5FCHA

Crystal structure of xaa-pro dipeptidase from xanthomonas campestris, phosphate and zn bound
Total Genus 133
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
133
sequence length
398
structure length
398
Chain Sequence
STQIGGMSLDQARTQLAPWTQRAAPIGADEYQQRIERARVLMRAQGVDALLIGAGTSLRYFSGVPWGASERLVALLLTTEGDPVLICPAFEEGSLDAVLQLPVRKRLWEEHEDPYALVVQAMDEQHAHALALDPGIAFAVHTGLRAHLGTAIRDAGAIIDGCRMCKSPAELALMQQACDMTLLVQRLAAGIAHEGIGTDQLVRFIDEAHRALGADNGSTFCIVQFGHATAFPHGIPGVQHLRAGELVLIDTGCTVQGYHSDITRTWIYGTPSDAQQRIWELELAAQAAAFAAVRPGVACEAVDQAARAVLQAAGLGPDYRLPGLPHRTGHGCGLAIHEAPYLVRGNRQPLQPGMCASNEPMIVVPGAFGVRLEDHFYVTDTGAQWFTPPSVAIDQPFA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure and biochemical investigations reveal novel mode of substrate selectivity and illuminate substrate inhibition and allostericity in a subfamily of Xaa-Pro dipeptidases
pubmed doi rcsb
source organism Xanthomonas campestris pv. campestris str. atcc 33913
molecule tags Hydrolase
molecule keywords Proline dipeptidase
total genus 133
structure length 398
sequence length 398
chains with identical sequence B
ec nomenclature ec 3.4.13.9: Xaa-Pro dipeptidase.
pdb deposition date 2015-12-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 5fchA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 5fchA02
2OKNA 2Q95A 2HOWA 1KP0A 2GG9A 2BWXA 3O5VA 5CNXA 2P99A 1C24A 5CDVA 4IKUA 3L24A 1R5HA 4KM3A 3MX6A 1Y1NA 4FLJA 1W2MA 1R58A 2GGBA 2GZ5A 2BWTA 3Q6DA 2BB7A 2EA2A 4U70A 5D6EA 4IKSA 2ZSGA 4IECA 3PN9A 5FCFA 3IU7A 4ZNGA 1QXZA 2B3KA 4U75A 1XNZA 2IW2A 5CDEA 1R5GA 2BWYA 1KQ0A 2GTXA 4R60A 2GU6A 1XGOA 4IF7A 3PKBA 4JUQA 4ZWPA 2GG5A 4FKCA 2NQ6A 1B59A 1XGMA 1PV9A 2BN7A 1XGNA 5E5BA 2B3LA 1C22A 3PEBA 3BIQA 1JAWA 3BITA 2GA2A 5FCHA 5JHUA 2Q96A 4IPAA 1MATA 4U6CA 4U6JA 4S00A 2GG7A 1YVMA 3FM3A 1BN5A 3I7MA 2GU4A 3IU9A 4QR8A 3RORA 4FLIA 1WLRA 5E2CA 3TAVA 2V6CA 2EVMA 2GG3A 5D6FA 5CDLA 4IKTA 4RGZ1 1QXYA 2G6PA 4U6ZA 1WBQA 3QOCA 4IDYA 4RZYA 2Q92A 4IU6A 1WKMA 2Q8KA 1M35A 1WY2A 1CHMA 2P9AA 5JFRA 2NQ7A 2P98A 4FO8A 4FUKA 4FLKA 1WL9A 4EGEA 4RZZA 2DFIA 3OOOA 2OAZA 4ZWUA 1YW8A 2GG8A 1BOAA 3TB5A 2BWUA 2BHCA 3IG4A 2BWVA 4S2TP 3CB6A 1XGSA 2Q93A 4OOKA 4U76A 4A6VA 2BHDA 2GU7A 2GU5A 4B28A 1YW7A 1A16A 4S01A 4A6WA 3PKAA 1C21A 1KQ9A 2GG2A 2GGCA 5CIKA 2B3HA 2V3XA 1B6AA 4PV4A 4PNCA 4U1BA 1WL6A 3FMQA 4FO7A 3FMRA 2Q94A 2BWSA 3IU8A 4FLLA 3IL0A 2GG0A 3MR1A 1QZYA 4Z7MA 2BWWA 2EVOA 3S6BA 3BIPA 3L7GA 2BH3A 1N51A 1YW9A 4ZWOA 2EA4A 4U6WA 5JI6A 4S2RP 5CLSA 1WN1A 2V3YA 4IKRA 1C27A 3OVKA 3PKCA 3RVAA 5CE6A 1C23A 2BHAA 1QXWA 3CTZA 2EVCA 4MATA 2ADUA 1O0XA 4U73A 3PKEA 1YJ3A 4U71A 1W7VA 3D27A 4U69A 3MATA 3CB5A 2V3ZA 2BHBA 3PKDA 4HXXA 2MATA 4U6EA
chains in the Genus database with same CATH superfamily
2OKNA 2Q95A 2HOWA 1KP0A 2GG9A 2BWXA 3O5VA 5CNXA 2P99A 1C24A 5CDVA 4IKUA 3L24A 1R5HA 4KM3A 3MX6A 1Y1NA 4FLJA 1W2MA 1R58A 2GGBA 2GZ5A 2BWTA 3Q6DA 2BB7A 2EA2A 4U70A 5D6EA 4IKSA 2ZSGA 4IECA 3PN9A 5FCFA 3IU7A 4ZNGA 1QXZA 2B3KA 4U75A 1XNZA 2IW2A 5CDEA 1R5GA 2BWYA 1KQ0A 2GTXA 4R60A 2GU6A 1XGOA 4IF7A 3PKBA 4JUQA 4ZWPA 2GG5A 4FKCA 2NQ6A 1B59A 1XGMA 1PV9A 2BN7A 1XGNA 5E5BA 2B3LA 1C22A 3PEBA 3BIQA 1JAWA 3BITA 2GA2A 5FCHA 5JHUA 2Q96A 4IPAA 1MATA 4U6CA 4U6JA 4S00A 2GG7A 1YVMA 3FM3A 1BN5A 3I7MA 2GU4A 3IU9A 4QR8A 3RORA 4FLIA 1WLRA 5E2CA 3TAVA 2V6CA 2EVMA 2GG3A 5D6FA 5CDLA 4IKTA 4RGZ1 1QXYA 2G6PA 4U6ZA 1WBQA 3QOCA 4IDYA 4RZYA 2Q92A 4IU6A 1WKMA 2Q8KA 1M35A 1WY2A 1CHMA 2P9AA 5JFRA 2NQ7A 2P98A 4FO8A 4FUKA 4FLKA 1WL9A 4EGEA 4RZZA 2DFIA 3OOOA 2OAZA 4ZWUA 1YW8A 2GG8A 1BOAA 3TB5A 2BWUA 2BHCA 3IG4A 2BWVA 4S2TP 3CB6A 1XGSA 2Q93A 4OOKA 4U76A 4A6VA 2BHDA 2GU7A 2GU5A 4B28A 1YW7A 1A16A 4S01A 4A6WA 3PKAA 1C21A 1KQ9A 2GG2A 2GGCA 5CIKA 2B3HA 2V3XA 1B6AA 4PV4A 4PNCA 4U1BA 1WL6A 3FMQA 4FO7A 3FMRA 2Q94A 2BWSA 3IU8A 4FLLA 3IL0A 2GG0A 3MR1A 1QZYA 4Z7MA 2BWWA 2EVOA 3S6BA 3BIPA 3L7GA 2BH3A 1N51A 1YW9A 4ZWOA 2EA4A 4U6WA 5JI6A 4S2RP 5CLSA 1WN1A 2V3YA 4IKRA 1C27A 3OVKA 3PKCA 3RVAA 5CE6A 1C23A 2BHAA 1QXWA 3CTZA 2EVCA 4MATA 2ADUA 1O0XA 4U73A 3PKEA 1YJ3A 4U71A 1W7VA 3D27A 4U69A 3MATA 3CB5A 2V3ZA 2BHBA 3PKDA 4HXXA 2MATA 4U6EA
chains in the Genus database with same CATH topology
2OKNA 2Q95A 2HOWA 1KP0A 2GG9A 2BWXA 3O5VA 5CNXA 2P99A 1C24A 5CDVA 4IKUA 3L24A 1R5HA 4KM3A 3MX6A 1Y1NA 4FLJA 1W2MA 1R58A 2GGBA 2GZ5A 2BWTA 3Q6DA 2BB7A 2EA2A 4U70A 5D6EA 4IKSA 2ZSGA 4IECA 3PN9A 5FCFA 3IU7A 4ZNGA 1QXZA 2B3KA 4U75A 1XNZA 2IW2A 5CDEA 1R5GA 2BWYA 1KQ0A 2GTXA 4R60A 2GU6A 1XGOA 4IF7A 3PKBA 4JUQA 4ZWPA 2GG5A 4FKCA 2NQ6A 1B59A 1XGMA 1PV9A 2BN7A 1XGNA 5E5BA 2B3LA 1C22A 3PEBA 3BIQA 1JAWA 3BITA 2GA2A 5FCHA 5JHUA 2Q96A 4IPAA 1MATA 4U6CA 4U6JA 4S00A 2GG7A 1YVMA 3FM3A 1BN5A 3I7MA 2GU4A 3IU9A 4QR8A 3RORA 4FLIA 1WLRA 5E2CA 3TAVA 2V6CA 2EVMA 2GG3A 5D6FA 5CDLA 4IKTA 4RGZ1 1QXYA 2G6PA 4U6ZA 1WBQA 3QOCA 4IDYA 4RZYA 2Q92A 4IU6A 1WKMA 2Q8KA 1M35A 1WY2A 1CHMA 2P9AA 5JFRA 2NQ7A 2P98A 4FO8A 4FUKA 4FLKA 1WL9A 4EGEA 4RZZA 2DFIA 3OOOA 2OAZA 4ZWUA 1YW8A 2GG8A 1BOAA 3TB5A 2BWUA 2BHCA 3IG4A 2BWVA 4S2TP 3CB6A 1XGSA 2Q93A 4OOKA 4U76A 4A6VA 2BHDA 2GU7A 2GU5A 4B28A 1YW7A 1A16A 4S01A 4A6WA 3PKAA 1C21A 1KQ9A 2GG2A 2GGCA 5CIKA 2B3HA 2V3XA 1B6AA 4PV4A 4PNCA 4U1BA 1WL6A 3FMQA 4FO7A 3FMRA 2Q94A 2BWSA 3IU8A 4FLLA 3IL0A 2GG0A 3MR1A 1QZYA 4Z7MA 2BWWA 2EVOA 3S6BA 3BIPA 3L7GA 2BH3A 1N51A 1YW9A 4ZWOA 2EA4A 4U6WA 5JI6A 4S2RP 5CLSA 1WN1A 2V3YA 4IKRA 1C27A 3OVKA 3PKCA 3RVAA 5CE6A 1C23A 2BHAA 1QXWA 3CTZA 2EVCA 4MATA 2ADUA 1O0XA 4U73A 3PKEA 1YJ3A 4U71A 1W7VA 3D27A 4U69A 3MATA 3CB5A 2V3ZA 2BHBA 3PKDA 4HXXA 2MATA 4U6EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OKN A;  2Q95 A;  2HOW A;  1KP0 A;  2GG9 A;  2BWX A;  3O5V A;  5CNX A;  2P99 A;  1C24 A;  5CDV A;  4IKU A;  3L24 A;  1R5H A;  4KM3 A;  3MX6 A;  1Y1N A;  4FLJ A;  1W2M A;  1R58 A;  2GGB A;  2GZ5 A;  2BWT A;  3Q6D A;  2BB7 A;  2EA2 A;  4U70 A;  5D6E A;  4IKS A;  2ZSG A;  4IEC A;  3PN9 A;  5FCF A;  3IU7 A;  4ZNG A;  1QXZ A;  2B3K A;  4U75 A;  1XNZ A;  2IW2 A;  5CDE A;  1R5G A;  2BWY A;  1KQ0 A;  2GTX A;  4R60 A;  2GU6 A;  1XGO A;  4IF7 A;  3PKB A;  4JUQ A;  4ZWP A;  2GG5 A;  4FKC A;  2NQ6 A;  1B59 A;  1XGM A;  1PV9 A;  2BN7 A;  1XGN A;  5E5B A;  2B3L A;  1C22 A;  3PEB A;  3BIQ A;  1JAW A;  3BIT A;  2GA2 A;  5FCH A;  5JHU A;  2Q96 A;  4IPA A;  1MAT A;  4U6C A;  4U6J A;  4S00 A;  2GG7 A;  1YVM A;  3FM3 A;  1BN5 A;  3I7M A;  2GU4 A;  3IU9 A;  4QR8 A;  3ROR A;  4FLI A;  1WLR A;  5E2C A;  3TAV A;  2V6C A;  2EVM A;  2GG3 A;  5D6F A;  5CDL A;  4IKT A;  4RGZ 1;  1QXY A;  2G6P A;  4U6Z A;  1WBQ A;  3QOC A;  4IDY A;  4RZY A;  2Q92 A;  4IU6 A;  1WKM A;  2Q8K A;  1M35 A;  1WY2 A;  1CHM A;  2P9A A;  5JFR A;  2NQ7 A;  2P98 A;  4FO8 A;  4FUK A;  4FLK A;  1WL9 A;  4EGE A;  4RZZ A;  2DFI A;  3OOO A;  2OAZ A;  4ZWU A;  1YW8 A;  2GG8 A;  1BOA A;  3TB5 A;  2BWU A;  2BHC A;  3IG4 A;  2BWV A;  4S2T P;  3CB6 A;  1XGS A;  2Q93 A;  4OOK A;  4U76 A;  4A6V A;  2BHD A;  2GU7 A;  2GU5 A;  4B28 A;  1YW7 A;  1A16 A;  4S01 A;  4A6W A;  3PKA A;  1C21 A;  1KQ9 A;  2GG2 A;  2GGC A;  5CIK A;  2B3H A;  2V3X A;  1B6A A;  4PV4 A;  4PNC A;  4U1B A;  1WL6 A;  3FMQ A;  4FO7 A;  3FMR A;  2Q94 A;  2BWS A;  3IU8 A;  4FLL A;  3IL0 A;  2GG0 A;  3MR1 A;  1QZY A;  4Z7M A;  2BWW A;  2EVO A;  3S6B A;  3BIP A;  3L7G A;  2BH3 A;  1N51 A;  1YW9 A;  4ZWO A;  2EA4 A;  4U6W A;  5JI6 A;  4S2R P;  5CLS A;  1WN1 A;  2V3Y A;  4IKR A;  1C27 A;  3OVK A;  3PKC A;  3RVA A;  5CE6 A;  1C23 A;  2BHA A;  1QXW A;  3CTZ A;  2EVC A;  4MAT A;  2ADU A;  1O0X A;  4U73 A;  3PKE A;  1YJ3 A;  4U71 A;  1W7V A;  3D27 A;  4U69 A;  3MAT A;  3CB5 A;  2V3Z A;  2BHB A;  3PKD A;  4HXX A;  2MAT A;  4U6E A; 
#chains in the Genus database with same CATH topology
 2OKN A;  2Q95 A;  2HOW A;  1KP0 A;  2GG9 A;  2BWX A;  3O5V A;  5CNX A;  2P99 A;  1C24 A;  5CDV A;  4IKU A;  3L24 A;  1R5H A;  4KM3 A;  3MX6 A;  1Y1N A;  4FLJ A;  1W2M A;  1R58 A;  2GGB A;  2GZ5 A;  2BWT A;  3Q6D A;  2BB7 A;  2EA2 A;  4U70 A;  5D6E A;  4IKS A;  2ZSG A;  4IEC A;  3PN9 A;  5FCF A;  3IU7 A;  4ZNG A;  1QXZ A;  2B3K A;  4U75 A;  1XNZ A;  2IW2 A;  5CDE A;  1R5G A;  2BWY A;  1KQ0 A;  2GTX A;  4R60 A;  2GU6 A;  1XGO A;  4IF7 A;  3PKB A;  4JUQ A;  4ZWP A;  2GG5 A;  4FKC A;  2NQ6 A;  1B59 A;  1XGM A;  1PV9 A;  2BN7 A;  1XGN A;  5E5B A;  2B3L A;  1C22 A;  3PEB A;  3BIQ A;  1JAW A;  3BIT A;  2GA2 A;  5FCH A;  5JHU A;  2Q96 A;  4IPA A;  1MAT A;  4U6C A;  4U6J A;  4S00 A;  2GG7 A;  1YVM A;  3FM3 A;  1BN5 A;  3I7M A;  2GU4 A;  3IU9 A;  4QR8 A;  3ROR A;  4FLI A;  1WLR A;  5E2C A;  3TAV A;  2V6C A;  2EVM A;  2GG3 A;  5D6F A;  5CDL A;  4IKT A;  4RGZ 1;  1QXY A;  2G6P A;  4U6Z A;  1WBQ A;  3QOC A;  4IDY A;  4RZY A;  2Q92 A;  4IU6 A;  1WKM A;  2Q8K A;  1M35 A;  1WY2 A;  1CHM A;  2P9A A;  5JFR A;  2NQ7 A;  2P98 A;  4FO8 A;  4FUK A;  4FLK A;  1WL9 A;  4EGE A;  4RZZ A;  2DFI A;  3OOO A;  2OAZ A;  4ZWU A;  1YW8 A;  2GG8 A;  1BOA A;  3TB5 A;  2BWU A;  2BHC A;  3IG4 A;  2BWV A;  4S2T P;  3CB6 A;  1XGS A;  2Q93 A;  4OOK A;  4U76 A;  4A6V A;  2BHD A;  2GU7 A;  2GU5 A;  4B28 A;  1YW7 A;  1A16 A;  4S01 A;  4A6W A;  3PKA A;  1C21 A;  1KQ9 A;  2GG2 A;  2GGC A;  5CIK A;  2B3H A;  2V3X A;  1B6A A;  4PV4 A;  4PNC A;  4U1B A;  1WL6 A;  3FMQ A;  4FO7 A;  3FMR A;  2Q94 A;  2BWS A;  3IU8 A;  4FLL A;  3IL0 A;  2GG0 A;  3MR1 A;  1QZY A;  4Z7M A;  2BWW A;  2EVO A;  3S6B A;  3BIP A;  3L7G A;  2BH3 A;  1N51 A;  1YW9 A;  4ZWO A;  2EA4 A;  4U6W A;  5JI6 A;  4S2R P;  5CLS A;  1WN1 A;  2V3Y A;  4IKR A;  1C27 A;  3OVK A;  3PKC A;  3RVA A;  5CE6 A;  1C23 A;  2BHA A;  1QXW A;  3CTZ A;  2EVC A;  4MAT A;  2ADU A;  1O0X A;  4U73 A;  3PKE A;  1YJ3 A;  4U71 A;  1W7V A;  3D27 A;  4U69 A;  3MAT A;  3CB5 A;  2V3Z A;  2BHB A;  3PKD A;  4HXX A;  2MAT A;  4U6E A; 
#chains in the Genus database with same CATH homology
 2OKN A;  2Q95 A;  2HOW A;  1KP0 A;  2GG9 A;  2BWX A;  3O5V A;  5CNX A;  2P99 A;  1C24 A;  5CDV A;  4IKU A;  3L24 A;  1R5H A;  4KM3 A;  3MX6 A;  1Y1N A;  4FLJ A;  1W2M A;  1R58 A;  2GGB A;  2GZ5 A;  2BWT A;  3Q6D A;  2BB7 A;  2EA2 A;  4U70 A;  5D6E A;  4IKS A;  2ZSG A;  4IEC A;  3PN9 A;  5FCF A;  3IU7 A;  4ZNG A;  1QXZ A;  2B3K A;  4U75 A;  1XNZ A;  2IW2 A;  5CDE A;  1R5G A;  2BWY A;  1KQ0 A;  2GTX A;  4R60 A;  2GU6 A;  1XGO A;  4IF7 A;  3PKB A;  4JUQ A;  4ZWP A;  2GG5 A;  4FKC A;  2NQ6 A;  1B59 A;  1XGM A;  1PV9 A;  2BN7 A;  1XGN A;  5E5B A;  2B3L A;  1C22 A;  3PEB A;  3BIQ A;  1JAW A;  3BIT A;  2GA2 A;  5FCH A;  5JHU A;  2Q96 A;  4IPA A;  1MAT A;  4U6C A;  4U6J A;  4S00 A;  2GG7 A;  1YVM A;  3FM3 A;  1BN5 A;  3I7M A;  2GU4 A;  3IU9 A;  4QR8 A;  3ROR A;  4FLI A;  1WLR A;  5E2C A;  3TAV A;  2V6C A;  2EVM A;  2GG3 A;  5D6F A;  5CDL A;  4IKT A;  4RGZ 1;  1QXY A;  2G6P A;  4U6Z A;  1WBQ A;  3QOC A;  4IDY A;  4RZY A;  2Q92 A;  4IU6 A;  1WKM A;  2Q8K A;  1M35 A;  1WY2 A;  1CHM A;  2P9A A;  5JFR A;  2NQ7 A;  2P98 A;  4FO8 A;  4FUK A;  4FLK A;  1WL9 A;  4EGE A;  4RZZ A;  2DFI A;  3OOO A;  2OAZ A;  4ZWU A;  1YW8 A;  2GG8 A;  1BOA A;  3TB5 A;  2BWU A;  2BHC A;  3IG4 A;  2BWV A;  4S2T P;  3CB6 A;  1XGS A;  2Q93 A;  4OOK A;  4U76 A;  4A6V A;  2BHD A;  2GU7 A;  2GU5 A;  4B28 A;  1YW7 A;  1A16 A;  4S01 A;  4A6W A;  3PKA A;  1C21 A;  1KQ9 A;  2GG2 A;  2GGC A;  5CIK A;  2B3H A;  2V3X A;  1B6A A;  4PV4 A;  4PNC A;  4U1B A;  1WL6 A;  3FMQ A;  4FO7 A;  3FMR A;  2Q94 A;  2BWS A;  3IU8 A;  4FLL A;  3IL0 A;  2GG0 A;  3MR1 A;  1QZY A;  4Z7M A;  2BWW A;  2EVO A;  3S6B A;  3BIP A;  3L7G A;  2BH3 A;  1N51 A;  1YW9 A;  4ZWO A;  2EA4 A;  4U6W A;  5JI6 A;  4S2R P;  5CLS A;  1WN1 A;  2V3Y A;  4IKR A;  1C27 A;  3OVK A;  3PKC A;  3RVA A;  5CE6 A;  1C23 A;  2BHA A;  1QXW A;  3CTZ A;  2EVC A;  4MAT A;  2ADU A;  1O0X A;  4U73 A;  3PKE A;  1YJ3 A;  4U71 A;  1W7V A;  3D27 A;  4U69 A;  3MAT A;  3CB5 A;  2V3Z A;  2BHB A;  3PKD A;  4HXX A;  2MAT A;  4U6E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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