 3NEQA 3BT2U 3LAQU 4OM4A 2QJAC 1KBAA 1IKCA 2LA1A 1IDLA 1UG4A 1ZADA 1L4WA 4ZQYA 1F94A 1M9ZA 1IK8A 1CTXA 1XT3A 2MFAA 1JGKA 1NXBA 3EVSC 5IMTD 2GOOC 1LSIA 1LXHA 1CXNA 1KBTA 1FFJA 1FSSB 1IJCA 2H62C 1BXPA 1HC9A 1NORA 1FASA 3KFDI 2HLQA 1KXIA 4AEAA 2H8UA 1ERGA 4DO8A 1F8UB 3EBXA 1CDTA 2H7ZB 4RUDA 1H0JA 2X8BB 2BTXA 1CHVS 4HQPF 1LX5B 3U74U 1NEAA 1CDSA 2K3GA 1FF4A 1B41B 3ERAA 1CDQA 1CB9A 1RL5A 3VTSA 2J8BA 1KBSA 1VB0A 1CCQA 1JBDA 2I9BE 2PJYB 3PLCA 1TGXA 4IYEA 4P7UA 4UY2C 1NYUA 1MAHF 1REWC 1FRAA 5EBXA 5DU1A 3NH7A 2MJ4A 1HOYA 1NYSA 2GOOB 2ABXA 1TFSA 1NTXA 2H7ZA 1LJZA 1IDHA 1PLOA 1COEA 4FAOC 1KU6B 1LXGA 1CREA 2HLRA 1KL8A 4QTIU 1QM7A 2JQPA 1HAAA 4BIKB 1ABTA 1CDRA 1CVOA 2NBTA 2UX2A 1KTZB 1V6PA 1IDIA 3FEVA 2L5SA 2CTXA 1I02A 2H64C 1CODA 2L03A 2JVEA 1QKEA 4EY8B 1MR6A 2CCXA 1TXAA 5DZ5A 1KFHA 3NDSA 1CRFA 2QJ9C 1IQ9A 3HH7A 4XJJA 2VLWA 2MHYA 3KFDE
chains in the Genus database with same CATH superfamily
2MUPA 2BHIA 1ERAA 2FD6U 1KS6A 2MJYA 2QC1A 1HAJA 4OM5A 2PJYC 4FAOE 2N99A 1DRSA 2H62D 1ES7B 1TXBA 1JE9A 4LFTA 2CRTA 3U73U 1G6MA 1KC4A 1RGJA 1ONJA 2CDXA 1BTEA 1FSCA 2MJ0A 2LCRA 5DO6A 2ERAA 1IDGA 1S4YA 5IMYC 1YWHA 3QB4B 1CXOA 1QKDA 1NTNA 2H64B 2CRSA 2H5FA 1W6BA 2OFSA 2MUOA 1HC9B 2QJBC 6EBXA 3BT1U 4BDTB 2UWRA 3NEQA 3BT2U 3LAQU 4OM4A 2QJAC 1KBAA 1IKCA 2LA1A 1IDLA 1UG4A 1ZADA 1L4WA 4ZQYA 1F94A 1M9ZA 1IK8A 1CTXA 1XT3A 2MFAA 1JGKA 1NXBA 3EVSC 5IMTD 2GOOC 1LSIA 1LXHA 1CXNA 1KBTA 1FFJA 1FSSB 1IJCA 2H62C 1BXPA 1HC9A 1NORA 1FASA 3KFDI 2HLQA 1KXIA 4AEAA 2H8UA 1ERGA 4DO8A 1F8UB 3EBXA 1CDTA 2H7ZB 4RUDA 1H0JA 2X8BB 2BTXA 1CHVS 4HQPF 1LX5B 3U74U 1NEAA 1CDSA 2K3GA 1FF4A 1B41B 3ERAA 1CDQA 1CB9A 1RL5A 3VTSA 2J8BA 1KBSA 1VB0A 1CCQA 1JBDA 2I9BE 2PJYB 3PLCA 1TGXA 4IYEA 4P7UA 4UY2C 1NYUA 1MAHF 1REWC 4KSNA 1FRAA 5EBXA 5DU1A 3NH7A 2MJ4A 1HOYA 1NYSA 2GOOB 2ABXA 1TFSA 1NTXA 2H7ZA 1LJZA 1IDHA 1PLOA 1COEA 4FAOC 1KU6B 1LXGA 1CREA 2HLRA 1KL8A 4QTIU 1QM7A 2JQPA 1HAAA 4BIKB 1ABTA 1CDRA 1CVOA 2NBTA 2UX2A 1KTZB 1V6PA 1IDIA 3FEVA 2L5SA 2CTXA 1I02A 2H64C 1CODA 2L03A 2JVEA 1QKEA 4EY8B 1MR6A 2CCXA 1TXAA 5DZ5A 1KFHA 3NDSA 1CRFA 2QJ9C 1IQ9A 3HH7A 4XJJA 2VLWA 2MHYA 3KFDE
chains in the Genus database with same CATH topology
2MUPA 2BHIA 1ERAA 2FD6U 1KS6A 2MJYA 2QC1A 1HAJA 4OM5A 2PJYC 4FAOE 2N99A 1DRSA 2H62D 1ES7B 1TXBA 1JE9A 4LFTA 2CRTA 3U73U 1G6MA 1KC4A 1RGJA 1ONJA 2CDXA 1BTEA 1FSCA 2MJ0A 2LCRA 5DO6A 2ERAA 1IDGA 1S4YA 5IMYC 1YWHA 3QB4B 1CXOA 1QKDA 1NTNA 2H64B 2CRSA 2H5FA 1W6BA 2OFSA 2MUOA 1HC9B 2QJBC 6EBXA 3BT1U 4BDTB 2UWRA 3NEQA 3BT2U 3LAQU 4OM4A 2QJAC 1KBAA 1IKCA 2LA1A 1IDLA 1UG4A 1ZADA 1L4WA 4ZQYA 1F94A 1M9ZA 1IK8A 1CTXA 1XT3A 2MFAA 1JGKA 1NXBA 3EVSC 5IMTD 2GOOC 1LSIA 1LXHA 1CXNA 1KBTA 1FFJA 1FSSB 1IJCA 2H62C 1BXPA 1HC9A 1NORA 1FASA 3KFDI 2HLQA 1KXIA 4AEAA 2H8UA 1ERGA 4DO8A 1F8UB 3EBXA 1CDTA 2H7ZB 4RUDA 1H0JA 2X8BB 2BTXA 1CHVS 4HQPF 1LX5B 3U74U 1NEAA 1CDSA 2K3GA 1FF4A 1B41B 3ERAA 1CDQA 1CB9A 1RL5A 3VTSA 2J8BA 1KBSA 1VB0A 1CCQA 1JBDA 2I9BE 2PJYB 3PLCA 1TGXA 4IYEA 4P7UA 4UY2C 1NYUA 1MAHF 1REWC 4KSNA 1FRAA 5EBXA 5DU1A 3NH7A 2MJ4A 1HOYA 1NYSA 2GOOB 2ABXA 1TFSA 1NTXA 2H7ZA 1LJZA 1IDHA 1PLOA 1COEA 4FAOC 1KU6B 1LXGA 1CREA 2HLRA 1KL8A 4QTIU 1QM7A 2JQPA 1HAAA 4BIKB 1ABTA 1CDRA 1CVOA 2NBTA 2UX2A 1KTZB 1V6PA 1IDIA 3FEVA 2L5SA 2CTXA 1I02A 2H64C 1CODA 2L03A 2JVEA 1QKEA 4EY8B 1MR6A 2CCXA 1TXAA 5DZ5A 1KFHA 3NDSA 1CRFA 2QJ9C 1IQ9A 3HH7A 4XJJA 2VLWA 2MHYA 3KFDE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2MUP A;  2BHI A;  1ERA A;  2FD6 U;  1KS6 A;  2MJY A;  2QC1 A;  1HAJ A;  4OM5 A;  2PJY C;  4FAO E;  2N99 A;  1DRS A;  2H62 D;  1ES7 B;  1TXB A;  1JE9 A;  4LFT A;  2CRT A;  3U73 U;  1G6M A;  1KC4 A;  1RGJ A;  1ONJ A;  2CDX A;  1BTE A;  1FSC A;  2MJ0 A;  2LCR A;  5DO6 A;  2ERA A;  1IDG A;  1S4Y A;  5IMY C;  1YWH A;  3QB4 B;  1CXO A;  1QKD A;  1NTN A;  2H64 B;  2CRS A;  2H5F A;  1W6B A;  2OFS A;  2MUO A;  1HC9 B;  2QJB C;  6EBX A;  3BT1 U;  4BDT B;  2UWR A;  3NEQ A;  3BT2 U;  3LAQ U;  4OM4 A;  2QJA C;  1KBA A;  1IKC A;  2LA1 A;  1IDL A;  1UG4 A;  1ZAD A;  1L4W A;  4ZQY A;  1F94 A;  1M9Z A;  1IK8 A;  1CTX A;  1XT3 A;  2MFA A;  1JGK A;  1NXB A;  3EVS C;  5IMT D;  2GOO C;  1LSI A;  1LXH A;  1CXN A;  1KBT A;  1FFJ A;  1FSS B;  1IJC A;  2H62 C;  1BXP A;  1HC9 A;  1NOR A;  1FAS A;  3KFD I;  2HLQ A;  1KXI A;  4AEA A;  2H8U A;  1ERG A;  4DO8 A;  1F8U B;  3EBX A;  1CDT A;  2H7Z B;  4RUD A;  1H0J A;  2X8B B;  2BTX A;  1CHV S;  4HQP F;  1LX5 B;  3U74 U;  1NEA A;  1CDS A;  2K3G A;  1FF4 A;  1B41 B;  3ERA A;  1CDQ A;  1CB9 A;  1RL5 A;  3VTS A;  2J8B A;  1KBS A;  1VB0 A;  1CCQ A;  1JBD A;  2I9B E;  2PJY B;  3PLC A;  1TGX A;  4IYE A;  4P7U A;  4UY2 C;  1NYU A;  1MAH F;  1REW C;  1FRA A;  5EBX A;  5DU1 A;  3NH7 A;  2MJ4 A;  1HOY A;  1NYS A;  2GOO B;  2ABX A;  1TFS A;  1NTX A;  2H7Z A;  1LJZ A;  1IDH A;  1PLO A;  1COE A;  4FAO C;  1KU6 B;  1LXG A;  1CRE A;  2HLR A;  1KL8 A;  4QTI U;  1QM7 A;  2JQP A;  1HAA A;  4BIK B;  1ABT A;  1CDR A;  1CVO A;  2NBT A;  2UX2 A;  1KTZ B;  1V6P A;  1IDI A;  3FEV A;  2L5S A;  2CTX A;  1I02 A;  2H64 C;  1COD A;  2L03 A;  2JVE A;  1QKE A;  4EY8 B;  1MR6 A;  2CCX A;  1TXA A;  5DZ5 A;  1KFH A;  3NDS A;  1CRF A;  2QJ9 C;  1IQ9 A;  3HH7 A;  4XJJ A;  2VLW A;  2MHY A;  3KFD E; 
#chains in the Genus database with same CATH topology
 2MUP A;  2BHI A;  1ERA A;  2FD6 U;  1KS6 A;  2MJY A;  2QC1 A;  1HAJ A;  4OM5 A;  2PJY C;  4FAO E;  2N99 A;  1DRS A;  2H62 D;  1ES7 B;  1TXB A;  1JE9 A;  4LFT A;  2CRT A;  3U73 U;  1G6M A;  1KC4 A;  1RGJ A;  1ONJ A;  2CDX A;  1BTE A;  1FSC A;  2MJ0 A;  2LCR A;  5DO6 A;  2ERA A;  1IDG A;  1S4Y A;  5IMY C;  1YWH A;  3QB4 B;  1CXO A;  1QKD A;  1NTN A;  2H64 B;  2CRS A;  2H5F A;  1W6B A;  2OFS A;  2MUO A;  1HC9 B;  2QJB C;  6EBX A;  3BT1 U;  4BDT B;  2UWR A;  3NEQ A;  3BT2 U;  3LAQ U;  4OM4 A;  2QJA C;  1KBA A;  1IKC A;  2LA1 A;  1IDL A;  1UG4 A;  1ZAD A;  1L4W A;  4ZQY A;  1F94 A;  1M9Z A;  1IK8 A;  1CTX A;  1XT3 A;  2MFA A;  1JGK A;  1NXB A;  3EVS C;  5IMT D;  2GOO C;  1LSI A;  1LXH A;  1CXN A;  1KBT A;  1FFJ A;  1FSS B;  1IJC A;  2H62 C;  1BXP A;  1HC9 A;  1NOR A;  1FAS A;  3KFD I;  2HLQ A;  1KXI A;  4AEA A;  2H8U A;  1ERG A;  4DO8 A;  1F8U B;  3EBX A;  1CDT A;  2H7Z B;  4RUD A;  1H0J A;  2X8B B;  2BTX A;  1CHV S;  4HQP F;  1LX5 B;  3U74 U;  1NEA A;  1CDS A;  2K3G A;  1FF4 A;  1B41 B;  3ERA A;  1CDQ A;  1CB9 A;  1RL5 A;  3VTS A;  2J8B A;  1KBS A;  1VB0 A;  1CCQ A;  1JBD A;  2I9B E;  2PJY B;  3PLC A;  1TGX A;  4IYE A;  4P7U A;  4UY2 C;  1NYU A;  1MAH F;  1REW C;  4KSN A;  1FRA A;  5EBX A;  5DU1 A;  3NH7 A;  2MJ4 A;  1HOY A;  1NYS A;  2GOO B;  2ABX A;  1TFS A;  1NTX A;  2H7Z A;  1LJZ A;  1IDH A;  1PLO A;  1COE A;  4FAO C;  1KU6 B;  1LXG A;  1CRE A;  2HLR A;  1KL8 A;  4QTI U;  1QM7 A;  2JQP A;  1HAA A;  4BIK B;  1ABT A;  1CDR A;  1CVO A;  2NBT A;  2UX2 A;  1KTZ B;  1V6P A;  1IDI A;  3FEV A;  2L5S A;  2CTX A;  1I02 A;  2H64 C;  1COD A;  2L03 A;  2JVE A;  1QKE A;  4EY8 B;  1MR6 A;  2CCX A;  1TXA A;  5DZ5 A;  1KFH A;  3NDS A;  1CRF A;  2QJ9 C;  1IQ9 A;  3HH7 A;  4XJJ A;  2VLW A;  2MHY A;  3KFD E; 
#chains in the Genus database with same CATH homology
 2MUP A;  2BHI A;  1ERA A;  2FD6 U;  1KS6 A;  2MJY A;  2QC1 A;  1HAJ A;  4OM5 A;  2PJY C;  4FAO E;  2N99 A;  1DRS A;  2H62 D;  1ES7 B;  1TXB A;  1JE9 A;  4LFT A;  2CRT A;  3U73 U;  1G6M A;  1KC4 A;  1RGJ A;  1ONJ A;  2CDX A;  1BTE A;  1FSC A;  2MJ0 A;  2LCR A;  5DO6 A;  2ERA A;  1IDG A;  1S4Y A;  5IMY C;  1YWH A;  3QB4 B;  1CXO A;  1QKD A;  1NTN A;  2H64 B;  2CRS A;  2H5F A;  1W6B A;  2OFS A;  2MUO A;  1HC9 B;  2QJB C;  6EBX A;  3BT1 U;  4BDT B;  2UWR A;  3NEQ A;  3BT2 U;  3LAQ U;  4OM4 A;  2QJA C;  1KBA A;  1IKC A;  2LA1 A;  1IDL A;  1UG4 A;  1ZAD A;  1L4W A;  4ZQY A;  1F94 A;  1M9Z A;  1IK8 A;  1CTX A;  1XT3 A;  2MFA A;  1JGK A;  1NXB A;  3EVS C;  5IMT D;  2GOO C;  1LSI A;  1LXH A;  1CXN A;  1KBT A;  1FFJ A;  1FSS B;  1IJC A;  2H62 C;  1BXP A;  1HC9 A;  1NOR A;  1FAS A;  3KFD I;  2HLQ A;  1KXI A;  4AEA A;  2H8U A;  1ERG A;  4DO8 A;  1F8U B;  3EBX A;  1CDT A;  2H7Z B;  4RUD A;  1H0J A;  2X8B B;  2BTX A;  1CHV S;  4HQP F;  1LX5 B;  3U74 U;  1NEA A;  1CDS A;  2K3G A;  1FF4 A;  1B41 B;  3ERA A;  1CDQ A;  1CB9 A;  1RL5 A;  3VTS A;  2J8B A;  1KBS A;  1VB0 A;  1CCQ A;  1JBD A;  2I9B E;  2PJY B;  3PLC A;  1TGX A;  4IYE A;  4P7U A;  4UY2 C;  1NYU A;  1MAH F;  1REW C;  4KSN A;  1FRA A;  5EBX A;  5DU1 A;  3NH7 A;  2MJ4 A;  1HOY A;  1NYS A;  2GOO B;  2ABX A;  1TFS A;  1NTX A;  2H7Z A;  1LJZ A;  1IDH A;  1PLO A;  1COE A;  4FAO C;  1KU6 B;  1LXG A;  1CRE A;  2HLR A;  1KL8 A;  4QTI U;  1QM7 A;  2JQP A;  1HAA A;  4BIK B;  1ABT A;  1CDR A;  1CVO A;  2NBT A;  2UX2 A;  1KTZ B;  1V6P A;  1IDI A;  3FEV A;  2L5S A;  2CTX A;  1I02 A;  2H64 C;  1COD A;  2L03 A;  2JVE A;  1QKE A;  4EY8 B;  1MR6 A;  2CCX A;  1TXA A;  5DZ5 A;  1KFH A;  3NDS A;  1CRF A;  2QJ9 C;  1IQ9 A;  3HH7 A;  4XJJ A;  2VLW A;  2MHY A;  3KFD E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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