The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
27
|
sequence length |
102
|
structure length |
102
|
Chain Sequence |
ALCKFCDVRFSTCDNQKSCMSNCSITSICEKPQEVCVAVWRKNDENITLETVCHDPKLPYHDFILEDAASPTCIMKEKKKPGETFFMCSCSSDECNDNIIFS
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
The non-detergent sulfobetaine-201 acts as a pharmacological chaperone to promote folding and crystallization of the type II TGF-beta receptor extracellular domain.
pubmed doi rcsb |
| molecule keywords |
TGF-beta receptor type-2
|
| molecule tags |
Signaling protein
|
| source organism |
Homo sapiens
|
| total genus |
27
|
| structure length |
102
|
| sequence length |
102
|
| ec nomenclature |
ec
2.7.11.30: Receptor protein serine/threonine kinase. |
| pdb deposition date | 2014-03-27 |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Beta | Ribbon | CD59 | CD59 |
#chains in the Genus database with same CATH superfamily 5IMY C; 2GOO B; 3VTS A; 5IMT D; 2UX2 A; 1FRA A; 2UWR A; 5DO6 A; 2MJY A; 1F8U B; 1KBT A; 4RUD A; 1CRF A; 1V6P A; 1MR6 A; 2H62 D; 1NOR A; 1HC9 A; 1HOY A; 1I02 A; 1QKE A; 2HLQ A; 4LFT A; 6EBX A; 4ZQY A; 1JE9 A; 1KU6 B; 1NTX A; 1BXP A; 2LCR A; 1IJC A; 1IQ9 A; 1QKD A; 4FAO C; 1YWH A; 2N99 A; 2QJ9 C; 1W6B A; 2H64 C; 1KTZ B; 2PJY C; 2OFS A; 1LX5 B; 1PLO A; 2ABX A; 2CRT A; 1TXB A; 4XJJ A; 1MAH F; 1VB0 A; 1IDH A; 1LXG A; 4P7U A; 1REW C; 4BDT B; 2GOO C; 2CRS A; 2MUP A; 1CDR A; 1ES7 B; 3LAQ U; 1NYU A; 4OM5 A; 1B41 B; 1COE A; 1IK8 A; 4OM4 A; 2QC1 A; 3BT2 U; 2BTX A; 4AEA A; 1IDG A; 1RL5 A; 3NDS A; 1IDI A; 1KFH A; 1KL8 A; 1NTN A; 2VLW A; 2H5F A; 2CTX A; 2H62 C; 2I9B E; 2L5S A; 1CCQ A; 2ERA A; 1CDT A; 1ERG A; 2MFA A; 2JVE A; 1TFS A; 1FAS A; 1CXN A; 1KS6 A; 1ONJ A; 2H7Z A; 1XT3 A; 3EVS C; 1ABT A; 1UG4 A; 2X8B B; 2H8U A; 1ERA A; 1CRE A; 1CXO A; 4BIK B; 1KXI A; 1CB9 A; 1ZAD A; 1QM7 A; 1BTE A; 2K3G A; 4QTI U; 1NXB A; 5DZ5 A; 1CDQ A; 1M9Z A; 1RGJ A; 3FEV A; 1S4Y A; 2MHY A; 1NEA A; 3EBX A; 1CTX A; 2J8B A; 3HH7 A; 3BT1 U; 3PLC A; 2L03 A; 2MJ0 A; 1JGK A; 2JQP A; 1FSS B; 1JBD A; 2FD6 U; 1HC9 B; 1COD A; 1L4W A; 2MUO A; 2QJA C; 2QJB C; 1CHV S; 1HAA A; 4IYE A; 3U73 U; 3KFD E; 1FFJ A; 1KBA A; 2CCX A; 5DU1 A; 5EBX A; 1CDS A; 3NH7 A; 1H0J A; 1NYS A; 1G6M A; 1KC4 A; 2HLR A; 3NEQ A; 1TXA A; 1FF4 A; 4EY8 B; 4HQP F; 2CDX A; 4UY2 C; 1F94 A; 2NBT A; 3QB4 B; 1LJZ A; 1FSC A; 2H7Z B; 1KBS A; 1LSI A; 4DO8 A; 3KFD I; 2MJ4 A; 2H64 B; 2BHI A; 2PJY B; 3U74 U; 1HAJ A; 3ERA A; 1TGX A; 2LA1 A; 1CVO A; 1IKC A; 1IDL A; 1LXH A; 1DRS A; 4FAO E; #chains in the Genus database with same CATH topology 5IMY C; 2GOO B; 3VTS A; 5IMT D; 2UX2 A; 1FRA A; 2UWR A; 5DO6 A; 2MJY A; 1F8U B; 1KBT A; 4RUD A; 1CRF A; 1V6P A; 1MR6 A; 2H62 D; 1NOR A; 1HC9 A; 1HOY A; 1I02 A; 1QKE A; 2HLQ A; 4LFT A; 6EBX A; 4ZQY A; 1JE9 A; 1KU6 B; 1NTX A; 1BXP A; 2LCR A; 1IJC A; 1IQ9 A; 1QKD A; 4FAO C; 1YWH A; 2N99 A; 2QJ9 C; 1W6B A; 2H64 C; 1KTZ B; 2PJY C; 2OFS A; 1LX5 B; 1PLO A; 2ABX A; 2CRT A; 1TXB A; 4XJJ A; 1MAH F; 1VB0 A; 1IDH A; 1LXG A; 4P7U A; 1REW C; 4BDT B; 2GOO C; 2CRS A; 2MUP A; 1CDR A; 1ES7 B; 3LAQ U; 1NYU A; 4OM5 A; 1B41 B; 1COE A; 1IK8 A; 4OM4 A; 2QC1 A; 3BT2 U; 2BTX A; 4AEA A; 1IDG A; 1RL5 A; 3NDS A; 1IDI A; 1KFH A; 1KL8 A; 1NTN A; 2VLW A; 2H5F A; 2CTX A; 2H62 C; 2I9B E; 2L5S A; 1CCQ A; 2ERA A; 1CDT A; 1ERG A; 2MFA A; 2JVE A; 1TFS A; 1FAS A; 1CXN A; 1KS6 A; 1ONJ A; 2H7Z A; 1XT3 A; 3EVS C; 1ABT A; 1UG4 A; 2X8B B; 2H8U A; 1ERA A; 1CRE A; 1CXO A; 4BIK B; 1KXI A; 1CB9 A; 1ZAD A; 1QM7 A; 1BTE A; 2K3G A; 4QTI U; 1NXB A; 5DZ5 A; 1CDQ A; 1M9Z A; 1RGJ A; 3FEV A; 1S4Y A; 2MHY A; 1NEA A; 3EBX A; 1CTX A; 2J8B A; 3HH7 A; 3BT1 U; 3PLC A; 2L03 A; 2MJ0 A; 1JGK A; 2JQP A; 1FSS B; 1JBD A; 2FD6 U; 1HC9 B; 1COD A; 1L4W A; 2MUO A; 2QJA C; 2QJB C; 1CHV S; 1HAA A; 4IYE A; 3U73 U; 3KFD E; 1FFJ A; 1KBA A; 2CCX A; 5DU1 A; 5EBX A; 1CDS A; 3NH7 A; 1H0J A; 1NYS A; 1G6M A; 1KC4 A; 2HLR A; 3NEQ A; 1TXA A; 1FF4 A; 4EY8 B; 4HQP F; 2CDX A; 4UY2 C; 1F94 A; 2NBT A; 3QB4 B; 1LJZ A; 1FSC A; 2H7Z B; 1KBS A; 4KSN A; 1LSI A; 4DO8 A; 3KFD I; 2MJ4 A; 2H64 B; 2BHI A; 2PJY B; 3U74 U; 1HAJ A; 3ERA A; 1TGX A; 2LA1 A; 1CVO A; 1IKC A; 1IDL A; 1LXH A; 1DRS A; 4FAO E; #chains in the Genus database with same CATH homology 5IMY C; 2GOO B; 3VTS A; 5IMT D; 2UX2 A; 1FRA A; 2UWR A; 5DO6 A; 2MJY A; 1F8U B; 1KBT A; 4RUD A; 1CRF A; 1V6P A; 1MR6 A; 2H62 D; 1NOR A; 1HC9 A; 1HOY A; 1I02 A; 1QKE A; 2HLQ A; 4LFT A; 6EBX A; 4ZQY A; 1JE9 A; 1KU6 B; 1NTX A; 1BXP A; 2LCR A; 1IJC A; 1IQ9 A; 1QKD A; 4FAO C; 1YWH A; 2N99 A; 2QJ9 C; 1W6B A; 2H64 C; 1KTZ B; 2PJY C; 2OFS A; 1LX5 B; 1PLO A; 2ABX A; 2CRT A; 1TXB A; 4XJJ A; 1MAH F; 1VB0 A; 1IDH A; 1LXG A; 4P7U A; 1REW C; 4BDT B; 2GOO C; 2CRS A; 2MUP A; 1CDR A; 1ES7 B; 3LAQ U; 1NYU A; 4OM5 A; 1B41 B; 1COE A; 1IK8 A; 4OM4 A; 2QC1 A; 3BT2 U; 2BTX A; 4AEA A; 1IDG A; 1RL5 A; 3NDS A; 1IDI A; 1KFH A; 1KL8 A; 1NTN A; 2VLW A; 2H5F A; 2CTX A; 2H62 C; 2I9B E; 2L5S A; 1CCQ A; 2ERA A; 1CDT A; 1ERG A; 2MFA A; 2JVE A; 1TFS A; 1FAS A; 1CXN A; 1KS6 A; 1ONJ A; 2H7Z A; 1XT3 A; 3EVS C; 1ABT A; 1UG4 A; 2X8B B; 2H8U A; 1ERA A; 1CRE A; 1CXO A; 4BIK B; 1KXI A; 1CB9 A; 1ZAD A; 1QM7 A; 1BTE A; 2K3G A; 4QTI U; 1NXB A; 5DZ5 A; 1CDQ A; 1M9Z A; 1RGJ A; 3FEV A; 1S4Y A; 2MHY A; 1NEA A; 3EBX A; 1CTX A; 2J8B A; 3HH7 A; 3BT1 U; 3PLC A; 2L03 A; 2MJ0 A; 1JGK A; 2JQP A; 1FSS B; 1JBD A; 2FD6 U; 1HC9 B; 1COD A; 1L4W A; 2MUO A; 2QJA C; 2QJB C; 1CHV S; 1HAA A; 4IYE A; 3U73 U; 3KFD E; 1FFJ A; 1KBA A; 2CCX A; 5DU1 A; 5EBX A; 1CDS A; 3NH7 A; 1H0J A; 1NYS A; 1G6M A; 1KC4 A; 2HLR A; 3NEQ A; 1TXA A; 1FF4 A; 4EY8 B; 4HQP F; 2CDX A; 4UY2 C; 1F94 A; 2NBT A; 3QB4 B; 1LJZ A; 1FSC A; 2H7Z B; 1KBS A; 4KSN A; 1LSI A; 4DO8 A; 3KFD I; 2MJ4 A; 2H64 B; 2BHI A; 2PJY B; 3U74 U; 1HAJ A; 3ERA A; 1TGX A; 2LA1 A; 1CVO A; 1IKC A; 1IDL A; 1LXH A; 1DRS A; 4FAO E;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
