1TGXA

X-ray structure at 1.55 a of toxin gamma, a cardiotoxin from naja nigricollis venom. crystal packing reveals a model for insertion into membranes
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
60
structure length
60
Chain Sequence
LKCNQLIPPFWKTCPKGKNLCYKMTMRAAPMVPVKRGCIDVCPKSSLLIKYMCCNTDKCN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray structure at 1.55 A of toxin gamma, a cardiotoxin from Naja nigricollis venom. Crystal packing reveals a model for insertion into membranes.
pubmed doi rcsb
molecule tags Cytotoxin
source organism Naja nigricollis
molecule keywords GAMMA-CARDIOTOXIN
total genus 10
structure length 60
sequence length 60
chains with identical sequence B, C
ec nomenclature
pdb deposition date 1993-11-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00087 Toxin_TOLIP Snake toxin and toxin-like protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 1tgxA00
4IYEA 1ERAA 1CXOA 1TXBA 4P7UA 2X8BB 2MJ4A 1ABTA 2HLQA 1LJZA 2LCRA 1LX5B 1CB9A 2H7ZA 4OM5A 1BXPA 1KU6B 2GOOC 2ERAA 2QJ9C 4EY8B 1JGKA 2CCXA 2MFAA 3NH7A 4DO8A 1IDIA 3EVSC 4OM4A 1KBTA 2JVEA 1NORA 1S4YA 1V6PA 1IDLA 1KFHA 2LA1A 3EBXA 1KBAA 1CODA 1L4WA 5EBXA 1RGJA 1HAAA 1KC4A 2NBTA 1KS6A 1TXAA 1RL5A 1JE9A 3U73U 2CRSA 3BT2U 1CREA 2HLRA 2BTXA 5IMYC 2PJYC 1QKDA 3FEVA 1NTNA 2MJYA 3LAQU 3HH7A 1FSSB 2K3GA 4FAOC 2H62D 1LXHA 3U74U 1CDSA 1KTZB 1I02A 1NEAA 2L03A 3BT1U 1IJCA 1FRAA 1W6BA 1IKCA 4XJJA 3QB4B 2JQPA 1IDGA 3VTSA 1DRSA 1HC9B 1CXNA 4FAOE 1UG4A 2FD6U 1HAJA 1PLOA 1CTXA 2H64C 1TFSA 2J8BA 1LXGA 5IMTD 1CVOA 2QJBC 3KFDE 3PLCA 1TGXA 1HC9A 4RUDA 1IQ9A 1QM7A 2BHIA 1FASA 2UWRA 1CDRA 1CHVS 1CDTA 1QKEA 1MAHF 1VB0A 2CRTA 1XT3A 4LFTA 2CDXA 6EBXA 4AEAA 4BIKB 4HQPF 2ABXA 4ZQYA 2PJYB 1F94A 2QJAC 1BTEA 1KBSA 2MUOA 1KL8A 1NYUA 1NYSA 2GOOB 1JBDA 1IK8A 1ERGA 3ERAA 1HOYA 1IDHA 1F8UB 1ONJA 1LSIA 1NTXA 1FSCA 2QC1A 5DO6A 2MJ0A 1ZADA 1FF4A 1H0JA 1REWC 2OFSA 2L5SA 1B41B 2MHYA 1ES7B 1M9ZA 3KFDI 3NDSA 4QTIU 4BDTB 1CCQA 5DU1A 1NXBA 2CTXA 2H64B 1MR6A 1COEA 2MUPA 1CRFA 3NEQA 1YWHA 2H8UA 2I9BE 1CDQA 2N99A 1KXIA 2UX2A 4UY2C 1G6MA 2H7ZB 2VLWA 5DZ5A 2H5FA 2H62C 1FFJA
chains in the Genus database with same CATH superfamily
4IYEA 1ERAA 1CXOA 1TXBA 4P7UA 2X8BB 2MJ4A 1ABTA 2HLQA 1LJZA 2LCRA 1LX5B 1CB9A 2H7ZA 4OM5A 1BXPA 1KU6B 2GOOC 2ERAA 2QJ9C 4EY8B 1JGKA 2CCXA 2MFAA 3NH7A 4DO8A 1IDIA 3EVSC 4OM4A 1KBTA 2JVEA 1NORA 1S4YA 1V6PA 1IDLA 1KFHA 2LA1A 3EBXA 1KBAA 1CODA 1L4WA 5EBXA 1RGJA 1HAAA 1KC4A 2NBTA 1KS6A 1TXAA 1RL5A 1JE9A 3U73U 2CRSA 3BT2U 1CREA 2HLRA 2BTXA 5IMYC 2PJYC 1QKDA 3FEVA 1NTNA 2MJYA 3LAQU 3HH7A 1FSSB 2K3GA 4FAOC 2H62D 1LXHA 3U74U 1CDSA 1KTZB 1I02A 1NEAA 2L03A 3BT1U 1IJCA 1FRAA 1W6BA 1IKCA 4XJJA 3QB4B 2JQPA 1IDGA 3VTSA 1DRSA 1HC9B 1CXNA 4FAOE 1UG4A 2FD6U 1HAJA 1PLOA 1CTXA 2H64C 1TFSA 2J8BA 1LXGA 5IMTD 1CVOA 2QJBC 3KFDE 3PLCA 1TGXA 1HC9A 4RUDA 1IQ9A 1QM7A 2BHIA 1FASA 2UWRA 1CDRA 1CHVS 1CDTA 1QKEA 1MAHF 1VB0A 2CRTA 1XT3A 4LFTA 2CDXA 6EBXA 4AEAA 4BIKB 4HQPF 2ABXA 4ZQYA 2PJYB 1F94A 2QJAC 1BTEA 1KBSA 2MUOA 1KL8A 1NYUA 1NYSA 2GOOB 1JBDA 1IK8A 1ERGA 3ERAA 1HOYA 1IDHA 1F8UB 1ONJA 1LSIA 1NTXA 1FSCA 2QC1A 5DO6A 2MJ0A 1ZADA 1FF4A 1H0JA 1REWC 2OFSA 2L5SA 1B41B 2MHYA 1ES7B 1M9ZA 3KFDI 3NDSA 4QTIU 4BDTB 1CCQA 5DU1A 1NXBA 2CTXA 2H64B 1MR6A 1COEA 2MUPA 1CRFA 3NEQA 1YWHA 2H8UA 2I9BE 1CDQA 2N99A 1KXIA 2UX2A 4UY2C 1G6MA 2H7ZB 2VLWA 5DZ5A 4KSNA 2H5FA 2H62C 1FFJA
chains in the Genus database with same CATH topology
4IYEA 1ERAA 1CXOA 1TXBA 4P7UA 2X8BB 2MJ4A 1ABTA 2HLQA 1LJZA 2LCRA 1LX5B 1CB9A 2H7ZA 4OM5A 1BXPA 1KU6B 2GOOC 2ERAA 2QJ9C 4EY8B 1JGKA 2CCXA 2MFAA 3NH7A 4DO8A 1IDIA 3EVSC 4OM4A 1KBTA 2JVEA 1NORA 1S4YA 1V6PA 1IDLA 1KFHA 2LA1A 3EBXA 1KBAA 1CODA 1L4WA 5EBXA 1RGJA 1HAAA 1KC4A 2NBTA 1KS6A 1TXAA 1RL5A 1JE9A 3U73U 2CRSA 3BT2U 1CREA 2HLRA 2BTXA 5IMYC 2PJYC 1QKDA 3FEVA 1NTNA 2MJYA 3LAQU 3HH7A 1FSSB 2K3GA 4FAOC 2H62D 1LXHA 3U74U 1CDSA 1KTZB 1I02A 1NEAA 2L03A 3BT1U 1IJCA 1FRAA 1W6BA 1IKCA 4XJJA 3QB4B 2JQPA 1IDGA 3VTSA 1DRSA 1HC9B 1CXNA 4FAOE 1UG4A 2FD6U 1HAJA 1PLOA 1CTXA 2H64C 1TFSA 2J8BA 1LXGA 5IMTD 1CVOA 2QJBC 3KFDE 3PLCA 1TGXA 1HC9A 4RUDA 1IQ9A 1QM7A 2BHIA 1FASA 2UWRA 1CDRA 1CHVS 1CDTA 1QKEA 1MAHF 1VB0A 2CRTA 1XT3A 4LFTA 2CDXA 6EBXA 4AEAA 4BIKB 4HQPF 2ABXA 4ZQYA 2PJYB 1F94A 2QJAC 1BTEA 1KBSA 2MUOA 1KL8A 1NYUA 1NYSA 2GOOB 1JBDA 1IK8A 1ERGA 3ERAA 1HOYA 1IDHA 1F8UB 1ONJA 1LSIA 1NTXA 1FSCA 2QC1A 5DO6A 2MJ0A 1ZADA 1FF4A 1H0JA 1REWC 2OFSA 2L5SA 1B41B 2MHYA 1ES7B 1M9ZA 3KFDI 3NDSA 4QTIU 4BDTB 1CCQA 5DU1A 1NXBA 2CTXA 2H64B 1MR6A 1COEA 2MUPA 1CRFA 3NEQA 1YWHA 2H8UA 2I9BE 1CDQA 2N99A 1KXIA 2UX2A 4UY2C 1G6MA 2H7ZB 2VLWA 5DZ5A 4KSNA 2H5FA 2H62C 1FFJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IYE A;  1ERA A;  1CXO A;  1TXB A;  4P7U A;  2X8B B;  2MJ4 A;  1ABT A;  2HLQ A;  1LJZ A;  2LCR A;  1LX5 B;  1CB9 A;  2H7Z A;  4OM5 A;  1BXP A;  1KU6 B;  2GOO C;  2ERA A;  2QJ9 C;  4EY8 B;  1JGK A;  2CCX A;  2MFA A;  3NH7 A;  4DO8 A;  1IDI A;  3EVS C;  4OM4 A;  1KBT A;  2JVE A;  1NOR A;  1S4Y A;  1V6P A;  1IDL A;  1KFH A;  2LA1 A;  3EBX A;  1KBA A;  1COD A;  1L4W A;  5EBX A;  1RGJ A;  1HAA A;  1KC4 A;  2NBT A;  1KS6 A;  1TXA A;  1RL5 A;  1JE9 A;  3U73 U;  2CRS A;  3BT2 U;  1CRE A;  2HLR A;  2BTX A;  5IMY C;  2PJY C;  1QKD A;  3FEV A;  1NTN A;  2MJY A;  3LAQ U;  3HH7 A;  1FSS B;  2K3G A;  4FAO C;  2H62 D;  1LXH A;  3U74 U;  1CDS A;  1KTZ B;  1I02 A;  1NEA A;  2L03 A;  3BT1 U;  1IJC A;  1FRA A;  1W6B A;  1IKC A;  4XJJ A;  3QB4 B;  2JQP A;  1IDG A;  3VTS A;  1DRS A;  1HC9 B;  1CXN A;  4FAO E;  1UG4 A;  2FD6 U;  1HAJ A;  1PLO A;  1CTX A;  2H64 C;  1TFS A;  2J8B A;  1LXG A;  5IMT D;  1CVO A;  2QJB C;  3KFD E;  3PLC A;  1TGX A;  1HC9 A;  4RUD A;  1IQ9 A;  1QM7 A;  2BHI A;  1FAS A;  2UWR A;  1CDR A;  1CHV S;  1CDT A;  1QKE A;  1MAH F;  1VB0 A;  2CRT A;  1XT3 A;  4LFT A;  2CDX A;  6EBX A;  4AEA A;  4BIK B;  4HQP F;  2ABX A;  4ZQY A;  2PJY B;  1F94 A;  2QJA C;  1BTE A;  1KBS A;  2MUO A;  1KL8 A;  1NYU A;  1NYS A;  2GOO B;  1JBD A;  1IK8 A;  1ERG A;  3ERA A;  1HOY A;  1IDH A;  1F8U B;  1ONJ A;  1LSI A;  1NTX A;  1FSC A;  2QC1 A;  5DO6 A;  2MJ0 A;  1ZAD A;  1FF4 A;  1H0J A;  1REW C;  2OFS A;  2L5S A;  1B41 B;  2MHY A;  1ES7 B;  1M9Z A;  3KFD I;  3NDS A;  4QTI U;  4BDT B;  1CCQ A;  5DU1 A;  1NXB A;  2CTX A;  2H64 B;  1MR6 A;  1COE A;  2MUP A;  1CRF A;  3NEQ A;  1YWH A;  2H8U A;  2I9B E;  1CDQ A;  2N99 A;  1KXI A;  2UX2 A;  4UY2 C;  1G6M A;  2H7Z B;  2VLW A;  5DZ5 A;  2H5F A;  2H62 C;  1FFJ A; 
#chains in the Genus database with same CATH topology
 4IYE A;  1ERA A;  1CXO A;  1TXB A;  4P7U A;  2X8B B;  2MJ4 A;  1ABT A;  2HLQ A;  1LJZ A;  2LCR A;  1LX5 B;  1CB9 A;  2H7Z A;  4OM5 A;  1BXP A;  1KU6 B;  2GOO C;  2ERA A;  2QJ9 C;  4EY8 B;  1JGK A;  2CCX A;  2MFA A;  3NH7 A;  4DO8 A;  1IDI A;  3EVS C;  4OM4 A;  1KBT A;  2JVE A;  1NOR A;  1S4Y A;  1V6P A;  1IDL A;  1KFH A;  2LA1 A;  3EBX A;  1KBA A;  1COD A;  1L4W A;  5EBX A;  1RGJ A;  1HAA A;  1KC4 A;  2NBT A;  1KS6 A;  1TXA A;  1RL5 A;  1JE9 A;  3U73 U;  2CRS A;  3BT2 U;  1CRE A;  2HLR A;  2BTX A;  5IMY C;  2PJY C;  1QKD A;  3FEV A;  1NTN A;  2MJY A;  3LAQ U;  3HH7 A;  1FSS B;  2K3G A;  4FAO C;  2H62 D;  1LXH A;  3U74 U;  1CDS A;  1KTZ B;  1I02 A;  1NEA A;  2L03 A;  3BT1 U;  1IJC A;  1FRA A;  1W6B A;  1IKC A;  4XJJ A;  3QB4 B;  2JQP A;  1IDG A;  3VTS A;  1DRS A;  1HC9 B;  1CXN A;  4FAO E;  1UG4 A;  2FD6 U;  1HAJ A;  1PLO A;  1CTX A;  2H64 C;  1TFS A;  2J8B A;  1LXG A;  5IMT D;  1CVO A;  2QJB C;  3KFD E;  3PLC A;  1TGX A;  1HC9 A;  4RUD A;  1IQ9 A;  1QM7 A;  2BHI A;  1FAS A;  2UWR A;  1CDR A;  1CHV S;  1CDT A;  1QKE A;  1MAH F;  1VB0 A;  2CRT A;  1XT3 A;  4LFT A;  2CDX A;  6EBX A;  4AEA A;  4BIK B;  4HQP F;  2ABX A;  4ZQY A;  2PJY B;  1F94 A;  2QJA C;  1BTE A;  1KBS A;  2MUO A;  1KL8 A;  1NYU A;  1NYS A;  2GOO B;  1JBD A;  1IK8 A;  1ERG A;  3ERA A;  1HOY A;  1IDH A;  1F8U B;  1ONJ A;  1LSI A;  1NTX A;  1FSC A;  2QC1 A;  5DO6 A;  2MJ0 A;  1ZAD A;  1FF4 A;  1H0J A;  1REW C;  2OFS A;  2L5S A;  1B41 B;  2MHY A;  1ES7 B;  1M9Z A;  3KFD I;  3NDS A;  4QTI U;  4BDT B;  1CCQ A;  5DU1 A;  1NXB A;  2CTX A;  2H64 B;  1MR6 A;  1COE A;  2MUP A;  1CRF A;  3NEQ A;  1YWH A;  2H8U A;  2I9B E;  1CDQ A;  2N99 A;  1KXI A;  2UX2 A;  4UY2 C;  1G6M A;  2H7Z B;  2VLW A;  5DZ5 A;  4KSN A;  2H5F A;  2H62 C;  1FFJ A; 
#chains in the Genus database with same CATH homology
 4IYE A;  1ERA A;  1CXO A;  1TXB A;  4P7U A;  2X8B B;  2MJ4 A;  1ABT A;  2HLQ A;  1LJZ A;  2LCR A;  1LX5 B;  1CB9 A;  2H7Z A;  4OM5 A;  1BXP A;  1KU6 B;  2GOO C;  2ERA A;  2QJ9 C;  4EY8 B;  1JGK A;  2CCX A;  2MFA A;  3NH7 A;  4DO8 A;  1IDI A;  3EVS C;  4OM4 A;  1KBT A;  2JVE A;  1NOR A;  1S4Y A;  1V6P A;  1IDL A;  1KFH A;  2LA1 A;  3EBX A;  1KBA A;  1COD A;  1L4W A;  5EBX A;  1RGJ A;  1HAA A;  1KC4 A;  2NBT A;  1KS6 A;  1TXA A;  1RL5 A;  1JE9 A;  3U73 U;  2CRS A;  3BT2 U;  1CRE A;  2HLR A;  2BTX A;  5IMY C;  2PJY C;  1QKD A;  3FEV A;  1NTN A;  2MJY A;  3LAQ U;  3HH7 A;  1FSS B;  2K3G A;  4FAO C;  2H62 D;  1LXH A;  3U74 U;  1CDS A;  1KTZ B;  1I02 A;  1NEA A;  2L03 A;  3BT1 U;  1IJC A;  1FRA A;  1W6B A;  1IKC A;  4XJJ A;  3QB4 B;  2JQP A;  1IDG A;  3VTS A;  1DRS A;  1HC9 B;  1CXN A;  4FAO E;  1UG4 A;  2FD6 U;  1HAJ A;  1PLO A;  1CTX A;  2H64 C;  1TFS A;  2J8B A;  1LXG A;  5IMT D;  1CVO A;  2QJB C;  3KFD E;  3PLC A;  1TGX A;  1HC9 A;  4RUD A;  1IQ9 A;  1QM7 A;  2BHI A;  1FAS A;  2UWR A;  1CDR A;  1CHV S;  1CDT A;  1QKE A;  1MAH F;  1VB0 A;  2CRT A;  1XT3 A;  4LFT A;  2CDX A;  6EBX A;  4AEA A;  4BIK B;  4HQP F;  2ABX A;  4ZQY A;  2PJY B;  1F94 A;  2QJA C;  1BTE A;  1KBS A;  2MUO A;  1KL8 A;  1NYU A;  1NYS A;  2GOO B;  1JBD A;  1IK8 A;  1ERG A;  3ERA A;  1HOY A;  1IDH A;  1F8U B;  1ONJ A;  1LSI A;  1NTX A;  1FSC A;  2QC1 A;  5DO6 A;  2MJ0 A;  1ZAD A;  1FF4 A;  1H0J A;  1REW C;  2OFS A;  2L5S A;  1B41 B;  2MHY A;  1ES7 B;  1M9Z A;  3KFD I;  3NDS A;  4QTI U;  4BDT B;  1CCQ A;  5DU1 A;  1NXB A;  2CTX A;  2H64 B;  1MR6 A;  1COE A;  2MUP A;  1CRF A;  3NEQ A;  1YWH A;  2H8U A;  2I9B E;  1CDQ A;  2N99 A;  1KXI A;  2UX2 A;  4UY2 C;  1G6M A;  2H7Z B;  2VLW A;  5DZ5 A;  4KSN A;  2H5F A;  2H62 C;  1FFJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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