1YWHA

Crystal structure of urokinase plasminogen activator receptor
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
279
structure length
268
Chain Sequence
LRCMQCKTNGDCRVEECALGQDLCRTTIVRLWEEGEELELVEKSCTHSEKTNRTLSYRTGLKITSLTEVVCGLDLCNQGNSGRSRYLECISCGSSDMSCERGRHQSLQCRSPEEQCLDVVTHWIQRPKDDRHLRGCGYLPGCPGSNGFHNNDTFHFLKCCNTTKCNEGPILELENLPQNGRQCYSCKGQSTHGCSSEETFLIDCRGPMNQCLVATGTHEPKNQSYMVRGCATASMCQHAHLGDAFSMNHIDVSCCTKSGCNHPDLDVQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase receptor
source organism Homo sapiens
publication title Crystal structure of the human urokinase plasminogen activator receptor bound to an antagonist peptide
pubmed doi rcsb
molecule keywords Urokinase plasminogen activator surface receptor
total genus 52
structure length 268
sequence length 279
chains with identical sequence C, E, G, I, K, M, O
ec nomenclature
pdb deposition date 2005-02-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00021 UPAR_LY6 u-PAR/Ly-6 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 1ywhA01
2.10.60.10 Mainly Beta Ribbon CD59 CD59 1ywhA03
2.10.60.10 Mainly Beta Ribbon CD59 CD59 1ywhA02
5IMTD 1COEA 1CREA 2QC1A 2FD6U 1BTEA 3BT2U 3PLCA 4OM4A 1F94A 1MR6A 1V6PA 1NYSA 1TXAA 4BIKB 4XJJA 1KC4A 3U73U 1FASA 2MUOA 1NTXA 1CDTA 1ZADA 2L03A 4QTIU 5DU1A 4ZQYA 1QM7A 1HC9A 2MJYA 2CRTA 4FAOE 1BXPA 1PLOA 2HLRA 1RGJA 3VTSA 1FSSB 2HLQA 1F8UB 1KBTA 1HAJA 3KFDE 1HAAA 2UWRA 1TFSA 1KL8A 3HH7A 4OM5A 3NEQA 3KFDI 2H7ZA 2BHIA 2N99A 4BDTB 1CHVS 2QJ9C 1QKDA 1MAHF 5IMYC 1LX5B 2QJAC 2H62C 1NYUA 1LJZA 1DRSA 1NXBA 4LFTA 2LCRA 2H64C 1YWHA 1KFHA 1KTZB 2H5FA 2L5SA 2MFAA 4P7UA 2OFSA 2PJYC 1KBAA 2MHYA 4FAOC 1H0JA 1CCQA 1XT3A 1B41B 1CXOA 1IDIA 1L4WA 1JGKA 2GOOC 2MUPA 2JVEA 1IQ9A 1LSIA 1G6MA 1NEAA 2CRSA 1CTXA 4IYEA 4DO8A 2BTXA 2K3GA 1CDQA 1IK8A 1FSCA 2CCXA 3NDSA 1ABTA 2H62D 1IDLA 1VB0A 1TGXA 1IJCA 2H64B 1KS6A 4UY2C 2UX2A 1M9ZA 1CXNA 2I9BE 1ES7B 5DO6A 2PJYB 1IDGA 1NORA 1KXIA 4EY8B 1S4YA 1HC9B 2H8UA 2NBTA 1FFJA 1KU6B 3EBXA 6EBXA 2GOOB 2X8BB 1CRFA 2MJ4A 2LA1A 2ERAA 1NTNA 3FEVA 1ERGA 2MJ0A 3QB4B 1UG4A 5EBXA 2QJBC 1CDRA 2CDXA 2CTXA 1LXHA 1JE9A 1HOYA 1W6BA 1I02A 1CB9A 1ERAA 1FF4A 1CDSA 3EVSC 2ABXA 1CVOA 4HQPF 1TXBA 1IKCA 1FRAA 3U74U 1ONJA 2H7ZB 1JBDA 2J8BA 3BT1U 4RUDA 3LAQU 1CODA 1LXGA 2JQPA 1REWC 5DZ5A 1IDHA 1KBSA 3ERAA 4AEAA 2VLWA 3NH7A 1QKEA 1RL5A
chains in the Genus database with same CATH superfamily
5IMTD 1COEA 1CREA 2QC1A 2FD6U 1BTEA 3BT2U 3PLCA 4OM4A 1F94A 1MR6A 1V6PA 1NYSA 1TXAA 4BIKB 4XJJA 1KC4A 3U73U 1FASA 2MUOA 1NTXA 1CDTA 1ZADA 2L03A 4QTIU 5DU1A 4ZQYA 1QM7A 1HC9A 2MJYA 2CRTA 4FAOE 1BXPA 1PLOA 2HLRA 1RGJA 3VTSA 1FSSB 2HLQA 1F8UB 1KBTA 1HAJA 3KFDE 1HAAA 2UWRA 1TFSA 1KL8A 3HH7A 4OM5A 3NEQA 3KFDI 2H7ZA 2BHIA 2N99A 4BDTB 1CHVS 2QJ9C 1QKDA 1MAHF 5IMYC 1LX5B 2QJAC 2H62C 1NYUA 1LJZA 1DRSA 1NXBA 4LFTA 2LCRA 2H64C 1YWHA 1KFHA 1KTZB 2H5FA 2L5SA 2MFAA 4P7UA 2OFSA 2PJYC 1KBAA 2MHYA 4FAOC 1H0JA 1CCQA 1XT3A 1B41B 1CXOA 1IDIA 1L4WA 1JGKA 2GOOC 2MUPA 2JVEA 1IQ9A 1LSIA 1G6MA 1NEAA 2CRSA 1CTXA 4IYEA 4DO8A 2BTXA 2K3GA 1CDQA 1IK8A 1FSCA 2CCXA 3NDSA 1ABTA 2H62D 1IDLA 1VB0A 1TGXA 1IJCA 2H64B 1KS6A 4UY2C 2UX2A 1M9ZA 1CXNA 2I9BE 1ES7B 5DO6A 2PJYB 1IDGA 1NORA 1KXIA 4EY8B 1S4YA 1HC9B 2H8UA 2NBTA 1FFJA 1KU6B 3EBXA 6EBXA 2GOOB 2X8BB 1CRFA 2MJ4A 2LA1A 2ERAA 1NTNA 3FEVA 1ERGA 2MJ0A 3QB4B 1UG4A 5EBXA 2QJBC 1CDRA 2CDXA 2CTXA 1LXHA 1JE9A 4KSNA 1W6BA 1HOYA 1I02A 1CB9A 1ERAA 1FF4A 1CDSA 3EVSC 2ABXA 1CVOA 4HQPF 1TXBA 1IKCA 1FRAA 3U74U 1ONJA 2H7ZB 1JBDA 2J8BA 3BT1U 4RUDA 3LAQU 1CODA 1LXGA 2JQPA 1REWC 5DZ5A 1IDHA 1KBSA 3ERAA 4AEAA 2VLWA 3NH7A 1QKEA 1RL5A
chains in the Genus database with same CATH topology
5IMTD 1COEA 1CREA 2QC1A 2FD6U 1BTEA 3BT2U 3PLCA 4OM4A 1F94A 1MR6A 1V6PA 1NYSA 1TXAA 4BIKB 4XJJA 1KC4A 3U73U 1FASA 2MUOA 1NTXA 1CDTA 1ZADA 2L03A 4QTIU 5DU1A 4ZQYA 1QM7A 1HC9A 2MJYA 2CRTA 4FAOE 1BXPA 1PLOA 2HLRA 1RGJA 3VTSA 1FSSB 2HLQA 1F8UB 1KBTA 1HAJA 3KFDE 1HAAA 2UWRA 1TFSA 1KL8A 3HH7A 4OM5A 3NEQA 3KFDI 2H7ZA 2BHIA 2N99A 4BDTB 1CHVS 2QJ9C 1QKDA 1MAHF 5IMYC 1LX5B 2QJAC 2H62C 1NYUA 1LJZA 1DRSA 1NXBA 4LFTA 2LCRA 2H64C 1YWHA 1KFHA 1KTZB 2H5FA 2L5SA 2MFAA 4P7UA 2OFSA 2PJYC 1KBAA 2MHYA 4FAOC 1H0JA 1CCQA 1XT3A 1B41B 1CXOA 1IDIA 1L4WA 1JGKA 2GOOC 2MUPA 2JVEA 1IQ9A 1LSIA 1G6MA 1NEAA 2CRSA 1CTXA 4IYEA 4DO8A 2BTXA 2K3GA 1CDQA 1IK8A 1FSCA 2CCXA 3NDSA 1ABTA 2H62D 1IDLA 1VB0A 1TGXA 1IJCA 2H64B 1KS6A 4UY2C 2UX2A 1M9ZA 1CXNA 2I9BE 1ES7B 5DO6A 2PJYB 1IDGA 1NORA 1KXIA 4EY8B 1S4YA 1HC9B 2H8UA 2NBTA 1FFJA 1KU6B 3EBXA 6EBXA 2GOOB 2X8BB 1CRFA 2MJ4A 2LA1A 2ERAA 1NTNA 3FEVA 1ERGA 2MJ0A 3QB4B 1UG4A 5EBXA 2QJBC 1CDRA 2CDXA 2CTXA 1LXHA 1JE9A 4KSNA 1W6BA 1HOYA 1I02A 1CB9A 1ERAA 1FF4A 1CDSA 3EVSC 2ABXA 1CVOA 4HQPF 1TXBA 1IKCA 1FRAA 3U74U 1ONJA 2H7ZB 1JBDA 2J8BA 3BT1U 4RUDA 3LAQU 1CODA 1LXGA 2JQPA 1REWC 5DZ5A 1IDHA 1KBSA 3ERAA 4AEAA 2VLWA 3NH7A 1QKEA 1RL5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IMT D;  1COE A;  1CRE A;  2QC1 A;  2FD6 U;  1BTE A;  3BT2 U;  3PLC A;  4OM4 A;  1F94 A;  1MR6 A;  1V6P A;  1NYS A;  1TXA A;  4BIK B;  4XJJ A;  1KC4 A;  3U73 U;  1FAS A;  2MUO A;  1NTX A;  1CDT A;  1ZAD A;  2L03 A;  4QTI U;  5DU1 A;  4ZQY A;  1QM7 A;  1HC9 A;  2MJY A;  2CRT A;  4FAO E;  1BXP A;  1PLO A;  2HLR A;  1RGJ A;  3VTS A;  1FSS B;  2HLQ A;  1F8U B;  1KBT A;  1HAJ A;  3KFD E;  1HAA A;  2UWR A;  1TFS A;  1KL8 A;  3HH7 A;  4OM5 A;  3NEQ A;  3KFD I;  2H7Z A;  2BHI A;  2N99 A;  4BDT B;  1CHV S;  2QJ9 C;  1QKD A;  1MAH F;  5IMY C;  1LX5 B;  2QJA C;  2H62 C;  1NYU A;  1LJZ A;  1DRS A;  1NXB A;  4LFT A;  2LCR A;  2H64 C;  1YWH A;  1KFH A;  1KTZ B;  2H5F A;  2L5S A;  2MFA A;  4P7U A;  2OFS A;  2PJY C;  1KBA A;  2MHY A;  4FAO C;  1H0J A;  1CCQ A;  1XT3 A;  1B41 B;  1CXO A;  1IDI A;  1L4W A;  1JGK A;  2GOO C;  2MUP A;  2JVE A;  1IQ9 A;  1LSI A;  1G6M A;  1NEA A;  2CRS A;  1CTX A;  4IYE A;  4DO8 A;  2BTX A;  2K3G A;  1CDQ A;  1IK8 A;  1FSC A;  2CCX A;  3NDS A;  1ABT A;  2H62 D;  1IDL A;  1VB0 A;  1TGX A;  1IJC A;  2H64 B;  1KS6 A;  4UY2 C;  2UX2 A;  1M9Z A;  1CXN A;  2I9B E;  1ES7 B;  5DO6 A;  2PJY B;  1IDG A;  1NOR A;  1KXI A;  4EY8 B;  1S4Y A;  1HC9 B;  2H8U A;  2NBT A;  1FFJ A;  1KU6 B;  3EBX A;  6EBX A;  2GOO B;  2X8B B;  1CRF A;  2MJ4 A;  2LA1 A;  2ERA A;  1NTN A;  3FEV A;  1ERG A;  2MJ0 A;  3QB4 B;  1UG4 A;  5EBX A;  2QJB C;  1CDR A;  2CDX A;  2CTX A;  1LXH A;  1JE9 A;  1HOY A;  1W6B A;  1I02 A;  1CB9 A;  1ERA A;  1FF4 A;  1CDS A;  3EVS C;  2ABX A;  1CVO A;  4HQP F;  1TXB A;  1IKC A;  1FRA A;  3U74 U;  1ONJ A;  2H7Z B;  1JBD A;  2J8B A;  3BT1 U;  4RUD A;  3LAQ U;  1COD A;  1LXG A;  2JQP A;  1REW C;  5DZ5 A;  1IDH A;  1KBS A;  3ERA A;  4AEA A;  2VLW A;  3NH7 A;  1QKE A;  1RL5 A; 
#chains in the Genus database with same CATH topology
 5IMT D;  1COE A;  1CRE A;  2QC1 A;  2FD6 U;  1BTE A;  3BT2 U;  3PLC A;  4OM4 A;  1F94 A;  1MR6 A;  1V6P A;  1NYS A;  1TXA A;  4BIK B;  4XJJ A;  1KC4 A;  3U73 U;  1FAS A;  2MUO A;  1NTX A;  1CDT A;  1ZAD A;  2L03 A;  4QTI U;  5DU1 A;  4ZQY A;  1QM7 A;  1HC9 A;  2MJY A;  2CRT A;  4FAO E;  1BXP A;  1PLO A;  2HLR A;  1RGJ A;  3VTS A;  1FSS B;  2HLQ A;  1F8U B;  1KBT A;  1HAJ A;  3KFD E;  1HAA A;  2UWR A;  1TFS A;  1KL8 A;  3HH7 A;  4OM5 A;  3NEQ A;  3KFD I;  2H7Z A;  2BHI A;  2N99 A;  4BDT B;  1CHV S;  2QJ9 C;  1QKD A;  1MAH F;  5IMY C;  1LX5 B;  2QJA C;  2H62 C;  1NYU A;  1LJZ A;  1DRS A;  1NXB A;  4LFT A;  2LCR A;  2H64 C;  1YWH A;  1KFH A;  1KTZ B;  2H5F A;  2L5S A;  2MFA A;  4P7U A;  2OFS A;  2PJY C;  1KBA A;  2MHY A;  4FAO C;  1H0J A;  1CCQ A;  1XT3 A;  1B41 B;  1CXO A;  1IDI A;  1L4W A;  1JGK A;  2GOO C;  2MUP A;  2JVE A;  1IQ9 A;  1LSI A;  1G6M A;  1NEA A;  2CRS A;  1CTX A;  4IYE A;  4DO8 A;  2BTX A;  2K3G A;  1CDQ A;  1IK8 A;  1FSC A;  2CCX A;  3NDS A;  1ABT A;  2H62 D;  1IDL A;  1VB0 A;  1TGX A;  1IJC A;  2H64 B;  1KS6 A;  4UY2 C;  2UX2 A;  1M9Z A;  1CXN A;  2I9B E;  1ES7 B;  5DO6 A;  2PJY B;  1IDG A;  1NOR A;  1KXI A;  4EY8 B;  1S4Y A;  1HC9 B;  2H8U A;  2NBT A;  1FFJ A;  1KU6 B;  3EBX A;  6EBX A;  2GOO B;  2X8B B;  1CRF A;  2MJ4 A;  2LA1 A;  2ERA A;  1NTN A;  3FEV A;  1ERG A;  2MJ0 A;  3QB4 B;  1UG4 A;  5EBX A;  2QJB C;  1CDR A;  2CDX A;  2CTX A;  1LXH A;  1JE9 A;  4KSN A;  1W6B A;  1HOY A;  1I02 A;  1CB9 A;  1ERA A;  1FF4 A;  1CDS A;  3EVS C;  2ABX A;  1CVO A;  4HQP F;  1TXB A;  1IKC A;  1FRA A;  3U74 U;  1ONJ A;  2H7Z B;  1JBD A;  2J8B A;  3BT1 U;  4RUD A;  3LAQ U;  1COD A;  1LXG A;  2JQP A;  1REW C;  5DZ5 A;  1IDH A;  1KBS A;  3ERA A;  4AEA A;  2VLW A;  3NH7 A;  1QKE A;  1RL5 A; 
#chains in the Genus database with same CATH homology
 5IMT D;  1COE A;  1CRE A;  2QC1 A;  2FD6 U;  1BTE A;  3BT2 U;  3PLC A;  4OM4 A;  1F94 A;  1MR6 A;  1V6P A;  1NYS A;  1TXA A;  4BIK B;  4XJJ A;  1KC4 A;  3U73 U;  1FAS A;  2MUO A;  1NTX A;  1CDT A;  1ZAD A;  2L03 A;  4QTI U;  5DU1 A;  4ZQY A;  1QM7 A;  1HC9 A;  2MJY A;  2CRT A;  4FAO E;  1BXP A;  1PLO A;  2HLR A;  1RGJ A;  3VTS A;  1FSS B;  2HLQ A;  1F8U B;  1KBT A;  1HAJ A;  3KFD E;  1HAA A;  2UWR A;  1TFS A;  1KL8 A;  3HH7 A;  4OM5 A;  3NEQ A;  3KFD I;  2H7Z A;  2BHI A;  2N99 A;  4BDT B;  1CHV S;  2QJ9 C;  1QKD A;  1MAH F;  5IMY C;  1LX5 B;  2QJA C;  2H62 C;  1NYU A;  1LJZ A;  1DRS A;  1NXB A;  4LFT A;  2LCR A;  2H64 C;  1YWH A;  1KFH A;  1KTZ B;  2H5F A;  2L5S A;  2MFA A;  4P7U A;  2OFS A;  2PJY C;  1KBA A;  2MHY A;  4FAO C;  1H0J A;  1CCQ A;  1XT3 A;  1B41 B;  1CXO A;  1IDI A;  1L4W A;  1JGK A;  2GOO C;  2MUP A;  2JVE A;  1IQ9 A;  1LSI A;  1G6M A;  1NEA A;  2CRS A;  1CTX A;  4IYE A;  4DO8 A;  2BTX A;  2K3G A;  1CDQ A;  1IK8 A;  1FSC A;  2CCX A;  3NDS A;  1ABT A;  2H62 D;  1IDL A;  1VB0 A;  1TGX A;  1IJC A;  2H64 B;  1KS6 A;  4UY2 C;  2UX2 A;  1M9Z A;  1CXN A;  2I9B E;  1ES7 B;  5DO6 A;  2PJY B;  1IDG A;  1NOR A;  1KXI A;  4EY8 B;  1S4Y A;  1HC9 B;  2H8U A;  2NBT A;  1FFJ A;  1KU6 B;  3EBX A;  6EBX A;  2GOO B;  2X8B B;  1CRF A;  2MJ4 A;  2LA1 A;  2ERA A;  1NTN A;  3FEV A;  1ERG A;  2MJ0 A;  3QB4 B;  1UG4 A;  5EBX A;  2QJB C;  1CDR A;  2CDX A;  2CTX A;  1LXH A;  1JE9 A;  4KSN A;  1W6B A;  1HOY A;  1I02 A;  1CB9 A;  1ERA A;  1FF4 A;  1CDS A;  3EVS C;  2ABX A;  1CVO A;  4HQP F;  1TXB A;  1IKC A;  1FRA A;  3U74 U;  1ONJ A;  2H7Z B;  1JBD A;  2J8B A;  3BT1 U;  4RUD A;  3LAQ U;  1COD A;  1LXG A;  2JQP A;  1REW C;  5DZ5 A;  1IDH A;  1KBS A;  3ERA A;  4AEA A;  2VLW A;  3NH7 A;  1QKE A;  1RL5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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