5DO6A

Crystal structure of dendroaspis polylepis venom mambalgin-1 t23a mutant
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
57
structure length
57
Chain Sequence
LKCYQHGKVVTCHRDMKFCYHNAGMPFRNLKLILQGCSSSCSETENNKCCSTDRCNK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mambalgin-1 Pain-relieving Peptide, Stepwise Solid-phase Synthesis, Crystal Structure, and Functional Domain for Acid-sensing Ion Channel 1a Inhibition.
pubmed doi rcsb
molecule tags Toxin
molecule keywords Mambalgin-1
total genus 13
structure length 57
sequence length 57
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-09-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 5do6A00
3BT1U 4QTIU 4FAOC 2VLWA 1IDGA 2BHIA 6EBXA 2GOOC 1TGXA 1LXGA 1ES7B 2UWRA 2LA1A 1CREA 2MJYA 2QJAC 3PLCA 1I02A 1NYUA 1KBTA 1FSCA 1KU6B 5DU1A 1HC9B 2JVEA 2K3GA 1ZADA 1NTXA 1CB9A 3BT2U 1ABTA 1XT3A 1CCQA 5DO6A 1G6MA 1IDIA 1HAAA 5EBXA 3EVSC 1ONJA 1IKCA 5IMYC 1L4WA 1CRFA 1H0JA 1CODA 1LSIA 1NTNA 2CCXA 2H7ZB 1YWHA 1ERGA 2H64B 1KS6A 2NBTA 1UG4A 1TFSA 1TXAA 4HQPF 5IMTD 1NORA 2JQPA 4DO8A 1CDSA 1CVOA 3NEQA 3VTSA 2MFAA 5DZ5A 1CXOA 1MR6A 1FASA 1CDRA 1QKEA 2BTXA 2MHYA 4BDTB 2J8BA 3U73U 4RUDA 2ABXA 1KFHA 2L03A 1NXBA 2MUPA 2FD6U 1KXIA 2L5SA 2UX2A 1HAJA 4AEAA 2H62D 1W6BA 1LXHA 2I9BE 1IDHA 2CDXA 1LX5B 2QJ9C 1JE9A 3ERAA 1IQ9A 2H7ZA 2LCRA 3U74U 1KL8A 4P7UA 1KBAA 1FRAA 3LAQU 2GOOB 1REWC 2OFSA 1QKDA 1B41B 3QB4B 4OM5A 1BXPA 2MJ0A 2H5FA 1CTXA 1FSSB 2MJ4A 2PJYC 1RL5A 4XJJA 2QJBC 4IYEA 1ERAA 4EY8B 1RGJA 2H62C 4BIKB 2CRTA 3NH7A 1HC9A 2HLQA 3KFDI 1COEA 1S4YA 1KTZB 1QM7A 1JGKA 2CTXA 1F94A 3FEVA 1CDQA 2X8BB 2MUOA 1F8UB 4ZQYA 1CXNA 2H8UA 3KFDE 1KBSA 1NEAA 4LFTA 1PLOA 1TXBA 2N99A 3EBXA 1JBDA 1KC4A 1DRSA 4OM4A 4FAOE 3HH7A 2HLRA 3NDSA 1BTEA 1NYSA 2ERAA 1HOYA 2PJYB 1CDTA 1V6PA 1VB0A 2QC1A 1IDLA 2CRSA 1IJCA 1MAHF 1IK8A 4UY2C 1CHVS 1FFJA 1M9ZA 1FF4A 1LJZA 2H64C
chains in the Genus database with same CATH superfamily
3BT1U 4QTIU 4FAOC 2VLWA 1IDGA 2BHIA 6EBXA 2GOOC 1TGXA 1LXGA 1ES7B 2UWRA 2LA1A 1CREA 2MJYA 2QJAC 3PLCA 1I02A 1NYUA 1KBTA 1FSCA 1KU6B 5DU1A 1HC9B 2JVEA 2K3GA 1ZADA 1NTXA 1CB9A 3BT2U 4KSNA 1XT3A 1ABTA 1CCQA 5DO6A 1G6MA 1IDIA 1HAAA 5EBXA 3EVSC 1ONJA 1IKCA 5IMYC 1L4WA 1CRFA 1H0JA 1CODA 1LSIA 1NTNA 2CCXA 2H7ZB 1YWHA 1ERGA 2H64B 1KS6A 2NBTA 1UG4A 1TFSA 1TXAA 4HQPF 5IMTD 1NORA 2JQPA 4DO8A 1CDSA 1CVOA 3NEQA 3VTSA 2MFAA 5DZ5A 1CXOA 1MR6A 1FASA 1CDRA 1QKEA 2BTXA 2MHYA 4BDTB 2J8BA 3U73U 4RUDA 2ABXA 1KFHA 2L03A 1NXBA 2MUPA 2FD6U 1KXIA 2L5SA 2UX2A 1HAJA 4AEAA 2H62D 1W6BA 1LXHA 2I9BE 1IDHA 2CDXA 1LX5B 2QJ9C 1JE9A 3ERAA 1IQ9A 2H7ZA 2LCRA 3U74U 1KL8A 4P7UA 1KBAA 1FRAA 3LAQU 2GOOB 1REWC 2OFSA 1QKDA 1B41B 3QB4B 4OM5A 1BXPA 2MJ0A 2H5FA 1CTXA 1FSSB 2MJ4A 2PJYC 1RL5A 4XJJA 2QJBC 4IYEA 1ERAA 4EY8B 1RGJA 2H62C 4BIKB 2CRTA 3NH7A 1HC9A 2HLQA 3KFDI 1COEA 1S4YA 1KTZB 1QM7A 1JGKA 2CTXA 1F94A 3FEVA 1CDQA 2X8BB 2MUOA 1F8UB 4ZQYA 1CXNA 2H8UA 3KFDE 1KBSA 1NEAA 4LFTA 1PLOA 1TXBA 2N99A 3EBXA 1JBDA 1KC4A 1DRSA 4OM4A 4FAOE 3HH7A 2HLRA 3NDSA 1BTEA 1NYSA 2ERAA 1HOYA 2PJYB 1CDTA 1V6PA 1VB0A 2QC1A 1IDLA 2CRSA 1IJCA 1MAHF 1IK8A 4UY2C 1CHVS 1FFJA 1M9ZA 1FF4A 1LJZA 2H64C
chains in the Genus database with same CATH topology
3BT1U 4QTIU 4FAOC 2VLWA 1IDGA 2BHIA 6EBXA 2GOOC 1TGXA 1LXGA 1ES7B 2UWRA 2LA1A 1CREA 2MJYA 2QJAC 3PLCA 1I02A 1NYUA 1KBTA 1FSCA 1KU6B 5DU1A 1HC9B 2JVEA 2K3GA 1ZADA 1NTXA 1CB9A 3BT2U 4KSNA 1XT3A 1ABTA 1CCQA 5DO6A 1G6MA 1IDIA 1HAAA 5EBXA 3EVSC 1ONJA 1IKCA 5IMYC 1L4WA 1CRFA 1H0JA 1CODA 1LSIA 1NTNA 2CCXA 2H7ZB 1YWHA 1ERGA 2H64B 1KS6A 2NBTA 1UG4A 1TFSA 1TXAA 4HQPF 5IMTD 1NORA 2JQPA 4DO8A 1CDSA 1CVOA 3NEQA 3VTSA 2MFAA 5DZ5A 1CXOA 1MR6A 1FASA 1CDRA 1QKEA 2BTXA 2MHYA 4BDTB 2J8BA 3U73U 4RUDA 2ABXA 1KFHA 2L03A 1NXBA 2MUPA 2FD6U 1KXIA 2L5SA 2UX2A 1HAJA 4AEAA 2H62D 1W6BA 1LXHA 2I9BE 1IDHA 2CDXA 1LX5B 2QJ9C 1JE9A 3ERAA 1IQ9A 2H7ZA 2LCRA 3U74U 1KL8A 4P7UA 1KBAA 1FRAA 3LAQU 2GOOB 1REWC 2OFSA 1QKDA 1B41B 3QB4B 4OM5A 1BXPA 2MJ0A 2H5FA 1CTXA 1FSSB 2MJ4A 2PJYC 1RL5A 4XJJA 2QJBC 4IYEA 1ERAA 4EY8B 1RGJA 2H62C 4BIKB 2CRTA 3NH7A 1HC9A 2HLQA 3KFDI 1COEA 1S4YA 1KTZB 1QM7A 1JGKA 2CTXA 1F94A 3FEVA 1CDQA 2X8BB 2MUOA 1F8UB 4ZQYA 1CXNA 2H8UA 3KFDE 1KBSA 1NEAA 4LFTA 1PLOA 1TXBA 2N99A 3EBXA 1JBDA 1KC4A 1DRSA 4OM4A 4FAOE 3HH7A 2HLRA 3NDSA 1BTEA 1NYSA 2ERAA 1HOYA 2PJYB 1CDTA 1V6PA 1VB0A 2QC1A 1IDLA 2CRSA 1IJCA 1MAHF 1IK8A 4UY2C 1CHVS 1FFJA 1M9ZA 1FF4A 1LJZA 2H64C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BT1 U;  4QTI U;  4FAO C;  2VLW A;  1IDG A;  2BHI A;  6EBX A;  2GOO C;  1TGX A;  1LXG A;  1ES7 B;  2UWR A;  2LA1 A;  1CRE A;  2MJY A;  2QJA C;  3PLC A;  1I02 A;  1NYU A;  1KBT A;  1FSC A;  1KU6 B;  5DU1 A;  1HC9 B;  2JVE A;  2K3G A;  1ZAD A;  1NTX A;  1CB9 A;  3BT2 U;  1ABT A;  1XT3 A;  1CCQ A;  5DO6 A;  1G6M A;  1IDI A;  1HAA A;  5EBX A;  3EVS C;  1ONJ A;  1IKC A;  5IMY C;  1L4W A;  1CRF A;  1H0J A;  1COD A;  1LSI A;  1NTN A;  2CCX A;  2H7Z B;  1YWH A;  1ERG A;  2H64 B;  1KS6 A;  2NBT A;  1UG4 A;  1TFS A;  1TXA A;  4HQP F;  5IMT D;  1NOR A;  2JQP A;  4DO8 A;  1CDS A;  1CVO A;  3NEQ A;  3VTS A;  2MFA A;  5DZ5 A;  1CXO A;  1MR6 A;  1FAS A;  1CDR A;  1QKE A;  2BTX A;  2MHY A;  4BDT B;  2J8B A;  3U73 U;  4RUD A;  2ABX A;  1KFH A;  2L03 A;  1NXB A;  2MUP A;  2FD6 U;  1KXI A;  2L5S A;  2UX2 A;  1HAJ A;  4AEA A;  2H62 D;  1W6B A;  1LXH A;  2I9B E;  1IDH A;  2CDX A;  1LX5 B;  2QJ9 C;  1JE9 A;  3ERA A;  1IQ9 A;  2H7Z A;  2LCR A;  3U74 U;  1KL8 A;  4P7U A;  1KBA A;  1FRA A;  3LAQ U;  2GOO B;  1REW C;  2OFS A;  1QKD A;  1B41 B;  3QB4 B;  4OM5 A;  1BXP A;  2MJ0 A;  2H5F A;  1CTX A;  1FSS B;  2MJ4 A;  2PJY C;  1RL5 A;  4XJJ A;  2QJB C;  4IYE A;  1ERA A;  4EY8 B;  1RGJ A;  2H62 C;  4BIK B;  2CRT A;  3NH7 A;  1HC9 A;  2HLQ A;  3KFD I;  1COE A;  1S4Y A;  1KTZ B;  1QM7 A;  1JGK A;  2CTX A;  1F94 A;  3FEV A;  1CDQ A;  2X8B B;  2MUO A;  1F8U B;  4ZQY A;  1CXN A;  2H8U A;  3KFD E;  1KBS A;  1NEA A;  4LFT A;  1PLO A;  1TXB A;  2N99 A;  3EBX A;  1JBD A;  1KC4 A;  1DRS A;  4OM4 A;  4FAO E;  3HH7 A;  2HLR A;  3NDS A;  1BTE A;  1NYS A;  2ERA A;  1HOY A;  2PJY B;  1CDT A;  1V6P A;  1VB0 A;  2QC1 A;  1IDL A;  2CRS A;  1IJC A;  1MAH F;  1IK8 A;  4UY2 C;  1CHV S;  1FFJ A;  1M9Z A;  1FF4 A;  1LJZ A;  2H64 C; 
#chains in the Genus database with same CATH topology
 3BT1 U;  4QTI U;  4FAO C;  2VLW A;  1IDG A;  2BHI A;  6EBX A;  2GOO C;  1TGX A;  1LXG A;  1ES7 B;  2UWR A;  2LA1 A;  1CRE A;  2MJY A;  2QJA C;  3PLC A;  1I02 A;  1NYU A;  1KBT A;  1FSC A;  1KU6 B;  5DU1 A;  1HC9 B;  2JVE A;  2K3G A;  1ZAD A;  1NTX A;  1CB9 A;  3BT2 U;  4KSN A;  1XT3 A;  1ABT A;  1CCQ A;  5DO6 A;  1G6M A;  1IDI A;  1HAA A;  5EBX A;  3EVS C;  1ONJ A;  1IKC A;  5IMY C;  1L4W A;  1CRF A;  1H0J A;  1COD A;  1LSI A;  1NTN A;  2CCX A;  2H7Z B;  1YWH A;  1ERG A;  2H64 B;  1KS6 A;  2NBT A;  1UG4 A;  1TFS A;  1TXA A;  4HQP F;  5IMT D;  1NOR A;  2JQP A;  4DO8 A;  1CDS A;  1CVO A;  3NEQ A;  3VTS A;  2MFA A;  5DZ5 A;  1CXO A;  1MR6 A;  1FAS A;  1CDR A;  1QKE A;  2BTX A;  2MHY A;  4BDT B;  2J8B A;  3U73 U;  4RUD A;  2ABX A;  1KFH A;  2L03 A;  1NXB A;  2MUP A;  2FD6 U;  1KXI A;  2L5S A;  2UX2 A;  1HAJ A;  4AEA A;  2H62 D;  1W6B A;  1LXH A;  2I9B E;  1IDH A;  2CDX A;  1LX5 B;  2QJ9 C;  1JE9 A;  3ERA A;  1IQ9 A;  2H7Z A;  2LCR A;  3U74 U;  1KL8 A;  4P7U A;  1KBA A;  1FRA A;  3LAQ U;  2GOO B;  1REW C;  2OFS A;  1QKD A;  1B41 B;  3QB4 B;  4OM5 A;  1BXP A;  2MJ0 A;  2H5F A;  1CTX A;  1FSS B;  2MJ4 A;  2PJY C;  1RL5 A;  4XJJ A;  2QJB C;  4IYE A;  1ERA A;  4EY8 B;  1RGJ A;  2H62 C;  4BIK B;  2CRT A;  3NH7 A;  1HC9 A;  2HLQ A;  3KFD I;  1COE A;  1S4Y A;  1KTZ B;  1QM7 A;  1JGK A;  2CTX A;  1F94 A;  3FEV A;  1CDQ A;  2X8B B;  2MUO A;  1F8U B;  4ZQY A;  1CXN A;  2H8U A;  3KFD E;  1KBS A;  1NEA A;  4LFT A;  1PLO A;  1TXB A;  2N99 A;  3EBX A;  1JBD A;  1KC4 A;  1DRS A;  4OM4 A;  4FAO E;  3HH7 A;  2HLR A;  3NDS A;  1BTE A;  1NYS A;  2ERA A;  1HOY A;  2PJY B;  1CDT A;  1V6P A;  1VB0 A;  2QC1 A;  1IDL A;  2CRS A;  1IJC A;  1MAH F;  1IK8 A;  4UY2 C;  1CHV S;  1FFJ A;  1M9Z A;  1FF4 A;  1LJZ A;  2H64 C; 
#chains in the Genus database with same CATH homology
 3BT1 U;  4QTI U;  4FAO C;  2VLW A;  1IDG A;  2BHI A;  6EBX A;  2GOO C;  1TGX A;  1LXG A;  1ES7 B;  2UWR A;  2LA1 A;  1CRE A;  2MJY A;  2QJA C;  3PLC A;  1I02 A;  1NYU A;  1KBT A;  1FSC A;  1KU6 B;  5DU1 A;  1HC9 B;  2JVE A;  2K3G A;  1ZAD A;  1NTX A;  1CB9 A;  3BT2 U;  4KSN A;  1XT3 A;  1ABT A;  1CCQ A;  5DO6 A;  1G6M A;  1IDI A;  1HAA A;  5EBX A;  3EVS C;  1ONJ A;  1IKC A;  5IMY C;  1L4W A;  1CRF A;  1H0J A;  1COD A;  1LSI A;  1NTN A;  2CCX A;  2H7Z B;  1YWH A;  1ERG A;  2H64 B;  1KS6 A;  2NBT A;  1UG4 A;  1TFS A;  1TXA A;  4HQP F;  5IMT D;  1NOR A;  2JQP A;  4DO8 A;  1CDS A;  1CVO A;  3NEQ A;  3VTS A;  2MFA A;  5DZ5 A;  1CXO A;  1MR6 A;  1FAS A;  1CDR A;  1QKE A;  2BTX A;  2MHY A;  4BDT B;  2J8B A;  3U73 U;  4RUD A;  2ABX A;  1KFH A;  2L03 A;  1NXB A;  2MUP A;  2FD6 U;  1KXI A;  2L5S A;  2UX2 A;  1HAJ A;  4AEA A;  2H62 D;  1W6B A;  1LXH A;  2I9B E;  1IDH A;  2CDX A;  1LX5 B;  2QJ9 C;  1JE9 A;  3ERA A;  1IQ9 A;  2H7Z A;  2LCR A;  3U74 U;  1KL8 A;  4P7U A;  1KBA A;  1FRA A;  3LAQ U;  2GOO B;  1REW C;  2OFS A;  1QKD A;  1B41 B;  3QB4 B;  4OM5 A;  1BXP A;  2MJ0 A;  2H5F A;  1CTX A;  1FSS B;  2MJ4 A;  2PJY C;  1RL5 A;  4XJJ A;  2QJB C;  4IYE A;  1ERA A;  4EY8 B;  1RGJ A;  2H62 C;  4BIK B;  2CRT A;  3NH7 A;  1HC9 A;  2HLQ A;  3KFD I;  1COE A;  1S4Y A;  1KTZ B;  1QM7 A;  1JGK A;  2CTX A;  1F94 A;  3FEV A;  1CDQ A;  2X8B B;  2MUO A;  1F8U B;  4ZQY A;  1CXN A;  2H8U A;  3KFD E;  1KBS A;  1NEA A;  4LFT A;  1PLO A;  1TXB A;  2N99 A;  3EBX A;  1JBD A;  1KC4 A;  1DRS A;  4OM4 A;  4FAO E;  3HH7 A;  2HLR A;  3NDS A;  1BTE A;  1NYS A;  2ERA A;  1HOY A;  2PJY B;  1CDT A;  1V6P A;  1VB0 A;  2QC1 A;  1IDL A;  2CRS A;  1IJC A;  1MAH F;  1IK8 A;  4UY2 C;  1CHV S;  1FFJ A;  1M9Z A;  1FF4 A;  1LJZ A;  2H64 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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