4DEMF

Crystal structure of human fpps in complex with ys_04_70
Total Genus 138
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
138
sequence length
346
structure length
346
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule keywords Farnesyl pyrophosphate synthase
publication title Design and Synthesis of Active Site Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Apoptosis and Inhibition of ERK Phosphorylation in Multiple Myeloma Cells.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase/transferase inhibitor
total genus 138
structure length 346
sequence length 346
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2012-01-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4demF00
4LIXA 3M02A 5IKHA 4OGUA 1V4KA 3DYFA 1YV5A 2E8UA 3N3DA 3CKEA 2AELA 3OYRA 3Q1OA 5DHKA 4LZ3A 1FPSA 2Q58A 4FP4A 2I19A 3N0GA 3KRAB 4QXSF 4PVYF 5ILKA 4N9UA 2ZCSA 2AZKA 3BNYA 4EA2A 4KQ5A 5B03A 2F89F 5E8LA 1JFGA 4NKEA 5DZ2A 3WJOA 2PS7A 1KIYA 4XQTF 3P8RA 4L2XF 3WEIA 4LPHF 1HM7A 2ONGA 1YYQA 5E8KA 2DH4A 5IL3A 1HXCA 3TFVA 3WCLA 3S4JA 5DIQF 4E1EA 3ID0A 3WEGA 4UMJA 1YHKA 4GA3A 5B0LA 1DGPA 4NFKF 1YJ4A 5IM1A 3KRFA 4H5CF 3RYEA 3Q30A 2Z4YA 3N5JF 3V66A 3VJEA 4NG6A 5ILZA 4N1ZF 2ZCOA 3WCFA 4QPFA 5JA0F 3ADZA 5ER8A 4LA6A 4JVJF 2Z78A 3M0GA 2E8XA 3LJIA 3PKOA 5AHUB 4LA5A 4RXCA 1HM4A 4KVIA 3N6KF 5DJVF 3KROA 3ICKA 2VF6A 2Z7IA 5DGMF 4LXWA 3VJAA 4FJQA 2FTZA 4RNQA 2P1CA 1HX9A 3LZ9A 3KRPA 5AYPA 3ACXA 5ILDA 4LZCA 4RXAA 3ZMCA 2E4OA 4KVWA 4JYXA 1WL1A 5A0JA 3EZ3A 1RQJA 4NFJF 5ILIA 5DJRF 2J1OA 3WC9A 4E9ZA 3VJCA 3V1XA 2FORA 2J1PA 3OABA 3QQVA 4MC3A 3WJNA 2OPMA 5B0KA 3M9UA 4P0XA 4PVXF 3DYHA 4RXDA 2ZEUA 3P41A 2F8CF 4JZBA 4P0WA 2H8OA 4GP2A 4P0VA 4F6VA 5DW7A 4KK2A 3G4DA 4LTZA 2E8WA 3SAEA 3WCCA 3CP6A 1N23A 4EA1A 3OACA 1YHMA 2ONHA 1ZW5A 4JXNA 2Z50A 2F92F 3ZCDA 5IVGA 4NFIF 3RMGA 5ERMA 1WL3A 3KRFB 5DGNF 2Q9YA 3V1VA 5HN9A 1RTRA 4LUUA 5B00A 4DEMF 1YYTA 4LLSA 4OKMA 4KPJA 4KQSA 3B7LA 4LZ0A 1HXGA 2F94F 2E91A 4DI5A 1UBXA 4XQRF 1YYSA 5B0JA 3WCIA 3LSNA 1VG2A 5I1UA 3LG5A 5AFXA 3ICNA 1YYRA 1N1BA 3KBKA 4LFEA 2PS8A 1PS1A 3ZL6A 5B01A 3N46F 4HD1A 5JV0F 3KRPB 1V4IA 4NKFA 3AQCB 3KB9A 3WCHA 2AZLA 3MAVA 3LGZB 5A0KA 1VG3A 3N0FA 4DXJA 3RBMA 3PYBA 4RYPA 3WCDA 2F8ZF 1VG6A 5CG6A 4MC8A 1JFAA 5IMNA 2F7MF 3NRIA 3TFNA 4KFAA 5EASA 3LMDA 3CC9A 3WEFA 5JUZF 3IBAA 1YYUA 3OABB 5HNAA 2ZEVA 5HN8A 2F9KF 2E95A 3QKCA 2OA6A 4OKZA 1WY0A 2Q9ZA 4RXEA 3LVSA 1V4HA 4H5EF 3LK5A 2AEKA 3ZMBA 5IMPA 2O1OA 4DHDA 3ACWA 1UBVA 3N3LF 4WK5A 2OPNA 2Z4VA 3WEKA 4LFVF 3ICZA 3PH7A 3Q2QA 5DJPF 3WCGA 3OACB 3VJ9A 3TS7A 5E8HA 5JV1F 3WCEA 5B0MA 3KRCA 3MZVA 1N1ZA 2AETA 2Z7HA 3WSBA 3VJDA 4KPDA 3N5HF 3LLWA 4ZQ8A 4KUXA 3SDRA 2Z4ZA 5A0IA 2E94A 3LGKA 4F62A 5IK9A 4KQUA 2E92A 3ASXA 1N22A 1YQ7A 3TC1A 3APZA 5IMIA 4MC0A 4KKMA 5CG5A 1EZFA 1DI1A 2EWGA 2AZJA 3WCMA 2Z52A 3LDWA 3EGTA 5B02A 4KWDA 2E90A 1UBYA 4DWBA 3P8LA 3G4FA 5DHIA 3WCAA 3N1WF 3VJBA 5B0IA 5IL8A 3WCJA 5ILJA 3ACYA 4LPGF 1VG4A 2RAHA 5IK6A 3ZOUA 5IKAA 4LLTA 2J5CA 3RYWA 4LTVA 5KSXF 3AQBB 4E9UA 2ZCRA 4H5DF 4GP1A 3AQ0A 3PDEA 3SDQA 3KROB 5EATA 3WE9A 5EROA 4LFGA 4KVDA 1V4JA 4XQSF 3SDVA 4OMGA 3N45F 3P5PA 3WCBA 5IK0A 5AELA 5JV2F 3LOMA 1VG7A 3WEHA 5ILHA 4DWGA 5DGSF 3KRAA 2E8VA 4KVYA 2E8TA 4JZXA 3N1VF 5C05A 3AE0A 3VJ8A 4GAXA 4LOBA 3TFPA 5H9DA 3EFQA 3KRCB 5HN7A 3Q2ZA 3IPIA 4JXYA 3M00A 1RQIA 2ZY1A 3P5RA 4F6XA 2QISA 1WL0A 5ERNA 2PS4A 3WEJA 4OMHA 1N20A 3PYAA 5EAUA 4DZWA 3NPKA 1KIZA 3W7FA 3WJKA 2E93A 4EA0A 3BNXA 4NUAA 5ILYA 3S9VA 2Z4XA 2Z4WA 1WL2A 2Q80A 1WMWA 2PS5A 3WSAA 1N24A 3DYGA 3SDUA 4K10A 3UCAA 4Q23A 3NF2A 3SDTA 1WKZA 2OGDA 3M01A 1YHLA 3LEEA 5IN8A 2PS6A 3ICMA 3N49F 3NPRA 1N21A 1UBWA 1V4EA 1HXAA 2ZCQA
chains in the Genus database with same CATH superfamily
4LIXA 3M02A 5IKHA 4OGUA 1V4KA 3DYFA 1YV5A 2E8UA 3N3DA 3CKEA 2AELA 3OYRA 3Q1OA 5DHKA 4LZ3A 1FPSA 2Q58A 4FP4A 2I19A 3N0GA 3KRAB 4QXSF 4PVYF 5ILKA 4N9UA 2ZCSA 2AZKA 3BNYA 4EA2A 4KQ5A 5B03A 2F89F 5E8LA 1JFGA 4NKEA 5DZ2A 3WJOA 2PS7A 1KIYA 4XQTF 3P8RA 4L2XF 3WEIA 4LPHF 1HM7A 2ONGA 1YYQA 5E8KA 2DH4A 5IL3A 1HXCA 3TFVA 3WCLA 3S4JA 5DIQF 4E1EA 3ID0A 3WEGA 4UMJA 1YHKA 4GA3A 5B0LA 1DGPA 4NFKF 1YJ4A 5IM1A 3KRFA 4H5CF 3RYEA 3Q30A 2Z4YA 3N5JF 3V66A 3VJEA 4NG6A 5ILZA 4N1ZF 2ZCOA 3WCFA 4QPFA 5JA0F 3ADZA 5ER8A 4LA6A 4JVJF 2Z78A 3M0GA 2E8XA 3LJIA 3PKOA 5AHUB 4LA5A 4RXCA 1HM4A 4KVIA 3N6KF 5DJVF 3KROA 3ICKA 2VF6A 2Z7IA 5DGMF 4LXWA 3VJAA 4FJQA 2FTZA 4RNQA 2P1CA 1HX9A 3LZ9A 3KRPA 5AYPA 3ACXA 5ILDA 4LZCA 4RXAA 3ZMCA 2E4OA 4KVWA 4JYXA 1WL1A 5A0JA 3EZ3A 1RQJA 4NFJF 5ILIA 5DJRF 2J1OA 3WC9A 4E9ZA 3VJCA 3V1XA 2FORA 2J1PA 3OABA 3QQVA 4MC3A 3WJNA 2OPMA 5B0KA 3M9UA 4P0XA 4PVXF 3DYHA 4RXDA 2ZEUA 3P41A 2F8CF 4JZBA 4P0WA 2H8OA 4GP2A 4P0VA 4F6VA 5DW7A 4KK2A 3G4DA 4LTZA 2E8WA 3SAEA 3WCCA 3CP6A 1N23A 4EA1A 3OACA 1YHMA 2ONHA 1ZW5A 4JXNA 2Z50A 2F92F 3ZCDA 5IVGA 4NFIF 3RMGA 5ERMA 1WL3A 3KRFB 5DGNF 2Q9YA 3V1VA 5HN9A 1RTRA 4LUUA 5B00A 4DEMF 1YYTA 4LLSA 4OKMA 4KPJA 4KQSA 3B7LA 4LZ0A 1HXGA 2F94F 2E91A 4DI5A 1UBXA 4XQRF 1YYSA 5B0JA 3WCIA 3LSNA 1VG2A 5I1UA 3LG5A 5AFXA 3ICNA 1YYRA 1N1BA 3KBKA 4LFEA 2PS8A 1PS1A 3ZL6A 5B01A 3N46F 4HD1A 5JV0F 3KRPB 1V4IA 4NKFA 3AQCB 3KB9A 3WCHA 2AZLA 3MAVA 3LGZB 5A0KA 1VG3A 3N0FA 4DXJA 3RBMA 3PYBA 4RYPA 3WCDA 2F8ZF 1VG6A 5CG6A 4MC8A 1JFAA 5IMNA 2F7MF 3NRIA 3TFNA 4KFAA 5EASA 3LMDA 3CC9A 3WEFA 5JUZF 3IBAA 1YYUA 3OABB 5HNAA 2ZEVA 5HN8A 2F9KF 2E95A 3QKCA 2OA6A 4OKZA 1WY0A 2Q9ZA 4RXEA 3LVSA 1V4HA 4H5EF 3LK5A 2AEKA 3ZMBA 5IMPA 2O1OA 4DHDA 3ACWA 1UBVA 3N3LF 4WK5A 2OPNA 2Z4VA 3WEKA 4LFVF 3ICZA 3PH7A 3Q2QA 5DJPF 3WCGA 3OACB 3VJ9A 3TS7A 5E8HA 5JV1F 3WCEA 5B0MA 3KRCA 3MZVA 1N1ZA 2AETA 2Z7HA 3WSBA 3VJDA 4KPDA 3N5HF 3LLWA 4ZQ8A 4KUXA 3SDRA 2Z4ZA 5A0IA 2E94A 3LGKA 4F62A 5IK9A 4KQUA 2E92A 3ASXA 1N22A 1YQ7A 3TC1A 3APZA 5IMIA 4MC0A 4KKMA 5CG5A 1EZFA 1DI1A 2EWGA 2AZJA 3WCMA 2Z52A 3LDWA 3EGTA 5B02A 4KWDA 2E90A 1UBYA 4DWBA 3P8LA 3G4FA 5DHIA 3WCAA 3N1WF 3VJBA 5B0IA 5IL8A 3WCJA 5ILJA 3ACYA 4LPGF 1VG4A 2RAHA 5IK6A 3ZOUA 5IKAA 4LLTA 2J5CA 3RYWA 4LTVA 5KSXF 3AQBB 4E9UA 2ZCRA 4H5DF 4GP1A 3AQ0A 3PDEA 3SDQA 3KROB 5EATA 3WE9A 5EROA 4LFGA 4KVDA 1V4JA 4XQSF 3SDVA 4OMGA 3N45F 3P5PA 3WCBA 5IK0A 5AELA 5JV2F 3LOMA 1VG7A 3WEHA 5ILHA 4DWGA 5DGSF 3KRAA 2E8VA 4KVYA 2E8TA 4JZXA 3N1VF 5C05A 3AE0A 3VJ8A 4GAXA 4LOBA 3TFPA 5H9DA 3EFQA 3KRCB 5HN7A 3Q2ZA 3IPIA 4JXYA 3M00A 1RQIA 2ZY1A 3P5RA 4F6XA 2QISA 1WL0A 5ERNA 2PS4A 3WEJA 4OMHA 1N20A 3PYAA 5EAUA 4DZWA 3NPKA 1KIZA 3W7FA 3WJKA 2E93A 4EA0A 3BNXA 4NUAA 5ILYA 3S9VA 2Z4XA 2Z4WA 1WL2A 2Q80A 1WMWA 2PS5A 3WSAA 1N24A 3DYGA 3SDUA 4K10A 3UCAA 4Q23A 3NF2A 3SDTA 1WKZA 2OGDA 3M01A 1YHLA 3LEEA 5IN8A 2PS6A 3ICMA 3N49F 3NPRA 1N21A 1UBWA 1V4EA 1HXAA 2ZCQA
chains in the Genus database with same CATH topology
4LIXA 3M02A 5IKHA 4OGUA 1V4KA 3DYFA 1YV5A 2E8UA 3N3DA 3CKEA 2AELA 3OYRA 3Q1OA 5DHKA 4LZ3A 1FPSA 2Q58A 4FP4A 2I19A 3N0GA 3KRAB 4QXSF 4PVYF 5ILKA 4N9UA 2ZCSA 2AZKA 3BNYA 4EA2A 4KQ5A 5B03A 2F89F 5E8LA 1JFGA 4NKEA 5DZ2A 3WJOA 2PS7A 1KIYA 4XQTF 3P8RA 4L2XF 3WEIA 4LPHF 1HM7A 2ONGA 1YYQA 5E8KA 2DH4A 5IL3A 1HXCA 3TFVA 3WCLA 3S4JA 5DIQF 4E1EA 3ID0A 3WEGA 4UMJA 1YHKA 4GA3A 5B0LA 1DGPA 4NFKF 1YJ4A 5IM1A 3KRFA 4H5CF 3RYEA 3Q30A 2Z4YA 3N5JF 3V66A 3VJEA 4NG6A 5ILZA 4N1ZF 2ZCOA 3WCFA 4QPFA 5JA0F 3ADZA 5ER8A 4LA6A 4JVJF 2Z78A 3M0GA 2E8XA 3LJIA 3PKOA 5AHUB 4LA5A 4RXCA 1HM4A 4KVIA 3N6KF 5DJVF 3KROA 3ICKA 2VF6A 2Z7IA 5DGMF 4LXWA 3VJAA 4FJQA 2FTZA 4RNQA 2P1CA 1HX9A 3LZ9A 3KRPA 5AYPA 3ACXA 5ILDA 4LZCA 4RXAA 3ZMCA 2E4OA 4KVWA 4JYXA 1WL1A 5A0JA 3EZ3A 1RQJA 4NFJF 5ILIA 5DJRF 2J1OA 3WC9A 4E9ZA 3VJCA 3V1XA 2FORA 2J1PA 3OABA 3QQVA 4MC3A 3WJNA 2OPMA 5B0KA 3M9UA 4P0XA 4PVXF 3DYHA 4RXDA 2ZEUA 3P41A 2F8CF 4JZBA 4P0WA 2H8OA 4GP2A 4P0VA 4F6VA 5DW7A 4KK2A 3G4DA 4LTZA 2E8WA 3SAEA 3WCCA 3CP6A 1N23A 4EA1A 3OACA 1YHMA 2ONHA 1ZW5A 4JXNA 2Z50A 2F92F 3ZCDA 5IVGA 4NFIF 3RMGA 5ERMA 1WL3A 3KRFB 5DGNF 2Q9YA 3V1VA 5HN9A 1RTRA 4LUUA 5B00A 4DEMF 1YYTA 4LLSA 4OKMA 4KPJA 4KQSA 3B7LA 4LZ0A 1HXGA 2F94F 2E91A 4DI5A 1UBXA 4XQRF 1YYSA 5B0JA 3WCIA 3LSNA 1VG2A 5I1UA 3LG5A 5AFXA 3ICNA 1YYRA 1N1BA 3KBKA 4LFEA 2PS8A 1PS1A 3ZL6A 5B01A 3N46F 4HD1A 5JV0F 3KRPB 1V4IA 4NKFA 3AQCB 3KB9A 3WCHA 2AZLA 3MAVA 3LGZB 5A0KA 1VG3A 3N0FA 4DXJA 3RBMA 3PYBA 4RYPA 3WCDA 2F8ZF 1VG6A 5CG6A 4MC8A 1JFAA 5IMNA 2F7MF 3NRIA 3TFNA 4KFAA 5EASA 3LMDA 3CC9A 3WEFA 5JUZF 3IBAA 1YYUA 3OABB 5HNAA 2ZEVA 5HN8A 2F9KF 2E95A 3QKCA 2OA6A 4OKZA 1WY0A 2Q9ZA 4RXEA 3LVSA 1V4HA 4H5EF 3LK5A 2AEKA 3ZMBA 5IMPA 2O1OA 4DHDA 3ACWA 1UBVA 3N3LF 4WK5A 2OPNA 2Z4VA 3WEKA 4LFVF 3ICZA 3PH7A 3Q2QA 5DJPF 3WCGA 3OACB 3VJ9A 3TS7A 5E8HA 5JV1F 3WCEA 5B0MA 3KRCA 3MZVA 1N1ZA 2AETA 2Z7HA 3WSBA 3VJDA 4KPDA 3N5HF 3LLWA 4ZQ8A 4KUXA 3SDRA 2Z4ZA 5A0IA 2E94A 3LGKA 4F62A 5IK9A 4KQUA 2E92A 3ASXA 1N22A 1YQ7A 3TC1A 3APZA 5IMIA 4MC0A 4KKMA 5CG5A 1EZFA 1DI1A 2EWGA 2AZJA 3WCMA 2Z52A 3LDWA 3EGTA 5B02A 4KWDA 2E90A 1UBYA 4DWBA 3P8LA 3G4FA 5DHIA 3WCAA 3N1WF 3VJBA 5B0IA 5IL8A 3WCJA 5ILJA 3ACYA 4LPGF 1VG4A 2RAHA 5IK6A 3ZOUA 5IKAA 4LLTA 2J5CA 3RYWA 4LTVA 5KSXF 3AQBB 4E9UA 2ZCRA 4H5DF 4GP1A 3AQ0A 3PDEA 3SDQA 3KROB 5EATA 3WE9A 5EROA 4LFGA 4KVDA 1V4JA 4XQSF 3SDVA 4OMGA 3N45F 3P5PA 3WCBA 5IK0A 5AELA 5JV2F 3LOMA 1VG7A 3WEHA 5ILHA 4DWGA 5DGSF 3KRAA 2E8VA 4KVYA 2E8TA 4JZXA 3N1VF 5C05A 3AE0A 3VJ8A 4GAXA 4LOBA 3TFPA 5H9DA 3EFQA 3KRCB 5HN7A 3Q2ZA 3IPIA 4JXYA 3M00A 1RQIA 2ZY1A 3P5RA 4F6XA 2QISA 1WL0A 5ERNA 2PS4A 3WEJA 4OMHA 1N20A 3PYAA 5EAUA 4DZWA 3NPKA 1KIZA 3W7FA 3WJKA 2E93A 4EA0A 3BNXA 4NUAA 5ILYA 3S9VA 2Z4XA 2Z4WA 1WL2A 2Q80A 1WMWA 2PS5A 3WSAA 1N24A 3DYGA 3SDUA 4K10A 3UCAA 4Q23A 3NF2A 3SDTA 1WKZA 2OGDA 3M01A 1YHLA 3LEEA 5IN8A 2PS6A 3ICMA 3N49F 3NPRA 1N21A 1UBWA 1V4EA 1HXAA 2ZCQA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4LIX A;  3M02 A;  5IKH A;  4OGU A;  1V4K A;  3DYF A;  1YV5 A;  2E8U A;  3N3D A;  3CKE A;  2AEL A;  3OYR A;  3Q1O A;  5DHK A;  4LZ3 A;  1FPS A;  2Q58 A;  4FP4 A;  2I19 A;  3N0G A;  3KRA B;  4QXS F;  4PVY F;  5ILK A;  4N9U A;  2ZCS A;  2AZK A;  3BNY A;  4EA2 A;  4KQ5 A;  5B03 A;  2F89 F;  5E8L A;  1JFG A;  4NKE A;  5DZ2 A;  3WJO A;  2PS7 A;  1KIY A;  4XQT F;  3P8R A;  4L2X F;  3WEI A;  4LPH F;  1HM7 A;  2ONG A;  1YYQ A;  5E8K A;  2DH4 A;  5IL3 A;  1HXC A;  3TFV A;  3WCL A;  3S4J A;  5DIQ F;  4E1E A;  3ID0 A;  3WEG A;  4UMJ A;  1YHK A;  4GA3 A;  5B0L A;  1DGP A;  4NFK F;  1YJ4 A;  5IM1 A;  3KRF A;  4H5C F;  3RYE A;  3Q30 A;  2Z4Y A;  3N5J F;  3V66 A;  3VJE A;  4NG6 A;  5ILZ A;  4N1Z F;  2ZCO A;  3WCF A;  4QPF A;  5JA0 F;  3ADZ A;  5ER8 A;  4LA6 A;  4JVJ F;  2Z78 A;  3M0G A;  2E8X A;  3LJI A;  3PKO A;  5AHU B;  4LA5 A;  4RXC A;  1HM4 A;  4KVI A;  3N6K F;  5DJV F;  3KRO A;  3ICK A;  2VF6 A;  2Z7I A;  5DGM F;  4LXW A;  3VJA A;  4FJQ A;  2FTZ A;  4RNQ A;  2P1C A;  1HX9 A;  3LZ9 A;  3KRP A;  5AYP A;  3ACX A;  5ILD A;  4LZC A;  4RXA A;  3ZMC A;  2E4O A;  4KVW A;  4JYX A;  1WL1 A;  5A0J A;  3EZ3 A;  1RQJ A;  4NFJ F;  5ILI A;  5DJR F;  2J1O A;  3WC9 A;  4E9Z A;  3VJC A;  3V1X A;  2FOR A;  2J1P A;  3OAB A;  3QQV A;  4MC3 A;  3WJN A;  2OPM A;  5B0K A;  3M9U A;  4P0X A;  4PVX F;  3DYH A;  4RXD A;  2ZEU A;  3P41 A;  2F8C F;  4JZB A;  4P0W A;  2H8O A;  4GP2 A;  4P0V A;  4F6V A;  5DW7 A;  4KK2 A;  3G4D A;  4LTZ A;  2E8W A;  3SAE A;  3WCC A;  3CP6 A;  1N23 A;  4EA1 A;  3OAC A;  1YHM A;  2ONH A;  1ZW5 A;  4JXN A;  2Z50 A;  2F92 F;  3ZCD A;  5IVG A;  4NFI F;  3RMG A;  5ERM A;  1WL3 A;  3KRF B;  5DGN F;  2Q9Y A;  3V1V A;  5HN9 A;  1RTR A;  4LUU A;  5B00 A;  4DEM F;  1YYT A;  4LLS A;  4OKM A;  4KPJ A;  4KQS A;  3B7L A;  4LZ0 A;  1HXG A;  2F94 F;  2E91 A;  4DI5 A;  1UBX A;  4XQR F;  1YYS A;  5B0J A;  3WCI A;  3LSN A;  1VG2 A;  5I1U A;  3LG5 A;  5AFX A;  3ICN A;  1YYR A;  1N1B A;  3KBK A;  4LFE A;  2PS8 A;  1PS1 A;  3ZL6 A;  5B01 A;  3N46 F;  4HD1 A;  5JV0 F;  3KRP B;  1V4I A;  4NKF A;  3AQC B;  3KB9 A;  3WCH A;  2AZL A;  3MAV A;  3LGZ B;  5A0K A;  1VG3 A;  3N0F A;  4DXJ A;  3RBM A;  3PYB A;  4RYP A;  3WCD A;  2F8Z F;  1VG6 A;  5CG6 A;  4MC8 A;  1JFA A;  5IMN A;  2F7M F;  3NRI A;  3TFN A;  4KFA A;  5EAS A;  3LMD A;  3CC9 A;  3WEF A;  5JUZ F;  3IBA A;  1YYU A;  3OAB B;  5HNA A;  2ZEV A;  5HN8 A;  2F9K F;  2E95 A;  3QKC A;  2OA6 A;  4OKZ A;  1WY0 A;  2Q9Z A;  4RXE A;  3LVS A;  1V4H A;  4H5E F;  3LK5 A;  2AEK A;  3ZMB A;  5IMP A;  2O1O A;  4DHD A;  3ACW A;  1UBV A;  3N3L F;  4WK5 A;  2OPN A;  2Z4V A;  3WEK A;  4LFV F;  3ICZ A;  3PH7 A;  3Q2Q A;  5DJP F;  3WCG A;  3OAC B;  3VJ9 A;  3TS7 A;  5E8H A;  5JV1 F;  3WCE A;  5B0M A;  3KRC A;  3MZV A;  1N1Z A;  2AET A;  2Z7H A;  3WSB A;  3VJD A;  4KPD A;  3N5H F;  3LLW A;  4ZQ8 A;  4KUX A;  3SDR A;  2Z4Z A;  5A0I A;  2E94 A;  3LGK A;  4F62 A;  5IK9 A;  4KQU A;  2E92 A;  3ASX A;  1N22 A;  1YQ7 A;  3TC1 A;  3APZ A;  5IMI A;  4MC0 A;  4KKM A;  5CG5 A;  1EZF A;  1DI1 A;  2EWG A;  2AZJ A;  3WCM A;  2Z52 A;  3LDW A;  3EGT A;  5B02 A;  4KWD A;  2E90 A;  1UBY A;  4DWB A;  3P8L A;  3G4F A;  5DHI A;  3WCA A;  3N1W F;  3VJB A;  5B0I A;  5IL8 A;  3WCJ A;  5ILJ A;  3ACY A;  4LPG F;  1VG4 A;  2RAH A;  5IK6 A;  3ZOU A;  5IKA A;  4LLT A;  2J5C A;  3RYW A;  4LTV A;  5KSX F;  3AQB B;  4E9U A;  2ZCR A;  4H5D F;  4GP1 A;  3AQ0 A;  3PDE A;  3SDQ A;  3KRO B;  5EAT A;  3WE9 A;  5ERO A;  4LFG A;  4KVD A;  1V4J A;  4XQS F;  3SDV A;  4OMG A;  3N45 F;  3P5P A;  3WCB A;  5IK0 A;  5AEL A;  5JV2 F;  3LOM A;  1VG7 A;  3WEH A;  5ILH A;  4DWG A;  5DGS F;  3KRA A;  2E8V A;  4KVY A;  2E8T A;  4JZX A;  3N1V F;  5C05 A;  3AE0 A;  3VJ8 A;  4GAX A;  4LOB A;  3TFP A;  5H9D A;  3EFQ A;  3KRC B;  5HN7 A;  3Q2Z A;  3IPI A;  4JXY A;  3M00 A;  1RQI A;  2ZY1 A;  3P5R A;  4F6X A;  2QIS A;  1WL0 A;  5ERN A;  2PS4 A;  3WEJ A;  4OMH A;  1N20 A;  3PYA A;  5EAU A;  4DZW A;  3NPK A;  1KIZ A;  3W7F A;  3WJK A;  2E93 A;  4EA0 A;  3BNX A;  4NUA A;  5ILY A;  3S9V A;  2Z4X A;  2Z4W A;  1WL2 A;  2Q80 A;  1WMW A;  2PS5 A;  3WSA A;  1N24 A;  3DYG A;  3SDU A;  4K10 A;  3UCA A;  4Q23 A;  3NF2 A;  3SDT A;  1WKZ A;  2OGD A;  3M01 A;  1YHL A;  3LEE A;  5IN8 A;  2PS6 A;  3ICM A;  3N49 F;  3NPR A;  1N21 A;  1UBW A;  1V4E A;  1HXA A;  2ZCQ A; 
#chains in the Genus database with same CATH topology
 4LIX A;  3M02 A;  5IKH A;  4OGU A;  1V4K A;  3DYF A;  1YV5 A;  2E8U A;  3N3D A;  3CKE A;  2AEL A;  3OYR A;  3Q1O A;  5DHK A;  4LZ3 A;  1FPS A;  2Q58 A;  4FP4 A;  2I19 A;  3N0G A;  3KRA B;  4QXS F;  4PVY F;  5ILK A;  4N9U A;  2ZCS A;  2AZK A;  3BNY A;  4EA2 A;  4KQ5 A;  5B03 A;  2F89 F;  5E8L A;  1JFG A;  4NKE A;  5DZ2 A;  3WJO A;  2PS7 A;  1KIY A;  4XQT F;  3P8R A;  4L2X F;  3WEI A;  4LPH F;  1HM7 A;  2ONG A;  1YYQ A;  5E8K A;  2DH4 A;  5IL3 A;  1HXC A;  3TFV A;  3WCL A;  3S4J A;  5DIQ F;  4E1E A;  3ID0 A;  3WEG A;  4UMJ A;  1YHK A;  4GA3 A;  5B0L A;  1DGP A;  4NFK F;  1YJ4 A;  5IM1 A;  3KRF A;  4H5C F;  3RYE A;  3Q30 A;  2Z4Y A;  3N5J F;  3V66 A;  3VJE A;  4NG6 A;  5ILZ A;  4N1Z F;  2ZCO A;  3WCF A;  4QPF A;  5JA0 F;  3ADZ A;  5ER8 A;  4LA6 A;  4JVJ F;  2Z78 A;  3M0G A;  2E8X A;  3LJI A;  3PKO A;  5AHU B;  4LA5 A;  4RXC A;  1HM4 A;  4KVI A;  3N6K F;  5DJV F;  3KRO A;  3ICK A;  2VF6 A;  2Z7I A;  5DGM F;  4LXW A;  3VJA A;  4FJQ A;  2FTZ A;  4RNQ A;  2P1C A;  1HX9 A;  3LZ9 A;  3KRP A;  5AYP A;  3ACX A;  5ILD A;  4LZC A;  4RXA A;  3ZMC A;  2E4O A;  4KVW A;  4JYX A;  1WL1 A;  5A0J A;  3EZ3 A;  1RQJ A;  4NFJ F;  5ILI A;  5DJR F;  2J1O A;  3WC9 A;  4E9Z A;  3VJC A;  3V1X A;  2FOR A;  2J1P A;  3OAB A;  3QQV A;  4MC3 A;  3WJN A;  2OPM A;  5B0K A;  3M9U A;  4P0X A;  4PVX F;  3DYH A;  4RXD A;  2ZEU A;  3P41 A;  2F8C F;  4JZB A;  4P0W A;  2H8O A;  4GP2 A;  4P0V A;  4F6V A;  5DW7 A;  4KK2 A;  3G4D A;  4LTZ A;  2E8W A;  3SAE A;  3WCC A;  3CP6 A;  1N23 A;  4EA1 A;  3OAC A;  1YHM A;  2ONH A;  1ZW5 A;  4JXN A;  2Z50 A;  2F92 F;  3ZCD A;  5IVG A;  4NFI F;  3RMG A;  5ERM A;  1WL3 A;  3KRF B;  5DGN F;  2Q9Y A;  3V1V A;  5HN9 A;  1RTR A;  4LUU A;  5B00 A;  4DEM F;  1YYT A;  4LLS A;  4OKM A;  4KPJ A;  4KQS A;  3B7L A;  4LZ0 A;  1HXG A;  2F94 F;  2E91 A;  4DI5 A;  1UBX A;  4XQR F;  1YYS A;  5B0J A;  3WCI A;  3LSN A;  1VG2 A;  5I1U A;  3LG5 A;  5AFX A;  3ICN A;  1YYR A;  1N1B A;  3KBK A;  4LFE A;  2PS8 A;  1PS1 A;  3ZL6 A;  5B01 A;  3N46 F;  4HD1 A;  5JV0 F;  3KRP B;  1V4I A;  4NKF A;  3AQC B;  3KB9 A;  3WCH A;  2AZL A;  3MAV A;  3LGZ B;  5A0K A;  1VG3 A;  3N0F A;  4DXJ A;  3RBM A;  3PYB A;  4RYP A;  3WCD A;  2F8Z F;  1VG6 A;  5CG6 A;  4MC8 A;  1JFA A;  5IMN A;  2F7M F;  3NRI A;  3TFN A;  4KFA A;  5EAS A;  3LMD A;  3CC9 A;  3WEF A;  5JUZ F;  3IBA A;  1YYU A;  3OAB B;  5HNA A;  2ZEV A;  5HN8 A;  2F9K F;  2E95 A;  3QKC A;  2OA6 A;  4OKZ A;  1WY0 A;  2Q9Z A;  4RXE A;  3LVS A;  1V4H A;  4H5E F;  3LK5 A;  2AEK A;  3ZMB A;  5IMP A;  2O1O A;  4DHD A;  3ACW A;  1UBV A;  3N3L F;  4WK5 A;  2OPN A;  2Z4V A;  3WEK A;  4LFV F;  3ICZ A;  3PH7 A;  3Q2Q A;  5DJP F;  3WCG A;  3OAC B;  3VJ9 A;  3TS7 A;  5E8H A;  5JV1 F;  3WCE A;  5B0M A;  3KRC A;  3MZV A;  1N1Z A;  2AET A;  2Z7H A;  3WSB A;  3VJD A;  4KPD A;  3N5H F;  3LLW A;  4ZQ8 A;  4KUX A;  3SDR A;  2Z4Z A;  5A0I A;  2E94 A;  3LGK A;  4F62 A;  5IK9 A;  4KQU A;  2E92 A;  3ASX A;  1N22 A;  1YQ7 A;  3TC1 A;  3APZ A;  5IMI A;  4MC0 A;  4KKM A;  5CG5 A;  1EZF A;  1DI1 A;  2EWG A;  2AZJ A;  3WCM A;  2Z52 A;  3LDW A;  3EGT A;  5B02 A;  4KWD A;  2E90 A;  1UBY A;  4DWB A;  3P8L A;  3G4F A;  5DHI A;  3WCA A;  3N1W F;  3VJB A;  5B0I A;  5IL8 A;  3WCJ A;  5ILJ A;  3ACY A;  4LPG F;  1VG4 A;  2RAH A;  5IK6 A;  3ZOU A;  5IKA A;  4LLT A;  2J5C A;  3RYW A;  4LTV A;  5KSX F;  3AQB B;  4E9U A;  2ZCR A;  4H5D F;  4GP1 A;  3AQ0 A;  3PDE A;  3SDQ A;  3KRO B;  5EAT A;  3WE9 A;  5ERO A;  4LFG A;  4KVD A;  1V4J A;  4XQS F;  3SDV A;  4OMG A;  3N45 F;  3P5P A;  3WCB A;  5IK0 A;  5AEL A;  5JV2 F;  3LOM A;  1VG7 A;  3WEH A;  5ILH A;  4DWG A;  5DGS F;  3KRA A;  2E8V A;  4KVY A;  2E8T A;  4JZX A;  3N1V F;  5C05 A;  3AE0 A;  3VJ8 A;  4GAX A;  4LOB A;  3TFP A;  5H9D A;  3EFQ A;  3KRC B;  5HN7 A;  3Q2Z A;  3IPI A;  4JXY A;  3M00 A;  1RQI A;  2ZY1 A;  3P5R A;  4F6X A;  2QIS A;  1WL0 A;  5ERN A;  2PS4 A;  3WEJ A;  4OMH A;  1N20 A;  3PYA A;  5EAU A;  4DZW A;  3NPK A;  1KIZ A;  3W7F A;  3WJK A;  2E93 A;  4EA0 A;  3BNX A;  4NUA A;  5ILY A;  3S9V A;  2Z4X A;  2Z4W A;  1WL2 A;  2Q80 A;  1WMW A;  2PS5 A;  3WSA A;  1N24 A;  3DYG A;  3SDU A;  4K10 A;  3UCA A;  4Q23 A;  3NF2 A;  3SDT A;  1WKZ A;  2OGD A;  3M01 A;  1YHL A;  3LEE A;  5IN8 A;  2PS6 A;  3ICM A;  3N49 F;  3NPR A;  1N21 A;  1UBW A;  1V4E A;  1HXA A;  2ZCQ A; 
#chains in the Genus database with same CATH homology
 4LIX A;  3M02 A;  5IKH A;  4OGU A;  1V4K A;  3DYF A;  1YV5 A;  2E8U A;  3N3D A;  3CKE A;  2AEL A;  3OYR A;  3Q1O A;  5DHK A;  4LZ3 A;  1FPS A;  2Q58 A;  4FP4 A;  2I19 A;  3N0G A;  3KRA B;  4QXS F;  4PVY F;  5ILK A;  4N9U A;  2ZCS A;  2AZK A;  3BNY A;  4EA2 A;  4KQ5 A;  5B03 A;  2F89 F;  5E8L A;  1JFG A;  4NKE A;  5DZ2 A;  3WJO A;  2PS7 A;  1KIY A;  4XQT F;  3P8R A;  4L2X F;  3WEI A;  4LPH F;  1HM7 A;  2ONG A;  1YYQ A;  5E8K A;  2DH4 A;  5IL3 A;  1HXC A;  3TFV A;  3WCL A;  3S4J A;  5DIQ F;  4E1E A;  3ID0 A;  3WEG A;  4UMJ A;  1YHK A;  4GA3 A;  5B0L A;  1DGP A;  4NFK F;  1YJ4 A;  5IM1 A;  3KRF A;  4H5C F;  3RYE A;  3Q30 A;  2Z4Y A;  3N5J F;  3V66 A;  3VJE A;  4NG6 A;  5ILZ A;  4N1Z F;  2ZCO A;  3WCF A;  4QPF A;  5JA0 F;  3ADZ A;  5ER8 A;  4LA6 A;  4JVJ F;  2Z78 A;  3M0G A;  2E8X A;  3LJI A;  3PKO A;  5AHU B;  4LA5 A;  4RXC A;  1HM4 A;  4KVI A;  3N6K F;  5DJV F;  3KRO A;  3ICK A;  2VF6 A;  2Z7I A;  5DGM F;  4LXW A;  3VJA A;  4FJQ A;  2FTZ A;  4RNQ A;  2P1C A;  1HX9 A;  3LZ9 A;  3KRP A;  5AYP A;  3ACX A;  5ILD A;  4LZC A;  4RXA A;  3ZMC A;  2E4O A;  4KVW A;  4JYX A;  1WL1 A;  5A0J A;  3EZ3 A;  1RQJ A;  4NFJ F;  5ILI A;  5DJR F;  2J1O A;  3WC9 A;  4E9Z A;  3VJC A;  3V1X A;  2FOR A;  2J1P A;  3OAB A;  3QQV A;  4MC3 A;  3WJN A;  2OPM A;  5B0K A;  3M9U A;  4P0X A;  4PVX F;  3DYH A;  4RXD A;  2ZEU A;  3P41 A;  2F8C F;  4JZB A;  4P0W A;  2H8O A;  4GP2 A;  4P0V A;  4F6V A;  5DW7 A;  4KK2 A;  3G4D A;  4LTZ A;  2E8W A;  3SAE A;  3WCC A;  3CP6 A;  1N23 A;  4EA1 A;  3OAC A;  1YHM A;  2ONH A;  1ZW5 A;  4JXN A;  2Z50 A;  2F92 F;  3ZCD A;  5IVG A;  4NFI F;  3RMG A;  5ERM A;  1WL3 A;  3KRF B;  5DGN F;  2Q9Y A;  3V1V A;  5HN9 A;  1RTR A;  4LUU A;  5B00 A;  4DEM F;  1YYT A;  4LLS A;  4OKM A;  4KPJ A;  4KQS A;  3B7L A;  4LZ0 A;  1HXG A;  2F94 F;  2E91 A;  4DI5 A;  1UBX A;  4XQR F;  1YYS A;  5B0J A;  3WCI A;  3LSN A;  1VG2 A;  5I1U A;  3LG5 A;  5AFX A;  3ICN A;  1YYR A;  1N1B A;  3KBK A;  4LFE A;  2PS8 A;  1PS1 A;  3ZL6 A;  5B01 A;  3N46 F;  4HD1 A;  5JV0 F;  3KRP B;  1V4I A;  4NKF A;  3AQC B;  3KB9 A;  3WCH A;  2AZL A;  3MAV A;  3LGZ B;  5A0K A;  1VG3 A;  3N0F A;  4DXJ A;  3RBM A;  3PYB A;  4RYP A;  3WCD A;  2F8Z F;  1VG6 A;  5CG6 A;  4MC8 A;  1JFA A;  5IMN A;  2F7M F;  3NRI A;  3TFN A;  4KFA A;  5EAS A;  3LMD A;  3CC9 A;  3WEF A;  5JUZ F;  3IBA A;  1YYU A;  3OAB B;  5HNA A;  2ZEV A;  5HN8 A;  2F9K F;  2E95 A;  3QKC A;  2OA6 A;  4OKZ A;  1WY0 A;  2Q9Z A;  4RXE A;  3LVS A;  1V4H A;  4H5E F;  3LK5 A;  2AEK A;  3ZMB A;  5IMP A;  2O1O A;  4DHD A;  3ACW A;  1UBV A;  3N3L F;  4WK5 A;  2OPN A;  2Z4V A;  3WEK A;  4LFV F;  3ICZ A;  3PH7 A;  3Q2Q A;  5DJP F;  3WCG A;  3OAC B;  3VJ9 A;  3TS7 A;  5E8H A;  5JV1 F;  3WCE A;  5B0M A;  3KRC A;  3MZV A;  1N1Z A;  2AET A;  2Z7H A;  3WSB A;  3VJD A;  4KPD A;  3N5H F;  3LLW A;  4ZQ8 A;  4KUX A;  3SDR A;  2Z4Z A;  5A0I A;  2E94 A;  3LGK A;  4F62 A;  5IK9 A;  4KQU A;  2E92 A;  3ASX A;  1N22 A;  1YQ7 A;  3TC1 A;  3APZ A;  5IMI A;  4MC0 A;  4KKM A;  5CG5 A;  1EZF A;  1DI1 A;  2EWG A;  2AZJ A;  3WCM A;  2Z52 A;  3LDW A;  3EGT A;  5B02 A;  4KWD A;  2E90 A;  1UBY A;  4DWB A;  3P8L A;  3G4F A;  5DHI A;  3WCA A;  3N1W F;  3VJB A;  5B0I A;  5IL8 A;  3WCJ A;  5ILJ A;  3ACY A;  4LPG F;  1VG4 A;  2RAH A;  5IK6 A;  3ZOU A;  5IKA A;  4LLT A;  2J5C A;  3RYW A;  4LTV A;  5KSX F;  3AQB B;  4E9U A;  2ZCR A;  4H5D F;  4GP1 A;  3AQ0 A;  3PDE A;  3SDQ A;  3KRO B;  5EAT A;  3WE9 A;  5ERO A;  4LFG A;  4KVD A;  1V4J A;  4XQS F;  3SDV A;  4OMG A;  3N45 F;  3P5P A;  3WCB A;  5IK0 A;  5AEL A;  5JV2 F;  3LOM A;  1VG7 A;  3WEH A;  5ILH A;  4DWG A;  5DGS F;  3KRA A;  2E8V A;  4KVY A;  2E8T A;  4JZX A;  3N1V F;  5C05 A;  3AE0 A;  3VJ8 A;  4GAX A;  4LOB A;  3TFP A;  5H9D A;  3EFQ A;  3KRC B;  5HN7 A;  3Q2Z A;  3IPI A;  4JXY A;  3M00 A;  1RQI A;  2ZY1 A;  3P5R A;  4F6X A;  2QIS A;  1WL0 A;  5ERN A;  2PS4 A;  3WEJ A;  4OMH A;  1N20 A;  3PYA A;  5EAU A;  4DZW A;  3NPK A;  1KIZ A;  3W7F A;  3WJK A;  2E93 A;  4EA0 A;  3BNX A;  4NUA A;  5ILY A;  3S9V A;  2Z4X A;  2Z4W A;  1WL2 A;  2Q80 A;  1WMW A;  2PS5 A;  3WSA A;  1N24 A;  3DYG A;  3SDU A;  4K10 A;  3UCA A;  4Q23 A;  3NF2 A;  3SDT A;  1WKZ A;  2OGD A;  3M01 A;  1YHL A;  3LEE A;  5IN8 A;  2PS6 A;  3ICM A;  3N49 F;  3NPR A;  1N21 A;  1UBW A;  1V4E A;  1HXA A;  2ZCQ A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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