2H62D

Crystal structure of a ternary ligand-receptor complex of bmp-2
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
93
structure length
93
Chain Sequence
AETRECIYYNANWELERTNQSGLERCEGEQDKRLHCYASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hormone/growth factor
source organism Homo sapiens
publication title A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor.
pubmed doi rcsb
molecule keywords Bone morphogenetic protein 2
total genus 21
structure length 93
sequence length 93
ec nomenclature ec 2.7.11.30: Receptor protein serine/threonine kinase.
pdb deposition date 2006-05-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 2h62D00
2MUOA 1ERAA 1FSSB 2H8UA 1V6PA 1JGKA 2ABXA 1HC9B 1KU6B 1MR6A 1RL5A 3KFDI 1TXBA 1KC4A 3PLCA 4FAOE 1M9ZA 3NH7A 1JBDA 1F8UB 2HLRA 2UWRA 1H0JA 2VLWA 3BT1U 1IKCA 1KBAA 4RUDA 1TXAA 1XT3A 1REWC 1CHVS 4IYEA 1ZADA 1CDSA 1CRFA 2L5SA 3FEVA 5EBXA 1NYSA 1KBSA 1FF4A 3VTSA 1CDTA 3LAQU 2OFSA 3U73U 1W6BA 1NXBA 2CDXA 2H7ZA 2H62C 1LJZA 1B41B 1KFHA 1HC9A 3QB4B 1ES7B 2H5FA 4OM5A 1CXNA 2CRTA 1IDGA 1BXPA 4DO8A 4LFTA 1NTXA 4HQPF 4QTIU 1CODA 1IDHA 1IQ9A 2GOOC 2J8BA 1CCQA 1I02A 2PJYC 3NEQA 2LCRA 3EVSC 3BT2U 1IDLA 1FASA 5IMTD 2QJBC 2MUPA 4OM4A 4AEAA 1KBTA 1YWHA 1KTZB 1RGJA 3HH7A 1HAJA 2JVEA 6EBXA 4ZQYA 1LX5B 1CTXA 1NTNA 1CDRA 4BDTB 2MJYA 2CTXA 3ERAA 1F94A 1QKDA 1DRSA 2X8BB 4P7UA 2UX2A 3NDSA 2GOOB 1IJCA 2MHYA 1ABTA 1LXHA 2CCXA 4UY2C 2PJYB 1CREA 2FD6U 2QJ9C 1CB9A 1L4WA 5IMYC 1VB0A 2H62D 1HAAA 2LA1A 2L03A 2QC1A 1NEAA 2CRSA 2H64C 1TFSA 1QM7A 4FAOC 2MJ4A 5DZ5A 2NBTA 4XJJA 5DO6A 1FFJA 4EY8B 1S4YA 2MFAA 1LXGA 1QKEA 1PLOA 1G6MA 1ERGA 1FRAA 2N99A 1MAHF 2K3GA 1KL8A 1NORA 3EBXA 1BTEA 2ERAA 1CXOA 2MJ0A 3U74U 2QJAC 3KFDE 1CDQA 1HOYA 1CVOA 1UG4A 1KS6A 1NYUA 2H64B 2I9BE 4BIKB 1COEA 2BTXA 1JE9A 1IK8A 1KXIA 1TGXA 2HLQA 5DU1A 1LSIA 2BHIA 1IDIA 1FSCA 1ONJA 2JQPA 2H7ZB
chains in the Genus database with same CATH superfamily
2MUOA 1ERAA 1FSSB 2H8UA 1V6PA 1JGKA 2ABXA 1HC9B 1KU6B 1MR6A 1RL5A 3KFDI 1TXBA 1KC4A 3PLCA 4FAOE 1M9ZA 3NH7A 1JBDA 1F8UB 2HLRA 2UWRA 1H0JA 2VLWA 3BT1U 1IKCA 1KBAA 4RUDA 1TXAA 1XT3A 1REWC 1CHVS 4IYEA 1ZADA 1CDSA 1CRFA 2L5SA 3FEVA 5EBXA 4KSNA 1NYSA 1KBSA 1FF4A 3VTSA 1CDTA 3LAQU 2OFSA 3U73U 1W6BA 1NXBA 2CDXA 2H7ZA 2H62C 1LJZA 1B41B 1KFHA 1HC9A 3QB4B 1ES7B 2H5FA 4OM5A 1CXNA 2CRTA 1IDGA 1BXPA 4DO8A 4LFTA 1NTXA 4HQPF 4QTIU 1CODA 1IDHA 1IQ9A 2GOOC 2J8BA 1CCQA 1I02A 2PJYC 3NEQA 2LCRA 3EVSC 3BT2U 1IDLA 1FASA 5IMTD 2QJBC 2MUPA 4OM4A 4AEAA 1KBTA 1YWHA 1KTZB 1RGJA 3HH7A 1HAJA 2JVEA 6EBXA 4ZQYA 1LX5B 1CTXA 1NTNA 1CDRA 4BDTB 2MJYA 2CTXA 3ERAA 1F94A 1QKDA 1DRSA 2X8BB 4P7UA 2UX2A 3NDSA 2GOOB 1IJCA 2MHYA 1ABTA 1LXHA 2CCXA 4UY2C 2PJYB 1CREA 2FD6U 2QJ9C 1CB9A 1L4WA 5IMYC 1VB0A 2H62D 1HAAA 2LA1A 2L03A 2QC1A 1NEAA 2CRSA 2H64C 1TFSA 1QM7A 4FAOC 2MJ4A 5DZ5A 2NBTA 4XJJA 5DO6A 1FFJA 4EY8B 1S4YA 2MFAA 1LXGA 1QKEA 1PLOA 1G6MA 1ERGA 1FRAA 2N99A 1MAHF 2K3GA 1KL8A 1NORA 3EBXA 1BTEA 2ERAA 1CXOA 2MJ0A 3U74U 2QJAC 3KFDE 1CDQA 1HOYA 1CVOA 1UG4A 1KS6A 1NYUA 2H64B 2I9BE 4BIKB 1COEA 2BTXA 1JE9A 1IK8A 1KXIA 1TGXA 2HLQA 5DU1A 1LSIA 2BHIA 1IDIA 1FSCA 1ONJA 2JQPA 2H7ZB
chains in the Genus database with same CATH topology
2MUOA 1ERAA 1FSSB 2H8UA 1V6PA 1JGKA 2ABXA 1HC9B 1KU6B 1MR6A 1RL5A 3KFDI 1TXBA 1KC4A 3PLCA 4FAOE 1M9ZA 3NH7A 1JBDA 1F8UB 2HLRA 2UWRA 1H0JA 2VLWA 3BT1U 1IKCA 1KBAA 4RUDA 1TXAA 1XT3A 1REWC 1CHVS 4IYEA 1ZADA 1CDSA 1CRFA 2L5SA 3FEVA 5EBXA 4KSNA 1NYSA 1KBSA 1FF4A 3VTSA 1CDTA 3LAQU 2OFSA 3U73U 1W6BA 1NXBA 2CDXA 2H7ZA 2H62C 1LJZA 1B41B 1KFHA 1HC9A 3QB4B 1ES7B 2H5FA 4OM5A 1CXNA 2CRTA 1IDGA 1BXPA 4DO8A 4LFTA 1NTXA 4HQPF 4QTIU 1CODA 1IDHA 1IQ9A 2GOOC 2J8BA 1CCQA 1I02A 2PJYC 3NEQA 2LCRA 3EVSC 3BT2U 1IDLA 1FASA 5IMTD 2QJBC 2MUPA 4OM4A 4AEAA 1KBTA 1YWHA 1KTZB 1RGJA 3HH7A 1HAJA 2JVEA 6EBXA 4ZQYA 1LX5B 1CTXA 1NTNA 1CDRA 4BDTB 2MJYA 2CTXA 3ERAA 1F94A 1QKDA 1DRSA 2X8BB 4P7UA 2UX2A 3NDSA 2GOOB 1IJCA 2MHYA 1ABTA 1LXHA 2CCXA 4UY2C 2PJYB 1CREA 2FD6U 2QJ9C 1CB9A 1L4WA 5IMYC 1VB0A 2H62D 1HAAA 2LA1A 2L03A 2QC1A 1NEAA 2CRSA 2H64C 1TFSA 1QM7A 4FAOC 2MJ4A 5DZ5A 2NBTA 4XJJA 5DO6A 1FFJA 4EY8B 1S4YA 2MFAA 1LXGA 1QKEA 1PLOA 1G6MA 1ERGA 1FRAA 2N99A 1MAHF 2K3GA 1KL8A 1NORA 3EBXA 1BTEA 2ERAA 1CXOA 2MJ0A 3U74U 2QJAC 3KFDE 1CDQA 1HOYA 1CVOA 1UG4A 1KS6A 1NYUA 2H64B 2I9BE 4BIKB 1COEA 2BTXA 1JE9A 1IK8A 1KXIA 1TGXA 2HLQA 5DU1A 1LSIA 2BHIA 1IDIA 1FSCA 1ONJA 2JQPA 2H7ZB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2MUO A;  1ERA A;  1FSS B;  2H8U A;  1V6P A;  1JGK A;  2ABX A;  1HC9 B;  1KU6 B;  1MR6 A;  1RL5 A;  3KFD I;  1TXB A;  1KC4 A;  3PLC A;  4FAO E;  1M9Z A;  3NH7 A;  1JBD A;  1F8U B;  2HLR A;  2UWR A;  1H0J A;  2VLW A;  3BT1 U;  1IKC A;  1KBA A;  4RUD A;  1TXA A;  1XT3 A;  1REW C;  1CHV S;  4IYE A;  1ZAD A;  1CDS A;  1CRF A;  2L5S A;  3FEV A;  5EBX A;  1NYS A;  1KBS A;  1FF4 A;  3VTS A;  1CDT A;  3LAQ U;  2OFS A;  3U73 U;  1W6B A;  1NXB A;  2CDX A;  2H7Z A;  2H62 C;  1LJZ A;  1B41 B;  1KFH A;  1HC9 A;  3QB4 B;  1ES7 B;  2H5F A;  4OM5 A;  1CXN A;  2CRT A;  1IDG A;  1BXP A;  4DO8 A;  4LFT A;  1NTX A;  4HQP F;  4QTI U;  1COD A;  1IDH A;  1IQ9 A;  2GOO C;  2J8B A;  1CCQ A;  1I02 A;  2PJY C;  3NEQ A;  2LCR A;  3EVS C;  3BT2 U;  1IDL A;  1FAS A;  5IMT D;  2QJB C;  2MUP A;  4OM4 A;  4AEA A;  1KBT A;  1YWH A;  1KTZ B;  1RGJ A;  3HH7 A;  1HAJ A;  2JVE A;  6EBX A;  4ZQY A;  1LX5 B;  1CTX A;  1NTN A;  1CDR A;  4BDT B;  2MJY A;  2CTX A;  3ERA A;  1F94 A;  1QKD A;  1DRS A;  2X8B B;  4P7U A;  2UX2 A;  3NDS A;  2GOO B;  1IJC A;  2MHY A;  1ABT A;  1LXH A;  2CCX A;  4UY2 C;  2PJY B;  1CRE A;  2FD6 U;  2QJ9 C;  1CB9 A;  1L4W A;  5IMY C;  1VB0 A;  2H62 D;  1HAA A;  2LA1 A;  2L03 A;  2QC1 A;  1NEA A;  2CRS A;  2H64 C;  1TFS A;  1QM7 A;  4FAO C;  2MJ4 A;  5DZ5 A;  2NBT A;  4XJJ A;  5DO6 A;  1FFJ A;  4EY8 B;  1S4Y A;  2MFA A;  1LXG A;  1QKE A;  1PLO A;  1G6M A;  1ERG A;  1FRA A;  2N99 A;  1MAH F;  2K3G A;  1KL8 A;  1NOR A;  3EBX A;  1BTE A;  2ERA A;  1CXO A;  2MJ0 A;  3U74 U;  2QJA C;  3KFD E;  1CDQ A;  1HOY A;  1CVO A;  1UG4 A;  1KS6 A;  1NYU A;  2H64 B;  2I9B E;  4BIK B;  1COE A;  2BTX A;  1JE9 A;  1IK8 A;  1KXI A;  1TGX A;  2HLQ A;  5DU1 A;  1LSI A;  2BHI A;  1IDI A;  1FSC A;  1ONJ A;  2JQP A;  2H7Z B; 
#chains in the Genus database with same CATH topology
 2MUO A;  1ERA A;  1FSS B;  2H8U A;  1V6P A;  1JGK A;  2ABX A;  1HC9 B;  1KU6 B;  1MR6 A;  1RL5 A;  3KFD I;  1TXB A;  1KC4 A;  3PLC A;  4FAO E;  1M9Z A;  3NH7 A;  1JBD A;  1F8U B;  2HLR A;  2UWR A;  1H0J A;  2VLW A;  3BT1 U;  1IKC A;  1KBA A;  4RUD A;  1TXA A;  1XT3 A;  1REW C;  1CHV S;  4IYE A;  1ZAD A;  1CDS A;  1CRF A;  2L5S A;  3FEV A;  5EBX A;  4KSN A;  1NYS A;  1KBS A;  1FF4 A;  3VTS A;  1CDT A;  3LAQ U;  2OFS A;  3U73 U;  1W6B A;  1NXB A;  2CDX A;  2H7Z A;  2H62 C;  1LJZ A;  1B41 B;  1KFH A;  1HC9 A;  3QB4 B;  1ES7 B;  2H5F A;  4OM5 A;  1CXN A;  2CRT A;  1IDG A;  1BXP A;  4DO8 A;  4LFT A;  1NTX A;  4HQP F;  4QTI U;  1COD A;  1IDH A;  1IQ9 A;  2GOO C;  2J8B A;  1CCQ A;  1I02 A;  2PJY C;  3NEQ A;  2LCR A;  3EVS C;  3BT2 U;  1IDL A;  1FAS A;  5IMT D;  2QJB C;  2MUP A;  4OM4 A;  4AEA A;  1KBT A;  1YWH A;  1KTZ B;  1RGJ A;  3HH7 A;  1HAJ A;  2JVE A;  6EBX A;  4ZQY A;  1LX5 B;  1CTX A;  1NTN A;  1CDR A;  4BDT B;  2MJY A;  2CTX A;  3ERA A;  1F94 A;  1QKD A;  1DRS A;  2X8B B;  4P7U A;  2UX2 A;  3NDS A;  2GOO B;  1IJC A;  2MHY A;  1ABT A;  1LXH A;  2CCX A;  4UY2 C;  2PJY B;  1CRE A;  2FD6 U;  2QJ9 C;  1CB9 A;  1L4W A;  5IMY C;  1VB0 A;  2H62 D;  1HAA A;  2LA1 A;  2L03 A;  2QC1 A;  1NEA A;  2CRS A;  2H64 C;  1TFS A;  1QM7 A;  4FAO C;  2MJ4 A;  5DZ5 A;  2NBT A;  4XJJ A;  5DO6 A;  1FFJ A;  4EY8 B;  1S4Y A;  2MFA A;  1LXG A;  1QKE A;  1PLO A;  1G6M A;  1ERG A;  1FRA A;  2N99 A;  1MAH F;  2K3G A;  1KL8 A;  1NOR A;  3EBX A;  1BTE A;  2ERA A;  1CXO A;  2MJ0 A;  3U74 U;  2QJA C;  3KFD E;  1CDQ A;  1HOY A;  1CVO A;  1UG4 A;  1KS6 A;  1NYU A;  2H64 B;  2I9B E;  4BIK B;  1COE A;  2BTX A;  1JE9 A;  1IK8 A;  1KXI A;  1TGX A;  2HLQ A;  5DU1 A;  1LSI A;  2BHI A;  1IDI A;  1FSC A;  1ONJ A;  2JQP A;  2H7Z B; 
#chains in the Genus database with same CATH homology
 2MUO A;  1ERA A;  1FSS B;  2H8U A;  1V6P A;  1JGK A;  2ABX A;  1HC9 B;  1KU6 B;  1MR6 A;  1RL5 A;  3KFD I;  1TXB A;  1KC4 A;  3PLC A;  4FAO E;  1M9Z A;  3NH7 A;  1JBD A;  1F8U B;  2HLR A;  2UWR A;  1H0J A;  2VLW A;  3BT1 U;  1IKC A;  1KBA A;  4RUD A;  1TXA A;  1XT3 A;  1REW C;  1CHV S;  4IYE A;  1ZAD A;  1CDS A;  1CRF A;  2L5S A;  3FEV A;  5EBX A;  4KSN A;  1NYS A;  1KBS A;  1FF4 A;  3VTS A;  1CDT A;  3LAQ U;  2OFS A;  3U73 U;  1W6B A;  1NXB A;  2CDX A;  2H7Z A;  2H62 C;  1LJZ A;  1B41 B;  1KFH A;  1HC9 A;  3QB4 B;  1ES7 B;  2H5F A;  4OM5 A;  1CXN A;  2CRT A;  1IDG A;  1BXP A;  4DO8 A;  4LFT A;  1NTX A;  4HQP F;  4QTI U;  1COD A;  1IDH A;  1IQ9 A;  2GOO C;  2J8B A;  1CCQ A;  1I02 A;  2PJY C;  3NEQ A;  2LCR A;  3EVS C;  3BT2 U;  1IDL A;  1FAS A;  5IMT D;  2QJB C;  2MUP A;  4OM4 A;  4AEA A;  1KBT A;  1YWH A;  1KTZ B;  1RGJ A;  3HH7 A;  1HAJ A;  2JVE A;  6EBX A;  4ZQY A;  1LX5 B;  1CTX A;  1NTN A;  1CDR A;  4BDT B;  2MJY A;  2CTX A;  3ERA A;  1F94 A;  1QKD A;  1DRS A;  2X8B B;  4P7U A;  2UX2 A;  3NDS A;  2GOO B;  1IJC A;  2MHY A;  1ABT A;  1LXH A;  2CCX A;  4UY2 C;  2PJY B;  1CRE A;  2FD6 U;  2QJ9 C;  1CB9 A;  1L4W A;  5IMY C;  1VB0 A;  2H62 D;  1HAA A;  2LA1 A;  2L03 A;  2QC1 A;  1NEA A;  2CRS A;  2H64 C;  1TFS A;  1QM7 A;  4FAO C;  2MJ4 A;  5DZ5 A;  2NBT A;  4XJJ A;  5DO6 A;  1FFJ A;  4EY8 B;  1S4Y A;  2MFA A;  1LXG A;  1QKE A;  1PLO A;  1G6M A;  1ERG A;  1FRA A;  2N99 A;  1MAH F;  2K3G A;  1KL8 A;  1NOR A;  3EBX A;  1BTE A;  2ERA A;  1CXO A;  2MJ0 A;  3U74 U;  2QJA C;  3KFD E;  1CDQ A;  1HOY A;  1CVO A;  1UG4 A;  1KS6 A;  1NYU A;  2H64 B;  2I9B E;  4BIK B;  1COE A;  2BTX A;  1JE9 A;  1IK8 A;  1KXI A;  1TGX A;  2HLQ A;  5DU1 A;  1LSI A;  2BHI A;  1IDI A;  1FSC A;  1ONJ A;  2JQP A;  2H7Z B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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