1PV9A

Prolidase from pyrococcus furiosus
Total Genus 112
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
112
sequence length
338
structure length
337
Chain Sequence
LVKFMDENSIDRVFIAKPVNVYYFSGTSPLGGGYIIVDGDEATLYVPELEYEMAKEESKLPVVKFKKFDEIYEILKNTETLGIEGTLSYSMVENFKEKSVKEFKKIDDVIKDLRIIKTKEEIEIIEKACEIADKAVMAAIEEITEGKREREVAAKVEYLMKMNGAEKPAFDTIIASGHRSALPHGVASDKRIERGDLVVIDLGALYNHYNSDITRTIVVGSPNEKQREIYEIVLEAQKRAVEAAKPGMTAKELDSIAREIIKEYGYGDYFIHSLGHGVGLEIHEWPRISQYDETVLKEGMVITIEPGIYIPKLGGVRIEDTVLITENGAKRLTKTER
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structure of the Prolidase from Pyrococcus furiosus.
pubmed doi rcsb
molecule tags Hydrolase
source organism Pyrococcus furiosus
molecule keywords Xaa-Pro dipeptidase
total genus 112
structure length 337
sequence length 338
chains with identical sequence B
ec nomenclature ec 3.4.13.9: Xaa-Pro dipeptidase.
pdb deposition date 2003-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 1pv9A01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1pv9A02
4S2TP 3BITA 4S01A 2GGCA 3D27A 1XGMA 2EA4A 1BOAA 5CNXA 1W2MA 1BN5A 2EVCA 2EVOA 5D6FA 2NQ6A 2Q94A 1N51A 1XGNA 2G6PA 3PEBA 4FO8A 4QR8A 2B3LA 3CTZA 2OAZA 1C22A 2B3HA 1C24A 1R58A 1WL9A 2BHBA 2P98A 2P9AA 4FLIA 4U6JA 4U6EA 5CLSA 4PNCA 3PKEA 2HOWA 3IU9A 5E5BA 1C23A 3PKCA 4IF7A 2BHDA 4FLJA 3FM3A 2GU4A 2GG9A 5E2CA 2ZSGA 4FO7A 3TAVA 5CE6A 1JAWA 5CDEA 3TB5A 1WN1A 3MX6A 4IKSA 3OVKA 4EGEA 1O0XA 2GG8A 3PKDA 3L7GA 4U70A 2OKNA 2GG0A 4FKCA 5CDLA 3IU7A 2BWYA 4IECA 1XGSA 2BB7A 4RZZA 2BN7A 4JUQA 5JI6A 5JFRA 1WY2A 3RVAA 4B28A 3S6BA 4RGZ1 4FUKA 2BWTA 4MATA 2GG3A 3IL0A 4U1BA 1YW7A 1C21A 1YJ3A 1QXYA 2BWSA 2GU6A 3PKBA 3BIQA 4KM3A 1XGOA 4U6CA 2GTXA 2BHAA 2BH3A 5JHUA 2GU5A 4PV4A 2GGBA 2Q96A 2MATA 5CIKA 3PN9A 1YVMA 2NQ7A 5FCHA 1MATA 3O5VA 2B3KA 2P99A 4U75A 2EA2A 2GG7A 1C27A 4RZYA 2V3ZA 3IU8A 3FMQA 1KQ0A 4FLLA 2GU7A 1W7VA 3Q6DA 2GG5A 1WL6A 5FCFA 5D6EA 2BWWA 2BWUA 3MR1A 1PV9A 1A16A 3OOOA 2Q93A 2ADUA 1WKMA 4U6ZA 3L24A 3RORA 5CDVA 4IKTA 4IPAA 4ZNGA 4U76A 1YW8A 4R60A 2V6CA 1WLRA 1KQ9A 4ZWOA 2Q92A 3PKAA 4HXXA 2Q8KA 4A6WA 1R5HA 1R5GA 4Z7MA 1XNZA 4U73A 1B6AA 1Y1NA 1QXZA 1B59A 2EVMA 2V3YA 3CB5A 2GA2A 4U6WA 1KP0A 2BHCA 2GG2A 3BIPA 3I7MA 2GZ5A 4ZWUA 3CB6A 2Q95A 2V3XA 4S00A 1QZYA 1YW9A 3MATA 4OOKA 3QOCA 4FLKA 1M35A 4S2RP 4IU6A 2BWXA 4IKUA 4A6VA 4IKRA 1QXWA 3IG4A 2BWVA 3FMRA 4IDYA 1CHMA 1WBQA 2DFIA 4U71A 2IW2A 4ZWPA 4U69A
chains in the Genus database with same CATH superfamily
4S2TP 3BITA 4S01A 2GGCA 3D27A 1XGMA 2EA4A 1BOAA 5CNXA 1W2MA 1BN5A 2EVCA 2EVOA 5D6FA 2NQ6A 2Q94A 1N51A 1XGNA 2G6PA 3PEBA 4FO8A 4QR8A 2B3LA 3CTZA 2OAZA 1C22A 2B3HA 1C24A 1R58A 1WL9A 2BHBA 2P98A 2P9AA 4FLIA 4U6JA 4U6EA 5CLSA 4PNCA 3PKEA 2HOWA 3IU9A 5E5BA 1C23A 3PKCA 4IF7A 2BHDA 4FLJA 3FM3A 2GU4A 2GG9A 5E2CA 2ZSGA 4FO7A 3TAVA 5CE6A 1JAWA 5CDEA 3TB5A 1WN1A 3MX6A 4IKSA 3OVKA 4EGEA 1O0XA 2GG8A 3PKDA 3L7GA 4U70A 2OKNA 2GG0A 4FKCA 5CDLA 3IU7A 2BWYA 4IECA 1XGSA 2BB7A 4RZZA 2BN7A 4JUQA 5JI6A 5JFRA 1WY2A 3RVAA 4B28A 3S6BA 4RGZ1 4FUKA 2BWTA 4MATA 2GG3A 3IL0A 4U1BA 1YW7A 1C21A 1YJ3A 1QXYA 2BWSA 2GU6A 3PKBA 3BIQA 4KM3A 1XGOA 4U6CA 2GTXA 2BHAA 2BH3A 5JHUA 2GU5A 4PV4A 2GGBA 2Q96A 2MATA 5CIKA 3PN9A 1YVMA 2NQ7A 5FCHA 1MATA 3O5VA 2B3KA 2P99A 4U75A 2EA2A 2GG7A 1C27A 4RZYA 2V3ZA 3IU8A 3FMQA 1KQ0A 4FLLA 2GU7A 1W7VA 3Q6DA 2GG5A 1WL6A 5FCFA 5D6EA 2BWWA 2BWUA 3MR1A 1PV9A 1A16A 3OOOA 2Q93A 2ADUA 1WKMA 4U6ZA 3L24A 3RORA 5CDVA 4IKTA 4IPAA 4ZNGA 4U76A 1YW8A 4R60A 2V6CA 1WLRA 1KQ9A 4ZWOA 2Q92A 3PKAA 4HXXA 2Q8KA 4A6WA 1R5HA 1R5GA 4Z7MA 1XNZA 4U73A 1B6AA 1Y1NA 1QXZA 1B59A 2EVMA 2V3YA 3CB5A 2GA2A 4U6WA 1KP0A 2BHCA 2GG2A 3BIPA 3I7MA 2GZ5A 4ZWUA 3CB6A 2Q95A 2V3XA 4S00A 1QZYA 1YW9A 3MATA 4OOKA 3QOCA 4FLKA 1M35A 4S2RP 4IU6A 2BWXA 4IKUA 4A6VA 4IKRA 1QXWA 3IG4A 2BWVA 3FMRA 4IDYA 1CHMA 1WBQA 2DFIA 4U71A 2IW2A 4ZWPA 4U69A
chains in the Genus database with same CATH topology
4S2TP 3BITA 4S01A 2GGCA 3D27A 1XGMA 2EA4A 1BOAA 5CNXA 1W2MA 1BN5A 2EVCA 2EVOA 5D6FA 2NQ6A 2Q94A 1N51A 1XGNA 2G6PA 3PEBA 4FO8A 4QR8A 2B3LA 3CTZA 2OAZA 1C22A 2B3HA 1C24A 1R58A 1WL9A 2BHBA 2P98A 2P9AA 4FLIA 4U6JA 4U6EA 5CLSA 4PNCA 3PKEA 2HOWA 3IU9A 5E5BA 1C23A 3PKCA 4IF7A 2BHDA 4FLJA 3FM3A 2GU4A 2GG9A 5E2CA 2ZSGA 4FO7A 3TAVA 5CE6A 1JAWA 5CDEA 3TB5A 1WN1A 3MX6A 4IKSA 3OVKA 4EGEA 1O0XA 2GG8A 3PKDA 3L7GA 4U70A 2OKNA 2GG0A 4FKCA 5CDLA 3IU7A 2BWYA 4IECA 1XGSA 2BB7A 4RZZA 2BN7A 4JUQA 5JI6A 5JFRA 1WY2A 3RVAA 4B28A 3S6BA 4RGZ1 4FUKA 2BWTA 4MATA 2GG3A 3IL0A 4U1BA 1YW7A 1C21A 1YJ3A 1QXYA 2BWSA 2GU6A 3PKBA 3BIQA 4KM3A 1XGOA 4U6CA 2GTXA 2BHAA 2BH3A 5JHUA 2GU5A 4PV4A 2GGBA 2Q96A 2MATA 5CIKA 3PN9A 1YVMA 2NQ7A 5FCHA 1MATA 3O5VA 2B3KA 2P99A 4U75A 2EA2A 2GG7A 1C27A 4RZYA 2V3ZA 3IU8A 3FMQA 1KQ0A 4FLLA 2GU7A 1W7VA 3Q6DA 2GG5A 1WL6A 5FCFA 5D6EA 2BWWA 2BWUA 3MR1A 1PV9A 1A16A 3OOOA 2Q93A 2ADUA 1WKMA 4U6ZA 3L24A 3RORA 5CDVA 4IKTA 4IPAA 4ZNGA 4U76A 1YW8A 4R60A 2V6CA 1WLRA 1KQ9A 4ZWOA 2Q92A 3PKAA 4HXXA 2Q8KA 4A6WA 1R5HA 1R5GA 4Z7MA 1XNZA 4U73A 1B6AA 1Y1NA 1QXZA 1B59A 2EVMA 2V3YA 3CB5A 2GA2A 4U6WA 1KP0A 2BHCA 2GG2A 3BIPA 3I7MA 2GZ5A 4ZWUA 3CB6A 2Q95A 2V3XA 4S00A 1QZYA 1YW9A 3MATA 4OOKA 3QOCA 4FLKA 1M35A 4S2RP 4IU6A 2BWXA 4IKUA 4A6VA 4IKRA 1QXWA 3IG4A 2BWVA 3FMRA 4IDYA 1CHMA 1WBQA 2DFIA 4U71A 2IW2A 4ZWPA 4U69A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4S2T P;  3BIT A;  4S01 A;  2GGC A;  3D27 A;  1XGM A;  2EA4 A;  1BOA A;  5CNX A;  1W2M A;  1BN5 A;  2EVC A;  2EVO A;  5D6F A;  2NQ6 A;  2Q94 A;  1N51 A;  1XGN A;  2G6P A;  3PEB A;  4FO8 A;  4QR8 A;  2B3L A;  3CTZ A;  2OAZ A;  1C22 A;  2B3H A;  1C24 A;  1R58 A;  1WL9 A;  2BHB A;  2P98 A;  2P9A A;  4FLI A;  4U6J A;  4U6E A;  5CLS A;  4PNC A;  3PKE A;  2HOW A;  3IU9 A;  5E5B A;  1C23 A;  3PKC A;  4IF7 A;  2BHD A;  4FLJ A;  3FM3 A;  2GU4 A;  2GG9 A;  5E2C A;  2ZSG A;  4FO7 A;  3TAV A;  5CE6 A;  1JAW A;  5CDE A;  3TB5 A;  1WN1 A;  3MX6 A;  4IKS A;  3OVK A;  4EGE A;  1O0X A;  2GG8 A;  3PKD A;  3L7G A;  4U70 A;  2OKN A;  2GG0 A;  4FKC A;  5CDL A;  3IU7 A;  2BWY A;  4IEC A;  1XGS A;  2BB7 A;  4RZZ A;  2BN7 A;  4JUQ A;  5JI6 A;  5JFR A;  1WY2 A;  3RVA A;  4B28 A;  3S6B A;  4RGZ 1;  4FUK A;  2BWT A;  4MAT A;  2GG3 A;  3IL0 A;  4U1B A;  1YW7 A;  1C21 A;  1YJ3 A;  1QXY A;  2BWS A;  2GU6 A;  3PKB A;  3BIQ A;  4KM3 A;  1XGO A;  4U6C A;  2GTX A;  2BHA A;  2BH3 A;  5JHU A;  2GU5 A;  4PV4 A;  2GGB A;  2Q96 A;  2MAT A;  5CIK A;  3PN9 A;  1YVM A;  2NQ7 A;  5FCH A;  1MAT A;  3O5V A;  2B3K A;  2P99 A;  4U75 A;  2EA2 A;  2GG7 A;  1C27 A;  4RZY A;  2V3Z A;  3IU8 A;  3FMQ A;  1KQ0 A;  4FLL A;  2GU7 A;  1W7V A;  3Q6D A;  2GG5 A;  1WL6 A;  5FCF A;  5D6E A;  2BWW A;  2BWU A;  3MR1 A;  1PV9 A;  1A16 A;  3OOO A;  2Q93 A;  2ADU A;  1WKM A;  4U6Z A;  3L24 A;  3ROR A;  5CDV A;  4IKT A;  4IPA A;  4ZNG A;  4U76 A;  1YW8 A;  4R60 A;  2V6C A;  1WLR A;  1KQ9 A;  4ZWO A;  2Q92 A;  3PKA A;  4HXX A;  2Q8K A;  4A6W A;  1R5H A;  1R5G A;  4Z7M A;  1XNZ A;  4U73 A;  1B6A A;  1Y1N A;  1QXZ A;  1B59 A;  2EVM A;  2V3Y A;  3CB5 A;  2GA2 A;  4U6W A;  1KP0 A;  2BHC A;  2GG2 A;  3BIP A;  3I7M A;  2GZ5 A;  4ZWU A;  3CB6 A;  2Q95 A;  2V3X A;  4S00 A;  1QZY A;  1YW9 A;  3MAT A;  4OOK A;  3QOC A;  4FLK A;  1M35 A;  4S2R P;  4IU6 A;  2BWX A;  4IKU A;  4A6V A;  4IKR A;  1QXW A;  3IG4 A;  2BWV A;  3FMR A;  4IDY A;  1CHM A;  1WBQ A;  2DFI A;  4U71 A;  2IW2 A;  4ZWP A;  4U69 A; 
#chains in the Genus database with same CATH topology
 4S2T P;  3BIT A;  4S01 A;  2GGC A;  3D27 A;  1XGM A;  2EA4 A;  1BOA A;  5CNX A;  1W2M A;  1BN5 A;  2EVC A;  2EVO A;  5D6F A;  2NQ6 A;  2Q94 A;  1N51 A;  1XGN A;  2G6P A;  3PEB A;  4FO8 A;  4QR8 A;  2B3L A;  3CTZ A;  2OAZ A;  1C22 A;  2B3H A;  1C24 A;  1R58 A;  1WL9 A;  2BHB A;  2P98 A;  2P9A A;  4FLI A;  4U6J A;  4U6E A;  5CLS A;  4PNC A;  3PKE A;  2HOW A;  3IU9 A;  5E5B A;  1C23 A;  3PKC A;  4IF7 A;  2BHD A;  4FLJ A;  3FM3 A;  2GU4 A;  2GG9 A;  5E2C A;  2ZSG A;  4FO7 A;  3TAV A;  5CE6 A;  1JAW A;  5CDE A;  3TB5 A;  1WN1 A;  3MX6 A;  4IKS A;  3OVK A;  4EGE A;  1O0X A;  2GG8 A;  3PKD A;  3L7G A;  4U70 A;  2OKN A;  2GG0 A;  4FKC A;  5CDL A;  3IU7 A;  2BWY A;  4IEC A;  1XGS A;  2BB7 A;  4RZZ A;  2BN7 A;  4JUQ A;  5JI6 A;  5JFR A;  1WY2 A;  3RVA A;  4B28 A;  3S6B A;  4RGZ 1;  4FUK A;  2BWT A;  4MAT A;  2GG3 A;  3IL0 A;  4U1B A;  1YW7 A;  1C21 A;  1YJ3 A;  1QXY A;  2BWS A;  2GU6 A;  3PKB A;  3BIQ A;  4KM3 A;  1XGO A;  4U6C A;  2GTX A;  2BHA A;  2BH3 A;  5JHU A;  2GU5 A;  4PV4 A;  2GGB A;  2Q96 A;  2MAT A;  5CIK A;  3PN9 A;  1YVM A;  2NQ7 A;  5FCH A;  1MAT A;  3O5V A;  2B3K A;  2P99 A;  4U75 A;  2EA2 A;  2GG7 A;  1C27 A;  4RZY A;  2V3Z A;  3IU8 A;  3FMQ A;  1KQ0 A;  4FLL A;  2GU7 A;  1W7V A;  3Q6D A;  2GG5 A;  1WL6 A;  5FCF A;  5D6E A;  2BWW A;  2BWU A;  3MR1 A;  1PV9 A;  1A16 A;  3OOO A;  2Q93 A;  2ADU A;  1WKM A;  4U6Z A;  3L24 A;  3ROR A;  5CDV A;  4IKT A;  4IPA A;  4ZNG A;  4U76 A;  1YW8 A;  4R60 A;  2V6C A;  1WLR A;  1KQ9 A;  4ZWO A;  2Q92 A;  3PKA A;  4HXX A;  2Q8K A;  4A6W A;  1R5H A;  1R5G A;  4Z7M A;  1XNZ A;  4U73 A;  1B6A A;  1Y1N A;  1QXZ A;  1B59 A;  2EVM A;  2V3Y A;  3CB5 A;  2GA2 A;  4U6W A;  1KP0 A;  2BHC A;  2GG2 A;  3BIP A;  3I7M A;  2GZ5 A;  4ZWU A;  3CB6 A;  2Q95 A;  2V3X A;  4S00 A;  1QZY A;  1YW9 A;  3MAT A;  4OOK A;  3QOC A;  4FLK A;  1M35 A;  4S2R P;  4IU6 A;  2BWX A;  4IKU A;  4A6V A;  4IKR A;  1QXW A;  3IG4 A;  2BWV A;  3FMR A;  4IDY A;  1CHM A;  1WBQ A;  2DFI A;  4U71 A;  2IW2 A;  4ZWP A;  4U69 A; 
#chains in the Genus database with same CATH homology
 4S2T P;  3BIT A;  4S01 A;  2GGC A;  3D27 A;  1XGM A;  2EA4 A;  1BOA A;  5CNX A;  1W2M A;  1BN5 A;  2EVC A;  2EVO A;  5D6F A;  2NQ6 A;  2Q94 A;  1N51 A;  1XGN A;  2G6P A;  3PEB A;  4FO8 A;  4QR8 A;  2B3L A;  3CTZ A;  2OAZ A;  1C22 A;  2B3H A;  1C24 A;  1R58 A;  1WL9 A;  2BHB A;  2P98 A;  2P9A A;  4FLI A;  4U6J A;  4U6E A;  5CLS A;  4PNC A;  3PKE A;  2HOW A;  3IU9 A;  5E5B A;  1C23 A;  3PKC A;  4IF7 A;  2BHD A;  4FLJ A;  3FM3 A;  2GU4 A;  2GG9 A;  5E2C A;  2ZSG A;  4FO7 A;  3TAV A;  5CE6 A;  1JAW A;  5CDE A;  3TB5 A;  1WN1 A;  3MX6 A;  4IKS A;  3OVK A;  4EGE A;  1O0X A;  2GG8 A;  3PKD A;  3L7G A;  4U70 A;  2OKN A;  2GG0 A;  4FKC A;  5CDL A;  3IU7 A;  2BWY A;  4IEC A;  1XGS A;  2BB7 A;  4RZZ A;  2BN7 A;  4JUQ A;  5JI6 A;  5JFR A;  1WY2 A;  3RVA A;  4B28 A;  3S6B A;  4RGZ 1;  4FUK A;  2BWT A;  4MAT A;  2GG3 A;  3IL0 A;  4U1B A;  1YW7 A;  1C21 A;  1YJ3 A;  1QXY A;  2BWS A;  2GU6 A;  3PKB A;  3BIQ A;  4KM3 A;  1XGO A;  4U6C A;  2GTX A;  2BHA A;  2BH3 A;  5JHU A;  2GU5 A;  4PV4 A;  2GGB A;  2Q96 A;  2MAT A;  5CIK A;  3PN9 A;  1YVM A;  2NQ7 A;  5FCH A;  1MAT A;  3O5V A;  2B3K A;  2P99 A;  4U75 A;  2EA2 A;  2GG7 A;  1C27 A;  4RZY A;  2V3Z A;  3IU8 A;  3FMQ A;  1KQ0 A;  4FLL A;  2GU7 A;  1W7V A;  3Q6D A;  2GG5 A;  1WL6 A;  5FCF A;  5D6E A;  2BWW A;  2BWU A;  3MR1 A;  1PV9 A;  1A16 A;  3OOO A;  2Q93 A;  2ADU A;  1WKM A;  4U6Z A;  3L24 A;  3ROR A;  5CDV A;  4IKT A;  4IPA A;  4ZNG A;  4U76 A;  1YW8 A;  4R60 A;  2V6C A;  1WLR A;  1KQ9 A;  4ZWO A;  2Q92 A;  3PKA A;  4HXX A;  2Q8K A;  4A6W A;  1R5H A;  1R5G A;  4Z7M A;  1XNZ A;  4U73 A;  1B6A A;  1Y1N A;  1QXZ A;  1B59 A;  2EVM A;  2V3Y A;  3CB5 A;  2GA2 A;  4U6W A;  1KP0 A;  2BHC A;  2GG2 A;  3BIP A;  3I7M A;  2GZ5 A;  4ZWU A;  3CB6 A;  2Q95 A;  2V3X A;  4S00 A;  1QZY A;  1YW9 A;  3MAT A;  4OOK A;  3QOC A;  4FLK A;  1M35 A;  4S2R P;  4IU6 A;  2BWX A;  4IKU A;  4A6V A;  4IKR A;  1QXW A;  3IG4 A;  2BWV A;  3FMR A;  4IDY A;  1CHM A;  1WBQ A;  2DFI A;  4U71 A;  2IW2 A;  4ZWP A;  4U69 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...