2H7ZA

Crystal structure of irditoxin
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
75
structure length
75
Chain Sequence
QAVGPPYTLCFECNRMTSSDCSTALRCYRGSCYTLYRPDENCELKWAVKGCAETCPTAGPNERVKCCRSPRCNDD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
publication title Irditoxin, a novel covalently linked heterodimeric three-finger toxin with high taxon-specific neurotoxicity.
pubmed doi rcsb
molecule keywords Irditoxin subunit A
total genus 12
structure length 75
sequence length 75
ec nomenclature
pdb deposition date 2006-06-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00087 Toxin_TOLIP Snake toxin and toxin-like protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 2h7zA00
5EBXA 3PLCA 1JBDA 2GOOC 4FAOC 1XT3A 2L5SA 1IQ9A 3U73U 2NBTA 1FASA 1NYSA 4FAOE 3KFDE 1PLOA 2ABXA 1ONJA 1KTZB 1TGXA 6EBXA 4QTIU 1TXBA 2MUOA 2H5FA 2MUPA 4HQPF 3FEVA 1KS6A 1ES7B 5IMTD 1MAHF 1LXGA 1NTXA 1VB0A 1S4YA 1HAJA 1G6MA 1CXNA 4OM5A 1NXBA 1KBSA 1CXOA 2MJYA 2OFSA 2QJ9C 1CTXA 3NH7A 3BT2U 2CRSA 1QKEA 1CDQA 2H62D 3LAQU 4RUDA 1JGKA 1HOYA 2JVEA 1CB9A 1CODA 1FSCA 2H62C 2JQPA 2MJ4A 1JE9A 2N99A 2HLRA 5IMYC 4LFTA 1CRFA 1LX5B 2MJ0A 1F8UB 1H0JA 1MR6A 1KC4A 1BTEA 1IDLA 2LCRA 2VLWA 1COEA 2QC1A 2BHIA 2H7ZB 2CDXA 2LA1A 1IK8A 1ERGA 5DZ5A 4ZQYA 1IKCA 2HLQA 1RGJA 1I02A 1RL5A 2BTXA 1HC9B 3VTSA 1CCQA 1TXAA 2MFAA 2QJAC 1TFSA 1W6BA 4AEAA 2I9BE 2H8UA 2K3GA 1CDTA 4OM4A 2PJYB 1YWHA 1LXHA 3HH7A 1ERAA 4UY2C 1KXIA 4IYEA 1KL8A 1UG4A 1L4WA 2H64B 1FSSB 1CVOA 1KFHA 1DRSA 4BIKB 3U74U 2H64C 2H7ZA 1BXPA 1CDRA 1ABTA 1IDGA 1B41B 1ZADA 3ERAA 1FFJA 4P7UA 2J8BA 3KFDI 2CCXA 1HC9A 1CDSA 1CHVS 1REWC 1KBTA 1KBAA 1HAAA 2CRTA 3EBXA 1NEAA 4XJJA 2UWRA 3NEQA 4BDTB 5DO6A 1NYUA 1IJCA 3EVSC 3NDSA 1LJZA 1QM7A 2L03A 1QKDA 2QJBC 2UX2A 2CTXA 1IDHA 1NORA 4DO8A 1KU6B 1FRAA 3BT1U 1FF4A 2PJYC 2X8BB 2FD6U 5DU1A 1LSIA 3QB4B 1CREA 1IDIA 1NTNA 1F94A 2MHYA 2ERAA 1V6PA 1M9ZA 4EY8B 2GOOB
chains in the Genus database with same CATH superfamily
5EBXA 3PLCA 1JBDA 2GOOC 4FAOC 1XT3A 2L5SA 1IQ9A 3U73U 2NBTA 1FASA 1NYSA 4FAOE 3KFDE 1PLOA 2ABXA 1ONJA 1KTZB 1TGXA 6EBXA 4QTIU 1TXBA 2MUOA 2H5FA 4KSNA 2MUPA 4HQPF 3FEVA 1KS6A 1ES7B 5IMTD 1MAHF 1LXGA 1NTXA 1VB0A 1S4YA 1HAJA 1G6MA 1CXNA 4OM5A 1NXBA 1KBSA 1CXOA 2MJYA 2OFSA 2QJ9C 1CTXA 3NH7A 3BT2U 2CRSA 1QKEA 1CDQA 2H62D 3LAQU 4RUDA 1JGKA 1HOYA 2JVEA 1CB9A 1CODA 1FSCA 2H62C 2JQPA 2MJ4A 1JE9A 2N99A 2HLRA 5IMYC 4LFTA 1CRFA 1LX5B 2MJ0A 1F8UB 1H0JA 1MR6A 1KC4A 1BTEA 1IDLA 2LCRA 2VLWA 1COEA 2QC1A 2BHIA 2H7ZB 2CDXA 2LA1A 1IK8A 1ERGA 5DZ5A 4ZQYA 1IKCA 2HLQA 1RGJA 1I02A 1RL5A 2BTXA 1HC9B 3VTSA 1CCQA 1TXAA 2MFAA 2QJAC 1TFSA 1W6BA 4AEAA 2I9BE 2H8UA 2K3GA 1CDTA 4OM4A 2PJYB 1YWHA 1LXHA 3HH7A 1ERAA 4UY2C 1KXIA 4IYEA 1KL8A 1UG4A 1L4WA 2H64B 1FSSB 1CVOA 1KFHA 1DRSA 4BIKB 3U74U 2H64C 2H7ZA 1BXPA 1CDRA 1ABTA 1IDGA 1B41B 1ZADA 3ERAA 1FFJA 4P7UA 2J8BA 3KFDI 2CCXA 1HC9A 1CDSA 1CHVS 1REWC 1KBTA 1KBAA 1HAAA 2CRTA 3EBXA 1NEAA 4XJJA 2UWRA 3NEQA 4BDTB 5DO6A 1NYUA 1IJCA 3EVSC 3NDSA 1LJZA 1QM7A 2L03A 1QKDA 2QJBC 2UX2A 2CTXA 1IDHA 1NORA 4DO8A 1KU6B 1FRAA 3BT1U 1FF4A 2PJYC 2X8BB 2FD6U 5DU1A 1LSIA 3QB4B 1CREA 1IDIA 1NTNA 1F94A 2MHYA 2ERAA 1V6PA 1M9ZA 4EY8B 2GOOB
chains in the Genus database with same CATH topology
5EBXA 3PLCA 1JBDA 2GOOC 4FAOC 1XT3A 2L5SA 1IQ9A 3U73U 2NBTA 1FASA 1NYSA 4FAOE 3KFDE 1PLOA 2ABXA 1ONJA 1KTZB 1TGXA 6EBXA 4QTIU 1TXBA 2MUOA 2H5FA 4KSNA 2MUPA 4HQPF 3FEVA 1KS6A 1ES7B 5IMTD 1MAHF 1LXGA 1NTXA 1VB0A 1S4YA 1HAJA 1G6MA 1CXNA 4OM5A 1NXBA 1KBSA 1CXOA 2MJYA 2OFSA 2QJ9C 1CTXA 3NH7A 3BT2U 2CRSA 1QKEA 1CDQA 2H62D 3LAQU 4RUDA 1JGKA 1HOYA 2JVEA 1CB9A 1CODA 1FSCA 2H62C 2JQPA 2MJ4A 1JE9A 2N99A 2HLRA 5IMYC 4LFTA 1CRFA 1LX5B 2MJ0A 1F8UB 1H0JA 1MR6A 1KC4A 1BTEA 1IDLA 2LCRA 2VLWA 1COEA 2QC1A 2BHIA 2H7ZB 2CDXA 2LA1A 1IK8A 1ERGA 5DZ5A 4ZQYA 1IKCA 2HLQA 1RGJA 1I02A 1RL5A 2BTXA 1HC9B 3VTSA 1CCQA 1TXAA 2MFAA 2QJAC 1TFSA 1W6BA 4AEAA 2I9BE 2H8UA 2K3GA 1CDTA 4OM4A 2PJYB 1YWHA 1LXHA 3HH7A 1ERAA 4UY2C 1KXIA 4IYEA 1KL8A 1UG4A 1L4WA 2H64B 1FSSB 1CVOA 1KFHA 1DRSA 4BIKB 3U74U 2H64C 2H7ZA 1BXPA 1CDRA 1ABTA 1IDGA 1B41B 1ZADA 3ERAA 1FFJA 4P7UA 2J8BA 3KFDI 2CCXA 1HC9A 1CDSA 1CHVS 1REWC 1KBTA 1KBAA 1HAAA 2CRTA 3EBXA 1NEAA 4XJJA 2UWRA 3NEQA 4BDTB 5DO6A 1NYUA 1IJCA 3EVSC 3NDSA 1LJZA 1QM7A 2L03A 1QKDA 2QJBC 2UX2A 2CTXA 1IDHA 1NORA 4DO8A 1KU6B 1FRAA 3BT1U 1FF4A 2PJYC 2X8BB 2FD6U 5DU1A 1LSIA 3QB4B 1CREA 1IDIA 1NTNA 1F94A 2MHYA 2ERAA 1V6PA 1M9ZA 4EY8B 2GOOB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5EBX A;  3PLC A;  1JBD A;  2GOO C;  4FAO C;  1XT3 A;  2L5S A;  1IQ9 A;  3U73 U;  2NBT A;  1FAS A;  1NYS A;  4FAO E;  3KFD E;  1PLO A;  2ABX A;  1ONJ A;  1KTZ B;  1TGX A;  6EBX A;  4QTI U;  1TXB A;  2MUO A;  2H5F A;  2MUP A;  4HQP F;  3FEV A;  1KS6 A;  1ES7 B;  5IMT D;  1MAH F;  1LXG A;  1NTX A;  1VB0 A;  1S4Y A;  1HAJ A;  1G6M A;  1CXN A;  4OM5 A;  1NXB A;  1KBS A;  1CXO A;  2MJY A;  2OFS A;  2QJ9 C;  1CTX A;  3NH7 A;  3BT2 U;  2CRS A;  1QKE A;  1CDQ A;  2H62 D;  3LAQ U;  4RUD A;  1JGK A;  1HOY A;  2JVE A;  1CB9 A;  1COD A;  1FSC A;  2H62 C;  2JQP A;  2MJ4 A;  1JE9 A;  2N99 A;  2HLR A;  5IMY C;  4LFT A;  1CRF A;  1LX5 B;  2MJ0 A;  1F8U B;  1H0J A;  1MR6 A;  1KC4 A;  1BTE A;  1IDL A;  2LCR A;  2VLW A;  1COE A;  2QC1 A;  2BHI A;  2H7Z B;  2CDX A;  2LA1 A;  1IK8 A;  1ERG A;  5DZ5 A;  4ZQY A;  1IKC A;  2HLQ A;  1RGJ A;  1I02 A;  1RL5 A;  2BTX A;  1HC9 B;  3VTS A;  1CCQ A;  1TXA A;  2MFA A;  2QJA C;  1TFS A;  1W6B A;  4AEA A;  2I9B E;  2H8U A;  2K3G A;  1CDT A;  4OM4 A;  2PJY B;  1YWH A;  1LXH A;  3HH7 A;  1ERA A;  4UY2 C;  1KXI A;  4IYE A;  1KL8 A;  1UG4 A;  1L4W A;  2H64 B;  1FSS B;  1CVO A;  1KFH A;  1DRS A;  4BIK B;  3U74 U;  2H64 C;  2H7Z A;  1BXP A;  1CDR A;  1ABT A;  1IDG A;  1B41 B;  1ZAD A;  3ERA A;  1FFJ A;  4P7U A;  2J8B A;  3KFD I;  2CCX A;  1HC9 A;  1CDS A;  1CHV S;  1REW C;  1KBT A;  1KBA A;  1HAA A;  2CRT A;  3EBX A;  1NEA A;  4XJJ A;  2UWR A;  3NEQ A;  4BDT B;  5DO6 A;  1NYU A;  1IJC A;  3EVS C;  3NDS A;  1LJZ A;  1QM7 A;  2L03 A;  1QKD A;  2QJB C;  2UX2 A;  2CTX A;  1IDH A;  1NOR A;  4DO8 A;  1KU6 B;  1FRA A;  3BT1 U;  1FF4 A;  2PJY C;  2X8B B;  2FD6 U;  5DU1 A;  1LSI A;  3QB4 B;  1CRE A;  1IDI A;  1NTN A;  1F94 A;  2MHY A;  2ERA A;  1V6P A;  1M9Z A;  4EY8 B;  2GOO B; 
#chains in the Genus database with same CATH topology
 5EBX A;  3PLC A;  1JBD A;  2GOO C;  4FAO C;  1XT3 A;  2L5S A;  1IQ9 A;  3U73 U;  2NBT A;  1FAS A;  1NYS A;  4FAO E;  3KFD E;  1PLO A;  2ABX A;  1ONJ A;  1KTZ B;  1TGX A;  6EBX A;  4QTI U;  1TXB A;  2MUO A;  2H5F A;  4KSN A;  2MUP A;  4HQP F;  3FEV A;  1KS6 A;  1ES7 B;  5IMT D;  1MAH F;  1LXG A;  1NTX A;  1VB0 A;  1S4Y A;  1HAJ A;  1G6M A;  1CXN A;  4OM5 A;  1NXB A;  1KBS A;  1CXO A;  2MJY A;  2OFS A;  2QJ9 C;  1CTX A;  3NH7 A;  3BT2 U;  2CRS A;  1QKE A;  1CDQ A;  2H62 D;  3LAQ U;  4RUD A;  1JGK A;  1HOY A;  2JVE A;  1CB9 A;  1COD A;  1FSC A;  2H62 C;  2JQP A;  2MJ4 A;  1JE9 A;  2N99 A;  2HLR A;  5IMY C;  4LFT A;  1CRF A;  1LX5 B;  2MJ0 A;  1F8U B;  1H0J A;  1MR6 A;  1KC4 A;  1BTE A;  1IDL A;  2LCR A;  2VLW A;  1COE A;  2QC1 A;  2BHI A;  2H7Z B;  2CDX A;  2LA1 A;  1IK8 A;  1ERG A;  5DZ5 A;  4ZQY A;  1IKC A;  2HLQ A;  1RGJ A;  1I02 A;  1RL5 A;  2BTX A;  1HC9 B;  3VTS A;  1CCQ A;  1TXA A;  2MFA A;  2QJA C;  1TFS A;  1W6B A;  4AEA A;  2I9B E;  2H8U A;  2K3G A;  1CDT A;  4OM4 A;  2PJY B;  1YWH A;  1LXH A;  3HH7 A;  1ERA A;  4UY2 C;  1KXI A;  4IYE A;  1KL8 A;  1UG4 A;  1L4W A;  2H64 B;  1FSS B;  1CVO A;  1KFH A;  1DRS A;  4BIK B;  3U74 U;  2H64 C;  2H7Z A;  1BXP A;  1CDR A;  1ABT A;  1IDG A;  1B41 B;  1ZAD A;  3ERA A;  1FFJ A;  4P7U A;  2J8B A;  3KFD I;  2CCX A;  1HC9 A;  1CDS A;  1CHV S;  1REW C;  1KBT A;  1KBA A;  1HAA A;  2CRT A;  3EBX A;  1NEA A;  4XJJ A;  2UWR A;  3NEQ A;  4BDT B;  5DO6 A;  1NYU A;  1IJC A;  3EVS C;  3NDS A;  1LJZ A;  1QM7 A;  2L03 A;  1QKD A;  2QJB C;  2UX2 A;  2CTX A;  1IDH A;  1NOR A;  4DO8 A;  1KU6 B;  1FRA A;  3BT1 U;  1FF4 A;  2PJY C;  2X8B B;  2FD6 U;  5DU1 A;  1LSI A;  3QB4 B;  1CRE A;  1IDI A;  1NTN A;  1F94 A;  2MHY A;  2ERA A;  1V6P A;  1M9Z A;  4EY8 B;  2GOO B; 
#chains in the Genus database with same CATH homology
 5EBX A;  3PLC A;  1JBD A;  2GOO C;  4FAO C;  1XT3 A;  2L5S A;  1IQ9 A;  3U73 U;  2NBT A;  1FAS A;  1NYS A;  4FAO E;  3KFD E;  1PLO A;  2ABX A;  1ONJ A;  1KTZ B;  1TGX A;  6EBX A;  4QTI U;  1TXB A;  2MUO A;  2H5F A;  4KSN A;  2MUP A;  4HQP F;  3FEV A;  1KS6 A;  1ES7 B;  5IMT D;  1MAH F;  1LXG A;  1NTX A;  1VB0 A;  1S4Y A;  1HAJ A;  1G6M A;  1CXN A;  4OM5 A;  1NXB A;  1KBS A;  1CXO A;  2MJY A;  2OFS A;  2QJ9 C;  1CTX A;  3NH7 A;  3BT2 U;  2CRS A;  1QKE A;  1CDQ A;  2H62 D;  3LAQ U;  4RUD A;  1JGK A;  1HOY A;  2JVE A;  1CB9 A;  1COD A;  1FSC A;  2H62 C;  2JQP A;  2MJ4 A;  1JE9 A;  2N99 A;  2HLR A;  5IMY C;  4LFT A;  1CRF A;  1LX5 B;  2MJ0 A;  1F8U B;  1H0J A;  1MR6 A;  1KC4 A;  1BTE A;  1IDL A;  2LCR A;  2VLW A;  1COE A;  2QC1 A;  2BHI A;  2H7Z B;  2CDX A;  2LA1 A;  1IK8 A;  1ERG A;  5DZ5 A;  4ZQY A;  1IKC A;  2HLQ A;  1RGJ A;  1I02 A;  1RL5 A;  2BTX A;  1HC9 B;  3VTS A;  1CCQ A;  1TXA A;  2MFA A;  2QJA C;  1TFS A;  1W6B A;  4AEA A;  2I9B E;  2H8U A;  2K3G A;  1CDT A;  4OM4 A;  2PJY B;  1YWH A;  1LXH A;  3HH7 A;  1ERA A;  4UY2 C;  1KXI A;  4IYE A;  1KL8 A;  1UG4 A;  1L4W A;  2H64 B;  1FSS B;  1CVO A;  1KFH A;  1DRS A;  4BIK B;  3U74 U;  2H64 C;  2H7Z A;  1BXP A;  1CDR A;  1ABT A;  1IDG A;  1B41 B;  1ZAD A;  3ERA A;  1FFJ A;  4P7U A;  2J8B A;  3KFD I;  2CCX A;  1HC9 A;  1CDS A;  1CHV S;  1REW C;  1KBT A;  1KBA A;  1HAA A;  2CRT A;  3EBX A;  1NEA A;  4XJJ A;  2UWR A;  3NEQ A;  4BDT B;  5DO6 A;  1NYU A;  1IJC A;  3EVS C;  3NDS A;  1LJZ A;  1QM7 A;  2L03 A;  1QKD A;  2QJB C;  2UX2 A;  2CTX A;  1IDH A;  1NOR A;  4DO8 A;  1KU6 B;  1FRA A;  3BT1 U;  1FF4 A;  2PJY C;  2X8B B;  2FD6 U;  5DU1 A;  1LSI A;  3QB4 B;  1CRE A;  1IDI A;  1NTN A;  1F94 A;  2MHY A;  2ERA A;  1V6P A;  1M9Z A;  4EY8 B;  2GOO B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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