2HOWA

Dipeptidase (ph0974) from pyrococcus horikoshii ot3
Total Genus 124
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
124
sequence length
356
structure length
356
Chain Sequence
MRLEKFIHLLGERGFDGALISPGTNLYYLTGLRLHEVGERLAILAVSAEGDYRFLAPSLYENVVNNFPATFWHDGENPYAKLREILEELGISKGRILIEDTMRADWLIGIMKLGKFTFQPLSSLIKELRMIKDKEEVKMMEHASRIADKVFEEILTWDLIGMKERELALKIELLIRELSDGIAFEPIVASGENAANPHHEPGERKIRKGDIIILDYGARWKGYCSDITRTIGLGELDERLVKIYEVVKDAQESAFKAVREGIKAKDVDSRAREVISKAGYGEYFIHRTGHGLGLDVHEEPYIGPDGEVILKNGMTFTIEPGIYVPGLGGVRIEDDIVVDEGKGRRLTKAERELIIL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Dipeptidase (PH0974) from Pyrococcus Horikoshii Ot3
rcsb
molecule tags Hydrolase
source organism Pyrococcus horikoshii
molecule keywords 356aa long hypothetical dipeptidase
total genus 124
structure length 356
sequence length 356
chains with identical sequence B
ec nomenclature ec 3.4.-.-:
pdb deposition date 2006-07-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 2howA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 2howA02
4RZZA 1XGNA 2BWXA 1QXZA 2GG3A 2GG0A 3IL0A 3IU8A 2OKNA 4IDYA 4FO8A 2BWUA 2BHBA 3D27A 2BHAA 4FKCA 4QR8A 1CHMA 3RVAA 5CDVA 1WL9A 4FLKA 1XGOA 1O0XA 2Q93A 4U70A 1R5GA 3FMRA 2GTXA 3PKCA 4FUKA 4U71A 2P99A 4ZWOA 2BWTA 4ZNGA 1C23A 3OOOA 3IU9A 2V3XA 2IW2A 2B3HA 2EVMA 5CDLA 2EVCA 4HXXA 5E2CA 1B59A 4IKUA 1KP0A 3FM3A 5FCHA 1WKMA 4IKTA 2GG8A 4U69A 2BWVA 5JI6A 2EA4A 1JAWA 1BOAA 2GG7A 3L24A 3CB5A 4A6VA 2BB7A 4KM3A 1WLRA 4IKSA 4IPAA 2BHCA 4B28A 1MATA 3IU7A 5E5BA 2BWYA 3QOCA 5JHUA 3PKBA 4U73A 3PKEA 4ZWUA 2GZ5A 4IKRA 5D6FA 2V3ZA 1PV9A 2ADUA 5CNXA 2EA2A 4FLIA 5CDEA 1YW7A 4S2RP 3BITA 3PKDA 3L7GA 1YW8A 3FMQA 2BH3A 1QZYA 2EVOA 2BHDA 2GG2A 2GU4A 3TB5A 1XNZA 2GGCA 1QXWA 1QXYA 3PEBA 1C24A 5FCFA 3MATA 1M35A 5CE6A 2GU6A 1W7VA 2V6CA 1Y1NA 1W2MA 4U1BA 5D6EA 4U6CA 2BN7A 2NQ7A 1C21A 1XGMA 4IF7A 1YVMA 4OOKA 4R60A 1KQ9A 4U6JA 3S6BA 4S01A 4A6WA 4U76A 1B6AA 1WBQA 2BWSA 1R5HA 1WY2A 2B3KA 4IU6A 1KQ0A 3CTZA 3BIQA 2BWWA 2Q94A 4FLJA 2P9AA 2GGBA 4PV4A 4RGZ1 2B3LA 4U6ZA 2GA2A 2GG5A 1BN5A 3MR1A 2GU5A 2Q95A 1WN1A 2DFIA 4S2TP 2MATA 4JUQA 4IECA 4MATA 3RORA 4Z7MA 2GG9A 2HOWA 3IG4A 2GU7A 2G6PA 1WL6A 5JFRA 3OVKA 2NQ6A 5CLSA 3O5VA 1N51A 1YJ3A 3Q6DA 2P98A 3I7MA 2OAZA 4U6EA 4ZWPA 5CIKA 4PNCA 4U6WA 3PN9A 3CB6A 4S00A 3TAVA 3MX6A 2ZSGA 2Q92A 1R58A 3BIPA 3PKAA 4FLLA 2V3YA 4U75A 1C22A 4RZYA 2Q96A 2Q8KA 4EGEA 4FO7A 1YW9A 1XGSA 1A16A 1C27A
chains in the Genus database with same CATH superfamily
4RZZA 1XGNA 2BWXA 1QXZA 2GG3A 2GG0A 3IL0A 3IU8A 2OKNA 4IDYA 4FO8A 2BWUA 2BHBA 3D27A 2BHAA 4FKCA 4QR8A 1CHMA 3RVAA 5CDVA 1WL9A 4FLKA 1XGOA 1O0XA 2Q93A 4U70A 1R5GA 3FMRA 2GTXA 3PKCA 4FUKA 4U71A 2P99A 4ZWOA 2BWTA 4ZNGA 1C23A 3OOOA 3IU9A 2V3XA 2IW2A 2B3HA 2EVMA 5CDLA 2EVCA 4HXXA 5E2CA 1B59A 4IKUA 1KP0A 3FM3A 5FCHA 1WKMA 4IKTA 2GG8A 4U69A 2BWVA 5JI6A 2EA4A 1JAWA 1BOAA 2GG7A 3L24A 3CB5A 4A6VA 2BB7A 4KM3A 1WLRA 4IKSA 4IPAA 2BHCA 4B28A 1MATA 3IU7A 5E5BA 2BWYA 3QOCA 5JHUA 3PKBA 4U73A 3PKEA 4ZWUA 2GZ5A 4IKRA 5D6FA 2V3ZA 1PV9A 2ADUA 5CNXA 2EA2A 4FLIA 5CDEA 1YW7A 4S2RP 3BITA 3PKDA 3L7GA 1YW8A 3FMQA 2BH3A 1QZYA 2EVOA 2BHDA 2GG2A 2GU4A 3TB5A 1XNZA 2GGCA 1QXWA 1QXYA 3PEBA 1C24A 5FCFA 3MATA 1M35A 5CE6A 2GU6A 1W7VA 2V6CA 1Y1NA 1W2MA 4U1BA 5D6EA 4U6CA 2BN7A 2NQ7A 1C21A 1XGMA 4IF7A 1YVMA 4OOKA 4R60A 1KQ9A 4U6JA 3S6BA 4S01A 4A6WA 4U76A 1B6AA 1WBQA 2BWSA 1R5HA 1WY2A 2B3KA 4IU6A 1KQ0A 3CTZA 3BIQA 2BWWA 2Q94A 4FLJA 2P9AA 2GGBA 4PV4A 4RGZ1 2B3LA 4U6ZA 2GA2A 2GG5A 1BN5A 3MR1A 2GU5A 2Q95A 1WN1A 2DFIA 4S2TP 2MATA 4JUQA 4IECA 4MATA 3RORA 4Z7MA 2GG9A 2HOWA 3IG4A 2GU7A 2G6PA 1WL6A 5JFRA 3OVKA 2NQ6A 5CLSA 3O5VA 1N51A 1YJ3A 3Q6DA 2P98A 3I7MA 2OAZA 4U6EA 4ZWPA 5CIKA 4PNCA 4U6WA 3PN9A 3CB6A 4S00A 3TAVA 3MX6A 2ZSGA 2Q92A 1R58A 3BIPA 3PKAA 4FLLA 2V3YA 4U75A 1C22A 4RZYA 2Q96A 2Q8KA 4EGEA 4FO7A 1YW9A 1XGSA 1A16A 1C27A
chains in the Genus database with same CATH topology
4RZZA 1XGNA 2BWXA 1QXZA 2GG3A 2GG0A 3IL0A 3IU8A 2OKNA 4IDYA 4FO8A 2BWUA 2BHBA 3D27A 2BHAA 4FKCA 4QR8A 1CHMA 3RVAA 5CDVA 1WL9A 4FLKA 1XGOA 1O0XA 2Q93A 4U70A 1R5GA 3FMRA 2GTXA 3PKCA 4FUKA 4U71A 2P99A 4ZWOA 2BWTA 4ZNGA 1C23A 3OOOA 3IU9A 2V3XA 2IW2A 2B3HA 2EVMA 5CDLA 2EVCA 4HXXA 5E2CA 1B59A 4IKUA 1KP0A 3FM3A 5FCHA 1WKMA 4IKTA 2GG8A 4U69A 2BWVA 5JI6A 2EA4A 1JAWA 1BOAA 2GG7A 3L24A 3CB5A 4A6VA 2BB7A 4KM3A 1WLRA 4IKSA 4IPAA 2BHCA 4B28A 1MATA 3IU7A 5E5BA 2BWYA 3QOCA 5JHUA 3PKBA 4U73A 3PKEA 4ZWUA 2GZ5A 4IKRA 5D6FA 2V3ZA 1PV9A 2ADUA 5CNXA 2EA2A 4FLIA 5CDEA 1YW7A 4S2RP 3BITA 3PKDA 3L7GA 1YW8A 3FMQA 2BH3A 1QZYA 2EVOA 2BHDA 2GG2A 2GU4A 3TB5A 1XNZA 2GGCA 1QXWA 1QXYA 3PEBA 1C24A 5FCFA 3MATA 1M35A 5CE6A 2GU6A 1W7VA 2V6CA 1Y1NA 1W2MA 4U1BA 5D6EA 4U6CA 2BN7A 2NQ7A 1C21A 1XGMA 4IF7A 1YVMA 4OOKA 4R60A 1KQ9A 4U6JA 3S6BA 4S01A 4A6WA 4U76A 1B6AA 1WBQA 2BWSA 1R5HA 1WY2A 2B3KA 4IU6A 1KQ0A 3CTZA 3BIQA 2BWWA 2Q94A 4FLJA 2P9AA 2GGBA 4PV4A 4RGZ1 2B3LA 4U6ZA 2GA2A 2GG5A 1BN5A 3MR1A 2GU5A 2Q95A 1WN1A 2DFIA 4S2TP 2MATA 4JUQA 4IECA 4MATA 3RORA 4Z7MA 2GG9A 2HOWA 3IG4A 2GU7A 2G6PA 1WL6A 5JFRA 3OVKA 2NQ6A 5CLSA 3O5VA 1N51A 1YJ3A 3Q6DA 2P98A 3I7MA 2OAZA 4U6EA 4ZWPA 5CIKA 4PNCA 4U6WA 3PN9A 3CB6A 4S00A 3TAVA 3MX6A 2ZSGA 2Q92A 1R58A 3BIPA 3PKAA 4FLLA 2V3YA 4U75A 1C22A 4RZYA 2Q96A 2Q8KA 4EGEA 4FO7A 1YW9A 1XGSA 1A16A 1C27A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RZZ A;  1XGN A;  2BWX A;  1QXZ A;  2GG3 A;  2GG0 A;  3IL0 A;  3IU8 A;  2OKN A;  4IDY A;  4FO8 A;  2BWU A;  2BHB A;  3D27 A;  2BHA A;  4FKC A;  4QR8 A;  1CHM A;  3RVA A;  5CDV A;  1WL9 A;  4FLK A;  1XGO A;  1O0X A;  2Q93 A;  4U70 A;  1R5G A;  3FMR A;  2GTX A;  3PKC A;  4FUK A;  4U71 A;  2P99 A;  4ZWO A;  2BWT A;  4ZNG A;  1C23 A;  3OOO A;  3IU9 A;  2V3X A;  2IW2 A;  2B3H A;  2EVM A;  5CDL A;  2EVC A;  4HXX A;  5E2C A;  1B59 A;  4IKU A;  1KP0 A;  3FM3 A;  5FCH A;  1WKM A;  4IKT A;  2GG8 A;  4U69 A;  2BWV A;  5JI6 A;  2EA4 A;  1JAW A;  1BOA A;  2GG7 A;  3L24 A;  3CB5 A;  4A6V A;  2BB7 A;  4KM3 A;  1WLR A;  4IKS A;  4IPA A;  2BHC A;  4B28 A;  1MAT A;  3IU7 A;  5E5B A;  2BWY A;  3QOC A;  5JHU A;  3PKB A;  4U73 A;  3PKE A;  4ZWU A;  2GZ5 A;  4IKR A;  5D6F A;  2V3Z A;  1PV9 A;  2ADU A;  5CNX A;  2EA2 A;  4FLI A;  5CDE A;  1YW7 A;  4S2R P;  3BIT A;  3PKD A;  3L7G A;  1YW8 A;  3FMQ A;  2BH3 A;  1QZY A;  2EVO A;  2BHD A;  2GG2 A;  2GU4 A;  3TB5 A;  1XNZ A;  2GGC A;  1QXW A;  1QXY A;  3PEB A;  1C24 A;  5FCF A;  3MAT A;  1M35 A;  5CE6 A;  2GU6 A;  1W7V A;  2V6C A;  1Y1N A;  1W2M A;  4U1B A;  5D6E A;  4U6C A;  2BN7 A;  2NQ7 A;  1C21 A;  1XGM A;  4IF7 A;  1YVM A;  4OOK A;  4R60 A;  1KQ9 A;  4U6J A;  3S6B A;  4S01 A;  4A6W A;  4U76 A;  1B6A A;  1WBQ A;  2BWS A;  1R5H A;  1WY2 A;  2B3K A;  4IU6 A;  1KQ0 A;  3CTZ A;  3BIQ A;  2BWW A;  2Q94 A;  4FLJ A;  2P9A A;  2GGB A;  4PV4 A;  4RGZ 1;  2B3L A;  4U6Z A;  2GA2 A;  2GG5 A;  1BN5 A;  3MR1 A;  2GU5 A;  2Q95 A;  1WN1 A;  2DFI A;  4S2T P;  2MAT A;  4JUQ A;  4IEC A;  4MAT A;  3ROR A;  4Z7M A;  2GG9 A;  2HOW A;  3IG4 A;  2GU7 A;  2G6P A;  1WL6 A;  5JFR A;  3OVK A;  2NQ6 A;  5CLS A;  3O5V A;  1N51 A;  1YJ3 A;  3Q6D A;  2P98 A;  3I7M A;  2OAZ A;  4U6E A;  4ZWP A;  5CIK A;  4PNC A;  4U6W A;  3PN9 A;  3CB6 A;  4S00 A;  3TAV A;  3MX6 A;  2ZSG A;  2Q92 A;  1R58 A;  3BIP A;  3PKA A;  4FLL A;  2V3Y A;  4U75 A;  1C22 A;  4RZY A;  2Q96 A;  2Q8K A;  4EGE A;  4FO7 A;  1YW9 A;  1XGS A;  1A16 A;  1C27 A; 
#chains in the Genus database with same CATH topology
 4RZZ A;  1XGN A;  2BWX A;  1QXZ A;  2GG3 A;  2GG0 A;  3IL0 A;  3IU8 A;  2OKN A;  4IDY A;  4FO8 A;  2BWU A;  2BHB A;  3D27 A;  2BHA A;  4FKC A;  4QR8 A;  1CHM A;  3RVA A;  5CDV A;  1WL9 A;  4FLK A;  1XGO A;  1O0X A;  2Q93 A;  4U70 A;  1R5G A;  3FMR A;  2GTX A;  3PKC A;  4FUK A;  4U71 A;  2P99 A;  4ZWO A;  2BWT A;  4ZNG A;  1C23 A;  3OOO A;  3IU9 A;  2V3X A;  2IW2 A;  2B3H A;  2EVM A;  5CDL A;  2EVC A;  4HXX A;  5E2C A;  1B59 A;  4IKU A;  1KP0 A;  3FM3 A;  5FCH A;  1WKM A;  4IKT A;  2GG8 A;  4U69 A;  2BWV A;  5JI6 A;  2EA4 A;  1JAW A;  1BOA A;  2GG7 A;  3L24 A;  3CB5 A;  4A6V A;  2BB7 A;  4KM3 A;  1WLR A;  4IKS A;  4IPA A;  2BHC A;  4B28 A;  1MAT A;  3IU7 A;  5E5B A;  2BWY A;  3QOC A;  5JHU A;  3PKB A;  4U73 A;  3PKE A;  4ZWU A;  2GZ5 A;  4IKR A;  5D6F A;  2V3Z A;  1PV9 A;  2ADU A;  5CNX A;  2EA2 A;  4FLI A;  5CDE A;  1YW7 A;  4S2R P;  3BIT A;  3PKD A;  3L7G A;  1YW8 A;  3FMQ A;  2BH3 A;  1QZY A;  2EVO A;  2BHD A;  2GG2 A;  2GU4 A;  3TB5 A;  1XNZ A;  2GGC A;  1QXW A;  1QXY A;  3PEB A;  1C24 A;  5FCF A;  3MAT A;  1M35 A;  5CE6 A;  2GU6 A;  1W7V A;  2V6C A;  1Y1N A;  1W2M A;  4U1B A;  5D6E A;  4U6C A;  2BN7 A;  2NQ7 A;  1C21 A;  1XGM A;  4IF7 A;  1YVM A;  4OOK A;  4R60 A;  1KQ9 A;  4U6J A;  3S6B A;  4S01 A;  4A6W A;  4U76 A;  1B6A A;  1WBQ A;  2BWS A;  1R5H A;  1WY2 A;  2B3K A;  4IU6 A;  1KQ0 A;  3CTZ A;  3BIQ A;  2BWW A;  2Q94 A;  4FLJ A;  2P9A A;  2GGB A;  4PV4 A;  4RGZ 1;  2B3L A;  4U6Z A;  2GA2 A;  2GG5 A;  1BN5 A;  3MR1 A;  2GU5 A;  2Q95 A;  1WN1 A;  2DFI A;  4S2T P;  2MAT A;  4JUQ A;  4IEC A;  4MAT A;  3ROR A;  4Z7M A;  2GG9 A;  2HOW A;  3IG4 A;  2GU7 A;  2G6P A;  1WL6 A;  5JFR A;  3OVK A;  2NQ6 A;  5CLS A;  3O5V A;  1N51 A;  1YJ3 A;  3Q6D A;  2P98 A;  3I7M A;  2OAZ A;  4U6E A;  4ZWP A;  5CIK A;  4PNC A;  4U6W A;  3PN9 A;  3CB6 A;  4S00 A;  3TAV A;  3MX6 A;  2ZSG A;  2Q92 A;  1R58 A;  3BIP A;  3PKA A;  4FLL A;  2V3Y A;  4U75 A;  1C22 A;  4RZY A;  2Q96 A;  2Q8K A;  4EGE A;  4FO7 A;  1YW9 A;  1XGS A;  1A16 A;  1C27 A; 
#chains in the Genus database with same CATH homology
 4RZZ A;  1XGN A;  2BWX A;  1QXZ A;  2GG3 A;  2GG0 A;  3IL0 A;  3IU8 A;  2OKN A;  4IDY A;  4FO8 A;  2BWU A;  2BHB A;  3D27 A;  2BHA A;  4FKC A;  4QR8 A;  1CHM A;  3RVA A;  5CDV A;  1WL9 A;  4FLK A;  1XGO A;  1O0X A;  2Q93 A;  4U70 A;  1R5G A;  3FMR A;  2GTX A;  3PKC A;  4FUK A;  4U71 A;  2P99 A;  4ZWO A;  2BWT A;  4ZNG A;  1C23 A;  3OOO A;  3IU9 A;  2V3X A;  2IW2 A;  2B3H A;  2EVM A;  5CDL A;  2EVC A;  4HXX A;  5E2C A;  1B59 A;  4IKU A;  1KP0 A;  3FM3 A;  5FCH A;  1WKM A;  4IKT A;  2GG8 A;  4U69 A;  2BWV A;  5JI6 A;  2EA4 A;  1JAW A;  1BOA A;  2GG7 A;  3L24 A;  3CB5 A;  4A6V A;  2BB7 A;  4KM3 A;  1WLR A;  4IKS A;  4IPA A;  2BHC A;  4B28 A;  1MAT A;  3IU7 A;  5E5B A;  2BWY A;  3QOC A;  5JHU A;  3PKB A;  4U73 A;  3PKE A;  4ZWU A;  2GZ5 A;  4IKR A;  5D6F A;  2V3Z A;  1PV9 A;  2ADU A;  5CNX A;  2EA2 A;  4FLI A;  5CDE A;  1YW7 A;  4S2R P;  3BIT A;  3PKD A;  3L7G A;  1YW8 A;  3FMQ A;  2BH3 A;  1QZY A;  2EVO A;  2BHD A;  2GG2 A;  2GU4 A;  3TB5 A;  1XNZ A;  2GGC A;  1QXW A;  1QXY A;  3PEB A;  1C24 A;  5FCF A;  3MAT A;  1M35 A;  5CE6 A;  2GU6 A;  1W7V A;  2V6C A;  1Y1N A;  1W2M A;  4U1B A;  5D6E A;  4U6C A;  2BN7 A;  2NQ7 A;  1C21 A;  1XGM A;  4IF7 A;  1YVM A;  4OOK A;  4R60 A;  1KQ9 A;  4U6J A;  3S6B A;  4S01 A;  4A6W A;  4U76 A;  1B6A A;  1WBQ A;  2BWS A;  1R5H A;  1WY2 A;  2B3K A;  4IU6 A;  1KQ0 A;  3CTZ A;  3BIQ A;  2BWW A;  2Q94 A;  4FLJ A;  2P9A A;  2GGB A;  4PV4 A;  4RGZ 1;  2B3L A;  4U6Z A;  2GA2 A;  2GG5 A;  1BN5 A;  3MR1 A;  2GU5 A;  2Q95 A;  1WN1 A;  2DFI A;  4S2T P;  2MAT A;  4JUQ A;  4IEC A;  4MAT A;  3ROR A;  4Z7M A;  2GG9 A;  2HOW A;  3IG4 A;  2GU7 A;  2G6P A;  1WL6 A;  5JFR A;  3OVK A;  2NQ6 A;  5CLS A;  3O5V A;  1N51 A;  1YJ3 A;  3Q6D A;  2P98 A;  3I7M A;  2OAZ A;  4U6E A;  4ZWP A;  5CIK A;  4PNC A;  4U6W A;  3PN9 A;  3CB6 A;  4S00 A;  3TAV A;  3MX6 A;  2ZSG A;  2Q92 A;  1R58 A;  3BIP A;  3PKA A;  4FLL A;  2V3Y A;  4U75 A;  1C22 A;  4RZY A;  2Q96 A;  2Q8K A;  4EGE A;  4FO7 A;  1YW9 A;  1XGS A;  1A16 A;  1C27 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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