2GOOC

Ternary complex of bmp-2 bound to bmpr-ia-ecd and actrii-ecd
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
92
structure length
92
Chain Sequence
TQECLFFNANWERDRTNQTGVEPCYGDKDKRRHCFATWKNISGSIEIVKQGCWLDDINCYDRTDCIEKKDSPEVYFCCCEGNMCNEKFSYFP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the ternary signaling complex of a TGF-beta superfamily member.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Bone morphogenetic protein 2
total genus 21
structure length 92
sequence length 92
chains with identical sequence F
ec nomenclature ec 2.7.11.30: Receptor protein serine/threonine kinase.
pdb deposition date 2006-04-13
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 2gooC00
1MAHF 2PJYB 2QC1A 1NTNA 2GOOB 2MHYA 1TXBA 5DU1A 1CDSA 1QKEA 4QTIU 3BT1U 4EY8B 1FFJA 1KS6A 3VTSA 1KTZB 3ERAA 2X8BB 3NH7A 4AEAA 3BT2U 1B41B 1IJCA 2BTXA 1LXHA 3FEVA 2VLWA 1FSSB 1IKCA 1TXAA 5EBXA 3QB4B 1LJZA 1JE9A 2L03A 1LXGA 4XJJA 2H5FA 1L4WA 1COEA 1HAJA 1NXBA 2QJBC 4HQPF 2MFAA 1IDIA 1LSIA 1CODA 2PJYC 1ERGA 1CDRA 1JBDA 1TFSA 2JVEA 2GOOC 1QKDA 2ABXA 1TGXA 2LA1A 1H0JA 2QJ9C 1XT3A 4P7UA 1KXIA 1ERAA 3PLCA 1W6BA 4FAOC 1F94A 2HLQA 1LX5B 1IDLA 3EVSC 1KBAA 1BTEA 1CRFA 1KL8A 1NEAA 1NYSA 4FAOE 1IDGA 1VB0A 3NDSA 2CRSA 1IDHA 2CCXA 1CDTA 1CXNA 1NTXA 1ABTA 2CTXA 1ONJA 2MJYA 1REWC 2LCRA 1CCQA 1ZADA 1F8UB 2H64B 1KBTA 1JGKA 3KFDE 1KFHA 1NORA 4BDTB 1IK8A 1BXPA 1M9ZA 1QM7A 4RUDA 4OM5A 1KBSA 5DZ5A 2CDXA 5IMYC 1CB9A 4BIKB 2UWRA 2UX2A 1HC9A 2H62D 2MUPA 1CVOA 1NYUA 1UG4A 1CHVS 4OM4A 1CREA 4UY2C 1I02A 1HOYA 3HH7A 2H7ZA 2H62C 4DO8A 5IMTD 2CRTA 2QJAC 1IQ9A 2NBTA 2N99A 1FSCA 4LFTA 1RGJA 1G6MA 2H8UA 2H64C 2MUOA 4ZQYA 1FRAA 1CTXA 1V6PA 2MJ0A 1HC9B 1MR6A 1FASA 3KFDI 1RL5A 1CXOA 1YWHA 6EBXA 3LAQU 2OFSA 1ES7B 2JQPA 1CDQA 2MJ4A 2H7ZB 3U74U 1KU6B 1FF4A 3U73U 2FD6U 2BHIA 2J8BA 1KC4A 2L5SA 3EBXA 2ERAA 2HLRA 3NEQA 1DRSA 1PLOA 1S4YA 4IYEA 1HAAA 2I9BE 5DO6A 2K3GA
chains in the Genus database with same CATH superfamily
1MAHF 2PJYB 2QC1A 1NTNA 2GOOB 2MHYA 1TXBA 5DU1A 1CDSA 1QKEA 4QTIU 3BT1U 4EY8B 1FFJA 1KS6A 3VTSA 1KTZB 3ERAA 2X8BB 3NH7A 4AEAA 3BT2U 1B41B 1IJCA 2BTXA 1LXHA 3FEVA 2VLWA 1FSSB 1IKCA 1TXAA 5EBXA 3QB4B 1LJZA 1JE9A 2L03A 1LXGA 4XJJA 2H5FA 1L4WA 1COEA 1HAJA 1NXBA 2QJBC 4HQPF 2MFAA 1IDIA 1LSIA 1CODA 2PJYC 1ERGA 1CDRA 1JBDA 1TFSA 2JVEA 2GOOC 1QKDA 2ABXA 1TGXA 2LA1A 1H0JA 2QJ9C 1XT3A 4P7UA 1KXIA 1ERAA 3PLCA 1W6BA 4FAOC 1F94A 2HLQA 1LX5B 1IDLA 3EVSC 1KBAA 1BTEA 1CRFA 1KL8A 1NEAA 1NYSA 4FAOE 1IDGA 1VB0A 3NDSA 2CRSA 1IDHA 2CCXA 1CDTA 1CXNA 1NTXA 1ABTA 2CTXA 1ONJA 2MJYA 1REWC 2LCRA 1CCQA 1ZADA 1F8UB 2H64B 1KBTA 1JGKA 3KFDE 1KFHA 1NORA 4BDTB 1IK8A 1BXPA 1M9ZA 1QM7A 4RUDA 4OM5A 1KBSA 5DZ5A 2CDXA 5IMYC 1CB9A 4BIKB 2UWRA 2UX2A 1HC9A 2H62D 2MUPA 1CVOA 1NYUA 1UG4A 1CHVS 4OM4A 1CREA 4UY2C 1I02A 1HOYA 3HH7A 2H7ZA 2H62C 4DO8A 5IMTD 2CRTA 2QJAC 1IQ9A 2NBTA 2N99A 1FSCA 4LFTA 1RGJA 1G6MA 2H8UA 2H64C 2MUOA 4ZQYA 1FRAA 1CTXA 1V6PA 2MJ0A 1HC9B 1MR6A 1FASA 3KFDI 4KSNA 1RL5A 1CXOA 1YWHA 6EBXA 3LAQU 2OFSA 1ES7B 2JQPA 1CDQA 2MJ4A 2H7ZB 3U74U 1KU6B 1FF4A 3U73U 2FD6U 2BHIA 2J8BA 1KC4A 2L5SA 3EBXA 2ERAA 2HLRA 3NEQA 1DRSA 1PLOA 1S4YA 4IYEA 1HAAA 2I9BE 5DO6A 2K3GA
chains in the Genus database with same CATH topology
1MAHF 2PJYB 2QC1A 1NTNA 2GOOB 2MHYA 1TXBA 5DU1A 1CDSA 1QKEA 4QTIU 3BT1U 4EY8B 1FFJA 1KS6A 3VTSA 1KTZB 3ERAA 2X8BB 3NH7A 4AEAA 3BT2U 1B41B 1IJCA 2BTXA 1LXHA 3FEVA 2VLWA 1FSSB 1IKCA 1TXAA 5EBXA 3QB4B 1LJZA 1JE9A 2L03A 1LXGA 4XJJA 2H5FA 1L4WA 1COEA 1HAJA 1NXBA 2QJBC 4HQPF 2MFAA 1IDIA 1LSIA 1CODA 2PJYC 1ERGA 1CDRA 1JBDA 1TFSA 2JVEA 2GOOC 1QKDA 2ABXA 1TGXA 2LA1A 1H0JA 2QJ9C 1XT3A 4P7UA 1KXIA 1ERAA 3PLCA 1W6BA 4FAOC 1F94A 2HLQA 1LX5B 1IDLA 3EVSC 1KBAA 1BTEA 1CRFA 1KL8A 1NEAA 1NYSA 4FAOE 1IDGA 1VB0A 3NDSA 2CRSA 1IDHA 2CCXA 1CDTA 1CXNA 1NTXA 1ABTA 2CTXA 1ONJA 2MJYA 1REWC 2LCRA 1CCQA 1ZADA 1F8UB 2H64B 1KBTA 1JGKA 3KFDE 1KFHA 1NORA 4BDTB 1IK8A 1BXPA 1M9ZA 1QM7A 4RUDA 4OM5A 1KBSA 5DZ5A 2CDXA 5IMYC 1CB9A 4BIKB 2UWRA 2UX2A 1HC9A 2H62D 2MUPA 1CVOA 1NYUA 1UG4A 1CHVS 4OM4A 1CREA 4UY2C 1I02A 1HOYA 3HH7A 2H7ZA 2H62C 4DO8A 5IMTD 2CRTA 2QJAC 1IQ9A 2NBTA 2N99A 1FSCA 4LFTA 1RGJA 1G6MA 2H8UA 2H64C 2MUOA 4ZQYA 1FRAA 1CTXA 1V6PA 2MJ0A 1HC9B 1MR6A 1FASA 3KFDI 4KSNA 1RL5A 1CXOA 1YWHA 6EBXA 3LAQU 2OFSA 1ES7B 2JQPA 1CDQA 2MJ4A 2H7ZB 3U74U 1KU6B 1FF4A 3U73U 2FD6U 2BHIA 2J8BA 1KC4A 2L5SA 3EBXA 2ERAA 2HLRA 3NEQA 1DRSA 1PLOA 1S4YA 4IYEA 1HAAA 2I9BE 5DO6A 2K3GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MAH F;  2PJY B;  2QC1 A;  1NTN A;  2GOO B;  2MHY A;  1TXB A;  5DU1 A;  1CDS A;  1QKE A;  4QTI U;  3BT1 U;  4EY8 B;  1FFJ A;  1KS6 A;  3VTS A;  1KTZ B;  3ERA A;  2X8B B;  3NH7 A;  4AEA A;  3BT2 U;  1B41 B;  1IJC A;  2BTX A;  1LXH A;  3FEV A;  2VLW A;  1FSS B;  1IKC A;  1TXA A;  5EBX A;  3QB4 B;  1LJZ A;  1JE9 A;  2L03 A;  1LXG A;  4XJJ A;  2H5F A;  1L4W A;  1COE A;  1HAJ A;  1NXB A;  2QJB C;  4HQP F;  2MFA A;  1IDI A;  1LSI A;  1COD A;  2PJY C;  1ERG A;  1CDR A;  1JBD A;  1TFS A;  2JVE A;  2GOO C;  1QKD A;  2ABX A;  1TGX A;  2LA1 A;  1H0J A;  2QJ9 C;  1XT3 A;  4P7U A;  1KXI A;  1ERA A;  3PLC A;  1W6B A;  4FAO C;  1F94 A;  2HLQ A;  1LX5 B;  1IDL A;  3EVS C;  1KBA A;  1BTE A;  1CRF A;  1KL8 A;  1NEA A;  1NYS A;  4FAO E;  1IDG A;  1VB0 A;  3NDS A;  2CRS A;  1IDH A;  2CCX A;  1CDT A;  1CXN A;  1NTX A;  1ABT A;  2CTX A;  1ONJ A;  2MJY A;  1REW C;  2LCR A;  1CCQ A;  1ZAD A;  1F8U B;  2H64 B;  1KBT A;  1JGK A;  3KFD E;  1KFH A;  1NOR A;  4BDT B;  1IK8 A;  1BXP A;  1M9Z A;  1QM7 A;  4RUD A;  4OM5 A;  1KBS A;  5DZ5 A;  2CDX A;  5IMY C;  1CB9 A;  4BIK B;  2UWR A;  2UX2 A;  1HC9 A;  2H62 D;  2MUP A;  1CVO A;  1NYU A;  1UG4 A;  1CHV S;  4OM4 A;  1CRE A;  4UY2 C;  1I02 A;  1HOY A;  3HH7 A;  2H7Z A;  2H62 C;  4DO8 A;  5IMT D;  2CRT A;  2QJA C;  1IQ9 A;  2NBT A;  2N99 A;  1FSC A;  4LFT A;  1RGJ A;  1G6M A;  2H8U A;  2H64 C;  2MUO A;  4ZQY A;  1FRA A;  1CTX A;  1V6P A;  2MJ0 A;  1HC9 B;  1MR6 A;  1FAS A;  3KFD I;  1RL5 A;  1CXO A;  1YWH A;  6EBX A;  3LAQ U;  2OFS A;  1ES7 B;  2JQP A;  1CDQ A;  2MJ4 A;  2H7Z B;  3U74 U;  1KU6 B;  1FF4 A;  3U73 U;  2FD6 U;  2BHI A;  2J8B A;  1KC4 A;  2L5S A;  3EBX A;  2ERA A;  2HLR A;  3NEQ A;  1DRS A;  1PLO A;  1S4Y A;  4IYE A;  1HAA A;  2I9B E;  5DO6 A;  2K3G A; 
#chains in the Genus database with same CATH topology
 1MAH F;  2PJY B;  2QC1 A;  1NTN A;  2GOO B;  2MHY A;  1TXB A;  5DU1 A;  1CDS A;  1QKE A;  4QTI U;  3BT1 U;  4EY8 B;  1FFJ A;  1KS6 A;  3VTS A;  1KTZ B;  3ERA A;  2X8B B;  3NH7 A;  4AEA A;  3BT2 U;  1B41 B;  1IJC A;  2BTX A;  1LXH A;  3FEV A;  2VLW A;  1FSS B;  1IKC A;  1TXA A;  5EBX A;  3QB4 B;  1LJZ A;  1JE9 A;  2L03 A;  1LXG A;  4XJJ A;  2H5F A;  1L4W A;  1COE A;  1HAJ A;  1NXB A;  2QJB C;  4HQP F;  2MFA A;  1IDI A;  1LSI A;  1COD A;  2PJY C;  1ERG A;  1CDR A;  1JBD A;  1TFS A;  2JVE A;  2GOO C;  1QKD A;  2ABX A;  1TGX A;  2LA1 A;  1H0J A;  2QJ9 C;  1XT3 A;  4P7U A;  1KXI A;  1ERA A;  3PLC A;  1W6B A;  4FAO C;  1F94 A;  2HLQ A;  1LX5 B;  1IDL A;  3EVS C;  1KBA A;  1BTE A;  1CRF A;  1KL8 A;  1NEA A;  1NYS A;  4FAO E;  1IDG A;  1VB0 A;  3NDS A;  2CRS A;  1IDH A;  2CCX A;  1CDT A;  1CXN A;  1NTX A;  1ABT A;  2CTX A;  1ONJ A;  2MJY A;  1REW C;  2LCR A;  1CCQ A;  1ZAD A;  1F8U B;  2H64 B;  1KBT A;  1JGK A;  3KFD E;  1KFH A;  1NOR A;  4BDT B;  1IK8 A;  1BXP A;  1M9Z A;  1QM7 A;  4RUD A;  4OM5 A;  1KBS A;  5DZ5 A;  2CDX A;  5IMY C;  1CB9 A;  4BIK B;  2UWR A;  2UX2 A;  1HC9 A;  2H62 D;  2MUP A;  1CVO A;  1NYU A;  1UG4 A;  1CHV S;  4OM4 A;  1CRE A;  4UY2 C;  1I02 A;  1HOY A;  3HH7 A;  2H7Z A;  2H62 C;  4DO8 A;  5IMT D;  2CRT A;  2QJA C;  1IQ9 A;  2NBT A;  2N99 A;  1FSC A;  4LFT A;  1RGJ A;  1G6M A;  2H8U A;  2H64 C;  2MUO A;  4ZQY A;  1FRA A;  1CTX A;  1V6P A;  2MJ0 A;  1HC9 B;  1MR6 A;  1FAS A;  3KFD I;  4KSN A;  1RL5 A;  1CXO A;  1YWH A;  6EBX A;  3LAQ U;  2OFS A;  1ES7 B;  2JQP A;  1CDQ A;  2MJ4 A;  2H7Z B;  3U74 U;  1KU6 B;  1FF4 A;  3U73 U;  2FD6 U;  2BHI A;  2J8B A;  1KC4 A;  2L5S A;  3EBX A;  2ERA A;  2HLR A;  3NEQ A;  1DRS A;  1PLO A;  1S4Y A;  4IYE A;  1HAA A;  2I9B E;  5DO6 A;  2K3G A; 
#chains in the Genus database with same CATH homology
 1MAH F;  2PJY B;  2QC1 A;  1NTN A;  2GOO B;  2MHY A;  1TXB A;  5DU1 A;  1CDS A;  1QKE A;  4QTI U;  3BT1 U;  4EY8 B;  1FFJ A;  1KS6 A;  3VTS A;  1KTZ B;  3ERA A;  2X8B B;  3NH7 A;  4AEA A;  3BT2 U;  1B41 B;  1IJC A;  2BTX A;  1LXH A;  3FEV A;  2VLW A;  1FSS B;  1IKC A;  1TXA A;  5EBX A;  3QB4 B;  1LJZ A;  1JE9 A;  2L03 A;  1LXG A;  4XJJ A;  2H5F A;  1L4W A;  1COE A;  1HAJ A;  1NXB A;  2QJB C;  4HQP F;  2MFA A;  1IDI A;  1LSI A;  1COD A;  2PJY C;  1ERG A;  1CDR A;  1JBD A;  1TFS A;  2JVE A;  2GOO C;  1QKD A;  2ABX A;  1TGX A;  2LA1 A;  1H0J A;  2QJ9 C;  1XT3 A;  4P7U A;  1KXI A;  1ERA A;  3PLC A;  1W6B A;  4FAO C;  1F94 A;  2HLQ A;  1LX5 B;  1IDL A;  3EVS C;  1KBA A;  1BTE A;  1CRF A;  1KL8 A;  1NEA A;  1NYS A;  4FAO E;  1IDG A;  1VB0 A;  3NDS A;  2CRS A;  1IDH A;  2CCX A;  1CDT A;  1CXN A;  1NTX A;  1ABT A;  2CTX A;  1ONJ A;  2MJY A;  1REW C;  2LCR A;  1CCQ A;  1ZAD A;  1F8U B;  2H64 B;  1KBT A;  1JGK A;  3KFD E;  1KFH A;  1NOR A;  4BDT B;  1IK8 A;  1BXP A;  1M9Z A;  1QM7 A;  4RUD A;  4OM5 A;  1KBS A;  5DZ5 A;  2CDX A;  5IMY C;  1CB9 A;  4BIK B;  2UWR A;  2UX2 A;  1HC9 A;  2H62 D;  2MUP A;  1CVO A;  1NYU A;  1UG4 A;  1CHV S;  4OM4 A;  1CRE A;  4UY2 C;  1I02 A;  1HOY A;  3HH7 A;  2H7Z A;  2H62 C;  4DO8 A;  5IMT D;  2CRT A;  2QJA C;  1IQ9 A;  2NBT A;  2N99 A;  1FSC A;  4LFT A;  1RGJ A;  1G6M A;  2H8U A;  2H64 C;  2MUO A;  4ZQY A;  1FRA A;  1CTX A;  1V6P A;  2MJ0 A;  1HC9 B;  1MR6 A;  1FAS A;  3KFD I;  4KSN A;  1RL5 A;  1CXO A;  1YWH A;  6EBX A;  3LAQ U;  2OFS A;  1ES7 B;  2JQP A;  1CDQ A;  2MJ4 A;  2H7Z B;  3U74 U;  1KU6 B;  1FF4 A;  3U73 U;  2FD6 U;  2BHI A;  2J8B A;  1KC4 A;  2L5S A;  3EBX A;  2ERA A;  2HLR A;  3NEQ A;  1DRS A;  1PLO A;  1S4Y A;  4IYE A;  1HAA A;  2I9B E;  5DO6 A;  2K3G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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