1COEA

Solution conformation of cobrotoxin: a nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing study
Total Genus 5

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
62
structure length
62
Chain Sequence
LECHNQQSSQTPTTTGCSGGETNCYKKRWRDHRGYRTERGCGCPSVKNGIEINCCTTDRCNN

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
EMPTYTIV6 (57-60)S1 (4-5)S2 (13-14)TI'1 (18-21)S3 (24-31)S5 (51-55)S4 (34-38)Updating...
connected with : NaN
molecule tags Short neurotoxin
source organism Naja atra
publication title Solution conformation of cobrotoxin: a nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing study.
pubmed doi rcsb
molecule keywords COBROTOXIN
total genus 5
structure length 62
sequence length 62
ec nomenclature
pdb deposition date 1994-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00087 Toxin_TOLIP Snake toxin and toxin-like protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 1coeA00
1M9ZA 2MUPA 2BTXA 2H64B 1CTXA 3EVSC 3VTSA 1RGJA 1IDIA 2FD6U 1IDLA 2GOOC 1ABTA 2H7ZB 3ERAA 4RUDA 2MJ4A 2H8UA 1MAHF 1CXNA 2MFAA 4AEAA 1REWC 1ERGA 1CODA 1I02A 1IQ9A 1CVOA 3KFDI 2QJBC 1LSIA 5DU1A 4EY8B 2LCRA 1CRFA 1ONJA 2UX2A 1BXPA 1CDTA 2QC1A 1QM7A 5IMTD 3QB4B 1ES7B 1KU6B 4P7UA 3NH7A 5EBXA 1KC4A 1S4YA 2MJ0A 1KXIA 1HC9A 2J8BA 1CCQA 2H5FA 2JVEA 1NEAA 1VB0A 1LJZA 2L03A 2CDXA 1CDSA 1TXAA 1H0JA 2OFSA 2N99A 2H62C 1KTZB 1KS6A 3EBXA 2MHYA 2CTXA 5IMYC 1BTEA 2MJYA 1XT3A 2PJYB 3BT2U 1L4WA 1FSCA 2H62D 4LFTA 1FRAA 1IDHA 1HAJA 1NTNA 2HLRA 2VLWA 1KL8A 4UY2C 2BHIA 1PLOA 3KFDE 4BDTB 2I9BE 1CDQA 2JQPA 2ERAA 1KBSA 2QJAC 1CHVS 1IK8A 1FASA 2ABXA 2X8BB 1IKCA 1COEA 1NYSA 1ERAA 4OM5A 1HC9B 1NYUA 1MR6A 4XJJA 1TGXA 4BIKB 1CREA 1QKDA 1V6PA 2CRTA 1TXBA 1NTXA 2QJ9C 1KFHA 1FSSB 1KBTA 2GOOB 1JGKA 1FF4A 1KBAA 6EBXA 1CXOA 2HLQA 3HH7A 3NDSA 1CB9A 1LX5B 2H64C 1YWHA 3U74U 4FAOC 5DO6A 3U73U 1NORA 2CCXA 3LAQU 1HOYA 4ZQYA 2H7ZA 2L5SA 1RL5A 4FAOE 2K3GA 2NBTA 2PJYC 4OM4A 1JE9A 2LA1A 2MUOA 2CRSA 3NEQA 4QTIU 4IYEA 1ZADA 1IDGA 1LXGA 1QKEA 3FEVA 4HQPF 1HAAA 4DO8A 1FFJA 1F94A 5DZ5A 1CDRA 1LXHA 2UWRA 1IJCA 3PLCA 1G6MA 1NXBA 1DRSA 3BT1U 1TFSA 1W6BA 1JBDA 1UG4A 1B41B 1F8UB
chains in the Genus database with same CATH superfamily
1M9ZA 2MUPA 2BTXA 2H64B 1CTXA 3EVSC 3VTSA 1RGJA 1IDIA 2FD6U 1IDLA 2GOOC 1ABTA 2H7ZB 3ERAA 4RUDA 2MJ4A 2H8UA 1MAHF 1CXNA 2MFAA 4KSNA 4AEAA 1REWC 1ERGA 1CODA 1I02A 1IQ9A 1CVOA 3KFDI 2QJBC 1LSIA 5DU1A 4EY8B 2LCRA 1CRFA 1ONJA 2UX2A 1BXPA 1CDTA 2QC1A 1QM7A 5IMTD 3QB4B 1ES7B 1KU6B 4P7UA 3NH7A 5EBXA 1KC4A 1S4YA 2MJ0A 1KXIA 1HC9A 2J8BA 1CCQA 2H5FA 2JVEA 1NEAA 1VB0A 1LJZA 2L03A 2CDXA 1CDSA 1TXAA 1H0JA 2OFSA 2N99A 2H62C 1KTZB 1KS6A 3EBXA 2MHYA 2CTXA 5IMYC 1BTEA 2MJYA 1XT3A 2PJYB 3BT2U 1L4WA 1FSCA 2H62D 4LFTA 1FRAA 1IDHA 1HAJA 1NTNA 2HLRA 2VLWA 1KL8A 4UY2C 2BHIA 1PLOA 3KFDE 4BDTB 2I9BE 1CDQA 2JQPA 2ERAA 1KBSA 2QJAC 1CHVS 1IK8A 1FASA 2ABXA 2X8BB 1IKCA 1COEA 1NYSA 1ERAA 4OM5A 1HC9B 1NYUA 1MR6A 4XJJA 1TGXA 4BIKB 1CREA 1QKDA 1V6PA 2CRTA 1TXBA 1NTXA 2QJ9C 1KFHA 1FSSB 1KBTA 2GOOB 1JGKA 1FF4A 1KBAA 6EBXA 1CXOA 2HLQA 3HH7A 3NDSA 1CB9A 1LX5B 2H64C 1YWHA 3U74U 4FAOC 5DO6A 3U73U 1NORA 2CCXA 3LAQU 1HOYA 4ZQYA 2H7ZA 2L5SA 1RL5A 4FAOE 2K3GA 2NBTA 2PJYC 4OM4A 1JE9A 2LA1A 2MUOA 2CRSA 3NEQA 4QTIU 4IYEA 1ZADA 1IDGA 1LXGA 1QKEA 3FEVA 4HQPF 1HAAA 4DO8A 1FFJA 1F94A 5DZ5A 1CDRA 1LXHA 2UWRA 1IJCA 3PLCA 1G6MA 1NXBA 1DRSA 3BT1U 1TFSA 1W6BA 1JBDA 1UG4A 1B41B 1F8UB
chains in the Genus database with same CATH topology
1M9ZA 2MUPA 2BTXA 2H64B 1CTXA 3EVSC 3VTSA 1RGJA 1IDIA 2FD6U 1IDLA 2GOOC 1ABTA 2H7ZB 3ERAA 4RUDA 2MJ4A 2H8UA 1MAHF 1CXNA 2MFAA 4KSNA 4AEAA 1REWC 1ERGA 1CODA 1I02A 1IQ9A 1CVOA 3KFDI 2QJBC 1LSIA 5DU1A 4EY8B 2LCRA 1CRFA 1ONJA 2UX2A 1BXPA 1CDTA 2QC1A 1QM7A 5IMTD 3QB4B 1ES7B 1KU6B 4P7UA 3NH7A 5EBXA 1KC4A 1S4YA 2MJ0A 1KXIA 1HC9A 2J8BA 1CCQA 2H5FA 2JVEA 1NEAA 1VB0A 1LJZA 2L03A 2CDXA 1CDSA 1TXAA 1H0JA 2OFSA 2N99A 2H62C 1KTZB 1KS6A 3EBXA 2MHYA 2CTXA 5IMYC 1BTEA 2MJYA 1XT3A 2PJYB 3BT2U 1L4WA 1FSCA 2H62D 4LFTA 1FRAA 1IDHA 1HAJA 1NTNA 2HLRA 2VLWA 1KL8A 4UY2C 2BHIA 1PLOA 3KFDE 4BDTB 2I9BE 1CDQA 2JQPA 2ERAA 1KBSA 2QJAC 1CHVS 1IK8A 1FASA 2ABXA 2X8BB 1IKCA 1COEA 1NYSA 1ERAA 4OM5A 1HC9B 1NYUA 1MR6A 4XJJA 1TGXA 4BIKB 1CREA 1QKDA 1V6PA 2CRTA 1TXBA 1NTXA 2QJ9C 1KFHA 1FSSB 1KBTA 2GOOB 1JGKA 1FF4A 1KBAA 6EBXA 1CXOA 2HLQA 3HH7A 3NDSA 1CB9A 1LX5B 2H64C 1YWHA 3U74U 4FAOC 5DO6A 3U73U 1NORA 2CCXA 3LAQU 1HOYA 4ZQYA 2H7ZA 2L5SA 1RL5A 4FAOE 2K3GA 2NBTA 2PJYC 4OM4A 1JE9A 2LA1A 2MUOA 2CRSA 3NEQA 4QTIU 4IYEA 1ZADA 1IDGA 1LXGA 1QKEA 3FEVA 4HQPF 1HAAA 4DO8A 1FFJA 1F94A 5DZ5A 1CDRA 1LXHA 2UWRA 1IJCA 3PLCA 1G6MA 1NXBA 1DRSA 3BT1U 1TFSA 1W6BA 1JBDA 1UG4A 1B41B 1F8UB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M9Z A;  2MUP A;  2BTX A;  2H64 B;  1CTX A;  3EVS C;  3VTS A;  1RGJ A;  1IDI A;  2FD6 U;  1IDL A;  2GOO C;  1ABT A;  2H7Z B;  3ERA A;  4RUD A;  2MJ4 A;  2H8U A;  1MAH F;  1CXN A;  2MFA A;  4AEA A;  1REW C;  1ERG A;  1COD A;  1I02 A;  1IQ9 A;  1CVO A;  3KFD I;  2QJB C;  1LSI A;  5DU1 A;  4EY8 B;  2LCR A;  1CRF A;  1ONJ A;  2UX2 A;  1BXP A;  1CDT A;  2QC1 A;  1QM7 A;  5IMT D;  3QB4 B;  1ES7 B;  1KU6 B;  4P7U A;  3NH7 A;  5EBX A;  1KC4 A;  1S4Y A;  2MJ0 A;  1KXI A;  1HC9 A;  2J8B A;  1CCQ A;  2H5F A;  2JVE A;  1NEA A;  1VB0 A;  1LJZ A;  2L03 A;  2CDX A;  1CDS A;  1TXA A;  1H0J A;  2OFS A;  2N99 A;  2H62 C;  1KTZ B;  1KS6 A;  3EBX A;  2MHY A;  2CTX A;  5IMY C;  1BTE A;  2MJY A;  1XT3 A;  2PJY B;  3BT2 U;  1L4W A;  1FSC A;  2H62 D;  4LFT A;  1FRA A;  1IDH A;  1HAJ A;  1NTN A;  2HLR A;  2VLW A;  1KL8 A;  4UY2 C;  2BHI A;  1PLO A;  3KFD E;  4BDT B;  2I9B E;  1CDQ A;  2JQP A;  2ERA A;  1KBS A;  2QJA C;  1CHV S;  1IK8 A;  1FAS A;  2ABX A;  2X8B B;  1IKC A;  1COE A;  1NYS A;  1ERA A;  4OM5 A;  1HC9 B;  1NYU A;  1MR6 A;  4XJJ A;  1TGX A;  4BIK B;  1CRE A;  1QKD A;  1V6P A;  2CRT A;  1TXB A;  1NTX A;  2QJ9 C;  1KFH A;  1FSS B;  1KBT A;  2GOO B;  1JGK A;  1FF4 A;  1KBA A;  6EBX A;  1CXO A;  2HLQ A;  3HH7 A;  3NDS A;  1CB9 A;  1LX5 B;  2H64 C;  1YWH A;  3U74 U;  4FAO C;  5DO6 A;  3U73 U;  1NOR A;  2CCX A;  3LAQ U;  1HOY A;  4ZQY A;  2H7Z A;  2L5S A;  1RL5 A;  4FAO E;  2K3G A;  2NBT A;  2PJY C;  4OM4 A;  1JE9 A;  2LA1 A;  2MUO A;  2CRS A;  3NEQ A;  4QTI U;  4IYE A;  1ZAD A;  1IDG A;  1LXG A;  1QKE A;  3FEV A;  4HQP F;  1HAA A;  4DO8 A;  1FFJ A;  1F94 A;  5DZ5 A;  1CDR A;  1LXH A;  2UWR A;  1IJC A;  3PLC A;  1G6M A;  1NXB A;  1DRS A;  3BT1 U;  1TFS A;  1W6B A;  1JBD A;  1UG4 A;  1B41 B;  1F8U B; 
#chains in the Genus database with same CATH topology
 1M9Z A;  2MUP A;  2BTX A;  2H64 B;  1CTX A;  3EVS C;  3VTS A;  1RGJ A;  1IDI A;  2FD6 U;  1IDL A;  2GOO C;  1ABT A;  2H7Z B;  3ERA A;  4RUD A;  2MJ4 A;  2H8U A;  1MAH F;  1CXN A;  2MFA A;  4KSN A;  4AEA A;  1REW C;  1ERG A;  1COD A;  1I02 A;  1IQ9 A;  1CVO A;  3KFD I;  2QJB C;  1LSI A;  5DU1 A;  4EY8 B;  2LCR A;  1CRF A;  1ONJ A;  2UX2 A;  1BXP A;  1CDT A;  2QC1 A;  1QM7 A;  5IMT D;  3QB4 B;  1ES7 B;  1KU6 B;  4P7U A;  3NH7 A;  5EBX A;  1KC4 A;  1S4Y A;  2MJ0 A;  1KXI A;  1HC9 A;  2J8B A;  1CCQ A;  2H5F A;  2JVE A;  1NEA A;  1VB0 A;  1LJZ A;  2L03 A;  2CDX A;  1CDS A;  1TXA A;  1H0J A;  2OFS A;  2N99 A;  2H62 C;  1KTZ B;  1KS6 A;  3EBX A;  2MHY A;  2CTX A;  5IMY C;  1BTE A;  2MJY A;  1XT3 A;  2PJY B;  3BT2 U;  1L4W A;  1FSC A;  2H62 D;  4LFT A;  1FRA A;  1IDH A;  1HAJ A;  1NTN A;  2HLR A;  2VLW A;  1KL8 A;  4UY2 C;  2BHI A;  1PLO A;  3KFD E;  4BDT B;  2I9B E;  1CDQ A;  2JQP A;  2ERA A;  1KBS A;  2QJA C;  1CHV S;  1IK8 A;  1FAS A;  2ABX A;  2X8B B;  1IKC A;  1COE A;  1NYS A;  1ERA A;  4OM5 A;  1HC9 B;  1NYU A;  1MR6 A;  4XJJ A;  1TGX A;  4BIK B;  1CRE A;  1QKD A;  1V6P A;  2CRT A;  1TXB A;  1NTX A;  2QJ9 C;  1KFH A;  1FSS B;  1KBT A;  2GOO B;  1JGK A;  1FF4 A;  1KBA A;  6EBX A;  1CXO A;  2HLQ A;  3HH7 A;  3NDS A;  1CB9 A;  1LX5 B;  2H64 C;  1YWH A;  3U74 U;  4FAO C;  5DO6 A;  3U73 U;  1NOR A;  2CCX A;  3LAQ U;  1HOY A;  4ZQY A;  2H7Z A;  2L5S A;  1RL5 A;  4FAO E;  2K3G A;  2NBT A;  2PJY C;  4OM4 A;  1JE9 A;  2LA1 A;  2MUO A;  2CRS A;  3NEQ A;  4QTI U;  4IYE A;  1ZAD A;  1IDG A;  1LXG A;  1QKE A;  3FEV A;  4HQP F;  1HAA A;  4DO8 A;  1FFJ A;  1F94 A;  5DZ5 A;  1CDR A;  1LXH A;  2UWR A;  1IJC A;  3PLC A;  1G6M A;  1NXB A;  1DRS A;  3BT1 U;  1TFS A;  1W6B A;  1JBD A;  1UG4 A;  1B41 B;  1F8U B; 
#chains in the Genus database with same CATH homology
 1M9Z A;  2MUP A;  2BTX A;  2H64 B;  1CTX A;  3EVS C;  3VTS A;  1RGJ A;  1IDI A;  2FD6 U;  1IDL A;  2GOO C;  1ABT A;  2H7Z B;  3ERA A;  4RUD A;  2MJ4 A;  2H8U A;  1MAH F;  1CXN A;  2MFA A;  4KSN A;  4AEA A;  1REW C;  1ERG A;  1COD A;  1I02 A;  1IQ9 A;  1CVO A;  3KFD I;  2QJB C;  1LSI A;  5DU1 A;  4EY8 B;  2LCR A;  1CRF A;  1ONJ A;  2UX2 A;  1BXP A;  1CDT A;  2QC1 A;  1QM7 A;  5IMT D;  3QB4 B;  1ES7 B;  1KU6 B;  4P7U A;  3NH7 A;  5EBX A;  1KC4 A;  1S4Y A;  2MJ0 A;  1KXI A;  1HC9 A;  2J8B A;  1CCQ A;  2H5F A;  2JVE A;  1NEA A;  1VB0 A;  1LJZ A;  2L03 A;  2CDX A;  1CDS A;  1TXA A;  1H0J A;  2OFS A;  2N99 A;  2H62 C;  1KTZ B;  1KS6 A;  3EBX A;  2MHY A;  2CTX A;  5IMY C;  1BTE A;  2MJY A;  1XT3 A;  2PJY B;  3BT2 U;  1L4W A;  1FSC A;  2H62 D;  4LFT A;  1FRA A;  1IDH A;  1HAJ A;  1NTN A;  2HLR A;  2VLW A;  1KL8 A;  4UY2 C;  2BHI A;  1PLO A;  3KFD E;  4BDT B;  2I9B E;  1CDQ A;  2JQP A;  2ERA A;  1KBS A;  2QJA C;  1CHV S;  1IK8 A;  1FAS A;  2ABX A;  2X8B B;  1IKC A;  1COE A;  1NYS A;  1ERA A;  4OM5 A;  1HC9 B;  1NYU A;  1MR6 A;  4XJJ A;  1TGX A;  4BIK B;  1CRE A;  1QKD A;  1V6P A;  2CRT A;  1TXB A;  1NTX A;  2QJ9 C;  1KFH A;  1FSS B;  1KBT A;  2GOO B;  1JGK A;  1FF4 A;  1KBA A;  6EBX A;  1CXO A;  2HLQ A;  3HH7 A;  3NDS A;  1CB9 A;  1LX5 B;  2H64 C;  1YWH A;  3U74 U;  4FAO C;  5DO6 A;  3U73 U;  1NOR A;  2CCX A;  3LAQ U;  1HOY A;  4ZQY A;  2H7Z A;  2L5S A;  1RL5 A;  4FAO E;  2K3G A;  2NBT A;  2PJY C;  4OM4 A;  1JE9 A;  2LA1 A;  2MUO A;  2CRS A;  3NEQ A;  4QTI U;  4IYE A;  1ZAD A;  1IDG A;  1LXG A;  1QKE A;  3FEV A;  4HQP F;  1HAA A;  4DO8 A;  1FFJ A;  1F94 A;  5DZ5 A;  1CDR A;  1LXH A;  2UWR A;  1IJC A;  3PLC A;  1G6M A;  1NXB A;  1DRS A;  3BT1 U;  1TFS A;  1W6B A;  1JBD A;  1UG4 A;  1B41 B;  1F8U B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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