2EZBA

Amino terminal domain of enzyme i from escherichia coli, nmr, 14 structures
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
249
structure length
249
Chain Sequence
MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRAVQEQVASE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Defining long range order in NMR structure determination from the dependence of heteronuclear relaxation times on rotational diffusion anisotropy.
pubmed doi rcsb
molecule tags Phosphotransferase
source organism Escherichia coli
molecule keywords PHOSPHOTRANSFERASE SYSTEM, ENZYME I
total genus 75
structure length 249
sequence length 249
ec nomenclature ec 2.7.3.9: Phosphoenolpyruvate--protein phosphotransferase.
pdb deposition date 1997-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00391 PEP-utilizers PEP-utilising enzyme, mobile domain
A PF05524 PEP-utilisers_N PEP-utilising enzyme, N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.10 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 PtsI, HPr-binding domain 2ezbA02
3.50.30.10 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Phosphohistidine domain 2ezbA01
3EZEA 1ZYMA 3T0TA 3T07A 1JDEA 1VBGA 2E28A 1GGOA 2R82A 2DIKA 3EZAA 3T05A 3EZBA 1VBHA 5JVLA 2EZAA 1EZAA 2EZBA 2HROA 2OLSA 2HI6A 1DIKA 2FM4A 1KC7A 2HWGA 1EZBA 2MP0A 1KBLA 2EZCA 2X0SA
chains in the Genus database with same CATH superfamily
4C5UA 1ZYMA 2C6CA 1YNND 2K3QA 3BI1A 2X0PA 3TYXA 4P4FA 4OC5A 1I3QA 2R92A 2X0OA 2LPJA 2K3OA 4JYWA 3LR8A 3D7GA 2NVXA 1KBLA 3GTJA 5F1YA 2R93A 1R9TA 1JDBC 3TLGA 1GGOA 1Y2MA 3LR2A 2DIKA 1EZAA 2A6HD 3TLGB 2HWGA 1TWHA 2YJVA 1WVMA 2OR4A 2VUMA 1T6PA 4C85A 4C5RA 5FD8A 2XEJA 4C9EA 1V6CA 3G23A 2R82A 4P4DA 2CIJA 5JVLA 2EZBA 4J0NA 2JA5A 4CEJA 2MX9A 2E2HA 2MP0A 3EIFA 3EZEA 2XEIA 2Y0NA 4MCPA 4C8UA 2AQLA 1TWAA 4C9UA 4CDKA 3I6SA 4NGNA 1Y9ZA 4C5SA 3SJFA 4OC4A 3H0GA 2EK8A 4P4EA 1TWCA 1XF1A 4IIYA 4P4BA 1CX8A 4C8FA 1TWGA 2JBJA 5JYBA 4MCQA 3D7DA 4EYSA 3K4IA 1C3OB 2JBKA 1HQMD 3GTOA 1ZL0A 2YIIA 3GTGA 3GTKA 3NOJA 1KEEB 2GP4A 2EZCA 3SR3A 4OC2A 2EK9A 1VI4A 2LPIA 4CQ5A 4COGA 1DIKA 4MCSA 1CS0B 4YN3A 1JDEA 3SJXA 2D0OA 3D7FA 4MJXA 4C8TA 1VBHA 3S9MA 4V2RA 4CDJA 5F09A 2A6ED 4NGQA 3KRVA 4P4JA 4BABA 1CE8B 4BAAA 2C5QA 4NGMA 1ZRSA 3T07A 1IW7D 3NZ4A 3GTQA 3EZAA 3GTMA 2CW0D 2XEGA 5D29A 3TLEA 2JA6A 2YJTA 1Y1WA 2X0SA 2R7ZA 4FBSA 1SMYD 2LTHA 2C6GA 4NGSA 3T05A 4P45A 4TWEA 4C2MA 1J3LA 2OLSA 4CEHA 4JZ0A 5IB9A 4OC0A 4C84A 1KC7A 2NVYA 1EZBA 3GTLA 4NGTA 1SFOA 2LYIA 2A68D 1VBGA 2PCNA 2MQAA 2YU9A 3VTAA 2HROA 4MI1A 4V2QA 1I50A 4W9YA 3GTPA 1T6JA 1WCMA 2F5JA 3S9NA 4LQGA 2C6PA 2N1DB 4E94A 4IIXA 3LRDA 3FEEA 4C9RA 4C8AA 4NGPA 4H1HA 3CQZA 2OOTA 1K83A 4CEIA 2VK9A 2XEFA 1R61A 4INJA 1A9XB 3SJGA 3TLCA 3U1BA 4C99A 3KASA 2EZAA 1TWFA 2PVWA 1ZYRD 1T36B 2HI6A 3IWWA 3K9TA 3BI0A 1Y1VA 2B63A 2FIOA 3SJEA 4C86A 4JVOA 2AUNA 2BE5D 2PVVA 4C8CA 2FIPA 3TLZA 4P4IA 3TLAA 1NBWA 2FM4A 2E2IA 3ICUA 3U44A 1W27A 2JA7A 1YNJD 2E28A 3IIBA 3BHXA 3C8OA 5F9MA 3FF3A 2O5JD 1BXRB 1C30B 4C9AA 4TJVA 3TLYA 3RBUA 4C8PA 3D7HA 4P44A 3U4QA 4TJXA 4MCRA 4CO9A 4COBA 2D0PA 2LKMB 5IR2A 4E5SA 3T0TA 1Z8LA 4M8DA 4NGRA 4OC1A 3LR6A 1I6VD 1Q5XA 4C9VA 4C6GA 1NXJA 5IZ2A 5F5XA 2K3NA 3S9LA 2A69D 3FEDA 2MX8A 5ELYA 2AUMA 4KNGE 3GJZA 1DE4C 4X3RA 3BXMA 4OMEA 3EZBA 1M6VB 5K99A 3T5MA 2N3EA 4CZ1A 4OC3A 3TLBA 4QIWA 3I74A 3FECA 2X0QA 3FKIA 2B0AA
chains in the Genus database with same CATH topology
3EZEA 1ZYMA 3T0TA 3T07A 1JDEA 1VBGA 2E28A 1GGOA 2R82A 2DIKA 3EZAA 3T05A 3EZBA 1VBHA 5JVLA 2EZAA 1EZAA 2EZBA 2HROA 2OLSA 2HI6A 1DIKA 2FM4A 1KC7A 2HWGA 1EZBA 2MP0A 1KBLA 2EZCA 2X0SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EZE A;  1ZYM A;  3T0T A;  3T07 A;  1JDE A;  1VBG A;  2E28 A;  1GGO A;  2R82 A;  2DIK A;  3EZA A;  3T05 A;  3EZB A;  1VBH A;  5JVL A;  2EZA A;  1EZA A;  2EZB A;  2HRO A;  2OLS A;  2HI6 A;  1DIK A;  2FM4 A;  1KC7 A;  2HWG A;  1EZB A;  2MP0 A;  1KBL A;  2EZC A;  2X0S A; 
#chains in the Genus database with same CATH topology
 4C5U A;  1ZYM A;  2C6C A;  1YNN D;  2K3Q A;  3BI1 A;  2X0P A;  3TYX A;  4P4F A;  4OC5 A;  1I3Q A;  2R92 A;  2X0O A;  2LPJ A;  2K3O A;  4JYW A;  3LR8 A;  3D7G A;  2NVX A;  1KBL A;  3GTJ A;  5F1Y A;  2R93 A;  1R9T A;  1JDB C;  3TLG A;  1GGO A;  1Y2M A;  3LR2 A;  2DIK A;  1EZA A;  2A6H D;  3TLG B;  2HWG A;  1TWH A;  2YJV A;  1WVM A;  2OR4 A;  2VUM A;  1T6P A;  4C85 A;  4C5R A;  5FD8 A;  2XEJ A;  4C9E A;  1V6C A;  3G23 A;  2R82 A;  4P4D A;  2CIJ A;  5JVL A;  2EZB A;  4J0N A;  2JA5 A;  4CEJ A;  2MX9 A;  2E2H A;  2MP0 A;  3EIF A;  3EZE A;  2XEI A;  2Y0N A;  4MCP A;  4C8U A;  2AQL A;  1TWA A;  4C9U A;  4CDK A;  3I6S A;  4NGN A;  1Y9Z A;  4C5S A;  3SJF A;  4OC4 A;  3H0G A;  2EK8 A;  4P4E A;  1TWC A;  1XF1 A;  4IIY A;  4P4B A;  1CX8 A;  4C8F A;  1TWG A;  2JBJ A;  5JYB A;  4MCQ A;  3D7D A;  4EYS A;  3K4I A;  1C3O B;  2JBK A;  1HQM D;  3GTO A;  1ZL0 A;  2YII A;  3GTG A;  3GTK A;  3NOJ A;  1KEE B;  2GP4 A;  2EZC A;  3SR3 A;  4OC2 A;  2EK9 A;  1VI4 A;  2LPI A;  4CQ5 A;  4COG A;  1DIK A;  4MCS A;  1CS0 B;  4YN3 A;  1JDE A;  3SJX A;  2D0O A;  3D7F A;  4MJX A;  4C8T A;  1VBH A;  3S9M A;  4V2R A;  4CDJ A;  5F09 A;  2A6E D;  4NGQ A;  3KRV A;  4P4J A;  4BAB A;  1CE8 B;  4BAA A;  2C5Q A;  4NGM A;  1ZRS A;  3T07 A;  1IW7 D;  3NZ4 A;  3GTQ A;  3EZA A;  3GTM A;  2CW0 D;  2XEG A;  5D29 A;  3TLE A;  2JA6 A;  2YJT A;  1Y1W A;  2X0S A;  2R7Z A;  4FBS A;  1SMY D;  2LTH A;  2C6G A;  4NGS A;  3T05 A;  4P45 A;  4TWE A;  4C2M A;  1J3L A;  2OLS A;  4CEH A;  4JZ0 A;  5IB9 A;  4OC0 A;  4C84 A;  1KC7 A;  2NVY A;  1EZB A;  3GTL A;  4NGT A;  1SFO A;  2LYI A;  2A68 D;  1VBG A;  2PCN A;  2MQA A;  2YU9 A;  3VTA A;  2HRO A;  4MI1 A;  4V2Q A;  1I50 A;  4W9Y A;  3GTP A;  1T6J A;  1WCM A;  2F5J A;  3S9N A;  4LQG A;  2C6P A;  2N1D B;  4E94 A;  4IIX A;  3LRD A;  3FEE A;  4C9R A;  4C8A A;  4NGP A;  4H1H A;  3CQZ A;  2OOT A;  1K83 A;  4CEI A;  2VK9 A;  2XEF A;  1R61 A;  4INJ A;  1A9X B;  3SJG A;  3TLC A;  3U1B A;  4C99 A;  3KAS A;  2EZA A;  1TWF A;  2PVW A;  1ZYR D;  1T36 B;  2HI6 A;  3IWW A;  3K9T A;  3BI0 A;  1Y1V A;  2B63 A;  2FIO A;  3SJE A;  4C86 A;  4JVO A;  2AUN A;  2BE5 D;  2PVV A;  4C8C A;  2FIP A;  3TLZ A;  4P4I A;  3TLA A;  1NBW A;  2FM4 A;  2E2I A;  3ICU A;  3U44 A;  1W27 A;  2JA7 A;  1YNJ D;  2E28 A;  3IIB A;  3BHX A;  3C8O A;  5F9M A;  3FF3 A;  2O5J D;  1BXR B;  1C30 B;  4C9A A;  4TJV A;  3TLY A;  3RBU A;  4C8P A;  3D7H A;  4P44 A;  3U4Q A;  4TJX A;  4MCR A;  4CO9 A;  4COB A;  2D0P A;  2LKM B;  5IR2 A;  4E5S A;  3T0T A;  1Z8L A;  4M8D A;  4NGR A;  4OC1 A;  3LR6 A;  1I6V D;  1Q5X A;  4C9V A;  4C6G A;  1NXJ A;  5IZ2 A;  5F5X A;  2K3N A;  3S9L A;  2A69 D;  3FED A;  2MX8 A;  5ELY A;  2AUM A;  4KNG E;  3GJZ A;  1DE4 C;  4X3R A;  3BXM A;  4OME A;  3EZB A;  1M6V B;  5K99 A;  3T5M A;  2N3E A;  4CZ1 A;  4OC3 A;  3TLB A;  4QIW A;  3I74 A;  3FEC A;  2X0Q A;  3FKI A;  2B0A A; 
#chains in the Genus database with same CATH homology
 3EZE A;  1ZYM A;  3T0T A;  3T07 A;  1JDE A;  1VBG A;  2E28 A;  1GGO A;  2R82 A;  2DIK A;  3EZA A;  3T05 A;  3EZB A;  1VBH A;  5JVL A;  2EZA A;  1EZA A;  2EZB A;  2HRO A;  2OLS A;  2HI6 A;  1DIK A;  2FM4 A;  1KC7 A;  2HWG A;  1EZB A;  2MP0 A;  1KBL A;  2EZC A;  2X0S A; 
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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