2ABXA

The crystal structure of alpha-bungarotoxin at 2.5 angstroms resolution. relation to solution structure and binding to acetylcholine receptor
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
74
structure length
74
Chain Sequence
IVCHTTATIPSSAVTCPPGENLCYRKMWCDAFCSSRGKVVELGCAATCPSKKPYEEVTCCSTDKCNHPPKRQPG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Postsynaptic neurotoxin
source organism Bungarus multicinctus
publication title The crystal structure of alpha-bungarotoxin at 2.5 A resolution: relation to solution structure and binding to acetylcholine receptor.
pubmed doi rcsb
molecule keywords ALPHA-BUNGAROTOXIN
total genus 5
structure length 74
sequence length 74
chains with identical sequence B
ec nomenclature
pdb deposition date 1986-02-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00087 Toxin_TOLIP Snake toxin and toxin-like protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 2abxA00
1LXGA 4UY2C 1B41B 2X8BB 1IDIA 1KTZB 2MJ0A 1RGJA 5DZ5A 1CDTA 3PLCA 5DU1A 1CB9A 1NYSA 1IDHA 4RUDA 1FFJA 1KXIA 1QKDA 2MUPA 1S4YA 1BTEA 1FSSB 5EBXA 1KS6A 2K3GA 2QJAC 1LSIA 1MR6A 2H7ZA 2H8UA 3U74U 1JGKA 1HOYA 2CDXA 1KBSA 1CXNA 1CVOA 1YWHA 1LX5B 3VTSA 2GOOB 1ZADA 3EVSC 1I02A 2UWRA 2LA1A 1FRAA 2H64C 2FD6U 3NDSA 1RL5A 2I9BE 4OM5A 4EY8B 1CTXA 1COEA 1MAHF 1F8UB 1KU6B 1TXAA 2J8BA 1NXBA 2L03A 1IDGA 1ABTA 2ABXA 2MJYA 3BT2U 2CCXA 2QJ9C 1CHVS 3KFDE 3EBXA 1IKCA 1G6MA 4FAOC 2NBTA 3BT1U 4ZQYA 1LXHA 4QTIU 3U73U 2MFAA 3ERAA 4AEAA 2HLQA 1UG4A 2PJYC 2H5FA 2L5SA 1KL8A 1HC9B 2CTXA 1CRFA 1NEAA 1XT3A 4DO8A 1KBTA 1TGXA 2N99A 1M9ZA 2ERAA 2MUOA 1JBDA 1V6PA 2OFSA 1FF4A 1NYUA 2H64B 1NORA 1CODA 1F94A 2JQPA 1VB0A 1HAAA 1KFHA 1CDRA 3LAQU 4BIKB 2HLRA 2CRSA 4FAOE 1ONJA 4P7UA 1H0JA 4BDTB 1JE9A 2LCRA 2VLWA 1L4WA 1ES7B 1IJCA 2JVEA 1FASA 1ERAA 2BHIA 2H62D 3FEVA 3HH7A 3NEQA 4IYEA 1HAJA 1QM7A 2QJBC 2H7ZB 2PJYB 3NH7A 1KBAA 4OM4A 2H62C 1NTNA 4LFTA 2QC1A 1DRSA 1NTXA 1TXBA 2MJ4A 1IK8A 1TFSA 1ERGA 1CXOA 1IQ9A 1IDLA 2MHYA 1CREA 4HQPF 2UX2A 1REWC 1HC9A 3KFDI 4XJJA 6EBXA 2GOOC 5IMYC 2CRTA 1LJZA 3QB4B 1FSCA 1W6BA 5IMTD 1KC4A 5DO6A 1CCQA 1QKEA 1PLOA 1CDSA 2BTXA 1CDQA 1BXPA
chains in the Genus database with same CATH superfamily
1LXGA 4UY2C 1B41B 2X8BB 1IDIA 1KTZB 2MJ0A 1RGJA 5DZ5A 1CDTA 3PLCA 5DU1A 1CB9A 1NYSA 1IDHA 4RUDA 1FFJA 1KXIA 1QKDA 2MUPA 1S4YA 1BTEA 1FSSB 4KSNA 5EBXA 1KS6A 2K3GA 2QJAC 1LSIA 1MR6A 2H7ZA 2H8UA 3U74U 1JGKA 1HOYA 2CDXA 1KBSA 1CXNA 1CVOA 1YWHA 1LX5B 3VTSA 2GOOB 1ZADA 3EVSC 1I02A 2UWRA 2LA1A 1FRAA 2H64C 2FD6U 3NDSA 1RL5A 2I9BE 4OM5A 4EY8B 1CTXA 1COEA 1MAHF 1F8UB 1KU6B 1TXAA 2J8BA 1NXBA 2L03A 1IDGA 1ABTA 2ABXA 2MJYA 3BT2U 2CCXA 2QJ9C 1CHVS 3KFDE 3EBXA 1IKCA 1G6MA 4FAOC 2NBTA 3BT1U 4ZQYA 1LXHA 4QTIU 3U73U 2MFAA 3ERAA 4AEAA 2HLQA 1UG4A 2PJYC 2H5FA 2L5SA 1KL8A 1HC9B 2CTXA 1CRFA 1NEAA 1XT3A 4DO8A 1KBTA 1TGXA 2N99A 1M9ZA 2ERAA 2MUOA 1JBDA 1V6PA 2OFSA 1FF4A 1NYUA 2H64B 1NORA 1CODA 1F94A 2JQPA 1VB0A 1HAAA 1KFHA 1CDRA 3LAQU 4BIKB 2HLRA 2CRSA 4FAOE 1ONJA 4P7UA 1H0JA 4BDTB 1JE9A 2LCRA 2VLWA 1L4WA 1ES7B 1IJCA 2JVEA 1FASA 1ERAA 2BHIA 2H62D 3FEVA 3HH7A 3NEQA 4IYEA 1HAJA 1QM7A 2QJBC 2H7ZB 2PJYB 3NH7A 1KBAA 4OM4A 2H62C 1NTNA 4LFTA 2QC1A 1DRSA 1NTXA 1TXBA 2MJ4A 1IK8A 1TFSA 1ERGA 1CXOA 1IQ9A 1IDLA 2MHYA 1CREA 4HQPF 2UX2A 1REWC 1HC9A 3KFDI 4XJJA 6EBXA 2GOOC 5IMYC 2CRTA 1LJZA 3QB4B 1FSCA 1W6BA 5IMTD 1KC4A 5DO6A 1CCQA 1QKEA 1PLOA 1CDSA 2BTXA 1CDQA 1BXPA
chains in the Genus database with same CATH topology
1LXGA 4UY2C 1B41B 2X8BB 1IDIA 1KTZB 2MJ0A 1RGJA 5DZ5A 1CDTA 3PLCA 5DU1A 1CB9A 1NYSA 1IDHA 4RUDA 1FFJA 1KXIA 1QKDA 2MUPA 1S4YA 1BTEA 1FSSB 4KSNA 5EBXA 1KS6A 2K3GA 2QJAC 1LSIA 1MR6A 2H7ZA 2H8UA 3U74U 1JGKA 1HOYA 2CDXA 1KBSA 1CXNA 1CVOA 1YWHA 1LX5B 3VTSA 2GOOB 1ZADA 3EVSC 1I02A 2UWRA 2LA1A 1FRAA 2H64C 2FD6U 3NDSA 1RL5A 2I9BE 4OM5A 4EY8B 1CTXA 1COEA 1MAHF 1F8UB 1KU6B 1TXAA 2J8BA 1NXBA 2L03A 1IDGA 1ABTA 2ABXA 2MJYA 3BT2U 2CCXA 2QJ9C 1CHVS 3KFDE 3EBXA 1IKCA 1G6MA 4FAOC 2NBTA 3BT1U 4ZQYA 1LXHA 4QTIU 3U73U 2MFAA 3ERAA 4AEAA 2HLQA 1UG4A 2PJYC 2H5FA 2L5SA 1KL8A 1HC9B 2CTXA 1CRFA 1NEAA 1XT3A 4DO8A 1KBTA 1TGXA 2N99A 1M9ZA 2ERAA 2MUOA 1JBDA 1V6PA 2OFSA 1FF4A 1NYUA 2H64B 1NORA 1CODA 1F94A 2JQPA 1VB0A 1HAAA 1KFHA 1CDRA 3LAQU 4BIKB 2HLRA 2CRSA 4FAOE 1ONJA 4P7UA 1H0JA 4BDTB 1JE9A 2LCRA 2VLWA 1L4WA 1ES7B 1IJCA 2JVEA 1FASA 1ERAA 2BHIA 2H62D 3FEVA 3HH7A 3NEQA 4IYEA 1HAJA 1QM7A 2QJBC 2H7ZB 2PJYB 3NH7A 1KBAA 4OM4A 2H62C 1NTNA 4LFTA 2QC1A 1DRSA 1NTXA 1TXBA 2MJ4A 1IK8A 1TFSA 1ERGA 1CXOA 1IQ9A 1IDLA 2MHYA 1CREA 4HQPF 2UX2A 1REWC 1HC9A 3KFDI 4XJJA 6EBXA 2GOOC 5IMYC 2CRTA 1LJZA 3QB4B 1FSCA 1W6BA 5IMTD 1KC4A 5DO6A 1CCQA 1QKEA 1PLOA 1CDSA 2BTXA 1CDQA 1BXPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LXG A;  4UY2 C;  1B41 B;  2X8B B;  1IDI A;  1KTZ B;  2MJ0 A;  1RGJ A;  5DZ5 A;  1CDT A;  3PLC A;  5DU1 A;  1CB9 A;  1NYS A;  1IDH A;  4RUD A;  1FFJ A;  1KXI A;  1QKD A;  2MUP A;  1S4Y A;  1BTE A;  1FSS B;  5EBX A;  1KS6 A;  2K3G A;  2QJA C;  1LSI A;  1MR6 A;  2H7Z A;  2H8U A;  3U74 U;  1JGK A;  1HOY A;  2CDX A;  1KBS A;  1CXN A;  1CVO A;  1YWH A;  1LX5 B;  3VTS A;  2GOO B;  1ZAD A;  3EVS C;  1I02 A;  2UWR A;  2LA1 A;  1FRA A;  2H64 C;  2FD6 U;  3NDS A;  1RL5 A;  2I9B E;  4OM5 A;  4EY8 B;  1CTX A;  1COE A;  1MAH F;  1F8U B;  1KU6 B;  1TXA A;  2J8B A;  1NXB A;  2L03 A;  1IDG A;  1ABT A;  2ABX A;  2MJY A;  3BT2 U;  2CCX A;  2QJ9 C;  1CHV S;  3KFD E;  3EBX A;  1IKC A;  1G6M A;  4FAO C;  2NBT A;  3BT1 U;  4ZQY A;  1LXH A;  4QTI U;  3U73 U;  2MFA A;  3ERA A;  4AEA A;  2HLQ A;  1UG4 A;  2PJY C;  2H5F A;  2L5S A;  1KL8 A;  1HC9 B;  2CTX A;  1CRF A;  1NEA A;  1XT3 A;  4DO8 A;  1KBT A;  1TGX A;  2N99 A;  1M9Z A;  2ERA A;  2MUO A;  1JBD A;  1V6P A;  2OFS A;  1FF4 A;  1NYU A;  2H64 B;  1NOR A;  1COD A;  1F94 A;  2JQP A;  1VB0 A;  1HAA A;  1KFH A;  1CDR A;  3LAQ U;  4BIK B;  2HLR A;  2CRS A;  4FAO E;  1ONJ A;  4P7U A;  1H0J A;  4BDT B;  1JE9 A;  2LCR A;  2VLW A;  1L4W A;  1ES7 B;  1IJC A;  2JVE A;  1FAS A;  1ERA A;  2BHI A;  2H62 D;  3FEV A;  3HH7 A;  3NEQ A;  4IYE A;  1HAJ A;  1QM7 A;  2QJB C;  2H7Z B;  2PJY B;  3NH7 A;  1KBA A;  4OM4 A;  2H62 C;  1NTN A;  4LFT A;  2QC1 A;  1DRS A;  1NTX A;  1TXB A;  2MJ4 A;  1IK8 A;  1TFS A;  1ERG A;  1CXO A;  1IQ9 A;  1IDL A;  2MHY A;  1CRE A;  4HQP F;  2UX2 A;  1REW C;  1HC9 A;  3KFD I;  4XJJ A;  6EBX A;  2GOO C;  5IMY C;  2CRT A;  1LJZ A;  3QB4 B;  1FSC A;  1W6B A;  5IMT D;  1KC4 A;  5DO6 A;  1CCQ A;  1QKE A;  1PLO A;  1CDS A;  2BTX A;  1CDQ A;  1BXP A; 
#chains in the Genus database with same CATH topology
 1LXG A;  4UY2 C;  1B41 B;  2X8B B;  1IDI A;  1KTZ B;  2MJ0 A;  1RGJ A;  5DZ5 A;  1CDT A;  3PLC A;  5DU1 A;  1CB9 A;  1NYS A;  1IDH A;  4RUD A;  1FFJ A;  1KXI A;  1QKD A;  2MUP A;  1S4Y A;  1BTE A;  1FSS B;  4KSN A;  5EBX A;  1KS6 A;  2K3G A;  2QJA C;  1LSI A;  1MR6 A;  2H7Z A;  2H8U A;  3U74 U;  1JGK A;  1HOY A;  2CDX A;  1KBS A;  1CXN A;  1CVO A;  1YWH A;  1LX5 B;  3VTS A;  2GOO B;  1ZAD A;  3EVS C;  1I02 A;  2UWR A;  2LA1 A;  1FRA A;  2H64 C;  2FD6 U;  3NDS A;  1RL5 A;  2I9B E;  4OM5 A;  4EY8 B;  1CTX A;  1COE A;  1MAH F;  1F8U B;  1KU6 B;  1TXA A;  2J8B A;  1NXB A;  2L03 A;  1IDG A;  1ABT A;  2ABX A;  2MJY A;  3BT2 U;  2CCX A;  2QJ9 C;  1CHV S;  3KFD E;  3EBX A;  1IKC A;  1G6M A;  4FAO C;  2NBT A;  3BT1 U;  4ZQY A;  1LXH A;  4QTI U;  3U73 U;  2MFA A;  3ERA A;  4AEA A;  2HLQ A;  1UG4 A;  2PJY C;  2H5F A;  2L5S A;  1KL8 A;  1HC9 B;  2CTX A;  1CRF A;  1NEA A;  1XT3 A;  4DO8 A;  1KBT A;  1TGX A;  2N99 A;  1M9Z A;  2ERA A;  2MUO A;  1JBD A;  1V6P A;  2OFS A;  1FF4 A;  1NYU A;  2H64 B;  1NOR A;  1COD A;  1F94 A;  2JQP A;  1VB0 A;  1HAA A;  1KFH A;  1CDR A;  3LAQ U;  4BIK B;  2HLR A;  2CRS A;  4FAO E;  1ONJ A;  4P7U A;  1H0J A;  4BDT B;  1JE9 A;  2LCR A;  2VLW A;  1L4W A;  1ES7 B;  1IJC A;  2JVE A;  1FAS A;  1ERA A;  2BHI A;  2H62 D;  3FEV A;  3HH7 A;  3NEQ A;  4IYE A;  1HAJ A;  1QM7 A;  2QJB C;  2H7Z B;  2PJY B;  3NH7 A;  1KBA A;  4OM4 A;  2H62 C;  1NTN A;  4LFT A;  2QC1 A;  1DRS A;  1NTX A;  1TXB A;  2MJ4 A;  1IK8 A;  1TFS A;  1ERG A;  1CXO A;  1IQ9 A;  1IDL A;  2MHY A;  1CRE A;  4HQP F;  2UX2 A;  1REW C;  1HC9 A;  3KFD I;  4XJJ A;  6EBX A;  2GOO C;  5IMY C;  2CRT A;  1LJZ A;  3QB4 B;  1FSC A;  1W6B A;  5IMT D;  1KC4 A;  5DO6 A;  1CCQ A;  1QKE A;  1PLO A;  1CDS A;  2BTX A;  1CDQ A;  1BXP A; 
#chains in the Genus database with same CATH homology
 1LXG A;  4UY2 C;  1B41 B;  2X8B B;  1IDI A;  1KTZ B;  2MJ0 A;  1RGJ A;  5DZ5 A;  1CDT A;  3PLC A;  5DU1 A;  1CB9 A;  1NYS A;  1IDH A;  4RUD A;  1FFJ A;  1KXI A;  1QKD A;  2MUP A;  1S4Y A;  1BTE A;  1FSS B;  4KSN A;  5EBX A;  1KS6 A;  2K3G A;  2QJA C;  1LSI A;  1MR6 A;  2H7Z A;  2H8U A;  3U74 U;  1JGK A;  1HOY A;  2CDX A;  1KBS A;  1CXN A;  1CVO A;  1YWH A;  1LX5 B;  3VTS A;  2GOO B;  1ZAD A;  3EVS C;  1I02 A;  2UWR A;  2LA1 A;  1FRA A;  2H64 C;  2FD6 U;  3NDS A;  1RL5 A;  2I9B E;  4OM5 A;  4EY8 B;  1CTX A;  1COE A;  1MAH F;  1F8U B;  1KU6 B;  1TXA A;  2J8B A;  1NXB A;  2L03 A;  1IDG A;  1ABT A;  2ABX A;  2MJY A;  3BT2 U;  2CCX A;  2QJ9 C;  1CHV S;  3KFD E;  3EBX A;  1IKC A;  1G6M A;  4FAO C;  2NBT A;  3BT1 U;  4ZQY A;  1LXH A;  4QTI U;  3U73 U;  2MFA A;  3ERA A;  4AEA A;  2HLQ A;  1UG4 A;  2PJY C;  2H5F A;  2L5S A;  1KL8 A;  1HC9 B;  2CTX A;  1CRF A;  1NEA A;  1XT3 A;  4DO8 A;  1KBT A;  1TGX A;  2N99 A;  1M9Z A;  2ERA A;  2MUO A;  1JBD A;  1V6P A;  2OFS A;  1FF4 A;  1NYU A;  2H64 B;  1NOR A;  1COD A;  1F94 A;  2JQP A;  1VB0 A;  1HAA A;  1KFH A;  1CDR A;  3LAQ U;  4BIK B;  2HLR A;  2CRS A;  4FAO E;  1ONJ A;  4P7U A;  1H0J A;  4BDT B;  1JE9 A;  2LCR A;  2VLW A;  1L4W A;  1ES7 B;  1IJC A;  2JVE A;  1FAS A;  1ERA A;  2BHI A;  2H62 D;  3FEV A;  3HH7 A;  3NEQ A;  4IYE A;  1HAJ A;  1QM7 A;  2QJB C;  2H7Z B;  2PJY B;  3NH7 A;  1KBA A;  4OM4 A;  2H62 C;  1NTN A;  4LFT A;  2QC1 A;  1DRS A;  1NTX A;  1TXB A;  2MJ4 A;  1IK8 A;  1TFS A;  1ERG A;  1CXO A;  1IQ9 A;  1IDL A;  2MHY A;  1CRE A;  4HQP F;  2UX2 A;  1REW C;  1HC9 A;  3KFD I;  4XJJ A;  6EBX A;  2GOO C;  5IMY C;  2CRT A;  1LJZ A;  3QB4 B;  1FSC A;  1W6B A;  5IMT D;  1KC4 A;  5DO6 A;  1CCQ A;  1QKE A;  1PLO A;  1CDS A;  2BTX A;  1CDQ A;  1BXP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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