5DO6A

Crystal structure of dendroaspis polylepis venom mambalgin-1 t23a mutant
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
57
structure length
57
Chain Sequence
LKCYQHGKVVTCHRDMKFCYHNAGMPFRNLKLILQGCSSSCSETENNKCCSTDRCNK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mambalgin-1 Pain-relieving Peptide, Stepwise Solid-phase Synthesis, Crystal Structure, and Functional Domain for Acid-sensing Ion Channel 1a Inhibition.
pubmed doi rcsb
molecule tags Toxin
molecule keywords Mambalgin-1
total genus 13
structure length 57
sequence length 57
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-09-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 5do6A00
1CXNA 1NEAA 1F8UB 2ABXA 2K3GA 4LFTA 5EBXA 1CVOA 1RGJA 1I02A 2L5SA 2PJYC 1FRAA 3KFDE 1KU6B 2CRTA 1L4WA 3U74U 1QKEA 2LCRA 1JBDA 2PJYB 1IQ9A 1UG4A 3PLCA 2H62D 3NH7A 1G6MA 4IYEA 1IJCA 1BXPA 3U73U 1CDQA 2H7ZA 2UX2A 3ERAA 2MHYA 3EVSC 2MJ0A 1FFJA 1CODA 1CRFA 1VB0A 4UY2C 1ES7B 1MAHF 1LXGA 1LSIA 1XT3A 2N99A 2QC1A 2J8BA 1IK8A 1CB9A 1ERGA 1CCQA 1M9ZA 1KBAA 3VTSA 1KBSA 1H0JA 1HC9B 3NEQA 2X8BB 5IMYC 1COEA 2CRSA 1HOYA 1KFHA 1PLOA 1REWC 4QTIU 1CDTA 2HLQA 2VLWA 4OM4A 1ABTA 1DRSA 1KC4A 2ERAA 1ONJA 1TXBA 2H5FA 3BT1U 5DU1A 4FAOE 1TXAA 2MJ4A 3FEVA 1JGKA 4AEAA 2H62C 1CTXA 4EY8B 1CREA 2MJYA 2QJAC 4XJJA 2LA1A 2H64C 1KS6A 2MFAA 1IDHA 4DO8A 2H64B 4P7UA 1NYSA 1RL5A 1NYUA 3HH7A 1QM7A 1TGXA 1IDGA 3BT2U 2HLRA 1F94A 1LJZA 1V6PA 2FD6U 1CDSA 2BTXA 2L03A 3NDSA 1FF4A 1KL8A 1FSSB 2CTXA 1ZADA 5IMTD 1YWHA 4FAOC 1HAAA 1NXBA 6EBXA 2I9BE 1TFSA 1W6BA 2CCXA 2NBTA 2UWRA 2CDXA 4ZQYA 1IKCA 2H7ZB 3QB4B 5DO6A 3LAQU 1NTNA 4OM5A 1HC9A 1MR6A 1BTEA 4RUDA 1NORA 2JQPA 1CHVS 1IDLA 2OFSA 4HQPF 1FSCA 2GOOC 1HAJA 1KBTA 3KFDI 2MUPA 2BHIA 3EBXA 1ERAA 1KXIA 2GOOB 2MUOA 4BIKB 1CDRA 1QKDA 1IDIA 1JE9A 1CXOA 1FASA 1KTZB 1LX5B 5DZ5A 1S4YA 2QJ9C 2H8UA 2JVEA 1B41B 1LXHA 2QJBC 4BDTB 1NTXA
chains in the Genus database with same CATH superfamily
1CXNA 1NEAA 1F8UB 2ABXA 2K3GA 4LFTA 5EBXA 1CVOA 1RGJA 1I02A 2L5SA 2PJYC 1FRAA 3KFDE 1KU6B 2CRTA 1L4WA 3U74U 1QKEA 2LCRA 1JBDA 2PJYB 1IQ9A 1UG4A 3PLCA 2H62D 3NH7A 1G6MA 4IYEA 1IJCA 1BXPA 3U73U 1CDQA 2H7ZA 2UX2A 3ERAA 2MHYA 3EVSC 2MJ0A 1FFJA 1CODA 1CRFA 1VB0A 4UY2C 1ES7B 1MAHF 1LXGA 1LSIA 1XT3A 2N99A 2QC1A 2J8BA 1IK8A 1CB9A 1ERGA 1CCQA 1M9ZA 1KBAA 3VTSA 1KBSA 1H0JA 1HC9B 3NEQA 2X8BB 5IMYC 1COEA 2CRSA 1HOYA 1KFHA 1PLOA 1REWC 4QTIU 1CDTA 2HLQA 2VLWA 4OM4A 1ABTA 1DRSA 1KC4A 2ERAA 1ONJA 1TXBA 2H5FA 3BT1U 4KSNA 5DU1A 4FAOE 1TXAA 2MJ4A 3FEVA 1JGKA 4AEAA 2H62C 1CTXA 4EY8B 1CREA 2MJYA 2QJAC 4XJJA 2LA1A 2H64C 1KS6A 2MFAA 1IDHA 4DO8A 2H64B 4P7UA 1NYSA 1RL5A 1NYUA 3HH7A 1QM7A 1TGXA 1IDGA 3BT2U 2HLRA 1F94A 1LJZA 1V6PA 2FD6U 1CDSA 2BTXA 2L03A 3NDSA 1FF4A 1KL8A 1FSSB 2CTXA 1ZADA 5IMTD 1YWHA 4FAOC 1HAAA 1NXBA 6EBXA 2I9BE 1TFSA 1W6BA 2CCXA 2NBTA 2UWRA 2CDXA 4ZQYA 1IKCA 2H7ZB 3QB4B 5DO6A 3LAQU 1NTNA 4OM5A 1HC9A 1MR6A 1BTEA 4RUDA 1NORA 2JQPA 1CHVS 1IDLA 2OFSA 4HQPF 1FSCA 2GOOC 1HAJA 1KBTA 3KFDI 2MUPA 2BHIA 3EBXA 1ERAA 1KXIA 2GOOB 2MUOA 4BIKB 1CDRA 1QKDA 1IDIA 1JE9A 1CXOA 1FASA 1KTZB 1LX5B 5DZ5A 1S4YA 2QJ9C 2H8UA 2JVEA 1B41B 1LXHA 2QJBC 4BDTB 1NTXA
chains in the Genus database with same CATH topology
1CXNA 1NEAA 1F8UB 2ABXA 2K3GA 4LFTA 5EBXA 1CVOA 1RGJA 1I02A 2L5SA 2PJYC 1FRAA 3KFDE 1KU6B 2CRTA 1L4WA 3U74U 1QKEA 2LCRA 1JBDA 2PJYB 1IQ9A 1UG4A 3PLCA 2H62D 3NH7A 1G6MA 4IYEA 1IJCA 1BXPA 3U73U 1CDQA 2H7ZA 2UX2A 3ERAA 2MHYA 3EVSC 2MJ0A 1FFJA 1CODA 1CRFA 1VB0A 4UY2C 1ES7B 1MAHF 1LXGA 1LSIA 1XT3A 2N99A 2QC1A 2J8BA 1IK8A 1CB9A 1ERGA 1CCQA 1M9ZA 1KBAA 3VTSA 1KBSA 1H0JA 1HC9B 3NEQA 2X8BB 5IMYC 1COEA 2CRSA 1HOYA 1KFHA 1PLOA 1REWC 4QTIU 1CDTA 2HLQA 2VLWA 4OM4A 1ABTA 1DRSA 1KC4A 2ERAA 1ONJA 1TXBA 2H5FA 3BT1U 4KSNA 5DU1A 4FAOE 1TXAA 2MJ4A 3FEVA 1JGKA 4AEAA 2H62C 1CTXA 4EY8B 1CREA 2MJYA 2QJAC 4XJJA 2LA1A 2H64C 1KS6A 2MFAA 1IDHA 4DO8A 2H64B 4P7UA 1NYSA 1RL5A 1NYUA 3HH7A 1QM7A 1TGXA 1IDGA 3BT2U 2HLRA 1F94A 1LJZA 1V6PA 2FD6U 1CDSA 2BTXA 2L03A 3NDSA 1FF4A 1KL8A 1FSSB 2CTXA 1ZADA 5IMTD 1YWHA 4FAOC 1HAAA 1NXBA 6EBXA 2I9BE 1TFSA 1W6BA 2CCXA 2NBTA 2UWRA 2CDXA 4ZQYA 1IKCA 2H7ZB 3QB4B 5DO6A 3LAQU 1NTNA 4OM5A 1HC9A 1MR6A 1BTEA 4RUDA 1NORA 2JQPA 1CHVS 1IDLA 2OFSA 4HQPF 1FSCA 2GOOC 1HAJA 1KBTA 3KFDI 2MUPA 2BHIA 3EBXA 1ERAA 1KXIA 2GOOB 2MUOA 4BIKB 1CDRA 1QKDA 1IDIA 1JE9A 1CXOA 1FASA 1KTZB 1LX5B 5DZ5A 1S4YA 2QJ9C 2H8UA 2JVEA 1B41B 1LXHA 2QJBC 4BDTB 1NTXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1CXN A;  1NEA A;  1F8U B;  2ABX A;  2K3G A;  4LFT A;  5EBX A;  1CVO A;  1RGJ A;  1I02 A;  2L5S A;  2PJY C;  1FRA A;  3KFD E;  1KU6 B;  2CRT A;  1L4W A;  3U74 U;  1QKE A;  2LCR A;  1JBD A;  2PJY B;  1IQ9 A;  1UG4 A;  3PLC A;  2H62 D;  3NH7 A;  1G6M A;  4IYE A;  1IJC A;  1BXP A;  3U73 U;  1CDQ A;  2H7Z A;  2UX2 A;  3ERA A;  2MHY A;  3EVS C;  2MJ0 A;  1FFJ A;  1COD A;  1CRF A;  1VB0 A;  4UY2 C;  1ES7 B;  1MAH F;  1LXG A;  1LSI A;  1XT3 A;  2N99 A;  2QC1 A;  2J8B A;  1IK8 A;  1CB9 A;  1ERG A;  1CCQ A;  1M9Z A;  1KBA A;  3VTS A;  1KBS A;  1H0J A;  1HC9 B;  3NEQ A;  2X8B B;  5IMY C;  1COE A;  2CRS A;  1HOY A;  1KFH A;  1PLO A;  1REW C;  4QTI U;  1CDT A;  2HLQ A;  2VLW A;  4OM4 A;  1ABT A;  1DRS A;  1KC4 A;  2ERA A;  1ONJ A;  1TXB A;  2H5F A;  3BT1 U;  5DU1 A;  4FAO E;  1TXA A;  2MJ4 A;  3FEV A;  1JGK A;  4AEA A;  2H62 C;  1CTX A;  4EY8 B;  1CRE A;  2MJY A;  2QJA C;  4XJJ A;  2LA1 A;  2H64 C;  1KS6 A;  2MFA A;  1IDH A;  4DO8 A;  2H64 B;  4P7U A;  1NYS A;  1RL5 A;  1NYU A;  3HH7 A;  1QM7 A;  1TGX A;  1IDG A;  3BT2 U;  2HLR A;  1F94 A;  1LJZ A;  1V6P A;  2FD6 U;  1CDS A;  2BTX A;  2L03 A;  3NDS A;  1FF4 A;  1KL8 A;  1FSS B;  2CTX A;  1ZAD A;  5IMT D;  1YWH A;  4FAO C;  1HAA A;  1NXB A;  6EBX A;  2I9B E;  1TFS A;  1W6B A;  2CCX A;  2NBT A;  2UWR A;  2CDX A;  4ZQY A;  1IKC A;  2H7Z B;  3QB4 B;  5DO6 A;  3LAQ U;  1NTN A;  4OM5 A;  1HC9 A;  1MR6 A;  1BTE A;  4RUD A;  1NOR A;  2JQP A;  1CHV S;  1IDL A;  2OFS A;  4HQP F;  1FSC A;  2GOO C;  1HAJ A;  1KBT A;  3KFD I;  2MUP A;  2BHI A;  3EBX A;  1ERA A;  1KXI A;  2GOO B;  2MUO A;  4BIK B;  1CDR A;  1QKD A;  1IDI A;  1JE9 A;  1CXO A;  1FAS A;  1KTZ B;  1LX5 B;  5DZ5 A;  1S4Y A;  2QJ9 C;  2H8U A;  2JVE A;  1B41 B;  1LXH A;  2QJB C;  4BDT B;  1NTX A; 
#chains in the Genus database with same CATH topology
 1CXN A;  1NEA A;  1F8U B;  2ABX A;  2K3G A;  4LFT A;  5EBX A;  1CVO A;  1RGJ A;  1I02 A;  2L5S A;  2PJY C;  1FRA A;  3KFD E;  1KU6 B;  2CRT A;  1L4W A;  3U74 U;  1QKE A;  2LCR A;  1JBD A;  2PJY B;  1IQ9 A;  1UG4 A;  3PLC A;  2H62 D;  3NH7 A;  1G6M A;  4IYE A;  1IJC A;  1BXP A;  3U73 U;  1CDQ A;  2H7Z A;  2UX2 A;  3ERA A;  2MHY A;  3EVS C;  2MJ0 A;  1FFJ A;  1COD A;  1CRF A;  1VB0 A;  4UY2 C;  1ES7 B;  1MAH F;  1LXG A;  1LSI A;  1XT3 A;  2N99 A;  2QC1 A;  2J8B A;  1IK8 A;  1CB9 A;  1ERG A;  1CCQ A;  1M9Z A;  1KBA A;  3VTS A;  1KBS A;  1H0J A;  1HC9 B;  3NEQ A;  2X8B B;  5IMY C;  1COE A;  2CRS A;  1HOY A;  1KFH A;  1PLO A;  1REW C;  4QTI U;  1CDT A;  2HLQ A;  2VLW A;  4OM4 A;  1ABT A;  1DRS A;  1KC4 A;  2ERA A;  1ONJ A;  1TXB A;  2H5F A;  3BT1 U;  4KSN A;  5DU1 A;  4FAO E;  1TXA A;  2MJ4 A;  3FEV A;  1JGK A;  4AEA A;  2H62 C;  1CTX A;  4EY8 B;  1CRE A;  2MJY A;  2QJA C;  4XJJ A;  2LA1 A;  2H64 C;  1KS6 A;  2MFA A;  1IDH A;  4DO8 A;  2H64 B;  4P7U A;  1NYS A;  1RL5 A;  1NYU A;  3HH7 A;  1QM7 A;  1TGX A;  1IDG A;  3BT2 U;  2HLR A;  1F94 A;  1LJZ A;  1V6P A;  2FD6 U;  1CDS A;  2BTX A;  2L03 A;  3NDS A;  1FF4 A;  1KL8 A;  1FSS B;  2CTX A;  1ZAD A;  5IMT D;  1YWH A;  4FAO C;  1HAA A;  1NXB A;  6EBX A;  2I9B E;  1TFS A;  1W6B A;  2CCX A;  2NBT A;  2UWR A;  2CDX A;  4ZQY A;  1IKC A;  2H7Z B;  3QB4 B;  5DO6 A;  3LAQ U;  1NTN A;  4OM5 A;  1HC9 A;  1MR6 A;  1BTE A;  4RUD A;  1NOR A;  2JQP A;  1CHV S;  1IDL A;  2OFS A;  4HQP F;  1FSC A;  2GOO C;  1HAJ A;  1KBT A;  3KFD I;  2MUP A;  2BHI A;  3EBX A;  1ERA A;  1KXI A;  2GOO B;  2MUO A;  4BIK B;  1CDR A;  1QKD A;  1IDI A;  1JE9 A;  1CXO A;  1FAS A;  1KTZ B;  1LX5 B;  5DZ5 A;  1S4Y A;  2QJ9 C;  2H8U A;  2JVE A;  1B41 B;  1LXH A;  2QJB C;  4BDT B;  1NTX A; 
#chains in the Genus database with same CATH homology
 1CXN A;  1NEA A;  1F8U B;  2ABX A;  2K3G A;  4LFT A;  5EBX A;  1CVO A;  1RGJ A;  1I02 A;  2L5S A;  2PJY C;  1FRA A;  3KFD E;  1KU6 B;  2CRT A;  1L4W A;  3U74 U;  1QKE A;  2LCR A;  1JBD A;  2PJY B;  1IQ9 A;  1UG4 A;  3PLC A;  2H62 D;  3NH7 A;  1G6M A;  4IYE A;  1IJC A;  1BXP A;  3U73 U;  1CDQ A;  2H7Z A;  2UX2 A;  3ERA A;  2MHY A;  3EVS C;  2MJ0 A;  1FFJ A;  1COD A;  1CRF A;  1VB0 A;  4UY2 C;  1ES7 B;  1MAH F;  1LXG A;  1LSI A;  1XT3 A;  2N99 A;  2QC1 A;  2J8B A;  1IK8 A;  1CB9 A;  1ERG A;  1CCQ A;  1M9Z A;  1KBA A;  3VTS A;  1KBS A;  1H0J A;  1HC9 B;  3NEQ A;  2X8B B;  5IMY C;  1COE A;  2CRS A;  1HOY A;  1KFH A;  1PLO A;  1REW C;  4QTI U;  1CDT A;  2HLQ A;  2VLW A;  4OM4 A;  1ABT A;  1DRS A;  1KC4 A;  2ERA A;  1ONJ A;  1TXB A;  2H5F A;  3BT1 U;  4KSN A;  5DU1 A;  4FAO E;  1TXA A;  2MJ4 A;  3FEV A;  1JGK A;  4AEA A;  2H62 C;  1CTX A;  4EY8 B;  1CRE A;  2MJY A;  2QJA C;  4XJJ A;  2LA1 A;  2H64 C;  1KS6 A;  2MFA A;  1IDH A;  4DO8 A;  2H64 B;  4P7U A;  1NYS A;  1RL5 A;  1NYU A;  3HH7 A;  1QM7 A;  1TGX A;  1IDG A;  3BT2 U;  2HLR A;  1F94 A;  1LJZ A;  1V6P A;  2FD6 U;  1CDS A;  2BTX A;  2L03 A;  3NDS A;  1FF4 A;  1KL8 A;  1FSS B;  2CTX A;  1ZAD A;  5IMT D;  1YWH A;  4FAO C;  1HAA A;  1NXB A;  6EBX A;  2I9B E;  1TFS A;  1W6B A;  2CCX A;  2NBT A;  2UWR A;  2CDX A;  4ZQY A;  1IKC A;  2H7Z B;  3QB4 B;  5DO6 A;  3LAQ U;  1NTN A;  4OM5 A;  1HC9 A;  1MR6 A;  1BTE A;  4RUD A;  1NOR A;  2JQP A;  1CHV S;  1IDL A;  2OFS A;  4HQP F;  1FSC A;  2GOO C;  1HAJ A;  1KBT A;  3KFD I;  2MUP A;  2BHI A;  3EBX A;  1ERA A;  1KXI A;  2GOO B;  2MUO A;  4BIK B;  1CDR A;  1QKD A;  1IDI A;  1JE9 A;  1CXO A;  1FAS A;  1KTZ B;  1LX5 B;  5DZ5 A;  1S4Y A;  2QJ9 C;  2H8U A;  2JVE A;  1B41 B;  1LXH A;  2QJB C;  4BDT B;  1NTX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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