5JV1F

Crystal structure of human fpps in complex with an allosteric inhibitor cl-08-066
Total Genus 125
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
sequence length
342
structure length
336
Chain Sequence
VYAQEKQDFVQHFSQIVRVLTEHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
molecule keywords Farnesyl pyrophosphate synthase
publication title Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase.
pubmed doi rcsb
source organism Homo sapiens
total genus 125
structure length 336
sequence length 342
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2016-05-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 5jv1F00
5E8HA 4KPDA 3WJKA 1V4HA 2VF6A 5E8KA 2OA6A 1JFGA 3QKCA 4DXJA 2F9KF 1UBXA 4LFGA 2RAHA 3IBAA 3PYAA 5E8LA 5ILJA 1WMWA 4XQTF 3W7FA 2Q58A 3KROA 4QXSF 4NFIF 4GP1A 5DHIA 5HN7A 4F6VA 2AZLA 5IMPA 1KIYA 2Z4XA 2ZY1A 4OGUA 3S4JA 4UMJA 5B0JA 5JA0F 3QQVA 3WEHA 5DGNF 1N24A 3ID0A 1UBVA 3M9UA 3WCLA 4LZ0A 2E8TA 3WEIA 4RXAA 2AEKA 3NPKA 5IVGA 4LUUA 4GA3A 5DJRF 4PVXF 4E9UA 2F89F 1ZW5A 3N3LF 2I19A 4KVYA 5ER8A 3OACB 1JFAA 3WCMA 5IM1A 1YHKA 4OKZA 3S9VA 3VJ9A 2E94A 1YYTA 1N23A 5KSXF 3P5RA 3CKEA 3N45F 1VG4A 3BNYA 3WEJA 4DEMF 2OPNA 3V66A 5IL3A 4DWGA 3ICKA 4NG6A 4EA0A 3KRPB 3TFPA 5HN9A 3AQBB 4FJQA 3V1XA 1YYRA 4LFEA 4QPFA 4GAXA 4PVYF 3KRAA 1HXGA 5B0KA 4KUXA 2E90A 2QISA 4NUAA 3ZMCA 3AQ0A 3SDQA 2F8ZF 4KK2A 4LFVF 5IK6A 3WE9A 3LEEA 1YQ7A 2ZEVA 5ILHA 4WK5A 1WL1A 4RXDA 2Z78A 4P0WA 3WCAA 1RTRA 1WL3A 5B01A 1RQIA 2P1CA 3LMDA 3WCFA 3KROB 3CP6A 4OMHA 2E93A 4JYXA 3SDRA 3NF2A 4KPJA 2AETA 4H5DF 5H9DA 4DI5A 4EA2A 2E8VA 2Z52A 4MC3A 3SAEA 4KWDA 3VJ8A 2Q9ZA 3N49F 1WL0A 4LTVA 3N0FA 1V4IA 3WCGA 3TFVA 3BNXA 1WY0A 3V1VA 3ZL6A 3WEKA 4DHDA 2DH4A 4LLTA 5ERMA 3ACWA 3LG5A 2ZCSA 2H8OA 4LZ3A 5ILKA 1UBWA 3SDVA 1UBYA 2J1OA 3WEFA 3OABA 2Z4YA 4H5CF 2Z50A 3WCJA 5IL8A 1N20A 3IPIA 3KRCA 3EGTA 4LPHF 2ZCOA 3M00A 3WJNA 1YHLA 3WSBA 5ILIA 1V4EA 5A0IA 3LK5A 1VG2A 3RBMA 3MAVA 3LJIA 2F7MF 5IN8A 3WCEA 5IMIA 1N1ZA 3ASXA 3KB9A 4LTZA 3KRAB 4E1EA 3ZCDA 1V4KA 3VJEA 3WCHA 5AELA 3KRFB 4RYPA 3P41A 5JV2F 4KVWA 4LA6A 5B0MA 3ICZA 4P0XA 3N1VF 5C05A 3ACYA 2O1OA 4RNQA 3KBKA 2J1PA 3DYFA 5DHKA 3WJOA 4NFKF 4K10A 3ICNA 5EROA 5HNAA 4NKFA 2ONHA 3LGKA 1WL2A 4GP2A 3B7LA 3G4DA 3APZA 3N5JF 4KQUA 4RXCA 1DGPA 3NPRA 4L2XF 5JUZF 2E95A 4NFJF 2ZCRA 3LGZB 4KKMA 2Z4WA 3LVSA 3WCDA 4ZQ8A 2PS4A 4OKMA 1YYSA 4Q23A 3N5HF 3DYGA 5CG6A 3P8RA 5EATA 5I1UA 5DJPF 2F92F 3ZMBA 3Q2ZA 4JZXA 4XQRF 3KRPA 3PKOA 2E8UA 3TFNA 1VG6A 5DIQF 3OABB 3CC9A 2Z4ZA 5EAUA 3N6KF 2E91A 3UCAA 5EASA 3TS7A 4F62A 1VG7A 3WEGA 5DGSF 1HM7A 5ILDA 5DJVF 1V4JA 3N46F 3ZOUA 5HN8A 4MC0A 4JZBA 3LZ9A 3LLWA 4F6XA 1VG3A 3P5PA 1YJ4A 4LA5A 4KFAA 4KVDA 4DZWA 3OYRA 3PH7A 5ILZA 4KQSA 5ERNA 5B03A 3WCBA 3WCIA 1YHMA 4LZCA 1HXAA 5IKHA 3G4FA 3M01A 2E4OA 3EFQA 2PS5A 3ADZA 3M0GA 3M02A 2AZJA 4FP4A 4KQ5A 3Q30A 5CG5A 3Q1OA 5ILYA 5DZ2A 3RYEA 4LIXA 1YV5A 3WC9A 3Q2QA 3VJAA 1N22A 5JV0F 1KIZA 3LSNA 3PDEA 1DI1A 4LPGF 3RYWA 1EZFA 2OGDA 3RMGA 5IMNA 3ACXA 5B0IA 2E8WA 3MZVA 4JXNA 3EZ3A 5AHUB 2Z7IA 4XQSF 1HXCA 2EWGA 3SDTA 1YYUA 2PS8A 4DWBA 3LDWA 3VJBA 4H5EF 1FPSA 4EA1A 3P8LA 2Q80A 5DGMF 2OPMA 2E8XA 4RXEA 1PS1A 4LXWA 5JV1F 4OMGA 1HM4A 2F94F 2Z7HA 3WSAA 3VJCA 5AFXA 3N3DA 5B02A 5IKAA 3NRIA 2FTZA 3VJDA 2F8CF 4NKEA 2Q9YA 3OACA 4MC8A 5B00A 3N1WF 3SDUA 5IK9A 3DYHA 2PS6A 4KVIA 4JVJF 3KRFA 5IK0A 3LOMA 4N1ZF 4N9UA 3PYBA 2FORA 5DW7A 2AELA 4E9ZA 1RQJA 4LOBA 2AZKA 1WKZA 2E92A 3AQCB 2J5CA 2ZCQA 1HX9A 2PS7A 1N1BA 3WCCA 3AE0A 5A0JA 4LLSA 5AYPA 2ZEUA 4P0VA 5B0LA 2ONGA 3KRCB 2Z4VA 3TC1A 5A0KA 4JXYA 1N21A 1YYQA 3N0GA 3ICMA 4HD1A
chains in the Genus database with same CATH superfamily
5E8HA 4KPDA 3WJKA 1V4HA 2VF6A 5E8KA 2OA6A 1JFGA 3QKCA 4DXJA 2F9KF 1UBXA 4LFGA 2RAHA 3IBAA 3PYAA 5E8LA 5ILJA 1WMWA 4XQTF 3W7FA 2Q58A 3KROA 4QXSF 4NFIF 4GP1A 5DHIA 5HN7A 4F6VA 2AZLA 5IMPA 1KIYA 2Z4XA 2ZY1A 4OGUA 3S4JA 4UMJA 5B0JA 5JA0F 3QQVA 3WEHA 5DGNF 1N24A 3ID0A 1UBVA 3M9UA 3WCLA 4LZ0A 2E8TA 3WEIA 4RXAA 2AEKA 3NPKA 5IVGA 4LUUA 4GA3A 5DJRF 4PVXF 4E9UA 2F89F 1ZW5A 3N3LF 2I19A 4KVYA 5ER8A 3OACB 1JFAA 3WCMA 5IM1A 1YHKA 4OKZA 3S9VA 3VJ9A 2E94A 1YYTA 1N23A 5KSXF 3P5RA 3CKEA 3N45F 1VG4A 3BNYA 3WEJA 4DEMF 2OPNA 3V66A 5IL3A 4DWGA 3ICKA 4NG6A 4EA0A 3KRPB 3TFPA 5HN9A 3AQBB 4FJQA 3V1XA 1YYRA 4LFEA 4QPFA 4GAXA 4PVYF 3KRAA 1HXGA 5B0KA 4KUXA 2E90A 2QISA 4NUAA 3ZMCA 3AQ0A 3SDQA 2F8ZF 4KK2A 4LFVF 5IK6A 3WE9A 3LEEA 1YQ7A 2ZEVA 5ILHA 4WK5A 1WL1A 4RXDA 2Z78A 4P0WA 3WCAA 1RTRA 1WL3A 5B01A 1RQIA 2P1CA 3LMDA 3WCFA 3KROB 3CP6A 4OMHA 2E93A 4JYXA 3SDRA 3NF2A 4KPJA 2AETA 4H5DF 5H9DA 4DI5A 4EA2A 2E8VA 2Z52A 4MC3A 3SAEA 4KWDA 3VJ8A 2Q9ZA 3N49F 1WL0A 4LTVA 3N0FA 1V4IA 3WCGA 3TFVA 3BNXA 1WY0A 3V1VA 3ZL6A 3WEKA 4DHDA 2DH4A 4LLTA 5ERMA 3ACWA 3LG5A 2ZCSA 2H8OA 4LZ3A 5ILKA 1UBWA 3SDVA 1UBYA 2J1OA 3WEFA 3OABA 2Z4YA 4H5CF 2Z50A 3WCJA 5IL8A 1N20A 3IPIA 3KRCA 3EGTA 4LPHF 2ZCOA 3M00A 3WJNA 1YHLA 3WSBA 5ILIA 1V4EA 5A0IA 3LK5A 1VG2A 3RBMA 3MAVA 3LJIA 2F7MF 5IN8A 3WCEA 5IMIA 1N1ZA 3ASXA 3KB9A 4LTZA 3KRAB 4E1EA 3ZCDA 1V4KA 3VJEA 3WCHA 5AELA 3KRFB 4RYPA 3P41A 5JV2F 4KVWA 4LA6A 5B0MA 3ICZA 4P0XA 3N1VF 5C05A 3ACYA 2O1OA 4RNQA 3KBKA 2J1PA 3DYFA 5DHKA 3WJOA 4NFKF 4K10A 3ICNA 5EROA 5HNAA 4NKFA 2ONHA 3LGKA 1WL2A 4GP2A 3B7LA 3G4DA 3APZA 3N5JF 4KQUA 4RXCA 1DGPA 3NPRA 4L2XF 5JUZF 2E95A 4NFJF 2ZCRA 3LGZB 4KKMA 2Z4WA 3LVSA 3WCDA 4ZQ8A 2PS4A 4OKMA 1YYSA 4Q23A 3N5HF 3DYGA 5CG6A 3P8RA 5EATA 5I1UA 5DJPF 2F92F 3ZMBA 3Q2ZA 4JZXA 4XQRF 3KRPA 3PKOA 2E8UA 3TFNA 1VG6A 5DIQF 3OABB 3CC9A 2Z4ZA 5EAUA 3N6KF 2E91A 3UCAA 5EASA 3TS7A 4F62A 1VG7A 3WEGA 5DGSF 1HM7A 5ILDA 5DJVF 1V4JA 3N46F 3ZOUA 5HN8A 4MC0A 4JZBA 3LZ9A 3LLWA 4F6XA 1VG3A 3P5PA 1YJ4A 4LA5A 4KFAA 4KVDA 4DZWA 3OYRA 3PH7A 5ILZA 4KQSA 5ERNA 5B03A 3WCBA 3WCIA 1YHMA 4LZCA 1HXAA 5IKHA 3G4FA 3M01A 2E4OA 3EFQA 2PS5A 3ADZA 3M0GA 3M02A 2AZJA 4FP4A 4KQ5A 3Q30A 5CG5A 3Q1OA 5ILYA 5DZ2A 3RYEA 4LIXA 1YV5A 3WC9A 3Q2QA 3VJAA 1N22A 5JV0F 1KIZA 3LSNA 3PDEA 1DI1A 4LPGF 3RYWA 1EZFA 2OGDA 3RMGA 5IMNA 3ACXA 5B0IA 2E8WA 3MZVA 4JXNA 3EZ3A 5AHUB 2Z7IA 4XQSF 1HXCA 2EWGA 3SDTA 1YYUA 2PS8A 4DWBA 3LDWA 3VJBA 4H5EF 1FPSA 4EA1A 3P8LA 2Q80A 5DGMF 2OPMA 2E8XA 4RXEA 1PS1A 4LXWA 5JV1F 4OMGA 1HM4A 2F94F 2Z7HA 3WSAA 3VJCA 5AFXA 3N3DA 5B02A 5IKAA 3NRIA 2FTZA 3VJDA 2F8CF 4NKEA 2Q9YA 3OACA 4MC8A 5B00A 3N1WF 3SDUA 5IK9A 3DYHA 2PS6A 4KVIA 4JVJF 3KRFA 5IK0A 3LOMA 4N1ZF 4N9UA 3PYBA 2FORA 5DW7A 2AELA 4E9ZA 1RQJA 4LOBA 2AZKA 1WKZA 2E92A 3AQCB 2J5CA 2ZCQA 1HX9A 2PS7A 1N1BA 3WCCA 3AE0A 5A0JA 4LLSA 5AYPA 2ZEUA 4P0VA 5B0LA 2ONGA 3KRCB 2Z4VA 3TC1A 5A0KA 4JXYA 1N21A 1YYQA 3N0GA 3ICMA 4HD1A
chains in the Genus database with same CATH topology
5E8HA 4KPDA 3WJKA 1V4HA 2VF6A 5E8KA 2OA6A 1JFGA 3QKCA 4DXJA 2F9KF 1UBXA 4LFGA 2RAHA 3IBAA 3PYAA 5E8LA 5ILJA 1WMWA 4XQTF 3W7FA 2Q58A 3KROA 4QXSF 4NFIF 4GP1A 5DHIA 5HN7A 4F6VA 2AZLA 5IMPA 1KIYA 2Z4XA 2ZY1A 4OGUA 3S4JA 4UMJA 5B0JA 5JA0F 3QQVA 3WEHA 5DGNF 1N24A 3ID0A 1UBVA 3M9UA 3WCLA 4LZ0A 2E8TA 3WEIA 4RXAA 2AEKA 3NPKA 5IVGA 4LUUA 4GA3A 5DJRF 4PVXF 4E9UA 2F89F 1ZW5A 3N3LF 2I19A 4KVYA 5ER8A 3OACB 1JFAA 3WCMA 5IM1A 1YHKA 4OKZA 3S9VA 3VJ9A 2E94A 1YYTA 1N23A 5KSXF 3P5RA 3CKEA 3N45F 1VG4A 3BNYA 3WEJA 4DEMF 2OPNA 3V66A 5IL3A 4DWGA 3ICKA 4NG6A 4EA0A 3KRPB 3TFPA 5HN9A 3AQBB 4FJQA 3V1XA 1YYRA 4LFEA 4QPFA 4GAXA 4PVYF 3KRAA 1HXGA 5B0KA 4KUXA 2E90A 2QISA 4NUAA 3ZMCA 3AQ0A 3SDQA 2F8ZF 4KK2A 4LFVF 5IK6A 3WE9A 3LEEA 1YQ7A 2ZEVA 5ILHA 4WK5A 1WL1A 4RXDA 2Z78A 4P0WA 3WCAA 1RTRA 1WL3A 5B01A 1RQIA 2P1CA 3LMDA 3WCFA 3KROB 3CP6A 4OMHA 2E93A 4JYXA 3SDRA 3NF2A 4KPJA 2AETA 4H5DF 5H9DA 4DI5A 4EA2A 2E8VA 2Z52A 4MC3A 3SAEA 4KWDA 3VJ8A 2Q9ZA 3N49F 1WL0A 4LTVA 3N0FA 1V4IA 3WCGA 3TFVA 3BNXA 1WY0A 3V1VA 3ZL6A 3WEKA 4DHDA 2DH4A 4LLTA 5ERMA 3ACWA 3LG5A 2ZCSA 2H8OA 4LZ3A 5ILKA 1UBWA 3SDVA 1UBYA 2J1OA 3WEFA 3OABA 2Z4YA 4H5CF 2Z50A 3WCJA 5IL8A 1N20A 3IPIA 3KRCA 3EGTA 4LPHF 2ZCOA 3M00A 3WJNA 1YHLA 3WSBA 5ILIA 1V4EA 5A0IA 3LK5A 1VG2A 3RBMA 3MAVA 3LJIA 2F7MF 5IN8A 3WCEA 5IMIA 1N1ZA 3ASXA 3KB9A 4LTZA 3KRAB 4E1EA 3ZCDA 1V4KA 3VJEA 3WCHA 5AELA 3KRFB 4RYPA 3P41A 5JV2F 4KVWA 4LA6A 5B0MA 3ICZA 4P0XA 3N1VF 5C05A 3ACYA 2O1OA 4RNQA 3KBKA 2J1PA 3DYFA 5DHKA 3WJOA 4NFKF 4K10A 3ICNA 5EROA 5HNAA 4NKFA 2ONHA 3LGKA 1WL2A 4GP2A 3B7LA 3G4DA 3APZA 3N5JF 4KQUA 4RXCA 1DGPA 3NPRA 4L2XF 5JUZF 2E95A 4NFJF 2ZCRA 3LGZB 4KKMA 2Z4WA 3LVSA 3WCDA 4ZQ8A 2PS4A 4OKMA 1YYSA 4Q23A 3N5HF 3DYGA 5CG6A 3P8RA 5EATA 5I1UA 5DJPF 2F92F 3ZMBA 3Q2ZA 4JZXA 4XQRF 3KRPA 3PKOA 2E8UA 3TFNA 1VG6A 5DIQF 3OABB 3CC9A 2Z4ZA 5EAUA 3N6KF 2E91A 3UCAA 5EASA 3TS7A 4F62A 1VG7A 3WEGA 5DGSF 1HM7A 5ILDA 5DJVF 1V4JA 3N46F 3ZOUA 5HN8A 4MC0A 4JZBA 3LZ9A 3LLWA 4F6XA 1VG3A 3P5PA 1YJ4A 4LA5A 4KFAA 4KVDA 4DZWA 3OYRA 3PH7A 5ILZA 4KQSA 5ERNA 5B03A 3WCBA 3WCIA 1YHMA 4LZCA 1HXAA 5IKHA 3G4FA 3M01A 2E4OA 3EFQA 2PS5A 3ADZA 3M0GA 3M02A 2AZJA 4FP4A 4KQ5A 3Q30A 5CG5A 3Q1OA 5ILYA 5DZ2A 3RYEA 4LIXA 1YV5A 3WC9A 3Q2QA 3VJAA 1N22A 5JV0F 1KIZA 3LSNA 3PDEA 1DI1A 4LPGF 3RYWA 1EZFA 2OGDA 3RMGA 5IMNA 3ACXA 5B0IA 2E8WA 3MZVA 4JXNA 3EZ3A 5AHUB 2Z7IA 4XQSF 1HXCA 2EWGA 3SDTA 1YYUA 2PS8A 4DWBA 3LDWA 3VJBA 4H5EF 1FPSA 4EA1A 3P8LA 2Q80A 5DGMF 2OPMA 2E8XA 4RXEA 1PS1A 4LXWA 5JV1F 4OMGA 1HM4A 2F94F 2Z7HA 3WSAA 3VJCA 5AFXA 3N3DA 5B02A 5IKAA 3NRIA 2FTZA 3VJDA 2F8CF 4NKEA 2Q9YA 3OACA 4MC8A 5B00A 3N1WF 3SDUA 5IK9A 3DYHA 2PS6A 4KVIA 4JVJF 3KRFA 5IK0A 3LOMA 4N1ZF 4N9UA 3PYBA 2FORA 5DW7A 2AELA 4E9ZA 1RQJA 4LOBA 2AZKA 1WKZA 2E92A 3AQCB 2J5CA 2ZCQA 1HX9A 2PS7A 1N1BA 3WCCA 3AE0A 5A0JA 4LLSA 5AYPA 2ZEUA 4P0VA 5B0LA 2ONGA 3KRCB 2Z4VA 3TC1A 5A0KA 4JXYA 1N21A 1YYQA 3N0GA 3ICMA 4HD1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5E8H A;  4KPD A;  3WJK A;  1V4H A;  2VF6 A;  5E8K A;  2OA6 A;  1JFG A;  3QKC A;  4DXJ A;  2F9K F;  1UBX A;  4LFG A;  2RAH A;  3IBA A;  3PYA A;  5E8L A;  5ILJ A;  1WMW A;  4XQT F;  3W7F A;  2Q58 A;  3KRO A;  4QXS F;  4NFI F;  4GP1 A;  5DHI A;  5HN7 A;  4F6V A;  2AZL A;  5IMP A;  1KIY A;  2Z4X A;  2ZY1 A;  4OGU A;  3S4J A;  4UMJ A;  5B0J A;  5JA0 F;  3QQV A;  3WEH A;  5DGN F;  1N24 A;  3ID0 A;  1UBV A;  3M9U A;  3WCL A;  4LZ0 A;  2E8T A;  3WEI A;  4RXA A;  2AEK A;  3NPK A;  5IVG A;  4LUU A;  4GA3 A;  5DJR F;  4PVX F;  4E9U A;  2F89 F;  1ZW5 A;  3N3L F;  2I19 A;  4KVY A;  5ER8 A;  3OAC B;  1JFA A;  3WCM A;  5IM1 A;  1YHK A;  4OKZ A;  3S9V A;  3VJ9 A;  2E94 A;  1YYT A;  1N23 A;  5KSX F;  3P5R A;  3CKE A;  3N45 F;  1VG4 A;  3BNY A;  3WEJ A;  4DEM F;  2OPN A;  3V66 A;  5IL3 A;  4DWG A;  3ICK A;  4NG6 A;  4EA0 A;  3KRP B;  3TFP A;  5HN9 A;  3AQB B;  4FJQ A;  3V1X A;  1YYR A;  4LFE A;  4QPF A;  4GAX A;  4PVY F;  3KRA A;  1HXG A;  5B0K A;  4KUX A;  2E90 A;  2QIS A;  4NUA A;  3ZMC A;  3AQ0 A;  3SDQ A;  2F8Z F;  4KK2 A;  4LFV F;  5IK6 A;  3WE9 A;  3LEE A;  1YQ7 A;  2ZEV A;  5ILH A;  4WK5 A;  1WL1 A;  4RXD A;  2Z78 A;  4P0W A;  3WCA A;  1RTR A;  1WL3 A;  5B01 A;  1RQI A;  2P1C A;  3LMD A;  3WCF A;  3KRO B;  3CP6 A;  4OMH A;  2E93 A;  4JYX A;  3SDR A;  3NF2 A;  4KPJ A;  2AET A;  4H5D F;  5H9D A;  4DI5 A;  4EA2 A;  2E8V A;  2Z52 A;  4MC3 A;  3SAE A;  4KWD A;  3VJ8 A;  2Q9Z A;  3N49 F;  1WL0 A;  4LTV A;  3N0F A;  1V4I A;  3WCG A;  3TFV A;  3BNX A;  1WY0 A;  3V1V A;  3ZL6 A;  3WEK A;  4DHD A;  2DH4 A;  4LLT A;  5ERM A;  3ACW A;  3LG5 A;  2ZCS A;  2H8O A;  4LZ3 A;  5ILK A;  1UBW A;  3SDV A;  1UBY A;  2J1O A;  3WEF A;  3OAB A;  2Z4Y A;  4H5C F;  2Z50 A;  3WCJ A;  5IL8 A;  1N20 A;  3IPI A;  3KRC A;  3EGT A;  4LPH F;  2ZCO A;  3M00 A;  3WJN A;  1YHL A;  3WSB A;  5ILI A;  1V4E A;  5A0I A;  3LK5 A;  1VG2 A;  3RBM A;  3MAV A;  3LJI A;  2F7M F;  5IN8 A;  3WCE A;  5IMI A;  1N1Z A;  3ASX A;  3KB9 A;  4LTZ A;  3KRA B;  4E1E A;  3ZCD A;  1V4K A;  3VJE A;  3WCH A;  5AEL A;  3KRF B;  4RYP A;  3P41 A;  5JV2 F;  4KVW A;  4LA6 A;  5B0M A;  3ICZ A;  4P0X A;  3N1V F;  5C05 A;  3ACY A;  2O1O A;  4RNQ A;  3KBK A;  2J1P A;  3DYF A;  5DHK A;  3WJO A;  4NFK F;  4K10 A;  3ICN A;  5ERO A;  5HNA A;  4NKF A;  2ONH A;  3LGK A;  1WL2 A;  4GP2 A;  3B7L A;  3G4D A;  3APZ A;  3N5J F;  4KQU A;  4RXC A;  1DGP A;  3NPR A;  4L2X F;  5JUZ F;  2E95 A;  4NFJ F;  2ZCR A;  3LGZ B;  4KKM A;  2Z4W A;  3LVS A;  3WCD A;  4ZQ8 A;  2PS4 A;  4OKM A;  1YYS A;  4Q23 A;  3N5H F;  3DYG A;  5CG6 A;  3P8R A;  5EAT A;  5I1U A;  5DJP F;  2F92 F;  3ZMB A;  3Q2Z A;  4JZX A;  4XQR F;  3KRP A;  3PKO A;  2E8U A;  3TFN A;  1VG6 A;  5DIQ F;  3OAB B;  3CC9 A;  2Z4Z A;  5EAU A;  3N6K F;  2E91 A;  3UCA A;  5EAS A;  3TS7 A;  4F62 A;  1VG7 A;  3WEG A;  5DGS F;  1HM7 A;  5ILD A;  5DJV F;  1V4J A;  3N46 F;  3ZOU A;  5HN8 A;  4MC0 A;  4JZB A;  3LZ9 A;  3LLW A;  4F6X A;  1VG3 A;  3P5P A;  1YJ4 A;  4LA5 A;  4KFA A;  4KVD A;  4DZW A;  3OYR A;  3PH7 A;  5ILZ A;  4KQS A;  5ERN A;  5B03 A;  3WCB A;  3WCI A;  1YHM A;  4LZC A;  1HXA A;  5IKH A;  3G4F A;  3M01 A;  2E4O A;  3EFQ A;  2PS5 A;  3ADZ A;  3M0G A;  3M02 A;  2AZJ A;  4FP4 A;  4KQ5 A;  3Q30 A;  5CG5 A;  3Q1O A;  5ILY A;  5DZ2 A;  3RYE A;  4LIX A;  1YV5 A;  3WC9 A;  3Q2Q A;  3VJA A;  1N22 A;  5JV0 F;  1KIZ A;  3LSN A;  3PDE A;  1DI1 A;  4LPG F;  3RYW A;  1EZF A;  2OGD A;  3RMG A;  5IMN A;  3ACX A;  5B0I A;  2E8W A;  3MZV A;  4JXN A;  3EZ3 A;  5AHU B;  2Z7I A;  4XQS F;  1HXC A;  2EWG A;  3SDT A;  1YYU A;  2PS8 A;  4DWB A;  3LDW A;  3VJB A;  4H5E F;  1FPS A;  4EA1 A;  3P8L A;  2Q80 A;  5DGM F;  2OPM A;  2E8X A;  4RXE A;  1PS1 A;  4LXW A;  5JV1 F;  4OMG A;  1HM4 A;  2F94 F;  2Z7H A;  3WSA A;  3VJC A;  5AFX A;  3N3D A;  5B02 A;  5IKA A;  3NRI A;  2FTZ A;  3VJD A;  2F8C F;  4NKE A;  2Q9Y A;  3OAC A;  4MC8 A;  5B00 A;  3N1W F;  3SDU A;  5IK9 A;  3DYH A;  2PS6 A;  4KVI A;  4JVJ F;  3KRF A;  5IK0 A;  3LOM A;  4N1Z F;  4N9U A;  3PYB A;  2FOR A;  5DW7 A;  2AEL A;  4E9Z A;  1RQJ A;  4LOB A;  2AZK A;  1WKZ A;  2E92 A;  3AQC B;  2J5C A;  2ZCQ A;  1HX9 A;  2PS7 A;  1N1B A;  3WCC A;  3AE0 A;  5A0J A;  4LLS A;  5AYP A;  2ZEU A;  4P0V A;  5B0L A;  2ONG A;  3KRC B;  2Z4V A;  3TC1 A;  5A0K A;  4JXY A;  1N21 A;  1YYQ A;  3N0G A;  3ICM A;  4HD1 A; 
#chains in the Genus database with same CATH topology
 5E8H A;  4KPD A;  3WJK A;  1V4H A;  2VF6 A;  5E8K A;  2OA6 A;  1JFG A;  3QKC A;  4DXJ A;  2F9K F;  1UBX A;  4LFG A;  2RAH A;  3IBA A;  3PYA A;  5E8L A;  5ILJ A;  1WMW A;  4XQT F;  3W7F A;  2Q58 A;  3KRO A;  4QXS F;  4NFI F;  4GP1 A;  5DHI A;  5HN7 A;  4F6V A;  2AZL A;  5IMP A;  1KIY A;  2Z4X A;  2ZY1 A;  4OGU A;  3S4J A;  4UMJ A;  5B0J A;  5JA0 F;  3QQV A;  3WEH A;  5DGN F;  1N24 A;  3ID0 A;  1UBV A;  3M9U A;  3WCL A;  4LZ0 A;  2E8T A;  3WEI A;  4RXA A;  2AEK A;  3NPK A;  5IVG A;  4LUU A;  4GA3 A;  5DJR F;  4PVX F;  4E9U A;  2F89 F;  1ZW5 A;  3N3L F;  2I19 A;  4KVY A;  5ER8 A;  3OAC B;  1JFA A;  3WCM A;  5IM1 A;  1YHK A;  4OKZ A;  3S9V A;  3VJ9 A;  2E94 A;  1YYT A;  1N23 A;  5KSX F;  3P5R A;  3CKE A;  3N45 F;  1VG4 A;  3BNY A;  3WEJ A;  4DEM F;  2OPN A;  3V66 A;  5IL3 A;  4DWG A;  3ICK A;  4NG6 A;  4EA0 A;  3KRP B;  3TFP A;  5HN9 A;  3AQB B;  4FJQ A;  3V1X A;  1YYR A;  4LFE A;  4QPF A;  4GAX A;  4PVY F;  3KRA A;  1HXG A;  5B0K A;  4KUX A;  2E90 A;  2QIS A;  4NUA A;  3ZMC A;  3AQ0 A;  3SDQ A;  2F8Z F;  4KK2 A;  4LFV F;  5IK6 A;  3WE9 A;  3LEE A;  1YQ7 A;  2ZEV A;  5ILH A;  4WK5 A;  1WL1 A;  4RXD A;  2Z78 A;  4P0W A;  3WCA A;  1RTR A;  1WL3 A;  5B01 A;  1RQI A;  2P1C A;  3LMD A;  3WCF A;  3KRO B;  3CP6 A;  4OMH A;  2E93 A;  4JYX A;  3SDR A;  3NF2 A;  4KPJ A;  2AET A;  4H5D F;  5H9D A;  4DI5 A;  4EA2 A;  2E8V A;  2Z52 A;  4MC3 A;  3SAE A;  4KWD A;  3VJ8 A;  2Q9Z A;  3N49 F;  1WL0 A;  4LTV A;  3N0F A;  1V4I A;  3WCG A;  3TFV A;  3BNX A;  1WY0 A;  3V1V A;  3ZL6 A;  3WEK A;  4DHD A;  2DH4 A;  4LLT A;  5ERM A;  3ACW A;  3LG5 A;  2ZCS A;  2H8O A;  4LZ3 A;  5ILK A;  1UBW A;  3SDV A;  1UBY A;  2J1O A;  3WEF A;  3OAB A;  2Z4Y A;  4H5C F;  2Z50 A;  3WCJ A;  5IL8 A;  1N20 A;  3IPI A;  3KRC A;  3EGT A;  4LPH F;  2ZCO A;  3M00 A;  3WJN A;  1YHL A;  3WSB A;  5ILI A;  1V4E A;  5A0I A;  3LK5 A;  1VG2 A;  3RBM A;  3MAV A;  3LJI A;  2F7M F;  5IN8 A;  3WCE A;  5IMI A;  1N1Z A;  3ASX A;  3KB9 A;  4LTZ A;  3KRA B;  4E1E A;  3ZCD A;  1V4K A;  3VJE A;  3WCH A;  5AEL A;  3KRF B;  4RYP A;  3P41 A;  5JV2 F;  4KVW A;  4LA6 A;  5B0M A;  3ICZ A;  4P0X A;  3N1V F;  5C05 A;  3ACY A;  2O1O A;  4RNQ A;  3KBK A;  2J1P A;  3DYF A;  5DHK A;  3WJO A;  4NFK F;  4K10 A;  3ICN A;  5ERO A;  5HNA A;  4NKF A;  2ONH A;  3LGK A;  1WL2 A;  4GP2 A;  3B7L A;  3G4D A;  3APZ A;  3N5J F;  4KQU A;  4RXC A;  1DGP A;  3NPR A;  4L2X F;  5JUZ F;  2E95 A;  4NFJ F;  2ZCR A;  3LGZ B;  4KKM A;  2Z4W A;  3LVS A;  3WCD A;  4ZQ8 A;  2PS4 A;  4OKM A;  1YYS A;  4Q23 A;  3N5H F;  3DYG A;  5CG6 A;  3P8R A;  5EAT A;  5I1U A;  5DJP F;  2F92 F;  3ZMB A;  3Q2Z A;  4JZX A;  4XQR F;  3KRP A;  3PKO A;  2E8U A;  3TFN A;  1VG6 A;  5DIQ F;  3OAB B;  3CC9 A;  2Z4Z A;  5EAU A;  3N6K F;  2E91 A;  3UCA A;  5EAS A;  3TS7 A;  4F62 A;  1VG7 A;  3WEG A;  5DGS F;  1HM7 A;  5ILD A;  5DJV F;  1V4J A;  3N46 F;  3ZOU A;  5HN8 A;  4MC0 A;  4JZB A;  3LZ9 A;  3LLW A;  4F6X A;  1VG3 A;  3P5P A;  1YJ4 A;  4LA5 A;  4KFA A;  4KVD A;  4DZW A;  3OYR A;  3PH7 A;  5ILZ A;  4KQS A;  5ERN A;  5B03 A;  3WCB A;  3WCI A;  1YHM A;  4LZC A;  1HXA A;  5IKH A;  3G4F A;  3M01 A;  2E4O A;  3EFQ A;  2PS5 A;  3ADZ A;  3M0G A;  3M02 A;  2AZJ A;  4FP4 A;  4KQ5 A;  3Q30 A;  5CG5 A;  3Q1O A;  5ILY A;  5DZ2 A;  3RYE A;  4LIX A;  1YV5 A;  3WC9 A;  3Q2Q A;  3VJA A;  1N22 A;  5JV0 F;  1KIZ A;  3LSN A;  3PDE A;  1DI1 A;  4LPG F;  3RYW A;  1EZF A;  2OGD A;  3RMG A;  5IMN A;  3ACX A;  5B0I A;  2E8W A;  3MZV A;  4JXN A;  3EZ3 A;  5AHU B;  2Z7I A;  4XQS F;  1HXC A;  2EWG A;  3SDT A;  1YYU A;  2PS8 A;  4DWB A;  3LDW A;  3VJB A;  4H5E F;  1FPS A;  4EA1 A;  3P8L A;  2Q80 A;  5DGM F;  2OPM A;  2E8X A;  4RXE A;  1PS1 A;  4LXW A;  5JV1 F;  4OMG A;  1HM4 A;  2F94 F;  2Z7H A;  3WSA A;  3VJC A;  5AFX A;  3N3D A;  5B02 A;  5IKA A;  3NRI A;  2FTZ A;  3VJD A;  2F8C F;  4NKE A;  2Q9Y A;  3OAC A;  4MC8 A;  5B00 A;  3N1W F;  3SDU A;  5IK9 A;  3DYH A;  2PS6 A;  4KVI A;  4JVJ F;  3KRF A;  5IK0 A;  3LOM A;  4N1Z F;  4N9U A;  3PYB A;  2FOR A;  5DW7 A;  2AEL A;  4E9Z A;  1RQJ A;  4LOB A;  2AZK A;  1WKZ A;  2E92 A;  3AQC B;  2J5C A;  2ZCQ A;  1HX9 A;  2PS7 A;  1N1B A;  3WCC A;  3AE0 A;  5A0J A;  4LLS A;  5AYP A;  2ZEU A;  4P0V A;  5B0L A;  2ONG A;  3KRC B;  2Z4V A;  3TC1 A;  5A0K A;  4JXY A;  1N21 A;  1YYQ A;  3N0G A;  3ICM A;  4HD1 A; 
#chains in the Genus database with same CATH homology
 5E8H A;  4KPD A;  3WJK A;  1V4H A;  2VF6 A;  5E8K A;  2OA6 A;  1JFG A;  3QKC A;  4DXJ A;  2F9K F;  1UBX A;  4LFG A;  2RAH A;  3IBA A;  3PYA A;  5E8L A;  5ILJ A;  1WMW A;  4XQT F;  3W7F A;  2Q58 A;  3KRO A;  4QXS F;  4NFI F;  4GP1 A;  5DHI A;  5HN7 A;  4F6V A;  2AZL A;  5IMP A;  1KIY A;  2Z4X A;  2ZY1 A;  4OGU A;  3S4J A;  4UMJ A;  5B0J A;  5JA0 F;  3QQV A;  3WEH A;  5DGN F;  1N24 A;  3ID0 A;  1UBV A;  3M9U A;  3WCL A;  4LZ0 A;  2E8T A;  3WEI A;  4RXA A;  2AEK A;  3NPK A;  5IVG A;  4LUU A;  4GA3 A;  5DJR F;  4PVX F;  4E9U A;  2F89 F;  1ZW5 A;  3N3L F;  2I19 A;  4KVY A;  5ER8 A;  3OAC B;  1JFA A;  3WCM A;  5IM1 A;  1YHK A;  4OKZ A;  3S9V A;  3VJ9 A;  2E94 A;  1YYT A;  1N23 A;  5KSX F;  3P5R A;  3CKE A;  3N45 F;  1VG4 A;  3BNY A;  3WEJ A;  4DEM F;  2OPN A;  3V66 A;  5IL3 A;  4DWG A;  3ICK A;  4NG6 A;  4EA0 A;  3KRP B;  3TFP A;  5HN9 A;  3AQB B;  4FJQ A;  3V1X A;  1YYR A;  4LFE A;  4QPF A;  4GAX A;  4PVY F;  3KRA A;  1HXG A;  5B0K A;  4KUX A;  2E90 A;  2QIS A;  4NUA A;  3ZMC A;  3AQ0 A;  3SDQ A;  2F8Z F;  4KK2 A;  4LFV F;  5IK6 A;  3WE9 A;  3LEE A;  1YQ7 A;  2ZEV A;  5ILH A;  4WK5 A;  1WL1 A;  4RXD A;  2Z78 A;  4P0W A;  3WCA A;  1RTR A;  1WL3 A;  5B01 A;  1RQI A;  2P1C A;  3LMD A;  3WCF A;  3KRO B;  3CP6 A;  4OMH A;  2E93 A;  4JYX A;  3SDR A;  3NF2 A;  4KPJ A;  2AET A;  4H5D F;  5H9D A;  4DI5 A;  4EA2 A;  2E8V A;  2Z52 A;  4MC3 A;  3SAE A;  4KWD A;  3VJ8 A;  2Q9Z A;  3N49 F;  1WL0 A;  4LTV A;  3N0F A;  1V4I A;  3WCG A;  3TFV A;  3BNX A;  1WY0 A;  3V1V A;  3ZL6 A;  3WEK A;  4DHD A;  2DH4 A;  4LLT A;  5ERM A;  3ACW A;  3LG5 A;  2ZCS A;  2H8O A;  4LZ3 A;  5ILK A;  1UBW A;  3SDV A;  1UBY A;  2J1O A;  3WEF A;  3OAB A;  2Z4Y A;  4H5C F;  2Z50 A;  3WCJ A;  5IL8 A;  1N20 A;  3IPI A;  3KRC A;  3EGT A;  4LPH F;  2ZCO A;  3M00 A;  3WJN A;  1YHL A;  3WSB A;  5ILI A;  1V4E A;  5A0I A;  3LK5 A;  1VG2 A;  3RBM A;  3MAV A;  3LJI A;  2F7M F;  5IN8 A;  3WCE A;  5IMI A;  1N1Z A;  3ASX A;  3KB9 A;  4LTZ A;  3KRA B;  4E1E A;  3ZCD A;  1V4K A;  3VJE A;  3WCH A;  5AEL A;  3KRF B;  4RYP A;  3P41 A;  5JV2 F;  4KVW A;  4LA6 A;  5B0M A;  3ICZ A;  4P0X A;  3N1V F;  5C05 A;  3ACY A;  2O1O A;  4RNQ A;  3KBK A;  2J1P A;  3DYF A;  5DHK A;  3WJO A;  4NFK F;  4K10 A;  3ICN A;  5ERO A;  5HNA A;  4NKF A;  2ONH A;  3LGK A;  1WL2 A;  4GP2 A;  3B7L A;  3G4D A;  3APZ A;  3N5J F;  4KQU A;  4RXC A;  1DGP A;  3NPR A;  4L2X F;  5JUZ F;  2E95 A;  4NFJ F;  2ZCR A;  3LGZ B;  4KKM A;  2Z4W A;  3LVS A;  3WCD A;  4ZQ8 A;  2PS4 A;  4OKM A;  1YYS A;  4Q23 A;  3N5H F;  3DYG A;  5CG6 A;  3P8R A;  5EAT A;  5I1U A;  5DJP F;  2F92 F;  3ZMB A;  3Q2Z A;  4JZX A;  4XQR F;  3KRP A;  3PKO A;  2E8U A;  3TFN A;  1VG6 A;  5DIQ F;  3OAB B;  3CC9 A;  2Z4Z A;  5EAU A;  3N6K F;  2E91 A;  3UCA A;  5EAS A;  3TS7 A;  4F62 A;  1VG7 A;  3WEG A;  5DGS F;  1HM7 A;  5ILD A;  5DJV F;  1V4J A;  3N46 F;  3ZOU A;  5HN8 A;  4MC0 A;  4JZB A;  3LZ9 A;  3LLW A;  4F6X A;  1VG3 A;  3P5P A;  1YJ4 A;  4LA5 A;  4KFA A;  4KVD A;  4DZW A;  3OYR A;  3PH7 A;  5ILZ A;  4KQS A;  5ERN A;  5B03 A;  3WCB A;  3WCI A;  1YHM A;  4LZC A;  1HXA A;  5IKH A;  3G4F A;  3M01 A;  2E4O A;  3EFQ A;  2PS5 A;  3ADZ A;  3M0G A;  3M02 A;  2AZJ A;  4FP4 A;  4KQ5 A;  3Q30 A;  5CG5 A;  3Q1O A;  5ILY A;  5DZ2 A;  3RYE A;  4LIX A;  1YV5 A;  3WC9 A;  3Q2Q A;  3VJA A;  1N22 A;  5JV0 F;  1KIZ A;  3LSN A;  3PDE A;  1DI1 A;  4LPG F;  3RYW A;  1EZF A;  2OGD A;  3RMG A;  5IMN A;  3ACX A;  5B0I A;  2E8W A;  3MZV A;  4JXN A;  3EZ3 A;  5AHU B;  2Z7I A;  4XQS F;  1HXC A;  2EWG A;  3SDT A;  1YYU A;  2PS8 A;  4DWB A;  3LDW A;  3VJB A;  4H5E F;  1FPS A;  4EA1 A;  3P8L A;  2Q80 A;  5DGM F;  2OPM A;  2E8X A;  4RXE A;  1PS1 A;  4LXW A;  5JV1 F;  4OMG A;  1HM4 A;  2F94 F;  2Z7H A;  3WSA A;  3VJC A;  5AFX A;  3N3D A;  5B02 A;  5IKA A;  3NRI A;  2FTZ A;  3VJD A;  2F8C F;  4NKE A;  2Q9Y A;  3OAC A;  4MC8 A;  5B00 A;  3N1W F;  3SDU A;  5IK9 A;  3DYH A;  2PS6 A;  4KVI A;  4JVJ F;  3KRF A;  5IK0 A;  3LOM A;  4N1Z F;  4N9U A;  3PYB A;  2FOR A;  5DW7 A;  2AEL A;  4E9Z A;  1RQJ A;  4LOB A;  2AZK A;  1WKZ A;  2E92 A;  3AQC B;  2J5C A;  2ZCQ A;  1HX9 A;  2PS7 A;  1N1B A;  3WCC A;  3AE0 A;  5A0J A;  4LLS A;  5AYP A;  2ZEU A;  4P0V A;  5B0L A;  2ONG A;  3KRC B;  2Z4V A;  3TC1 A;  5A0K A;  4JXY A;  1N21 A;  1YYQ A;  3N0G A;  3ICM A;  4HD1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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