4ZQYA

Ringhalexin from hemachatus haemachatus: a novel inhibitor of extrinsic tenase complex
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
65
structure length
65
Chain Sequence
RLCLSDYSIFSETIEICPEGHNYCFKKFPKGITRLPWVIRGCAATCPKPEAQVYVDCCARDKCNR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Ringhalexin from Hemachatus haemachatus: A novel inhibitor of extrinsic tenase complex.
pubmed doi rcsb
molecule tags Toxin
molecule keywords Ringhalexin
total genus 11
structure length 65
sequence length 65
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2015-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00087 Toxin_TOLIP Snake toxin and toxin-like protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 4zqyA00
4FAOC 2QC1A 1NYSA 4BDTB 2LA1A 1KBAA 1HAAA 2VLWA 2CTXA 2MHYA 4P7UA 2CCXA 1CODA 2QJAC 1L4WA 2H64B 1FSSB 2GOOC 1CDTA 4QTIU 4ZQYA 1IDHA 5EBXA 1KS6A 1IJCA 3U74U 1CREA 5DU1A 1CB9A 2CRTA 1CHVS 1FASA 1QKDA 1YWHA 1LJZA 3KFDE 2GOOB 3FEVA 4LFTA 1KBSA 1RL5A 2L03A 1NXBA 2H5FA 1KL8A 3NDSA 1V6PA 1NORA 1ONJA 2HLRA 2MUPA 4FAOE 1F94A 2X8BB 2QJ9C 2H62D 1B41B 2MJ0A 2N99A 1I02A 3U73U 2PJYC 2H7ZA 1IKCA 1NTXA 3BT2U 1HOYA 1CXOA 4AEAA 1IK8A 4HQPF 4UY2C 3PLCA 4XJJA 1ZADA 1LXGA 1NEAA 1KBTA 2CRSA 1CCQA 1IQ9A 1NYUA 2J8BA 2MJYA 4IYEA 1KFHA 1UG4A 1IDIA 1KU6B 2H7ZB 2PJYB 1FRAA 1CTXA 1CDQA 2MUOA 1FF4A 3NH7A 1JGKA 2UX2A 5IMTD 2CDXA 1DRSA 4RUDA 1LSIA 1HC9A 1IDGA 1MAHF 1TXBA 3EBXA 2H62C 5DO6A 3ERAA 1FSCA 1W6BA 1KXIA 2HLQA 4EY8B 1JBDA 1TXAA 2K3GA 3QB4B 1BXPA 1COEA 1HAJA 2H64C 6EBXA 2MJ4A 4OM4A 2QJBC 1KC4A 4OM5A 1FFJA 1QM7A 1HC9B 3NEQA 4BIKB 1XT3A 1ERGA 1VB0A 1S4YA 3VTSA 1TGXA 1TFSA 2BHIA 1G6MA 2NBTA 1LX5B 1CVOA 1KTZB 2JQPA 1LXHA 1REWC 1CRFA 1MR6A 2FD6U 3KFDI 1IDLA 2I9BE 1CXNA 2OFSA 3EVSC 2BTXA 2ABXA 4DO8A 5DZ5A 2UWRA 1JE9A 1RGJA 2H8UA 3HH7A 1NTNA 1ABTA 1BTEA 2JVEA 2MFAA 1CDSA 3BT1U 1ERAA 1CDRA 1M9ZA 3LAQU 2L5SA 1F8UB 1ES7B 5IMYC 1QKEA 2LCRA 1PLOA 1H0JA 2ERAA
chains in the Genus database with same CATH superfamily
4FAOC 2QC1A 1NYSA 4BDTB 2LA1A 1KBAA 1HAAA 2VLWA 2CTXA 2MHYA 4P7UA 2CCXA 1CODA 2QJAC 1L4WA 2H64B 1FSSB 2GOOC 1CDTA 4QTIU 4ZQYA 1IDHA 5EBXA 1KS6A 1IJCA 3U74U 1CREA 5DU1A 1CB9A 2CRTA 1CHVS 1FASA 1QKDA 1YWHA 1LJZA 3KFDE 2GOOB 3FEVA 4LFTA 1KBSA 1RL5A 2L03A 1NXBA 2H5FA 1KL8A 3NDSA 1V6PA 1NORA 1ONJA 2HLRA 2MUPA 4FAOE 1F94A 2X8BB 2QJ9C 2H62D 1B41B 2MJ0A 2N99A 1I02A 3U73U 2PJYC 2H7ZA 1IKCA 1NTXA 3BT2U 1HOYA 1CXOA 4AEAA 1IK8A 4HQPF 4UY2C 3PLCA 4XJJA 1ZADA 1LXGA 1NEAA 1KBTA 2CRSA 1CCQA 1IQ9A 1NYUA 2J8BA 2MJYA 4IYEA 1KFHA 1UG4A 1IDIA 1KU6B 2H7ZB 2PJYB 1FRAA 1CTXA 1CDQA 2MUOA 1FF4A 3NH7A 1JGKA 2UX2A 5IMTD 2CDXA 1DRSA 4RUDA 1LSIA 1HC9A 1IDGA 1MAHF 1TXBA 3EBXA 2H62C 5DO6A 3ERAA 1FSCA 1W6BA 1KXIA 2HLQA 4EY8B 1JBDA 1TXAA 2K3GA 3QB4B 1BXPA 1COEA 1HAJA 2H64C 6EBXA 2MJ4A 4OM4A 2QJBC 1KC4A 4OM5A 1FFJA 1QM7A 1HC9B 3NEQA 4BIKB 1XT3A 1ERGA 1VB0A 1S4YA 3VTSA 1TGXA 1TFSA 2BHIA 1G6MA 2NBTA 1LX5B 1CVOA 1KTZB 2JQPA 1LXHA 1REWC 1CRFA 1MR6A 2FD6U 4KSNA 3KFDI 1IDLA 2I9BE 1CXNA 2OFSA 3EVSC 2BTXA 2ABXA 4DO8A 5DZ5A 2UWRA 1JE9A 1RGJA 2H8UA 3HH7A 1NTNA 1ABTA 1BTEA 2JVEA 2MFAA 1CDSA 3BT1U 1ERAA 1CDRA 1M9ZA 3LAQU 2L5SA 1F8UB 1ES7B 5IMYC 1QKEA 2LCRA 1PLOA 1H0JA 2ERAA
chains in the Genus database with same CATH topology
4FAOC 2QC1A 1NYSA 4BDTB 2LA1A 1KBAA 1HAAA 2VLWA 2CTXA 2MHYA 4P7UA 2CCXA 1CODA 2QJAC 1L4WA 2H64B 1FSSB 2GOOC 1CDTA 4QTIU 4ZQYA 1IDHA 5EBXA 1KS6A 1IJCA 3U74U 1CREA 5DU1A 1CB9A 2CRTA 1CHVS 1FASA 1QKDA 1YWHA 1LJZA 3KFDE 2GOOB 3FEVA 4LFTA 1KBSA 1RL5A 2L03A 1NXBA 2H5FA 1KL8A 3NDSA 1V6PA 1NORA 1ONJA 2HLRA 2MUPA 4FAOE 1F94A 2X8BB 2QJ9C 2H62D 1B41B 2MJ0A 2N99A 1I02A 3U73U 2PJYC 2H7ZA 1IKCA 1NTXA 3BT2U 1HOYA 1CXOA 4AEAA 1IK8A 4HQPF 4UY2C 3PLCA 4XJJA 1ZADA 1LXGA 1NEAA 1KBTA 2CRSA 1CCQA 1IQ9A 1NYUA 2J8BA 2MJYA 4IYEA 1KFHA 1UG4A 1IDIA 1KU6B 2H7ZB 2PJYB 1FRAA 1CTXA 1CDQA 2MUOA 1FF4A 3NH7A 1JGKA 2UX2A 5IMTD 2CDXA 1DRSA 4RUDA 1LSIA 1HC9A 1IDGA 1MAHF 1TXBA 3EBXA 2H62C 5DO6A 3ERAA 1FSCA 1W6BA 1KXIA 2HLQA 4EY8B 1JBDA 1TXAA 2K3GA 3QB4B 1BXPA 1COEA 1HAJA 2H64C 6EBXA 2MJ4A 4OM4A 2QJBC 1KC4A 4OM5A 1FFJA 1QM7A 1HC9B 3NEQA 4BIKB 1XT3A 1ERGA 1VB0A 1S4YA 3VTSA 1TGXA 1TFSA 2BHIA 1G6MA 2NBTA 1LX5B 1CVOA 1KTZB 2JQPA 1LXHA 1REWC 1CRFA 1MR6A 2FD6U 4KSNA 3KFDI 1IDLA 2I9BE 1CXNA 2OFSA 3EVSC 2BTXA 2ABXA 4DO8A 5DZ5A 2UWRA 1JE9A 1RGJA 2H8UA 3HH7A 1NTNA 1ABTA 1BTEA 2JVEA 2MFAA 1CDSA 3BT1U 1ERAA 1CDRA 1M9ZA 3LAQU 2L5SA 1F8UB 1ES7B 5IMYC 1QKEA 2LCRA 1PLOA 1H0JA 2ERAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FAO C;  2QC1 A;  1NYS A;  4BDT B;  2LA1 A;  1KBA A;  1HAA A;  2VLW A;  2CTX A;  2MHY A;  4P7U A;  2CCX A;  1COD A;  2QJA C;  1L4W A;  2H64 B;  1FSS B;  2GOO C;  1CDT A;  4QTI U;  4ZQY A;  1IDH A;  5EBX A;  1KS6 A;  1IJC A;  3U74 U;  1CRE A;  5DU1 A;  1CB9 A;  2CRT A;  1CHV S;  1FAS A;  1QKD A;  1YWH A;  1LJZ A;  3KFD E;  2GOO B;  3FEV A;  4LFT A;  1KBS A;  1RL5 A;  2L03 A;  1NXB A;  2H5F A;  1KL8 A;  3NDS A;  1V6P A;  1NOR A;  1ONJ A;  2HLR A;  2MUP A;  4FAO E;  1F94 A;  2X8B B;  2QJ9 C;  2H62 D;  1B41 B;  2MJ0 A;  2N99 A;  1I02 A;  3U73 U;  2PJY C;  2H7Z A;  1IKC A;  1NTX A;  3BT2 U;  1HOY A;  1CXO A;  4AEA A;  1IK8 A;  4HQP F;  4UY2 C;  3PLC A;  4XJJ A;  1ZAD A;  1LXG A;  1NEA A;  1KBT A;  2CRS A;  1CCQ A;  1IQ9 A;  1NYU A;  2J8B A;  2MJY A;  4IYE A;  1KFH A;  1UG4 A;  1IDI A;  1KU6 B;  2H7Z B;  2PJY B;  1FRA A;  1CTX A;  1CDQ A;  2MUO A;  1FF4 A;  3NH7 A;  1JGK A;  2UX2 A;  5IMT D;  2CDX A;  1DRS A;  4RUD A;  1LSI A;  1HC9 A;  1IDG A;  1MAH F;  1TXB A;  3EBX A;  2H62 C;  5DO6 A;  3ERA A;  1FSC A;  1W6B A;  1KXI A;  2HLQ A;  4EY8 B;  1JBD A;  1TXA A;  2K3G A;  3QB4 B;  1BXP A;  1COE A;  1HAJ A;  2H64 C;  6EBX A;  2MJ4 A;  4OM4 A;  2QJB C;  1KC4 A;  4OM5 A;  1FFJ A;  1QM7 A;  1HC9 B;  3NEQ A;  4BIK B;  1XT3 A;  1ERG A;  1VB0 A;  1S4Y A;  3VTS A;  1TGX A;  1TFS A;  2BHI A;  1G6M A;  2NBT A;  1LX5 B;  1CVO A;  1KTZ B;  2JQP A;  1LXH A;  1REW C;  1CRF A;  1MR6 A;  2FD6 U;  3KFD I;  1IDL A;  2I9B E;  1CXN A;  2OFS A;  3EVS C;  2BTX A;  2ABX A;  4DO8 A;  5DZ5 A;  2UWR A;  1JE9 A;  1RGJ A;  2H8U A;  3HH7 A;  1NTN A;  1ABT A;  1BTE A;  2JVE A;  2MFA A;  1CDS A;  3BT1 U;  1ERA A;  1CDR A;  1M9Z A;  3LAQ U;  2L5S A;  1F8U B;  1ES7 B;  5IMY C;  1QKE A;  2LCR A;  1PLO A;  1H0J A;  2ERA A; 
#chains in the Genus database with same CATH topology
 4FAO C;  2QC1 A;  1NYS A;  4BDT B;  2LA1 A;  1KBA A;  1HAA A;  2VLW A;  2CTX A;  2MHY A;  4P7U A;  2CCX A;  1COD A;  2QJA C;  1L4W A;  2H64 B;  1FSS B;  2GOO C;  1CDT A;  4QTI U;  4ZQY A;  1IDH A;  5EBX A;  1KS6 A;  1IJC A;  3U74 U;  1CRE A;  5DU1 A;  1CB9 A;  2CRT A;  1CHV S;  1FAS A;  1QKD A;  1YWH A;  1LJZ A;  3KFD E;  2GOO B;  3FEV A;  4LFT A;  1KBS A;  1RL5 A;  2L03 A;  1NXB A;  2H5F A;  1KL8 A;  3NDS A;  1V6P A;  1NOR A;  1ONJ A;  2HLR A;  2MUP A;  4FAO E;  1F94 A;  2X8B B;  2QJ9 C;  2H62 D;  1B41 B;  2MJ0 A;  2N99 A;  1I02 A;  3U73 U;  2PJY C;  2H7Z A;  1IKC A;  1NTX A;  3BT2 U;  1HOY A;  1CXO A;  4AEA A;  1IK8 A;  4HQP F;  4UY2 C;  3PLC A;  4XJJ A;  1ZAD A;  1LXG A;  1NEA A;  1KBT A;  2CRS A;  1CCQ A;  1IQ9 A;  1NYU A;  2J8B A;  2MJY A;  4IYE A;  1KFH A;  1UG4 A;  1IDI A;  1KU6 B;  2H7Z B;  2PJY B;  1FRA A;  1CTX A;  1CDQ A;  2MUO A;  1FF4 A;  3NH7 A;  1JGK A;  2UX2 A;  5IMT D;  2CDX A;  1DRS A;  4RUD A;  1LSI A;  1HC9 A;  1IDG A;  1MAH F;  1TXB A;  3EBX A;  2H62 C;  5DO6 A;  3ERA A;  1FSC A;  1W6B A;  1KXI A;  2HLQ A;  4EY8 B;  1JBD A;  1TXA A;  2K3G A;  3QB4 B;  1BXP A;  1COE A;  1HAJ A;  2H64 C;  6EBX A;  2MJ4 A;  4OM4 A;  2QJB C;  1KC4 A;  4OM5 A;  1FFJ A;  1QM7 A;  1HC9 B;  3NEQ A;  4BIK B;  1XT3 A;  1ERG A;  1VB0 A;  1S4Y A;  3VTS A;  1TGX A;  1TFS A;  2BHI A;  1G6M A;  2NBT A;  1LX5 B;  1CVO A;  1KTZ B;  2JQP A;  1LXH A;  1REW C;  1CRF A;  1MR6 A;  2FD6 U;  4KSN A;  3KFD I;  1IDL A;  2I9B E;  1CXN A;  2OFS A;  3EVS C;  2BTX A;  2ABX A;  4DO8 A;  5DZ5 A;  2UWR A;  1JE9 A;  1RGJ A;  2H8U A;  3HH7 A;  1NTN A;  1ABT A;  1BTE A;  2JVE A;  2MFA A;  1CDS A;  3BT1 U;  1ERA A;  1CDR A;  1M9Z A;  3LAQ U;  2L5S A;  1F8U B;  1ES7 B;  5IMY C;  1QKE A;  2LCR A;  1PLO A;  1H0J A;  2ERA A; 
#chains in the Genus database with same CATH homology
 4FAO C;  2QC1 A;  1NYS A;  4BDT B;  2LA1 A;  1KBA A;  1HAA A;  2VLW A;  2CTX A;  2MHY A;  4P7U A;  2CCX A;  1COD A;  2QJA C;  1L4W A;  2H64 B;  1FSS B;  2GOO C;  1CDT A;  4QTI U;  4ZQY A;  1IDH A;  5EBX A;  1KS6 A;  1IJC A;  3U74 U;  1CRE A;  5DU1 A;  1CB9 A;  2CRT A;  1CHV S;  1FAS A;  1QKD A;  1YWH A;  1LJZ A;  3KFD E;  2GOO B;  3FEV A;  4LFT A;  1KBS A;  1RL5 A;  2L03 A;  1NXB A;  2H5F A;  1KL8 A;  3NDS A;  1V6P A;  1NOR A;  1ONJ A;  2HLR A;  2MUP A;  4FAO E;  1F94 A;  2X8B B;  2QJ9 C;  2H62 D;  1B41 B;  2MJ0 A;  2N99 A;  1I02 A;  3U73 U;  2PJY C;  2H7Z A;  1IKC A;  1NTX A;  3BT2 U;  1HOY A;  1CXO A;  4AEA A;  1IK8 A;  4HQP F;  4UY2 C;  3PLC A;  4XJJ A;  1ZAD A;  1LXG A;  1NEA A;  1KBT A;  2CRS A;  1CCQ A;  1IQ9 A;  1NYU A;  2J8B A;  2MJY A;  4IYE A;  1KFH A;  1UG4 A;  1IDI A;  1KU6 B;  2H7Z B;  2PJY B;  1FRA A;  1CTX A;  1CDQ A;  2MUO A;  1FF4 A;  3NH7 A;  1JGK A;  2UX2 A;  5IMT D;  2CDX A;  1DRS A;  4RUD A;  1LSI A;  1HC9 A;  1IDG A;  1MAH F;  1TXB A;  3EBX A;  2H62 C;  5DO6 A;  3ERA A;  1FSC A;  1W6B A;  1KXI A;  2HLQ A;  4EY8 B;  1JBD A;  1TXA A;  2K3G A;  3QB4 B;  1BXP A;  1COE A;  1HAJ A;  2H64 C;  6EBX A;  2MJ4 A;  4OM4 A;  2QJB C;  1KC4 A;  4OM5 A;  1FFJ A;  1QM7 A;  1HC9 B;  3NEQ A;  4BIK B;  1XT3 A;  1ERG A;  1VB0 A;  1S4Y A;  3VTS A;  1TGX A;  1TFS A;  2BHI A;  1G6M A;  2NBT A;  1LX5 B;  1CVO A;  1KTZ B;  2JQP A;  1LXH A;  1REW C;  1CRF A;  1MR6 A;  2FD6 U;  4KSN A;  3KFD I;  1IDL A;  2I9B E;  1CXN A;  2OFS A;  3EVS C;  2BTX A;  2ABX A;  4DO8 A;  5DZ5 A;  2UWR A;  1JE9 A;  1RGJ A;  2H8U A;  3HH7 A;  1NTN A;  1ABT A;  1BTE A;  2JVE A;  2MFA A;  1CDS A;  3BT1 U;  1ERA A;  1CDR A;  1M9Z A;  3LAQ U;  2L5S A;  1F8U B;  1ES7 B;  5IMY C;  1QKE A;  2LCR A;  1PLO A;  1H0J A;  2ERA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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