2QJBC

Crystal structure analysis of bmp-2 in complex with bmpr-ia variant ia/ib
Total Genus 15
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
85
structure length
85
Chain Sequence
TLPFLKCYCSHHCPEDAINNTCITNGHCFTMIEEDDQGETTLTSGCLGLEGSDFQCRDTPIPHQRRSIECCRTNLCNQYLQPTLP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Cytokine/receptor
source organism Homo sapiens
publication title Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome.
pubmed doi rcsb
molecule keywords Bone morphogenetic protein 2
total genus 15
structure length 85
sequence length 85
chains with identical sequence D
ec nomenclature ec 2.7.11.30: Receptor protein serine/threonine kinase.
pdb deposition date 2007-07-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01064 Activin_recp Activin types I and II receptor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 2qjbC00
1JBDA 1HC9A 1KXIA 1ZADA 2H62C 2QJBC 1KTZB 2JVEA 1FSSB 1KBSA 1F94A 2CTXA 1KBTA 1JE9A 1F8UB 1NEAA 2H7ZA 2L03A 2MJYA 3U74U 1KFHA 3BT1U 4IYEA 2QJ9C 2QC1A 1IJCA 2VLWA 1HOYA 2MJ4A 2BHIA 4OM5A 2FD6U 2ABXA 1NYUA 1TGXA 1FRAA 1NTNA 3EVSC 1KL8A 3QB4B 1W6BA 1KU6B 1CREA 2LA1A 1CRFA 2MUPA 2QJAC 2ERAA 2H64B 1CTXA 1CXOA 1CDRA 1COEA 1CDQA 3NDSA 2N99A 2H8UA 2I9BE 1V6PA 2J8BA 2CRTA 2CRSA 5DU1A 5IMYC 1CCQA 2GOOC 3FEVA 6EBXA 1ABTA 1VB0A 4UY2C 1FF4A 1TXAA 1BTEA 5EBXA 1QKEA 4QTIU 1KC4A 1ONJA 1HAJA 1IKCA 3EBXA 2UWRA 2H62D 1LSIA 4FAOE 1IK8A 2MUOA 3NEQA 1ERGA 1M9ZA 2CCXA 1MR6A 1CODA 1BXPA 2X8BB 1FSCA 1ERAA 2MFAA 4XJJA 3NH7A 3VTSA 4RUDA 1NTXA 1KBAA 1QKDA 4DO8A 2UX2A 1CHVS 2H64C 3U73U 5IMTD 1IDLA 2PJYB 2JQPA 4BDTB 1B41B 2L5SA 3BT2U 1I02A 1G6MA 1IQ9A 1S4YA 2H5FA 1IDGA 1TXBA 1NYSA 2HLRA 1FFJA 1LX5B 4HQPF 1DRSA 2K3GA 4OM4A 1H0JA 4ZQYA 1CVOA 2MHYA 3KFDI 1TFSA 1PLOA 1RGJA 4P7UA 1IDIA 1LXHA 1REWC 2NBTA 1UG4A 1HC9B 1LJZA 1NXBA 1FASA 1LXGA 1QM7A 4EY8B 1CDSA 3HH7A 1JGKA 1ES7B 1RL5A 2MJ0A 5DZ5A 2HLQA 4FAOC 1XT3A 2H7ZB 4LFTA 2BTXA 1YWHA 2PJYC 1KS6A 4AEAA 1L4WA 1CDTA 1CXNA 5DO6A 3KFDE 2GOOB 2LCRA 4BIKB 1NORA 3LAQU 1HAAA 3ERAA 1CB9A 1MAHF 1IDHA 3PLCA 2OFSA 2CDXA
chains in the Genus database with same CATH superfamily
1JBDA 1HC9A 1KXIA 1ZADA 2H62C 2QJBC 1KTZB 2JVEA 1FSSB 1KBSA 1F94A 2CTXA 1KBTA 1JE9A 1F8UB 1NEAA 2H7ZA 2L03A 2MJYA 3U74U 1KFHA 3BT1U 4IYEA 2QJ9C 2QC1A 1IJCA 2VLWA 1HOYA 2MJ4A 2BHIA 4KSNA 4OM5A 2FD6U 2ABXA 1NYUA 1TGXA 1FRAA 1NTNA 3EVSC 1KL8A 3QB4B 1W6BA 1KU6B 1CREA 2LA1A 1CRFA 2MUPA 2QJAC 2ERAA 2H64B 1CTXA 1CXOA 1CDRA 1COEA 1CDQA 3NDSA 2N99A 2H8UA 2I9BE 1V6PA 2J8BA 2CRTA 2CRSA 5DU1A 5IMYC 1CCQA 2GOOC 3FEVA 6EBXA 1ABTA 1VB0A 4UY2C 1FF4A 1TXAA 1BTEA 5EBXA 1QKEA 4QTIU 1KC4A 1ONJA 1HAJA 1IKCA 3EBXA 2UWRA 2H62D 1LSIA 4FAOE 1IK8A 2MUOA 3NEQA 1ERGA 1M9ZA 2CCXA 1MR6A 1CODA 1BXPA 2X8BB 1FSCA 1ERAA 2MFAA 4XJJA 3NH7A 3VTSA 4RUDA 1NTXA 1KBAA 1QKDA 4DO8A 2UX2A 1CHVS 2H64C 3U73U 5IMTD 1IDLA 2PJYB 2JQPA 4BDTB 1B41B 2L5SA 3BT2U 1I02A 1G6MA 1IQ9A 1S4YA 2H5FA 1IDGA 1TXBA 1NYSA 2HLRA 1FFJA 1LX5B 4HQPF 1DRSA 2K3GA 4OM4A 1H0JA 4ZQYA 1CVOA 2MHYA 3KFDI 1TFSA 1PLOA 1RGJA 4P7UA 1IDIA 1LXHA 1REWC 2NBTA 1UG4A 1HC9B 1LJZA 1NXBA 1FASA 1LXGA 1QM7A 4EY8B 1CDSA 3HH7A 1JGKA 1ES7B 1RL5A 2MJ0A 5DZ5A 2HLQA 4FAOC 1XT3A 2H7ZB 4LFTA 2BTXA 1YWHA 2PJYC 1KS6A 4AEAA 1L4WA 1CDTA 1CXNA 5DO6A 3KFDE 2GOOB 2LCRA 4BIKB 1NORA 3LAQU 1HAAA 3ERAA 1CB9A 1MAHF 1IDHA 3PLCA 2OFSA 2CDXA
chains in the Genus database with same CATH topology
1JBDA 1HC9A 1KXIA 1ZADA 2H62C 2QJBC 1KTZB 2JVEA 1FSSB 1KBSA 1F94A 2CTXA 1KBTA 1JE9A 1F8UB 1NEAA 2H7ZA 2L03A 2MJYA 3U74U 1KFHA 3BT1U 4IYEA 2QJ9C 2QC1A 1IJCA 2VLWA 1HOYA 2MJ4A 2BHIA 4KSNA 4OM5A 2FD6U 2ABXA 1NYUA 1TGXA 1FRAA 1NTNA 3EVSC 1KL8A 3QB4B 1W6BA 1KU6B 1CREA 2LA1A 1CRFA 2MUPA 2QJAC 2ERAA 2H64B 1CTXA 1CXOA 1CDRA 1COEA 1CDQA 3NDSA 2N99A 2H8UA 2I9BE 1V6PA 2J8BA 2CRTA 2CRSA 5DU1A 5IMYC 1CCQA 2GOOC 3FEVA 6EBXA 1ABTA 1VB0A 4UY2C 1FF4A 1TXAA 1BTEA 5EBXA 1QKEA 4QTIU 1KC4A 1ONJA 1HAJA 1IKCA 3EBXA 2UWRA 2H62D 1LSIA 4FAOE 1IK8A 2MUOA 3NEQA 1ERGA 1M9ZA 2CCXA 1MR6A 1CODA 1BXPA 2X8BB 1FSCA 1ERAA 2MFAA 4XJJA 3NH7A 3VTSA 4RUDA 1NTXA 1KBAA 1QKDA 4DO8A 2UX2A 1CHVS 2H64C 3U73U 5IMTD 1IDLA 2PJYB 2JQPA 4BDTB 1B41B 2L5SA 3BT2U 1I02A 1G6MA 1IQ9A 1S4YA 2H5FA 1IDGA 1TXBA 1NYSA 2HLRA 1FFJA 1LX5B 4HQPF 1DRSA 2K3GA 4OM4A 1H0JA 4ZQYA 1CVOA 2MHYA 3KFDI 1TFSA 1PLOA 1RGJA 4P7UA 1IDIA 1LXHA 1REWC 2NBTA 1UG4A 1HC9B 1LJZA 1NXBA 1FASA 1LXGA 1QM7A 4EY8B 1CDSA 3HH7A 1JGKA 1ES7B 1RL5A 2MJ0A 5DZ5A 2HLQA 4FAOC 1XT3A 2H7ZB 4LFTA 2BTXA 1YWHA 2PJYC 1KS6A 4AEAA 1L4WA 1CDTA 1CXNA 5DO6A 3KFDE 2GOOB 2LCRA 4BIKB 1NORA 3LAQU 1HAAA 3ERAA 1CB9A 1MAHF 1IDHA 3PLCA 2OFSA 2CDXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JBD A;  1HC9 A;  1KXI A;  1ZAD A;  2H62 C;  2QJB C;  1KTZ B;  2JVE A;  1FSS B;  1KBS A;  1F94 A;  2CTX A;  1KBT A;  1JE9 A;  1F8U B;  1NEA A;  2H7Z A;  2L03 A;  2MJY A;  3U74 U;  1KFH A;  3BT1 U;  4IYE A;  2QJ9 C;  2QC1 A;  1IJC A;  2VLW A;  1HOY A;  2MJ4 A;  2BHI A;  4OM5 A;  2FD6 U;  2ABX A;  1NYU A;  1TGX A;  1FRA A;  1NTN A;  3EVS C;  1KL8 A;  3QB4 B;  1W6B A;  1KU6 B;  1CRE A;  2LA1 A;  1CRF A;  2MUP A;  2QJA C;  2ERA A;  2H64 B;  1CTX A;  1CXO A;  1CDR A;  1COE A;  1CDQ A;  3NDS A;  2N99 A;  2H8U A;  2I9B E;  1V6P A;  2J8B A;  2CRT A;  2CRS A;  5DU1 A;  5IMY C;  1CCQ A;  2GOO C;  3FEV A;  6EBX A;  1ABT A;  1VB0 A;  4UY2 C;  1FF4 A;  1TXA A;  1BTE A;  5EBX A;  1QKE A;  4QTI U;  1KC4 A;  1ONJ A;  1HAJ A;  1IKC A;  3EBX A;  2UWR A;  2H62 D;  1LSI A;  4FAO E;  1IK8 A;  2MUO A;  3NEQ A;  1ERG A;  1M9Z A;  2CCX A;  1MR6 A;  1COD A;  1BXP A;  2X8B B;  1FSC A;  1ERA A;  2MFA A;  4XJJ A;  3NH7 A;  3VTS A;  4RUD A;  1NTX A;  1KBA A;  1QKD A;  4DO8 A;  2UX2 A;  1CHV S;  2H64 C;  3U73 U;  5IMT D;  1IDL A;  2PJY B;  2JQP A;  4BDT B;  1B41 B;  2L5S A;  3BT2 U;  1I02 A;  1G6M A;  1IQ9 A;  1S4Y A;  2H5F A;  1IDG A;  1TXB A;  1NYS A;  2HLR A;  1FFJ A;  1LX5 B;  4HQP F;  1DRS A;  2K3G A;  4OM4 A;  1H0J A;  4ZQY A;  1CVO A;  2MHY A;  3KFD I;  1TFS A;  1PLO A;  1RGJ A;  4P7U A;  1IDI A;  1LXH A;  1REW C;  2NBT A;  1UG4 A;  1HC9 B;  1LJZ A;  1NXB A;  1FAS A;  1LXG A;  1QM7 A;  4EY8 B;  1CDS A;  3HH7 A;  1JGK A;  1ES7 B;  1RL5 A;  2MJ0 A;  5DZ5 A;  2HLQ A;  4FAO C;  1XT3 A;  2H7Z B;  4LFT A;  2BTX A;  1YWH A;  2PJY C;  1KS6 A;  4AEA A;  1L4W A;  1CDT A;  1CXN A;  5DO6 A;  3KFD E;  2GOO B;  2LCR A;  4BIK B;  1NOR A;  3LAQ U;  1HAA A;  3ERA A;  1CB9 A;  1MAH F;  1IDH A;  3PLC A;  2OFS A;  2CDX A; 
#chains in the Genus database with same CATH topology
 1JBD A;  1HC9 A;  1KXI A;  1ZAD A;  2H62 C;  2QJB C;  1KTZ B;  2JVE A;  1FSS B;  1KBS A;  1F94 A;  2CTX A;  1KBT A;  1JE9 A;  1F8U B;  1NEA A;  2H7Z A;  2L03 A;  2MJY A;  3U74 U;  1KFH A;  3BT1 U;  4IYE A;  2QJ9 C;  2QC1 A;  1IJC A;  2VLW A;  1HOY A;  2MJ4 A;  2BHI A;  4KSN A;  4OM5 A;  2FD6 U;  2ABX A;  1NYU A;  1TGX A;  1FRA A;  1NTN A;  3EVS C;  1KL8 A;  3QB4 B;  1W6B A;  1KU6 B;  1CRE A;  2LA1 A;  1CRF A;  2MUP A;  2QJA C;  2ERA A;  2H64 B;  1CTX A;  1CXO A;  1CDR A;  1COE A;  1CDQ A;  3NDS A;  2N99 A;  2H8U A;  2I9B E;  1V6P A;  2J8B A;  2CRT A;  2CRS A;  5DU1 A;  5IMY C;  1CCQ A;  2GOO C;  3FEV A;  6EBX A;  1ABT A;  1VB0 A;  4UY2 C;  1FF4 A;  1TXA A;  1BTE A;  5EBX A;  1QKE A;  4QTI U;  1KC4 A;  1ONJ A;  1HAJ A;  1IKC A;  3EBX A;  2UWR A;  2H62 D;  1LSI A;  4FAO E;  1IK8 A;  2MUO A;  3NEQ A;  1ERG A;  1M9Z A;  2CCX A;  1MR6 A;  1COD A;  1BXP A;  2X8B B;  1FSC A;  1ERA A;  2MFA A;  4XJJ A;  3NH7 A;  3VTS A;  4RUD A;  1NTX A;  1KBA A;  1QKD A;  4DO8 A;  2UX2 A;  1CHV S;  2H64 C;  3U73 U;  5IMT D;  1IDL A;  2PJY B;  2JQP A;  4BDT B;  1B41 B;  2L5S A;  3BT2 U;  1I02 A;  1G6M A;  1IQ9 A;  1S4Y A;  2H5F A;  1IDG A;  1TXB A;  1NYS A;  2HLR A;  1FFJ A;  1LX5 B;  4HQP F;  1DRS A;  2K3G A;  4OM4 A;  1H0J A;  4ZQY A;  1CVO A;  2MHY A;  3KFD I;  1TFS A;  1PLO A;  1RGJ A;  4P7U A;  1IDI A;  1LXH A;  1REW C;  2NBT A;  1UG4 A;  1HC9 B;  1LJZ A;  1NXB A;  1FAS A;  1LXG A;  1QM7 A;  4EY8 B;  1CDS A;  3HH7 A;  1JGK A;  1ES7 B;  1RL5 A;  2MJ0 A;  5DZ5 A;  2HLQ A;  4FAO C;  1XT3 A;  2H7Z B;  4LFT A;  2BTX A;  1YWH A;  2PJY C;  1KS6 A;  4AEA A;  1L4W A;  1CDT A;  1CXN A;  5DO6 A;  3KFD E;  2GOO B;  2LCR A;  4BIK B;  1NOR A;  3LAQ U;  1HAA A;  3ERA A;  1CB9 A;  1MAH F;  1IDH A;  3PLC A;  2OFS A;  2CDX A; 
#chains in the Genus database with same CATH homology
 1JBD A;  1HC9 A;  1KXI A;  1ZAD A;  2H62 C;  2QJB C;  1KTZ B;  2JVE A;  1FSS B;  1KBS A;  1F94 A;  2CTX A;  1KBT A;  1JE9 A;  1F8U B;  1NEA A;  2H7Z A;  2L03 A;  2MJY A;  3U74 U;  1KFH A;  3BT1 U;  4IYE A;  2QJ9 C;  2QC1 A;  1IJC A;  2VLW A;  1HOY A;  2MJ4 A;  2BHI A;  4KSN A;  4OM5 A;  2FD6 U;  2ABX A;  1NYU A;  1TGX A;  1FRA A;  1NTN A;  3EVS C;  1KL8 A;  3QB4 B;  1W6B A;  1KU6 B;  1CRE A;  2LA1 A;  1CRF A;  2MUP A;  2QJA C;  2ERA A;  2H64 B;  1CTX A;  1CXO A;  1CDR A;  1COE A;  1CDQ A;  3NDS A;  2N99 A;  2H8U A;  2I9B E;  1V6P A;  2J8B A;  2CRT A;  2CRS A;  5DU1 A;  5IMY C;  1CCQ A;  2GOO C;  3FEV A;  6EBX A;  1ABT A;  1VB0 A;  4UY2 C;  1FF4 A;  1TXA A;  1BTE A;  5EBX A;  1QKE A;  4QTI U;  1KC4 A;  1ONJ A;  1HAJ A;  1IKC A;  3EBX A;  2UWR A;  2H62 D;  1LSI A;  4FAO E;  1IK8 A;  2MUO A;  3NEQ A;  1ERG A;  1M9Z A;  2CCX A;  1MR6 A;  1COD A;  1BXP A;  2X8B B;  1FSC A;  1ERA A;  2MFA A;  4XJJ A;  3NH7 A;  3VTS A;  4RUD A;  1NTX A;  1KBA A;  1QKD A;  4DO8 A;  2UX2 A;  1CHV S;  2H64 C;  3U73 U;  5IMT D;  1IDL A;  2PJY B;  2JQP A;  4BDT B;  1B41 B;  2L5S A;  3BT2 U;  1I02 A;  1G6M A;  1IQ9 A;  1S4Y A;  2H5F A;  1IDG A;  1TXB A;  1NYS A;  2HLR A;  1FFJ A;  1LX5 B;  4HQP F;  1DRS A;  2K3G A;  4OM4 A;  1H0J A;  4ZQY A;  1CVO A;  2MHY A;  3KFD I;  1TFS A;  1PLO A;  1RGJ A;  4P7U A;  1IDI A;  1LXH A;  1REW C;  2NBT A;  1UG4 A;  1HC9 B;  1LJZ A;  1NXB A;  1FAS A;  1LXG A;  1QM7 A;  4EY8 B;  1CDS A;  3HH7 A;  1JGK A;  1ES7 B;  1RL5 A;  2MJ0 A;  5DZ5 A;  2HLQ A;  4FAO C;  1XT3 A;  2H7Z B;  4LFT A;  2BTX A;  1YWH A;  2PJY C;  1KS6 A;  4AEA A;  1L4W A;  1CDT A;  1CXN A;  5DO6 A;  3KFD E;  2GOO B;  2LCR A;  4BIK B;  1NOR A;  3LAQ U;  1HAA A;  3ERA A;  1CB9 A;  1MAH F;  1IDH A;  3PLC A;  2OFS A;  2CDX A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...