4QR8A

Crystal structure of e coli pepq
Total Genus 149
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
149
sequence length
441
structure length
441
Chain Sequence
SLASLYKNHIATLQERTRDALARFKLDALLIHSGELFNVFLDDHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPTSFWTEDVEVIALPKADGIGSLLPAARGNIGYIGPVPERALQLGIEASNINPKGVIDYLHYYRSFKTEYELACMREAQKMAVNGHRAAEEAFRSGMSEFDINIAYLTATGHRDTDVPYSNIVALNEHAAVLHYTKLDHQAPEEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVKDVNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMPHGIGHPLGLQVHDVAGFMQDDSGTHLAAPAKYPYLRCTRILQPGMVLTIEPGIYFIESLLAPWREGQFSKHFNWQKIEALKPFGGIRIEDNVVIHENNVENMTRDLKLA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis of substrate selectivity of E. coli prolidase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Xaa-Pro dipeptidase
total genus 149
structure length 441
sequence length 441
chains with identical sequence B
ec nomenclature ec 3.4.13.9: Xaa-Pro dipeptidase.
pdb deposition date 2014-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 4qr8A01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 4qr8A02
1B6AA 1O0XA 3O5VA 4U69A 3TB5A 5JHUA 4S2TP 2GTXA 1QXZA 3OVKA 4RGZ1 3D27A 4IU6A 3MATA 2B3HA 1R5GA 4U6WA 3L24A 3Q6DA 2BWSA 3PKBA 1R5HA 1XGNA 1YW9A 3OOOA 4PV4A 1QXYA 2Q92A 3IU7A 1XNZA 2GGCA 2B3KA 3FMQA 3FM3A 5CLSA 4FLKA 1C23A 2GG2A 1XGSA 2BN7A 4Z7MA 2BWUA 2GG9A 4OOKA 5CNXA 1Y1NA 3CB5A 4FO8A 5FCFA 2GG5A 2GG7A 1WN1A 1KP0A 1WL9A 5CIKA 3BIQA 2Q94A 3FMRA 1CHMA 4IPAA 5CDLA 1C21A 4FLIA 3S6BA 2ADUA 3IL0A 4IKRA 2BWXA 4U71A 1W2MA 2NQ6A 3MR1A 2HOWA 4ZWPA 4IKUA 4A6VA 2BHDA 4ZWUA 3I7MA 4RZZA 4EGEA 5JFRA 1XGMA 5CDEA 2Q8KA 2ZSGA 2BWWA 4U76A 1A16A 1R58A 2BB7A 4S2RP 3IG4A 3PKCA 1KQ9A 5E5BA 1PV9A 4U6JA 3IU9A 1WL6A 1W7VA 2Q95A 2G6PA 2NQ7A 2OKNA 5D6EA 5E2CA 2GG3A 4RZYA 3PN9A 4U6EA 5CDVA 2V3ZA 3TAVA 4A6WA 1MATA 1M35A 2Q93A 4IKSA 2EA4A 2MATA 4S00A 4FKCA 2EVCA 4U70A 3QOCA 4ZWOA 1BOAA 2BH3A 2DFIA 2GGBA 2Q96A 4PNCA 4IF7A 1WKMA 1WLRA 3BIPA 3RORA 2EA2A 2V6CA 2GU6A 4KM3A 2BHBA 4B28A 4S01A 2B3LA 4U1BA 3L7GA 4U6ZA 2BWVA 3MX6A 1JAWA 3PKDA 2GU7A 3PEBA 2BHAA 5CE6A 4IKTA 1YW7A 2EVOA 1C27A 4FUKA 2IW2A 2OAZA 4QR8A 4FO7A 4IDYA 4ZNGA 3BITA 3PKAA 1WY2A 1C22A 4U6CA 4U73A 2BWTA 2GG0A 4U75A 1N51A 2P98A 3CB6A 3IU8A 2GG8A 2GU4A 3PKEA 3CTZA 1C24A 2EVMA 4HXXA 1QXWA 2P99A 5FCHA 4FLJA 2GA2A 2BHCA 2V3YA 2GZ5A 1XGOA 2P9AA 5JI6A 1BN5A 4IECA 1YW8A 1YVMA 4JUQA 1WBQA 2V3XA 4MATA 2GU5A 4FLLA 1QZYA 1B59A 1KQ0A 4R60A 3RVAA 5D6FA 1YJ3A 2BWYA
chains in the Genus database with same CATH superfamily
1B6AA 1O0XA 3O5VA 4U69A 3TB5A 5JHUA 4S2TP 2GTXA 1QXZA 3OVKA 4RGZ1 3D27A 4IU6A 3MATA 2B3HA 1R5GA 4U6WA 3L24A 3Q6DA 2BWSA 3PKBA 1R5HA 1XGNA 1YW9A 3OOOA 4PV4A 1QXYA 2Q92A 3IU7A 1XNZA 2GGCA 2B3KA 3FMQA 3FM3A 5CLSA 4FLKA 1C23A 2GG2A 1XGSA 2BN7A 4Z7MA 2BWUA 2GG9A 4OOKA 5CNXA 1Y1NA 3CB5A 4FO8A 5FCFA 2GG5A 2GG7A 1WN1A 1KP0A 1WL9A 5CIKA 3BIQA 2Q94A 3FMRA 1CHMA 4IPAA 5CDLA 1C21A 4FLIA 3S6BA 2ADUA 3IL0A 4IKRA 2BWXA 4U71A 1W2MA 2NQ6A 3MR1A 2HOWA 4ZWPA 4IKUA 4A6VA 2BHDA 4ZWUA 3I7MA 4RZZA 4EGEA 5JFRA 1XGMA 5CDEA 2Q8KA 2ZSGA 2BWWA 4U76A 1A16A 1R58A 2BB7A 4S2RP 3IG4A 3PKCA 1KQ9A 5E5BA 1PV9A 4U6JA 3IU9A 1WL6A 1W7VA 2Q95A 2G6PA 2NQ7A 2OKNA 5D6EA 5E2CA 2GG3A 4RZYA 3PN9A 4U6EA 5CDVA 2V3ZA 3TAVA 4A6WA 1MATA 1M35A 2Q93A 4IKSA 2EA4A 2MATA 4S00A 4FKCA 2EVCA 4U70A 3QOCA 4ZWOA 1BOAA 2BH3A 2DFIA 2GGBA 2Q96A 4PNCA 4IF7A 1WKMA 1WLRA 3BIPA 3RORA 2EA2A 2V6CA 2GU6A 4KM3A 2BHBA 4B28A 4S01A 2B3LA 4U1BA 3L7GA 4U6ZA 2BWVA 3MX6A 1JAWA 3PKDA 2GU7A 3PEBA 2BHAA 5CE6A 4IKTA 1YW7A 2EVOA 1C27A 4FUKA 2IW2A 2OAZA 4QR8A 4FO7A 4IDYA 4ZNGA 3BITA 3PKAA 1WY2A 1C22A 4U6CA 4U73A 2BWTA 2GG0A 4U75A 1N51A 2P98A 3CB6A 3IU8A 2GG8A 2GU4A 3PKEA 3CTZA 1C24A 2EVMA 4HXXA 1QXWA 2P99A 5FCHA 4FLJA 2GA2A 2BHCA 2V3YA 2GZ5A 1XGOA 2P9AA 5JI6A 1BN5A 4IECA 1YW8A 1YVMA 4JUQA 1WBQA 2V3XA 4MATA 2GU5A 4FLLA 1QZYA 1B59A 1KQ0A 4R60A 3RVAA 5D6FA 1YJ3A 2BWYA
chains in the Genus database with same CATH topology
1B6AA 1O0XA 3O5VA 4U69A 3TB5A 5JHUA 4S2TP 2GTXA 1QXZA 3OVKA 4RGZ1 3D27A 4IU6A 3MATA 2B3HA 1R5GA 4U6WA 3L24A 3Q6DA 2BWSA 3PKBA 1R5HA 1XGNA 1YW9A 3OOOA 4PV4A 1QXYA 2Q92A 3IU7A 1XNZA 2GGCA 2B3KA 3FMQA 3FM3A 5CLSA 4FLKA 1C23A 2GG2A 1XGSA 2BN7A 4Z7MA 2BWUA 2GG9A 4OOKA 5CNXA 1Y1NA 3CB5A 4FO8A 5FCFA 2GG5A 2GG7A 1WN1A 1KP0A 1WL9A 5CIKA 3BIQA 2Q94A 3FMRA 1CHMA 4IPAA 5CDLA 1C21A 4FLIA 3S6BA 2ADUA 3IL0A 4IKRA 2BWXA 4U71A 1W2MA 2NQ6A 3MR1A 2HOWA 4ZWPA 4IKUA 4A6VA 2BHDA 4ZWUA 3I7MA 4RZZA 4EGEA 5JFRA 1XGMA 5CDEA 2Q8KA 2ZSGA 2BWWA 4U76A 1A16A 1R58A 2BB7A 4S2RP 3IG4A 3PKCA 1KQ9A 5E5BA 1PV9A 4U6JA 3IU9A 1WL6A 1W7VA 2Q95A 2G6PA 2NQ7A 2OKNA 5D6EA 5E2CA 2GG3A 4RZYA 3PN9A 4U6EA 5CDVA 2V3ZA 3TAVA 4A6WA 1MATA 1M35A 2Q93A 4IKSA 2EA4A 2MATA 4S00A 4FKCA 2EVCA 4U70A 3QOCA 4ZWOA 1BOAA 2BH3A 2DFIA 2GGBA 2Q96A 4PNCA 4IF7A 1WKMA 1WLRA 3BIPA 3RORA 2EA2A 2V6CA 2GU6A 4KM3A 2BHBA 4B28A 4S01A 2B3LA 4U1BA 3L7GA 4U6ZA 2BWVA 3MX6A 1JAWA 3PKDA 2GU7A 3PEBA 2BHAA 5CE6A 4IKTA 1YW7A 2EVOA 1C27A 4FUKA 2IW2A 2OAZA 4QR8A 4FO7A 4IDYA 4ZNGA 3BITA 3PKAA 1WY2A 1C22A 4U6CA 4U73A 2BWTA 2GG0A 4U75A 1N51A 2P98A 3CB6A 3IU8A 2GG8A 2GU4A 3PKEA 3CTZA 1C24A 2EVMA 4HXXA 1QXWA 2P99A 5FCHA 4FLJA 2GA2A 2BHCA 2V3YA 2GZ5A 1XGOA 2P9AA 5JI6A 1BN5A 4IECA 1YW8A 1YVMA 4JUQA 1WBQA 2V3XA 4MATA 2GU5A 4FLLA 1QZYA 1B59A 1KQ0A 4R60A 3RVAA 5D6FA 1YJ3A 2BWYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1B6A A;  1O0X A;  3O5V A;  4U69 A;  3TB5 A;  5JHU A;  4S2T P;  2GTX A;  1QXZ A;  3OVK A;  4RGZ 1;  3D27 A;  4IU6 A;  3MAT A;  2B3H A;  1R5G A;  4U6W A;  3L24 A;  3Q6D A;  2BWS A;  3PKB A;  1R5H A;  1XGN A;  1YW9 A;  3OOO A;  4PV4 A;  1QXY A;  2Q92 A;  3IU7 A;  1XNZ A;  2GGC A;  2B3K A;  3FMQ A;  3FM3 A;  5CLS A;  4FLK A;  1C23 A;  2GG2 A;  1XGS A;  2BN7 A;  4Z7M A;  2BWU A;  2GG9 A;  4OOK A;  5CNX A;  1Y1N A;  3CB5 A;  4FO8 A;  5FCF A;  2GG5 A;  2GG7 A;  1WN1 A;  1KP0 A;  1WL9 A;  5CIK A;  3BIQ A;  2Q94 A;  3FMR A;  1CHM A;  4IPA A;  5CDL A;  1C21 A;  4FLI A;  3S6B A;  2ADU A;  3IL0 A;  4IKR A;  2BWX A;  4U71 A;  1W2M A;  2NQ6 A;  3MR1 A;  2HOW A;  4ZWP A;  4IKU A;  4A6V A;  2BHD A;  4ZWU A;  3I7M A;  4RZZ A;  4EGE A;  5JFR A;  1XGM A;  5CDE A;  2Q8K A;  2ZSG A;  2BWW A;  4U76 A;  1A16 A;  1R58 A;  2BB7 A;  4S2R P;  3IG4 A;  3PKC A;  1KQ9 A;  5E5B A;  1PV9 A;  4U6J A;  3IU9 A;  1WL6 A;  1W7V A;  2Q95 A;  2G6P A;  2NQ7 A;  2OKN A;  5D6E A;  5E2C A;  2GG3 A;  4RZY A;  3PN9 A;  4U6E A;  5CDV A;  2V3Z A;  3TAV A;  4A6W A;  1MAT A;  1M35 A;  2Q93 A;  4IKS A;  2EA4 A;  2MAT A;  4S00 A;  4FKC A;  2EVC A;  4U70 A;  3QOC A;  4ZWO A;  1BOA A;  2BH3 A;  2DFI A;  2GGB A;  2Q96 A;  4PNC A;  4IF7 A;  1WKM A;  1WLR A;  3BIP A;  3ROR A;  2EA2 A;  2V6C A;  2GU6 A;  4KM3 A;  2BHB A;  4B28 A;  4S01 A;  2B3L A;  4U1B A;  3L7G A;  4U6Z A;  2BWV A;  3MX6 A;  1JAW A;  3PKD A;  2GU7 A;  3PEB A;  2BHA A;  5CE6 A;  4IKT A;  1YW7 A;  2EVO A;  1C27 A;  4FUK A;  2IW2 A;  2OAZ A;  4QR8 A;  4FO7 A;  4IDY A;  4ZNG A;  3BIT A;  3PKA A;  1WY2 A;  1C22 A;  4U6C A;  4U73 A;  2BWT A;  2GG0 A;  4U75 A;  1N51 A;  2P98 A;  3CB6 A;  3IU8 A;  2GG8 A;  2GU4 A;  3PKE A;  3CTZ A;  1C24 A;  2EVM A;  4HXX A;  1QXW A;  2P99 A;  5FCH A;  4FLJ A;  2GA2 A;  2BHC A;  2V3Y A;  2GZ5 A;  1XGO A;  2P9A A;  5JI6 A;  1BN5 A;  4IEC A;  1YW8 A;  1YVM A;  4JUQ A;  1WBQ A;  2V3X A;  4MAT A;  2GU5 A;  4FLL A;  1QZY A;  1B59 A;  1KQ0 A;  4R60 A;  3RVA A;  5D6F A;  1YJ3 A;  2BWY A; 
#chains in the Genus database with same CATH topology
 1B6A A;  1O0X A;  3O5V A;  4U69 A;  3TB5 A;  5JHU A;  4S2T P;  2GTX A;  1QXZ A;  3OVK A;  4RGZ 1;  3D27 A;  4IU6 A;  3MAT A;  2B3H A;  1R5G A;  4U6W A;  3L24 A;  3Q6D A;  2BWS A;  3PKB A;  1R5H A;  1XGN A;  1YW9 A;  3OOO A;  4PV4 A;  1QXY A;  2Q92 A;  3IU7 A;  1XNZ A;  2GGC A;  2B3K A;  3FMQ A;  3FM3 A;  5CLS A;  4FLK A;  1C23 A;  2GG2 A;  1XGS A;  2BN7 A;  4Z7M A;  2BWU A;  2GG9 A;  4OOK A;  5CNX A;  1Y1N A;  3CB5 A;  4FO8 A;  5FCF A;  2GG5 A;  2GG7 A;  1WN1 A;  1KP0 A;  1WL9 A;  5CIK A;  3BIQ A;  2Q94 A;  3FMR A;  1CHM A;  4IPA A;  5CDL A;  1C21 A;  4FLI A;  3S6B A;  2ADU A;  3IL0 A;  4IKR A;  2BWX A;  4U71 A;  1W2M A;  2NQ6 A;  3MR1 A;  2HOW A;  4ZWP A;  4IKU A;  4A6V A;  2BHD A;  4ZWU A;  3I7M A;  4RZZ A;  4EGE A;  5JFR A;  1XGM A;  5CDE A;  2Q8K A;  2ZSG A;  2BWW A;  4U76 A;  1A16 A;  1R58 A;  2BB7 A;  4S2R P;  3IG4 A;  3PKC A;  1KQ9 A;  5E5B A;  1PV9 A;  4U6J A;  3IU9 A;  1WL6 A;  1W7V A;  2Q95 A;  2G6P A;  2NQ7 A;  2OKN A;  5D6E A;  5E2C A;  2GG3 A;  4RZY A;  3PN9 A;  4U6E A;  5CDV A;  2V3Z A;  3TAV A;  4A6W A;  1MAT A;  1M35 A;  2Q93 A;  4IKS A;  2EA4 A;  2MAT A;  4S00 A;  4FKC A;  2EVC A;  4U70 A;  3QOC A;  4ZWO A;  1BOA A;  2BH3 A;  2DFI A;  2GGB A;  2Q96 A;  4PNC A;  4IF7 A;  1WKM A;  1WLR A;  3BIP A;  3ROR A;  2EA2 A;  2V6C A;  2GU6 A;  4KM3 A;  2BHB A;  4B28 A;  4S01 A;  2B3L A;  4U1B A;  3L7G A;  4U6Z A;  2BWV A;  3MX6 A;  1JAW A;  3PKD A;  2GU7 A;  3PEB A;  2BHA A;  5CE6 A;  4IKT A;  1YW7 A;  2EVO A;  1C27 A;  4FUK A;  2IW2 A;  2OAZ A;  4QR8 A;  4FO7 A;  4IDY A;  4ZNG A;  3BIT A;  3PKA A;  1WY2 A;  1C22 A;  4U6C A;  4U73 A;  2BWT A;  2GG0 A;  4U75 A;  1N51 A;  2P98 A;  3CB6 A;  3IU8 A;  2GG8 A;  2GU4 A;  3PKE A;  3CTZ A;  1C24 A;  2EVM A;  4HXX A;  1QXW A;  2P99 A;  5FCH A;  4FLJ A;  2GA2 A;  2BHC A;  2V3Y A;  2GZ5 A;  1XGO A;  2P9A A;  5JI6 A;  1BN5 A;  4IEC A;  1YW8 A;  1YVM A;  4JUQ A;  1WBQ A;  2V3X A;  4MAT A;  2GU5 A;  4FLL A;  1QZY A;  1B59 A;  1KQ0 A;  4R60 A;  3RVA A;  5D6F A;  1YJ3 A;  2BWY A; 
#chains in the Genus database with same CATH homology
 1B6A A;  1O0X A;  3O5V A;  4U69 A;  3TB5 A;  5JHU A;  4S2T P;  2GTX A;  1QXZ A;  3OVK A;  4RGZ 1;  3D27 A;  4IU6 A;  3MAT A;  2B3H A;  1R5G A;  4U6W A;  3L24 A;  3Q6D A;  2BWS A;  3PKB A;  1R5H A;  1XGN A;  1YW9 A;  3OOO A;  4PV4 A;  1QXY A;  2Q92 A;  3IU7 A;  1XNZ A;  2GGC A;  2B3K A;  3FMQ A;  3FM3 A;  5CLS A;  4FLK A;  1C23 A;  2GG2 A;  1XGS A;  2BN7 A;  4Z7M A;  2BWU A;  2GG9 A;  4OOK A;  5CNX A;  1Y1N A;  3CB5 A;  4FO8 A;  5FCF A;  2GG5 A;  2GG7 A;  1WN1 A;  1KP0 A;  1WL9 A;  5CIK A;  3BIQ A;  2Q94 A;  3FMR A;  1CHM A;  4IPA A;  5CDL A;  1C21 A;  4FLI A;  3S6B A;  2ADU A;  3IL0 A;  4IKR A;  2BWX A;  4U71 A;  1W2M A;  2NQ6 A;  3MR1 A;  2HOW A;  4ZWP A;  4IKU A;  4A6V A;  2BHD A;  4ZWU A;  3I7M A;  4RZZ A;  4EGE A;  5JFR A;  1XGM A;  5CDE A;  2Q8K A;  2ZSG A;  2BWW A;  4U76 A;  1A16 A;  1R58 A;  2BB7 A;  4S2R P;  3IG4 A;  3PKC A;  1KQ9 A;  5E5B A;  1PV9 A;  4U6J A;  3IU9 A;  1WL6 A;  1W7V A;  2Q95 A;  2G6P A;  2NQ7 A;  2OKN A;  5D6E A;  5E2C A;  2GG3 A;  4RZY A;  3PN9 A;  4U6E A;  5CDV A;  2V3Z A;  3TAV A;  4A6W A;  1MAT A;  1M35 A;  2Q93 A;  4IKS A;  2EA4 A;  2MAT A;  4S00 A;  4FKC A;  2EVC A;  4U70 A;  3QOC A;  4ZWO A;  1BOA A;  2BH3 A;  2DFI A;  2GGB A;  2Q96 A;  4PNC A;  4IF7 A;  1WKM A;  1WLR A;  3BIP A;  3ROR A;  2EA2 A;  2V6C A;  2GU6 A;  4KM3 A;  2BHB A;  4B28 A;  4S01 A;  2B3L A;  4U1B A;  3L7G A;  4U6Z A;  2BWV A;  3MX6 A;  1JAW A;  3PKD A;  2GU7 A;  3PEB A;  2BHA A;  5CE6 A;  4IKT A;  1YW7 A;  2EVO A;  1C27 A;  4FUK A;  2IW2 A;  2OAZ A;  4QR8 A;  4FO7 A;  4IDY A;  4ZNG A;  3BIT A;  3PKA A;  1WY2 A;  1C22 A;  4U6C A;  4U73 A;  2BWT A;  2GG0 A;  4U75 A;  1N51 A;  2P98 A;  3CB6 A;  3IU8 A;  2GG8 A;  2GU4 A;  3PKE A;  3CTZ A;  1C24 A;  2EVM A;  4HXX A;  1QXW A;  2P99 A;  5FCH A;  4FLJ A;  2GA2 A;  2BHC A;  2V3Y A;  2GZ5 A;  1XGO A;  2P9A A;  5JI6 A;  1BN5 A;  4IEC A;  1YW8 A;  1YVM A;  4JUQ A;  1WBQ A;  2V3X A;  4MAT A;  2GU5 A;  4FLL A;  1QZY A;  1B59 A;  1KQ0 A;  4R60 A;  3RVA A;  5D6F A;  1YJ3 A;  2BWY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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