5E5BA

Crystal structure of human spt16 n-terminal domain
Total Genus 150
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
150
sequence length
431
structure length
431
Chain Sequence
AVTLDKDAYYRRVKRLYSNWRKGEDEYANVDAIVVSVGVDEEIVYAKSTALQTWLFGYELTDTIMVFCDDKIIFMASKKKVEFLKQIANTKGNENANGAPAITLLIREKNESNKSSFDKMIEAIKESKNGKKIGVFSKDKFPGEFMKSWNDCLNKEGFDKIDISAVVAYTIAVKEDGELNLMKKAASITSEVFNKFFKERVMEIVDADEKVRHSKLAESVEKAIEEKKYLAGADPSTVEMCYPPIIQSGGNYNLKFSVVSDKNHMHFGAITCAMGIRFKSYCSNLVRTLMVDPSQEVQENYNFLLQLQEELLKELRHGVKICDVYNAVMDVVKKQKPELLNKITKNLGFGMGIEFREGSLVINSKNQYKLKKGMVFSINLGFSDLTNKEGKKPEEKTYALFIGDTVLVDEDGPATVLTSVKKKVKNVGIFL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the human histone chaperone FACT Spt16 N-terminal domain.
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords FACT complex subunit SPT16
total genus 150
structure length 431
sequence length 431
ec nomenclature
pdb deposition date 2015-10-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF14826 FACT-Spt16_Nlob FACT complex subunit SPT16 N-terminal lobe domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 5e5bA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 5e5bA02
1JAWA 3BIPA 4QR8A 4S2TP 4ZNGA 4ZWUA 2GU5A 3FMRA 3CB5A 2OAZA 5FCHA 2GU7A 3IU7A 4EGEA 2B3KA 4S2RP 4U1BA 1WBQA 1QXYA 1R5HA 4U75A 1YJ3A 3CTZA 3I7MA 2GGBA 1C24A 3BIQA 3CB6A 1C23A 1KQ9A 5E5BA 3MX6A 3PKEA 4RZYA 4KM3A 3RVAA 2Q96A 2MATA 1B59A 5JHUA 2ADUA 5E2CA 4A6VA 1Y1NA 1MATA 5CDVA 4IKSA 1WL6A 1YVMA 3L7GA 3PN9A 1CHMA 4U6WA 1YW7A 2Q92A 4IKTA 4PNCA 1WL9A 1XGSA 3FM3A 2GG5A 2GA2A 3D27A 2BHBA 2BWVA 1QXZA 3IG4A 2EVOA 4FLKA 3RORA 4RGZ1 5CDLA 3PKDA 2BWWA 3BITA 1XNZA 4IKUA 4U71A 2GZ5A 4U73A 1KQ0A 2GG3A 4FLIA 2P9AA 2Q8KA 2V3YA 1C21A 1A16A 1YW8A 3L24A 5CIKA 2BWUA 2BN7A 2GG9A 1XGMA 2P98A 2HOWA 1QXWA 4FKCA 2NQ6A 5JFRA 3IL0A 2BWSA 3FMQA 2V3XA 5CNXA 1PV9A 2BHCA 1WKMA 5JI6A 2IW2A 4IECA 1WN1A 2V3ZA 4U6ZA 2G6PA 4S01A 1XGOA 4U76A 3O5VA 1R58A 2DFIA 2NQ7A 3QOCA 1C22A 5CLSA 4U6JA 2EVMA 2EA2A 4Z7MA 1KP0A 1BOAA 4FLJA 4U6EA 1BN5A 2BWTA 2EVCA 3MATA 3OOOA 4FO7A 4S00A 3PKAA 4FO8A 4R60A 1C27A 4B28A 4A6WA 2EA4A 2B3LA 1WY2A 3Q6DA 2BWYA 3S6BA 1M35A 2GG8A 2GU6A 2GU4A 3IU8A 4U6CA 5FCFA 4IKRA 4MATA 2P99A 1QZYA 4JUQA 5CE6A 4RZZA 3PEBA 2BWXA 2GG7A 5D6FA 2B3HA 4IF7A 1YW9A 1W7VA 5CDEA 2ZSGA 3TB5A 2V6CA 2Q93A 4PV4A 1N51A 1R5GA 4IPAA 4IU6A 2OKNA 2GGCA 3OVKA 2BHAA 2Q95A 4FLLA 1B6AA 5D6EA 3IU9A 1WLRA 2GG0A 4ZWOA 2BB7A 4ZWPA 3PKBA 4HXXA 4FUKA 2GG2A 3MR1A 4U69A 3TAVA 1W2MA 3PKCA 1O0XA 1XGNA 2Q94A 4U70A 2BH3A 2GTXA 2BHDA 4OOKA 4IDYA
chains in the Genus database with same CATH superfamily
1JAWA 3BIPA 4QR8A 4S2TP 4ZNGA 4ZWUA 2GU5A 3FMRA 3CB5A 2OAZA 5FCHA 2GU7A 3IU7A 4EGEA 2B3KA 4S2RP 4U1BA 1WBQA 1QXYA 1R5HA 4U75A 1YJ3A 3CTZA 3I7MA 2GGBA 1C24A 3BIQA 3CB6A 1C23A 1KQ9A 5E5BA 3MX6A 3PKEA 4RZYA 4KM3A 3RVAA 2Q96A 2MATA 1B59A 5JHUA 2ADUA 5E2CA 4A6VA 1Y1NA 1MATA 5CDVA 4IKSA 1WL6A 1YVMA 3L7GA 3PN9A 1CHMA 4U6WA 1YW7A 2Q92A 4IKTA 4PNCA 1WL9A 1XGSA 3FM3A 2GG5A 2GA2A 3D27A 2BHBA 2BWVA 1QXZA 3IG4A 2EVOA 4FLKA 3RORA 4RGZ1 5CDLA 3PKDA 2BWWA 3BITA 1XNZA 4IKUA 4U71A 2GZ5A 4U73A 1KQ0A 2GG3A 4FLIA 2P9AA 2Q8KA 2V3YA 1C21A 1A16A 1YW8A 3L24A 5CIKA 2BWUA 2BN7A 2GG9A 1XGMA 2P98A 2HOWA 1QXWA 4FKCA 2NQ6A 5JFRA 3IL0A 2BWSA 3FMQA 2V3XA 5CNXA 1PV9A 2BHCA 1WKMA 5JI6A 2IW2A 4IECA 1WN1A 2V3ZA 4U6ZA 2G6PA 4S01A 1XGOA 4U76A 3O5VA 1R58A 2DFIA 2NQ7A 3QOCA 1C22A 5CLSA 4U6JA 2EVMA 2EA2A 4Z7MA 1KP0A 1BOAA 4FLJA 4U6EA 1BN5A 2BWTA 2EVCA 3MATA 3OOOA 4FO7A 4S00A 3PKAA 4FO8A 4R60A 1C27A 4B28A 4A6WA 2EA4A 2B3LA 1WY2A 3Q6DA 2BWYA 3S6BA 1M35A 2GG8A 2GU6A 2GU4A 3IU8A 4U6CA 5FCFA 4IKRA 4MATA 2P99A 1QZYA 4JUQA 5CE6A 4RZZA 3PEBA 2BWXA 2GG7A 5D6FA 2B3HA 4IF7A 1YW9A 1W7VA 5CDEA 2ZSGA 3TB5A 2V6CA 2Q93A 4PV4A 1N51A 1R5GA 4IPAA 4IU6A 2OKNA 2GGCA 3OVKA 2BHAA 2Q95A 4FLLA 1B6AA 5D6EA 3IU9A 1WLRA 2GG0A 4ZWOA 2BB7A 4ZWPA 3PKBA 4HXXA 4FUKA 2GG2A 3MR1A 4U69A 3TAVA 1W2MA 3PKCA 1O0XA 1XGNA 2Q94A 4U70A 2BH3A 2GTXA 2BHDA 4OOKA 4IDYA
chains in the Genus database with same CATH topology
1JAWA 3BIPA 4QR8A 4S2TP 4ZNGA 4ZWUA 2GU5A 3FMRA 3CB5A 2OAZA 5FCHA 2GU7A 3IU7A 4EGEA 2B3KA 4S2RP 4U1BA 1WBQA 1QXYA 1R5HA 4U75A 1YJ3A 3CTZA 3I7MA 2GGBA 1C24A 3BIQA 3CB6A 1C23A 1KQ9A 5E5BA 3MX6A 3PKEA 4RZYA 4KM3A 3RVAA 2Q96A 2MATA 1B59A 5JHUA 2ADUA 5E2CA 4A6VA 1Y1NA 1MATA 5CDVA 4IKSA 1WL6A 1YVMA 3L7GA 3PN9A 1CHMA 4U6WA 1YW7A 2Q92A 4IKTA 4PNCA 1WL9A 1XGSA 3FM3A 2GG5A 2GA2A 3D27A 2BHBA 2BWVA 1QXZA 3IG4A 2EVOA 4FLKA 3RORA 4RGZ1 5CDLA 3PKDA 2BWWA 3BITA 1XNZA 4IKUA 4U71A 2GZ5A 4U73A 1KQ0A 2GG3A 4FLIA 2P9AA 2Q8KA 2V3YA 1C21A 1A16A 1YW8A 3L24A 5CIKA 2BWUA 2BN7A 2GG9A 1XGMA 2P98A 2HOWA 1QXWA 4FKCA 2NQ6A 5JFRA 3IL0A 2BWSA 3FMQA 2V3XA 5CNXA 1PV9A 2BHCA 1WKMA 5JI6A 2IW2A 4IECA 1WN1A 2V3ZA 4U6ZA 2G6PA 4S01A 1XGOA 4U76A 3O5VA 1R58A 2DFIA 2NQ7A 3QOCA 1C22A 5CLSA 4U6JA 2EVMA 2EA2A 4Z7MA 1KP0A 1BOAA 4FLJA 4U6EA 1BN5A 2BWTA 2EVCA 3MATA 3OOOA 4FO7A 4S00A 3PKAA 4FO8A 4R60A 1C27A 4B28A 4A6WA 2EA4A 2B3LA 1WY2A 3Q6DA 2BWYA 3S6BA 1M35A 2GG8A 2GU6A 2GU4A 3IU8A 4U6CA 5FCFA 4IKRA 4MATA 2P99A 1QZYA 4JUQA 5CE6A 4RZZA 3PEBA 2BWXA 2GG7A 5D6FA 2B3HA 4IF7A 1YW9A 1W7VA 5CDEA 2ZSGA 3TB5A 2V6CA 2Q93A 4PV4A 1N51A 1R5GA 4IPAA 4IU6A 2OKNA 2GGCA 3OVKA 2BHAA 2Q95A 4FLLA 1B6AA 5D6EA 3IU9A 1WLRA 2GG0A 4ZWOA 2BB7A 4ZWPA 3PKBA 4HXXA 4FUKA 2GG2A 3MR1A 4U69A 3TAVA 1W2MA 3PKCA 1O0XA 1XGNA 2Q94A 4U70A 2BH3A 2GTXA 2BHDA 4OOKA 4IDYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JAW A;  3BIP A;  4QR8 A;  4S2T P;  4ZNG A;  4ZWU A;  2GU5 A;  3FMR A;  3CB5 A;  2OAZ A;  5FCH A;  2GU7 A;  3IU7 A;  4EGE A;  2B3K A;  4S2R P;  4U1B A;  1WBQ A;  1QXY A;  1R5H A;  4U75 A;  1YJ3 A;  3CTZ A;  3I7M A;  2GGB A;  1C24 A;  3BIQ A;  3CB6 A;  1C23 A;  1KQ9 A;  5E5B A;  3MX6 A;  3PKE A;  4RZY A;  4KM3 A;  3RVA A;  2Q96 A;  2MAT A;  1B59 A;  5JHU A;  2ADU A;  5E2C A;  4A6V A;  1Y1N A;  1MAT A;  5CDV A;  4IKS A;  1WL6 A;  1YVM A;  3L7G A;  3PN9 A;  1CHM A;  4U6W A;  1YW7 A;  2Q92 A;  4IKT A;  4PNC A;  1WL9 A;  1XGS A;  3FM3 A;  2GG5 A;  2GA2 A;  3D27 A;  2BHB A;  2BWV A;  1QXZ A;  3IG4 A;  2EVO A;  4FLK A;  3ROR A;  4RGZ 1;  5CDL A;  3PKD A;  2BWW A;  3BIT A;  1XNZ A;  4IKU A;  4U71 A;  2GZ5 A;  4U73 A;  1KQ0 A;  2GG3 A;  4FLI A;  2P9A A;  2Q8K A;  2V3Y A;  1C21 A;  1A16 A;  1YW8 A;  3L24 A;  5CIK A;  2BWU A;  2BN7 A;  2GG9 A;  1XGM A;  2P98 A;  2HOW A;  1QXW A;  4FKC A;  2NQ6 A;  5JFR A;  3IL0 A;  2BWS A;  3FMQ A;  2V3X A;  5CNX A;  1PV9 A;  2BHC A;  1WKM A;  5JI6 A;  2IW2 A;  4IEC A;  1WN1 A;  2V3Z A;  4U6Z A;  2G6P A;  4S01 A;  1XGO A;  4U76 A;  3O5V A;  1R58 A;  2DFI A;  2NQ7 A;  3QOC A;  1C22 A;  5CLS A;  4U6J A;  2EVM A;  2EA2 A;  4Z7M A;  1KP0 A;  1BOA A;  4FLJ A;  4U6E A;  1BN5 A;  2BWT A;  2EVC A;  3MAT A;  3OOO A;  4FO7 A;  4S00 A;  3PKA A;  4FO8 A;  4R60 A;  1C27 A;  4B28 A;  4A6W A;  2EA4 A;  2B3L A;  1WY2 A;  3Q6D A;  2BWY A;  3S6B A;  1M35 A;  2GG8 A;  2GU6 A;  2GU4 A;  3IU8 A;  4U6C A;  5FCF A;  4IKR A;  4MAT A;  2P99 A;  1QZY A;  4JUQ A;  5CE6 A;  4RZZ A;  3PEB A;  2BWX A;  2GG7 A;  5D6F A;  2B3H A;  4IF7 A;  1YW9 A;  1W7V A;  5CDE A;  2ZSG A;  3TB5 A;  2V6C A;  2Q93 A;  4PV4 A;  1N51 A;  1R5G A;  4IPA A;  4IU6 A;  2OKN A;  2GGC A;  3OVK A;  2BHA A;  2Q95 A;  4FLL A;  1B6A A;  5D6E A;  3IU9 A;  1WLR A;  2GG0 A;  4ZWO A;  2BB7 A;  4ZWP A;  3PKB A;  4HXX A;  4FUK A;  2GG2 A;  3MR1 A;  4U69 A;  3TAV A;  1W2M A;  3PKC A;  1O0X A;  1XGN A;  2Q94 A;  4U70 A;  2BH3 A;  2GTX A;  2BHD A;  4OOK A;  4IDY A; 
#chains in the Genus database with same CATH topology
 1JAW A;  3BIP A;  4QR8 A;  4S2T P;  4ZNG A;  4ZWU A;  2GU5 A;  3FMR A;  3CB5 A;  2OAZ A;  5FCH A;  2GU7 A;  3IU7 A;  4EGE A;  2B3K A;  4S2R P;  4U1B A;  1WBQ A;  1QXY A;  1R5H A;  4U75 A;  1YJ3 A;  3CTZ A;  3I7M A;  2GGB A;  1C24 A;  3BIQ A;  3CB6 A;  1C23 A;  1KQ9 A;  5E5B A;  3MX6 A;  3PKE A;  4RZY A;  4KM3 A;  3RVA A;  2Q96 A;  2MAT A;  1B59 A;  5JHU A;  2ADU A;  5E2C A;  4A6V A;  1Y1N A;  1MAT A;  5CDV A;  4IKS A;  1WL6 A;  1YVM A;  3L7G A;  3PN9 A;  1CHM A;  4U6W A;  1YW7 A;  2Q92 A;  4IKT A;  4PNC A;  1WL9 A;  1XGS A;  3FM3 A;  2GG5 A;  2GA2 A;  3D27 A;  2BHB A;  2BWV A;  1QXZ A;  3IG4 A;  2EVO A;  4FLK A;  3ROR A;  4RGZ 1;  5CDL A;  3PKD A;  2BWW A;  3BIT A;  1XNZ A;  4IKU A;  4U71 A;  2GZ5 A;  4U73 A;  1KQ0 A;  2GG3 A;  4FLI A;  2P9A A;  2Q8K A;  2V3Y A;  1C21 A;  1A16 A;  1YW8 A;  3L24 A;  5CIK A;  2BWU A;  2BN7 A;  2GG9 A;  1XGM A;  2P98 A;  2HOW A;  1QXW A;  4FKC A;  2NQ6 A;  5JFR A;  3IL0 A;  2BWS A;  3FMQ A;  2V3X A;  5CNX A;  1PV9 A;  2BHC A;  1WKM A;  5JI6 A;  2IW2 A;  4IEC A;  1WN1 A;  2V3Z A;  4U6Z A;  2G6P A;  4S01 A;  1XGO A;  4U76 A;  3O5V A;  1R58 A;  2DFI A;  2NQ7 A;  3QOC A;  1C22 A;  5CLS A;  4U6J A;  2EVM A;  2EA2 A;  4Z7M A;  1KP0 A;  1BOA A;  4FLJ A;  4U6E A;  1BN5 A;  2BWT A;  2EVC A;  3MAT A;  3OOO A;  4FO7 A;  4S00 A;  3PKA A;  4FO8 A;  4R60 A;  1C27 A;  4B28 A;  4A6W A;  2EA4 A;  2B3L A;  1WY2 A;  3Q6D A;  2BWY A;  3S6B A;  1M35 A;  2GG8 A;  2GU6 A;  2GU4 A;  3IU8 A;  4U6C A;  5FCF A;  4IKR A;  4MAT A;  2P99 A;  1QZY A;  4JUQ A;  5CE6 A;  4RZZ A;  3PEB A;  2BWX A;  2GG7 A;  5D6F A;  2B3H A;  4IF7 A;  1YW9 A;  1W7V A;  5CDE A;  2ZSG A;  3TB5 A;  2V6C A;  2Q93 A;  4PV4 A;  1N51 A;  1R5G A;  4IPA A;  4IU6 A;  2OKN A;  2GGC A;  3OVK A;  2BHA A;  2Q95 A;  4FLL A;  1B6A A;  5D6E A;  3IU9 A;  1WLR A;  2GG0 A;  4ZWO A;  2BB7 A;  4ZWP A;  3PKB A;  4HXX A;  4FUK A;  2GG2 A;  3MR1 A;  4U69 A;  3TAV A;  1W2M A;  3PKC A;  1O0X A;  1XGN A;  2Q94 A;  4U70 A;  2BH3 A;  2GTX A;  2BHD A;  4OOK A;  4IDY A; 
#chains in the Genus database with same CATH homology
 1JAW A;  3BIP A;  4QR8 A;  4S2T P;  4ZNG A;  4ZWU A;  2GU5 A;  3FMR A;  3CB5 A;  2OAZ A;  5FCH A;  2GU7 A;  3IU7 A;  4EGE A;  2B3K A;  4S2R P;  4U1B A;  1WBQ A;  1QXY A;  1R5H A;  4U75 A;  1YJ3 A;  3CTZ A;  3I7M A;  2GGB A;  1C24 A;  3BIQ A;  3CB6 A;  1C23 A;  1KQ9 A;  5E5B A;  3MX6 A;  3PKE A;  4RZY A;  4KM3 A;  3RVA A;  2Q96 A;  2MAT A;  1B59 A;  5JHU A;  2ADU A;  5E2C A;  4A6V A;  1Y1N A;  1MAT A;  5CDV A;  4IKS A;  1WL6 A;  1YVM A;  3L7G A;  3PN9 A;  1CHM A;  4U6W A;  1YW7 A;  2Q92 A;  4IKT A;  4PNC A;  1WL9 A;  1XGS A;  3FM3 A;  2GG5 A;  2GA2 A;  3D27 A;  2BHB A;  2BWV A;  1QXZ A;  3IG4 A;  2EVO A;  4FLK A;  3ROR A;  4RGZ 1;  5CDL A;  3PKD A;  2BWW A;  3BIT A;  1XNZ A;  4IKU A;  4U71 A;  2GZ5 A;  4U73 A;  1KQ0 A;  2GG3 A;  4FLI A;  2P9A A;  2Q8K A;  2V3Y A;  1C21 A;  1A16 A;  1YW8 A;  3L24 A;  5CIK A;  2BWU A;  2BN7 A;  2GG9 A;  1XGM A;  2P98 A;  2HOW A;  1QXW A;  4FKC A;  2NQ6 A;  5JFR A;  3IL0 A;  2BWS A;  3FMQ A;  2V3X A;  5CNX A;  1PV9 A;  2BHC A;  1WKM A;  5JI6 A;  2IW2 A;  4IEC A;  1WN1 A;  2V3Z A;  4U6Z A;  2G6P A;  4S01 A;  1XGO A;  4U76 A;  3O5V A;  1R58 A;  2DFI A;  2NQ7 A;  3QOC A;  1C22 A;  5CLS A;  4U6J A;  2EVM A;  2EA2 A;  4Z7M A;  1KP0 A;  1BOA A;  4FLJ A;  4U6E A;  1BN5 A;  2BWT A;  2EVC A;  3MAT A;  3OOO A;  4FO7 A;  4S00 A;  3PKA A;  4FO8 A;  4R60 A;  1C27 A;  4B28 A;  4A6W A;  2EA4 A;  2B3L A;  1WY2 A;  3Q6D A;  2BWY A;  3S6B A;  1M35 A;  2GG8 A;  2GU6 A;  2GU4 A;  3IU8 A;  4U6C A;  5FCF A;  4IKR A;  4MAT A;  2P99 A;  1QZY A;  4JUQ A;  5CE6 A;  4RZZ A;  3PEB A;  2BWX A;  2GG7 A;  5D6F A;  2B3H A;  4IF7 A;  1YW9 A;  1W7V A;  5CDE A;  2ZSG A;  3TB5 A;  2V6C A;  2Q93 A;  4PV4 A;  1N51 A;  1R5G A;  4IPA A;  4IU6 A;  2OKN A;  2GGC A;  3OVK A;  2BHA A;  2Q95 A;  4FLL A;  1B6A A;  5D6E A;  3IU9 A;  1WLR A;  2GG0 A;  4ZWO A;  2BB7 A;  4ZWP A;  3PKB A;  4HXX A;  4FUK A;  2GG2 A;  3MR1 A;  4U69 A;  3TAV A;  1W2M A;  3PKC A;  1O0X A;  1XGN A;  2Q94 A;  4U70 A;  2BH3 A;  2GTX A;  2BHD A;  4OOK A;  4IDY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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