4PVXF

Crystal structure of human fpps in complex with [({4-[4-(cyclopropyloxy)phenyl]pyridin-2-yl}amino)methanediyl]bis(phosphonic acid)
Total Genus 134
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
134
sequence length
343
structure length
343
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Transferase/transferase inhibitor
molecule keywords Farnesyl pyrophosphate synthase
publication title Crystallographic and thermodynamic characterization of phenylaminopyridine bisphosphonates binding to human farnesyl pyrophosphate synthase.
pubmed doi rcsb
source organism Homo sapiens
total genus 134
structure length 343
sequence length 343
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2014-03-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4pvxF00
4WK5A 2E8XA 4RNQA 5B0KA 3KRFA 1KIYA 3P8RA 5DHKA 1YYUA 3AQ0A 4LLSA 3VJAA 2OPNA 4E9ZA 4KVIA 2E91A 5JV0F 5IMIA 5B01A 4H5EF 4OMHA 5B0JA 3OACA 1VG6A 1WL2A 1N24A 3P41A 3AQCB 5B0IA 5AELA 3LEEA 5AYPA 3VJ9A 2PS6A 3WCAA 3SDVA 3ACYA 5DIQF 2OA6A 1HM7A 1VG2A 3BNXA 2AZLA 4LZ3A 5IK6A 2E94A 1YQ7A 3N49F 2ZCSA 2EWGA 3PYBA 3P5RA 1VG7A 3ICKA 3N0GA 2Q80A 3KRFB 4EA2A 3P5PA 4OGUA 3TC1A 3WCHA 3ZCDA 5ILDA 3KB9A 3B7LA 3LZ9A 3TFPA 3WEGA 3SDTA 1ZW5A 5B0LA 4GA3A 1WL3A 4KVDA 5EAUA 2AZJA 3TS7A 3KRPA 3N0FA 3WSBA 2ZEVA 3CKEA 5DZ2A 5B02A 2F92F 3VJEA 1FPSA 3WCGA 3ACWA 2E92A 5AHUB 5HNAA 4LUUA 3SDQA 5ERNA 4XQSF 3Q2ZA 3P8LA 5IKAA 2AEKA 1HXCA 4KFAA 3LVSA 5IKHA 5IVGA 3N6KF 3DYHA 3WCEA 2J5CA 3NF2A 3WEFA 3DYFA 5DJPF 4KQUA 4LA5A 1YYQA 4QPFA 1YYRA 3QKCA 2DH4A 1EZFA 2Z52A 5ILHA 3IPIA 3WJOA 2E8WA 4LTVA 3N1VF 3OYRA 2PS5A 1HX9A 3WEKA 3LSNA 3MAVA 3SAEA 3KRPB 3EZ3A 1RQIA 4LXWA 3CP6A 3RMGA 3WCCA 3LGKA 3NPRA 4N9UA 1YHMA 1JFAA 3M00A 3ACXA 4E1EA 4DZWA 5JA0F 1N22A 2Z7IA 4ZQ8A 5EASA 2E95A 2AELA 4FP4A 2ZEUA 5ILJA 2VF6A 3KBKA 4DEMF 3WCJA 1YHLA 4KVWA 4XQRF 3G4FA 5B0MA 1DI1A 1VG4A 5E8HA 3N1WF 5IMNA 5DGNF 3ZMBA 4F6XA 4DWGA 4LPGF 3WCLA 2AETA 4P0VA 5ERMA 5JV1F 5ILKA 4FJQA 4LFGA 5ER8A 4LZ0A 5ILYA 1RQJA 3UCAA 4KWDA 3SDRA 5IL3A 3MZVA 5A0IA 5ILIA 2J1PA 5DHIA 3WEHA 3M9UA 5IM1A 4H5CF 4JZXA 1JFGA 4LPHF 4DHDA 3S4JA 3WCFA 3LMDA 1PS1A 2ZY1A 4QXSF 2Z4YA 3TFVA 2QISA 1KIZA 3PKOA 4LFVF 4LZCA 4K10A 3VJBA 3V66A 2ONGA 3WCMA 3IBAA 4XQTF 3OACB 3LG5A 4E9UA 2Z7HA 5A0KA 3WE9A 2Z50A 3ICMA 5IMPA 3M0GA 3WCBA 1UBYA 5A0JA 1V4KA 1YJ4A 1HXGA 5KSXF 4JXNA 2O1OA 4GP2A 2F8CF 2J1OA 3PYAA 4LTZA 5IK0A 3RYWA 2Q9ZA 3PDEA 1VG3A 2F89F 3EGTA 4EA0A 4P0XA 2Z4WA 1N20A 2P1CA 3KROA 4RXCA 3SDUA 3N5HF 4P0WA 5HN8A 2F8ZF 2FORA 3ADZA 3ID0A 4DWBA 2ZCQA 3ASXA 1N1ZA 1YYSA 3KRAA 4KQSA 2E8VA 3VJCA 1UBXA 4H5DF 2H8OA 3NPKA 4NFKF 1YHKA 2ONHA 4RXAA 4DXJA 1YYTA 3WJNA 4GAXA 3N5JF 3VJ8A 3AE0A 2E93A 2E90A 3WCIA 3Q1OA 3WC9A 3RBMA 4OMGA 4HD1A 3ICNA 4NFIF 3DYGA 1RTRA 4NKEA 4RYPA 3KROB 3BNYA 3N3DA 3ZMCA 4KUXA 3N45F 3PH7A 4JXYA 2E8TA 4LFEA 4LA6A 3AQBB 3S9VA 2Z4ZA 2Z4XA 4GP1A 5EATA 3VJDA 3KRAB 3ZOUA 4RXDA 4UMJA 4PVYF 3QQVA 3N3LF 5CG6A 5DJVF 1WMWA 3M01A 1WY0A 3OABA 5B03A 3WEIA 4KPJA 5E8KA 3G4DA 5JUZF 4MC3A 3WEJA 1V4EA 3ICZA 2ZCRA 4PVXF 1V4IA 5IN8A 1N21A 5DJRF 3EFQA 2F7MF 4OKMA 1N1BA 3LDWA 3WJKA 4N1ZF 4MC0A 5HN7A 1DGPA 4EA1A 2Z4VA 5DGSF 1WL0A 3LLWA 3LK5A 3M02A 4KKMA 3W7FA 3WSAA 5HN9A 1WKZA 3RYEA 2ZCOA 4NFJF 3APZA 2E4OA 5IL8A 3NRIA 5AFXA 3LGZB 5JV2F 2Q58A 2PS4A 5ILZA 3KRCA 5C05A 5B00A 3OABB 1V4HA 3Q30A 1N23A 2F94F 4JYXA 4F62A 3V1VA 5CG5A 2RAHA 2AZKA 4LOBA 2Q9YA 4JVJF 1UBWA 4KVYA 1UBVA 3Q2QA 4L2XF 4NUAA 5I1UA 4DI5A 2E8UA 5E8LA 4OKZA 4KPDA 2I19A 4NG6A 4KQ5A 4MC8A 3TFNA 2OPMA 2OGDA 4F6VA 4LIXA 4JZBA 1YV5A 3LJIA 3CC9A 3WCDA 2Z78A 1HXAA 3LOMA 4NKFA 4KK2A 2F9KF 5DGMF 2PS7A 2FTZA 3KRCB 4LLTA 1HM4A 3ZL6A 3V1XA 1V4JA 5EROA 1WL1A 4Q23A 4RXEA 5DW7A 3N46F 2PS8A 5IK9A 5H9DA
chains in the Genus database with same CATH superfamily
4WK5A 2E8XA 4RNQA 5B0KA 3KRFA 1KIYA 3P8RA 5DHKA 1YYUA 3AQ0A 4LLSA 3VJAA 2OPNA 4E9ZA 4KVIA 2E91A 5JV0F 5IMIA 5B01A 4H5EF 4OMHA 5B0JA 3OACA 1VG6A 1WL2A 1N24A 3P41A 3AQCB 5B0IA 5AELA 3LEEA 5AYPA 3VJ9A 2PS6A 3WCAA 3SDVA 3ACYA 5DIQF 2OA6A 1HM7A 1VG2A 3BNXA 2AZLA 4LZ3A 5IK6A 2E94A 1YQ7A 3N49F 2ZCSA 2EWGA 3PYBA 3P5RA 1VG7A 3ICKA 3N0GA 2Q80A 3KRFB 4EA2A 3P5PA 4OGUA 3TC1A 3WCHA 3ZCDA 5ILDA 3KB9A 3B7LA 3LZ9A 3TFPA 3WEGA 3SDTA 1ZW5A 5B0LA 4GA3A 1WL3A 4KVDA 5EAUA 2AZJA 3TS7A 3KRPA 3N0FA 3WSBA 2ZEVA 3CKEA 5DZ2A 5B02A 2F92F 3VJEA 1FPSA 3WCGA 3ACWA 2E92A 5AHUB 5HNAA 4LUUA 3SDQA 5ERNA 4XQSF 3Q2ZA 3P8LA 5IKAA 2AEKA 1HXCA 4KFAA 3LVSA 5IKHA 5IVGA 3N6KF 3DYHA 3WCEA 2J5CA 3NF2A 3WEFA 3DYFA 5DJPF 4KQUA 4LA5A 1YYQA 4QPFA 1YYRA 3QKCA 2DH4A 1EZFA 2Z52A 5ILHA 3IPIA 3WJOA 2E8WA 4LTVA 3N1VF 3OYRA 2PS5A 1HX9A 3WEKA 3LSNA 3MAVA 3SAEA 3KRPB 3EZ3A 1RQIA 4LXWA 3CP6A 3RMGA 3WCCA 3LGKA 3NPRA 4N9UA 1YHMA 1JFAA 3M00A 3ACXA 4E1EA 4DZWA 5JA0F 1N22A 2Z7IA 4ZQ8A 5EASA 2E95A 2AELA 4FP4A 2ZEUA 5ILJA 2VF6A 3KBKA 4DEMF 3WCJA 1YHLA 4KVWA 4XQRF 3G4FA 5B0MA 1DI1A 1VG4A 5E8HA 3N1WF 5IMNA 5DGNF 3ZMBA 4F6XA 4DWGA 4LPGF 3WCLA 2AETA 4P0VA 5ERMA 5JV1F 5ILKA 4FJQA 4LFGA 5ER8A 4LZ0A 5ILYA 1RQJA 3UCAA 4KWDA 3SDRA 5IL3A 3MZVA 5A0IA 5ILIA 2J1PA 5DHIA 3WEHA 3M9UA 5IM1A 4H5CF 4JZXA 1JFGA 4LPHF 4DHDA 3S4JA 3WCFA 3LMDA 1PS1A 2ZY1A 4QXSF 2Z4YA 3TFVA 2QISA 1KIZA 3PKOA 4LFVF 4LZCA 4K10A 3VJBA 3V66A 2ONGA 3WCMA 3IBAA 4XQTF 3OACB 3LG5A 4E9UA 2Z7HA 5A0KA 3WE9A 2Z50A 3ICMA 5IMPA 3M0GA 3WCBA 1UBYA 5A0JA 1V4KA 1YJ4A 1HXGA 5KSXF 4JXNA 2O1OA 4GP2A 2F8CF 2J1OA 3PYAA 4LTZA 5IK0A 3RYWA 2Q9ZA 3PDEA 1VG3A 2F89F 3EGTA 4EA0A 4P0XA 2Z4WA 1N20A 2P1CA 3KROA 4RXCA 3SDUA 3N5HF 4P0WA 5HN8A 2F8ZF 2FORA 3ADZA 3ID0A 4DWBA 2ZCQA 3ASXA 1N1ZA 1YYSA 3KRAA 4KQSA 2E8VA 3VJCA 1UBXA 4H5DF 2H8OA 3NPKA 4NFKF 1YHKA 2ONHA 4RXAA 4DXJA 1YYTA 3WJNA 4GAXA 3N5JF 3VJ8A 3AE0A 2E93A 2E90A 3WCIA 3Q1OA 3WC9A 3RBMA 4OMGA 4HD1A 3ICNA 4NFIF 3DYGA 1RTRA 4NKEA 4RYPA 3KROB 3BNYA 3N3DA 3ZMCA 4KUXA 3N45F 3PH7A 4JXYA 2E8TA 4LFEA 4LA6A 3AQBB 3S9VA 2Z4ZA 2Z4XA 4GP1A 5EATA 3VJDA 3KRAB 3ZOUA 4RXDA 4UMJA 4PVYF 3QQVA 3N3LF 5CG6A 5DJVF 1WMWA 3M01A 1WY0A 3OABA 5B03A 3WEIA 4KPJA 5E8KA 3G4DA 5JUZF 4MC3A 3WEJA 1V4EA 3ICZA 2ZCRA 4PVXF 1V4IA 5IN8A 1N21A 5DJRF 3EFQA 2F7MF 4OKMA 1N1BA 3LDWA 3WJKA 4N1ZF 4MC0A 5HN7A 1DGPA 4EA1A 2Z4VA 5DGSF 1WL0A 3LLWA 3LK5A 3M02A 4KKMA 3W7FA 3WSAA 5HN9A 1WKZA 3RYEA 2ZCOA 4NFJF 3APZA 2E4OA 5IL8A 3NRIA 5AFXA 3LGZB 5JV2F 2Q58A 2PS4A 5ILZA 3KRCA 5C05A 5B00A 3OABB 1V4HA 3Q30A 1N23A 2F94F 4JYXA 4F62A 3V1VA 5CG5A 2RAHA 2AZKA 4LOBA 2Q9YA 4JVJF 1UBWA 4KVYA 1UBVA 3Q2QA 4L2XF 4NUAA 5I1UA 4DI5A 2E8UA 5E8LA 4OKZA 4KPDA 2I19A 4NG6A 4KQ5A 4MC8A 3TFNA 2OPMA 2OGDA 4F6VA 4LIXA 4JZBA 1YV5A 3LJIA 3CC9A 3WCDA 2Z78A 1HXAA 3LOMA 4NKFA 4KK2A 2F9KF 5DGMF 2PS7A 2FTZA 3KRCB 4LLTA 1HM4A 3ZL6A 3V1XA 1V4JA 5EROA 1WL1A 4Q23A 4RXEA 5DW7A 3N46F 2PS8A 5IK9A 5H9DA
chains in the Genus database with same CATH topology
4WK5A 2E8XA 4RNQA 5B0KA 3KRFA 1KIYA 3P8RA 5DHKA 1YYUA 3AQ0A 4LLSA 3VJAA 2OPNA 4E9ZA 4KVIA 2E91A 5JV0F 5IMIA 5B01A 4H5EF 4OMHA 5B0JA 3OACA 1VG6A 1WL2A 1N24A 3P41A 3AQCB 5B0IA 5AELA 3LEEA 5AYPA 3VJ9A 2PS6A 3WCAA 3SDVA 3ACYA 5DIQF 2OA6A 1HM7A 1VG2A 3BNXA 2AZLA 4LZ3A 5IK6A 2E94A 1YQ7A 3N49F 2ZCSA 2EWGA 3PYBA 3P5RA 1VG7A 3ICKA 3N0GA 2Q80A 3KRFB 4EA2A 3P5PA 4OGUA 3TC1A 3WCHA 3ZCDA 5ILDA 3KB9A 3B7LA 3LZ9A 3TFPA 3WEGA 3SDTA 1ZW5A 5B0LA 4GA3A 1WL3A 4KVDA 5EAUA 2AZJA 3TS7A 3KRPA 3N0FA 3WSBA 2ZEVA 3CKEA 5DZ2A 5B02A 2F92F 3VJEA 1FPSA 3WCGA 3ACWA 2E92A 5AHUB 5HNAA 4LUUA 3SDQA 5ERNA 4XQSF 3Q2ZA 3P8LA 5IKAA 2AEKA 1HXCA 4KFAA 3LVSA 5IKHA 5IVGA 3N6KF 3DYHA 3WCEA 2J5CA 3NF2A 3WEFA 3DYFA 5DJPF 4KQUA 4LA5A 1YYQA 4QPFA 1YYRA 3QKCA 2DH4A 1EZFA 2Z52A 5ILHA 3IPIA 3WJOA 2E8WA 4LTVA 3N1VF 3OYRA 2PS5A 1HX9A 3WEKA 3LSNA 3MAVA 3SAEA 3KRPB 3EZ3A 1RQIA 4LXWA 3CP6A 3RMGA 3WCCA 3LGKA 3NPRA 4N9UA 1YHMA 1JFAA 3M00A 3ACXA 4E1EA 4DZWA 5JA0F 1N22A 2Z7IA 4ZQ8A 5EASA 2E95A 2AELA 4FP4A 2ZEUA 5ILJA 2VF6A 3KBKA 4DEMF 3WCJA 1YHLA 4KVWA 4XQRF 3G4FA 5B0MA 1DI1A 1VG4A 5E8HA 3N1WF 5IMNA 5DGNF 3ZMBA 4F6XA 4DWGA 4LPGF 3WCLA 2AETA 4P0VA 5ERMA 5JV1F 5ILKA 4FJQA 4LFGA 5ER8A 4LZ0A 5ILYA 1RQJA 3UCAA 4KWDA 3SDRA 5IL3A 3MZVA 5A0IA 5ILIA 2J1PA 5DHIA 3WEHA 3M9UA 5IM1A 4H5CF 4JZXA 1JFGA 4LPHF 4DHDA 3S4JA 3WCFA 3LMDA 1PS1A 2ZY1A 4QXSF 2Z4YA 3TFVA 2QISA 1KIZA 3PKOA 4LFVF 4LZCA 4K10A 3VJBA 3V66A 2ONGA 3WCMA 3IBAA 4XQTF 3OACB 3LG5A 4E9UA 2Z7HA 5A0KA 3WE9A 2Z50A 3ICMA 5IMPA 3M0GA 3WCBA 1UBYA 5A0JA 1V4KA 1YJ4A 1HXGA 5KSXF 4JXNA 2O1OA 4GP2A 2F8CF 2J1OA 3PYAA 4LTZA 5IK0A 3RYWA 2Q9ZA 3PDEA 1VG3A 2F89F 3EGTA 4EA0A 4P0XA 2Z4WA 1N20A 2P1CA 3KROA 4RXCA 3SDUA 3N5HF 4P0WA 5HN8A 2F8ZF 2FORA 3ADZA 3ID0A 4DWBA 2ZCQA 3ASXA 1N1ZA 1YYSA 3KRAA 4KQSA 2E8VA 3VJCA 1UBXA 4H5DF 2H8OA 3NPKA 4NFKF 1YHKA 2ONHA 4RXAA 4DXJA 1YYTA 3WJNA 4GAXA 3N5JF 3VJ8A 3AE0A 2E93A 2E90A 3WCIA 3Q1OA 3WC9A 3RBMA 4OMGA 4HD1A 3ICNA 4NFIF 3DYGA 1RTRA 4NKEA 4RYPA 3KROB 3BNYA 3N3DA 3ZMCA 4KUXA 3N45F 3PH7A 4JXYA 2E8TA 4LFEA 4LA6A 3AQBB 3S9VA 2Z4ZA 2Z4XA 4GP1A 5EATA 3VJDA 3KRAB 3ZOUA 4RXDA 4UMJA 4PVYF 3QQVA 3N3LF 5CG6A 5DJVF 1WMWA 3M01A 1WY0A 3OABA 5B03A 3WEIA 4KPJA 5E8KA 3G4DA 5JUZF 4MC3A 3WEJA 1V4EA 3ICZA 2ZCRA 4PVXF 1V4IA 5IN8A 1N21A 5DJRF 3EFQA 2F7MF 4OKMA 1N1BA 3LDWA 3WJKA 4N1ZF 4MC0A 5HN7A 1DGPA 4EA1A 2Z4VA 5DGSF 1WL0A 3LLWA 3LK5A 3M02A 4KKMA 3W7FA 3WSAA 5HN9A 1WKZA 3RYEA 2ZCOA 4NFJF 3APZA 2E4OA 5IL8A 3NRIA 5AFXA 3LGZB 5JV2F 2Q58A 2PS4A 5ILZA 3KRCA 5C05A 5B00A 3OABB 1V4HA 3Q30A 1N23A 2F94F 4JYXA 4F62A 3V1VA 5CG5A 2RAHA 2AZKA 4LOBA 2Q9YA 4JVJF 1UBWA 4KVYA 1UBVA 3Q2QA 4L2XF 4NUAA 5I1UA 4DI5A 2E8UA 5E8LA 4OKZA 4KPDA 2I19A 4NG6A 4KQ5A 4MC8A 3TFNA 2OPMA 2OGDA 4F6VA 4LIXA 4JZBA 1YV5A 3LJIA 3CC9A 3WCDA 2Z78A 1HXAA 3LOMA 4NKFA 4KK2A 2F9KF 5DGMF 2PS7A 2FTZA 3KRCB 4LLTA 1HM4A 3ZL6A 3V1XA 1V4JA 5EROA 1WL1A 4Q23A 4RXEA 5DW7A 3N46F 2PS8A 5IK9A 5H9DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WK5 A;  2E8X A;  4RNQ A;  5B0K A;  3KRF A;  1KIY A;  3P8R A;  5DHK A;  1YYU A;  3AQ0 A;  4LLS A;  3VJA A;  2OPN A;  4E9Z A;  4KVI A;  2E91 A;  5JV0 F;  5IMI A;  5B01 A;  4H5E F;  4OMH A;  5B0J A;  3OAC A;  1VG6 A;  1WL2 A;  1N24 A;  3P41 A;  3AQC B;  5B0I A;  5AEL A;  3LEE A;  5AYP A;  3VJ9 A;  2PS6 A;  3WCA A;  3SDV A;  3ACY A;  5DIQ F;  2OA6 A;  1HM7 A;  1VG2 A;  3BNX A;  2AZL A;  4LZ3 A;  5IK6 A;  2E94 A;  1YQ7 A;  3N49 F;  2ZCS A;  2EWG A;  3PYB A;  3P5R A;  1VG7 A;  3ICK A;  3N0G A;  2Q80 A;  3KRF B;  4EA2 A;  3P5P A;  4OGU A;  3TC1 A;  3WCH A;  3ZCD A;  5ILD A;  3KB9 A;  3B7L A;  3LZ9 A;  3TFP A;  3WEG A;  3SDT A;  1ZW5 A;  5B0L A;  4GA3 A;  1WL3 A;  4KVD A;  5EAU A;  2AZJ A;  3TS7 A;  3KRP A;  3N0F A;  3WSB A;  2ZEV A;  3CKE A;  5DZ2 A;  5B02 A;  2F92 F;  3VJE A;  1FPS A;  3WCG A;  3ACW A;  2E92 A;  5AHU B;  5HNA A;  4LUU A;  3SDQ A;  5ERN A;  4XQS F;  3Q2Z A;  3P8L A;  5IKA A;  2AEK A;  1HXC A;  4KFA A;  3LVS A;  5IKH A;  5IVG A;  3N6K F;  3DYH A;  3WCE A;  2J5C A;  3NF2 A;  3WEF A;  3DYF A;  5DJP F;  4KQU A;  4LA5 A;  1YYQ A;  4QPF A;  1YYR A;  3QKC A;  2DH4 A;  1EZF A;  2Z52 A;  5ILH A;  3IPI A;  3WJO A;  2E8W A;  4LTV A;  3N1V F;  3OYR A;  2PS5 A;  1HX9 A;  3WEK A;  3LSN A;  3MAV A;  3SAE A;  3KRP B;  3EZ3 A;  1RQI A;  4LXW A;  3CP6 A;  3RMG A;  3WCC A;  3LGK A;  3NPR A;  4N9U A;  1YHM A;  1JFA A;  3M00 A;  3ACX A;  4E1E A;  4DZW A;  5JA0 F;  1N22 A;  2Z7I A;  4ZQ8 A;  5EAS A;  2E95 A;  2AEL A;  4FP4 A;  2ZEU A;  5ILJ A;  2VF6 A;  3KBK A;  4DEM F;  3WCJ A;  1YHL A;  4KVW A;  4XQR F;  3G4F A;  5B0M A;  1DI1 A;  1VG4 A;  5E8H A;  3N1W F;  5IMN A;  5DGN F;  3ZMB A;  4F6X A;  4DWG A;  4LPG F;  3WCL A;  2AET A;  4P0V A;  5ERM A;  5JV1 F;  5ILK A;  4FJQ A;  4LFG A;  5ER8 A;  4LZ0 A;  5ILY A;  1RQJ A;  3UCA A;  4KWD A;  3SDR A;  5IL3 A;  3MZV A;  5A0I A;  5ILI A;  2J1P A;  5DHI A;  3WEH A;  3M9U A;  5IM1 A;  4H5C F;  4JZX A;  1JFG A;  4LPH F;  4DHD A;  3S4J A;  3WCF A;  3LMD A;  1PS1 A;  2ZY1 A;  4QXS F;  2Z4Y A;  3TFV A;  2QIS A;  1KIZ A;  3PKO A;  4LFV F;  4LZC A;  4K10 A;  3VJB A;  3V66 A;  2ONG A;  3WCM A;  3IBA A;  4XQT F;  3OAC B;  3LG5 A;  4E9U A;  2Z7H A;  5A0K A;  3WE9 A;  2Z50 A;  3ICM A;  5IMP A;  3M0G A;  3WCB A;  1UBY A;  5A0J A;  1V4K A;  1YJ4 A;  1HXG A;  5KSX F;  4JXN A;  2O1O A;  4GP2 A;  2F8C F;  2J1O A;  3PYA A;  4LTZ A;  5IK0 A;  3RYW A;  2Q9Z A;  3PDE A;  1VG3 A;  2F89 F;  3EGT A;  4EA0 A;  4P0X A;  2Z4W A;  1N20 A;  2P1C A;  3KRO A;  4RXC A;  3SDU A;  3N5H F;  4P0W A;  5HN8 A;  2F8Z F;  2FOR A;  3ADZ A;  3ID0 A;  4DWB A;  2ZCQ A;  3ASX A;  1N1Z A;  1YYS A;  3KRA A;  4KQS A;  2E8V A;  3VJC A;  1UBX A;  4H5D F;  2H8O A;  3NPK A;  4NFK F;  1YHK A;  2ONH A;  4RXA A;  4DXJ A;  1YYT A;  3WJN A;  4GAX A;  3N5J F;  3VJ8 A;  3AE0 A;  2E93 A;  2E90 A;  3WCI A;  3Q1O A;  3WC9 A;  3RBM A;  4OMG A;  4HD1 A;  3ICN A;  4NFI F;  3DYG A;  1RTR A;  4NKE A;  4RYP A;  3KRO B;  3BNY A;  3N3D A;  3ZMC A;  4KUX A;  3N45 F;  3PH7 A;  4JXY A;  2E8T A;  4LFE A;  4LA6 A;  3AQB B;  3S9V A;  2Z4Z A;  2Z4X A;  4GP1 A;  5EAT A;  3VJD A;  3KRA B;  3ZOU A;  4RXD A;  4UMJ A;  4PVY F;  3QQV A;  3N3L F;  5CG6 A;  5DJV F;  1WMW A;  3M01 A;  1WY0 A;  3OAB A;  5B03 A;  3WEI A;  4KPJ A;  5E8K A;  3G4D A;  5JUZ F;  4MC3 A;  3WEJ A;  1V4E A;  3ICZ A;  2ZCR A;  4PVX F;  1V4I A;  5IN8 A;  1N21 A;  5DJR F;  3EFQ A;  2F7M F;  4OKM A;  1N1B A;  3LDW A;  3WJK A;  4N1Z F;  4MC0 A;  5HN7 A;  1DGP A;  4EA1 A;  2Z4V A;  5DGS F;  1WL0 A;  3LLW A;  3LK5 A;  3M02 A;  4KKM A;  3W7F A;  3WSA A;  5HN9 A;  1WKZ A;  3RYE A;  2ZCO A;  4NFJ F;  3APZ A;  2E4O A;  5IL8 A;  3NRI A;  5AFX A;  3LGZ B;  5JV2 F;  2Q58 A;  2PS4 A;  5ILZ A;  3KRC A;  5C05 A;  5B00 A;  3OAB B;  1V4H A;  3Q30 A;  1N23 A;  2F94 F;  4JYX A;  4F62 A;  3V1V A;  5CG5 A;  2RAH A;  2AZK A;  4LOB A;  2Q9Y A;  4JVJ F;  1UBW A;  4KVY A;  1UBV A;  3Q2Q A;  4L2X F;  4NUA A;  5I1U A;  4DI5 A;  2E8U A;  5E8L A;  4OKZ A;  4KPD A;  2I19 A;  4NG6 A;  4KQ5 A;  4MC8 A;  3TFN A;  2OPM A;  2OGD A;  4F6V A;  4LIX A;  4JZB A;  1YV5 A;  3LJI A;  3CC9 A;  3WCD A;  2Z78 A;  1HXA A;  3LOM A;  4NKF A;  4KK2 A;  2F9K F;  5DGM F;  2PS7 A;  2FTZ A;  3KRC B;  4LLT A;  1HM4 A;  3ZL6 A;  3V1X A;  1V4J A;  5ERO A;  1WL1 A;  4Q23 A;  4RXE A;  5DW7 A;  3N46 F;  2PS8 A;  5IK9 A;  5H9D A; 
#chains in the Genus database with same CATH topology
 4WK5 A;  2E8X A;  4RNQ A;  5B0K A;  3KRF A;  1KIY A;  3P8R A;  5DHK A;  1YYU A;  3AQ0 A;  4LLS A;  3VJA A;  2OPN A;  4E9Z A;  4KVI A;  2E91 A;  5JV0 F;  5IMI A;  5B01 A;  4H5E F;  4OMH A;  5B0J A;  3OAC A;  1VG6 A;  1WL2 A;  1N24 A;  3P41 A;  3AQC B;  5B0I A;  5AEL A;  3LEE A;  5AYP A;  3VJ9 A;  2PS6 A;  3WCA A;  3SDV A;  3ACY A;  5DIQ F;  2OA6 A;  1HM7 A;  1VG2 A;  3BNX A;  2AZL A;  4LZ3 A;  5IK6 A;  2E94 A;  1YQ7 A;  3N49 F;  2ZCS A;  2EWG A;  3PYB A;  3P5R A;  1VG7 A;  3ICK A;  3N0G A;  2Q80 A;  3KRF B;  4EA2 A;  3P5P A;  4OGU A;  3TC1 A;  3WCH A;  3ZCD A;  5ILD A;  3KB9 A;  3B7L A;  3LZ9 A;  3TFP A;  3WEG A;  3SDT A;  1ZW5 A;  5B0L A;  4GA3 A;  1WL3 A;  4KVD A;  5EAU A;  2AZJ A;  3TS7 A;  3KRP A;  3N0F A;  3WSB A;  2ZEV A;  3CKE A;  5DZ2 A;  5B02 A;  2F92 F;  3VJE A;  1FPS A;  3WCG A;  3ACW A;  2E92 A;  5AHU B;  5HNA A;  4LUU A;  3SDQ A;  5ERN A;  4XQS F;  3Q2Z A;  3P8L A;  5IKA A;  2AEK A;  1HXC A;  4KFA A;  3LVS A;  5IKH A;  5IVG A;  3N6K F;  3DYH A;  3WCE A;  2J5C A;  3NF2 A;  3WEF A;  3DYF A;  5DJP F;  4KQU A;  4LA5 A;  1YYQ A;  4QPF A;  1YYR A;  3QKC A;  2DH4 A;  1EZF A;  2Z52 A;  5ILH A;  3IPI A;  3WJO A;  2E8W A;  4LTV A;  3N1V F;  3OYR A;  2PS5 A;  1HX9 A;  3WEK A;  3LSN A;  3MAV A;  3SAE A;  3KRP B;  3EZ3 A;  1RQI A;  4LXW A;  3CP6 A;  3RMG A;  3WCC A;  3LGK A;  3NPR A;  4N9U A;  1YHM A;  1JFA A;  3M00 A;  3ACX A;  4E1E A;  4DZW A;  5JA0 F;  1N22 A;  2Z7I A;  4ZQ8 A;  5EAS A;  2E95 A;  2AEL A;  4FP4 A;  2ZEU A;  5ILJ A;  2VF6 A;  3KBK A;  4DEM F;  3WCJ A;  1YHL A;  4KVW A;  4XQR F;  3G4F A;  5B0M A;  1DI1 A;  1VG4 A;  5E8H A;  3N1W F;  5IMN A;  5DGN F;  3ZMB A;  4F6X A;  4DWG A;  4LPG F;  3WCL A;  2AET A;  4P0V A;  5ERM A;  5JV1 F;  5ILK A;  4FJQ A;  4LFG A;  5ER8 A;  4LZ0 A;  5ILY A;  1RQJ A;  3UCA A;  4KWD A;  3SDR A;  5IL3 A;  3MZV A;  5A0I A;  5ILI A;  2J1P A;  5DHI A;  3WEH A;  3M9U A;  5IM1 A;  4H5C F;  4JZX A;  1JFG A;  4LPH F;  4DHD A;  3S4J A;  3WCF A;  3LMD A;  1PS1 A;  2ZY1 A;  4QXS F;  2Z4Y A;  3TFV A;  2QIS A;  1KIZ A;  3PKO A;  4LFV F;  4LZC A;  4K10 A;  3VJB A;  3V66 A;  2ONG A;  3WCM A;  3IBA A;  4XQT F;  3OAC B;  3LG5 A;  4E9U A;  2Z7H A;  5A0K A;  3WE9 A;  2Z50 A;  3ICM A;  5IMP A;  3M0G A;  3WCB A;  1UBY A;  5A0J A;  1V4K A;  1YJ4 A;  1HXG A;  5KSX F;  4JXN A;  2O1O A;  4GP2 A;  2F8C F;  2J1O A;  3PYA A;  4LTZ A;  5IK0 A;  3RYW A;  2Q9Z A;  3PDE A;  1VG3 A;  2F89 F;  3EGT A;  4EA0 A;  4P0X A;  2Z4W A;  1N20 A;  2P1C A;  3KRO A;  4RXC A;  3SDU A;  3N5H F;  4P0W A;  5HN8 A;  2F8Z F;  2FOR A;  3ADZ A;  3ID0 A;  4DWB A;  2ZCQ A;  3ASX A;  1N1Z A;  1YYS A;  3KRA A;  4KQS A;  2E8V A;  3VJC A;  1UBX A;  4H5D F;  2H8O A;  3NPK A;  4NFK F;  1YHK A;  2ONH A;  4RXA A;  4DXJ A;  1YYT A;  3WJN A;  4GAX A;  3N5J F;  3VJ8 A;  3AE0 A;  2E93 A;  2E90 A;  3WCI A;  3Q1O A;  3WC9 A;  3RBM A;  4OMG A;  4HD1 A;  3ICN A;  4NFI F;  3DYG A;  1RTR A;  4NKE A;  4RYP A;  3KRO B;  3BNY A;  3N3D A;  3ZMC A;  4KUX A;  3N45 F;  3PH7 A;  4JXY A;  2E8T A;  4LFE A;  4LA6 A;  3AQB B;  3S9V A;  2Z4Z A;  2Z4X A;  4GP1 A;  5EAT A;  3VJD A;  3KRA B;  3ZOU A;  4RXD A;  4UMJ A;  4PVY F;  3QQV A;  3N3L F;  5CG6 A;  5DJV F;  1WMW A;  3M01 A;  1WY0 A;  3OAB A;  5B03 A;  3WEI A;  4KPJ A;  5E8K A;  3G4D A;  5JUZ F;  4MC3 A;  3WEJ A;  1V4E A;  3ICZ A;  2ZCR A;  4PVX F;  1V4I A;  5IN8 A;  1N21 A;  5DJR F;  3EFQ A;  2F7M F;  4OKM A;  1N1B A;  3LDW A;  3WJK A;  4N1Z F;  4MC0 A;  5HN7 A;  1DGP A;  4EA1 A;  2Z4V A;  5DGS F;  1WL0 A;  3LLW A;  3LK5 A;  3M02 A;  4KKM A;  3W7F A;  3WSA A;  5HN9 A;  1WKZ A;  3RYE A;  2ZCO A;  4NFJ F;  3APZ A;  2E4O A;  5IL8 A;  3NRI A;  5AFX A;  3LGZ B;  5JV2 F;  2Q58 A;  2PS4 A;  5ILZ A;  3KRC A;  5C05 A;  5B00 A;  3OAB B;  1V4H A;  3Q30 A;  1N23 A;  2F94 F;  4JYX A;  4F62 A;  3V1V A;  5CG5 A;  2RAH A;  2AZK A;  4LOB A;  2Q9Y A;  4JVJ F;  1UBW A;  4KVY A;  1UBV A;  3Q2Q A;  4L2X F;  4NUA A;  5I1U A;  4DI5 A;  2E8U A;  5E8L A;  4OKZ A;  4KPD A;  2I19 A;  4NG6 A;  4KQ5 A;  4MC8 A;  3TFN A;  2OPM A;  2OGD A;  4F6V A;  4LIX A;  4JZB A;  1YV5 A;  3LJI A;  3CC9 A;  3WCD A;  2Z78 A;  1HXA A;  3LOM A;  4NKF A;  4KK2 A;  2F9K F;  5DGM F;  2PS7 A;  2FTZ A;  3KRC B;  4LLT A;  1HM4 A;  3ZL6 A;  3V1X A;  1V4J A;  5ERO A;  1WL1 A;  4Q23 A;  4RXE A;  5DW7 A;  3N46 F;  2PS8 A;  5IK9 A;  5H9D A; 
#chains in the Genus database with same CATH homology
 4WK5 A;  2E8X A;  4RNQ A;  5B0K A;  3KRF A;  1KIY A;  3P8R A;  5DHK A;  1YYU A;  3AQ0 A;  4LLS A;  3VJA A;  2OPN A;  4E9Z A;  4KVI A;  2E91 A;  5JV0 F;  5IMI A;  5B01 A;  4H5E F;  4OMH A;  5B0J A;  3OAC A;  1VG6 A;  1WL2 A;  1N24 A;  3P41 A;  3AQC B;  5B0I A;  5AEL A;  3LEE A;  5AYP A;  3VJ9 A;  2PS6 A;  3WCA A;  3SDV A;  3ACY A;  5DIQ F;  2OA6 A;  1HM7 A;  1VG2 A;  3BNX A;  2AZL A;  4LZ3 A;  5IK6 A;  2E94 A;  1YQ7 A;  3N49 F;  2ZCS A;  2EWG A;  3PYB A;  3P5R A;  1VG7 A;  3ICK A;  3N0G A;  2Q80 A;  3KRF B;  4EA2 A;  3P5P A;  4OGU A;  3TC1 A;  3WCH A;  3ZCD A;  5ILD A;  3KB9 A;  3B7L A;  3LZ9 A;  3TFP A;  3WEG A;  3SDT A;  1ZW5 A;  5B0L A;  4GA3 A;  1WL3 A;  4KVD A;  5EAU A;  2AZJ A;  3TS7 A;  3KRP A;  3N0F A;  3WSB A;  2ZEV A;  3CKE A;  5DZ2 A;  5B02 A;  2F92 F;  3VJE A;  1FPS A;  3WCG A;  3ACW A;  2E92 A;  5AHU B;  5HNA A;  4LUU A;  3SDQ A;  5ERN A;  4XQS F;  3Q2Z A;  3P8L A;  5IKA A;  2AEK A;  1HXC A;  4KFA A;  3LVS A;  5IKH A;  5IVG A;  3N6K F;  3DYH A;  3WCE A;  2J5C A;  3NF2 A;  3WEF A;  3DYF A;  5DJP F;  4KQU A;  4LA5 A;  1YYQ A;  4QPF A;  1YYR A;  3QKC A;  2DH4 A;  1EZF A;  2Z52 A;  5ILH A;  3IPI A;  3WJO A;  2E8W A;  4LTV A;  3N1V F;  3OYR A;  2PS5 A;  1HX9 A;  3WEK A;  3LSN A;  3MAV A;  3SAE A;  3KRP B;  3EZ3 A;  1RQI A;  4LXW A;  3CP6 A;  3RMG A;  3WCC A;  3LGK A;  3NPR A;  4N9U A;  1YHM A;  1JFA A;  3M00 A;  3ACX A;  4E1E A;  4DZW A;  5JA0 F;  1N22 A;  2Z7I A;  4ZQ8 A;  5EAS A;  2E95 A;  2AEL A;  4FP4 A;  2ZEU A;  5ILJ A;  2VF6 A;  3KBK A;  4DEM F;  3WCJ A;  1YHL A;  4KVW A;  4XQR F;  3G4F A;  5B0M A;  1DI1 A;  1VG4 A;  5E8H A;  3N1W F;  5IMN A;  5DGN F;  3ZMB A;  4F6X A;  4DWG A;  4LPG F;  3WCL A;  2AET A;  4P0V A;  5ERM A;  5JV1 F;  5ILK A;  4FJQ A;  4LFG A;  5ER8 A;  4LZ0 A;  5ILY A;  1RQJ A;  3UCA A;  4KWD A;  3SDR A;  5IL3 A;  3MZV A;  5A0I A;  5ILI A;  2J1P A;  5DHI A;  3WEH A;  3M9U A;  5IM1 A;  4H5C F;  4JZX A;  1JFG A;  4LPH F;  4DHD A;  3S4J A;  3WCF A;  3LMD A;  1PS1 A;  2ZY1 A;  4QXS F;  2Z4Y A;  3TFV A;  2QIS A;  1KIZ A;  3PKO A;  4LFV F;  4LZC A;  4K10 A;  3VJB A;  3V66 A;  2ONG A;  3WCM A;  3IBA A;  4XQT F;  3OAC B;  3LG5 A;  4E9U A;  2Z7H A;  5A0K A;  3WE9 A;  2Z50 A;  3ICM A;  5IMP A;  3M0G A;  3WCB A;  1UBY A;  5A0J A;  1V4K A;  1YJ4 A;  1HXG A;  5KSX F;  4JXN A;  2O1O A;  4GP2 A;  2F8C F;  2J1O A;  3PYA A;  4LTZ A;  5IK0 A;  3RYW A;  2Q9Z A;  3PDE A;  1VG3 A;  2F89 F;  3EGT A;  4EA0 A;  4P0X A;  2Z4W A;  1N20 A;  2P1C A;  3KRO A;  4RXC A;  3SDU A;  3N5H F;  4P0W A;  5HN8 A;  2F8Z F;  2FOR A;  3ADZ A;  3ID0 A;  4DWB A;  2ZCQ A;  3ASX A;  1N1Z A;  1YYS A;  3KRA A;  4KQS A;  2E8V A;  3VJC A;  1UBX A;  4H5D F;  2H8O A;  3NPK A;  4NFK F;  1YHK A;  2ONH A;  4RXA A;  4DXJ A;  1YYT A;  3WJN A;  4GAX A;  3N5J F;  3VJ8 A;  3AE0 A;  2E93 A;  2E90 A;  3WCI A;  3Q1O A;  3WC9 A;  3RBM A;  4OMG A;  4HD1 A;  3ICN A;  4NFI F;  3DYG A;  1RTR A;  4NKE A;  4RYP A;  3KRO B;  3BNY A;  3N3D A;  3ZMC A;  4KUX A;  3N45 F;  3PH7 A;  4JXY A;  2E8T A;  4LFE A;  4LA6 A;  3AQB B;  3S9V A;  2Z4Z A;  2Z4X A;  4GP1 A;  5EAT A;  3VJD A;  3KRA B;  3ZOU A;  4RXD A;  4UMJ A;  4PVY F;  3QQV A;  3N3L F;  5CG6 A;  5DJV F;  1WMW A;  3M01 A;  1WY0 A;  3OAB A;  5B03 A;  3WEI A;  4KPJ A;  5E8K A;  3G4D A;  5JUZ F;  4MC3 A;  3WEJ A;  1V4E A;  3ICZ A;  2ZCR A;  4PVX F;  1V4I A;  5IN8 A;  1N21 A;  5DJR F;  3EFQ A;  2F7M F;  4OKM A;  1N1B A;  3LDW A;  3WJK A;  4N1Z F;  4MC0 A;  5HN7 A;  1DGP A;  4EA1 A;  2Z4V A;  5DGS F;  1WL0 A;  3LLW A;  3LK5 A;  3M02 A;  4KKM A;  3W7F A;  3WSA A;  5HN9 A;  1WKZ A;  3RYE A;  2ZCO A;  4NFJ F;  3APZ A;  2E4O A;  5IL8 A;  3NRI A;  5AFX A;  3LGZ B;  5JV2 F;  2Q58 A;  2PS4 A;  5ILZ A;  3KRC A;  5C05 A;  5B00 A;  3OAB B;  1V4H A;  3Q30 A;  1N23 A;  2F94 F;  4JYX A;  4F62 A;  3V1V A;  5CG5 A;  2RAH A;  2AZK A;  4LOB A;  2Q9Y A;  4JVJ F;  1UBW A;  4KVY A;  1UBV A;  3Q2Q A;  4L2X F;  4NUA A;  5I1U A;  4DI5 A;  2E8U A;  5E8L A;  4OKZ A;  4KPD A;  2I19 A;  4NG6 A;  4KQ5 A;  4MC8 A;  3TFN A;  2OPM A;  2OGD A;  4F6V A;  4LIX A;  4JZB A;  1YV5 A;  3LJI A;  3CC9 A;  3WCD A;  2Z78 A;  1HXA A;  3LOM A;  4NKF A;  4KK2 A;  2F9K F;  5DGM F;  2PS7 A;  2FTZ A;  3KRC B;  4LLT A;  1HM4 A;  3ZL6 A;  3V1X A;  1V4J A;  5ERO A;  1WL1 A;  4Q23 A;  4RXE A;  5DW7 A;  3N46 F;  2PS8 A;  5IK9 A;  5H9D A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...