3EVSC

Crystal structure of the gdf-5:bmp receptor ib complex.
Total Genus 16
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
85
structure length
85
Chain Sequence
ILRCKCHHHCPEDSVNNICSTDGYCFTMIEEDDSGMPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Cytokine/transferase receptor
source organism Homo sapiens
publication title Crystal structure analysis reveals a spring-loaded latch as molecular mechanism for GDF-5-type I receptor specificity.
pubmed doi rcsb
molecule keywords Growth/differentiation factor 5
total genus 16
structure length 85
sequence length 85
ec nomenclature ec 2.7.11.30: Receptor protein serine/threonine kinase.
pdb deposition date 2008-10-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01064 Activin_recp Activin types I and II receptor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 3evsC00
2H7ZA 1F94A 1CHVS 3QB4B 4RUDA 2L5SA 3KFDI 1H0JA 1NXBA 3PLCA 1IKCA 1FSCA 1FRAA 2UWRA 1CDSA 1CREA 1I02A 1L4WA 6EBXA 3BT1U 5IMTD 2CCXA 4BIKB 1TGXA 3KFDE 2ABXA 4QTIU 1LJZA 1CDRA 1CTXA 1YWHA 4OM4A 1NTXA 3EBXA 1ES7B 2BTXA 1IQ9A 4ZQYA 1NTNA 1TXBA 3FEVA 4BDTB 1CCQA 1FSSB 4AEAA 4P7UA 1CRFA 1QKDA 3ERAA 2UX2A 1IDHA 1TXAA 2ERAA 2FD6U 1RL5A 1BTEA 4FAOC 4HQPF 1ABTA 3LAQU 2MJ4A 1XT3A 2X8BB 1FFJA 3U73U 1S4YA 4EY8B 1COEA 2VLWA 1KBAA 2OFSA 1RGJA 1KFHA 1CODA 1HC9B 1TFSA 1NEAA 3NH7A 1KU6B 4XJJA 2GOOB 1KTZB 1DRSA 2HLRA 4FAOE 4UY2C 2HLQA 5DZ5A 5DO6A 2QJBC 4IYEA 1HAJA 2K3GA 1BXPA 1NYSA 1HC9A 1MR6A 3U74U 1W6BA 1CVOA 1LX5B 5EBXA 1JBDA 1NYUA 1NORA 4DO8A 1V6PA 2PJYB 1HOYA 5DU1A 2JQPA 1KXIA 2H62D 2MJ0A 1IDLA 1JGKA 5IMYC 2QC1A 2BHIA 1ONJA 1QKEA 1IDGA 2L03A 4LFTA 1KS6A 1UG4A 1FF4A 3HH7A 2MHYA 3EVSC 1LXHA 1M9ZA 2H62C 1REWC 3BT2U 2CRSA 1ERAA 2H64B 2LA1A 2MUOA 2PJYC 2LCRA 4OM5A 1PLOA 1B41B 2I9BE 1KL8A 2QJAC 1CXNA 1KBSA 1IJCA 1KC4A 2MJYA 1LSIA 1QM7A 2CTXA 1FASA 2CRTA 1ZADA 1CDTA 1CDQA 2GOOC 2J8BA 2MFAA 2CDXA 2N99A 2NBTA 1LXGA 3NEQA 2H7ZB 1F8UB 2H64C 1IDIA 1KBTA 2H5FA 3VTSA 1CXOA 2H8UA 2MUPA 1HAAA 1VB0A 1CB9A 1G6MA 3NDSA 1IK8A 1ERGA 2JVEA 2QJ9C 1JE9A 1MAHF
chains in the Genus database with same CATH superfamily
2H7ZA 1F94A 1CHVS 3QB4B 4RUDA 2L5SA 3KFDI 1H0JA 1NXBA 3PLCA 1IKCA 1FSCA 1FRAA 2UWRA 1CDSA 1CREA 1I02A 1L4WA 6EBXA 3BT1U 5IMTD 2CCXA 4BIKB 4KSNA 1TGXA 3KFDE 2ABXA 4QTIU 1LJZA 1CDRA 1CTXA 1YWHA 4OM4A 1NTXA 3EBXA 1ES7B 2BTXA 1IQ9A 4ZQYA 1NTNA 1TXBA 3FEVA 4BDTB 1CCQA 1FSSB 4AEAA 4P7UA 1CRFA 1QKDA 3ERAA 2UX2A 1IDHA 1TXAA 2ERAA 2FD6U 1RL5A 1BTEA 4FAOC 4HQPF 1ABTA 3LAQU 2MJ4A 1XT3A 2X8BB 1FFJA 3U73U 1S4YA 4EY8B 1COEA 2VLWA 1KBAA 2OFSA 1RGJA 1KFHA 1CODA 1HC9B 1TFSA 1NEAA 3NH7A 1KU6B 4XJJA 2GOOB 1KTZB 1DRSA 2HLRA 4FAOE 4UY2C 2HLQA 5DZ5A 5DO6A 2QJBC 4IYEA 1HAJA 2K3GA 1BXPA 1NYSA 1HC9A 1MR6A 3U74U 1W6BA 1CVOA 1LX5B 5EBXA 1JBDA 1NYUA 1NORA 4DO8A 1V6PA 2PJYB 1HOYA 5DU1A 2JQPA 1KXIA 2H62D 2MJ0A 1IDLA 1JGKA 5IMYC 2QC1A 2BHIA 1ONJA 1QKEA 1IDGA 2L03A 4LFTA 1KS6A 1UG4A 1FF4A 3HH7A 2MHYA 3EVSC 1LXHA 1M9ZA 2H62C 1REWC 3BT2U 2CRSA 1ERAA 2H64B 2LA1A 2MUOA 2PJYC 2LCRA 4OM5A 1PLOA 1B41B 2I9BE 1KL8A 2QJAC 1CXNA 1KBSA 1IJCA 1KC4A 2MJYA 1LSIA 1QM7A 2CTXA 1FASA 2CRTA 1ZADA 1CDTA 1CDQA 2GOOC 2J8BA 2MFAA 2CDXA 2N99A 2NBTA 1LXGA 3NEQA 2H7ZB 1F8UB 2H64C 1IDIA 1KBTA 2H5FA 3VTSA 1CXOA 2H8UA 2MUPA 1HAAA 1VB0A 1CB9A 1G6MA 3NDSA 1IK8A 1ERGA 2JVEA 2QJ9C 1JE9A 1MAHF
chains in the Genus database with same CATH topology
2H7ZA 1F94A 1CHVS 3QB4B 4RUDA 2L5SA 3KFDI 1H0JA 1NXBA 3PLCA 1IKCA 1FSCA 1FRAA 2UWRA 1CDSA 1CREA 1I02A 1L4WA 6EBXA 3BT1U 5IMTD 2CCXA 4BIKB 4KSNA 1TGXA 3KFDE 2ABXA 4QTIU 1LJZA 1CDRA 1CTXA 1YWHA 4OM4A 1NTXA 3EBXA 1ES7B 2BTXA 1IQ9A 4ZQYA 1NTNA 1TXBA 3FEVA 4BDTB 1CCQA 1FSSB 4AEAA 4P7UA 1CRFA 1QKDA 3ERAA 2UX2A 1IDHA 1TXAA 2ERAA 2FD6U 1RL5A 1BTEA 4FAOC 4HQPF 1ABTA 3LAQU 2MJ4A 1XT3A 2X8BB 1FFJA 3U73U 1S4YA 4EY8B 1COEA 2VLWA 1KBAA 2OFSA 1RGJA 1KFHA 1CODA 1HC9B 1TFSA 1NEAA 3NH7A 1KU6B 4XJJA 2GOOB 1KTZB 1DRSA 2HLRA 4FAOE 4UY2C 2HLQA 5DZ5A 5DO6A 2QJBC 4IYEA 1HAJA 2K3GA 1BXPA 1NYSA 1HC9A 1MR6A 3U74U 1W6BA 1CVOA 1LX5B 5EBXA 1JBDA 1NYUA 1NORA 4DO8A 1V6PA 2PJYB 1HOYA 5DU1A 2JQPA 1KXIA 2H62D 2MJ0A 1IDLA 1JGKA 5IMYC 2QC1A 2BHIA 1ONJA 1QKEA 1IDGA 2L03A 4LFTA 1KS6A 1UG4A 1FF4A 3HH7A 2MHYA 3EVSC 1LXHA 1M9ZA 2H62C 1REWC 3BT2U 2CRSA 1ERAA 2H64B 2LA1A 2MUOA 2PJYC 2LCRA 4OM5A 1PLOA 1B41B 2I9BE 1KL8A 2QJAC 1CXNA 1KBSA 1IJCA 1KC4A 2MJYA 1LSIA 1QM7A 2CTXA 1FASA 2CRTA 1ZADA 1CDTA 1CDQA 2GOOC 2J8BA 2MFAA 2CDXA 2N99A 2NBTA 1LXGA 3NEQA 2H7ZB 1F8UB 2H64C 1IDIA 1KBTA 2H5FA 3VTSA 1CXOA 2H8UA 2MUPA 1HAAA 1VB0A 1CB9A 1G6MA 3NDSA 1IK8A 1ERGA 2JVEA 2QJ9C 1JE9A 1MAHF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2H7Z A;  1F94 A;  1CHV S;  3QB4 B;  4RUD A;  2L5S A;  3KFD I;  1H0J A;  1NXB A;  3PLC A;  1IKC A;  1FSC A;  1FRA A;  2UWR A;  1CDS A;  1CRE A;  1I02 A;  1L4W A;  6EBX A;  3BT1 U;  5IMT D;  2CCX A;  4BIK B;  1TGX A;  3KFD E;  2ABX A;  4QTI U;  1LJZ A;  1CDR A;  1CTX A;  1YWH A;  4OM4 A;  1NTX A;  3EBX A;  1ES7 B;  2BTX A;  1IQ9 A;  4ZQY A;  1NTN A;  1TXB A;  3FEV A;  4BDT B;  1CCQ A;  1FSS B;  4AEA A;  4P7U A;  1CRF A;  1QKD A;  3ERA A;  2UX2 A;  1IDH A;  1TXA A;  2ERA A;  2FD6 U;  1RL5 A;  1BTE A;  4FAO C;  4HQP F;  1ABT A;  3LAQ U;  2MJ4 A;  1XT3 A;  2X8B B;  1FFJ A;  3U73 U;  1S4Y A;  4EY8 B;  1COE A;  2VLW A;  1KBA A;  2OFS A;  1RGJ A;  1KFH A;  1COD A;  1HC9 B;  1TFS A;  1NEA A;  3NH7 A;  1KU6 B;  4XJJ A;  2GOO B;  1KTZ B;  1DRS A;  2HLR A;  4FAO E;  4UY2 C;  2HLQ A;  5DZ5 A;  5DO6 A;  2QJB C;  4IYE A;  1HAJ A;  2K3G A;  1BXP A;  1NYS A;  1HC9 A;  1MR6 A;  3U74 U;  1W6B A;  1CVO A;  1LX5 B;  5EBX A;  1JBD A;  1NYU A;  1NOR A;  4DO8 A;  1V6P A;  2PJY B;  1HOY A;  5DU1 A;  2JQP A;  1KXI A;  2H62 D;  2MJ0 A;  1IDL A;  1JGK A;  5IMY C;  2QC1 A;  2BHI A;  1ONJ A;  1QKE A;  1IDG A;  2L03 A;  4LFT A;  1KS6 A;  1UG4 A;  1FF4 A;  3HH7 A;  2MHY A;  3EVS C;  1LXH A;  1M9Z A;  2H62 C;  1REW C;  3BT2 U;  2CRS A;  1ERA A;  2H64 B;  2LA1 A;  2MUO A;  2PJY C;  2LCR A;  4OM5 A;  1PLO A;  1B41 B;  2I9B E;  1KL8 A;  2QJA C;  1CXN A;  1KBS A;  1IJC A;  1KC4 A;  2MJY A;  1LSI A;  1QM7 A;  2CTX A;  1FAS A;  2CRT A;  1ZAD A;  1CDT A;  1CDQ A;  2GOO C;  2J8B A;  2MFA A;  2CDX A;  2N99 A;  2NBT A;  1LXG A;  3NEQ A;  2H7Z B;  1F8U B;  2H64 C;  1IDI A;  1KBT A;  2H5F A;  3VTS A;  1CXO A;  2H8U A;  2MUP A;  1HAA A;  1VB0 A;  1CB9 A;  1G6M A;  3NDS A;  1IK8 A;  1ERG A;  2JVE A;  2QJ9 C;  1JE9 A;  1MAH F; 
#chains in the Genus database with same CATH topology
 2H7Z A;  1F94 A;  1CHV S;  3QB4 B;  4RUD A;  2L5S A;  3KFD I;  1H0J A;  1NXB A;  3PLC A;  1IKC A;  1FSC A;  1FRA A;  2UWR A;  1CDS A;  1CRE A;  1I02 A;  1L4W A;  6EBX A;  3BT1 U;  5IMT D;  2CCX A;  4BIK B;  4KSN A;  1TGX A;  3KFD E;  2ABX A;  4QTI U;  1LJZ A;  1CDR A;  1CTX A;  1YWH A;  4OM4 A;  1NTX A;  3EBX A;  1ES7 B;  2BTX A;  1IQ9 A;  4ZQY A;  1NTN A;  1TXB A;  3FEV A;  4BDT B;  1CCQ A;  1FSS B;  4AEA A;  4P7U A;  1CRF A;  1QKD A;  3ERA A;  2UX2 A;  1IDH A;  1TXA A;  2ERA A;  2FD6 U;  1RL5 A;  1BTE A;  4FAO C;  4HQP F;  1ABT A;  3LAQ U;  2MJ4 A;  1XT3 A;  2X8B B;  1FFJ A;  3U73 U;  1S4Y A;  4EY8 B;  1COE A;  2VLW A;  1KBA A;  2OFS A;  1RGJ A;  1KFH A;  1COD A;  1HC9 B;  1TFS A;  1NEA A;  3NH7 A;  1KU6 B;  4XJJ A;  2GOO B;  1KTZ B;  1DRS A;  2HLR A;  4FAO E;  4UY2 C;  2HLQ A;  5DZ5 A;  5DO6 A;  2QJB C;  4IYE A;  1HAJ A;  2K3G A;  1BXP A;  1NYS A;  1HC9 A;  1MR6 A;  3U74 U;  1W6B A;  1CVO A;  1LX5 B;  5EBX A;  1JBD A;  1NYU A;  1NOR A;  4DO8 A;  1V6P A;  2PJY B;  1HOY A;  5DU1 A;  2JQP A;  1KXI A;  2H62 D;  2MJ0 A;  1IDL A;  1JGK A;  5IMY C;  2QC1 A;  2BHI A;  1ONJ A;  1QKE A;  1IDG A;  2L03 A;  4LFT A;  1KS6 A;  1UG4 A;  1FF4 A;  3HH7 A;  2MHY A;  3EVS C;  1LXH A;  1M9Z A;  2H62 C;  1REW C;  3BT2 U;  2CRS A;  1ERA A;  2H64 B;  2LA1 A;  2MUO A;  2PJY C;  2LCR A;  4OM5 A;  1PLO A;  1B41 B;  2I9B E;  1KL8 A;  2QJA C;  1CXN A;  1KBS A;  1IJC A;  1KC4 A;  2MJY A;  1LSI A;  1QM7 A;  2CTX A;  1FAS A;  2CRT A;  1ZAD A;  1CDT A;  1CDQ A;  2GOO C;  2J8B A;  2MFA A;  2CDX A;  2N99 A;  2NBT A;  1LXG A;  3NEQ A;  2H7Z B;  1F8U B;  2H64 C;  1IDI A;  1KBT A;  2H5F A;  3VTS A;  1CXO A;  2H8U A;  2MUP A;  1HAA A;  1VB0 A;  1CB9 A;  1G6M A;  3NDS A;  1IK8 A;  1ERG A;  2JVE A;  2QJ9 C;  1JE9 A;  1MAH F; 
#chains in the Genus database with same CATH homology
 2H7Z A;  1F94 A;  1CHV S;  3QB4 B;  4RUD A;  2L5S A;  3KFD I;  1H0J A;  1NXB A;  3PLC A;  1IKC A;  1FSC A;  1FRA A;  2UWR A;  1CDS A;  1CRE A;  1I02 A;  1L4W A;  6EBX A;  3BT1 U;  5IMT D;  2CCX A;  4BIK B;  4KSN A;  1TGX A;  3KFD E;  2ABX A;  4QTI U;  1LJZ A;  1CDR A;  1CTX A;  1YWH A;  4OM4 A;  1NTX A;  3EBX A;  1ES7 B;  2BTX A;  1IQ9 A;  4ZQY A;  1NTN A;  1TXB A;  3FEV A;  4BDT B;  1CCQ A;  1FSS B;  4AEA A;  4P7U A;  1CRF A;  1QKD A;  3ERA A;  2UX2 A;  1IDH A;  1TXA A;  2ERA A;  2FD6 U;  1RL5 A;  1BTE A;  4FAO C;  4HQP F;  1ABT A;  3LAQ U;  2MJ4 A;  1XT3 A;  2X8B B;  1FFJ A;  3U73 U;  1S4Y A;  4EY8 B;  1COE A;  2VLW A;  1KBA A;  2OFS A;  1RGJ A;  1KFH A;  1COD A;  1HC9 B;  1TFS A;  1NEA A;  3NH7 A;  1KU6 B;  4XJJ A;  2GOO B;  1KTZ B;  1DRS A;  2HLR A;  4FAO E;  4UY2 C;  2HLQ A;  5DZ5 A;  5DO6 A;  2QJB C;  4IYE A;  1HAJ A;  2K3G A;  1BXP A;  1NYS A;  1HC9 A;  1MR6 A;  3U74 U;  1W6B A;  1CVO A;  1LX5 B;  5EBX A;  1JBD A;  1NYU A;  1NOR A;  4DO8 A;  1V6P A;  2PJY B;  1HOY A;  5DU1 A;  2JQP A;  1KXI A;  2H62 D;  2MJ0 A;  1IDL A;  1JGK A;  5IMY C;  2QC1 A;  2BHI A;  1ONJ A;  1QKE A;  1IDG A;  2L03 A;  4LFT A;  1KS6 A;  1UG4 A;  1FF4 A;  3HH7 A;  2MHY A;  3EVS C;  1LXH A;  1M9Z A;  2H62 C;  1REW C;  3BT2 U;  2CRS A;  1ERA A;  2H64 B;  2LA1 A;  2MUO A;  2PJY C;  2LCR A;  4OM5 A;  1PLO A;  1B41 B;  2I9B E;  1KL8 A;  2QJA C;  1CXN A;  1KBS A;  1IJC A;  1KC4 A;  2MJY A;  1LSI A;  1QM7 A;  2CTX A;  1FAS A;  2CRT A;  1ZAD A;  1CDT A;  1CDQ A;  2GOO C;  2J8B A;  2MFA A;  2CDX A;  2N99 A;  2NBT A;  1LXG A;  3NEQ A;  2H7Z B;  1F8U B;  2H64 C;  1IDI A;  1KBT A;  2H5F A;  3VTS A;  1CXO A;  2H8U A;  2MUP A;  1HAA A;  1VB0 A;  1CB9 A;  1G6M A;  3NDS A;  1IK8 A;  1ERG A;  2JVE A;  2QJ9 C;  1JE9 A;  1MAH F; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...