1JAWA

Aminopeptidase p from e. coli low ph form
Total Genus 151
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
151
sequence length
440
structure length
440
Chain Sequence
SEISRQEFQRRRQALVEQMQPGSAALIFAAPEVTRSADSEYPYRQNSDFWYFTGFNEPEAVLVLIKSDDTHNHSVLFNRVRDLTAEIWYGRRLGQDAAPEKLGVDRALAFSEINQQLYQLLNGLDVVYHAQGEYAYADVIVNSALEKLRKGSRQNLTAPATMIDWRPVVHEMRLFKSPEEIAVLRRAGEITAMAHTRAMEKCRPGMFEYHLEGEIHHEFNRHGARYPSYNTIVGSGENGCILHYTENECEMRDGDLVLIDAGCEYKGYAGDITRTFPVNGKFTQAQREIYDIVLESLETSLRLYRPGTSILEVTGEVVRIMVSGLVKLGILKGDVDELIAQNAHRPFFMHGLSHWLGLDVHDVGVYGQDRSRILEPGMVLTVEPGLYIAPDAEVPEQYRGIGIRIEDDIVITETGNENLTASVVKKPEEIEALMVAARKQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and mechanism of a proline-specific aminopeptidase from Escherichia coli.
pubmed doi rcsb
molecule tags Proline peptidase
molecule keywords AMINOPEPTIDASE P
total genus 151
structure length 440
sequence length 440
ec nomenclature ec 3.4.11.9: Xaa-Pro aminopeptidase.
pdb deposition date 1997-12-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF05195 AMP_N Aminopeptidase P, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 1jawA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1jawA02
2BH3A 3IG4A 2GZ5A 1B6AA 4IKUA 1KP0A 1XGSA 4S01A 1Y1NA 2GGBA 5D6EA 4FLIA 4IKTA 4FO8A 1N51A 5CNXA 4ZWPA 4RZZA 4IU6A 4IPAA 2P98A 4ZWOA 4EGEA 1BN5A 4FO7A 4KM3A 3BITA 4IKSA 1PV9A 2OKNA 2GGCA 3PKBA 2GG2A 2V3ZA 2BWXA 3CB6A 4QR8A 2V3XA 3S6BA 4FUKA 1XNZA 1XGNA 1W7VA 5CDVA 2DFIA 3Q6DA 4PV4A 1C21A 4IDYA 1C23A 5CDEA 1YJ3A 2BWYA 1CHMA 3IU9A 2NQ6A 2Q95A 3L24A 2IW2A 1KQ0A 1WLRA 5JHUA 2GG9A 2GU5A 1WN1A 1XGMA 1WL9A 4U6EA 4U6CA 2BWVA 4Z7MA 5JI6A 4U6JA 3IL0A 3CTZA 1B59A 1YW7A 2GG5A 5CDLA 1C24A 2NQ7A 1M35A 3D27A 2GG7A 4B28A 1R5HA 1A16A 5CIKA 3PKDA 2GU7A 3QOCA 1MATA 5E5BA 1O0XA 3RORA 2BHBA 3L7GA 3PEBA 3PKAA 1WY2A 4U76A 3FMRA 4MATA 4ZNGA 2BWSA 4RZYA 4HXXA 4FKCA 2Q94A 1QXYA 4RGZ1 1YW8A 2BHAA 1XGOA 3FM3A 4S2RP 4JUQA 3FMQA 4U1BA 2V3YA 1YW9A 3TB5A 3PKEA 3OOOA 4U6WA 1R5GA 5D6FA 2ZSGA 3BIQA 4R60A 3I7MA 1C22A 3BIPA 5CE6A 2Q92A 3IU8A 4U75A 1KQ9A 3MX6A 2EVOA 2GG0A 2GG3A 2BWUA 2OAZA 2HOWA 4U73A 1JAWA 3PN9A 1QZYA 2GA2A 2EVMA 3MR1A 2Q93A 2BHCA 2MATA 1W2MA 2Q8KA 2GG8A 4FLJA 2Q96A 2BWTA 2EA2A 2BN7A 4ZWUA 4A6WA 3CB5A 2P9AA 1WBQA 1BOAA 3IU7A 4OOKA 3OVKA 3RVAA 1QXWA 1YVMA 4U71A 1WKMA 4FLLA 4IF7A 2B3HA 2BHDA 4U6ZA 4FLKA 2P99A 5CLSA 2B3KA 2GTXA 5FCHA 3PKCA 4IECA 5FCFA 4S00A 2GU6A 1QXZA 1WL6A 4PNCA 4A6VA 2EVCA 2BWWA 3TAVA 2B3LA 4S2TP 4U70A 1C27A 3O5VA 5E2CA 4U69A 5JFRA 2GU4A 4IKRA 2ADUA 3MATA 2EA4A 2G6PA 1R58A 2BB7A 2V6CA
chains in the Genus database with same CATH superfamily
2BH3A 3IG4A 2GZ5A 1B6AA 4IKUA 1KP0A 1XGSA 4S01A 1Y1NA 2GGBA 5D6EA 4FLIA 4IKTA 4FO8A 1N51A 5CNXA 4ZWPA 4RZZA 4IU6A 4IPAA 2P98A 4ZWOA 4EGEA 1BN5A 4FO7A 4KM3A 3BITA 4IKSA 1PV9A 2OKNA 2GGCA 3PKBA 2GG2A 2V3ZA 2BWXA 3CB6A 4QR8A 2V3XA 3S6BA 4FUKA 1XNZA 1XGNA 1W7VA 5CDVA 2DFIA 3Q6DA 4PV4A 1C21A 4IDYA 1C23A 5CDEA 1YJ3A 2BWYA 1CHMA 3IU9A 2NQ6A 2Q95A 3L24A 2IW2A 1KQ0A 1WLRA 5JHUA 2GG9A 2GU5A 1WN1A 1XGMA 1WL9A 4U6EA 4U6CA 2BWVA 4Z7MA 5JI6A 4U6JA 3IL0A 3CTZA 1B59A 1YW7A 2GG5A 5CDLA 1C24A 2NQ7A 1M35A 3D27A 2GG7A 4B28A 1R5HA 1A16A 5CIKA 3PKDA 2GU7A 3QOCA 1MATA 5E5BA 1O0XA 3RORA 2BHBA 3L7GA 3PEBA 3PKAA 1WY2A 4U76A 3FMRA 4MATA 4ZNGA 2BWSA 4RZYA 4HXXA 4FKCA 2Q94A 1QXYA 4RGZ1 1YW8A 2BHAA 1XGOA 3FM3A 4S2RP 4JUQA 3FMQA 4U1BA 2V3YA 1YW9A 3TB5A 3PKEA 3OOOA 4U6WA 1R5GA 5D6FA 2ZSGA 3BIQA 4R60A 3I7MA 1C22A 3BIPA 5CE6A 2Q92A 3IU8A 4U75A 1KQ9A 3MX6A 2EVOA 2GG0A 2GG3A 2BWUA 2OAZA 2HOWA 4U73A 1JAWA 3PN9A 1QZYA 2GA2A 2EVMA 3MR1A 2Q93A 2BHCA 2MATA 1W2MA 2Q8KA 2GG8A 4FLJA 2Q96A 2BWTA 2EA2A 2BN7A 4ZWUA 4A6WA 3CB5A 2P9AA 1WBQA 1BOAA 3IU7A 4OOKA 3OVKA 3RVAA 1QXWA 1YVMA 4U71A 1WKMA 4FLLA 4IF7A 2B3HA 2BHDA 4U6ZA 4FLKA 2P99A 5CLSA 2B3KA 2GTXA 5FCHA 3PKCA 4IECA 5FCFA 4S00A 2GU6A 1QXZA 1WL6A 4PNCA 4A6VA 2EVCA 2BWWA 3TAVA 2B3LA 4S2TP 4U70A 1C27A 3O5VA 5E2CA 4U69A 5JFRA 2GU4A 4IKRA 2ADUA 3MATA 2EA4A 2G6PA 1R58A 2BB7A 2V6CA
chains in the Genus database with same CATH topology
2BH3A 3IG4A 2GZ5A 1B6AA 4IKUA 1KP0A 1XGSA 4S01A 1Y1NA 2GGBA 5D6EA 4FLIA 4IKTA 4FO8A 1N51A 5CNXA 4ZWPA 4RZZA 4IU6A 4IPAA 2P98A 4ZWOA 4EGEA 1BN5A 4FO7A 4KM3A 3BITA 4IKSA 1PV9A 2OKNA 2GGCA 3PKBA 2GG2A 2V3ZA 2BWXA 3CB6A 4QR8A 2V3XA 3S6BA 4FUKA 1XNZA 1XGNA 1W7VA 5CDVA 2DFIA 3Q6DA 4PV4A 1C21A 4IDYA 1C23A 5CDEA 1YJ3A 2BWYA 1CHMA 3IU9A 2NQ6A 2Q95A 3L24A 2IW2A 1KQ0A 1WLRA 5JHUA 2GG9A 2GU5A 1WN1A 1XGMA 1WL9A 4U6EA 4U6CA 2BWVA 4Z7MA 5JI6A 4U6JA 3IL0A 3CTZA 1B59A 1YW7A 2GG5A 5CDLA 1C24A 2NQ7A 1M35A 3D27A 2GG7A 4B28A 1R5HA 1A16A 5CIKA 3PKDA 2GU7A 3QOCA 1MATA 5E5BA 1O0XA 3RORA 2BHBA 3L7GA 3PEBA 3PKAA 1WY2A 4U76A 3FMRA 4MATA 4ZNGA 2BWSA 4RZYA 4HXXA 4FKCA 2Q94A 1QXYA 4RGZ1 1YW8A 2BHAA 1XGOA 3FM3A 4S2RP 4JUQA 3FMQA 4U1BA 2V3YA 1YW9A 3TB5A 3PKEA 3OOOA 4U6WA 1R5GA 5D6FA 2ZSGA 3BIQA 4R60A 3I7MA 1C22A 3BIPA 5CE6A 2Q92A 3IU8A 4U75A 1KQ9A 3MX6A 2EVOA 2GG0A 2GG3A 2BWUA 2OAZA 2HOWA 4U73A 1JAWA 3PN9A 1QZYA 2GA2A 2EVMA 3MR1A 2Q93A 2BHCA 2MATA 1W2MA 2Q8KA 2GG8A 4FLJA 2Q96A 2BWTA 2EA2A 2BN7A 4ZWUA 4A6WA 3CB5A 2P9AA 1WBQA 1BOAA 3IU7A 4OOKA 3OVKA 3RVAA 1QXWA 1YVMA 4U71A 1WKMA 4FLLA 4IF7A 2B3HA 2BHDA 4U6ZA 4FLKA 2P99A 5CLSA 2B3KA 2GTXA 5FCHA 3PKCA 4IECA 5FCFA 4S00A 2GU6A 1QXZA 1WL6A 4PNCA 4A6VA 2EVCA 2BWWA 3TAVA 2B3LA 4S2TP 4U70A 1C27A 3O5VA 5E2CA 4U69A 5JFRA 2GU4A 4IKRA 2ADUA 3MATA 2EA4A 2G6PA 1R58A 2BB7A 2V6CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BH3 A;  3IG4 A;  2GZ5 A;  1B6A A;  4IKU A;  1KP0 A;  1XGS A;  4S01 A;  1Y1N A;  2GGB A;  5D6E A;  4FLI A;  4IKT A;  4FO8 A;  1N51 A;  5CNX A;  4ZWP A;  4RZZ A;  4IU6 A;  4IPA A;  2P98 A;  4ZWO A;  4EGE A;  1BN5 A;  4FO7 A;  4KM3 A;  3BIT A;  4IKS A;  1PV9 A;  2OKN A;  2GGC A;  3PKB A;  2GG2 A;  2V3Z A;  2BWX A;  3CB6 A;  4QR8 A;  2V3X A;  3S6B A;  4FUK A;  1XNZ A;  1XGN A;  1W7V A;  5CDV A;  2DFI A;  3Q6D A;  4PV4 A;  1C21 A;  4IDY A;  1C23 A;  5CDE A;  1YJ3 A;  2BWY A;  1CHM A;  3IU9 A;  2NQ6 A;  2Q95 A;  3L24 A;  2IW2 A;  1KQ0 A;  1WLR A;  5JHU A;  2GG9 A;  2GU5 A;  1WN1 A;  1XGM A;  1WL9 A;  4U6E A;  4U6C A;  2BWV A;  4Z7M A;  5JI6 A;  4U6J A;  3IL0 A;  3CTZ A;  1B59 A;  1YW7 A;  2GG5 A;  5CDL A;  1C24 A;  2NQ7 A;  1M35 A;  3D27 A;  2GG7 A;  4B28 A;  1R5H A;  1A16 A;  5CIK A;  3PKD A;  2GU7 A;  3QOC A;  1MAT A;  5E5B A;  1O0X A;  3ROR A;  2BHB A;  3L7G A;  3PEB A;  3PKA A;  1WY2 A;  4U76 A;  3FMR A;  4MAT A;  4ZNG A;  2BWS A;  4RZY A;  4HXX A;  4FKC A;  2Q94 A;  1QXY A;  4RGZ 1;  1YW8 A;  2BHA A;  1XGO A;  3FM3 A;  4S2R P;  4JUQ A;  3FMQ A;  4U1B A;  2V3Y A;  1YW9 A;  3TB5 A;  3PKE A;  3OOO A;  4U6W A;  1R5G A;  5D6F A;  2ZSG A;  3BIQ A;  4R60 A;  3I7M A;  1C22 A;  3BIP A;  5CE6 A;  2Q92 A;  3IU8 A;  4U75 A;  1KQ9 A;  3MX6 A;  2EVO A;  2GG0 A;  2GG3 A;  2BWU A;  2OAZ A;  2HOW A;  4U73 A;  1JAW A;  3PN9 A;  1QZY A;  2GA2 A;  2EVM A;  3MR1 A;  2Q93 A;  2BHC A;  2MAT A;  1W2M A;  2Q8K A;  2GG8 A;  4FLJ A;  2Q96 A;  2BWT A;  2EA2 A;  2BN7 A;  4ZWU A;  4A6W A;  3CB5 A;  2P9A A;  1WBQ A;  1BOA A;  3IU7 A;  4OOK A;  3OVK A;  3RVA A;  1QXW A;  1YVM A;  4U71 A;  1WKM A;  4FLL A;  4IF7 A;  2B3H A;  2BHD A;  4U6Z A;  4FLK A;  2P99 A;  5CLS A;  2B3K A;  2GTX A;  5FCH A;  3PKC A;  4IEC A;  5FCF A;  4S00 A;  2GU6 A;  1QXZ A;  1WL6 A;  4PNC A;  4A6V A;  2EVC A;  2BWW A;  3TAV A;  2B3L A;  4S2T P;  4U70 A;  1C27 A;  3O5V A;  5E2C A;  4U69 A;  5JFR A;  2GU4 A;  4IKR A;  2ADU A;  3MAT A;  2EA4 A;  2G6P A;  1R58 A;  2BB7 A;  2V6C A; 
#chains in the Genus database with same CATH topology
 2BH3 A;  3IG4 A;  2GZ5 A;  1B6A A;  4IKU A;  1KP0 A;  1XGS A;  4S01 A;  1Y1N A;  2GGB A;  5D6E A;  4FLI A;  4IKT A;  4FO8 A;  1N51 A;  5CNX A;  4ZWP A;  4RZZ A;  4IU6 A;  4IPA A;  2P98 A;  4ZWO A;  4EGE A;  1BN5 A;  4FO7 A;  4KM3 A;  3BIT A;  4IKS A;  1PV9 A;  2OKN A;  2GGC A;  3PKB A;  2GG2 A;  2V3Z A;  2BWX A;  3CB6 A;  4QR8 A;  2V3X A;  3S6B A;  4FUK A;  1XNZ A;  1XGN A;  1W7V A;  5CDV A;  2DFI A;  3Q6D A;  4PV4 A;  1C21 A;  4IDY A;  1C23 A;  5CDE A;  1YJ3 A;  2BWY A;  1CHM A;  3IU9 A;  2NQ6 A;  2Q95 A;  3L24 A;  2IW2 A;  1KQ0 A;  1WLR A;  5JHU A;  2GG9 A;  2GU5 A;  1WN1 A;  1XGM A;  1WL9 A;  4U6E A;  4U6C A;  2BWV A;  4Z7M A;  5JI6 A;  4U6J A;  3IL0 A;  3CTZ A;  1B59 A;  1YW7 A;  2GG5 A;  5CDL A;  1C24 A;  2NQ7 A;  1M35 A;  3D27 A;  2GG7 A;  4B28 A;  1R5H A;  1A16 A;  5CIK A;  3PKD A;  2GU7 A;  3QOC A;  1MAT A;  5E5B A;  1O0X A;  3ROR A;  2BHB A;  3L7G A;  3PEB A;  3PKA A;  1WY2 A;  4U76 A;  3FMR A;  4MAT A;  4ZNG A;  2BWS A;  4RZY A;  4HXX A;  4FKC A;  2Q94 A;  1QXY A;  4RGZ 1;  1YW8 A;  2BHA A;  1XGO A;  3FM3 A;  4S2R P;  4JUQ A;  3FMQ A;  4U1B A;  2V3Y A;  1YW9 A;  3TB5 A;  3PKE A;  3OOO A;  4U6W A;  1R5G A;  5D6F A;  2ZSG A;  3BIQ A;  4R60 A;  3I7M A;  1C22 A;  3BIP A;  5CE6 A;  2Q92 A;  3IU8 A;  4U75 A;  1KQ9 A;  3MX6 A;  2EVO A;  2GG0 A;  2GG3 A;  2BWU A;  2OAZ A;  2HOW A;  4U73 A;  1JAW A;  3PN9 A;  1QZY A;  2GA2 A;  2EVM A;  3MR1 A;  2Q93 A;  2BHC A;  2MAT A;  1W2M A;  2Q8K A;  2GG8 A;  4FLJ A;  2Q96 A;  2BWT A;  2EA2 A;  2BN7 A;  4ZWU A;  4A6W A;  3CB5 A;  2P9A A;  1WBQ A;  1BOA A;  3IU7 A;  4OOK A;  3OVK A;  3RVA A;  1QXW A;  1YVM A;  4U71 A;  1WKM A;  4FLL A;  4IF7 A;  2B3H A;  2BHD A;  4U6Z A;  4FLK A;  2P99 A;  5CLS A;  2B3K A;  2GTX A;  5FCH A;  3PKC A;  4IEC A;  5FCF A;  4S00 A;  2GU6 A;  1QXZ A;  1WL6 A;  4PNC A;  4A6V A;  2EVC A;  2BWW A;  3TAV A;  2B3L A;  4S2T P;  4U70 A;  1C27 A;  3O5V A;  5E2C A;  4U69 A;  5JFR A;  2GU4 A;  4IKR A;  2ADU A;  3MAT A;  2EA4 A;  2G6P A;  1R58 A;  2BB7 A;  2V6C A; 
#chains in the Genus database with same CATH homology
 2BH3 A;  3IG4 A;  2GZ5 A;  1B6A A;  4IKU A;  1KP0 A;  1XGS A;  4S01 A;  1Y1N A;  2GGB A;  5D6E A;  4FLI A;  4IKT A;  4FO8 A;  1N51 A;  5CNX A;  4ZWP A;  4RZZ A;  4IU6 A;  4IPA A;  2P98 A;  4ZWO A;  4EGE A;  1BN5 A;  4FO7 A;  4KM3 A;  3BIT A;  4IKS A;  1PV9 A;  2OKN A;  2GGC A;  3PKB A;  2GG2 A;  2V3Z A;  2BWX A;  3CB6 A;  4QR8 A;  2V3X A;  3S6B A;  4FUK A;  1XNZ A;  1XGN A;  1W7V A;  5CDV A;  2DFI A;  3Q6D A;  4PV4 A;  1C21 A;  4IDY A;  1C23 A;  5CDE A;  1YJ3 A;  2BWY A;  1CHM A;  3IU9 A;  2NQ6 A;  2Q95 A;  3L24 A;  2IW2 A;  1KQ0 A;  1WLR A;  5JHU A;  2GG9 A;  2GU5 A;  1WN1 A;  1XGM A;  1WL9 A;  4U6E A;  4U6C A;  2BWV A;  4Z7M A;  5JI6 A;  4U6J A;  3IL0 A;  3CTZ A;  1B59 A;  1YW7 A;  2GG5 A;  5CDL A;  1C24 A;  2NQ7 A;  1M35 A;  3D27 A;  2GG7 A;  4B28 A;  1R5H A;  1A16 A;  5CIK A;  3PKD A;  2GU7 A;  3QOC A;  1MAT A;  5E5B A;  1O0X A;  3ROR A;  2BHB A;  3L7G A;  3PEB A;  3PKA A;  1WY2 A;  4U76 A;  3FMR A;  4MAT A;  4ZNG A;  2BWS A;  4RZY A;  4HXX A;  4FKC A;  2Q94 A;  1QXY A;  4RGZ 1;  1YW8 A;  2BHA A;  1XGO A;  3FM3 A;  4S2R P;  4JUQ A;  3FMQ A;  4U1B A;  2V3Y A;  1YW9 A;  3TB5 A;  3PKE A;  3OOO A;  4U6W A;  1R5G A;  5D6F A;  2ZSG A;  3BIQ A;  4R60 A;  3I7M A;  1C22 A;  3BIP A;  5CE6 A;  2Q92 A;  3IU8 A;  4U75 A;  1KQ9 A;  3MX6 A;  2EVO A;  2GG0 A;  2GG3 A;  2BWU A;  2OAZ A;  2HOW A;  4U73 A;  1JAW A;  3PN9 A;  1QZY A;  2GA2 A;  2EVM A;  3MR1 A;  2Q93 A;  2BHC A;  2MAT A;  1W2M A;  2Q8K A;  2GG8 A;  4FLJ A;  2Q96 A;  2BWT A;  2EA2 A;  2BN7 A;  4ZWU A;  4A6W A;  3CB5 A;  2P9A A;  1WBQ A;  1BOA A;  3IU7 A;  4OOK A;  3OVK A;  3RVA A;  1QXW A;  1YVM A;  4U71 A;  1WKM A;  4FLL A;  4IF7 A;  2B3H A;  2BHD A;  4U6Z A;  4FLK A;  2P99 A;  5CLS A;  2B3K A;  2GTX A;  5FCH A;  3PKC A;  4IEC A;  5FCF A;  4S00 A;  2GU6 A;  1QXZ A;  1WL6 A;  4PNC A;  4A6V A;  2EVC A;  2BWW A;  3TAV A;  2B3L A;  4S2T P;  4U70 A;  1C27 A;  3O5V A;  5E2C A;  4U69 A;  5JFR A;  2GU4 A;  4IKR A;  2ADU A;  3MAT A;  2EA4 A;  2G6P A;  1R58 A;  2BB7 A;  2V6C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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