5DJVF

Crystal structure of human fpps in complex with biaryl compound 8e
Total Genus 125
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
sequence length
343
structure length
343
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Farnesyl pyrophosphate synthase
publication title Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 125
structure length 343
sequence length 343
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2015-09-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 5djvF00
3LVSA 3LGKA 4RYPA 5EATA 3N49F 3WEIA 3WCHA 1N1BA 5ILJA 3OACB 1N24A 3M00A 1YHKA 3LEEA 3SAEA 3WSBA 3LG5A 3EZ3A 3ZCDA 2ZEUA 5B00A 4EA2A 1YJ4A 1V4IA 2AEKA 5IL8A 2ZY1A 4E9ZA 3KRCA 3VJDA 3WJKA 4NUAA 4N9UA 5CG5A 5DJRF 3AQBB 4QPFA 4NFJF 2FTZA 5A0JA 1N20A 1N21A 1UBXA 3WEKA 1V4JA 1UBWA 3MAVA 4DWBA 3N5JF 4H5CF 4KPJA 3KRFA 3N0GA 4GAXA 3WCAA 5HN7A 4LOBA 4LFEA 5B0JA 1VG7A 3WCLA 3LLWA 4RXEA 5IM1A 5DIQF 5ER8A 1DI1A 2DH4A 4KKMA 3NF2A 5DHKA 4L2XF 1HM7A 3KB9A 5E8KA 3N3DA 3LJIA 1WMWA 3OYRA 4RXCA 4LZ3A 3RMGA 1WKZA 3P5PA 2ZCOA 2Q80A 3N1VF 4JZBA 1UBVA 2E8UA 5AHUB 3OACA 4PVYF 5IK0A 2E8VA 4KVDA 2H8OA 3Q2QA 3TFVA 2J1OA 1RQJA 3TS7A 4P0VA 3ICMA 4JXYA 3LK5A 3WCFA 2AZJA 3EGTA 3LGZB 3WEJA 3ICZA 3PYAA 4LPGF 2F7MF 2QISA 5HNAA 3S9VA 3ZMCA 5DZ2A 3CP6A 5DHIA 4LA6A 3UCAA 3KRPB 2F8ZF 3Q2ZA 4LLSA 3G4FA 3DYFA 2E92A 3ACYA 4OKMA 4NFIF 5IK6A 5CG6A 3WJOA 3N46F 2P1CA 3VJ8A 5ILZA 2AZLA 5DJVF 3TC1A 4JVJF 3ACWA 2F8CF 5B02A 4FJQA 3ICNA 3TFPA 2AELA 4KUXA 2J1PA 2ONHA 4LA5A 4XQTF 5IL3A 4LZCA 3AQCB 1HX9A 4LUUA 3RBMA 3N45F 3WCJA 3KBKA 3V1VA 4P0WA 1ZW5A 5DJPF 5IKHA 5EAUA 5IN8A 3VJAA 1HM4A 5B0MA 1KIYA 3BNXA 2OPMA 3N1WF 3P8LA 4DI5A 2Z4ZA 3VJ9A 1N23A 2OA6A 2E95A 5KSXF 2Q58A 3CKEA 3KRPA 3VJCA 4DXJA 3SDQA 3WEGA 2ONGA 1YYUA 4KQSA 4LFGA 1DGPA 3OABB 1N22A 1HXGA 2E8TA 4LTZA 2Q9ZA 3ADZA 5ILKA 3M0GA 4JXNA 4LIXA 5IMPA 3VJEA 3M01A 4GP2A 3AQ0A 4JZXA 1HXAA 5IMIA 2Z7IA 5IVGA 2E8XA 4KK2A 4LTVA 3LDWA 3KRAB 4EA1A 4E9UA 2FORA 4P0XA 1YYSA 1JFAA 1WL0A 5E8LA 2PS6A 2F9KF 2Z4XA 3WCDA 3AE0A 3S4JA 5H9DA 5ILYA 3WE9A 2E94A 5EASA 4EA0A 1WY0A 5JV1F 4LLTA 2E91A 4OKZA 3NPKA 3M9UA 5ERMA 3SDVA 1UBYA 5DGMF 4KWDA 5ILIA 4E1EA 1YQ7A 5B0IA 2RAHA 4XQSF 4HD1A 4KVIA 4OMGA 3WEHA 4RXDA 2J5CA 4KQ5A 2PS7A 1VG2A 3MZVA 2F94F 1V4HA 2Z52A 5IKAA 5IMNA 5C05A 3P8RA 3VJBA 2E93A 2OPNA 5JUZF 3G4DA 3BNYA 4ZQ8A 3WSAA 3EFQA 4K10A 1YYQA 3OABA 3WCEA 4DHDA 3N3LF 1KIZA 1WL3A 5HN8A 5JA0F 1YYTA 4GA3A 3P41A 3WJNA 5ERNA 4KVWA 4Q23A 5DW7A 3SDUA 3ZOUA 3KRAA 3N5HF 5B0KA 2E4OA 3ZL6A 3Q1OA 3SDTA 2Z50A 1WL1A 4GP1A 3QKCA 3Q30A 4QXSF 2ZCRA 4NKEA 4NKFA 3NRIA 4WK5A 4DEMF 3WCGA 1PS1A 1YHMA 2PS8A 4F6VA 5HN9A 3QQVA 1WL2A 3PKOA 3W7FA 1RTRA 3NPRA 3WEFA 4JYXA 4UMJA 3M02A 5I1UA 5AFXA 3ID0A 2Z4VA 1JFGA 3TFNA 5ILDA 2ZCQA 4F6XA 1VG6A 1V4EA 2E8WA 4KFAA 2Z7HA 2EWGA 3WCMA 5DGNF 3WC9A 4XQRF 3ICKA 5B01A 2PS4A 2ZEVA 3KROB 5B0LA 2Z78A 3PH7A 3N6KF 3DYHA 4RXAA 1EZFA 2Z4WA 3PYBA 2Q9YA 2Z4YA 3WCIA 5A0KA 2E90A 5EROA 3ACXA 5ILHA 3PDEA 3IBAA 3SDRA 1VG4A 2I19A 4NFKF 4DZWA 4RNQA 4F62A 4KVYA 5JV0F 2F89F 3N0FA 3V66A 4MC3A 3IPIA 3WCCA 1YYRA 4PVXF 2F92F 3APZA 5AYPA 4OMHA 3KRCB 3LMDA 1VG3A 5JV2F 1YHLA 4FP4A 3ASXA 2VF6A 1V4KA 2PS5A 5IK9A 2O1OA 3KRFB 5AELA 4LPHF 1FPSA 1YV5A 4NG6A 3V1XA 2OGDA 2ZCSA 4LFVF 4H5EF 4H5DF 5E8HA 3RYEA 3ZMBA 5DGSF 1RQIA 3KROA 4OGUA 4DWGA 4LZ0A 2AZKA 4MC0A 3RYWA 4MC8A 1HXCA 4KQUA 4LXWA 3LZ9A 3LOMA 3DYGA 3P5RA 3B7LA 3LSNA 4N1ZF 3WCBA 1N1ZA 5A0IA 2AETA 3CC9A 5B03A 4KPDA
chains in the Genus database with same CATH superfamily
3LVSA 3LGKA 4RYPA 5EATA 3N49F 3WEIA 3WCHA 1N1BA 5ILJA 3OACB 1N24A 3M00A 1YHKA 3LEEA 3SAEA 3WSBA 3LG5A 3EZ3A 3ZCDA 2ZEUA 5B00A 4EA2A 1YJ4A 1V4IA 2AEKA 5IL8A 2ZY1A 4E9ZA 3KRCA 3VJDA 3WJKA 4NUAA 4N9UA 5CG5A 5DJRF 3AQBB 4QPFA 4NFJF 2FTZA 5A0JA 1N20A 1N21A 1UBXA 3WEKA 1V4JA 1UBWA 3MAVA 4DWBA 3N5JF 4H5CF 4KPJA 3KRFA 3N0GA 4GAXA 3WCAA 5HN7A 4LOBA 4LFEA 5B0JA 1VG7A 3WCLA 3LLWA 4RXEA 5IM1A 5DIQF 5ER8A 1DI1A 2DH4A 4KKMA 3NF2A 5DHKA 4L2XF 1HM7A 3KB9A 5E8KA 3N3DA 3LJIA 1WMWA 3OYRA 4RXCA 4LZ3A 3RMGA 1WKZA 3P5PA 2ZCOA 2Q80A 3N1VF 4JZBA 1UBVA 2E8UA 5AHUB 3OACA 4PVYF 5IK0A 2E8VA 4KVDA 2H8OA 3Q2QA 3TFVA 2J1OA 1RQJA 3TS7A 4P0VA 3ICMA 4JXYA 3LK5A 3WCFA 2AZJA 3EGTA 3LGZB 3WEJA 3ICZA 3PYAA 4LPGF 2F7MF 2QISA 5HNAA 3S9VA 3ZMCA 5DZ2A 3CP6A 5DHIA 4LA6A 3UCAA 3KRPB 2F8ZF 3Q2ZA 4LLSA 3G4FA 3DYFA 2E92A 3ACYA 4OKMA 4NFIF 5IK6A 5CG6A 3WJOA 3N46F 2P1CA 3VJ8A 5ILZA 2AZLA 5DJVF 3TC1A 4JVJF 3ACWA 2F8CF 5B02A 4FJQA 3ICNA 3TFPA 2AELA 4KUXA 2J1PA 2ONHA 4LA5A 4XQTF 5IL3A 4LZCA 3AQCB 1HX9A 4LUUA 3RBMA 3N45F 3WCJA 3KBKA 3V1VA 4P0WA 1ZW5A 5DJPF 5IKHA 5EAUA 5IN8A 3VJAA 1HM4A 5B0MA 1KIYA 3BNXA 2OPMA 3N1WF 3P8LA 4DI5A 2Z4ZA 3VJ9A 1N23A 2OA6A 2E95A 5KSXF 2Q58A 3CKEA 3KRPA 3VJCA 4DXJA 3SDQA 3WEGA 2ONGA 1YYUA 4KQSA 4LFGA 1DGPA 3OABB 1N22A 1HXGA 2E8TA 4LTZA 2Q9ZA 3ADZA 5ILKA 3M0GA 4JXNA 4LIXA 5IMPA 3VJEA 3M01A 4GP2A 3AQ0A 4JZXA 1HXAA 5IMIA 2Z7IA 5IVGA 2E8XA 4KK2A 4LTVA 3LDWA 3KRAB 4EA1A 4E9UA 2FORA 4P0XA 1YYSA 1JFAA 1WL0A 5E8LA 2PS6A 2F9KF 2Z4XA 3WCDA 3AE0A 3S4JA 5H9DA 5ILYA 3WE9A 2E94A 5EASA 4EA0A 1WY0A 5JV1F 4LLTA 2E91A 4OKZA 3NPKA 3M9UA 5ERMA 3SDVA 1UBYA 5DGMF 4KWDA 5ILIA 4E1EA 1YQ7A 5B0IA 2RAHA 4XQSF 4HD1A 4KVIA 4OMGA 3WEHA 4RXDA 2J5CA 4KQ5A 2PS7A 1VG2A 3MZVA 2F94F 1V4HA 2Z52A 5IKAA 5IMNA 5C05A 3P8RA 3VJBA 2E93A 2OPNA 5JUZF 3G4DA 3BNYA 4ZQ8A 3WSAA 3EFQA 4K10A 1YYQA 3OABA 3WCEA 4DHDA 3N3LF 1KIZA 1WL3A 5HN8A 5JA0F 1YYTA 4GA3A 3P41A 3WJNA 5ERNA 4KVWA 4Q23A 5DW7A 3SDUA 3ZOUA 3KRAA 3N5HF 5B0KA 2E4OA 3ZL6A 3Q1OA 3SDTA 2Z50A 1WL1A 4GP1A 3QKCA 3Q30A 4QXSF 2ZCRA 4NKEA 4NKFA 3NRIA 4WK5A 4DEMF 3WCGA 1PS1A 1YHMA 2PS8A 4F6VA 5HN9A 3QQVA 1WL2A 3PKOA 3W7FA 1RTRA 3NPRA 3WEFA 4JYXA 4UMJA 3M02A 5I1UA 5AFXA 3ID0A 2Z4VA 1JFGA 3TFNA 5ILDA 2ZCQA 4F6XA 1VG6A 1V4EA 2E8WA 4KFAA 2Z7HA 2EWGA 3WCMA 5DGNF 3WC9A 4XQRF 3ICKA 5B01A 2PS4A 2ZEVA 3KROB 5B0LA 2Z78A 3PH7A 3N6KF 3DYHA 4RXAA 1EZFA 2Z4WA 3PYBA 2Q9YA 2Z4YA 3WCIA 5A0KA 2E90A 5EROA 3ACXA 5ILHA 3PDEA 3IBAA 3SDRA 1VG4A 2I19A 4NFKF 4DZWA 4RNQA 4F62A 4KVYA 5JV0F 2F89F 3N0FA 3V66A 4MC3A 3IPIA 3WCCA 1YYRA 4PVXF 2F92F 3APZA 5AYPA 4OMHA 3KRCB 3LMDA 1VG3A 5JV2F 1YHLA 4FP4A 3ASXA 2VF6A 1V4KA 2PS5A 5IK9A 2O1OA 3KRFB 5AELA 4LPHF 1FPSA 1YV5A 4NG6A 3V1XA 2OGDA 2ZCSA 4LFVF 4H5EF 4H5DF 5E8HA 3RYEA 3ZMBA 5DGSF 1RQIA 3KROA 4OGUA 4DWGA 4LZ0A 2AZKA 4MC0A 3RYWA 4MC8A 1HXCA 4KQUA 4LXWA 3LZ9A 3LOMA 3DYGA 3P5RA 3B7LA 3LSNA 4N1ZF 3WCBA 1N1ZA 5A0IA 2AETA 3CC9A 5B03A 4KPDA
chains in the Genus database with same CATH topology
3LVSA 3LGKA 4RYPA 5EATA 3N49F 3WEIA 3WCHA 1N1BA 5ILJA 3OACB 1N24A 3M00A 1YHKA 3LEEA 3SAEA 3WSBA 3LG5A 3EZ3A 3ZCDA 2ZEUA 5B00A 4EA2A 1YJ4A 1V4IA 2AEKA 5IL8A 2ZY1A 4E9ZA 3KRCA 3VJDA 3WJKA 4NUAA 4N9UA 5CG5A 5DJRF 3AQBB 4QPFA 4NFJF 2FTZA 5A0JA 1N20A 1N21A 1UBXA 3WEKA 1V4JA 1UBWA 3MAVA 4DWBA 3N5JF 4H5CF 4KPJA 3KRFA 3N0GA 4GAXA 3WCAA 5HN7A 4LOBA 4LFEA 5B0JA 1VG7A 3WCLA 3LLWA 4RXEA 5IM1A 5DIQF 5ER8A 1DI1A 2DH4A 4KKMA 3NF2A 5DHKA 4L2XF 1HM7A 3KB9A 5E8KA 3N3DA 3LJIA 1WMWA 3OYRA 4RXCA 4LZ3A 3RMGA 1WKZA 3P5PA 2ZCOA 2Q80A 3N1VF 4JZBA 1UBVA 2E8UA 5AHUB 3OACA 4PVYF 5IK0A 2E8VA 4KVDA 2H8OA 3Q2QA 3TFVA 2J1OA 1RQJA 3TS7A 4P0VA 3ICMA 4JXYA 3LK5A 3WCFA 2AZJA 3EGTA 3LGZB 3WEJA 3ICZA 3PYAA 4LPGF 2F7MF 2QISA 5HNAA 3S9VA 3ZMCA 5DZ2A 3CP6A 5DHIA 4LA6A 3UCAA 3KRPB 2F8ZF 3Q2ZA 4LLSA 3G4FA 3DYFA 2E92A 3ACYA 4OKMA 4NFIF 5IK6A 5CG6A 3WJOA 3N46F 2P1CA 3VJ8A 5ILZA 2AZLA 5DJVF 3TC1A 4JVJF 3ACWA 2F8CF 5B02A 4FJQA 3ICNA 3TFPA 2AELA 4KUXA 2J1PA 2ONHA 4LA5A 4XQTF 5IL3A 4LZCA 3AQCB 1HX9A 4LUUA 3RBMA 3N45F 3WCJA 3KBKA 3V1VA 4P0WA 1ZW5A 5DJPF 5IKHA 5EAUA 5IN8A 3VJAA 1HM4A 5B0MA 1KIYA 3BNXA 2OPMA 3N1WF 3P8LA 4DI5A 2Z4ZA 3VJ9A 1N23A 2OA6A 2E95A 5KSXF 2Q58A 3CKEA 3KRPA 3VJCA 4DXJA 3SDQA 3WEGA 2ONGA 1YYUA 4KQSA 4LFGA 1DGPA 3OABB 1N22A 1HXGA 2E8TA 4LTZA 2Q9ZA 3ADZA 5ILKA 3M0GA 4JXNA 4LIXA 5IMPA 3VJEA 3M01A 4GP2A 3AQ0A 4JZXA 1HXAA 5IMIA 2Z7IA 5IVGA 2E8XA 4KK2A 4LTVA 3LDWA 3KRAB 4EA1A 4E9UA 2FORA 4P0XA 1YYSA 1JFAA 1WL0A 5E8LA 2PS6A 2F9KF 2Z4XA 3WCDA 3AE0A 3S4JA 5H9DA 5ILYA 3WE9A 2E94A 5EASA 4EA0A 1WY0A 5JV1F 4LLTA 2E91A 4OKZA 3NPKA 3M9UA 5ERMA 3SDVA 1UBYA 5DGMF 4KWDA 5ILIA 4E1EA 1YQ7A 5B0IA 2RAHA 4XQSF 4HD1A 4KVIA 4OMGA 3WEHA 4RXDA 2J5CA 4KQ5A 2PS7A 1VG2A 3MZVA 2F94F 1V4HA 2Z52A 5IKAA 5IMNA 5C05A 3P8RA 3VJBA 2E93A 2OPNA 5JUZF 3G4DA 3BNYA 4ZQ8A 3WSAA 3EFQA 4K10A 1YYQA 3OABA 3WCEA 4DHDA 3N3LF 1KIZA 1WL3A 5HN8A 5JA0F 1YYTA 4GA3A 3P41A 3WJNA 5ERNA 4KVWA 4Q23A 5DW7A 3SDUA 3ZOUA 3KRAA 3N5HF 5B0KA 2E4OA 3ZL6A 3Q1OA 3SDTA 2Z50A 1WL1A 4GP1A 3QKCA 3Q30A 4QXSF 2ZCRA 4NKEA 4NKFA 3NRIA 4WK5A 4DEMF 3WCGA 1PS1A 1YHMA 2PS8A 4F6VA 5HN9A 3QQVA 1WL2A 3PKOA 3W7FA 1RTRA 3NPRA 3WEFA 4JYXA 4UMJA 3M02A 5I1UA 5AFXA 3ID0A 2Z4VA 1JFGA 3TFNA 5ILDA 2ZCQA 4F6XA 1VG6A 1V4EA 2E8WA 4KFAA 2Z7HA 2EWGA 3WCMA 5DGNF 3WC9A 4XQRF 3ICKA 5B01A 2PS4A 2ZEVA 3KROB 5B0LA 2Z78A 3PH7A 3N6KF 3DYHA 4RXAA 1EZFA 2Z4WA 3PYBA 2Q9YA 2Z4YA 3WCIA 5A0KA 2E90A 5EROA 3ACXA 5ILHA 3PDEA 3IBAA 3SDRA 1VG4A 2I19A 4NFKF 4DZWA 4RNQA 4F62A 4KVYA 5JV0F 2F89F 3N0FA 3V66A 4MC3A 3IPIA 3WCCA 1YYRA 4PVXF 2F92F 3APZA 5AYPA 4OMHA 3KRCB 3LMDA 1VG3A 5JV2F 1YHLA 4FP4A 3ASXA 2VF6A 1V4KA 2PS5A 5IK9A 2O1OA 3KRFB 5AELA 4LPHF 1FPSA 1YV5A 4NG6A 3V1XA 2OGDA 2ZCSA 4LFVF 4H5EF 4H5DF 5E8HA 3RYEA 3ZMBA 5DGSF 1RQIA 3KROA 4OGUA 4DWGA 4LZ0A 2AZKA 4MC0A 3RYWA 4MC8A 1HXCA 4KQUA 4LXWA 3LZ9A 3LOMA 3DYGA 3P5RA 3B7LA 3LSNA 4N1ZF 3WCBA 1N1ZA 5A0IA 2AETA 3CC9A 5B03A 4KPDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LVS A;  3LGK A;  4RYP A;  5EAT A;  3N49 F;  3WEI A;  3WCH A;  1N1B A;  5ILJ A;  3OAC B;  1N24 A;  3M00 A;  1YHK A;  3LEE A;  3SAE A;  3WSB A;  3LG5 A;  3EZ3 A;  3ZCD A;  2ZEU A;  5B00 A;  4EA2 A;  1YJ4 A;  1V4I A;  2AEK A;  5IL8 A;  2ZY1 A;  4E9Z A;  3KRC A;  3VJD A;  3WJK A;  4NUA A;  4N9U A;  5CG5 A;  5DJR F;  3AQB B;  4QPF A;  4NFJ F;  2FTZ A;  5A0J A;  1N20 A;  1N21 A;  1UBX A;  3WEK A;  1V4J A;  1UBW A;  3MAV A;  4DWB A;  3N5J F;  4H5C F;  4KPJ A;  3KRF A;  3N0G A;  4GAX A;  3WCA A;  5HN7 A;  4LOB A;  4LFE A;  5B0J A;  1VG7 A;  3WCL A;  3LLW A;  4RXE A;  5IM1 A;  5DIQ F;  5ER8 A;  1DI1 A;  2DH4 A;  4KKM A;  3NF2 A;  5DHK A;  4L2X F;  1HM7 A;  3KB9 A;  5E8K A;  3N3D A;  3LJI A;  1WMW A;  3OYR A;  4RXC A;  4LZ3 A;  3RMG A;  1WKZ A;  3P5P A;  2ZCO A;  2Q80 A;  3N1V F;  4JZB A;  1UBV A;  2E8U A;  5AHU B;  3OAC A;  4PVY F;  5IK0 A;  2E8V A;  4KVD A;  2H8O A;  3Q2Q A;  3TFV A;  2J1O A;  1RQJ A;  3TS7 A;  4P0V A;  3ICM A;  4JXY A;  3LK5 A;  3WCF A;  2AZJ A;  3EGT A;  3LGZ B;  3WEJ A;  3ICZ A;  3PYA A;  4LPG F;  2F7M F;  2QIS A;  5HNA A;  3S9V A;  3ZMC A;  5DZ2 A;  3CP6 A;  5DHI A;  4LA6 A;  3UCA A;  3KRP B;  2F8Z F;  3Q2Z A;  4LLS A;  3G4F A;  3DYF A;  2E92 A;  3ACY A;  4OKM A;  4NFI F;  5IK6 A;  5CG6 A;  3WJO A;  3N46 F;  2P1C A;  3VJ8 A;  5ILZ A;  2AZL A;  5DJV F;  3TC1 A;  4JVJ F;  3ACW A;  2F8C F;  5B02 A;  4FJQ A;  3ICN A;  3TFP A;  2AEL A;  4KUX A;  2J1P A;  2ONH A;  4LA5 A;  4XQT F;  5IL3 A;  4LZC A;  3AQC B;  1HX9 A;  4LUU A;  3RBM A;  3N45 F;  3WCJ A;  3KBK A;  3V1V A;  4P0W A;  1ZW5 A;  5DJP F;  5IKH A;  5EAU A;  5IN8 A;  3VJA A;  1HM4 A;  5B0M A;  1KIY A;  3BNX A;  2OPM A;  3N1W F;  3P8L A;  4DI5 A;  2Z4Z A;  3VJ9 A;  1N23 A;  2OA6 A;  2E95 A;  5KSX F;  2Q58 A;  3CKE A;  3KRP A;  3VJC A;  4DXJ A;  3SDQ A;  3WEG A;  2ONG A;  1YYU A;  4KQS A;  4LFG A;  1DGP A;  3OAB B;  1N22 A;  1HXG A;  2E8T A;  4LTZ A;  2Q9Z A;  3ADZ A;  5ILK A;  3M0G A;  4JXN A;  4LIX A;  5IMP A;  3VJE A;  3M01 A;  4GP2 A;  3AQ0 A;  4JZX A;  1HXA A;  5IMI A;  2Z7I A;  5IVG A;  2E8X A;  4KK2 A;  4LTV A;  3LDW A;  3KRA B;  4EA1 A;  4E9U A;  2FOR A;  4P0X A;  1YYS A;  1JFA A;  1WL0 A;  5E8L A;  2PS6 A;  2F9K F;  2Z4X A;  3WCD A;  3AE0 A;  3S4J A;  5H9D A;  5ILY A;  3WE9 A;  2E94 A;  5EAS A;  4EA0 A;  1WY0 A;  5JV1 F;  4LLT A;  2E91 A;  4OKZ A;  3NPK A;  3M9U A;  5ERM A;  3SDV A;  1UBY A;  5DGM F;  4KWD A;  5ILI A;  4E1E A;  1YQ7 A;  5B0I A;  2RAH A;  4XQS F;  4HD1 A;  4KVI A;  4OMG A;  3WEH A;  4RXD A;  2J5C A;  4KQ5 A;  2PS7 A;  1VG2 A;  3MZV A;  2F94 F;  1V4H A;  2Z52 A;  5IKA A;  5IMN A;  5C05 A;  3P8R A;  3VJB A;  2E93 A;  2OPN A;  5JUZ F;  3G4D A;  3BNY A;  4ZQ8 A;  3WSA A;  3EFQ A;  4K10 A;  1YYQ A;  3OAB A;  3WCE A;  4DHD A;  3N3L F;  1KIZ A;  1WL3 A;  5HN8 A;  5JA0 F;  1YYT A;  4GA3 A;  3P41 A;  3WJN A;  5ERN A;  4KVW A;  4Q23 A;  5DW7 A;  3SDU A;  3ZOU A;  3KRA A;  3N5H F;  5B0K A;  2E4O A;  3ZL6 A;  3Q1O A;  3SDT A;  2Z50 A;  1WL1 A;  4GP1 A;  3QKC A;  3Q30 A;  4QXS F;  2ZCR A;  4NKE A;  4NKF A;  3NRI A;  4WK5 A;  4DEM F;  3WCG A;  1PS1 A;  1YHM A;  2PS8 A;  4F6V A;  5HN9 A;  3QQV A;  1WL2 A;  3PKO A;  3W7F A;  1RTR A;  3NPR A;  3WEF A;  4JYX A;  4UMJ A;  3M02 A;  5I1U A;  5AFX A;  3ID0 A;  2Z4V A;  1JFG A;  3TFN A;  5ILD A;  2ZCQ A;  4F6X A;  1VG6 A;  1V4E A;  2E8W A;  4KFA A;  2Z7H A;  2EWG A;  3WCM A;  5DGN F;  3WC9 A;  4XQR F;  3ICK A;  5B01 A;  2PS4 A;  2ZEV A;  3KRO B;  5B0L A;  2Z78 A;  3PH7 A;  3N6K F;  3DYH A;  4RXA A;  1EZF A;  2Z4W A;  3PYB A;  2Q9Y A;  2Z4Y A;  3WCI A;  5A0K A;  2E90 A;  5ERO A;  3ACX A;  5ILH A;  3PDE A;  3IBA A;  3SDR A;  1VG4 A;  2I19 A;  4NFK F;  4DZW A;  4RNQ A;  4F62 A;  4KVY A;  5JV0 F;  2F89 F;  3N0F A;  3V66 A;  4MC3 A;  3IPI A;  3WCC A;  1YYR A;  4PVX F;  2F92 F;  3APZ A;  5AYP A;  4OMH A;  3KRC B;  3LMD A;  1VG3 A;  5JV2 F;  1YHL A;  4FP4 A;  3ASX A;  2VF6 A;  1V4K A;  2PS5 A;  5IK9 A;  2O1O A;  3KRF B;  5AEL A;  4LPH F;  1FPS A;  1YV5 A;  4NG6 A;  3V1X A;  2OGD A;  2ZCS A;  4LFV F;  4H5E F;  4H5D F;  5E8H A;  3RYE A;  3ZMB A;  5DGS F;  1RQI A;  3KRO A;  4OGU A;  4DWG A;  4LZ0 A;  2AZK A;  4MC0 A;  3RYW A;  4MC8 A;  1HXC A;  4KQU A;  4LXW A;  3LZ9 A;  3LOM A;  3DYG A;  3P5R A;  3B7L A;  3LSN A;  4N1Z F;  3WCB A;  1N1Z A;  5A0I A;  2AET A;  3CC9 A;  5B03 A;  4KPD A; 
#chains in the Genus database with same CATH topology
 3LVS A;  3LGK A;  4RYP A;  5EAT A;  3N49 F;  3WEI A;  3WCH A;  1N1B A;  5ILJ A;  3OAC B;  1N24 A;  3M00 A;  1YHK A;  3LEE A;  3SAE A;  3WSB A;  3LG5 A;  3EZ3 A;  3ZCD A;  2ZEU A;  5B00 A;  4EA2 A;  1YJ4 A;  1V4I A;  2AEK A;  5IL8 A;  2ZY1 A;  4E9Z A;  3KRC A;  3VJD A;  3WJK A;  4NUA A;  4N9U A;  5CG5 A;  5DJR F;  3AQB B;  4QPF A;  4NFJ F;  2FTZ A;  5A0J A;  1N20 A;  1N21 A;  1UBX A;  3WEK A;  1V4J A;  1UBW A;  3MAV A;  4DWB A;  3N5J F;  4H5C F;  4KPJ A;  3KRF A;  3N0G A;  4GAX A;  3WCA A;  5HN7 A;  4LOB A;  4LFE A;  5B0J A;  1VG7 A;  3WCL A;  3LLW A;  4RXE A;  5IM1 A;  5DIQ F;  5ER8 A;  1DI1 A;  2DH4 A;  4KKM A;  3NF2 A;  5DHK A;  4L2X F;  1HM7 A;  3KB9 A;  5E8K A;  3N3D A;  3LJI A;  1WMW A;  3OYR A;  4RXC A;  4LZ3 A;  3RMG A;  1WKZ A;  3P5P A;  2ZCO A;  2Q80 A;  3N1V F;  4JZB A;  1UBV A;  2E8U A;  5AHU B;  3OAC A;  4PVY F;  5IK0 A;  2E8V A;  4KVD A;  2H8O A;  3Q2Q A;  3TFV A;  2J1O A;  1RQJ A;  3TS7 A;  4P0V A;  3ICM A;  4JXY A;  3LK5 A;  3WCF A;  2AZJ A;  3EGT A;  3LGZ B;  3WEJ A;  3ICZ A;  3PYA A;  4LPG F;  2F7M F;  2QIS A;  5HNA A;  3S9V A;  3ZMC A;  5DZ2 A;  3CP6 A;  5DHI A;  4LA6 A;  3UCA A;  3KRP B;  2F8Z F;  3Q2Z A;  4LLS A;  3G4F A;  3DYF A;  2E92 A;  3ACY A;  4OKM A;  4NFI F;  5IK6 A;  5CG6 A;  3WJO A;  3N46 F;  2P1C A;  3VJ8 A;  5ILZ A;  2AZL A;  5DJV F;  3TC1 A;  4JVJ F;  3ACW A;  2F8C F;  5B02 A;  4FJQ A;  3ICN A;  3TFP A;  2AEL A;  4KUX A;  2J1P A;  2ONH A;  4LA5 A;  4XQT F;  5IL3 A;  4LZC A;  3AQC B;  1HX9 A;  4LUU A;  3RBM A;  3N45 F;  3WCJ A;  3KBK A;  3V1V A;  4P0W A;  1ZW5 A;  5DJP F;  5IKH A;  5EAU A;  5IN8 A;  3VJA A;  1HM4 A;  5B0M A;  1KIY A;  3BNX A;  2OPM A;  3N1W F;  3P8L A;  4DI5 A;  2Z4Z A;  3VJ9 A;  1N23 A;  2OA6 A;  2E95 A;  5KSX F;  2Q58 A;  3CKE A;  3KRP A;  3VJC A;  4DXJ A;  3SDQ A;  3WEG A;  2ONG A;  1YYU A;  4KQS A;  4LFG A;  1DGP A;  3OAB B;  1N22 A;  1HXG A;  2E8T A;  4LTZ A;  2Q9Z A;  3ADZ A;  5ILK A;  3M0G A;  4JXN A;  4LIX A;  5IMP A;  3VJE A;  3M01 A;  4GP2 A;  3AQ0 A;  4JZX A;  1HXA A;  5IMI A;  2Z7I A;  5IVG A;  2E8X A;  4KK2 A;  4LTV A;  3LDW A;  3KRA B;  4EA1 A;  4E9U A;  2FOR A;  4P0X A;  1YYS A;  1JFA A;  1WL0 A;  5E8L A;  2PS6 A;  2F9K F;  2Z4X A;  3WCD A;  3AE0 A;  3S4J A;  5H9D A;  5ILY A;  3WE9 A;  2E94 A;  5EAS A;  4EA0 A;  1WY0 A;  5JV1 F;  4LLT A;  2E91 A;  4OKZ A;  3NPK A;  3M9U A;  5ERM A;  3SDV A;  1UBY A;  5DGM F;  4KWD A;  5ILI A;  4E1E A;  1YQ7 A;  5B0I A;  2RAH A;  4XQS F;  4HD1 A;  4KVI A;  4OMG A;  3WEH A;  4RXD A;  2J5C A;  4KQ5 A;  2PS7 A;  1VG2 A;  3MZV A;  2F94 F;  1V4H A;  2Z52 A;  5IKA A;  5IMN A;  5C05 A;  3P8R A;  3VJB A;  2E93 A;  2OPN A;  5JUZ F;  3G4D A;  3BNY A;  4ZQ8 A;  3WSA A;  3EFQ A;  4K10 A;  1YYQ A;  3OAB A;  3WCE A;  4DHD A;  3N3L F;  1KIZ A;  1WL3 A;  5HN8 A;  5JA0 F;  1YYT A;  4GA3 A;  3P41 A;  3WJN A;  5ERN A;  4KVW A;  4Q23 A;  5DW7 A;  3SDU A;  3ZOU A;  3KRA A;  3N5H F;  5B0K A;  2E4O A;  3ZL6 A;  3Q1O A;  3SDT A;  2Z50 A;  1WL1 A;  4GP1 A;  3QKC A;  3Q30 A;  4QXS F;  2ZCR A;  4NKE A;  4NKF A;  3NRI A;  4WK5 A;  4DEM F;  3WCG A;  1PS1 A;  1YHM A;  2PS8 A;  4F6V A;  5HN9 A;  3QQV A;  1WL2 A;  3PKO A;  3W7F A;  1RTR A;  3NPR A;  3WEF A;  4JYX A;  4UMJ A;  3M02 A;  5I1U A;  5AFX A;  3ID0 A;  2Z4V A;  1JFG A;  3TFN A;  5ILD A;  2ZCQ A;  4F6X A;  1VG6 A;  1V4E A;  2E8W A;  4KFA A;  2Z7H A;  2EWG A;  3WCM A;  5DGN F;  3WC9 A;  4XQR F;  3ICK A;  5B01 A;  2PS4 A;  2ZEV A;  3KRO B;  5B0L A;  2Z78 A;  3PH7 A;  3N6K F;  3DYH A;  4RXA A;  1EZF A;  2Z4W A;  3PYB A;  2Q9Y A;  2Z4Y A;  3WCI A;  5A0K A;  2E90 A;  5ERO A;  3ACX A;  5ILH A;  3PDE A;  3IBA A;  3SDR A;  1VG4 A;  2I19 A;  4NFK F;  4DZW A;  4RNQ A;  4F62 A;  4KVY A;  5JV0 F;  2F89 F;  3N0F A;  3V66 A;  4MC3 A;  3IPI A;  3WCC A;  1YYR A;  4PVX F;  2F92 F;  3APZ A;  5AYP A;  4OMH A;  3KRC B;  3LMD A;  1VG3 A;  5JV2 F;  1YHL A;  4FP4 A;  3ASX A;  2VF6 A;  1V4K A;  2PS5 A;  5IK9 A;  2O1O A;  3KRF B;  5AEL A;  4LPH F;  1FPS A;  1YV5 A;  4NG6 A;  3V1X A;  2OGD A;  2ZCS A;  4LFV F;  4H5E F;  4H5D F;  5E8H A;  3RYE A;  3ZMB A;  5DGS F;  1RQI A;  3KRO A;  4OGU A;  4DWG A;  4LZ0 A;  2AZK A;  4MC0 A;  3RYW A;  4MC8 A;  1HXC A;  4KQU A;  4LXW A;  3LZ9 A;  3LOM A;  3DYG A;  3P5R A;  3B7L A;  3LSN A;  4N1Z F;  3WCB A;  1N1Z A;  5A0I A;  2AET A;  3CC9 A;  5B03 A;  4KPD A; 
#chains in the Genus database with same CATH homology
 3LVS A;  3LGK A;  4RYP A;  5EAT A;  3N49 F;  3WEI A;  3WCH A;  1N1B A;  5ILJ A;  3OAC B;  1N24 A;  3M00 A;  1YHK A;  3LEE A;  3SAE A;  3WSB A;  3LG5 A;  3EZ3 A;  3ZCD A;  2ZEU A;  5B00 A;  4EA2 A;  1YJ4 A;  1V4I A;  2AEK A;  5IL8 A;  2ZY1 A;  4E9Z A;  3KRC A;  3VJD A;  3WJK A;  4NUA A;  4N9U A;  5CG5 A;  5DJR F;  3AQB B;  4QPF A;  4NFJ F;  2FTZ A;  5A0J A;  1N20 A;  1N21 A;  1UBX A;  3WEK A;  1V4J A;  1UBW A;  3MAV A;  4DWB A;  3N5J F;  4H5C F;  4KPJ A;  3KRF A;  3N0G A;  4GAX A;  3WCA A;  5HN7 A;  4LOB A;  4LFE A;  5B0J A;  1VG7 A;  3WCL A;  3LLW A;  4RXE A;  5IM1 A;  5DIQ F;  5ER8 A;  1DI1 A;  2DH4 A;  4KKM A;  3NF2 A;  5DHK A;  4L2X F;  1HM7 A;  3KB9 A;  5E8K A;  3N3D A;  3LJI A;  1WMW A;  3OYR A;  4RXC A;  4LZ3 A;  3RMG A;  1WKZ A;  3P5P A;  2ZCO A;  2Q80 A;  3N1V F;  4JZB A;  1UBV A;  2E8U A;  5AHU B;  3OAC A;  4PVY F;  5IK0 A;  2E8V A;  4KVD A;  2H8O A;  3Q2Q A;  3TFV A;  2J1O A;  1RQJ A;  3TS7 A;  4P0V A;  3ICM A;  4JXY A;  3LK5 A;  3WCF A;  2AZJ A;  3EGT A;  3LGZ B;  3WEJ A;  3ICZ A;  3PYA A;  4LPG F;  2F7M F;  2QIS A;  5HNA A;  3S9V A;  3ZMC A;  5DZ2 A;  3CP6 A;  5DHI A;  4LA6 A;  3UCA A;  3KRP B;  2F8Z F;  3Q2Z A;  4LLS A;  3G4F A;  3DYF A;  2E92 A;  3ACY A;  4OKM A;  4NFI F;  5IK6 A;  5CG6 A;  3WJO A;  3N46 F;  2P1C A;  3VJ8 A;  5ILZ A;  2AZL A;  5DJV F;  3TC1 A;  4JVJ F;  3ACW A;  2F8C F;  5B02 A;  4FJQ A;  3ICN A;  3TFP A;  2AEL A;  4KUX A;  2J1P A;  2ONH A;  4LA5 A;  4XQT F;  5IL3 A;  4LZC A;  3AQC B;  1HX9 A;  4LUU A;  3RBM A;  3N45 F;  3WCJ A;  3KBK A;  3V1V A;  4P0W A;  1ZW5 A;  5DJP F;  5IKH A;  5EAU A;  5IN8 A;  3VJA A;  1HM4 A;  5B0M A;  1KIY A;  3BNX A;  2OPM A;  3N1W F;  3P8L A;  4DI5 A;  2Z4Z A;  3VJ9 A;  1N23 A;  2OA6 A;  2E95 A;  5KSX F;  2Q58 A;  3CKE A;  3KRP A;  3VJC A;  4DXJ A;  3SDQ A;  3WEG A;  2ONG A;  1YYU A;  4KQS A;  4LFG A;  1DGP A;  3OAB B;  1N22 A;  1HXG A;  2E8T A;  4LTZ A;  2Q9Z A;  3ADZ A;  5ILK A;  3M0G A;  4JXN A;  4LIX A;  5IMP A;  3VJE A;  3M01 A;  4GP2 A;  3AQ0 A;  4JZX A;  1HXA A;  5IMI A;  2Z7I A;  5IVG A;  2E8X A;  4KK2 A;  4LTV A;  3LDW A;  3KRA B;  4EA1 A;  4E9U A;  2FOR A;  4P0X A;  1YYS A;  1JFA A;  1WL0 A;  5E8L A;  2PS6 A;  2F9K F;  2Z4X A;  3WCD A;  3AE0 A;  3S4J A;  5H9D A;  5ILY A;  3WE9 A;  2E94 A;  5EAS A;  4EA0 A;  1WY0 A;  5JV1 F;  4LLT A;  2E91 A;  4OKZ A;  3NPK A;  3M9U A;  5ERM A;  3SDV A;  1UBY A;  5DGM F;  4KWD A;  5ILI A;  4E1E A;  1YQ7 A;  5B0I A;  2RAH A;  4XQS F;  4HD1 A;  4KVI A;  4OMG A;  3WEH A;  4RXD A;  2J5C A;  4KQ5 A;  2PS7 A;  1VG2 A;  3MZV A;  2F94 F;  1V4H A;  2Z52 A;  5IKA A;  5IMN A;  5C05 A;  3P8R A;  3VJB A;  2E93 A;  2OPN A;  5JUZ F;  3G4D A;  3BNY A;  4ZQ8 A;  3WSA A;  3EFQ A;  4K10 A;  1YYQ A;  3OAB A;  3WCE A;  4DHD A;  3N3L F;  1KIZ A;  1WL3 A;  5HN8 A;  5JA0 F;  1YYT A;  4GA3 A;  3P41 A;  3WJN A;  5ERN A;  4KVW A;  4Q23 A;  5DW7 A;  3SDU A;  3ZOU A;  3KRA A;  3N5H F;  5B0K A;  2E4O A;  3ZL6 A;  3Q1O A;  3SDT A;  2Z50 A;  1WL1 A;  4GP1 A;  3QKC A;  3Q30 A;  4QXS F;  2ZCR A;  4NKE A;  4NKF A;  3NRI A;  4WK5 A;  4DEM F;  3WCG A;  1PS1 A;  1YHM A;  2PS8 A;  4F6V A;  5HN9 A;  3QQV A;  1WL2 A;  3PKO A;  3W7F A;  1RTR A;  3NPR A;  3WEF A;  4JYX A;  4UMJ A;  3M02 A;  5I1U A;  5AFX A;  3ID0 A;  2Z4V A;  1JFG A;  3TFN A;  5ILD A;  2ZCQ A;  4F6X A;  1VG6 A;  1V4E A;  2E8W A;  4KFA A;  2Z7H A;  2EWG A;  3WCM A;  5DGN F;  3WC9 A;  4XQR F;  3ICK A;  5B01 A;  2PS4 A;  2ZEV A;  3KRO B;  5B0L A;  2Z78 A;  3PH7 A;  3N6K F;  3DYH A;  4RXA A;  1EZF A;  2Z4W A;  3PYB A;  2Q9Y A;  2Z4Y A;  3WCI A;  5A0K A;  2E90 A;  5ERO A;  3ACX A;  5ILH A;  3PDE A;  3IBA A;  3SDR A;  1VG4 A;  2I19 A;  4NFK F;  4DZW A;  4RNQ A;  4F62 A;  4KVY A;  5JV0 F;  2F89 F;  3N0F A;  3V66 A;  4MC3 A;  3IPI A;  3WCC A;  1YYR A;  4PVX F;  2F92 F;  3APZ A;  5AYP A;  4OMH A;  3KRC B;  3LMD A;  1VG3 A;  5JV2 F;  1YHL A;  4FP4 A;  3ASX A;  2VF6 A;  1V4K A;  2PS5 A;  5IK9 A;  2O1O A;  3KRF B;  5AEL A;  4LPH F;  1FPS A;  1YV5 A;  4NG6 A;  3V1X A;  2OGD A;  2ZCS A;  4LFV F;  4H5E F;  4H5D F;  5E8H A;  3RYE A;  3ZMB A;  5DGS F;  1RQI A;  3KRO A;  4OGU A;  4DWG A;  4LZ0 A;  2AZK A;  4MC0 A;  3RYW A;  4MC8 A;  1HXC A;  4KQU A;  4LXW A;  3LZ9 A;  3LOM A;  3DYG A;  3P5R A;  3B7L A;  3LSN A;  4N1Z F;  3WCB A;  1N1Z A;  5A0I A;  2AET A;  3CC9 A;  5B03 A;  4KPD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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