1EZFA

Crystal structure of human squalene synthase
Total Genus 131
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
131
sequence length
333
structure length
323
Chain Sequence
NSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
source organism Homo sapiens
publication title Crystal structure of human squalene synthase. A key enzyme in cholesterol biosynthesis.
pubmed doi rcsb
molecule keywords FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE
total genus 131
structure length 323
sequence length 333
chains with identical sequence B, C
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2000-05-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 1ezfA00
1N24A 4FJQA 3N46F 4KPJA 3RMGA 3LOMA 2Q9ZA 4H5DF 1WL0A 4F62A 4ZQ8A 2ZEUA 3ID0A 5IL8A 5IKHA 3N0GA 3WCLA 3WCJA 1KIZA 1V4JA 2ZCSA 4NFJF 4P0XA 5EAUA 1VG4A 1EZFA 2E92A 3N1WF 3TFNA 4QPFA 4DI5A 3WEJA 2Q58A 2Z4YA 3PH7A 5DZ2A 1WY0A 3RYEA 5IK6A 4LPHF 1FPSA 2Z78A 3AE0A 3WEFA 3M00A 3NPKA 4N1ZF 5ILIA 3MAVA 3CKEA 4H5CF 2PS6A 3G4FA 2E93A 1HXCA 4LFEA 3KRFB 5ILZA 3MZVA 5B02A 3IPIA 3AQBB 4KVWA 2F94F 5EASA 2PS5A 5AFXA 1PS1A 3KROA 3AQ0A 4XQSF 3VJBA 4N9UA 3NF2A 2O1OA 5DJRF 2PS7A 4H5EF 1V4HA 1WMWA 2Z4VA 3P41A 3Q1OA 4LFGA 1YHKA 2ZCRA 1VG7A 5A0JA 5DIQF 2J5CA 3WCCA 5ILHA 4MC0A 4JXNA 3S9VA 2E8WA 3N3DA 4JYXA 4DHDA 5JUZF 4FP4A 3KRCA 3V1VA 3ACYA 4KFAA 2ZCOA 4EA2A 3SDQA 3OACA 3TFPA 3OABA 3TS7A 4K10A 4MC8A 3Q30A 4NFKF 3S4JA 3ZCDA 4KVIA 3ADZA 3ZMBA 4LPGF 4LOBA 3ZL6A 4E1EA 5A0IA 3BNXA 3PKOA 4JVJF 4NUAA 2DH4A 3EGTA 4QXSF 1UBXA 5DW7A 4KQUA 4OMHA 4P0WA 2Z52A 1KIYA 3NRIA 1HXAA 4GAXA 1YYSA 3WCGA 3SDUA 4GA3A 1WL1A 3WEIA 4P0VA 1RQIA 4RXAA 5IVGA 4LA5A 3DYHA 3CC9A 5ILYA 2I19A 4XQRF 4PVYF 3WSAA 4MC3A 3LMDA 5DJPF 1YHMA 4Q23A 3VJEA 2E90A 3ZMCA 4KQ5A 1DGPA 2AELA 4LLTA 4EA1A 3KROB 5E8HA 3VJAA 2ZEVA 3ICZA 5B03A 5B0KA 4NG6A 2ZCQA 3WJKA 3M9UA 1N23A 3WSBA 1ZW5A 3WCMA 3LGKA 4LXWA 1VG3A 3AQCB 1YJ4A 3P8LA 3PYAA 2F8CF 3LLWA 4NKFA 3TC1A 2E94A 5B0LA 2F7MF 3KRCB 4JZXA 5IN8A 3W7FA 3OACB 2E8VA 3OABB 4EA0A 5DGMF 3P5PA 4GP1A 1YYTA 1N22A 5HN7A 4RXEA 4KPDA 3WEKA 2J1OA 3LGZB 5DHKA 4JXYA 3VJ8A 3M0GA 5IMPA 3WEHA 2E4OA 3Q2ZA 2AZLA 1V4IA 3DYFA 2ONHA 2E8XA 4KUXA 3BNYA 4RXDA 5IK0A 2FTZA 4PVXF 5JV2F 3WCEA 1YYRA 2F8ZF 5ILKA 3N45F 2E8UA 2AZJA 3B7LA 1N1ZA 2E8TA 3KBKA 3SDVA 4WK5A 3RYWA 5ER8A 3EFQA 2EWGA 5ILJA 3KRPA 5ILDA 4L2XF 1HM4A 3ACWA 1HM7A 1WL3A 2OGDA 4LFVF 3WCAA 3V66A 5IM1A 3VJCA 2OPMA 5AHUB 5B0MA 2Q9YA 5H9DA 2RAHA 4LLSA 3WCIA 1VG2A 3APZA 3ZOUA 5ERNA 2Z4WA 4KKMA 3N5HF 4LZCA 4RNQA 2F92F 2FORA 4LTZA 3LG5A 3LZ9A 2PS8A 3PYBA 4KVYA 5C05A 3LSNA 3WJOA 1YV5A 3VJDA 3LJIA 3SDRA 5A0KA 5JA0F 5B0IA 4GP2A 5JV1F 1HX9A 3WJNA 1WKZA 5CG5A 3N49F 5IL3A 3NPRA 3WCHA 5KSXF 4NKEA 3M01A 1YYUA 3P5RA 1N1BA 3N6KF 2E95A 1JFAA 1VG6A 5EATA 5DHIA 3WCBA 3LEEA 4LIXA 3KRAA 1V4KA 4NFIF 3KB9A 3WC9A 1RQJA 4OMGA 4OKMA 4JZBA 2OPNA 3ASXA 5JV0F 1YHLA 2AEKA 3CP6A 1V4EA 3ACXA 5B01A 5B00A 3ICMA 1HXGA 2AETA 5HN8A 3Q2QA 1RTRA 1UBVA 4HD1A 2QISA 3N0FA 3ICNA 3KRPB 3QQVA 4XQTF 2OA6A 4RXCA 3WCFA 2Z50A 4E9ZA 2Z7IA 4F6XA 5IMIA 5IMNA 3ICKA 3TFVA 2ONGA 5E8LA 3N3LF 3WE9A 4LZ3A 2E91A 4E9UA 2VF6A 3PDEA 4DWGA 1YYQA 5IK9A 2PS4A 1DI1A 2Z4ZA 2Z4XA 2J1PA 3IBAA 3DYGA 3VJ9A 5IKAA 3EZ3A 5HN9A 4KWDA 1JFGA 4RYPA 4LUUA 5CG6A 1UBWA 4UMJA 3LK5A 3G4DA 4KVDA 5EROA 5I1UA 3KRFA 4DZWA 3QKCA 5AELA 2F9KF 2H8OA 1N21A 1WL2A 5E8KA 5ERMA 2P1CA 3UCAA 3V1XA 3SAEA 4DWBA 3P8RA 5DGSF 4OKZA 3WEGA 4KQSA 3LDWA 3RBMA 3SDTA 1UBYA 2Z7HA 5B0JA 1YQ7A 2F89F 3KRAB 2Q80A 4F6VA 2AZKA 5HNAA 5DGNF 4LA6A 3LVSA 4KK2A 2ZY1A 4OGUA 3OYRA 5AYPA 3WCDA 4LTVA 5DJVF 1N20A 3N1VF 4DEMF 4DXJA 3N5JF 4LZ0A 3M02A
chains in the Genus database with same CATH superfamily
1N24A 4FJQA 3N46F 4KPJA 3RMGA 3LOMA 2Q9ZA 4H5DF 1WL0A 4F62A 4ZQ8A 2ZEUA 3ID0A 5IL8A 5IKHA 3N0GA 3WCLA 3WCJA 1KIZA 1V4JA 2ZCSA 4NFJF 4P0XA 5EAUA 1VG4A 1EZFA 2E92A 3N1WF 3TFNA 4QPFA 4DI5A 3WEJA 2Q58A 2Z4YA 3PH7A 5DZ2A 1WY0A 3RYEA 5IK6A 4LPHF 1FPSA 2Z78A 3AE0A 3WEFA 3M00A 3NPKA 4N1ZF 5ILIA 3MAVA 3CKEA 4H5CF 2PS6A 3G4FA 2E93A 1HXCA 4LFEA 3KRFB 5ILZA 3MZVA 5B02A 3IPIA 3AQBB 4KVWA 2F94F 5EASA 2PS5A 5AFXA 1PS1A 3KROA 3AQ0A 4XQSF 3VJBA 4N9UA 3NF2A 2O1OA 5DJRF 2PS7A 4H5EF 1V4HA 1WMWA 2Z4VA 3P41A 3Q1OA 4LFGA 1YHKA 2ZCRA 1VG7A 5A0JA 5DIQF 2J5CA 3WCCA 5ILHA 4MC0A 4JXNA 3S9VA 2E8WA 3N3DA 4JYXA 4DHDA 5JUZF 4FP4A 3KRCA 3V1VA 3ACYA 4KFAA 2ZCOA 4EA2A 3SDQA 3OACA 3TFPA 3OABA 3TS7A 4K10A 4MC8A 3Q30A 4NFKF 3S4JA 3ZCDA 4KVIA 3ADZA 3ZMBA 4LPGF 4LOBA 3ZL6A 4E1EA 5A0IA 3BNXA 3PKOA 4JVJF 4NUAA 2DH4A 3EGTA 4QXSF 1UBXA 5DW7A 4KQUA 4OMHA 4P0WA 2Z52A 1KIYA 3NRIA 1HXAA 4GAXA 1YYSA 3WCGA 3SDUA 4GA3A 1WL1A 3WEIA 4P0VA 1RQIA 4RXAA 5IVGA 4LA5A 3DYHA 3CC9A 5ILYA 2I19A 4XQRF 4PVYF 3WSAA 4MC3A 3LMDA 5DJPF 1YHMA 4Q23A 3VJEA 2E90A 3ZMCA 4KQ5A 1DGPA 2AELA 4LLTA 4EA1A 3KROB 5E8HA 3VJAA 2ZEVA 3ICZA 5B03A 5B0KA 4NG6A 2ZCQA 3WJKA 3M9UA 1N23A 3WSBA 1ZW5A 3WCMA 3LGKA 4LXWA 1VG3A 3AQCB 1YJ4A 3P8LA 3PYAA 2F8CF 3LLWA 4NKFA 3TC1A 2E94A 5B0LA 2F7MF 3KRCB 4JZXA 5IN8A 3W7FA 3OACB 2E8VA 3OABB 4EA0A 5DGMF 3P5PA 4GP1A 1YYTA 1N22A 5HN7A 4RXEA 4KPDA 3WEKA 2J1OA 3LGZB 5DHKA 4JXYA 3VJ8A 3M0GA 5IMPA 3WEHA 2E4OA 3Q2ZA 2AZLA 1V4IA 3DYFA 2ONHA 2E8XA 4KUXA 3BNYA 4RXDA 5IK0A 2FTZA 4PVXF 5JV2F 3WCEA 1YYRA 2F8ZF 5ILKA 3N45F 2E8UA 2AZJA 3B7LA 1N1ZA 2E8TA 3KBKA 3SDVA 4WK5A 3RYWA 5ER8A 3EFQA 2EWGA 5ILJA 3KRPA 5ILDA 4L2XF 1HM4A 3ACWA 1HM7A 1WL3A 2OGDA 4LFVF 3WCAA 3V66A 5IM1A 3VJCA 2OPMA 5AHUB 5B0MA 2Q9YA 5H9DA 2RAHA 4LLSA 3WCIA 1VG2A 3APZA 3ZOUA 5ERNA 2Z4WA 4KKMA 3N5HF 4LZCA 4RNQA 2F92F 2FORA 4LTZA 3LG5A 3LZ9A 2PS8A 3PYBA 4KVYA 5C05A 3LSNA 3WJOA 1YV5A 3VJDA 3LJIA 3SDRA 5A0KA 5JA0F 5B0IA 4GP2A 5JV1F 1HX9A 3WJNA 1WKZA 5CG5A 3N49F 5IL3A 3NPRA 3WCHA 5KSXF 4NKEA 3M01A 1YYUA 3P5RA 1N1BA 3N6KF 2E95A 1JFAA 1VG6A 5EATA 5DHIA 3WCBA 3LEEA 4LIXA 3KRAA 1V4KA 4NFIF 3KB9A 3WC9A 1RQJA 4OMGA 4OKMA 4JZBA 2OPNA 3ASXA 5JV0F 1YHLA 2AEKA 3CP6A 1V4EA 3ACXA 5B01A 5B00A 3ICMA 1HXGA 2AETA 5HN8A 3Q2QA 1RTRA 1UBVA 4HD1A 2QISA 3N0FA 3ICNA 3KRPB 3QQVA 4XQTF 2OA6A 4RXCA 3WCFA 2Z50A 4E9ZA 2Z7IA 4F6XA 5IMIA 5IMNA 3ICKA 3TFVA 2ONGA 5E8LA 3N3LF 3WE9A 4LZ3A 2E91A 4E9UA 2VF6A 3PDEA 4DWGA 1YYQA 5IK9A 2PS4A 1DI1A 2Z4ZA 2Z4XA 2J1PA 3IBAA 3DYGA 3VJ9A 5IKAA 3EZ3A 5HN9A 4KWDA 1JFGA 4RYPA 4LUUA 5CG6A 1UBWA 4UMJA 3LK5A 3G4DA 4KVDA 5EROA 5I1UA 3KRFA 4DZWA 3QKCA 5AELA 2F9KF 2H8OA 1N21A 1WL2A 5E8KA 5ERMA 2P1CA 3UCAA 3V1XA 3SAEA 4DWBA 3P8RA 5DGSF 4OKZA 3WEGA 4KQSA 3LDWA 3RBMA 3SDTA 1UBYA 2Z7HA 5B0JA 1YQ7A 2F89F 3KRAB 2Q80A 4F6VA 2AZKA 5HNAA 5DGNF 4LA6A 3LVSA 4KK2A 2ZY1A 4OGUA 3OYRA 5AYPA 3WCDA 4LTVA 5DJVF 1N20A 3N1VF 4DEMF 4DXJA 3N5JF 4LZ0A 3M02A
chains in the Genus database with same CATH topology
1N24A 4FJQA 3N46F 4KPJA 3RMGA 3LOMA 2Q9ZA 4H5DF 1WL0A 4F62A 4ZQ8A 2ZEUA 3ID0A 5IL8A 5IKHA 3N0GA 3WCLA 3WCJA 1KIZA 1V4JA 2ZCSA 4NFJF 4P0XA 5EAUA 1VG4A 1EZFA 2E92A 3N1WF 3TFNA 4QPFA 4DI5A 3WEJA 2Q58A 2Z4YA 3PH7A 5DZ2A 1WY0A 3RYEA 5IK6A 4LPHF 1FPSA 2Z78A 3AE0A 3WEFA 3M00A 3NPKA 4N1ZF 5ILIA 3MAVA 3CKEA 4H5CF 2PS6A 3G4FA 2E93A 1HXCA 4LFEA 3KRFB 5ILZA 3MZVA 5B02A 3IPIA 3AQBB 4KVWA 2F94F 5EASA 2PS5A 5AFXA 1PS1A 3KROA 3AQ0A 4XQSF 3VJBA 4N9UA 3NF2A 2O1OA 5DJRF 2PS7A 4H5EF 1V4HA 1WMWA 2Z4VA 3P41A 3Q1OA 4LFGA 1YHKA 2ZCRA 1VG7A 5A0JA 5DIQF 2J5CA 3WCCA 5ILHA 4MC0A 4JXNA 3S9VA 2E8WA 3N3DA 4JYXA 4DHDA 5JUZF 4FP4A 3KRCA 3V1VA 3ACYA 4KFAA 2ZCOA 4EA2A 3SDQA 3OACA 3TFPA 3OABA 3TS7A 4K10A 4MC8A 3Q30A 4NFKF 3S4JA 3ZCDA 4KVIA 3ADZA 3ZMBA 4LPGF 4LOBA 3ZL6A 4E1EA 5A0IA 3BNXA 3PKOA 4JVJF 4NUAA 2DH4A 3EGTA 4QXSF 1UBXA 5DW7A 4KQUA 4OMHA 4P0WA 2Z52A 1KIYA 3NRIA 1HXAA 4GAXA 1YYSA 3WCGA 3SDUA 4GA3A 1WL1A 3WEIA 4P0VA 1RQIA 4RXAA 5IVGA 4LA5A 3DYHA 3CC9A 5ILYA 2I19A 4XQRF 4PVYF 3WSAA 4MC3A 3LMDA 5DJPF 1YHMA 4Q23A 3VJEA 2E90A 3ZMCA 4KQ5A 1DGPA 2AELA 4LLTA 4EA1A 3KROB 5E8HA 3VJAA 2ZEVA 3ICZA 5B03A 5B0KA 4NG6A 2ZCQA 3WJKA 3M9UA 1N23A 3WSBA 1ZW5A 3WCMA 3LGKA 4LXWA 1VG3A 3AQCB 1YJ4A 3P8LA 3PYAA 2F8CF 3LLWA 4NKFA 3TC1A 2E94A 5B0LA 2F7MF 3KRCB 4JZXA 5IN8A 3W7FA 3OACB 2E8VA 3OABB 4EA0A 5DGMF 3P5PA 4GP1A 1YYTA 1N22A 5HN7A 4RXEA 4KPDA 3WEKA 2J1OA 3LGZB 5DHKA 4JXYA 3VJ8A 3M0GA 5IMPA 3WEHA 2E4OA 3Q2ZA 2AZLA 1V4IA 3DYFA 2ONHA 2E8XA 4KUXA 3BNYA 4RXDA 5IK0A 2FTZA 4PVXF 5JV2F 3WCEA 1YYRA 2F8ZF 5ILKA 3N45F 2E8UA 2AZJA 3B7LA 1N1ZA 2E8TA 3KBKA 3SDVA 4WK5A 3RYWA 5ER8A 3EFQA 2EWGA 5ILJA 3KRPA 5ILDA 4L2XF 1HM4A 3ACWA 1HM7A 1WL3A 2OGDA 4LFVF 3WCAA 3V66A 5IM1A 3VJCA 2OPMA 5AHUB 5B0MA 2Q9YA 5H9DA 2RAHA 4LLSA 3WCIA 1VG2A 3APZA 3ZOUA 5ERNA 2Z4WA 4KKMA 3N5HF 4LZCA 4RNQA 2F92F 2FORA 4LTZA 3LG5A 3LZ9A 2PS8A 3PYBA 4KVYA 5C05A 3LSNA 3WJOA 1YV5A 3VJDA 3LJIA 3SDRA 5A0KA 5JA0F 5B0IA 4GP2A 5JV1F 1HX9A 3WJNA 1WKZA 5CG5A 3N49F 5IL3A 3NPRA 3WCHA 5KSXF 4NKEA 3M01A 1YYUA 3P5RA 1N1BA 3N6KF 2E95A 1JFAA 1VG6A 5EATA 5DHIA 3WCBA 3LEEA 4LIXA 3KRAA 1V4KA 4NFIF 3KB9A 3WC9A 1RQJA 4OMGA 4OKMA 4JZBA 2OPNA 3ASXA 5JV0F 1YHLA 2AEKA 3CP6A 1V4EA 3ACXA 5B01A 5B00A 3ICMA 1HXGA 2AETA 5HN8A 3Q2QA 1RTRA 1UBVA 4HD1A 2QISA 3N0FA 3ICNA 3KRPB 3QQVA 4XQTF 2OA6A 4RXCA 3WCFA 2Z50A 4E9ZA 2Z7IA 4F6XA 5IMIA 5IMNA 3ICKA 3TFVA 2ONGA 5E8LA 3N3LF 3WE9A 4LZ3A 2E91A 4E9UA 2VF6A 3PDEA 4DWGA 1YYQA 5IK9A 2PS4A 1DI1A 2Z4ZA 2Z4XA 2J1PA 3IBAA 3DYGA 3VJ9A 5IKAA 3EZ3A 5HN9A 4KWDA 1JFGA 4RYPA 4LUUA 5CG6A 1UBWA 4UMJA 3LK5A 3G4DA 4KVDA 5EROA 5I1UA 3KRFA 4DZWA 3QKCA 5AELA 2F9KF 2H8OA 1N21A 1WL2A 5E8KA 5ERMA 2P1CA 3UCAA 3V1XA 3SAEA 4DWBA 3P8RA 5DGSF 4OKZA 3WEGA 4KQSA 3LDWA 3RBMA 3SDTA 1UBYA 2Z7HA 5B0JA 1YQ7A 2F89F 3KRAB 2Q80A 4F6VA 2AZKA 5HNAA 5DGNF 4LA6A 3LVSA 4KK2A 2ZY1A 4OGUA 3OYRA 5AYPA 3WCDA 4LTVA 5DJVF 1N20A 3N1VF 4DEMF 4DXJA 3N5JF 4LZ0A 3M02A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1N24 A;  4FJQ A;  3N46 F;  4KPJ A;  3RMG A;  3LOM A;  2Q9Z A;  4H5D F;  1WL0 A;  4F62 A;  4ZQ8 A;  2ZEU A;  3ID0 A;  5IL8 A;  5IKH A;  3N0G A;  3WCL A;  3WCJ A;  1KIZ A;  1V4J A;  2ZCS A;  4NFJ F;  4P0X A;  5EAU A;  1VG4 A;  1EZF A;  2E92 A;  3N1W F;  3TFN A;  4QPF A;  4DI5 A;  3WEJ A;  2Q58 A;  2Z4Y A;  3PH7 A;  5DZ2 A;  1WY0 A;  3RYE A;  5IK6 A;  4LPH F;  1FPS A;  2Z78 A;  3AE0 A;  3WEF A;  3M00 A;  3NPK A;  4N1Z F;  5ILI A;  3MAV A;  3CKE A;  4H5C F;  2PS6 A;  3G4F A;  2E93 A;  1HXC A;  4LFE A;  3KRF B;  5ILZ A;  3MZV A;  5B02 A;  3IPI A;  3AQB B;  4KVW A;  2F94 F;  5EAS A;  2PS5 A;  5AFX A;  1PS1 A;  3KRO A;  3AQ0 A;  4XQS F;  3VJB A;  4N9U A;  3NF2 A;  2O1O A;  5DJR F;  2PS7 A;  4H5E F;  1V4H A;  1WMW A;  2Z4V A;  3P41 A;  3Q1O A;  4LFG A;  1YHK A;  2ZCR A;  1VG7 A;  5A0J A;  5DIQ F;  2J5C A;  3WCC A;  5ILH A;  4MC0 A;  4JXN A;  3S9V A;  2E8W A;  3N3D A;  4JYX A;  4DHD A;  5JUZ F;  4FP4 A;  3KRC A;  3V1V A;  3ACY A;  4KFA A;  2ZCO A;  4EA2 A;  3SDQ A;  3OAC A;  3TFP A;  3OAB A;  3TS7 A;  4K10 A;  4MC8 A;  3Q30 A;  4NFK F;  3S4J A;  3ZCD A;  4KVI A;  3ADZ A;  3ZMB A;  4LPG F;  4LOB A;  3ZL6 A;  4E1E A;  5A0I A;  3BNX A;  3PKO A;  4JVJ F;  4NUA A;  2DH4 A;  3EGT A;  4QXS F;  1UBX A;  5DW7 A;  4KQU A;  4OMH A;  4P0W A;  2Z52 A;  1KIY A;  3NRI A;  1HXA A;  4GAX A;  1YYS A;  3WCG A;  3SDU A;  4GA3 A;  1WL1 A;  3WEI A;  4P0V A;  1RQI A;  4RXA A;  5IVG A;  4LA5 A;  3DYH A;  3CC9 A;  5ILY A;  2I19 A;  4XQR F;  4PVY F;  3WSA A;  4MC3 A;  3LMD A;  5DJP F;  1YHM A;  4Q23 A;  3VJE A;  2E90 A;  3ZMC A;  4KQ5 A;  1DGP A;  2AEL A;  4LLT A;  4EA1 A;  3KRO B;  5E8H A;  3VJA A;  2ZEV A;  3ICZ A;  5B03 A;  5B0K A;  4NG6 A;  2ZCQ A;  3WJK A;  3M9U A;  1N23 A;  3WSB A;  1ZW5 A;  3WCM A;  3LGK A;  4LXW A;  1VG3 A;  3AQC B;  1YJ4 A;  3P8L A;  3PYA A;  2F8C F;  3LLW A;  4NKF A;  3TC1 A;  2E94 A;  5B0L A;  2F7M F;  3KRC B;  4JZX A;  5IN8 A;  3W7F A;  3OAC B;  2E8V A;  3OAB B;  4EA0 A;  5DGM F;  3P5P A;  4GP1 A;  1YYT A;  1N22 A;  5HN7 A;  4RXE A;  4KPD A;  3WEK A;  2J1O A;  3LGZ B;  5DHK A;  4JXY A;  3VJ8 A;  3M0G A;  5IMP A;  3WEH A;  2E4O A;  3Q2Z A;  2AZL A;  1V4I A;  3DYF A;  2ONH A;  2E8X A;  4KUX A;  3BNY A;  4RXD A;  5IK0 A;  2FTZ A;  4PVX F;  5JV2 F;  3WCE A;  1YYR A;  2F8Z F;  5ILK A;  3N45 F;  2E8U A;  2AZJ A;  3B7L A;  1N1Z A;  2E8T A;  3KBK A;  3SDV A;  4WK5 A;  3RYW A;  5ER8 A;  3EFQ A;  2EWG A;  5ILJ A;  3KRP A;  5ILD A;  4L2X F;  1HM4 A;  3ACW A;  1HM7 A;  1WL3 A;  2OGD A;  4LFV F;  3WCA A;  3V66 A;  5IM1 A;  3VJC A;  2OPM A;  5AHU B;  5B0M A;  2Q9Y A;  5H9D A;  2RAH A;  4LLS A;  3WCI A;  1VG2 A;  3APZ A;  3ZOU A;  5ERN A;  2Z4W A;  4KKM A;  3N5H F;  4LZC A;  4RNQ A;  2F92 F;  2FOR A;  4LTZ A;  3LG5 A;  3LZ9 A;  2PS8 A;  3PYB A;  4KVY A;  5C05 A;  3LSN A;  3WJO A;  1YV5 A;  3VJD A;  3LJI A;  3SDR A;  5A0K A;  5JA0 F;  5B0I A;  4GP2 A;  5JV1 F;  1HX9 A;  3WJN A;  1WKZ A;  5CG5 A;  3N49 F;  5IL3 A;  3NPR A;  3WCH A;  5KSX F;  4NKE A;  3M01 A;  1YYU A;  3P5R A;  1N1B A;  3N6K F;  2E95 A;  1JFA A;  1VG6 A;  5EAT A;  5DHI A;  3WCB A;  3LEE A;  4LIX A;  3KRA A;  1V4K A;  4NFI F;  3KB9 A;  3WC9 A;  1RQJ A;  4OMG A;  4OKM A;  4JZB A;  2OPN A;  3ASX A;  5JV0 F;  1YHL A;  2AEK A;  3CP6 A;  1V4E A;  3ACX A;  5B01 A;  5B00 A;  3ICM A;  1HXG A;  2AET A;  5HN8 A;  3Q2Q A;  1RTR A;  1UBV A;  4HD1 A;  2QIS A;  3N0F A;  3ICN A;  3KRP B;  3QQV A;  4XQT F;  2OA6 A;  4RXC A;  3WCF A;  2Z50 A;  4E9Z A;  2Z7I A;  4F6X A;  5IMI A;  5IMN A;  3ICK A;  3TFV A;  2ONG A;  5E8L A;  3N3L F;  3WE9 A;  4LZ3 A;  2E91 A;  4E9U A;  2VF6 A;  3PDE A;  4DWG A;  1YYQ A;  5IK9 A;  2PS4 A;  1DI1 A;  2Z4Z A;  2Z4X A;  2J1P A;  3IBA A;  3DYG A;  3VJ9 A;  5IKA A;  3EZ3 A;  5HN9 A;  4KWD A;  1JFG A;  4RYP A;  4LUU A;  5CG6 A;  1UBW A;  4UMJ A;  3LK5 A;  3G4D A;  4KVD A;  5ERO A;  5I1U A;  3KRF A;  4DZW A;  3QKC A;  5AEL A;  2F9K F;  2H8O A;  1N21 A;  1WL2 A;  5E8K A;  5ERM A;  2P1C A;  3UCA A;  3V1X A;  3SAE A;  4DWB A;  3P8R A;  5DGS F;  4OKZ A;  3WEG A;  4KQS A;  3LDW A;  3RBM A;  3SDT A;  1UBY A;  2Z7H A;  5B0J A;  1YQ7 A;  2F89 F;  3KRA B;  2Q80 A;  4F6V A;  2AZK A;  5HNA A;  5DGN F;  4LA6 A;  3LVS A;  4KK2 A;  2ZY1 A;  4OGU A;  3OYR A;  5AYP A;  3WCD A;  4LTV A;  5DJV F;  1N20 A;  3N1V F;  4DEM F;  4DXJ A;  3N5J F;  4LZ0 A;  3M02 A; 
#chains in the Genus database with same CATH topology
 1N24 A;  4FJQ A;  3N46 F;  4KPJ A;  3RMG A;  3LOM A;  2Q9Z A;  4H5D F;  1WL0 A;  4F62 A;  4ZQ8 A;  2ZEU A;  3ID0 A;  5IL8 A;  5IKH A;  3N0G A;  3WCL A;  3WCJ A;  1KIZ A;  1V4J A;  2ZCS A;  4NFJ F;  4P0X A;  5EAU A;  1VG4 A;  1EZF A;  2E92 A;  3N1W F;  3TFN A;  4QPF A;  4DI5 A;  3WEJ A;  2Q58 A;  2Z4Y A;  3PH7 A;  5DZ2 A;  1WY0 A;  3RYE A;  5IK6 A;  4LPH F;  1FPS A;  2Z78 A;  3AE0 A;  3WEF A;  3M00 A;  3NPK A;  4N1Z F;  5ILI A;  3MAV A;  3CKE A;  4H5C F;  2PS6 A;  3G4F A;  2E93 A;  1HXC A;  4LFE A;  3KRF B;  5ILZ A;  3MZV A;  5B02 A;  3IPI A;  3AQB B;  4KVW A;  2F94 F;  5EAS A;  2PS5 A;  5AFX A;  1PS1 A;  3KRO A;  3AQ0 A;  4XQS F;  3VJB A;  4N9U A;  3NF2 A;  2O1O A;  5DJR F;  2PS7 A;  4H5E F;  1V4H A;  1WMW A;  2Z4V A;  3P41 A;  3Q1O A;  4LFG A;  1YHK A;  2ZCR A;  1VG7 A;  5A0J A;  5DIQ F;  2J5C A;  3WCC A;  5ILH A;  4MC0 A;  4JXN A;  3S9V A;  2E8W A;  3N3D A;  4JYX A;  4DHD A;  5JUZ F;  4FP4 A;  3KRC A;  3V1V A;  3ACY A;  4KFA A;  2ZCO A;  4EA2 A;  3SDQ A;  3OAC A;  3TFP A;  3OAB A;  3TS7 A;  4K10 A;  4MC8 A;  3Q30 A;  4NFK F;  3S4J A;  3ZCD A;  4KVI A;  3ADZ A;  3ZMB A;  4LPG F;  4LOB A;  3ZL6 A;  4E1E A;  5A0I A;  3BNX A;  3PKO A;  4JVJ F;  4NUA A;  2DH4 A;  3EGT A;  4QXS F;  1UBX A;  5DW7 A;  4KQU A;  4OMH A;  4P0W A;  2Z52 A;  1KIY A;  3NRI A;  1HXA A;  4GAX A;  1YYS A;  3WCG A;  3SDU A;  4GA3 A;  1WL1 A;  3WEI A;  4P0V A;  1RQI A;  4RXA A;  5IVG A;  4LA5 A;  3DYH A;  3CC9 A;  5ILY A;  2I19 A;  4XQR F;  4PVY F;  3WSA A;  4MC3 A;  3LMD A;  5DJP F;  1YHM A;  4Q23 A;  3VJE A;  2E90 A;  3ZMC A;  4KQ5 A;  1DGP A;  2AEL A;  4LLT A;  4EA1 A;  3KRO B;  5E8H A;  3VJA A;  2ZEV A;  3ICZ A;  5B03 A;  5B0K A;  4NG6 A;  2ZCQ A;  3WJK A;  3M9U A;  1N23 A;  3WSB A;  1ZW5 A;  3WCM A;  3LGK A;  4LXW A;  1VG3 A;  3AQC B;  1YJ4 A;  3P8L A;  3PYA A;  2F8C F;  3LLW A;  4NKF A;  3TC1 A;  2E94 A;  5B0L A;  2F7M F;  3KRC B;  4JZX A;  5IN8 A;  3W7F A;  3OAC B;  2E8V A;  3OAB B;  4EA0 A;  5DGM F;  3P5P A;  4GP1 A;  1YYT A;  1N22 A;  5HN7 A;  4RXE A;  4KPD A;  3WEK A;  2J1O A;  3LGZ B;  5DHK A;  4JXY A;  3VJ8 A;  3M0G A;  5IMP A;  3WEH A;  2E4O A;  3Q2Z A;  2AZL A;  1V4I A;  3DYF A;  2ONH A;  2E8X A;  4KUX A;  3BNY A;  4RXD A;  5IK0 A;  2FTZ A;  4PVX F;  5JV2 F;  3WCE A;  1YYR A;  2F8Z F;  5ILK A;  3N45 F;  2E8U A;  2AZJ A;  3B7L A;  1N1Z A;  2E8T A;  3KBK A;  3SDV A;  4WK5 A;  3RYW A;  5ER8 A;  3EFQ A;  2EWG A;  5ILJ A;  3KRP A;  5ILD A;  4L2X F;  1HM4 A;  3ACW A;  1HM7 A;  1WL3 A;  2OGD A;  4LFV F;  3WCA A;  3V66 A;  5IM1 A;  3VJC A;  2OPM A;  5AHU B;  5B0M A;  2Q9Y A;  5H9D A;  2RAH A;  4LLS A;  3WCI A;  1VG2 A;  3APZ A;  3ZOU A;  5ERN A;  2Z4W A;  4KKM A;  3N5H F;  4LZC A;  4RNQ A;  2F92 F;  2FOR A;  4LTZ A;  3LG5 A;  3LZ9 A;  2PS8 A;  3PYB A;  4KVY A;  5C05 A;  3LSN A;  3WJO A;  1YV5 A;  3VJD A;  3LJI A;  3SDR A;  5A0K A;  5JA0 F;  5B0I A;  4GP2 A;  5JV1 F;  1HX9 A;  3WJN A;  1WKZ A;  5CG5 A;  3N49 F;  5IL3 A;  3NPR A;  3WCH A;  5KSX F;  4NKE A;  3M01 A;  1YYU A;  3P5R A;  1N1B A;  3N6K F;  2E95 A;  1JFA A;  1VG6 A;  5EAT A;  5DHI A;  3WCB A;  3LEE A;  4LIX A;  3KRA A;  1V4K A;  4NFI F;  3KB9 A;  3WC9 A;  1RQJ A;  4OMG A;  4OKM A;  4JZB A;  2OPN A;  3ASX A;  5JV0 F;  1YHL A;  2AEK A;  3CP6 A;  1V4E A;  3ACX A;  5B01 A;  5B00 A;  3ICM A;  1HXG A;  2AET A;  5HN8 A;  3Q2Q A;  1RTR A;  1UBV A;  4HD1 A;  2QIS A;  3N0F A;  3ICN A;  3KRP B;  3QQV A;  4XQT F;  2OA6 A;  4RXC A;  3WCF A;  2Z50 A;  4E9Z A;  2Z7I A;  4F6X A;  5IMI A;  5IMN A;  3ICK A;  3TFV A;  2ONG A;  5E8L A;  3N3L F;  3WE9 A;  4LZ3 A;  2E91 A;  4E9U A;  2VF6 A;  3PDE A;  4DWG A;  1YYQ A;  5IK9 A;  2PS4 A;  1DI1 A;  2Z4Z A;  2Z4X A;  2J1P A;  3IBA A;  3DYG A;  3VJ9 A;  5IKA A;  3EZ3 A;  5HN9 A;  4KWD A;  1JFG A;  4RYP A;  4LUU A;  5CG6 A;  1UBW A;  4UMJ A;  3LK5 A;  3G4D A;  4KVD A;  5ERO A;  5I1U A;  3KRF A;  4DZW A;  3QKC A;  5AEL A;  2F9K F;  2H8O A;  1N21 A;  1WL2 A;  5E8K A;  5ERM A;  2P1C A;  3UCA A;  3V1X A;  3SAE A;  4DWB A;  3P8R A;  5DGS F;  4OKZ A;  3WEG A;  4KQS A;  3LDW A;  3RBM A;  3SDT A;  1UBY A;  2Z7H A;  5B0J A;  1YQ7 A;  2F89 F;  3KRA B;  2Q80 A;  4F6V A;  2AZK A;  5HNA A;  5DGN F;  4LA6 A;  3LVS A;  4KK2 A;  2ZY1 A;  4OGU A;  3OYR A;  5AYP A;  3WCD A;  4LTV A;  5DJV F;  1N20 A;  3N1V F;  4DEM F;  4DXJ A;  3N5J F;  4LZ0 A;  3M02 A; 
#chains in the Genus database with same CATH homology
 1N24 A;  4FJQ A;  3N46 F;  4KPJ A;  3RMG A;  3LOM A;  2Q9Z A;  4H5D F;  1WL0 A;  4F62 A;  4ZQ8 A;  2ZEU A;  3ID0 A;  5IL8 A;  5IKH A;  3N0G A;  3WCL A;  3WCJ A;  1KIZ A;  1V4J A;  2ZCS A;  4NFJ F;  4P0X A;  5EAU A;  1VG4 A;  1EZF A;  2E92 A;  3N1W F;  3TFN A;  4QPF A;  4DI5 A;  3WEJ A;  2Q58 A;  2Z4Y A;  3PH7 A;  5DZ2 A;  1WY0 A;  3RYE A;  5IK6 A;  4LPH F;  1FPS A;  2Z78 A;  3AE0 A;  3WEF A;  3M00 A;  3NPK A;  4N1Z F;  5ILI A;  3MAV A;  3CKE A;  4H5C F;  2PS6 A;  3G4F A;  2E93 A;  1HXC A;  4LFE A;  3KRF B;  5ILZ A;  3MZV A;  5B02 A;  3IPI A;  3AQB B;  4KVW A;  2F94 F;  5EAS A;  2PS5 A;  5AFX A;  1PS1 A;  3KRO A;  3AQ0 A;  4XQS F;  3VJB A;  4N9U A;  3NF2 A;  2O1O A;  5DJR F;  2PS7 A;  4H5E F;  1V4H A;  1WMW A;  2Z4V A;  3P41 A;  3Q1O A;  4LFG A;  1YHK A;  2ZCR A;  1VG7 A;  5A0J A;  5DIQ F;  2J5C A;  3WCC A;  5ILH A;  4MC0 A;  4JXN A;  3S9V A;  2E8W A;  3N3D A;  4JYX A;  4DHD A;  5JUZ F;  4FP4 A;  3KRC A;  3V1V A;  3ACY A;  4KFA A;  2ZCO A;  4EA2 A;  3SDQ A;  3OAC A;  3TFP A;  3OAB A;  3TS7 A;  4K10 A;  4MC8 A;  3Q30 A;  4NFK F;  3S4J A;  3ZCD A;  4KVI A;  3ADZ A;  3ZMB A;  4LPG F;  4LOB A;  3ZL6 A;  4E1E A;  5A0I A;  3BNX A;  3PKO A;  4JVJ F;  4NUA A;  2DH4 A;  3EGT A;  4QXS F;  1UBX A;  5DW7 A;  4KQU A;  4OMH A;  4P0W A;  2Z52 A;  1KIY A;  3NRI A;  1HXA A;  4GAX A;  1YYS A;  3WCG A;  3SDU A;  4GA3 A;  1WL1 A;  3WEI A;  4P0V A;  1RQI A;  4RXA A;  5IVG A;  4LA5 A;  3DYH A;  3CC9 A;  5ILY A;  2I19 A;  4XQR F;  4PVY F;  3WSA A;  4MC3 A;  3LMD A;  5DJP F;  1YHM A;  4Q23 A;  3VJE A;  2E90 A;  3ZMC A;  4KQ5 A;  1DGP A;  2AEL A;  4LLT A;  4EA1 A;  3KRO B;  5E8H A;  3VJA A;  2ZEV A;  3ICZ A;  5B03 A;  5B0K A;  4NG6 A;  2ZCQ A;  3WJK A;  3M9U A;  1N23 A;  3WSB A;  1ZW5 A;  3WCM A;  3LGK A;  4LXW A;  1VG3 A;  3AQC B;  1YJ4 A;  3P8L A;  3PYA A;  2F8C F;  3LLW A;  4NKF A;  3TC1 A;  2E94 A;  5B0L A;  2F7M F;  3KRC B;  4JZX A;  5IN8 A;  3W7F A;  3OAC B;  2E8V A;  3OAB B;  4EA0 A;  5DGM F;  3P5P A;  4GP1 A;  1YYT A;  1N22 A;  5HN7 A;  4RXE A;  4KPD A;  3WEK A;  2J1O A;  3LGZ B;  5DHK A;  4JXY A;  3VJ8 A;  3M0G A;  5IMP A;  3WEH A;  2E4O A;  3Q2Z A;  2AZL A;  1V4I A;  3DYF A;  2ONH A;  2E8X A;  4KUX A;  3BNY A;  4RXD A;  5IK0 A;  2FTZ A;  4PVX F;  5JV2 F;  3WCE A;  1YYR A;  2F8Z F;  5ILK A;  3N45 F;  2E8U A;  2AZJ A;  3B7L A;  1N1Z A;  2E8T A;  3KBK A;  3SDV A;  4WK5 A;  3RYW A;  5ER8 A;  3EFQ A;  2EWG A;  5ILJ A;  3KRP A;  5ILD A;  4L2X F;  1HM4 A;  3ACW A;  1HM7 A;  1WL3 A;  2OGD A;  4LFV F;  3WCA A;  3V66 A;  5IM1 A;  3VJC A;  2OPM A;  5AHU B;  5B0M A;  2Q9Y A;  5H9D A;  2RAH A;  4LLS A;  3WCI A;  1VG2 A;  3APZ A;  3ZOU A;  5ERN A;  2Z4W A;  4KKM A;  3N5H F;  4LZC A;  4RNQ A;  2F92 F;  2FOR A;  4LTZ A;  3LG5 A;  3LZ9 A;  2PS8 A;  3PYB A;  4KVY A;  5C05 A;  3LSN A;  3WJO A;  1YV5 A;  3VJD A;  3LJI A;  3SDR A;  5A0K A;  5JA0 F;  5B0I A;  4GP2 A;  5JV1 F;  1HX9 A;  3WJN A;  1WKZ A;  5CG5 A;  3N49 F;  5IL3 A;  3NPR A;  3WCH A;  5KSX F;  4NKE A;  3M01 A;  1YYU A;  3P5R A;  1N1B A;  3N6K F;  2E95 A;  1JFA A;  1VG6 A;  5EAT A;  5DHI A;  3WCB A;  3LEE A;  4LIX A;  3KRA A;  1V4K A;  4NFI F;  3KB9 A;  3WC9 A;  1RQJ A;  4OMG A;  4OKM A;  4JZB A;  2OPN A;  3ASX A;  5JV0 F;  1YHL A;  2AEK A;  3CP6 A;  1V4E A;  3ACX A;  5B01 A;  5B00 A;  3ICM A;  1HXG A;  2AET A;  5HN8 A;  3Q2Q A;  1RTR A;  1UBV A;  4HD1 A;  2QIS A;  3N0F A;  3ICN A;  3KRP B;  3QQV A;  4XQT F;  2OA6 A;  4RXC A;  3WCF A;  2Z50 A;  4E9Z A;  2Z7I A;  4F6X A;  5IMI A;  5IMN A;  3ICK A;  3TFV A;  2ONG A;  5E8L A;  3N3L F;  3WE9 A;  4LZ3 A;  2E91 A;  4E9U A;  2VF6 A;  3PDE A;  4DWG A;  1YYQ A;  5IK9 A;  2PS4 A;  1DI1 A;  2Z4Z A;  2Z4X A;  2J1P A;  3IBA A;  3DYG A;  3VJ9 A;  5IKA A;  3EZ3 A;  5HN9 A;  4KWD A;  1JFG A;  4RYP A;  4LUU A;  5CG6 A;  1UBW A;  4UMJ A;  3LK5 A;  3G4D A;  4KVD A;  5ERO A;  5I1U A;  3KRF A;  4DZW A;  3QKC A;  5AEL A;  2F9K F;  2H8O A;  1N21 A;  1WL2 A;  5E8K A;  5ERM A;  2P1C A;  3UCA A;  3V1X A;  3SAE A;  4DWB A;  3P8R A;  5DGS F;  4OKZ A;  3WEG A;  4KQS A;  3LDW A;  3RBM A;  3SDT A;  1UBY A;  2Z7H A;  5B0J A;  1YQ7 A;  2F89 F;  3KRA B;  2Q80 A;  4F6V A;  2AZK A;  5HNA A;  5DGN F;  4LA6 A;  3LVS A;  4KK2 A;  2ZY1 A;  4OGU A;  3OYR A;  5AYP A;  3WCD A;  4LTV A;  5DJV F;  1N20 A;  3N1V F;  4DEM F;  4DXJ A;  3N5J F;  4LZ0 A;  3M02 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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