1YWHA

Crystal structure of urokinase plasminogen activator receptor
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
279
structure length
268
Chain Sequence
LRCMQCKTNGDCRVEECALGQDLCRTTIVRLWEEGEELELVEKSCTHSEKTNRTLSYRTGLKITSLTEVVCGLDLCNQGNSGRSRYLECISCGSSDMSCERGRHQSLQCRSPEEQCLDVVTHWIQRPKDDRHLRGCGYLPGCPGSNGFHNNDTFHFLKCCNTTKCNEGPILELENLPQNGRQCYSCKGQSTHGCSSEETFLIDCRGPMNQCLVATGTHEPKNQSYMVRGCATASMCQHAHLGDAFSMNHIDVSCCTKSGCNHPDLDVQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the human urokinase plasminogen activator receptor bound to an antagonist peptide
pubmed doi rcsb
molecule tags Hydrolase receptor
source organism Homo sapiens
molecule keywords Urokinase plasminogen activator surface receptor
total genus 52
structure length 268
sequence length 279
chains with identical sequence C, E, G, I, K, M, O
ec nomenclature
pdb deposition date 2005-02-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00021 UPAR_LY6 u-PAR/Ly-6 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 1ywhA01
2.10.60.10 Mainly Beta Ribbon CD59 CD59 1ywhA03
2.10.60.10 Mainly Beta Ribbon CD59 CD59 1ywhA02
1NEAA 4QTIU 1IDGA 1CXOA 1KC4A 2QJAC 1HAJA 1DRSA 1H0JA 1IDHA 2ABXA 4XJJA 2K3GA 1LSIA 1PLOA 1FSCA 3NH7A 4BDTB 1BTEA 2CRSA 4AEAA 2PJYC 1ERAA 4FAOC 2ERAA 2N99A 1CTXA 1ABTA 1ZADA 2FD6U 1LXHA 1NTXA 2L03A 2CRTA 1TXBA 1ES7B 4P7UA 2CCXA 4ZQYA 2H5FA 2L5SA 1KXIA 2H62D 3VTSA 4HQPF 1CDSA 1F8UB 5DZ5A 3BT2U 2BHIA 1RL5A 1G6MA 1NTNA 1RGJA 1IK8A 1FRAA 1TFSA 2UX2A 1QKDA 1BXPA 1NYSA 4UY2C 1F94A 2MHYA 1UG4A 4OM5A 2PJYB 5DO6A 3BT1U 1FF4A 1KFHA 2BTXA 1JGKA 1FFJA 3NEQA 1CXNA 1IDIA 2UWRA 4LFTA 1CVOA 1IQ9A 1HOYA 3U74U 1CODA 4EY8B 2GOOC 2CTXA 4RUDA 1B41B 3EVSC 3EBXA 1REWC 1LXGA 1IJCA 1M9ZA 1JE9A 2JVEA 2HLRA 3KFDE 1KBSA 3ERAA 4OM4A 1ERGA 1NORA 1NYUA 2LCRA 1CCQA 2J8BA 4FAOE 1W6BA 2JQPA 1CDTA 1VB0A 2MJYA 3QB4B 3LAQU 2H62C 3PLCA 1MR6A 5IMYC 1JBDA 2H64C 5EBXA 2QC1A 2QJ9C 2LA1A 1IDLA 1XT3A 2GOOB 2VLWA 1TGXA 4BIKB 1FASA 1CHVS 2MFAA 2OFSA 3HH7A 1KL8A 1HC9B 3NDSA 6EBXA 1CDQA 1KTZB 1CREA 1HC9A 1KBAA 1ONJA 1IKCA 1CRFA 1NXBA 1LJZA 1I02A 3KFDI 1CDRA 2QJBC 1QM7A 1TXAA 1CB9A 2MUOA 2X8BB 1S4YA 1KU6B 1MAHF 1QKEA 1KBTA 2MJ4A 1KS6A 1FSSB 3U73U 5DU1A 2H8UA 2HLQA 1LX5B 2MJ0A 1L4WA 2H64B 2NBTA 4DO8A 2MUPA 1COEA 1YWHA 1V6PA 2CDXA 1HAAA 4IYEA 2I9BE 2H7ZB 5IMTD 2H7ZA 3FEVA
chains in the Genus database with same CATH superfamily
1NEAA 4QTIU 1IDGA 1CXOA 1KC4A 2QJAC 1HAJA 1DRSA 1H0JA 1IDHA 2ABXA 4XJJA 2K3GA 1LSIA 1PLOA 1FSCA 3NH7A 4BDTB 1BTEA 2CRSA 4AEAA 2PJYC 1ERAA 4FAOC 2ERAA 2N99A 1CTXA 1ABTA 1ZADA 2FD6U 1LXHA 1NTXA 2L03A 2CRTA 1TXBA 1ES7B 4P7UA 2CCXA 4ZQYA 2H5FA 2L5SA 1KXIA 2H62D 3VTSA 4HQPF 1CDSA 1F8UB 5DZ5A 3BT2U 2BHIA 1RL5A 1G6MA 1NTNA 1RGJA 1IK8A 1FRAA 1TFSA 2UX2A 1QKDA 1BXPA 1NYSA 4UY2C 1F94A 4KSNA 2MHYA 1UG4A 4OM5A 2PJYB 5DO6A 3BT1U 1FF4A 1KFHA 2BTXA 1JGKA 1FFJA 3NEQA 1CXNA 1IDIA 2UWRA 4LFTA 1CVOA 1IQ9A 1HOYA 3U74U 1CODA 4EY8B 2GOOC 2CTXA 4RUDA 1B41B 3EVSC 3EBXA 1REWC 1LXGA 1IJCA 1M9ZA 1JE9A 2JVEA 2HLRA 3KFDE 1KBSA 3ERAA 4OM4A 1ERGA 1NORA 1NYUA 2LCRA 1CCQA 2J8BA 4FAOE 1W6BA 2JQPA 1CDTA 1VB0A 2MJYA 3QB4B 3LAQU 2H62C 3PLCA 1MR6A 5IMYC 1JBDA 2H64C 5EBXA 2QC1A 2QJ9C 2LA1A 1IDLA 1XT3A 2GOOB 2VLWA 1TGXA 4BIKB 1FASA 1CHVS 2MFAA 2OFSA 3HH7A 1KL8A 1HC9B 3NDSA 6EBXA 1CDQA 1KTZB 1CREA 1HC9A 1KBAA 1ONJA 1IKCA 1CRFA 1NXBA 1LJZA 1I02A 3KFDI 1CDRA 2QJBC 1QM7A 1TXAA 1CB9A 2MUOA 2X8BB 1S4YA 1KU6B 1MAHF 1QKEA 1KBTA 2MJ4A 1KS6A 1FSSB 3U73U 5DU1A 2H8UA 2HLQA 1LX5B 2MJ0A 1L4WA 2H64B 2NBTA 4DO8A 2MUPA 1COEA 1YWHA 1V6PA 2CDXA 1HAAA 4IYEA 2I9BE 2H7ZB 5IMTD 2H7ZA 3FEVA
chains in the Genus database with same CATH topology
1NEAA 4QTIU 1IDGA 1CXOA 1KC4A 2QJAC 1HAJA 1DRSA 1H0JA 1IDHA 2ABXA 4XJJA 2K3GA 1LSIA 1PLOA 1FSCA 3NH7A 4BDTB 1BTEA 2CRSA 4AEAA 2PJYC 1ERAA 4FAOC 2ERAA 2N99A 1CTXA 1ABTA 1ZADA 2FD6U 1LXHA 1NTXA 2L03A 2CRTA 1TXBA 1ES7B 4P7UA 2CCXA 4ZQYA 2H5FA 2L5SA 1KXIA 2H62D 3VTSA 4HQPF 1CDSA 1F8UB 5DZ5A 3BT2U 2BHIA 1RL5A 1G6MA 1NTNA 1RGJA 1IK8A 1FRAA 1TFSA 2UX2A 1QKDA 1BXPA 1NYSA 4UY2C 1F94A 4KSNA 2MHYA 1UG4A 4OM5A 2PJYB 5DO6A 3BT1U 1FF4A 1KFHA 2BTXA 1JGKA 1FFJA 3NEQA 1CXNA 1IDIA 2UWRA 4LFTA 1CVOA 1IQ9A 1HOYA 3U74U 1CODA 4EY8B 2GOOC 2CTXA 4RUDA 1B41B 3EVSC 3EBXA 1REWC 1LXGA 1IJCA 1M9ZA 1JE9A 2JVEA 2HLRA 3KFDE 1KBSA 3ERAA 4OM4A 1ERGA 1NORA 1NYUA 2LCRA 1CCQA 2J8BA 4FAOE 1W6BA 2JQPA 1CDTA 1VB0A 2MJYA 3QB4B 3LAQU 2H62C 3PLCA 1MR6A 5IMYC 1JBDA 2H64C 5EBXA 2QC1A 2QJ9C 2LA1A 1IDLA 1XT3A 2GOOB 2VLWA 1TGXA 4BIKB 1FASA 1CHVS 2MFAA 2OFSA 3HH7A 1KL8A 1HC9B 3NDSA 6EBXA 1CDQA 1KTZB 1CREA 1HC9A 1KBAA 1ONJA 1IKCA 1CRFA 1NXBA 1LJZA 1I02A 3KFDI 1CDRA 2QJBC 1QM7A 1TXAA 1CB9A 2MUOA 2X8BB 1S4YA 1KU6B 1MAHF 1QKEA 1KBTA 2MJ4A 1KS6A 1FSSB 3U73U 5DU1A 2H8UA 2HLQA 1LX5B 2MJ0A 1L4WA 2H64B 2NBTA 4DO8A 2MUPA 1COEA 1YWHA 1V6PA 2CDXA 1HAAA 4IYEA 2I9BE 2H7ZB 5IMTD 2H7ZA 3FEVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NEA A;  4QTI U;  1IDG A;  1CXO A;  1KC4 A;  2QJA C;  1HAJ A;  1DRS A;  1H0J A;  1IDH A;  2ABX A;  4XJJ A;  2K3G A;  1LSI A;  1PLO A;  1FSC A;  3NH7 A;  4BDT B;  1BTE A;  2CRS A;  4AEA A;  2PJY C;  1ERA A;  4FAO C;  2ERA A;  2N99 A;  1CTX A;  1ABT A;  1ZAD A;  2FD6 U;  1LXH A;  1NTX A;  2L03 A;  2CRT A;  1TXB A;  1ES7 B;  4P7U A;  2CCX A;  4ZQY A;  2H5F A;  2L5S A;  1KXI A;  2H62 D;  3VTS A;  4HQP F;  1CDS A;  1F8U B;  5DZ5 A;  3BT2 U;  2BHI A;  1RL5 A;  1G6M A;  1NTN A;  1RGJ A;  1IK8 A;  1FRA A;  1TFS A;  2UX2 A;  1QKD A;  1BXP A;  1NYS A;  4UY2 C;  1F94 A;  2MHY A;  1UG4 A;  4OM5 A;  2PJY B;  5DO6 A;  3BT1 U;  1FF4 A;  1KFH A;  2BTX A;  1JGK A;  1FFJ A;  3NEQ A;  1CXN A;  1IDI A;  2UWR A;  4LFT A;  1CVO A;  1IQ9 A;  1HOY A;  3U74 U;  1COD A;  4EY8 B;  2GOO C;  2CTX A;  4RUD A;  1B41 B;  3EVS C;  3EBX A;  1REW C;  1LXG A;  1IJC A;  1M9Z A;  1JE9 A;  2JVE A;  2HLR A;  3KFD E;  1KBS A;  3ERA A;  4OM4 A;  1ERG A;  1NOR A;  1NYU A;  2LCR A;  1CCQ A;  2J8B A;  4FAO E;  1W6B A;  2JQP A;  1CDT A;  1VB0 A;  2MJY A;  3QB4 B;  3LAQ U;  2H62 C;  3PLC A;  1MR6 A;  5IMY C;  1JBD A;  2H64 C;  5EBX A;  2QC1 A;  2QJ9 C;  2LA1 A;  1IDL A;  1XT3 A;  2GOO B;  2VLW A;  1TGX A;  4BIK B;  1FAS A;  1CHV S;  2MFA A;  2OFS A;  3HH7 A;  1KL8 A;  1HC9 B;  3NDS A;  6EBX A;  1CDQ A;  1KTZ B;  1CRE A;  1HC9 A;  1KBA A;  1ONJ A;  1IKC A;  1CRF A;  1NXB A;  1LJZ A;  1I02 A;  3KFD I;  1CDR A;  2QJB C;  1QM7 A;  1TXA A;  1CB9 A;  2MUO A;  2X8B B;  1S4Y A;  1KU6 B;  1MAH F;  1QKE A;  1KBT A;  2MJ4 A;  1KS6 A;  1FSS B;  3U73 U;  5DU1 A;  2H8U A;  2HLQ A;  1LX5 B;  2MJ0 A;  1L4W A;  2H64 B;  2NBT A;  4DO8 A;  2MUP A;  1COE A;  1YWH A;  1V6P A;  2CDX A;  1HAA A;  4IYE A;  2I9B E;  2H7Z B;  5IMT D;  2H7Z A;  3FEV A; 
#chains in the Genus database with same CATH topology
 1NEA A;  4QTI U;  1IDG A;  1CXO A;  1KC4 A;  2QJA C;  1HAJ A;  1DRS A;  1H0J A;  1IDH A;  2ABX A;  4XJJ A;  2K3G A;  1LSI A;  1PLO A;  1FSC A;  3NH7 A;  4BDT B;  1BTE A;  2CRS A;  4AEA A;  2PJY C;  1ERA A;  4FAO C;  2ERA A;  2N99 A;  1CTX A;  1ABT A;  1ZAD A;  2FD6 U;  1LXH A;  1NTX A;  2L03 A;  2CRT A;  1TXB A;  1ES7 B;  4P7U A;  2CCX A;  4ZQY A;  2H5F A;  2L5S A;  1KXI A;  2H62 D;  3VTS A;  4HQP F;  1CDS A;  1F8U B;  5DZ5 A;  3BT2 U;  2BHI A;  1RL5 A;  1G6M A;  1NTN A;  1RGJ A;  1IK8 A;  1FRA A;  1TFS A;  2UX2 A;  1QKD A;  1BXP A;  1NYS A;  4UY2 C;  1F94 A;  4KSN A;  2MHY A;  1UG4 A;  4OM5 A;  2PJY B;  5DO6 A;  3BT1 U;  1FF4 A;  1KFH A;  2BTX A;  1JGK A;  1FFJ A;  3NEQ A;  1CXN A;  1IDI A;  2UWR A;  4LFT A;  1CVO A;  1IQ9 A;  1HOY A;  3U74 U;  1COD A;  4EY8 B;  2GOO C;  2CTX A;  4RUD A;  1B41 B;  3EVS C;  3EBX A;  1REW C;  1LXG A;  1IJC A;  1M9Z A;  1JE9 A;  2JVE A;  2HLR A;  3KFD E;  1KBS A;  3ERA A;  4OM4 A;  1ERG A;  1NOR A;  1NYU A;  2LCR A;  1CCQ A;  2J8B A;  4FAO E;  1W6B A;  2JQP A;  1CDT A;  1VB0 A;  2MJY A;  3QB4 B;  3LAQ U;  2H62 C;  3PLC A;  1MR6 A;  5IMY C;  1JBD A;  2H64 C;  5EBX A;  2QC1 A;  2QJ9 C;  2LA1 A;  1IDL A;  1XT3 A;  2GOO B;  2VLW A;  1TGX A;  4BIK B;  1FAS A;  1CHV S;  2MFA A;  2OFS A;  3HH7 A;  1KL8 A;  1HC9 B;  3NDS A;  6EBX A;  1CDQ A;  1KTZ B;  1CRE A;  1HC9 A;  1KBA A;  1ONJ A;  1IKC A;  1CRF A;  1NXB A;  1LJZ A;  1I02 A;  3KFD I;  1CDR A;  2QJB C;  1QM7 A;  1TXA A;  1CB9 A;  2MUO A;  2X8B B;  1S4Y A;  1KU6 B;  1MAH F;  1QKE A;  1KBT A;  2MJ4 A;  1KS6 A;  1FSS B;  3U73 U;  5DU1 A;  2H8U A;  2HLQ A;  1LX5 B;  2MJ0 A;  1L4W A;  2H64 B;  2NBT A;  4DO8 A;  2MUP A;  1COE A;  1YWH A;  1V6P A;  2CDX A;  1HAA A;  4IYE A;  2I9B E;  2H7Z B;  5IMT D;  2H7Z A;  3FEV A; 
#chains in the Genus database with same CATH homology
 1NEA A;  4QTI U;  1IDG A;  1CXO A;  1KC4 A;  2QJA C;  1HAJ A;  1DRS A;  1H0J A;  1IDH A;  2ABX A;  4XJJ A;  2K3G A;  1LSI A;  1PLO A;  1FSC A;  3NH7 A;  4BDT B;  1BTE A;  2CRS A;  4AEA A;  2PJY C;  1ERA A;  4FAO C;  2ERA A;  2N99 A;  1CTX A;  1ABT A;  1ZAD A;  2FD6 U;  1LXH A;  1NTX A;  2L03 A;  2CRT A;  1TXB A;  1ES7 B;  4P7U A;  2CCX A;  4ZQY A;  2H5F A;  2L5S A;  1KXI A;  2H62 D;  3VTS A;  4HQP F;  1CDS A;  1F8U B;  5DZ5 A;  3BT2 U;  2BHI A;  1RL5 A;  1G6M A;  1NTN A;  1RGJ A;  1IK8 A;  1FRA A;  1TFS A;  2UX2 A;  1QKD A;  1BXP A;  1NYS A;  4UY2 C;  1F94 A;  4KSN A;  2MHY A;  1UG4 A;  4OM5 A;  2PJY B;  5DO6 A;  3BT1 U;  1FF4 A;  1KFH A;  2BTX A;  1JGK A;  1FFJ A;  3NEQ A;  1CXN A;  1IDI A;  2UWR A;  4LFT A;  1CVO A;  1IQ9 A;  1HOY A;  3U74 U;  1COD A;  4EY8 B;  2GOO C;  2CTX A;  4RUD A;  1B41 B;  3EVS C;  3EBX A;  1REW C;  1LXG A;  1IJC A;  1M9Z A;  1JE9 A;  2JVE A;  2HLR A;  3KFD E;  1KBS A;  3ERA A;  4OM4 A;  1ERG A;  1NOR A;  1NYU A;  2LCR A;  1CCQ A;  2J8B A;  4FAO E;  1W6B A;  2JQP A;  1CDT A;  1VB0 A;  2MJY A;  3QB4 B;  3LAQ U;  2H62 C;  3PLC A;  1MR6 A;  5IMY C;  1JBD A;  2H64 C;  5EBX A;  2QC1 A;  2QJ9 C;  2LA1 A;  1IDL A;  1XT3 A;  2GOO B;  2VLW A;  1TGX A;  4BIK B;  1FAS A;  1CHV S;  2MFA A;  2OFS A;  3HH7 A;  1KL8 A;  1HC9 B;  3NDS A;  6EBX A;  1CDQ A;  1KTZ B;  1CRE A;  1HC9 A;  1KBA A;  1ONJ A;  1IKC A;  1CRF A;  1NXB A;  1LJZ A;  1I02 A;  3KFD I;  1CDR A;  2QJB C;  1QM7 A;  1TXA A;  1CB9 A;  2MUO A;  2X8B B;  1S4Y A;  1KU6 B;  1MAH F;  1QKE A;  1KBT A;  2MJ4 A;  1KS6 A;  1FSS B;  3U73 U;  5DU1 A;  2H8U A;  2HLQ A;  1LX5 B;  2MJ0 A;  1L4W A;  2H64 B;  2NBT A;  4DO8 A;  2MUP A;  1COE A;  1YWH A;  1V6P A;  2CDX A;  1HAA A;  4IYE A;  2I9B E;  2H7Z B;  5IMT D;  2H7Z A;  3FEV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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