4HQPF

Alpha7 nicotinic receptor chimera and its complex with alpha bungarotoxin
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
73
structure length
73
Chain Sequence
IVCHTTATSPISAVTCPPGENLCYRKMWCDVFCSSRGKVVELGCAATCPSKKPYEEVTCCSTDKCNPHPKQRP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Protein binding
source organism Homo sapiens, lymnaea stagnalis
publication title Structural principles for Alpha-neurotoxin binding to and selectivity among nicotinic receptors
rcsb
molecule keywords Alpha7 nicotinic receptor chimera
total genus 8
structure length 73
sequence length 73
chains with identical sequence G, H, I, J
ec nomenclature
pdb deposition date 2012-10-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00087 Toxin_TOLIP Snake toxin and toxin-like protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 4hqpF00
5DO6A 2H7ZB 2NBTA 3KFDE 1IDGA 2UWRA 4OM5A 2CRSA 1QM7A 4P7UA 1TXBA 2QJAC 2X8BB 1FFJA 1CCQA 3NH7A 2MJ0A 1XT3A 1NTNA 1S4YA 2L03A 4EY8B 2MFAA 1I02A 3EBXA 1RGJA 1YWHA 1CHVS 1RL5A 2H5FA 1FASA 4RUDA 1DRSA 2K3GA 1CREA 1PLOA 1ES7B 3BT1U 2MHYA 2HLRA 1LSIA 2N99A 2H64B 1FSSB 4UY2C 1IDHA 1H0JA 2H64C 1FRAA 3QB4B 3ERAA 1KBTA 1L4WA 1BTEA 1IDLA 1KFHA 2CRTA 2VLWA 2H8UA 1CODA 2UX2A 1JE9A 1MR6A 2MJ4A 1NYUA 2CCXA 2QC1A 1HOYA 1HAJA 1LXGA 1FSCA 1HC9A 1IK8A 1KU6B 3FEVA 1CXOA 1IJCA 1CDTA 4ZQYA 3U74U 1NYSA 1REWC 3NDSA 1MAHF 1ZADA 1ERGA 5IMYC 1KL8A 2CTXA 2JVEA 1JBDA 2L5SA 1HC9B 3LAQU 3U73U 1LJZA 1FF4A 2FD6U 1IKCA 5EBXA 1NORA 1QKEA 4HQPF 1B41B 2JQPA 1KTZB 4BDTB 4FAOE 1CB9A 4OM4A 1ONJA 1KXIA 1NTXA 2LA1A 2QJ9C 4BIKB 4FAOC 2ABXA 1NEAA 1JGKA 2MUOA 1KC4A 1KBAA 4XJJA 1KBSA 5IMTD 1NXBA 1LX5B 1LXHA 2I9BE 4IYEA 1TFSA 2QJBC 2MUPA 1W6BA 1TXAA 2GOOB 1CVOA 1ABTA 3EVSC 2GOOC 3VTSA 1CRFA 2LCRA 1F8UB 2OFSA 4LFTA 2H62D 5DU1A 1ERAA 2H7ZA 3PLCA 1HAAA 1TGXA 1G6MA 1VB0A 3KFDI 1F94A 3NEQA 1IDIA 3HH7A 2MJYA 1CDSA 5DZ5A 1CDQA 1COEA 1KS6A 2BTXA 4AEAA 1CTXA 1CDRA 2PJYB 1UG4A 1QKDA 1V6PA 2H62C 2ERAA 2CDXA 6EBXA 2J8BA 2BHIA 3BT2U 1BXPA 2PJYC 4DO8A 2HLQA 1CXNA 1IQ9A 4QTIU 1M9ZA
chains in the Genus database with same CATH superfamily
5DO6A 2H7ZB 2NBTA 3KFDE 1IDGA 2UWRA 4OM5A 2CRSA 1QM7A 4P7UA 1TXBA 2QJAC 2X8BB 1FFJA 1CCQA 3NH7A 2MJ0A 1XT3A 1NTNA 1S4YA 2L03A 4EY8B 2MFAA 1I02A 3EBXA 1RGJA 1YWHA 1CHVS 1RL5A 2H5FA 1FASA 4RUDA 1DRSA 2K3GA 1CREA 1PLOA 1ES7B 3BT1U 2MHYA 2HLRA 1LSIA 2N99A 2H64B 1FSSB 4UY2C 1IDHA 1H0JA 2H64C 1FRAA 3QB4B 3ERAA 1KBTA 1L4WA 1BTEA 1IDLA 1KFHA 2CRTA 2VLWA 2H8UA 1CODA 2UX2A 1JE9A 1MR6A 2MJ4A 4KSNA 1NYUA 2CCXA 2QC1A 1HOYA 1HAJA 1LXGA 1FSCA 1HC9A 1IK8A 1KU6B 3FEVA 1CXOA 1IJCA 1CDTA 4ZQYA 3U74U 1NYSA 1REWC 3NDSA 1MAHF 1ZADA 1ERGA 5IMYC 1KL8A 2CTXA 2JVEA 1JBDA 2L5SA 1HC9B 3LAQU 3U73U 1LJZA 1FF4A 2FD6U 1IKCA 5EBXA 1NORA 1QKEA 4HQPF 1B41B 2JQPA 1KTZB 4BDTB 4FAOE 1CB9A 4OM4A 1ONJA 1KXIA 1NTXA 2LA1A 2QJ9C 4BIKB 4FAOC 2ABXA 1NEAA 1JGKA 2MUOA 1KC4A 1KBAA 4XJJA 1KBSA 5IMTD 1NXBA 1LX5B 1LXHA 2I9BE 4IYEA 1TFSA 2QJBC 2MUPA 1W6BA 1TXAA 2GOOB 1CVOA 1ABTA 3EVSC 2GOOC 3VTSA 1CRFA 2LCRA 1F8UB 2OFSA 4LFTA 2H62D 5DU1A 1ERAA 2H7ZA 3PLCA 1HAAA 1TGXA 1G6MA 1VB0A 3KFDI 1F94A 3NEQA 1IDIA 3HH7A 2MJYA 1CDSA 5DZ5A 1CDQA 1COEA 1KS6A 2BTXA 4AEAA 1CTXA 1CDRA 2PJYB 1UG4A 1QKDA 1V6PA 2H62C 2ERAA 2CDXA 6EBXA 2J8BA 2BHIA 3BT2U 1BXPA 2PJYC 4DO8A 2HLQA 1CXNA 1IQ9A 4QTIU 1M9ZA
chains in the Genus database with same CATH topology
5DO6A 2H7ZB 2NBTA 3KFDE 1IDGA 2UWRA 4OM5A 2CRSA 1QM7A 4P7UA 1TXBA 2QJAC 2X8BB 1FFJA 1CCQA 3NH7A 2MJ0A 1XT3A 1NTNA 1S4YA 2L03A 4EY8B 2MFAA 1I02A 3EBXA 1RGJA 1YWHA 1CHVS 1RL5A 2H5FA 1FASA 4RUDA 1DRSA 2K3GA 1CREA 1PLOA 1ES7B 3BT1U 2MHYA 2HLRA 1LSIA 2N99A 2H64B 1FSSB 4UY2C 1IDHA 1H0JA 2H64C 1FRAA 3QB4B 3ERAA 1KBTA 1L4WA 1BTEA 1IDLA 1KFHA 2CRTA 2VLWA 2H8UA 1CODA 2UX2A 1JE9A 1MR6A 2MJ4A 4KSNA 1NYUA 2CCXA 2QC1A 1HOYA 1HAJA 1LXGA 1FSCA 1HC9A 1IK8A 1KU6B 3FEVA 1CXOA 1IJCA 1CDTA 4ZQYA 3U74U 1NYSA 1REWC 3NDSA 1MAHF 1ZADA 1ERGA 5IMYC 1KL8A 2CTXA 2JVEA 1JBDA 2L5SA 1HC9B 3LAQU 3U73U 1LJZA 1FF4A 2FD6U 1IKCA 5EBXA 1NORA 1QKEA 4HQPF 1B41B 2JQPA 1KTZB 4BDTB 4FAOE 1CB9A 4OM4A 1ONJA 1KXIA 1NTXA 2LA1A 2QJ9C 4BIKB 4FAOC 2ABXA 1NEAA 1JGKA 2MUOA 1KC4A 1KBAA 4XJJA 1KBSA 5IMTD 1NXBA 1LX5B 1LXHA 2I9BE 4IYEA 1TFSA 2QJBC 2MUPA 1W6BA 1TXAA 2GOOB 1CVOA 1ABTA 3EVSC 2GOOC 3VTSA 1CRFA 2LCRA 1F8UB 2OFSA 4LFTA 2H62D 5DU1A 1ERAA 2H7ZA 3PLCA 1HAAA 1TGXA 1G6MA 1VB0A 3KFDI 1F94A 3NEQA 1IDIA 3HH7A 2MJYA 1CDSA 5DZ5A 1CDQA 1COEA 1KS6A 2BTXA 4AEAA 1CTXA 1CDRA 2PJYB 1UG4A 1QKDA 1V6PA 2H62C 2ERAA 2CDXA 6EBXA 2J8BA 2BHIA 3BT2U 1BXPA 2PJYC 4DO8A 2HLQA 1CXNA 1IQ9A 4QTIU 1M9ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DO6 A;  2H7Z B;  2NBT A;  3KFD E;  1IDG A;  2UWR A;  4OM5 A;  2CRS A;  1QM7 A;  4P7U A;  1TXB A;  2QJA C;  2X8B B;  1FFJ A;  1CCQ A;  3NH7 A;  2MJ0 A;  1XT3 A;  1NTN A;  1S4Y A;  2L03 A;  4EY8 B;  2MFA A;  1I02 A;  3EBX A;  1RGJ A;  1YWH A;  1CHV S;  1RL5 A;  2H5F A;  1FAS A;  4RUD A;  1DRS A;  2K3G A;  1CRE A;  1PLO A;  1ES7 B;  3BT1 U;  2MHY A;  2HLR A;  1LSI A;  2N99 A;  2H64 B;  1FSS B;  4UY2 C;  1IDH A;  1H0J A;  2H64 C;  1FRA A;  3QB4 B;  3ERA A;  1KBT A;  1L4W A;  1BTE A;  1IDL A;  1KFH A;  2CRT A;  2VLW A;  2H8U A;  1COD A;  2UX2 A;  1JE9 A;  1MR6 A;  2MJ4 A;  1NYU A;  2CCX A;  2QC1 A;  1HOY A;  1HAJ A;  1LXG A;  1FSC A;  1HC9 A;  1IK8 A;  1KU6 B;  3FEV A;  1CXO A;  1IJC A;  1CDT A;  4ZQY A;  3U74 U;  1NYS A;  1REW C;  3NDS A;  1MAH F;  1ZAD A;  1ERG A;  5IMY C;  1KL8 A;  2CTX A;  2JVE A;  1JBD A;  2L5S A;  1HC9 B;  3LAQ U;  3U73 U;  1LJZ A;  1FF4 A;  2FD6 U;  1IKC A;  5EBX A;  1NOR A;  1QKE A;  4HQP F;  1B41 B;  2JQP A;  1KTZ B;  4BDT B;  4FAO E;  1CB9 A;  4OM4 A;  1ONJ A;  1KXI A;  1NTX A;  2LA1 A;  2QJ9 C;  4BIK B;  4FAO C;  2ABX A;  1NEA A;  1JGK A;  2MUO A;  1KC4 A;  1KBA A;  4XJJ A;  1KBS A;  5IMT D;  1NXB A;  1LX5 B;  1LXH A;  2I9B E;  4IYE A;  1TFS A;  2QJB C;  2MUP A;  1W6B A;  1TXA A;  2GOO B;  1CVO A;  1ABT A;  3EVS C;  2GOO C;  3VTS A;  1CRF A;  2LCR A;  1F8U B;  2OFS A;  4LFT A;  2H62 D;  5DU1 A;  1ERA A;  2H7Z A;  3PLC A;  1HAA A;  1TGX A;  1G6M A;  1VB0 A;  3KFD I;  1F94 A;  3NEQ A;  1IDI A;  3HH7 A;  2MJY A;  1CDS A;  5DZ5 A;  1CDQ A;  1COE A;  1KS6 A;  2BTX A;  4AEA A;  1CTX A;  1CDR A;  2PJY B;  1UG4 A;  1QKD A;  1V6P A;  2H62 C;  2ERA A;  2CDX A;  6EBX A;  2J8B A;  2BHI A;  3BT2 U;  1BXP A;  2PJY C;  4DO8 A;  2HLQ A;  1CXN A;  1IQ9 A;  4QTI U;  1M9Z A; 
#chains in the Genus database with same CATH topology
 5DO6 A;  2H7Z B;  2NBT A;  3KFD E;  1IDG A;  2UWR A;  4OM5 A;  2CRS A;  1QM7 A;  4P7U A;  1TXB A;  2QJA C;  2X8B B;  1FFJ A;  1CCQ A;  3NH7 A;  2MJ0 A;  1XT3 A;  1NTN A;  1S4Y A;  2L03 A;  4EY8 B;  2MFA A;  1I02 A;  3EBX A;  1RGJ A;  1YWH A;  1CHV S;  1RL5 A;  2H5F A;  1FAS A;  4RUD A;  1DRS A;  2K3G A;  1CRE A;  1PLO A;  1ES7 B;  3BT1 U;  2MHY A;  2HLR A;  1LSI A;  2N99 A;  2H64 B;  1FSS B;  4UY2 C;  1IDH A;  1H0J A;  2H64 C;  1FRA A;  3QB4 B;  3ERA A;  1KBT A;  1L4W A;  1BTE A;  1IDL A;  1KFH A;  2CRT A;  2VLW A;  2H8U A;  1COD A;  2UX2 A;  1JE9 A;  1MR6 A;  2MJ4 A;  4KSN A;  1NYU A;  2CCX A;  2QC1 A;  1HOY A;  1HAJ A;  1LXG A;  1FSC A;  1HC9 A;  1IK8 A;  1KU6 B;  3FEV A;  1CXO A;  1IJC A;  1CDT A;  4ZQY A;  3U74 U;  1NYS A;  1REW C;  3NDS A;  1MAH F;  1ZAD A;  1ERG A;  5IMY C;  1KL8 A;  2CTX A;  2JVE A;  1JBD A;  2L5S A;  1HC9 B;  3LAQ U;  3U73 U;  1LJZ A;  1FF4 A;  2FD6 U;  1IKC A;  5EBX A;  1NOR A;  1QKE A;  4HQP F;  1B41 B;  2JQP A;  1KTZ B;  4BDT B;  4FAO E;  1CB9 A;  4OM4 A;  1ONJ A;  1KXI A;  1NTX A;  2LA1 A;  2QJ9 C;  4BIK B;  4FAO C;  2ABX A;  1NEA A;  1JGK A;  2MUO A;  1KC4 A;  1KBA A;  4XJJ A;  1KBS A;  5IMT D;  1NXB A;  1LX5 B;  1LXH A;  2I9B E;  4IYE A;  1TFS A;  2QJB C;  2MUP A;  1W6B A;  1TXA A;  2GOO B;  1CVO A;  1ABT A;  3EVS C;  2GOO C;  3VTS A;  1CRF A;  2LCR A;  1F8U B;  2OFS A;  4LFT A;  2H62 D;  5DU1 A;  1ERA A;  2H7Z A;  3PLC A;  1HAA A;  1TGX A;  1G6M A;  1VB0 A;  3KFD I;  1F94 A;  3NEQ A;  1IDI A;  3HH7 A;  2MJY A;  1CDS A;  5DZ5 A;  1CDQ A;  1COE A;  1KS6 A;  2BTX A;  4AEA A;  1CTX A;  1CDR A;  2PJY B;  1UG4 A;  1QKD A;  1V6P A;  2H62 C;  2ERA A;  2CDX A;  6EBX A;  2J8B A;  2BHI A;  3BT2 U;  1BXP A;  2PJY C;  4DO8 A;  2HLQ A;  1CXN A;  1IQ9 A;  4QTI U;  1M9Z A; 
#chains in the Genus database with same CATH homology
 5DO6 A;  2H7Z B;  2NBT A;  3KFD E;  1IDG A;  2UWR A;  4OM5 A;  2CRS A;  1QM7 A;  4P7U A;  1TXB A;  2QJA C;  2X8B B;  1FFJ A;  1CCQ A;  3NH7 A;  2MJ0 A;  1XT3 A;  1NTN A;  1S4Y A;  2L03 A;  4EY8 B;  2MFA A;  1I02 A;  3EBX A;  1RGJ A;  1YWH A;  1CHV S;  1RL5 A;  2H5F A;  1FAS A;  4RUD A;  1DRS A;  2K3G A;  1CRE A;  1PLO A;  1ES7 B;  3BT1 U;  2MHY A;  2HLR A;  1LSI A;  2N99 A;  2H64 B;  1FSS B;  4UY2 C;  1IDH A;  1H0J A;  2H64 C;  1FRA A;  3QB4 B;  3ERA A;  1KBT A;  1L4W A;  1BTE A;  1IDL A;  1KFH A;  2CRT A;  2VLW A;  2H8U A;  1COD A;  2UX2 A;  1JE9 A;  1MR6 A;  2MJ4 A;  4KSN A;  1NYU A;  2CCX A;  2QC1 A;  1HOY A;  1HAJ A;  1LXG A;  1FSC A;  1HC9 A;  1IK8 A;  1KU6 B;  3FEV A;  1CXO A;  1IJC A;  1CDT A;  4ZQY A;  3U74 U;  1NYS A;  1REW C;  3NDS A;  1MAH F;  1ZAD A;  1ERG A;  5IMY C;  1KL8 A;  2CTX A;  2JVE A;  1JBD A;  2L5S A;  1HC9 B;  3LAQ U;  3U73 U;  1LJZ A;  1FF4 A;  2FD6 U;  1IKC A;  5EBX A;  1NOR A;  1QKE A;  4HQP F;  1B41 B;  2JQP A;  1KTZ B;  4BDT B;  4FAO E;  1CB9 A;  4OM4 A;  1ONJ A;  1KXI A;  1NTX A;  2LA1 A;  2QJ9 C;  4BIK B;  4FAO C;  2ABX A;  1NEA A;  1JGK A;  2MUO A;  1KC4 A;  1KBA A;  4XJJ A;  1KBS A;  5IMT D;  1NXB A;  1LX5 B;  1LXH A;  2I9B E;  4IYE A;  1TFS A;  2QJB C;  2MUP A;  1W6B A;  1TXA A;  2GOO B;  1CVO A;  1ABT A;  3EVS C;  2GOO C;  3VTS A;  1CRF A;  2LCR A;  1F8U B;  2OFS A;  4LFT A;  2H62 D;  5DU1 A;  1ERA A;  2H7Z A;  3PLC A;  1HAA A;  1TGX A;  1G6M A;  1VB0 A;  3KFD I;  1F94 A;  3NEQ A;  1IDI A;  3HH7 A;  2MJY A;  1CDS A;  5DZ5 A;  1CDQ A;  1COE A;  1KS6 A;  2BTX A;  4AEA A;  1CTX A;  1CDR A;  2PJY B;  1UG4 A;  1QKD A;  1V6P A;  2H62 C;  2ERA A;  2CDX A;  6EBX A;  2J8B A;  2BHI A;  3BT2 U;  1BXP A;  2PJY C;  4DO8 A;  2HLQ A;  1CXN A;  1IQ9 A;  4QTI U;  1M9Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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