5DJRF

Crystal structure of human fpps in complex with biaryl compound 6
Total Genus 135
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
135
sequence length
342
structure length
342
Chain Sequence
VYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords Farnesyl pyrophosphate synthase
publication title Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.
pubmed doi rcsb
source organism Homo sapiens
total genus 135
structure length 342
sequence length 342
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2015-09-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 5djrF00
3WCGA 5AFXA 2E8UA 3V1VA 3N6KF 4KVIA 3KRAB 3WEKA 1HM7A 1RQJA 3N1VF 3ICMA 2EWGA 4F62A 4JZBA 3N0GA 3TC1A 2VF6A 5ILZA 3N5HF 4DI5A 5B0KA 5IL3A 4PVXF 2Z4ZA 4KPJA 3UCAA 3VJEA 4GA3A 3KRPA 4RXCA 5HN9A 3QQVA 3OYRA 4E9ZA 3NRIA 3WCLA 1DI1A 5ILYA 2Z4VA 2ZEUA 3MAVA 4GP2A 5IVGA 3BNYA 5B03A 4JZXA 4KVDA 1RTRA 2AETA 4QXSF 4DWBA 3Q2ZA 5AHUB 1N20A 3ACYA 3N1WF 2QISA 3LEEA 2AZJA 5ERMA 1DGPA 4PVYF 4JXYA 3W7FA 3ACXA 3QKCA 4NKFA 4OKZA 5EAUA 2Q9ZA 5DGMF 3WEHA 2ONHA 3WJKA 4F6VA 3ZMBA 2F8ZF 5B0MA 3WCJA 5CG5A 1YV5A 5E8HA 3N49F 3RYEA 4OGUA 5IL8A 4DEMF 2F89F 1N23A 3N3LF 3VJAA 5CG6A 2E8WA 5IN8A 5JV1F 4XQSF 1JFGA 1YHLA 3WEJA 1JFAA 3WCDA 5IKAA 2PS5A 1WL0A 3SDRA 1HXAA 2J1OA 2ONGA 3NPRA 4E1EA 5DW7A 3SDQA 3SDUA 5JA0F 3OACA 4K10A 5IM1A 4MC8A 5ILDA 1YQ7A 4NFKF 4F6XA 3WSAA 3M0GA 5JUZF 5ILIA 5IK9A 5EROA 3IBAA 3LDWA 5DHKA 3LG5A 2AEKA 1V4KA 3M02A 3PDEA 2Z7IA 4LA5A 4DHDA 4LLTA 4Q23A 5AELA 4H5CF 3WEIA 4OMHA 1YYUA 1KIYA 4RYPA 3ICKA 5A0KA 3M00A 4XQTF 3RMGA 5A0IA 5IKHA 5DIQF 2ZEVA 5IK6A 1N22A 1YYSA 3DYGA 3CP6A 1WL2A 3IPIA 2Z78A 5DGSF 3WSBA 4FJQA 2ZCRA 5DZ2A 3PH7A 5H9DA 4MC0A 4KWDA 3EFQA 4KPDA 4KK2A 5HNAA 3NPKA 3WCMA 3WCIA 1N1BA 2E8TA 4KVWA 2E8VA 4LA6A 1VG6A 4LLSA 3WCHA 2E8XA 1VG7A 3KRFB 3RYWA 5A0JA 4OKMA 3TFPA 4LIXA 3S4JA 5ILKA 3ZOUA 4N9UA 4E9UA 4JYXA 4MC3A 2F94F 3S9VA 4H5EF 3TFVA 3KRAA 5ERNA 3WCBA 3LJIA 3WCEA 3WCCA 3AQBB 4LXWA 4RXAA 5ILHA 5DJVF 4EA0A 2OA6A 1UBWA 1YYQA 3LGZB 3M01A 4JVJF 2Z4XA 4KUXA 5KSXF 5DGNF 2AELA 2PS4A 3P8LA 3KROB 1WL3A 2E91A 2E4OA 1WKZA 3LMDA 1RQIA 2Q9YA 3P8RA 1VG3A 3OABB 3SAEA 5HN7A 1YYTA 3P5RA 1KIZA 4KKMA 5E8LA 2AZLA 4HD1A 4UMJA 5DHIA 3P5PA 5C05A 3SDVA 2E95A 2E94A 3EGTA 3KRCB 2Z4WA 4P0WA 5HN8A 1YHMA 2J5CA 4LFEA 3N3DA 1V4IA 4XQRF 5JV0F 3ACWA 3VJCA 5ILJA 1VG4A 5B0IA 5IMPA 3VJ9A 2F9KF 3RBMA 5DJRF 1HXGA 5B0JA 1V4EA 1VG2A 1ZW5A 3ZMCA 2J1PA 1V4JA 4LZ0A 3WCAA 4EA2A 1WL1A 4LZ3A 4LPGF 4P0XA 4QPFA 3VJDA 4P0VA 5JV2F 1UBXA 3PYBA 3N46F 4EA1A 1WY0A 5IMNA 3NF2A 4LFGA 3WE9A 4H5DF 1YJ4A 2O1OA 3ICNA 2F92F 3VJ8A 4FP4A 3M9UA 3ASXA 4GP1A 4LTZA 3LGKA 4RXEA 5IK0A 1YYRA 2DH4A 3LVSA 4NFIF 2FORA 3TS7A 3DYHA 2F8CF 1YHKA 2ZCQA 3EZ3A 3ADZA 5ER8A 2AZKA 1UBYA 2FTZA 5AYPA 2Z50A 4DXJA 3CKEA 5EATA 2RAHA 3N45F 2ZCSA 4KFAA 4NFJF 3ICZA 3LLWA 3WC9A 2H8OA 3ZL6A 2E90A 4L2XF 4NKEA 3WEFA 2Z52A 3WJNA 5B01A 3Q2QA 4RXDA 4NG6A 3AQCB 2E92A 5DJPF 3ZCDA 3B7LA 4LZCA 1N1ZA 2OPMA 1HX9A 3LK5A 3V1XA 3V66A 3LSNA 5IMIA 4LTVA 2PS7A 3KBKA 2I19A 1FPSA 1N21A 1V4HA 3G4FA 3AQ0A 3N5JF 3OACB 3Q1OA 1EZFA 4LFVF 4DZWA 3P41A 4NUAA 2PS8A 2Q58A 1PS1A 3LOMA 3WCFA 4KVYA 4LPHF 4RNQA 4KQ5A 4KQUA 5E8KA 4LOBA 3KRFA 4OMGA 3BNXA 3MZVA 5EASA 3DYFA 4WK5A 4LUUA 4DWGA 4KQSA 3AE0A 1N24A 1HM4A 3APZA 3PKOA 2OGDA 2Z7HA 3N0FA 2Z4YA 4ZQ8A 3KB9A 2PS6A 2Q80A 3WEGA 4GAXA 4JXNA 1HXCA 4N1ZF 5B02A 3KROA 5B0LA 2ZCOA 3KRPB 3PYAA 3WJOA 2E93A 2F7MF 3G4DA 3ID0A 3TFNA 2ZY1A 2OPNA 3OABA 3LZ9A 3CC9A 1WMWA 3SDTA 3VJBA 1UBVA 2P1CA 3Q30A 5I1UA 5B00A 3KRCA
chains in the Genus database with same CATH superfamily
3WCGA 5AFXA 2E8UA 3V1VA 3N6KF 4KVIA 3KRAB 3WEKA 1HM7A 1RQJA 3N1VF 3ICMA 2EWGA 4F62A 4JZBA 3N0GA 3TC1A 2VF6A 5ILZA 3N5HF 4DI5A 5B0KA 5IL3A 4PVXF 2Z4ZA 4KPJA 3UCAA 3VJEA 4GA3A 3KRPA 4RXCA 5HN9A 3QQVA 3OYRA 4E9ZA 3NRIA 3WCLA 1DI1A 5ILYA 2Z4VA 2ZEUA 3MAVA 4GP2A 5IVGA 3BNYA 5B03A 4JZXA 4KVDA 1RTRA 2AETA 4QXSF 4DWBA 3Q2ZA 5AHUB 1N20A 3ACYA 3N1WF 2QISA 3LEEA 2AZJA 5ERMA 1DGPA 4PVYF 4JXYA 3W7FA 3ACXA 3QKCA 4NKFA 4OKZA 5EAUA 2Q9ZA 5DGMF 3WEHA 2ONHA 3WJKA 4F6VA 3ZMBA 2F8ZF 5B0MA 3WCJA 5CG5A 1YV5A 5E8HA 3N49F 3RYEA 4OGUA 5IL8A 4DEMF 2F89F 1N23A 3N3LF 3VJAA 5CG6A 2E8WA 5IN8A 5JV1F 4XQSF 1JFGA 1YHLA 3WEJA 1JFAA 3WCDA 5IKAA 2PS5A 1WL0A 3SDRA 1HXAA 2J1OA 2ONGA 3NPRA 4E1EA 5DW7A 3SDQA 3SDUA 5JA0F 3OACA 4K10A 5IM1A 4MC8A 5ILDA 1YQ7A 4NFKF 4F6XA 3WSAA 3M0GA 5JUZF 5ILIA 5IK9A 5EROA 3IBAA 3LDWA 5DHKA 3LG5A 2AEKA 1V4KA 3M02A 3PDEA 2Z7IA 4LA5A 4DHDA 4LLTA 4Q23A 5AELA 4H5CF 3WEIA 4OMHA 1YYUA 1KIYA 4RYPA 3ICKA 5A0KA 3M00A 4XQTF 3RMGA 5A0IA 5IKHA 5DIQF 2ZEVA 5IK6A 1N22A 1YYSA 3DYGA 3CP6A 1WL2A 3IPIA 2Z78A 5DGSF 3WSBA 4FJQA 2ZCRA 5DZ2A 3PH7A 5H9DA 4MC0A 4KWDA 3EFQA 4KPDA 4KK2A 5HNAA 3NPKA 3WCMA 3WCIA 1N1BA 2E8TA 4KVWA 2E8VA 4LA6A 1VG6A 4LLSA 3WCHA 2E8XA 1VG7A 3KRFB 3RYWA 5A0JA 4OKMA 3TFPA 4LIXA 3S4JA 5ILKA 3ZOUA 4N9UA 4E9UA 4JYXA 4MC3A 2F94F 3S9VA 4H5EF 3TFVA 3KRAA 5ERNA 3WCBA 3LJIA 3WCEA 3WCCA 3AQBB 4LXWA 4RXAA 5ILHA 5DJVF 4EA0A 2OA6A 1UBWA 1YYQA 3LGZB 3M01A 4JVJF 2Z4XA 4KUXA 5KSXF 5DGNF 2AELA 2PS4A 3P8LA 3KROB 1WL3A 2E91A 2E4OA 1WKZA 3LMDA 1RQIA 2Q9YA 3P8RA 1VG3A 3OABB 3SAEA 5HN7A 1YYTA 3P5RA 1KIZA 4KKMA 5E8LA 2AZLA 4HD1A 4UMJA 5DHIA 3P5PA 5C05A 3SDVA 2E95A 2E94A 3EGTA 3KRCB 2Z4WA 4P0WA 5HN8A 1YHMA 2J5CA 4LFEA 3N3DA 1V4IA 4XQRF 5JV0F 3ACWA 3VJCA 5ILJA 1VG4A 5B0IA 5IMPA 3VJ9A 2F9KF 3RBMA 5DJRF 1HXGA 5B0JA 1V4EA 1VG2A 1ZW5A 3ZMCA 2J1PA 1V4JA 4LZ0A 3WCAA 4EA2A 1WL1A 4LZ3A 4LPGF 4P0XA 4QPFA 3VJDA 4P0VA 5JV2F 1UBXA 3PYBA 3N46F 4EA1A 1WY0A 5IMNA 3NF2A 4LFGA 3WE9A 4H5DF 1YJ4A 2O1OA 3ICNA 2F92F 3VJ8A 4FP4A 3M9UA 3ASXA 4GP1A 4LTZA 3LGKA 4RXEA 5IK0A 1YYRA 2DH4A 3LVSA 4NFIF 2FORA 3TS7A 3DYHA 2F8CF 1YHKA 2ZCQA 3EZ3A 3ADZA 5ER8A 2AZKA 1UBYA 2FTZA 5AYPA 2Z50A 4DXJA 3CKEA 5EATA 2RAHA 3N45F 2ZCSA 4KFAA 4NFJF 3ICZA 3LLWA 3WC9A 2H8OA 3ZL6A 2E90A 4L2XF 4NKEA 3WEFA 2Z52A 3WJNA 5B01A 3Q2QA 4RXDA 4NG6A 3AQCB 2E92A 5DJPF 3ZCDA 3B7LA 4LZCA 1N1ZA 2OPMA 1HX9A 3LK5A 3V1XA 3V66A 3LSNA 5IMIA 4LTVA 2PS7A 3KBKA 2I19A 1FPSA 1N21A 1V4HA 3G4FA 3AQ0A 3N5JF 3OACB 3Q1OA 1EZFA 4LFVF 4DZWA 3P41A 4NUAA 2PS8A 2Q58A 1PS1A 3LOMA 3WCFA 4KVYA 4LPHF 4RNQA 4KQ5A 4KQUA 5E8KA 4LOBA 3KRFA 4OMGA 3BNXA 3MZVA 5EASA 3DYFA 4WK5A 4LUUA 4DWGA 4KQSA 3AE0A 1N24A 1HM4A 3APZA 3PKOA 2OGDA 2Z7HA 3N0FA 2Z4YA 4ZQ8A 3KB9A 2PS6A 2Q80A 3WEGA 4GAXA 4JXNA 1HXCA 4N1ZF 5B02A 3KROA 5B0LA 2ZCOA 3KRPB 3PYAA 3WJOA 2E93A 2F7MF 3G4DA 3ID0A 3TFNA 2ZY1A 2OPNA 3OABA 3LZ9A 3CC9A 1WMWA 3SDTA 3VJBA 1UBVA 2P1CA 3Q30A 5I1UA 5B00A 3KRCA
chains in the Genus database with same CATH topology
3WCGA 5AFXA 2E8UA 3V1VA 3N6KF 4KVIA 3KRAB 3WEKA 1HM7A 1RQJA 3N1VF 3ICMA 2EWGA 4F62A 4JZBA 3N0GA 3TC1A 2VF6A 5ILZA 3N5HF 4DI5A 5B0KA 5IL3A 4PVXF 2Z4ZA 4KPJA 3UCAA 3VJEA 4GA3A 3KRPA 4RXCA 5HN9A 3QQVA 3OYRA 4E9ZA 3NRIA 3WCLA 1DI1A 5ILYA 2Z4VA 2ZEUA 3MAVA 4GP2A 5IVGA 3BNYA 5B03A 4JZXA 4KVDA 1RTRA 2AETA 4QXSF 4DWBA 3Q2ZA 5AHUB 1N20A 3ACYA 3N1WF 2QISA 3LEEA 2AZJA 5ERMA 1DGPA 4PVYF 4JXYA 3W7FA 3ACXA 3QKCA 4NKFA 4OKZA 5EAUA 2Q9ZA 5DGMF 3WEHA 2ONHA 3WJKA 4F6VA 3ZMBA 2F8ZF 5B0MA 3WCJA 5CG5A 1YV5A 5E8HA 3N49F 3RYEA 4OGUA 5IL8A 4DEMF 2F89F 1N23A 3N3LF 3VJAA 5CG6A 2E8WA 5IN8A 5JV1F 4XQSF 1JFGA 1YHLA 3WEJA 1JFAA 3WCDA 5IKAA 2PS5A 1WL0A 3SDRA 1HXAA 2J1OA 2ONGA 3NPRA 4E1EA 5DW7A 3SDQA 3SDUA 5JA0F 3OACA 4K10A 5IM1A 4MC8A 5ILDA 1YQ7A 4NFKF 4F6XA 3WSAA 3M0GA 5JUZF 5ILIA 5IK9A 5EROA 3IBAA 3LDWA 5DHKA 3LG5A 2AEKA 1V4KA 3M02A 3PDEA 2Z7IA 4LA5A 4DHDA 4LLTA 4Q23A 5AELA 4H5CF 3WEIA 4OMHA 1YYUA 1KIYA 4RYPA 3ICKA 5A0KA 3M00A 4XQTF 3RMGA 5A0IA 5IKHA 5DIQF 2ZEVA 5IK6A 1N22A 1YYSA 3DYGA 3CP6A 1WL2A 3IPIA 2Z78A 5DGSF 3WSBA 4FJQA 2ZCRA 5DZ2A 3PH7A 5H9DA 4MC0A 4KWDA 3EFQA 4KPDA 4KK2A 5HNAA 3NPKA 3WCMA 3WCIA 1N1BA 2E8TA 4KVWA 2E8VA 4LA6A 1VG6A 4LLSA 3WCHA 2E8XA 1VG7A 3KRFB 3RYWA 5A0JA 4OKMA 3TFPA 4LIXA 3S4JA 5ILKA 3ZOUA 4N9UA 4E9UA 4JYXA 4MC3A 2F94F 3S9VA 4H5EF 3TFVA 3KRAA 5ERNA 3WCBA 3LJIA 3WCEA 3WCCA 3AQBB 4LXWA 4RXAA 5ILHA 5DJVF 4EA0A 2OA6A 1UBWA 1YYQA 3LGZB 3M01A 4JVJF 2Z4XA 4KUXA 5KSXF 5DGNF 2AELA 2PS4A 3P8LA 3KROB 1WL3A 2E91A 2E4OA 1WKZA 3LMDA 1RQIA 2Q9YA 3P8RA 1VG3A 3OABB 3SAEA 5HN7A 1YYTA 3P5RA 1KIZA 4KKMA 5E8LA 2AZLA 4HD1A 4UMJA 5DHIA 3P5PA 5C05A 3SDVA 2E95A 2E94A 3EGTA 3KRCB 2Z4WA 4P0WA 5HN8A 1YHMA 2J5CA 4LFEA 3N3DA 1V4IA 4XQRF 5JV0F 3ACWA 3VJCA 5ILJA 1VG4A 5B0IA 5IMPA 3VJ9A 2F9KF 3RBMA 5DJRF 1HXGA 5B0JA 1V4EA 1VG2A 1ZW5A 3ZMCA 2J1PA 1V4JA 4LZ0A 3WCAA 4EA2A 1WL1A 4LZ3A 4LPGF 4P0XA 4QPFA 3VJDA 4P0VA 5JV2F 1UBXA 3PYBA 3N46F 4EA1A 1WY0A 5IMNA 3NF2A 4LFGA 3WE9A 4H5DF 1YJ4A 2O1OA 3ICNA 2F92F 3VJ8A 4FP4A 3M9UA 3ASXA 4GP1A 4LTZA 3LGKA 4RXEA 5IK0A 1YYRA 2DH4A 3LVSA 4NFIF 2FORA 3TS7A 3DYHA 2F8CF 1YHKA 2ZCQA 3EZ3A 3ADZA 5ER8A 2AZKA 1UBYA 2FTZA 5AYPA 2Z50A 4DXJA 3CKEA 5EATA 2RAHA 3N45F 2ZCSA 4KFAA 4NFJF 3ICZA 3LLWA 3WC9A 2H8OA 3ZL6A 2E90A 4L2XF 4NKEA 3WEFA 2Z52A 3WJNA 5B01A 3Q2QA 4RXDA 4NG6A 3AQCB 2E92A 5DJPF 3ZCDA 3B7LA 4LZCA 1N1ZA 2OPMA 1HX9A 3LK5A 3V1XA 3V66A 3LSNA 5IMIA 4LTVA 2PS7A 3KBKA 2I19A 1FPSA 1N21A 1V4HA 3G4FA 3AQ0A 3N5JF 3OACB 3Q1OA 1EZFA 4LFVF 4DZWA 3P41A 4NUAA 2PS8A 2Q58A 1PS1A 3LOMA 3WCFA 4KVYA 4LPHF 4RNQA 4KQ5A 4KQUA 5E8KA 4LOBA 3KRFA 4OMGA 3BNXA 3MZVA 5EASA 3DYFA 4WK5A 4LUUA 4DWGA 4KQSA 3AE0A 1N24A 1HM4A 3APZA 3PKOA 2OGDA 2Z7HA 3N0FA 2Z4YA 4ZQ8A 3KB9A 2PS6A 2Q80A 3WEGA 4GAXA 4JXNA 1HXCA 4N1ZF 5B02A 3KROA 5B0LA 2ZCOA 3KRPB 3PYAA 3WJOA 2E93A 2F7MF 3G4DA 3ID0A 3TFNA 2ZY1A 2OPNA 3OABA 3LZ9A 3CC9A 1WMWA 3SDTA 3VJBA 1UBVA 2P1CA 3Q30A 5I1UA 5B00A 3KRCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3WCG A;  5AFX A;  2E8U A;  3V1V A;  3N6K F;  4KVI A;  3KRA B;  3WEK A;  1HM7 A;  1RQJ A;  3N1V F;  3ICM A;  2EWG A;  4F62 A;  4JZB A;  3N0G A;  3TC1 A;  2VF6 A;  5ILZ A;  3N5H F;  4DI5 A;  5B0K A;  5IL3 A;  4PVX F;  2Z4Z A;  4KPJ A;  3UCA A;  3VJE A;  4GA3 A;  3KRP A;  4RXC A;  5HN9 A;  3QQV A;  3OYR A;  4E9Z A;  3NRI A;  3WCL A;  1DI1 A;  5ILY A;  2Z4V A;  2ZEU A;  3MAV A;  4GP2 A;  5IVG A;  3BNY A;  5B03 A;  4JZX A;  4KVD A;  1RTR A;  2AET A;  4QXS F;  4DWB A;  3Q2Z A;  5AHU B;  1N20 A;  3ACY A;  3N1W F;  2QIS A;  3LEE A;  2AZJ A;  5ERM A;  1DGP A;  4PVY F;  4JXY A;  3W7F A;  3ACX A;  3QKC A;  4NKF A;  4OKZ A;  5EAU A;  2Q9Z A;  5DGM F;  3WEH A;  2ONH A;  3WJK A;  4F6V A;  3ZMB A;  2F8Z F;  5B0M A;  3WCJ A;  5CG5 A;  1YV5 A;  5E8H A;  3N49 F;  3RYE A;  4OGU A;  5IL8 A;  4DEM F;  2F89 F;  1N23 A;  3N3L F;  3VJA A;  5CG6 A;  2E8W A;  5IN8 A;  5JV1 F;  4XQS F;  1JFG A;  1YHL A;  3WEJ A;  1JFA A;  3WCD A;  5IKA A;  2PS5 A;  1WL0 A;  3SDR A;  1HXA A;  2J1O A;  2ONG A;  3NPR A;  4E1E A;  5DW7 A;  3SDQ A;  3SDU A;  5JA0 F;  3OAC A;  4K10 A;  5IM1 A;  4MC8 A;  5ILD A;  1YQ7 A;  4NFK F;  4F6X A;  3WSA A;  3M0G A;  5JUZ F;  5ILI A;  5IK9 A;  5ERO A;  3IBA A;  3LDW A;  5DHK A;  3LG5 A;  2AEK A;  1V4K A;  3M02 A;  3PDE A;  2Z7I A;  4LA5 A;  4DHD A;  4LLT A;  4Q23 A;  5AEL A;  4H5C F;  3WEI A;  4OMH A;  1YYU A;  1KIY A;  4RYP A;  3ICK A;  5A0K A;  3M00 A;  4XQT F;  3RMG A;  5A0I A;  5IKH A;  5DIQ F;  2ZEV A;  5IK6 A;  1N22 A;  1YYS A;  3DYG A;  3CP6 A;  1WL2 A;  3IPI A;  2Z78 A;  5DGS F;  3WSB A;  4FJQ A;  2ZCR A;  5DZ2 A;  3PH7 A;  5H9D A;  4MC0 A;  4KWD A;  3EFQ A;  4KPD A;  4KK2 A;  5HNA A;  3NPK A;  3WCM A;  3WCI A;  1N1B A;  2E8T A;  4KVW A;  2E8V A;  4LA6 A;  1VG6 A;  4LLS A;  3WCH A;  2E8X A;  1VG7 A;  3KRF B;  3RYW A;  5A0J A;  4OKM A;  3TFP A;  4LIX A;  3S4J A;  5ILK A;  3ZOU A;  4N9U A;  4E9U A;  4JYX A;  4MC3 A;  2F94 F;  3S9V A;  4H5E F;  3TFV A;  3KRA A;  5ERN A;  3WCB A;  3LJI A;  3WCE A;  3WCC A;  3AQB B;  4LXW A;  4RXA A;  5ILH A;  5DJV F;  4EA0 A;  2OA6 A;  1UBW A;  1YYQ A;  3LGZ B;  3M01 A;  4JVJ F;  2Z4X A;  4KUX A;  5KSX F;  5DGN F;  2AEL A;  2PS4 A;  3P8L A;  3KRO B;  1WL3 A;  2E91 A;  2E4O A;  1WKZ A;  3LMD A;  1RQI A;  2Q9Y A;  3P8R A;  1VG3 A;  3OAB B;  3SAE A;  5HN7 A;  1YYT A;  3P5R A;  1KIZ A;  4KKM A;  5E8L A;  2AZL A;  4HD1 A;  4UMJ A;  5DHI A;  3P5P A;  5C05 A;  3SDV A;  2E95 A;  2E94 A;  3EGT A;  3KRC B;  2Z4W A;  4P0W A;  5HN8 A;  1YHM A;  2J5C A;  4LFE A;  3N3D A;  1V4I A;  4XQR F;  5JV0 F;  3ACW A;  3VJC A;  5ILJ A;  1VG4 A;  5B0I A;  5IMP A;  3VJ9 A;  2F9K F;  3RBM A;  5DJR F;  1HXG A;  5B0J A;  1V4E A;  1VG2 A;  1ZW5 A;  3ZMC A;  2J1P A;  1V4J A;  4LZ0 A;  3WCA A;  4EA2 A;  1WL1 A;  4LZ3 A;  4LPG F;  4P0X A;  4QPF A;  3VJD A;  4P0V A;  5JV2 F;  1UBX A;  3PYB A;  3N46 F;  4EA1 A;  1WY0 A;  5IMN A;  3NF2 A;  4LFG A;  3WE9 A;  4H5D F;  1YJ4 A;  2O1O A;  3ICN A;  2F92 F;  3VJ8 A;  4FP4 A;  3M9U A;  3ASX A;  4GP1 A;  4LTZ A;  3LGK A;  4RXE A;  5IK0 A;  1YYR A;  2DH4 A;  3LVS A;  4NFI F;  2FOR A;  3TS7 A;  3DYH A;  2F8C F;  1YHK A;  2ZCQ A;  3EZ3 A;  3ADZ A;  5ER8 A;  2AZK A;  1UBY A;  2FTZ A;  5AYP A;  2Z50 A;  4DXJ A;  3CKE A;  5EAT A;  2RAH A;  3N45 F;  2ZCS A;  4KFA A;  4NFJ F;  3ICZ A;  3LLW A;  3WC9 A;  2H8O A;  3ZL6 A;  2E90 A;  4L2X F;  4NKE A;  3WEF A;  2Z52 A;  3WJN A;  5B01 A;  3Q2Q A;  4RXD A;  4NG6 A;  3AQC B;  2E92 A;  5DJP F;  3ZCD A;  3B7L A;  4LZC A;  1N1Z A;  2OPM A;  1HX9 A;  3LK5 A;  3V1X A;  3V66 A;  3LSN A;  5IMI A;  4LTV A;  2PS7 A;  3KBK A;  2I19 A;  1FPS A;  1N21 A;  1V4H A;  3G4F A;  3AQ0 A;  3N5J F;  3OAC B;  3Q1O A;  1EZF A;  4LFV F;  4DZW A;  3P41 A;  4NUA A;  2PS8 A;  2Q58 A;  1PS1 A;  3LOM A;  3WCF A;  4KVY A;  4LPH F;  4RNQ A;  4KQ5 A;  4KQU A;  5E8K A;  4LOB A;  3KRF A;  4OMG A;  3BNX A;  3MZV A;  5EAS A;  3DYF A;  4WK5 A;  4LUU A;  4DWG A;  4KQS A;  3AE0 A;  1N24 A;  1HM4 A;  3APZ A;  3PKO A;  2OGD A;  2Z7H A;  3N0F A;  2Z4Y A;  4ZQ8 A;  3KB9 A;  2PS6 A;  2Q80 A;  3WEG A;  4GAX A;  4JXN A;  1HXC A;  4N1Z F;  5B02 A;  3KRO A;  5B0L A;  2ZCO A;  3KRP B;  3PYA A;  3WJO A;  2E93 A;  2F7M F;  3G4D A;  3ID0 A;  3TFN A;  2ZY1 A;  2OPN A;  3OAB A;  3LZ9 A;  3CC9 A;  1WMW A;  3SDT A;  3VJB A;  1UBV A;  2P1C A;  3Q30 A;  5I1U A;  5B00 A;  3KRC A; 
#chains in the Genus database with same CATH topology
 3WCG A;  5AFX A;  2E8U A;  3V1V A;  3N6K F;  4KVI A;  3KRA B;  3WEK A;  1HM7 A;  1RQJ A;  3N1V F;  3ICM A;  2EWG A;  4F62 A;  4JZB A;  3N0G A;  3TC1 A;  2VF6 A;  5ILZ A;  3N5H F;  4DI5 A;  5B0K A;  5IL3 A;  4PVX F;  2Z4Z A;  4KPJ A;  3UCA A;  3VJE A;  4GA3 A;  3KRP A;  4RXC A;  5HN9 A;  3QQV A;  3OYR A;  4E9Z A;  3NRI A;  3WCL A;  1DI1 A;  5ILY A;  2Z4V A;  2ZEU A;  3MAV A;  4GP2 A;  5IVG A;  3BNY A;  5B03 A;  4JZX A;  4KVD A;  1RTR A;  2AET A;  4QXS F;  4DWB A;  3Q2Z A;  5AHU B;  1N20 A;  3ACY A;  3N1W F;  2QIS A;  3LEE A;  2AZJ A;  5ERM A;  1DGP A;  4PVY F;  4JXY A;  3W7F A;  3ACX A;  3QKC A;  4NKF A;  4OKZ A;  5EAU A;  2Q9Z A;  5DGM F;  3WEH A;  2ONH A;  3WJK A;  4F6V A;  3ZMB A;  2F8Z F;  5B0M A;  3WCJ A;  5CG5 A;  1YV5 A;  5E8H A;  3N49 F;  3RYE A;  4OGU A;  5IL8 A;  4DEM F;  2F89 F;  1N23 A;  3N3L F;  3VJA A;  5CG6 A;  2E8W A;  5IN8 A;  5JV1 F;  4XQS F;  1JFG A;  1YHL A;  3WEJ A;  1JFA A;  3WCD A;  5IKA A;  2PS5 A;  1WL0 A;  3SDR A;  1HXA A;  2J1O A;  2ONG A;  3NPR A;  4E1E A;  5DW7 A;  3SDQ A;  3SDU A;  5JA0 F;  3OAC A;  4K10 A;  5IM1 A;  4MC8 A;  5ILD A;  1YQ7 A;  4NFK F;  4F6X A;  3WSA A;  3M0G A;  5JUZ F;  5ILI A;  5IK9 A;  5ERO A;  3IBA A;  3LDW A;  5DHK A;  3LG5 A;  2AEK A;  1V4K A;  3M02 A;  3PDE A;  2Z7I A;  4LA5 A;  4DHD A;  4LLT A;  4Q23 A;  5AEL A;  4H5C F;  3WEI A;  4OMH A;  1YYU A;  1KIY A;  4RYP A;  3ICK A;  5A0K A;  3M00 A;  4XQT F;  3RMG A;  5A0I A;  5IKH A;  5DIQ F;  2ZEV A;  5IK6 A;  1N22 A;  1YYS A;  3DYG A;  3CP6 A;  1WL2 A;  3IPI A;  2Z78 A;  5DGS F;  3WSB A;  4FJQ A;  2ZCR A;  5DZ2 A;  3PH7 A;  5H9D A;  4MC0 A;  4KWD A;  3EFQ A;  4KPD A;  4KK2 A;  5HNA A;  3NPK A;  3WCM A;  3WCI A;  1N1B A;  2E8T A;  4KVW A;  2E8V A;  4LA6 A;  1VG6 A;  4LLS A;  3WCH A;  2E8X A;  1VG7 A;  3KRF B;  3RYW A;  5A0J A;  4OKM A;  3TFP A;  4LIX A;  3S4J A;  5ILK A;  3ZOU A;  4N9U A;  4E9U A;  4JYX A;  4MC3 A;  2F94 F;  3S9V A;  4H5E F;  3TFV A;  3KRA A;  5ERN A;  3WCB A;  3LJI A;  3WCE A;  3WCC A;  3AQB B;  4LXW A;  4RXA A;  5ILH A;  5DJV F;  4EA0 A;  2OA6 A;  1UBW A;  1YYQ A;  3LGZ B;  3M01 A;  4JVJ F;  2Z4X A;  4KUX A;  5KSX F;  5DGN F;  2AEL A;  2PS4 A;  3P8L A;  3KRO B;  1WL3 A;  2E91 A;  2E4O A;  1WKZ A;  3LMD A;  1RQI A;  2Q9Y A;  3P8R A;  1VG3 A;  3OAB B;  3SAE A;  5HN7 A;  1YYT A;  3P5R A;  1KIZ A;  4KKM A;  5E8L A;  2AZL A;  4HD1 A;  4UMJ A;  5DHI A;  3P5P A;  5C05 A;  3SDV A;  2E95 A;  2E94 A;  3EGT A;  3KRC B;  2Z4W A;  4P0W A;  5HN8 A;  1YHM A;  2J5C A;  4LFE A;  3N3D A;  1V4I A;  4XQR F;  5JV0 F;  3ACW A;  3VJC A;  5ILJ A;  1VG4 A;  5B0I A;  5IMP A;  3VJ9 A;  2F9K F;  3RBM A;  5DJR F;  1HXG A;  5B0J A;  1V4E A;  1VG2 A;  1ZW5 A;  3ZMC A;  2J1P A;  1V4J A;  4LZ0 A;  3WCA A;  4EA2 A;  1WL1 A;  4LZ3 A;  4LPG F;  4P0X A;  4QPF A;  3VJD A;  4P0V A;  5JV2 F;  1UBX A;  3PYB A;  3N46 F;  4EA1 A;  1WY0 A;  5IMN A;  3NF2 A;  4LFG A;  3WE9 A;  4H5D F;  1YJ4 A;  2O1O A;  3ICN A;  2F92 F;  3VJ8 A;  4FP4 A;  3M9U A;  3ASX A;  4GP1 A;  4LTZ A;  3LGK A;  4RXE A;  5IK0 A;  1YYR A;  2DH4 A;  3LVS A;  4NFI F;  2FOR A;  3TS7 A;  3DYH A;  2F8C F;  1YHK A;  2ZCQ A;  3EZ3 A;  3ADZ A;  5ER8 A;  2AZK A;  1UBY A;  2FTZ A;  5AYP A;  2Z50 A;  4DXJ A;  3CKE A;  5EAT A;  2RAH A;  3N45 F;  2ZCS A;  4KFA A;  4NFJ F;  3ICZ A;  3LLW A;  3WC9 A;  2H8O A;  3ZL6 A;  2E90 A;  4L2X F;  4NKE A;  3WEF A;  2Z52 A;  3WJN A;  5B01 A;  3Q2Q A;  4RXD A;  4NG6 A;  3AQC B;  2E92 A;  5DJP F;  3ZCD A;  3B7L A;  4LZC A;  1N1Z A;  2OPM A;  1HX9 A;  3LK5 A;  3V1X A;  3V66 A;  3LSN A;  5IMI A;  4LTV A;  2PS7 A;  3KBK A;  2I19 A;  1FPS A;  1N21 A;  1V4H A;  3G4F A;  3AQ0 A;  3N5J F;  3OAC B;  3Q1O A;  1EZF A;  4LFV F;  4DZW A;  3P41 A;  4NUA A;  2PS8 A;  2Q58 A;  1PS1 A;  3LOM A;  3WCF A;  4KVY A;  4LPH F;  4RNQ A;  4KQ5 A;  4KQU A;  5E8K A;  4LOB A;  3KRF A;  4OMG A;  3BNX A;  3MZV A;  5EAS A;  3DYF A;  4WK5 A;  4LUU A;  4DWG A;  4KQS A;  3AE0 A;  1N24 A;  1HM4 A;  3APZ A;  3PKO A;  2OGD A;  2Z7H A;  3N0F A;  2Z4Y A;  4ZQ8 A;  3KB9 A;  2PS6 A;  2Q80 A;  3WEG A;  4GAX A;  4JXN A;  1HXC A;  4N1Z F;  5B02 A;  3KRO A;  5B0L A;  2ZCO A;  3KRP B;  3PYA A;  3WJO A;  2E93 A;  2F7M F;  3G4D A;  3ID0 A;  3TFN A;  2ZY1 A;  2OPN A;  3OAB A;  3LZ9 A;  3CC9 A;  1WMW A;  3SDT A;  3VJB A;  1UBV A;  2P1C A;  3Q30 A;  5I1U A;  5B00 A;  3KRC A; 
#chains in the Genus database with same CATH homology
 3WCG A;  5AFX A;  2E8U A;  3V1V A;  3N6K F;  4KVI A;  3KRA B;  3WEK A;  1HM7 A;  1RQJ A;  3N1V F;  3ICM A;  2EWG A;  4F62 A;  4JZB A;  3N0G A;  3TC1 A;  2VF6 A;  5ILZ A;  3N5H F;  4DI5 A;  5B0K A;  5IL3 A;  4PVX F;  2Z4Z A;  4KPJ A;  3UCA A;  3VJE A;  4GA3 A;  3KRP A;  4RXC A;  5HN9 A;  3QQV A;  3OYR A;  4E9Z A;  3NRI A;  3WCL A;  1DI1 A;  5ILY A;  2Z4V A;  2ZEU A;  3MAV A;  4GP2 A;  5IVG A;  3BNY A;  5B03 A;  4JZX A;  4KVD A;  1RTR A;  2AET A;  4QXS F;  4DWB A;  3Q2Z A;  5AHU B;  1N20 A;  3ACY A;  3N1W F;  2QIS A;  3LEE A;  2AZJ A;  5ERM A;  1DGP A;  4PVY F;  4JXY A;  3W7F A;  3ACX A;  3QKC A;  4NKF A;  4OKZ A;  5EAU A;  2Q9Z A;  5DGM F;  3WEH A;  2ONH A;  3WJK A;  4F6V A;  3ZMB A;  2F8Z F;  5B0M A;  3WCJ A;  5CG5 A;  1YV5 A;  5E8H A;  3N49 F;  3RYE A;  4OGU A;  5IL8 A;  4DEM F;  2F89 F;  1N23 A;  3N3L F;  3VJA A;  5CG6 A;  2E8W A;  5IN8 A;  5JV1 F;  4XQS F;  1JFG A;  1YHL A;  3WEJ A;  1JFA A;  3WCD A;  5IKA A;  2PS5 A;  1WL0 A;  3SDR A;  1HXA A;  2J1O A;  2ONG A;  3NPR A;  4E1E A;  5DW7 A;  3SDQ A;  3SDU A;  5JA0 F;  3OAC A;  4K10 A;  5IM1 A;  4MC8 A;  5ILD A;  1YQ7 A;  4NFK F;  4F6X A;  3WSA A;  3M0G A;  5JUZ F;  5ILI A;  5IK9 A;  5ERO A;  3IBA A;  3LDW A;  5DHK A;  3LG5 A;  2AEK A;  1V4K A;  3M02 A;  3PDE A;  2Z7I A;  4LA5 A;  4DHD A;  4LLT A;  4Q23 A;  5AEL A;  4H5C F;  3WEI A;  4OMH A;  1YYU A;  1KIY A;  4RYP A;  3ICK A;  5A0K A;  3M00 A;  4XQT F;  3RMG A;  5A0I A;  5IKH A;  5DIQ F;  2ZEV A;  5IK6 A;  1N22 A;  1YYS A;  3DYG A;  3CP6 A;  1WL2 A;  3IPI A;  2Z78 A;  5DGS F;  3WSB A;  4FJQ A;  2ZCR A;  5DZ2 A;  3PH7 A;  5H9D A;  4MC0 A;  4KWD A;  3EFQ A;  4KPD A;  4KK2 A;  5HNA A;  3NPK A;  3WCM A;  3WCI A;  1N1B A;  2E8T A;  4KVW A;  2E8V A;  4LA6 A;  1VG6 A;  4LLS A;  3WCH A;  2E8X A;  1VG7 A;  3KRF B;  3RYW A;  5A0J A;  4OKM A;  3TFP A;  4LIX A;  3S4J A;  5ILK A;  3ZOU A;  4N9U A;  4E9U A;  4JYX A;  4MC3 A;  2F94 F;  3S9V A;  4H5E F;  3TFV A;  3KRA A;  5ERN A;  3WCB A;  3LJI A;  3WCE A;  3WCC A;  3AQB B;  4LXW A;  4RXA A;  5ILH A;  5DJV F;  4EA0 A;  2OA6 A;  1UBW A;  1YYQ A;  3LGZ B;  3M01 A;  4JVJ F;  2Z4X A;  4KUX A;  5KSX F;  5DGN F;  2AEL A;  2PS4 A;  3P8L A;  3KRO B;  1WL3 A;  2E91 A;  2E4O A;  1WKZ A;  3LMD A;  1RQI A;  2Q9Y A;  3P8R A;  1VG3 A;  3OAB B;  3SAE A;  5HN7 A;  1YYT A;  3P5R A;  1KIZ A;  4KKM A;  5E8L A;  2AZL A;  4HD1 A;  4UMJ A;  5DHI A;  3P5P A;  5C05 A;  3SDV A;  2E95 A;  2E94 A;  3EGT A;  3KRC B;  2Z4W A;  4P0W A;  5HN8 A;  1YHM A;  2J5C A;  4LFE A;  3N3D A;  1V4I A;  4XQR F;  5JV0 F;  3ACW A;  3VJC A;  5ILJ A;  1VG4 A;  5B0I A;  5IMP A;  3VJ9 A;  2F9K F;  3RBM A;  5DJR F;  1HXG A;  5B0J A;  1V4E A;  1VG2 A;  1ZW5 A;  3ZMC A;  2J1P A;  1V4J A;  4LZ0 A;  3WCA A;  4EA2 A;  1WL1 A;  4LZ3 A;  4LPG F;  4P0X A;  4QPF A;  3VJD A;  4P0V A;  5JV2 F;  1UBX A;  3PYB A;  3N46 F;  4EA1 A;  1WY0 A;  5IMN A;  3NF2 A;  4LFG A;  3WE9 A;  4H5D F;  1YJ4 A;  2O1O A;  3ICN A;  2F92 F;  3VJ8 A;  4FP4 A;  3M9U A;  3ASX A;  4GP1 A;  4LTZ A;  3LGK A;  4RXE A;  5IK0 A;  1YYR A;  2DH4 A;  3LVS A;  4NFI F;  2FOR A;  3TS7 A;  3DYH A;  2F8C F;  1YHK A;  2ZCQ A;  3EZ3 A;  3ADZ A;  5ER8 A;  2AZK A;  1UBY A;  2FTZ A;  5AYP A;  2Z50 A;  4DXJ A;  3CKE A;  5EAT A;  2RAH A;  3N45 F;  2ZCS A;  4KFA A;  4NFJ F;  3ICZ A;  3LLW A;  3WC9 A;  2H8O A;  3ZL6 A;  2E90 A;  4L2X F;  4NKE A;  3WEF A;  2Z52 A;  3WJN A;  5B01 A;  3Q2Q A;  4RXD A;  4NG6 A;  3AQC B;  2E92 A;  5DJP F;  3ZCD A;  3B7L A;  4LZC A;  1N1Z A;  2OPM A;  1HX9 A;  3LK5 A;  3V1X A;  3V66 A;  3LSN A;  5IMI A;  4LTV A;  2PS7 A;  3KBK A;  2I19 A;  1FPS A;  1N21 A;  1V4H A;  3G4F A;  3AQ0 A;  3N5J F;  3OAC B;  3Q1O A;  1EZF A;  4LFV F;  4DZW A;  3P41 A;  4NUA A;  2PS8 A;  2Q58 A;  1PS1 A;  3LOM A;  3WCF A;  4KVY A;  4LPH F;  4RNQ A;  4KQ5 A;  4KQU A;  5E8K A;  4LOB A;  3KRF A;  4OMG A;  3BNX A;  3MZV A;  5EAS A;  3DYF A;  4WK5 A;  4LUU A;  4DWG A;  4KQS A;  3AE0 A;  1N24 A;  1HM4 A;  3APZ A;  3PKO A;  2OGD A;  2Z7H A;  3N0F A;  2Z4Y A;  4ZQ8 A;  3KB9 A;  2PS6 A;  2Q80 A;  3WEG A;  4GAX A;  4JXN A;  1HXC A;  4N1Z F;  5B02 A;  3KRO A;  5B0L A;  2ZCO A;  3KRP B;  3PYA A;  3WJO A;  2E93 A;  2F7M F;  3G4D A;  3ID0 A;  3TFN A;  2ZY1 A;  2OPN A;  3OAB A;  3LZ9 A;  3CC9 A;  1WMW A;  3SDT A;  3VJB A;  1UBV A;  2P1C A;  3Q30 A;  5I1U A;  5B00 A;  3KRC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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