5DJRF

Crystal structure of human fpps in complex with biaryl compound 6
Total Genus 135
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
135
sequence length
342
structure length
342
Chain Sequence
VYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Farnesyl pyrophosphate synthase
publication title Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 135
structure length 342
sequence length 342
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2015-09-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 5djrF00
5JV1F 3VJEA 4LTZA 4LUUA 5B0MA 5EROA 3CKEA 2F8CF 1HX9A 1UBVA 5IK9A 3VJBA 1N24A 4RNQA 3WCIA 4KVWA 3M02A 5ILKA 1HXAA 2Z7HA 1YV5A 1YYTA 2Q9ZA 1YHMA 2P1CA 3ID0A 3AQBB 5IL3A 5JV2F 3ACWA 2AETA 2PS5A 3WSBA 4JVJF 3WCAA 4UMJA 4H5DF 3SDVA 3NRIA 3LOMA 3EGTA 2VF6A 5B0LA 3DYFA 4JXYA 2J5CA 5AFXA 3RYWA 1FPSA 1RQJA 3TFNA 4XQTF 3NPRA 3VJDA 5IL8A 5IK0A 4LOBA 5DJVF 1YYRA 4GAXA 4E1EA 5B03A 5CG6A 3WCFA 5IN8A 2Q58A 2F7MF 1YYQA 4LZ3A 5IK6A 3LGZB 4KVIA 2QISA 4DWGA 3Q30A 3BNXA 4H5EF 4JZXA 5AHUB 4F6VA 4WK5A 4DHDA 3NPKA 3N0FA 3DYGA 1RQIA 3RYEA 5A0IA 3WEFA 3ICMA 5IKAA 2OA6A 4KFAA 4LZ0A 4L2XF 1N22A 4P0VA 5EASA 5IMIA 1JFAA 1N23A 3AQCB 4KVYA 2PS4A 2Z4ZA 4NUAA 3AE0A 3SAEA 2F9KF 3VJ8A 3KROB 4QPFA 5IM1A 2H8OA 2Q80A 5JV0F 4GP1A 1HXGA 4KKMA 3N46F 2Q9YA 3LG5A 5IMNA 4MC8A 3P5PA 3MAVA 4XQSF 5IMPA 5ER8A 3N0GA 2E90A 5DW7A 3RMGA 3VJ9A 1YHKA 5ILYA 3KB9A 5EATA 1UBYA 3WCBA 2F92F 3PYAA 3WCJA 1WY0A 4LPGF 3KRFA 3UCAA 5DHKA 3KRCB 3V66A 4EA1A 2PS8A 5B02A 3WJKA 4KVDA 4RXCA 2F89F 3VJCA 2ZCOA 2AELA 4KK2A 1V4IA 3ZCDA 4KWDA 3G4DA 5E8HA 4NFKF 3S9VA 2FORA 2OPNA 4LFGA 4PVYF 3M01A 4JYXA 3ACXA 3TC1A 3WEGA 3OACB 4K10A 4P0WA 5DJRF 1N1BA 4KQSA 2ZEUA 4F62A 1ZW5A 4E9ZA 3KRPB 3OABA 4GA3A 3M00A 3PKOA 3LK5A 2ZEVA 2AZJA 3WSAA 4KPJA 3N45F 3ICNA 4RXAA 3ACYA 3KRAA 4FJQA 4LLSA 4PVXF 5ERNA 2ZCQA 1VG7A 2E8VA 4DWBA 3Q2QA 5ILJA 2RAHA 4EA0A 1YYSA 3LVSA 3IBAA 4LLTA 3CC9A 4N9UA 2ONHA 3N3LF 4RXEA 5DGMF 5HNAA 5ERMA 3WCDA 3KBKA 1HM4A 1HM7A 3SDUA 4LFEA 4HD1A 4P0XA 2O1OA 2PS7A 4N1ZF 3IPIA 5B0JA 3WCLA 2PS6A 2E8WA 4OMHA 3EZ3A 3WEJA 3ZL6A 2Z4WA 5DIQF 3BNYA 2OPMA 3WEIA 3W7FA 2I19A 3PYBA 3QKCA 3SDRA 3KRCA 3WCHA 1WL3A 4XQRF 4LIXA 5B00A 2ZCRA 3WEHA 3N49F 1VG4A 5DHIA 5EAUA 3WCCA 1V4JA 3ADZA 2E91A 3LDWA 4LZCA 3WCGA 4JXNA 4EA2A 4OGUA 2E94A 3LJIA 1YHLA 1N21A 1KIYA 3ZMCA 4Q23A 2F8ZF 1WL2A 4DXJA 4OKZA 3P8LA 3LSNA 3SDTA 2E92A 2AEKA 4NFJF 4NFIF 3N5HF 3WC9A 5HN8A 4NG6A 2DH4A 4DI5A 3WCEA 2E4OA 3ASXA 3CP6A 3PDEA 3V1VA 4LFVF 3ICZA 4RXDA 3S4JA 5ILHA 3TFPA 5ILDA 5ILIA 2F94F 5I1UA 3WE9A 3LZ9A 5DZ2A 3WJNA 4NKEA 5E8KA 4KQ5A 1UBWA 3M9UA 5E8LA 4OKMA 5B0KA 4OMGA 3LMDA 2ZCSA 2Z52A 5A0JA 3M0GA 3KRFB 3N5JF 5JA0F 2OGDA 3LEEA 4KUXA 3RBMA 1EZFA 3DYHA 1HXCA 3V1XA 4F6XA 3P5RA 3OYRA 4LTVA 5DJPF 4GP2A 2Z4YA 3WCMA 2E8TA 2ONGA 1WKZA 1V4KA 1N1ZA 3ICKA 1V4EA 1V4HA 2FTZA 3G4FA 3TFVA 4FP4A 3PH7A 5ILZA 3EFQA 5H9DA 1PS1A 3N3DA 3KROA 3QQVA 3MZVA 1YQ7A 2E93A 3NF2A 3OABB 1KIZA 5HN9A 2Z4XA 1JFGA 1N20A 1YYUA 5B01A 5DGNF 2E95A 3VJAA 2E8UA 3APZA 3Q1OA 4NKFA 5IKHA 2Z4VA 4H5CF 2J1OA 3ZOUA 3SDQA 1DI1A 1UBXA 4LXWA 4QXSF 1YJ4A 1VG3A 5IVGA 3P8RA 3LLWA 3KRAB 3LGKA 1VG6A 4KQUA 3P41A 5AELA 4LA6A 3AQ0A 4LA5A 5CG5A 2Z78A 4MC0A 4JZBA 5B0IA 4DZWA 3N1VF 4MC3A 2AZLA 2Z50A 5JUZF 2AZKA 1WL0A 2ZY1A 5HN7A 1VG2A 3N6KF 4LPHF 4E9UA 3WEKA 5DGSF 5KSXF 3ZMBA 1DGPA 3B7LA 3OACA 1WMWA 4ZQ8A 4DEMF 5AYPA 1RTRA 3Q2ZA 2J1PA 2E8XA 4RYPA 3TS7A 4KPDA 3KRPA 2Z7IA 5C05A 3N1WF 3WJOA 1WL1A 5A0KA 2EWGA
chains in the Genus database with same CATH superfamily
5JV1F 3VJEA 4LTZA 4LUUA 5B0MA 5EROA 3CKEA 2F8CF 1HX9A 1UBVA 5IK9A 3VJBA 1N24A 4RNQA 3WCIA 4KVWA 3M02A 5ILKA 1HXAA 2Z7HA 1YV5A 1YYTA 2Q9ZA 1YHMA 2P1CA 3ID0A 3AQBB 5IL3A 5JV2F 3ACWA 2AETA 2PS5A 3WSBA 4JVJF 3WCAA 4UMJA 4H5DF 3SDVA 3NRIA 3LOMA 3EGTA 2VF6A 5B0LA 3DYFA 4JXYA 2J5CA 5AFXA 3RYWA 1FPSA 1RQJA 3TFNA 4XQTF 3NPRA 3VJDA 5IL8A 5IK0A 4LOBA 5DJVF 1YYRA 4GAXA 4E1EA 5B03A 5CG6A 3WCFA 5IN8A 2Q58A 2F7MF 1YYQA 4LZ3A 5IK6A 3LGZB 4KVIA 2QISA 4DWGA 3Q30A 3BNXA 4H5EF 4JZXA 5AHUB 4F6VA 4WK5A 4DHDA 3NPKA 3N0FA 3DYGA 1RQIA 3RYEA 5A0IA 3WEFA 3ICMA 5IKAA 2OA6A 4KFAA 4LZ0A 4L2XF 1N22A 4P0VA 5EASA 5IMIA 1JFAA 1N23A 3AQCB 4KVYA 2PS4A 2Z4ZA 4NUAA 3AE0A 3SAEA 2F9KF 3VJ8A 3KROB 4QPFA 5IM1A 2H8OA 2Q80A 5JV0F 4GP1A 1HXGA 4KKMA 3N46F 2Q9YA 3LG5A 5IMNA 4MC8A 3P5PA 3MAVA 4XQSF 5IMPA 5ER8A 3N0GA 2E90A 5DW7A 3RMGA 3VJ9A 1YHKA 5ILYA 3KB9A 5EATA 1UBYA 3WCBA 2F92F 3PYAA 3WCJA 1WY0A 4LPGF 3KRFA 3UCAA 5DHKA 3KRCB 3V66A 4EA1A 2PS8A 5B02A 3WJKA 4KVDA 4RXCA 2F89F 3VJCA 2ZCOA 2AELA 4KK2A 1V4IA 3ZCDA 4KWDA 3G4DA 5E8HA 4NFKF 3S9VA 2FORA 2OPNA 4LFGA 4PVYF 3M01A 4JYXA 3ACXA 3TC1A 3WEGA 3OACB 4K10A 4P0WA 5DJRF 1N1BA 4KQSA 2ZEUA 4F62A 1ZW5A 4E9ZA 3KRPB 3OABA 4GA3A 3M00A 3PKOA 3LK5A 2ZEVA 2AZJA 3WSAA 4KPJA 3N45F 3ICNA 4RXAA 3ACYA 3KRAA 4FJQA 4LLSA 4PVXF 5ERNA 2ZCQA 1VG7A 2E8VA 4DWBA 3Q2QA 5ILJA 2RAHA 4EA0A 1YYSA 3LVSA 3IBAA 4LLTA 3CC9A 4N9UA 2ONHA 3N3LF 4RXEA 5DGMF 5HNAA 5ERMA 3WCDA 3KBKA 1HM4A 1HM7A 3SDUA 4LFEA 4HD1A 4P0XA 2O1OA 2PS7A 4N1ZF 3IPIA 5B0JA 3WCLA 2PS6A 2E8WA 4OMHA 3EZ3A 3WEJA 3ZL6A 2Z4WA 5DIQF 3BNYA 2OPMA 3WEIA 3W7FA 2I19A 3PYBA 3QKCA 3SDRA 3KRCA 3WCHA 1WL3A 4XQRF 4LIXA 5B00A 2ZCRA 3WEHA 3N49F 1VG4A 5DHIA 5EAUA 3WCCA 1V4JA 3ADZA 2E91A 3LDWA 4LZCA 3WCGA 4JXNA 4EA2A 4OGUA 2E94A 3LJIA 1YHLA 1N21A 1KIYA 3ZMCA 4Q23A 2F8ZF 1WL2A 4DXJA 4OKZA 3P8LA 3LSNA 3SDTA 2E92A 2AEKA 4NFJF 4NFIF 3N5HF 3WC9A 5HN8A 4NG6A 2DH4A 4DI5A 3WCEA 2E4OA 3ASXA 3CP6A 3PDEA 3V1VA 4LFVF 3ICZA 4RXDA 3S4JA 5ILHA 3TFPA 5ILDA 5ILIA 2F94F 5I1UA 3WE9A 3LZ9A 5DZ2A 3WJNA 4NKEA 5E8KA 4KQ5A 1UBWA 3M9UA 5E8LA 4OKMA 5B0KA 4OMGA 3LMDA 2ZCSA 2Z52A 5A0JA 3M0GA 3KRFB 3N5JF 5JA0F 2OGDA 3LEEA 4KUXA 3RBMA 1EZFA 3DYHA 1HXCA 3V1XA 4F6XA 3P5RA 3OYRA 4LTVA 5DJPF 4GP2A 2Z4YA 3WCMA 2E8TA 2ONGA 1WKZA 1V4KA 1N1ZA 3ICKA 1V4EA 1V4HA 2FTZA 3G4FA 3TFVA 4FP4A 3PH7A 5ILZA 3EFQA 5H9DA 1PS1A 3N3DA 3KROA 3QQVA 3MZVA 1YQ7A 2E93A 3NF2A 3OABB 1KIZA 5HN9A 2Z4XA 1JFGA 1N20A 1YYUA 5B01A 5DGNF 2E95A 3VJAA 2E8UA 3APZA 3Q1OA 4NKFA 5IKHA 2Z4VA 4H5CF 2J1OA 3ZOUA 3SDQA 1DI1A 1UBXA 4LXWA 4QXSF 1YJ4A 1VG3A 5IVGA 3P8RA 3LLWA 3KRAB 3LGKA 1VG6A 4KQUA 3P41A 5AELA 4LA6A 3AQ0A 4LA5A 5CG5A 2Z78A 4MC0A 4JZBA 5B0IA 4DZWA 3N1VF 4MC3A 2AZLA 2Z50A 5JUZF 2AZKA 1WL0A 2ZY1A 5HN7A 1VG2A 3N6KF 4LPHF 4E9UA 3WEKA 5DGSF 5KSXF 3ZMBA 1DGPA 3B7LA 3OACA 1WMWA 4ZQ8A 4DEMF 5AYPA 1RTRA 3Q2ZA 2J1PA 2E8XA 4RYPA 3TS7A 4KPDA 3KRPA 2Z7IA 5C05A 3N1WF 3WJOA 1WL1A 5A0KA 2EWGA
chains in the Genus database with same CATH topology
5JV1F 3VJEA 4LTZA 4LUUA 5B0MA 5EROA 3CKEA 2F8CF 1HX9A 1UBVA 5IK9A 3VJBA 1N24A 4RNQA 3WCIA 4KVWA 3M02A 5ILKA 1HXAA 2Z7HA 1YV5A 1YYTA 2Q9ZA 1YHMA 2P1CA 3ID0A 3AQBB 5IL3A 5JV2F 3ACWA 2AETA 2PS5A 3WSBA 4JVJF 3WCAA 4UMJA 4H5DF 3SDVA 3NRIA 3LOMA 3EGTA 2VF6A 5B0LA 3DYFA 4JXYA 2J5CA 5AFXA 3RYWA 1FPSA 1RQJA 3TFNA 4XQTF 3NPRA 3VJDA 5IL8A 5IK0A 4LOBA 5DJVF 1YYRA 4GAXA 4E1EA 5B03A 5CG6A 3WCFA 5IN8A 2Q58A 2F7MF 1YYQA 4LZ3A 5IK6A 3LGZB 4KVIA 2QISA 4DWGA 3Q30A 3BNXA 4H5EF 4JZXA 5AHUB 4F6VA 4WK5A 4DHDA 3NPKA 3N0FA 3DYGA 1RQIA 3RYEA 5A0IA 3WEFA 3ICMA 5IKAA 2OA6A 4KFAA 4LZ0A 4L2XF 1N22A 4P0VA 5EASA 5IMIA 1JFAA 1N23A 3AQCB 4KVYA 2PS4A 2Z4ZA 4NUAA 3AE0A 3SAEA 2F9KF 3VJ8A 3KROB 4QPFA 5IM1A 2H8OA 2Q80A 5JV0F 4GP1A 1HXGA 4KKMA 3N46F 2Q9YA 3LG5A 5IMNA 4MC8A 3P5PA 3MAVA 4XQSF 5IMPA 5ER8A 3N0GA 2E90A 5DW7A 3RMGA 3VJ9A 1YHKA 5ILYA 3KB9A 5EATA 1UBYA 3WCBA 2F92F 3PYAA 3WCJA 1WY0A 4LPGF 3KRFA 3UCAA 5DHKA 3KRCB 3V66A 4EA1A 2PS8A 5B02A 3WJKA 4KVDA 4RXCA 2F89F 3VJCA 2ZCOA 2AELA 4KK2A 1V4IA 3ZCDA 4KWDA 3G4DA 5E8HA 4NFKF 3S9VA 2FORA 2OPNA 4LFGA 4PVYF 3M01A 4JYXA 3ACXA 3TC1A 3WEGA 3OACB 4K10A 4P0WA 5DJRF 1N1BA 4KQSA 2ZEUA 4F62A 1ZW5A 4E9ZA 3KRPB 3OABA 4GA3A 3M00A 3PKOA 3LK5A 2ZEVA 2AZJA 3WSAA 4KPJA 3N45F 3ICNA 4RXAA 3ACYA 3KRAA 4FJQA 4LLSA 4PVXF 5ERNA 2ZCQA 1VG7A 2E8VA 4DWBA 3Q2QA 5ILJA 2RAHA 4EA0A 1YYSA 3LVSA 3IBAA 4LLTA 3CC9A 4N9UA 2ONHA 3N3LF 4RXEA 5DGMF 5HNAA 5ERMA 3WCDA 3KBKA 1HM4A 1HM7A 3SDUA 4LFEA 4HD1A 4P0XA 2O1OA 2PS7A 4N1ZF 3IPIA 5B0JA 3WCLA 2PS6A 2E8WA 4OMHA 3EZ3A 3WEJA 3ZL6A 2Z4WA 5DIQF 3BNYA 2OPMA 3WEIA 3W7FA 2I19A 3PYBA 3QKCA 3SDRA 3KRCA 3WCHA 1WL3A 4XQRF 4LIXA 5B00A 2ZCRA 3WEHA 3N49F 1VG4A 5DHIA 5EAUA 3WCCA 1V4JA 3ADZA 2E91A 3LDWA 4LZCA 3WCGA 4JXNA 4EA2A 4OGUA 2E94A 3LJIA 1YHLA 1N21A 1KIYA 3ZMCA 4Q23A 2F8ZF 1WL2A 4DXJA 4OKZA 3P8LA 3LSNA 3SDTA 2E92A 2AEKA 4NFJF 4NFIF 3N5HF 3WC9A 5HN8A 4NG6A 2DH4A 4DI5A 3WCEA 2E4OA 3ASXA 3CP6A 3PDEA 3V1VA 4LFVF 3ICZA 4RXDA 3S4JA 5ILHA 3TFPA 5ILDA 5ILIA 2F94F 5I1UA 3WE9A 3LZ9A 5DZ2A 3WJNA 4NKEA 5E8KA 4KQ5A 1UBWA 3M9UA 5E8LA 4OKMA 5B0KA 4OMGA 3LMDA 2ZCSA 2Z52A 5A0JA 3M0GA 3KRFB 3N5JF 5JA0F 2OGDA 3LEEA 4KUXA 3RBMA 1EZFA 3DYHA 1HXCA 3V1XA 4F6XA 3P5RA 3OYRA 4LTVA 5DJPF 4GP2A 2Z4YA 3WCMA 2E8TA 2ONGA 1WKZA 1V4KA 1N1ZA 3ICKA 1V4EA 1V4HA 2FTZA 3G4FA 3TFVA 4FP4A 3PH7A 5ILZA 3EFQA 5H9DA 1PS1A 3N3DA 3KROA 3QQVA 3MZVA 1YQ7A 2E93A 3NF2A 3OABB 1KIZA 5HN9A 2Z4XA 1JFGA 1N20A 1YYUA 5B01A 5DGNF 2E95A 3VJAA 2E8UA 3APZA 3Q1OA 4NKFA 5IKHA 2Z4VA 4H5CF 2J1OA 3ZOUA 3SDQA 1DI1A 1UBXA 4LXWA 4QXSF 1YJ4A 1VG3A 5IVGA 3P8RA 3LLWA 3KRAB 3LGKA 1VG6A 4KQUA 3P41A 5AELA 4LA6A 3AQ0A 4LA5A 5CG5A 2Z78A 4MC0A 4JZBA 5B0IA 4DZWA 3N1VF 4MC3A 2AZLA 2Z50A 5JUZF 2AZKA 1WL0A 2ZY1A 5HN7A 1VG2A 3N6KF 4LPHF 4E9UA 3WEKA 5DGSF 5KSXF 3ZMBA 1DGPA 3B7LA 3OACA 1WMWA 4ZQ8A 4DEMF 5AYPA 1RTRA 3Q2ZA 2J1PA 2E8XA 4RYPA 3TS7A 4KPDA 3KRPA 2Z7IA 5C05A 3N1WF 3WJOA 1WL1A 5A0KA 2EWGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5JV1 F;  3VJE A;  4LTZ A;  4LUU A;  5B0M A;  5ERO A;  3CKE A;  2F8C F;  1HX9 A;  1UBV A;  5IK9 A;  3VJB A;  1N24 A;  4RNQ A;  3WCI A;  4KVW A;  3M02 A;  5ILK A;  1HXA A;  2Z7H A;  1YV5 A;  1YYT A;  2Q9Z A;  1YHM A;  2P1C A;  3ID0 A;  3AQB B;  5IL3 A;  5JV2 F;  3ACW A;  2AET A;  2PS5 A;  3WSB A;  4JVJ F;  3WCA A;  4UMJ A;  4H5D F;  3SDV A;  3NRI A;  3LOM A;  3EGT A;  2VF6 A;  5B0L A;  3DYF A;  4JXY A;  2J5C A;  5AFX A;  3RYW A;  1FPS A;  1RQJ A;  3TFN A;  4XQT F;  3NPR A;  3VJD A;  5IL8 A;  5IK0 A;  4LOB A;  5DJV F;  1YYR A;  4GAX A;  4E1E A;  5B03 A;  5CG6 A;  3WCF A;  5IN8 A;  2Q58 A;  2F7M F;  1YYQ A;  4LZ3 A;  5IK6 A;  3LGZ B;  4KVI A;  2QIS A;  4DWG A;  3Q30 A;  3BNX A;  4H5E F;  4JZX A;  5AHU B;  4F6V A;  4WK5 A;  4DHD A;  3NPK A;  3N0F A;  3DYG A;  1RQI A;  3RYE A;  5A0I A;  3WEF A;  3ICM A;  5IKA A;  2OA6 A;  4KFA A;  4LZ0 A;  4L2X F;  1N22 A;  4P0V A;  5EAS A;  5IMI A;  1JFA A;  1N23 A;  3AQC B;  4KVY A;  2PS4 A;  2Z4Z A;  4NUA A;  3AE0 A;  3SAE A;  2F9K F;  3VJ8 A;  3KRO B;  4QPF A;  5IM1 A;  2H8O A;  2Q80 A;  5JV0 F;  4GP1 A;  1HXG A;  4KKM A;  3N46 F;  2Q9Y A;  3LG5 A;  5IMN A;  4MC8 A;  3P5P A;  3MAV A;  4XQS F;  5IMP A;  5ER8 A;  3N0G A;  2E90 A;  5DW7 A;  3RMG A;  3VJ9 A;  1YHK A;  5ILY A;  3KB9 A;  5EAT A;  1UBY A;  3WCB A;  2F92 F;  3PYA A;  3WCJ A;  1WY0 A;  4LPG F;  3KRF A;  3UCA A;  5DHK A;  3KRC B;  3V66 A;  4EA1 A;  2PS8 A;  5B02 A;  3WJK A;  4KVD A;  4RXC A;  2F89 F;  3VJC A;  2ZCO A;  2AEL A;  4KK2 A;  1V4I A;  3ZCD A;  4KWD A;  3G4D A;  5E8H A;  4NFK F;  3S9V A;  2FOR A;  2OPN A;  4LFG A;  4PVY F;  3M01 A;  4JYX A;  3ACX A;  3TC1 A;  3WEG A;  3OAC B;  4K10 A;  4P0W A;  5DJR F;  1N1B A;  4KQS A;  2ZEU A;  4F62 A;  1ZW5 A;  4E9Z A;  3KRP B;  3OAB A;  4GA3 A;  3M00 A;  3PKO A;  3LK5 A;  2ZEV A;  2AZJ A;  3WSA A;  4KPJ A;  3N45 F;  3ICN A;  4RXA A;  3ACY A;  3KRA A;  4FJQ A;  4LLS A;  4PVX F;  5ERN A;  2ZCQ A;  1VG7 A;  2E8V A;  4DWB A;  3Q2Q A;  5ILJ A;  2RAH A;  4EA0 A;  1YYS A;  3LVS A;  3IBA A;  4LLT A;  3CC9 A;  4N9U A;  2ONH A;  3N3L F;  4RXE A;  5DGM F;  5HNA A;  5ERM A;  3WCD A;  3KBK A;  1HM4 A;  1HM7 A;  3SDU A;  4LFE A;  4HD1 A;  4P0X A;  2O1O A;  2PS7 A;  4N1Z F;  3IPI A;  5B0J A;  3WCL A;  2PS6 A;  2E8W A;  4OMH A;  3EZ3 A;  3WEJ A;  3ZL6 A;  2Z4W A;  5DIQ F;  3BNY A;  2OPM A;  3WEI A;  3W7F A;  2I19 A;  3PYB A;  3QKC A;  3SDR A;  3KRC A;  3WCH A;  1WL3 A;  4XQR F;  4LIX A;  5B00 A;  2ZCR A;  3WEH A;  3N49 F;  1VG4 A;  5DHI A;  5EAU A;  3WCC A;  1V4J A;  3ADZ A;  2E91 A;  3LDW A;  4LZC A;  3WCG A;  4JXN A;  4EA2 A;  4OGU A;  2E94 A;  3LJI A;  1YHL A;  1N21 A;  1KIY A;  3ZMC A;  4Q23 A;  2F8Z F;  1WL2 A;  4DXJ A;  4OKZ A;  3P8L A;  3LSN A;  3SDT A;  2E92 A;  2AEK A;  4NFJ F;  4NFI F;  3N5H F;  3WC9 A;  5HN8 A;  4NG6 A;  2DH4 A;  4DI5 A;  3WCE A;  2E4O A;  3ASX A;  3CP6 A;  3PDE A;  3V1V A;  4LFV F;  3ICZ A;  4RXD A;  3S4J A;  5ILH A;  3TFP A;  5ILD A;  5ILI A;  2F94 F;  5I1U A;  3WE9 A;  3LZ9 A;  5DZ2 A;  3WJN A;  4NKE A;  5E8K A;  4KQ5 A;  1UBW A;  3M9U A;  5E8L A;  4OKM A;  5B0K A;  4OMG A;  3LMD A;  2ZCS A;  2Z52 A;  5A0J A;  3M0G A;  3KRF B;  3N5J F;  5JA0 F;  2OGD A;  3LEE A;  4KUX A;  3RBM A;  1EZF A;  3DYH A;  1HXC A;  3V1X A;  4F6X A;  3P5R A;  3OYR A;  4LTV A;  5DJP F;  4GP2 A;  2Z4Y A;  3WCM A;  2E8T A;  2ONG A;  1WKZ A;  1V4K A;  1N1Z A;  3ICK A;  1V4E A;  1V4H A;  2FTZ A;  3G4F A;  3TFV A;  4FP4 A;  3PH7 A;  5ILZ A;  3EFQ A;  5H9D A;  1PS1 A;  3N3D A;  3KRO A;  3QQV A;  3MZV A;  1YQ7 A;  2E93 A;  3NF2 A;  3OAB B;  1KIZ A;  5HN9 A;  2Z4X A;  1JFG A;  1N20 A;  1YYU A;  5B01 A;  5DGN F;  2E95 A;  3VJA A;  2E8U A;  3APZ A;  3Q1O A;  4NKF A;  5IKH A;  2Z4V A;  4H5C F;  2J1O A;  3ZOU A;  3SDQ A;  1DI1 A;  1UBX A;  4LXW A;  4QXS F;  1YJ4 A;  1VG3 A;  5IVG A;  3P8R A;  3LLW A;  3KRA B;  3LGK A;  1VG6 A;  4KQU A;  3P41 A;  5AEL A;  4LA6 A;  3AQ0 A;  4LA5 A;  5CG5 A;  2Z78 A;  4MC0 A;  4JZB A;  5B0I A;  4DZW A;  3N1V F;  4MC3 A;  2AZL A;  2Z50 A;  5JUZ F;  2AZK A;  1WL0 A;  2ZY1 A;  5HN7 A;  1VG2 A;  3N6K F;  4LPH F;  4E9U A;  3WEK A;  5DGS F;  5KSX F;  3ZMB A;  1DGP A;  3B7L A;  3OAC A;  1WMW A;  4ZQ8 A;  4DEM F;  5AYP A;  1RTR A;  3Q2Z A;  2J1P A;  2E8X A;  4RYP A;  3TS7 A;  4KPD A;  3KRP A;  2Z7I A;  5C05 A;  3N1W F;  3WJO A;  1WL1 A;  5A0K A;  2EWG A; 
#chains in the Genus database with same CATH topology
 5JV1 F;  3VJE A;  4LTZ A;  4LUU A;  5B0M A;  5ERO A;  3CKE A;  2F8C F;  1HX9 A;  1UBV A;  5IK9 A;  3VJB A;  1N24 A;  4RNQ A;  3WCI A;  4KVW A;  3M02 A;  5ILK A;  1HXA A;  2Z7H A;  1YV5 A;  1YYT A;  2Q9Z A;  1YHM A;  2P1C A;  3ID0 A;  3AQB B;  5IL3 A;  5JV2 F;  3ACW A;  2AET A;  2PS5 A;  3WSB A;  4JVJ F;  3WCA A;  4UMJ A;  4H5D F;  3SDV A;  3NRI A;  3LOM A;  3EGT A;  2VF6 A;  5B0L A;  3DYF A;  4JXY A;  2J5C A;  5AFX A;  3RYW A;  1FPS A;  1RQJ A;  3TFN A;  4XQT F;  3NPR A;  3VJD A;  5IL8 A;  5IK0 A;  4LOB A;  5DJV F;  1YYR A;  4GAX A;  4E1E A;  5B03 A;  5CG6 A;  3WCF A;  5IN8 A;  2Q58 A;  2F7M F;  1YYQ A;  4LZ3 A;  5IK6 A;  3LGZ B;  4KVI A;  2QIS A;  4DWG A;  3Q30 A;  3BNX A;  4H5E F;  4JZX A;  5AHU B;  4F6V A;  4WK5 A;  4DHD A;  3NPK A;  3N0F A;  3DYG A;  1RQI A;  3RYE A;  5A0I A;  3WEF A;  3ICM A;  5IKA A;  2OA6 A;  4KFA A;  4LZ0 A;  4L2X F;  1N22 A;  4P0V A;  5EAS A;  5IMI A;  1JFA A;  1N23 A;  3AQC B;  4KVY A;  2PS4 A;  2Z4Z A;  4NUA A;  3AE0 A;  3SAE A;  2F9K F;  3VJ8 A;  3KRO B;  4QPF A;  5IM1 A;  2H8O A;  2Q80 A;  5JV0 F;  4GP1 A;  1HXG A;  4KKM A;  3N46 F;  2Q9Y A;  3LG5 A;  5IMN A;  4MC8 A;  3P5P A;  3MAV A;  4XQS F;  5IMP A;  5ER8 A;  3N0G A;  2E90 A;  5DW7 A;  3RMG A;  3VJ9 A;  1YHK A;  5ILY A;  3KB9 A;  5EAT A;  1UBY A;  3WCB A;  2F92 F;  3PYA A;  3WCJ A;  1WY0 A;  4LPG F;  3KRF A;  3UCA A;  5DHK A;  3KRC B;  3V66 A;  4EA1 A;  2PS8 A;  5B02 A;  3WJK A;  4KVD A;  4RXC A;  2F89 F;  3VJC A;  2ZCO A;  2AEL A;  4KK2 A;  1V4I A;  3ZCD A;  4KWD A;  3G4D A;  5E8H A;  4NFK F;  3S9V A;  2FOR A;  2OPN A;  4LFG A;  4PVY F;  3M01 A;  4JYX A;  3ACX A;  3TC1 A;  3WEG A;  3OAC B;  4K10 A;  4P0W A;  5DJR F;  1N1B A;  4KQS A;  2ZEU A;  4F62 A;  1ZW5 A;  4E9Z A;  3KRP B;  3OAB A;  4GA3 A;  3M00 A;  3PKO A;  3LK5 A;  2ZEV A;  2AZJ A;  3WSA A;  4KPJ A;  3N45 F;  3ICN A;  4RXA A;  3ACY A;  3KRA A;  4FJQ A;  4LLS A;  4PVX F;  5ERN A;  2ZCQ A;  1VG7 A;  2E8V A;  4DWB A;  3Q2Q A;  5ILJ A;  2RAH A;  4EA0 A;  1YYS A;  3LVS A;  3IBA A;  4LLT A;  3CC9 A;  4N9U A;  2ONH A;  3N3L F;  4RXE A;  5DGM F;  5HNA A;  5ERM A;  3WCD A;  3KBK A;  1HM4 A;  1HM7 A;  3SDU A;  4LFE A;  4HD1 A;  4P0X A;  2O1O A;  2PS7 A;  4N1Z F;  3IPI A;  5B0J A;  3WCL A;  2PS6 A;  2E8W A;  4OMH A;  3EZ3 A;  3WEJ A;  3ZL6 A;  2Z4W A;  5DIQ F;  3BNY A;  2OPM A;  3WEI A;  3W7F A;  2I19 A;  3PYB A;  3QKC A;  3SDR A;  3KRC A;  3WCH A;  1WL3 A;  4XQR F;  4LIX A;  5B00 A;  2ZCR A;  3WEH A;  3N49 F;  1VG4 A;  5DHI A;  5EAU A;  3WCC A;  1V4J A;  3ADZ A;  2E91 A;  3LDW A;  4LZC A;  3WCG A;  4JXN A;  4EA2 A;  4OGU A;  2E94 A;  3LJI A;  1YHL A;  1N21 A;  1KIY A;  3ZMC A;  4Q23 A;  2F8Z F;  1WL2 A;  4DXJ A;  4OKZ A;  3P8L A;  3LSN A;  3SDT A;  2E92 A;  2AEK A;  4NFJ F;  4NFI F;  3N5H F;  3WC9 A;  5HN8 A;  4NG6 A;  2DH4 A;  4DI5 A;  3WCE A;  2E4O A;  3ASX A;  3CP6 A;  3PDE A;  3V1V A;  4LFV F;  3ICZ A;  4RXD A;  3S4J A;  5ILH A;  3TFP A;  5ILD A;  5ILI A;  2F94 F;  5I1U A;  3WE9 A;  3LZ9 A;  5DZ2 A;  3WJN A;  4NKE A;  5E8K A;  4KQ5 A;  1UBW A;  3M9U A;  5E8L A;  4OKM A;  5B0K A;  4OMG A;  3LMD A;  2ZCS A;  2Z52 A;  5A0J A;  3M0G A;  3KRF B;  3N5J F;  5JA0 F;  2OGD A;  3LEE A;  4KUX A;  3RBM A;  1EZF A;  3DYH A;  1HXC A;  3V1X A;  4F6X A;  3P5R A;  3OYR A;  4LTV A;  5DJP F;  4GP2 A;  2Z4Y A;  3WCM A;  2E8T A;  2ONG A;  1WKZ A;  1V4K A;  1N1Z A;  3ICK A;  1V4E A;  1V4H A;  2FTZ A;  3G4F A;  3TFV A;  4FP4 A;  3PH7 A;  5ILZ A;  3EFQ A;  5H9D A;  1PS1 A;  3N3D A;  3KRO A;  3QQV A;  3MZV A;  1YQ7 A;  2E93 A;  3NF2 A;  3OAB B;  1KIZ A;  5HN9 A;  2Z4X A;  1JFG A;  1N20 A;  1YYU A;  5B01 A;  5DGN F;  2E95 A;  3VJA A;  2E8U A;  3APZ A;  3Q1O A;  4NKF A;  5IKH A;  2Z4V A;  4H5C F;  2J1O A;  3ZOU A;  3SDQ A;  1DI1 A;  1UBX A;  4LXW A;  4QXS F;  1YJ4 A;  1VG3 A;  5IVG A;  3P8R A;  3LLW A;  3KRA B;  3LGK A;  1VG6 A;  4KQU A;  3P41 A;  5AEL A;  4LA6 A;  3AQ0 A;  4LA5 A;  5CG5 A;  2Z78 A;  4MC0 A;  4JZB A;  5B0I A;  4DZW A;  3N1V F;  4MC3 A;  2AZL A;  2Z50 A;  5JUZ F;  2AZK A;  1WL0 A;  2ZY1 A;  5HN7 A;  1VG2 A;  3N6K F;  4LPH F;  4E9U A;  3WEK A;  5DGS F;  5KSX F;  3ZMB A;  1DGP A;  3B7L A;  3OAC A;  1WMW A;  4ZQ8 A;  4DEM F;  5AYP A;  1RTR A;  3Q2Z A;  2J1P A;  2E8X A;  4RYP A;  3TS7 A;  4KPD A;  3KRP A;  2Z7I A;  5C05 A;  3N1W F;  3WJO A;  1WL1 A;  5A0K A;  2EWG A; 
#chains in the Genus database with same CATH homology
 5JV1 F;  3VJE A;  4LTZ A;  4LUU A;  5B0M A;  5ERO A;  3CKE A;  2F8C F;  1HX9 A;  1UBV A;  5IK9 A;  3VJB A;  1N24 A;  4RNQ A;  3WCI A;  4KVW A;  3M02 A;  5ILK A;  1HXA A;  2Z7H A;  1YV5 A;  1YYT A;  2Q9Z A;  1YHM A;  2P1C A;  3ID0 A;  3AQB B;  5IL3 A;  5JV2 F;  3ACW A;  2AET A;  2PS5 A;  3WSB A;  4JVJ F;  3WCA A;  4UMJ A;  4H5D F;  3SDV A;  3NRI A;  3LOM A;  3EGT A;  2VF6 A;  5B0L A;  3DYF A;  4JXY A;  2J5C A;  5AFX A;  3RYW A;  1FPS A;  1RQJ A;  3TFN A;  4XQT F;  3NPR A;  3VJD A;  5IL8 A;  5IK0 A;  4LOB A;  5DJV F;  1YYR A;  4GAX A;  4E1E A;  5B03 A;  5CG6 A;  3WCF A;  5IN8 A;  2Q58 A;  2F7M F;  1YYQ A;  4LZ3 A;  5IK6 A;  3LGZ B;  4KVI A;  2QIS A;  4DWG A;  3Q30 A;  3BNX A;  4H5E F;  4JZX A;  5AHU B;  4F6V A;  4WK5 A;  4DHD A;  3NPK A;  3N0F A;  3DYG A;  1RQI A;  3RYE A;  5A0I A;  3WEF A;  3ICM A;  5IKA A;  2OA6 A;  4KFA A;  4LZ0 A;  4L2X F;  1N22 A;  4P0V A;  5EAS A;  5IMI A;  1JFA A;  1N23 A;  3AQC B;  4KVY A;  2PS4 A;  2Z4Z A;  4NUA A;  3AE0 A;  3SAE A;  2F9K F;  3VJ8 A;  3KRO B;  4QPF A;  5IM1 A;  2H8O A;  2Q80 A;  5JV0 F;  4GP1 A;  1HXG A;  4KKM A;  3N46 F;  2Q9Y A;  3LG5 A;  5IMN A;  4MC8 A;  3P5P A;  3MAV A;  4XQS F;  5IMP A;  5ER8 A;  3N0G A;  2E90 A;  5DW7 A;  3RMG A;  3VJ9 A;  1YHK A;  5ILY A;  3KB9 A;  5EAT A;  1UBY A;  3WCB A;  2F92 F;  3PYA A;  3WCJ A;  1WY0 A;  4LPG F;  3KRF A;  3UCA A;  5DHK A;  3KRC B;  3V66 A;  4EA1 A;  2PS8 A;  5B02 A;  3WJK A;  4KVD A;  4RXC A;  2F89 F;  3VJC A;  2ZCO A;  2AEL A;  4KK2 A;  1V4I A;  3ZCD A;  4KWD A;  3G4D A;  5E8H A;  4NFK F;  3S9V A;  2FOR A;  2OPN A;  4LFG A;  4PVY F;  3M01 A;  4JYX A;  3ACX A;  3TC1 A;  3WEG A;  3OAC B;  4K10 A;  4P0W A;  5DJR F;  1N1B A;  4KQS A;  2ZEU A;  4F62 A;  1ZW5 A;  4E9Z A;  3KRP B;  3OAB A;  4GA3 A;  3M00 A;  3PKO A;  3LK5 A;  2ZEV A;  2AZJ A;  3WSA A;  4KPJ A;  3N45 F;  3ICN A;  4RXA A;  3ACY A;  3KRA A;  4FJQ A;  4LLS A;  4PVX F;  5ERN A;  2ZCQ A;  1VG7 A;  2E8V A;  4DWB A;  3Q2Q A;  5ILJ A;  2RAH A;  4EA0 A;  1YYS A;  3LVS A;  3IBA A;  4LLT A;  3CC9 A;  4N9U A;  2ONH A;  3N3L F;  4RXE A;  5DGM F;  5HNA A;  5ERM A;  3WCD A;  3KBK A;  1HM4 A;  1HM7 A;  3SDU A;  4LFE A;  4HD1 A;  4P0X A;  2O1O A;  2PS7 A;  4N1Z F;  3IPI A;  5B0J A;  3WCL A;  2PS6 A;  2E8W A;  4OMH A;  3EZ3 A;  3WEJ A;  3ZL6 A;  2Z4W A;  5DIQ F;  3BNY A;  2OPM A;  3WEI A;  3W7F A;  2I19 A;  3PYB A;  3QKC A;  3SDR A;  3KRC A;  3WCH A;  1WL3 A;  4XQR F;  4LIX A;  5B00 A;  2ZCR A;  3WEH A;  3N49 F;  1VG4 A;  5DHI A;  5EAU A;  3WCC A;  1V4J A;  3ADZ A;  2E91 A;  3LDW A;  4LZC A;  3WCG A;  4JXN A;  4EA2 A;  4OGU A;  2E94 A;  3LJI A;  1YHL A;  1N21 A;  1KIY A;  3ZMC A;  4Q23 A;  2F8Z F;  1WL2 A;  4DXJ A;  4OKZ A;  3P8L A;  3LSN A;  3SDT A;  2E92 A;  2AEK A;  4NFJ F;  4NFI F;  3N5H F;  3WC9 A;  5HN8 A;  4NG6 A;  2DH4 A;  4DI5 A;  3WCE A;  2E4O A;  3ASX A;  3CP6 A;  3PDE A;  3V1V A;  4LFV F;  3ICZ A;  4RXD A;  3S4J A;  5ILH A;  3TFP A;  5ILD A;  5ILI A;  2F94 F;  5I1U A;  3WE9 A;  3LZ9 A;  5DZ2 A;  3WJN A;  4NKE A;  5E8K A;  4KQ5 A;  1UBW A;  3M9U A;  5E8L A;  4OKM A;  5B0K A;  4OMG A;  3LMD A;  2ZCS A;  2Z52 A;  5A0J A;  3M0G A;  3KRF B;  3N5J F;  5JA0 F;  2OGD A;  3LEE A;  4KUX A;  3RBM A;  1EZF A;  3DYH A;  1HXC A;  3V1X A;  4F6X A;  3P5R A;  3OYR A;  4LTV A;  5DJP F;  4GP2 A;  2Z4Y A;  3WCM A;  2E8T A;  2ONG A;  1WKZ A;  1V4K A;  1N1Z A;  3ICK A;  1V4E A;  1V4H A;  2FTZ A;  3G4F A;  3TFV A;  4FP4 A;  3PH7 A;  5ILZ A;  3EFQ A;  5H9D A;  1PS1 A;  3N3D A;  3KRO A;  3QQV A;  3MZV A;  1YQ7 A;  2E93 A;  3NF2 A;  3OAB B;  1KIZ A;  5HN9 A;  2Z4X A;  1JFG A;  1N20 A;  1YYU A;  5B01 A;  5DGN F;  2E95 A;  3VJA A;  2E8U A;  3APZ A;  3Q1O A;  4NKF A;  5IKH A;  2Z4V A;  4H5C F;  2J1O A;  3ZOU A;  3SDQ A;  1DI1 A;  1UBX A;  4LXW A;  4QXS F;  1YJ4 A;  1VG3 A;  5IVG A;  3P8R A;  3LLW A;  3KRA B;  3LGK A;  1VG6 A;  4KQU A;  3P41 A;  5AEL A;  4LA6 A;  3AQ0 A;  4LA5 A;  5CG5 A;  2Z78 A;  4MC0 A;  4JZB A;  5B0I A;  4DZW A;  3N1V F;  4MC3 A;  2AZL A;  2Z50 A;  5JUZ F;  2AZK A;  1WL0 A;  2ZY1 A;  5HN7 A;  1VG2 A;  3N6K F;  4LPH F;  4E9U A;  3WEK A;  5DGS F;  5KSX F;  3ZMB A;  1DGP A;  3B7L A;  3OAC A;  1WMW A;  4ZQ8 A;  4DEM F;  5AYP A;  1RTR A;  3Q2Z A;  2J1P A;  2E8X A;  4RYP A;  3TS7 A;  4KPD A;  3KRP A;  2Z7I A;  5C05 A;  3N1W F;  3WJO A;  1WL1 A;  5A0K A;  2EWG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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