3EVSC

Crystal structure of the gdf-5:bmp receptor ib complex.
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
85
structure length
85
Chain Sequence
ILRCKCHHHCPEDSVNNICSTDGYCFTMIEEDDSGMPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure analysis reveals a spring-loaded latch as molecular mechanism for GDF-5-type I receptor specificity.
pubmed doi rcsb
molecule tags Cytokine/transferase receptor
source organism Homo sapiens
molecule keywords Growth/differentiation factor 5
total genus 16
structure length 85
sequence length 85
ec nomenclature ec 2.7.11.30: Receptor protein serine/threonine kinase.
pdb deposition date 2008-10-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01064 Activin_recp Activin types I and II receptor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 3evsC00
4UY2C 2I9BE 1LX5B 1JBDA 1NYUA 3NH7A 4QTIU 1IDLA 2H7ZB 3VTSA 3LAQU 1IK8A 1KBTA 4P7UA 2PJYB 5IMYC 1NTNA 2MUPA 2UWRA 2MJYA 6EBXA 2H5FA 1H0JA 1MAHF 1FFJA 1QM7A 1V6PA 2ERAA 4LFTA 2BTXA 1BTEA 1I02A 3KFDE 1JGKA 1ONJA 1KFHA 1DRSA 1HC9B 4EY8B 1FRAA 1FSCA 2H62D 3QB4B 1IDHA 2HLQA 2H8UA 1CXOA 1KBAA 2FD6U 2QJAC 2H64C 2MJ4A 1ZADA 1F8UB 2QJBC 1LJZA 1M9ZA 1ABTA 1RGJA 1TGXA 1RL5A 2QC1A 2CRSA 4FAOE 5EBXA 1NXBA 1CVOA 3NDSA 1REWC 1LSIA 1JE9A 3EBXA 1IQ9A 2OFSA 1CODA 2BHIA 1XT3A 2X8BB 1HAAA 3BT1U 1KTZB 2LA1A 1F94A 1FF4A 1QKDA 1KBSA 2VLWA 3U74U 1IDGA 1CDQA 1LXGA 1B41B 1YWHA 1CCQA 2JVEA 2H7ZA 4RUDA 1FSSB 2MJ0A 1CDSA 2CCXA 2MFAA 1TFSA 2H64B 2MHYA 1KXIA 3PLCA 1KL8A 1KC4A 2H62C 2L5SA 1CHVS 2K3GA 3FEVA 1IKCA 3BT2U 4BIKB 4HQPF 2LCRA 1PLOA 1BXPA 2CDXA 1CB9A 4FAOC 1UG4A 3ERAA 1HC9A 1MR6A 1CREA 1CDTA 4OM4A 3NEQA 1CTXA 5DU1A 1IJCA 2GOOC 4IYEA 1COEA 2ABXA 2GOOB 2UX2A 2HLRA 2NBTA 2CRTA 1KS6A 4OM5A 1HAJA 1NEAA 1NYSA 3U73U 1VB0A 2PJYC 4DO8A 4AEAA 5DZ5A 1CXNA 1ERAA 1CRFA 1S4YA 2N99A 3KFDI 2L03A 1TXBA 1KU6B 3HH7A 1G6MA 2JQPA 2QJ9C 1HOYA 1TXAA 5DO6A 1ES7B 1FASA 2CTXA 1L4WA 1ERGA 4BDTB 1QKEA 2J8BA 1LXHA 1NORA 1W6BA 4XJJA 4ZQYA 1IDIA 1NTXA 5IMTD 1CDRA 3EVSC 2MUOA
chains in the Genus database with same CATH superfamily
4UY2C 2I9BE 1LX5B 1JBDA 1NYUA 3NH7A 4QTIU 1IDLA 2H7ZB 3VTSA 3LAQU 1IK8A 1KBTA 4P7UA 2PJYB 5IMYC 1NTNA 2MUPA 2UWRA 2MJYA 6EBXA 2H5FA 1H0JA 1MAHF 1FFJA 1QM7A 1V6PA 2ERAA 4LFTA 2BTXA 1BTEA 1I02A 3KFDE 1JGKA 1ONJA 1KFHA 1DRSA 1HC9B 4EY8B 1FRAA 1FSCA 2H62D 3QB4B 1IDHA 4KSNA 2HLQA 2H8UA 1CXOA 1KBAA 2FD6U 2QJAC 2H64C 2MJ4A 1ZADA 1F8UB 2QJBC 1LJZA 1M9ZA 1ABTA 1RGJA 1TGXA 1RL5A 2QC1A 2CRSA 4FAOE 5EBXA 1NXBA 1CVOA 3NDSA 1REWC 1LSIA 1JE9A 3EBXA 1IQ9A 2OFSA 1CODA 2BHIA 1XT3A 2X8BB 1HAAA 3BT1U 1KTZB 2LA1A 1F94A 1FF4A 1QKDA 1KBSA 2VLWA 3U74U 1IDGA 1CDQA 1LXGA 1B41B 1YWHA 1CCQA 2JVEA 2H7ZA 4RUDA 1FSSB 2MJ0A 1CDSA 2CCXA 2MFAA 1TFSA 2H64B 2MHYA 1KXIA 3PLCA 1KL8A 1KC4A 2H62C 2L5SA 1CHVS 2K3GA 3FEVA 1IKCA 3BT2U 4BIKB 4HQPF 2LCRA 1PLOA 1BXPA 2CDXA 1CB9A 4FAOC 1UG4A 3ERAA 1HC9A 1MR6A 1CREA 1CDTA 4OM4A 3NEQA 1CTXA 5DU1A 1IJCA 2GOOC 4IYEA 1COEA 2ABXA 2GOOB 2UX2A 2HLRA 2NBTA 2CRTA 1KS6A 4OM5A 1HAJA 1NEAA 1NYSA 3U73U 1VB0A 2PJYC 4DO8A 4AEAA 5DZ5A 1CXNA 1ERAA 1CRFA 1S4YA 2N99A 3KFDI 2L03A 1TXBA 1KU6B 3HH7A 1G6MA 2JQPA 2QJ9C 1HOYA 1TXAA 5DO6A 1ES7B 1FASA 2CTXA 1L4WA 1ERGA 4BDTB 1QKEA 2J8BA 1LXHA 1NORA 1W6BA 4XJJA 4ZQYA 1IDIA 1NTXA 5IMTD 1CDRA 3EVSC 2MUOA
chains in the Genus database with same CATH topology
4UY2C 2I9BE 1LX5B 1JBDA 1NYUA 3NH7A 4QTIU 1IDLA 2H7ZB 3VTSA 3LAQU 1IK8A 1KBTA 4P7UA 2PJYB 5IMYC 1NTNA 2MUPA 2UWRA 2MJYA 6EBXA 2H5FA 1H0JA 1MAHF 1FFJA 1QM7A 1V6PA 2ERAA 4LFTA 2BTXA 1BTEA 1I02A 3KFDE 1JGKA 1ONJA 1KFHA 1DRSA 1HC9B 4EY8B 1FRAA 1FSCA 2H62D 3QB4B 1IDHA 4KSNA 2HLQA 2H8UA 1CXOA 1KBAA 2FD6U 2QJAC 2H64C 2MJ4A 1ZADA 1F8UB 2QJBC 1LJZA 1M9ZA 1ABTA 1RGJA 1TGXA 1RL5A 2QC1A 2CRSA 4FAOE 5EBXA 1NXBA 1CVOA 3NDSA 1REWC 1LSIA 1JE9A 3EBXA 1IQ9A 2OFSA 1CODA 2BHIA 1XT3A 2X8BB 1HAAA 3BT1U 1KTZB 2LA1A 1F94A 1FF4A 1QKDA 1KBSA 2VLWA 3U74U 1IDGA 1CDQA 1LXGA 1B41B 1YWHA 1CCQA 2JVEA 2H7ZA 4RUDA 1FSSB 2MJ0A 1CDSA 2CCXA 2MFAA 1TFSA 2H64B 2MHYA 1KXIA 3PLCA 1KL8A 1KC4A 2H62C 2L5SA 1CHVS 2K3GA 3FEVA 1IKCA 3BT2U 4BIKB 4HQPF 2LCRA 1PLOA 1BXPA 2CDXA 1CB9A 4FAOC 1UG4A 3ERAA 1HC9A 1MR6A 1CREA 1CDTA 4OM4A 3NEQA 1CTXA 5DU1A 1IJCA 2GOOC 4IYEA 1COEA 2ABXA 2GOOB 2UX2A 2HLRA 2NBTA 2CRTA 1KS6A 4OM5A 1HAJA 1NEAA 1NYSA 3U73U 1VB0A 2PJYC 4DO8A 4AEAA 5DZ5A 1CXNA 1ERAA 1CRFA 1S4YA 2N99A 3KFDI 2L03A 1TXBA 1KU6B 3HH7A 1G6MA 2JQPA 2QJ9C 1HOYA 1TXAA 5DO6A 1ES7B 1FASA 2CTXA 1L4WA 1ERGA 4BDTB 1QKEA 2J8BA 1LXHA 1NORA 1W6BA 4XJJA 4ZQYA 1IDIA 1NTXA 5IMTD 1CDRA 3EVSC 2MUOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UY2 C;  2I9B E;  1LX5 B;  1JBD A;  1NYU A;  3NH7 A;  4QTI U;  1IDL A;  2H7Z B;  3VTS A;  3LAQ U;  1IK8 A;  1KBT A;  4P7U A;  2PJY B;  5IMY C;  1NTN A;  2MUP A;  2UWR A;  2MJY A;  6EBX A;  2H5F A;  1H0J A;  1MAH F;  1FFJ A;  1QM7 A;  1V6P A;  2ERA A;  4LFT A;  2BTX A;  1BTE A;  1I02 A;  3KFD E;  1JGK A;  1ONJ A;  1KFH A;  1DRS A;  1HC9 B;  4EY8 B;  1FRA A;  1FSC A;  2H62 D;  3QB4 B;  1IDH A;  2HLQ A;  2H8U A;  1CXO A;  1KBA A;  2FD6 U;  2QJA C;  2H64 C;  2MJ4 A;  1ZAD A;  1F8U B;  2QJB C;  1LJZ A;  1M9Z A;  1ABT A;  1RGJ A;  1TGX A;  1RL5 A;  2QC1 A;  2CRS A;  4FAO E;  5EBX A;  1NXB A;  1CVO A;  3NDS A;  1REW C;  1LSI A;  1JE9 A;  3EBX A;  1IQ9 A;  2OFS A;  1COD A;  2BHI A;  1XT3 A;  2X8B B;  1HAA A;  3BT1 U;  1KTZ B;  2LA1 A;  1F94 A;  1FF4 A;  1QKD A;  1KBS A;  2VLW A;  3U74 U;  1IDG A;  1CDQ A;  1LXG A;  1B41 B;  1YWH A;  1CCQ A;  2JVE A;  2H7Z A;  4RUD A;  1FSS B;  2MJ0 A;  1CDS A;  2CCX A;  2MFA A;  1TFS A;  2H64 B;  2MHY A;  1KXI A;  3PLC A;  1KL8 A;  1KC4 A;  2H62 C;  2L5S A;  1CHV S;  2K3G A;  3FEV A;  1IKC A;  3BT2 U;  4BIK B;  4HQP F;  2LCR A;  1PLO A;  1BXP A;  2CDX A;  1CB9 A;  4FAO C;  1UG4 A;  3ERA A;  1HC9 A;  1MR6 A;  1CRE A;  1CDT A;  4OM4 A;  3NEQ A;  1CTX A;  5DU1 A;  1IJC A;  2GOO C;  4IYE A;  1COE A;  2ABX A;  2GOO B;  2UX2 A;  2HLR A;  2NBT A;  2CRT A;  1KS6 A;  4OM5 A;  1HAJ A;  1NEA A;  1NYS A;  3U73 U;  1VB0 A;  2PJY C;  4DO8 A;  4AEA A;  5DZ5 A;  1CXN A;  1ERA A;  1CRF A;  1S4Y A;  2N99 A;  3KFD I;  2L03 A;  1TXB A;  1KU6 B;  3HH7 A;  1G6M A;  2JQP A;  2QJ9 C;  1HOY A;  1TXA A;  5DO6 A;  1ES7 B;  1FAS A;  2CTX A;  1L4W A;  1ERG A;  4BDT B;  1QKE A;  2J8B A;  1LXH A;  1NOR A;  1W6B A;  4XJJ A;  4ZQY A;  1IDI A;  1NTX A;  5IMT D;  1CDR A;  3EVS C;  2MUO A; 
#chains in the Genus database with same CATH topology
 4UY2 C;  2I9B E;  1LX5 B;  1JBD A;  1NYU A;  3NH7 A;  4QTI U;  1IDL A;  2H7Z B;  3VTS A;  3LAQ U;  1IK8 A;  1KBT A;  4P7U A;  2PJY B;  5IMY C;  1NTN A;  2MUP A;  2UWR A;  2MJY A;  6EBX A;  2H5F A;  1H0J A;  1MAH F;  1FFJ A;  1QM7 A;  1V6P A;  2ERA A;  4LFT A;  2BTX A;  1BTE A;  1I02 A;  3KFD E;  1JGK A;  1ONJ A;  1KFH A;  1DRS A;  1HC9 B;  4EY8 B;  1FRA A;  1FSC A;  2H62 D;  3QB4 B;  1IDH A;  4KSN A;  2HLQ A;  2H8U A;  1CXO A;  1KBA A;  2FD6 U;  2QJA C;  2H64 C;  2MJ4 A;  1ZAD A;  1F8U B;  2QJB C;  1LJZ A;  1M9Z A;  1ABT A;  1RGJ A;  1TGX A;  1RL5 A;  2QC1 A;  2CRS A;  4FAO E;  5EBX A;  1NXB A;  1CVO A;  3NDS A;  1REW C;  1LSI A;  1JE9 A;  3EBX A;  1IQ9 A;  2OFS A;  1COD A;  2BHI A;  1XT3 A;  2X8B B;  1HAA A;  3BT1 U;  1KTZ B;  2LA1 A;  1F94 A;  1FF4 A;  1QKD A;  1KBS A;  2VLW A;  3U74 U;  1IDG A;  1CDQ A;  1LXG A;  1B41 B;  1YWH A;  1CCQ A;  2JVE A;  2H7Z A;  4RUD A;  1FSS B;  2MJ0 A;  1CDS A;  2CCX A;  2MFA A;  1TFS A;  2H64 B;  2MHY A;  1KXI A;  3PLC A;  1KL8 A;  1KC4 A;  2H62 C;  2L5S A;  1CHV S;  2K3G A;  3FEV A;  1IKC A;  3BT2 U;  4BIK B;  4HQP F;  2LCR A;  1PLO A;  1BXP A;  2CDX A;  1CB9 A;  4FAO C;  1UG4 A;  3ERA A;  1HC9 A;  1MR6 A;  1CRE A;  1CDT A;  4OM4 A;  3NEQ A;  1CTX A;  5DU1 A;  1IJC A;  2GOO C;  4IYE A;  1COE A;  2ABX A;  2GOO B;  2UX2 A;  2HLR A;  2NBT A;  2CRT A;  1KS6 A;  4OM5 A;  1HAJ A;  1NEA A;  1NYS A;  3U73 U;  1VB0 A;  2PJY C;  4DO8 A;  4AEA A;  5DZ5 A;  1CXN A;  1ERA A;  1CRF A;  1S4Y A;  2N99 A;  3KFD I;  2L03 A;  1TXB A;  1KU6 B;  3HH7 A;  1G6M A;  2JQP A;  2QJ9 C;  1HOY A;  1TXA A;  5DO6 A;  1ES7 B;  1FAS A;  2CTX A;  1L4W A;  1ERG A;  4BDT B;  1QKE A;  2J8B A;  1LXH A;  1NOR A;  1W6B A;  4XJJ A;  4ZQY A;  1IDI A;  1NTX A;  5IMT D;  1CDR A;  3EVS C;  2MUO A; 
#chains in the Genus database with same CATH homology
 4UY2 C;  2I9B E;  1LX5 B;  1JBD A;  1NYU A;  3NH7 A;  4QTI U;  1IDL A;  2H7Z B;  3VTS A;  3LAQ U;  1IK8 A;  1KBT A;  4P7U A;  2PJY B;  5IMY C;  1NTN A;  2MUP A;  2UWR A;  2MJY A;  6EBX A;  2H5F A;  1H0J A;  1MAH F;  1FFJ A;  1QM7 A;  1V6P A;  2ERA A;  4LFT A;  2BTX A;  1BTE A;  1I02 A;  3KFD E;  1JGK A;  1ONJ A;  1KFH A;  1DRS A;  1HC9 B;  4EY8 B;  1FRA A;  1FSC A;  2H62 D;  3QB4 B;  1IDH A;  4KSN A;  2HLQ A;  2H8U A;  1CXO A;  1KBA A;  2FD6 U;  2QJA C;  2H64 C;  2MJ4 A;  1ZAD A;  1F8U B;  2QJB C;  1LJZ A;  1M9Z A;  1ABT A;  1RGJ A;  1TGX A;  1RL5 A;  2QC1 A;  2CRS A;  4FAO E;  5EBX A;  1NXB A;  1CVO A;  3NDS A;  1REW C;  1LSI A;  1JE9 A;  3EBX A;  1IQ9 A;  2OFS A;  1COD A;  2BHI A;  1XT3 A;  2X8B B;  1HAA A;  3BT1 U;  1KTZ B;  2LA1 A;  1F94 A;  1FF4 A;  1QKD A;  1KBS A;  2VLW A;  3U74 U;  1IDG A;  1CDQ A;  1LXG A;  1B41 B;  1YWH A;  1CCQ A;  2JVE A;  2H7Z A;  4RUD A;  1FSS B;  2MJ0 A;  1CDS A;  2CCX A;  2MFA A;  1TFS A;  2H64 B;  2MHY A;  1KXI A;  3PLC A;  1KL8 A;  1KC4 A;  2H62 C;  2L5S A;  1CHV S;  2K3G A;  3FEV A;  1IKC A;  3BT2 U;  4BIK B;  4HQP F;  2LCR A;  1PLO A;  1BXP A;  2CDX A;  1CB9 A;  4FAO C;  1UG4 A;  3ERA A;  1HC9 A;  1MR6 A;  1CRE A;  1CDT A;  4OM4 A;  3NEQ A;  1CTX A;  5DU1 A;  1IJC A;  2GOO C;  4IYE A;  1COE A;  2ABX A;  2GOO B;  2UX2 A;  2HLR A;  2NBT A;  2CRT A;  1KS6 A;  4OM5 A;  1HAJ A;  1NEA A;  1NYS A;  3U73 U;  1VB0 A;  2PJY C;  4DO8 A;  4AEA A;  5DZ5 A;  1CXN A;  1ERA A;  1CRF A;  1S4Y A;  2N99 A;  3KFD I;  2L03 A;  1TXB A;  1KU6 B;  3HH7 A;  1G6M A;  2JQP A;  2QJ9 C;  1HOY A;  1TXA A;  5DO6 A;  1ES7 B;  1FAS A;  2CTX A;  1L4W A;  1ERG A;  4BDT B;  1QKE A;  2J8B A;  1LXH A;  1NOR A;  1W6B A;  4XJJ A;  4ZQY A;  1IDI A;  1NTX A;  5IMT D;  1CDR A;  3EVS C;  2MUO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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