4RXAA

Crystal structure of human farnesyl diphosphate synthase in complex with bph-1358
Total Genus 123
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
123
sequence length
339
structure length
330
Chain Sequence
QEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQIKENYGQVAVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Farnesyl pyrophosphate synthase
publication title Farnesyl diphosphate synthase inhibitors with unique ligand-binding geometries.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 123
structure length 330
sequence length 339
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2014-12-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4rxaA00
3PDEA 2ZCSA 5ERNA 5B0JA 3EZ3A 5B03A 5JUZF 5ILIA 2ZY1A 1N23A 2OPMA 1N24A 4KVIA 5EASA 4LTVA 3N46F 2PS5A 4LLTA 3N6KF 3SDVA 3AQBB 4JYXA 4KK2A 3NPRA 3N49F 3M00A 1WL2A 4H5DF 3LJIA 5DW7A 3KB9A 5DHKA 3WCBA 4NKEA 4RXAA 3N5JF 5IVGA 3RBMA 5KSXF 1WKZA 4PVXF 4EA0A 1UBYA 2OPNA 3ICNA 3N5HF 4GP1A 5IL3A 5A0KA 3Q1OA 3KRFB 1KIYA 3PH7A 4LFGA 3VJAA 3OACB 4NKFA 1JFGA 3WEKA 3CC9A 4LUUA 5A0JA 2J1PA 3SDUA 2AETA 3LDWA 2EWGA 4JVJF 4DWBA 1V4JA 4MC3A 4OMGA 5IK0A 2ZCRA 3WCFA 4KQ5A 4P0WA 2F9KF 3OABA 3G4DA 4LPHF 3BNYA 4KUXA 2Z7IA 3SDRA 2F8CF 3KROB 1HX9A 3APZA 4KKMA 2AZJA 4KQUA 5DGMF 5JA0F 3ACXA 3WCDA 1DGPA 3WCGA 2E8UA 2E94A 4MC0A 3PYAA 4OKZA 3Q30A 1WL1A 3LVSA 2PS6A 3LG5A 5DGSF 4LZ0A 3WEHA 4UMJA 3EFQA 1JFAA 4MC8A 3TFPA 1VG4A 2Z4YA 3OABB 5AELA 4KWDA 2Z7HA 1YYTA 4LXWA 3LK5A 3V1VA 5EROA 5ERMA 3ZMBA 3M02A 3SDQA 1KIZA 2AZLA 4GA3A 3AQCB 3SDTA 5IMPA 3VJBA 2RAHA 3N3DA 3IBAA 3WE9A 4E9ZA 3WCLA 3DYFA 3N3LF 3RYWA 1V4IA 4H5CF 2I19A 3KRFA 3WC9A 2F94F 4NUAA 1EZFA 2E95A 3KRAA 3OACA 3WEFA 5AFXA 2Z4XA 4N9UA 2Z4ZA 4OKMA 5DJPF 2F7MF 4KVDA 3WCCA 2Q9ZA 5JV0F 2AEKA 5DGNF 5IK6A 4H5EF 5ILDA 3KRCA 4LZCA 4ZQ8A 4QPFA 3LOMA 4LOBA 1HXGA 1YQ7A 3RMGA 1WMWA 4KQSA 1WL0A 3KROA 3MAVA 4KFAA 3KRAB 5B00A 3NRIA 3KBKA 4KVYA 3TFNA 1VG7A 2E4OA 2H8OA 3ZL6A 3LGKA 1FPSA 5EATA 3M01A 2E93A 4Q23A 1YV5A 1N20A 3CP6A 4F62A 3P5PA 3WCAA 2E8TA 5HN7A 5IKHA 1WL3A 3KRCB 2OA6A 2PS7A 4DHDA 3AQ0A 2ONGA 5I1UA 3B7LA 3G4FA 5E8HA 4LA5A 4JXYA 2F92F 3IPIA 3P5RA 4JZXA 4NFIF 4DI5A 3QQVA 4LLSA 3WSBA 5EAUA 3WCJA 3WCMA 1WY0A 2F8ZF 2Z52A 5ILYA 3M0GA 1RTRA 2PS4A 3Q2QA 3TFVA 4DXJA 4LFEA 1RQIA 3PKOA 3AE0A 5E8LA 2OGDA 4E9UA 1RQJA 3EGTA 3DYGA 3WCEA 1DI1A 3W7FA 5IM1A 4RNQA 5ILJA 4JXNA 4RXCA 3N0GA 5IK9A 4FP4A 3N1VF 1ZW5A 4GP2A 2Q58A 4QXSF 2VF6A 5IL8A 3WEJA 5C05A 1V4KA 2AZKA 2QISA 3KRPA 2DH4A 1HM7A 3CKEA 3NF2A 2E8WA 4LPGF 5B0IA 3ZMCA 5B0MA 1YYRA 2ONHA 2Z78A 3BNXA 3NPKA 4XQRF 4KPJA 3WEIA 1YYSA 2P1CA 3WEGA 1N22A 4DEMF 3ZOUA 2E8VA 3ICMA 4N1ZF 5JV1F 2Z50A 2ZCOA 5DIQF 3VJDA 3MZVA 1N21A 2E91A 4P0XA 3TC1A 1V4HA 4RXDA 4JZBA 3ACYA 4DWGA 5B0KA 3PYBA 1HM4A 1V4EA 3LZ9A 4P0VA 2ZEUA 3KRPB 3QKCA 5ER8A 4NG6A 4OMHA 3SAEA 4LZ3A 1YYUA 2E8XA 2J1OA 4KPDA 4XQSF 2E92A 5DZ2A 1N1ZA 2J5CA 3RYEA 4EA2A 1UBXA 3DYHA 2F89F 5ILKA 2E90A 5AHUB 4F6XA 5E8KA 2ZCQA 3LSNA 3ACWA 3LMDA 1UBWA 2Q9YA 5ILZA 4XQTF 4GAXA 4EA1A 5ILHA 3WJOA 2Z4WA 5CG6A 4RYPA 2Z4VA 3LGZB 1YHKA 1VG3A 3TS7A 2FTZA 1N1BA 2PS8A 5H9DA 2AELA 3VJ8A 2FORA 3P8RA 3S9VA 3N0FA 3LLWA 3ZCDA 3N1WF 1HXCA 5B01A 1PS1A 5IMIA 3WCIA 5JV2F 5HN9A 4F6VA 4NFKF 4LTZA 1YHMA 4L2XF 5DHIA 1YHLA 4LFVF 4FJQA 3Q2ZA 3P8LA 3ICKA 2O1OA 4NFJF 3V66A 4KVWA 3S4JA 3UCAA 4E1EA 5AYPA 3WJNA 3VJ9A 4PVYF 2ZEVA 3N45F 1HXAA 3P41A 1YJ4A 1VG2A 5B02A 3WJKA 1VG6A 5A0IA 5IMNA 3LEEA 3WCHA 3M9UA 5B0LA 5DJVF 2Q80A 3ASXA 5HN8A 3VJEA 4DZWA 4WK5A 5IN8A 5CG5A 5HNAA 4LIXA 3OYRA 4RXEA 3ADZA 3VJCA 1UBVA 4OGUA 4HD1A 3WSAA 5DJRF 3V1XA 4LA6A 5IKAA 1YYQA 3ICZA 4K10A 3ID0A
chains in the Genus database with same CATH superfamily
3PDEA 2ZCSA 5ERNA 5B0JA 3EZ3A 5B03A 5JUZF 5ILIA 2ZY1A 1N23A 2OPMA 1N24A 4KVIA 5EASA 4LTVA 3N46F 2PS5A 4LLTA 3N6KF 3SDVA 3AQBB 4JYXA 4KK2A 3NPRA 3N49F 3M00A 1WL2A 4H5DF 3LJIA 5DW7A 3KB9A 5DHKA 3WCBA 4NKEA 4RXAA 3N5JF 5IVGA 3RBMA 5KSXF 1WKZA 4PVXF 4EA0A 1UBYA 2OPNA 3ICNA 3N5HF 4GP1A 5IL3A 5A0KA 3Q1OA 3KRFB 1KIYA 3PH7A 4LFGA 3VJAA 3OACB 4NKFA 1JFGA 3WEKA 3CC9A 4LUUA 5A0JA 2J1PA 3SDUA 2AETA 3LDWA 2EWGA 4JVJF 4DWBA 1V4JA 4MC3A 4OMGA 5IK0A 2ZCRA 3WCFA 4KQ5A 4P0WA 2F9KF 3OABA 3G4DA 4LPHF 3BNYA 4KUXA 2Z7IA 3SDRA 2F8CF 3KROB 1HX9A 3APZA 4KKMA 2AZJA 4KQUA 5DGMF 5JA0F 3ACXA 3WCDA 1DGPA 3WCGA 2E8UA 2E94A 4MC0A 3PYAA 4OKZA 3Q30A 1WL1A 3LVSA 2PS6A 3LG5A 5DGSF 4LZ0A 3WEHA 4UMJA 3EFQA 1JFAA 4MC8A 3TFPA 1VG4A 2Z4YA 3OABB 5AELA 4KWDA 2Z7HA 1YYTA 4LXWA 3LK5A 3V1VA 5EROA 5ERMA 3ZMBA 3M02A 3SDQA 1KIZA 2AZLA 4GA3A 3AQCB 3SDTA 5IMPA 3VJBA 2RAHA 3N3DA 3IBAA 3WE9A 4E9ZA 3WCLA 3DYFA 3N3LF 3RYWA 1V4IA 4H5CF 2I19A 3KRFA 3WC9A 2F94F 4NUAA 1EZFA 2E95A 3KRAA 3OACA 3WEFA 5AFXA 2Z4XA 4N9UA 2Z4ZA 4OKMA 5DJPF 2F7MF 4KVDA 3WCCA 2Q9ZA 5JV0F 2AEKA 5DGNF 5IK6A 4H5EF 5ILDA 3KRCA 4LZCA 4ZQ8A 4QPFA 3LOMA 4LOBA 1HXGA 1YQ7A 3RMGA 1WMWA 4KQSA 1WL0A 3KROA 3MAVA 4KFAA 3KRAB 5B00A 3NRIA 3KBKA 4KVYA 3TFNA 1VG7A 2E4OA 2H8OA 3ZL6A 3LGKA 1FPSA 5EATA 3M01A 2E93A 4Q23A 1YV5A 1N20A 3CP6A 4F62A 3P5PA 3WCAA 2E8TA 5HN7A 5IKHA 1WL3A 3KRCB 2OA6A 2PS7A 4DHDA 3AQ0A 2ONGA 5I1UA 3B7LA 3G4FA 5E8HA 4LA5A 4JXYA 2F92F 3IPIA 3P5RA 4JZXA 4NFIF 4DI5A 3QQVA 4LLSA 3WSBA 5EAUA 3WCJA 3WCMA 1WY0A 2F8ZF 2Z52A 5ILYA 3M0GA 1RTRA 2PS4A 3Q2QA 3TFVA 4DXJA 4LFEA 1RQIA 3PKOA 3AE0A 5E8LA 2OGDA 4E9UA 1RQJA 3EGTA 3DYGA 3WCEA 1DI1A 3W7FA 5IM1A 4RNQA 5ILJA 4JXNA 4RXCA 3N0GA 5IK9A 4FP4A 3N1VF 1ZW5A 4GP2A 2Q58A 4QXSF 2VF6A 5IL8A 3WEJA 5C05A 1V4KA 2AZKA 2QISA 3KRPA 2DH4A 1HM7A 3CKEA 3NF2A 2E8WA 4LPGF 5B0IA 3ZMCA 5B0MA 1YYRA 2ONHA 2Z78A 3BNXA 3NPKA 4XQRF 4KPJA 3WEIA 1YYSA 2P1CA 3WEGA 1N22A 4DEMF 3ZOUA 2E8VA 3ICMA 4N1ZF 5JV1F 2Z50A 2ZCOA 5DIQF 3VJDA 3MZVA 1N21A 2E91A 4P0XA 3TC1A 1V4HA 4RXDA 4JZBA 3ACYA 4DWGA 5B0KA 3PYBA 1HM4A 1V4EA 3LZ9A 4P0VA 2ZEUA 3KRPB 3QKCA 5ER8A 4NG6A 4OMHA 3SAEA 4LZ3A 1YYUA 2E8XA 2J1OA 4KPDA 4XQSF 2E92A 5DZ2A 1N1ZA 2J5CA 3RYEA 4EA2A 1UBXA 3DYHA 2F89F 5ILKA 2E90A 5AHUB 4F6XA 5E8KA 2ZCQA 3LSNA 3ACWA 3LMDA 1UBWA 2Q9YA 5ILZA 4XQTF 4GAXA 4EA1A 5ILHA 3WJOA 2Z4WA 5CG6A 4RYPA 2Z4VA 3LGZB 1YHKA 1VG3A 3TS7A 2FTZA 1N1BA 2PS8A 5H9DA 2AELA 3VJ8A 2FORA 3P8RA 3S9VA 3N0FA 3LLWA 3ZCDA 3N1WF 1HXCA 5B01A 1PS1A 5IMIA 3WCIA 5JV2F 5HN9A 4F6VA 4NFKF 4LTZA 1YHMA 4L2XF 5DHIA 1YHLA 4LFVF 4FJQA 3Q2ZA 3P8LA 3ICKA 2O1OA 4NFJF 3V66A 4KVWA 3S4JA 3UCAA 4E1EA 5AYPA 3WJNA 3VJ9A 4PVYF 2ZEVA 3N45F 1HXAA 3P41A 1YJ4A 1VG2A 5B02A 3WJKA 1VG6A 5A0IA 5IMNA 3LEEA 3WCHA 3M9UA 5B0LA 5DJVF 2Q80A 3ASXA 5HN8A 3VJEA 4DZWA 4WK5A 5IN8A 5CG5A 5HNAA 4LIXA 3OYRA 4RXEA 3ADZA 3VJCA 1UBVA 4OGUA 4HD1A 3WSAA 5DJRF 3V1XA 4LA6A 5IKAA 1YYQA 3ICZA 4K10A 3ID0A
chains in the Genus database with same CATH topology
3PDEA 2ZCSA 5ERNA 5B0JA 3EZ3A 5B03A 5JUZF 5ILIA 2ZY1A 1N23A 2OPMA 1N24A 4KVIA 5EASA 4LTVA 3N46F 2PS5A 4LLTA 3N6KF 3SDVA 3AQBB 4JYXA 4KK2A 3NPRA 3N49F 3M00A 1WL2A 4H5DF 3LJIA 5DW7A 3KB9A 5DHKA 3WCBA 4NKEA 4RXAA 3N5JF 5IVGA 3RBMA 5KSXF 1WKZA 4PVXF 4EA0A 1UBYA 2OPNA 3ICNA 3N5HF 4GP1A 5IL3A 5A0KA 3Q1OA 3KRFB 1KIYA 3PH7A 4LFGA 3VJAA 3OACB 4NKFA 1JFGA 3WEKA 3CC9A 4LUUA 5A0JA 2J1PA 3SDUA 2AETA 3LDWA 2EWGA 4JVJF 4DWBA 1V4JA 4MC3A 4OMGA 5IK0A 2ZCRA 3WCFA 4KQ5A 4P0WA 2F9KF 3OABA 3G4DA 4LPHF 3BNYA 4KUXA 2Z7IA 3SDRA 2F8CF 3KROB 1HX9A 3APZA 4KKMA 2AZJA 4KQUA 5DGMF 5JA0F 3ACXA 3WCDA 1DGPA 3WCGA 2E8UA 2E94A 4MC0A 3PYAA 4OKZA 3Q30A 1WL1A 3LVSA 2PS6A 3LG5A 5DGSF 4LZ0A 3WEHA 4UMJA 3EFQA 1JFAA 4MC8A 3TFPA 1VG4A 2Z4YA 3OABB 5AELA 4KWDA 2Z7HA 1YYTA 4LXWA 3LK5A 3V1VA 5EROA 5ERMA 3ZMBA 3M02A 3SDQA 1KIZA 2AZLA 4GA3A 3AQCB 3SDTA 5IMPA 3VJBA 2RAHA 3N3DA 3IBAA 3WE9A 4E9ZA 3WCLA 3DYFA 3N3LF 3RYWA 1V4IA 4H5CF 2I19A 3KRFA 3WC9A 2F94F 4NUAA 1EZFA 2E95A 3KRAA 3OACA 3WEFA 5AFXA 2Z4XA 4N9UA 2Z4ZA 4OKMA 5DJPF 2F7MF 4KVDA 3WCCA 2Q9ZA 5JV0F 2AEKA 5DGNF 5IK6A 4H5EF 5ILDA 3KRCA 4LZCA 4ZQ8A 4QPFA 3LOMA 4LOBA 1HXGA 1YQ7A 3RMGA 1WMWA 4KQSA 1WL0A 3KROA 3MAVA 4KFAA 3KRAB 5B00A 3NRIA 3KBKA 4KVYA 3TFNA 1VG7A 2E4OA 2H8OA 3ZL6A 3LGKA 1FPSA 5EATA 3M01A 2E93A 4Q23A 1YV5A 1N20A 3CP6A 4F62A 3P5PA 3WCAA 2E8TA 5HN7A 5IKHA 1WL3A 3KRCB 2OA6A 2PS7A 4DHDA 3AQ0A 2ONGA 5I1UA 3B7LA 3G4FA 5E8HA 4LA5A 4JXYA 2F92F 3IPIA 3P5RA 4JZXA 4NFIF 4DI5A 3QQVA 4LLSA 3WSBA 5EAUA 3WCJA 3WCMA 1WY0A 2F8ZF 2Z52A 5ILYA 3M0GA 1RTRA 2PS4A 3Q2QA 3TFVA 4DXJA 4LFEA 1RQIA 3PKOA 3AE0A 5E8LA 2OGDA 4E9UA 1RQJA 3EGTA 3DYGA 3WCEA 1DI1A 3W7FA 5IM1A 4RNQA 5ILJA 4JXNA 4RXCA 3N0GA 5IK9A 4FP4A 3N1VF 1ZW5A 4GP2A 2Q58A 4QXSF 2VF6A 5IL8A 3WEJA 5C05A 1V4KA 2AZKA 2QISA 3KRPA 2DH4A 1HM7A 3CKEA 3NF2A 2E8WA 4LPGF 5B0IA 3ZMCA 5B0MA 1YYRA 2ONHA 2Z78A 3BNXA 3NPKA 4XQRF 4KPJA 3WEIA 1YYSA 2P1CA 3WEGA 1N22A 4DEMF 3ZOUA 2E8VA 3ICMA 4N1ZF 5JV1F 2Z50A 2ZCOA 5DIQF 3VJDA 3MZVA 1N21A 2E91A 4P0XA 3TC1A 1V4HA 4RXDA 4JZBA 3ACYA 4DWGA 5B0KA 3PYBA 1HM4A 1V4EA 3LZ9A 4P0VA 2ZEUA 3KRPB 3QKCA 5ER8A 4NG6A 4OMHA 3SAEA 4LZ3A 1YYUA 2E8XA 2J1OA 4KPDA 4XQSF 2E92A 5DZ2A 1N1ZA 2J5CA 3RYEA 4EA2A 1UBXA 3DYHA 2F89F 5ILKA 2E90A 5AHUB 4F6XA 5E8KA 2ZCQA 3LSNA 3ACWA 3LMDA 1UBWA 2Q9YA 5ILZA 4XQTF 4GAXA 4EA1A 5ILHA 3WJOA 2Z4WA 5CG6A 4RYPA 2Z4VA 3LGZB 1YHKA 1VG3A 3TS7A 2FTZA 1N1BA 2PS8A 5H9DA 2AELA 3VJ8A 2FORA 3P8RA 3S9VA 3N0FA 3LLWA 3ZCDA 3N1WF 1HXCA 5B01A 1PS1A 5IMIA 3WCIA 5JV2F 5HN9A 4F6VA 4NFKF 4LTZA 1YHMA 4L2XF 5DHIA 1YHLA 4LFVF 4FJQA 3Q2ZA 3P8LA 3ICKA 2O1OA 4NFJF 3V66A 4KVWA 3S4JA 3UCAA 4E1EA 5AYPA 3WJNA 3VJ9A 4PVYF 2ZEVA 3N45F 1HXAA 3P41A 1YJ4A 1VG2A 5B02A 3WJKA 1VG6A 5A0IA 5IMNA 3LEEA 3WCHA 3M9UA 5B0LA 5DJVF 2Q80A 3ASXA 5HN8A 3VJEA 4DZWA 4WK5A 5IN8A 5CG5A 5HNAA 4LIXA 3OYRA 4RXEA 3ADZA 3VJCA 1UBVA 4OGUA 4HD1A 3WSAA 5DJRF 3V1XA 4LA6A 5IKAA 1YYQA 3ICZA 4K10A 3ID0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PDE A;  2ZCS A;  5ERN A;  5B0J A;  3EZ3 A;  5B03 A;  5JUZ F;  5ILI A;  2ZY1 A;  1N23 A;  2OPM A;  1N24 A;  4KVI A;  5EAS A;  4LTV A;  3N46 F;  2PS5 A;  4LLT A;  3N6K F;  3SDV A;  3AQB B;  4JYX A;  4KK2 A;  3NPR A;  3N49 F;  3M00 A;  1WL2 A;  4H5D F;  3LJI A;  5DW7 A;  3KB9 A;  5DHK A;  3WCB A;  4NKE A;  4RXA A;  3N5J F;  5IVG A;  3RBM A;  5KSX F;  1WKZ A;  4PVX F;  4EA0 A;  1UBY A;  2OPN A;  3ICN A;  3N5H F;  4GP1 A;  5IL3 A;  5A0K A;  3Q1O A;  3KRF B;  1KIY A;  3PH7 A;  4LFG A;  3VJA A;  3OAC B;  4NKF A;  1JFG A;  3WEK A;  3CC9 A;  4LUU A;  5A0J A;  2J1P A;  3SDU A;  2AET A;  3LDW A;  2EWG A;  4JVJ F;  4DWB A;  1V4J A;  4MC3 A;  4OMG A;  5IK0 A;  2ZCR A;  3WCF A;  4KQ5 A;  4P0W A;  2F9K F;  3OAB A;  3G4D A;  4LPH F;  3BNY A;  4KUX A;  2Z7I A;  3SDR A;  2F8C F;  3KRO B;  1HX9 A;  3APZ A;  4KKM A;  2AZJ A;  4KQU A;  5DGM F;  5JA0 F;  3ACX A;  3WCD A;  1DGP A;  3WCG A;  2E8U A;  2E94 A;  4MC0 A;  3PYA A;  4OKZ A;  3Q30 A;  1WL1 A;  3LVS A;  2PS6 A;  3LG5 A;  5DGS F;  4LZ0 A;  3WEH A;  4UMJ A;  3EFQ A;  1JFA A;  4MC8 A;  3TFP A;  1VG4 A;  2Z4Y A;  3OAB B;  5AEL A;  4KWD A;  2Z7H A;  1YYT A;  4LXW A;  3LK5 A;  3V1V A;  5ERO A;  5ERM A;  3ZMB A;  3M02 A;  3SDQ A;  1KIZ A;  2AZL A;  4GA3 A;  3AQC B;  3SDT A;  5IMP A;  3VJB A;  2RAH A;  3N3D A;  3IBA A;  3WE9 A;  4E9Z A;  3WCL A;  3DYF A;  3N3L F;  3RYW A;  1V4I A;  4H5C F;  2I19 A;  3KRF A;  3WC9 A;  2F94 F;  4NUA A;  1EZF A;  2E95 A;  3KRA A;  3OAC A;  3WEF A;  5AFX A;  2Z4X A;  4N9U A;  2Z4Z A;  4OKM A;  5DJP F;  2F7M F;  4KVD A;  3WCC A;  2Q9Z A;  5JV0 F;  2AEK A;  5DGN F;  5IK6 A;  4H5E F;  5ILD A;  3KRC A;  4LZC A;  4ZQ8 A;  4QPF A;  3LOM A;  4LOB A;  1HXG A;  1YQ7 A;  3RMG A;  1WMW A;  4KQS A;  1WL0 A;  3KRO A;  3MAV A;  4KFA A;  3KRA B;  5B00 A;  3NRI A;  3KBK A;  4KVY A;  3TFN A;  1VG7 A;  2E4O A;  2H8O A;  3ZL6 A;  3LGK A;  1FPS A;  5EAT A;  3M01 A;  2E93 A;  4Q23 A;  1YV5 A;  1N20 A;  3CP6 A;  4F62 A;  3P5P A;  3WCA A;  2E8T A;  5HN7 A;  5IKH A;  1WL3 A;  3KRC B;  2OA6 A;  2PS7 A;  4DHD A;  3AQ0 A;  2ONG A;  5I1U A;  3B7L A;  3G4F A;  5E8H A;  4LA5 A;  4JXY A;  2F92 F;  3IPI A;  3P5R A;  4JZX A;  4NFI F;  4DI5 A;  3QQV A;  4LLS A;  3WSB A;  5EAU A;  3WCJ A;  3WCM A;  1WY0 A;  2F8Z F;  2Z52 A;  5ILY A;  3M0G A;  1RTR A;  2PS4 A;  3Q2Q A;  3TFV A;  4DXJ A;  4LFE A;  1RQI A;  3PKO A;  3AE0 A;  5E8L A;  2OGD A;  4E9U A;  1RQJ A;  3EGT A;  3DYG A;  3WCE A;  1DI1 A;  3W7F A;  5IM1 A;  4RNQ A;  5ILJ A;  4JXN A;  4RXC A;  3N0G A;  5IK9 A;  4FP4 A;  3N1V F;  1ZW5 A;  4GP2 A;  2Q58 A;  4QXS F;  2VF6 A;  5IL8 A;  3WEJ A;  5C05 A;  1V4K A;  2AZK A;  2QIS A;  3KRP A;  2DH4 A;  1HM7 A;  3CKE A;  3NF2 A;  2E8W A;  4LPG F;  5B0I A;  3ZMC A;  5B0M A;  1YYR A;  2ONH A;  2Z78 A;  3BNX A;  3NPK A;  4XQR F;  4KPJ A;  3WEI A;  1YYS A;  2P1C A;  3WEG A;  1N22 A;  4DEM F;  3ZOU A;  2E8V A;  3ICM A;  4N1Z F;  5JV1 F;  2Z50 A;  2ZCO A;  5DIQ F;  3VJD A;  3MZV A;  1N21 A;  2E91 A;  4P0X A;  3TC1 A;  1V4H A;  4RXD A;  4JZB A;  3ACY A;  4DWG A;  5B0K A;  3PYB A;  1HM4 A;  1V4E A;  3LZ9 A;  4P0V A;  2ZEU A;  3KRP B;  3QKC A;  5ER8 A;  4NG6 A;  4OMH A;  3SAE A;  4LZ3 A;  1YYU A;  2E8X A;  2J1O A;  4KPD A;  4XQS F;  2E92 A;  5DZ2 A;  1N1Z A;  2J5C A;  3RYE A;  4EA2 A;  1UBX A;  3DYH A;  2F89 F;  5ILK A;  2E90 A;  5AHU B;  4F6X A;  5E8K A;  2ZCQ A;  3LSN A;  3ACW A;  3LMD A;  1UBW A;  2Q9Y A;  5ILZ A;  4XQT F;  4GAX A;  4EA1 A;  5ILH A;  3WJO A;  2Z4W A;  5CG6 A;  4RYP A;  2Z4V A;  3LGZ B;  1YHK A;  1VG3 A;  3TS7 A;  2FTZ A;  1N1B A;  2PS8 A;  5H9D A;  2AEL A;  3VJ8 A;  2FOR A;  3P8R A;  3S9V A;  3N0F A;  3LLW A;  3ZCD A;  3N1W F;  1HXC A;  5B01 A;  1PS1 A;  5IMI A;  3WCI A;  5JV2 F;  5HN9 A;  4F6V A;  4NFK F;  4LTZ A;  1YHM A;  4L2X F;  5DHI A;  1YHL A;  4LFV F;  4FJQ A;  3Q2Z A;  3P8L A;  3ICK A;  2O1O A;  4NFJ F;  3V66 A;  4KVW A;  3S4J A;  3UCA A;  4E1E A;  5AYP A;  3WJN A;  3VJ9 A;  4PVY F;  2ZEV A;  3N45 F;  1HXA A;  3P41 A;  1YJ4 A;  1VG2 A;  5B02 A;  3WJK A;  1VG6 A;  5A0I A;  5IMN A;  3LEE A;  3WCH A;  3M9U A;  5B0L A;  5DJV F;  2Q80 A;  3ASX A;  5HN8 A;  3VJE A;  4DZW A;  4WK5 A;  5IN8 A;  5CG5 A;  5HNA A;  4LIX A;  3OYR A;  4RXE A;  3ADZ A;  3VJC A;  1UBV A;  4OGU A;  4HD1 A;  3WSA A;  5DJR F;  3V1X A;  4LA6 A;  5IKA A;  1YYQ A;  3ICZ A;  4K10 A;  3ID0 A; 
#chains in the Genus database with same CATH topology
 3PDE A;  2ZCS A;  5ERN A;  5B0J A;  3EZ3 A;  5B03 A;  5JUZ F;  5ILI A;  2ZY1 A;  1N23 A;  2OPM A;  1N24 A;  4KVI A;  5EAS A;  4LTV A;  3N46 F;  2PS5 A;  4LLT A;  3N6K F;  3SDV A;  3AQB B;  4JYX A;  4KK2 A;  3NPR A;  3N49 F;  3M00 A;  1WL2 A;  4H5D F;  3LJI A;  5DW7 A;  3KB9 A;  5DHK A;  3WCB A;  4NKE A;  4RXA A;  3N5J F;  5IVG A;  3RBM A;  5KSX F;  1WKZ A;  4PVX F;  4EA0 A;  1UBY A;  2OPN A;  3ICN A;  3N5H F;  4GP1 A;  5IL3 A;  5A0K A;  3Q1O A;  3KRF B;  1KIY A;  3PH7 A;  4LFG A;  3VJA A;  3OAC B;  4NKF A;  1JFG A;  3WEK A;  3CC9 A;  4LUU A;  5A0J A;  2J1P A;  3SDU A;  2AET A;  3LDW A;  2EWG A;  4JVJ F;  4DWB A;  1V4J A;  4MC3 A;  4OMG A;  5IK0 A;  2ZCR A;  3WCF A;  4KQ5 A;  4P0W A;  2F9K F;  3OAB A;  3G4D A;  4LPH F;  3BNY A;  4KUX A;  2Z7I A;  3SDR A;  2F8C F;  3KRO B;  1HX9 A;  3APZ A;  4KKM A;  2AZJ A;  4KQU A;  5DGM F;  5JA0 F;  3ACX A;  3WCD A;  1DGP A;  3WCG A;  2E8U A;  2E94 A;  4MC0 A;  3PYA A;  4OKZ A;  3Q30 A;  1WL1 A;  3LVS A;  2PS6 A;  3LG5 A;  5DGS F;  4LZ0 A;  3WEH A;  4UMJ A;  3EFQ A;  1JFA A;  4MC8 A;  3TFP A;  1VG4 A;  2Z4Y A;  3OAB B;  5AEL A;  4KWD A;  2Z7H A;  1YYT A;  4LXW A;  3LK5 A;  3V1V A;  5ERO A;  5ERM A;  3ZMB A;  3M02 A;  3SDQ A;  1KIZ A;  2AZL A;  4GA3 A;  3AQC B;  3SDT A;  5IMP A;  3VJB A;  2RAH A;  3N3D A;  3IBA A;  3WE9 A;  4E9Z A;  3WCL A;  3DYF A;  3N3L F;  3RYW A;  1V4I A;  4H5C F;  2I19 A;  3KRF A;  3WC9 A;  2F94 F;  4NUA A;  1EZF A;  2E95 A;  3KRA A;  3OAC A;  3WEF A;  5AFX A;  2Z4X A;  4N9U A;  2Z4Z A;  4OKM A;  5DJP F;  2F7M F;  4KVD A;  3WCC A;  2Q9Z A;  5JV0 F;  2AEK A;  5DGN F;  5IK6 A;  4H5E F;  5ILD A;  3KRC A;  4LZC A;  4ZQ8 A;  4QPF A;  3LOM A;  4LOB A;  1HXG A;  1YQ7 A;  3RMG A;  1WMW A;  4KQS A;  1WL0 A;  3KRO A;  3MAV A;  4KFA A;  3KRA B;  5B00 A;  3NRI A;  3KBK A;  4KVY A;  3TFN A;  1VG7 A;  2E4O A;  2H8O A;  3ZL6 A;  3LGK A;  1FPS A;  5EAT A;  3M01 A;  2E93 A;  4Q23 A;  1YV5 A;  1N20 A;  3CP6 A;  4F62 A;  3P5P A;  3WCA A;  2E8T A;  5HN7 A;  5IKH A;  1WL3 A;  3KRC B;  2OA6 A;  2PS7 A;  4DHD A;  3AQ0 A;  2ONG A;  5I1U A;  3B7L A;  3G4F A;  5E8H A;  4LA5 A;  4JXY A;  2F92 F;  3IPI A;  3P5R A;  4JZX A;  4NFI F;  4DI5 A;  3QQV A;  4LLS A;  3WSB A;  5EAU A;  3WCJ A;  3WCM A;  1WY0 A;  2F8Z F;  2Z52 A;  5ILY A;  3M0G A;  1RTR A;  2PS4 A;  3Q2Q A;  3TFV A;  4DXJ A;  4LFE A;  1RQI A;  3PKO A;  3AE0 A;  5E8L A;  2OGD A;  4E9U A;  1RQJ A;  3EGT A;  3DYG A;  3WCE A;  1DI1 A;  3W7F A;  5IM1 A;  4RNQ A;  5ILJ A;  4JXN A;  4RXC A;  3N0G A;  5IK9 A;  4FP4 A;  3N1V F;  1ZW5 A;  4GP2 A;  2Q58 A;  4QXS F;  2VF6 A;  5IL8 A;  3WEJ A;  5C05 A;  1V4K A;  2AZK A;  2QIS A;  3KRP A;  2DH4 A;  1HM7 A;  3CKE A;  3NF2 A;  2E8W A;  4LPG F;  5B0I A;  3ZMC A;  5B0M A;  1YYR A;  2ONH A;  2Z78 A;  3BNX A;  3NPK A;  4XQR F;  4KPJ A;  3WEI A;  1YYS A;  2P1C A;  3WEG A;  1N22 A;  4DEM F;  3ZOU A;  2E8V A;  3ICM A;  4N1Z F;  5JV1 F;  2Z50 A;  2ZCO A;  5DIQ F;  3VJD A;  3MZV A;  1N21 A;  2E91 A;  4P0X A;  3TC1 A;  1V4H A;  4RXD A;  4JZB A;  3ACY A;  4DWG A;  5B0K A;  3PYB A;  1HM4 A;  1V4E A;  3LZ9 A;  4P0V A;  2ZEU A;  3KRP B;  3QKC A;  5ER8 A;  4NG6 A;  4OMH A;  3SAE A;  4LZ3 A;  1YYU A;  2E8X A;  2J1O A;  4KPD A;  4XQS F;  2E92 A;  5DZ2 A;  1N1Z A;  2J5C A;  3RYE A;  4EA2 A;  1UBX A;  3DYH A;  2F89 F;  5ILK A;  2E90 A;  5AHU B;  4F6X A;  5E8K A;  2ZCQ A;  3LSN A;  3ACW A;  3LMD A;  1UBW A;  2Q9Y A;  5ILZ A;  4XQT F;  4GAX A;  4EA1 A;  5ILH A;  3WJO A;  2Z4W A;  5CG6 A;  4RYP A;  2Z4V A;  3LGZ B;  1YHK A;  1VG3 A;  3TS7 A;  2FTZ A;  1N1B A;  2PS8 A;  5H9D A;  2AEL A;  3VJ8 A;  2FOR A;  3P8R A;  3S9V A;  3N0F A;  3LLW A;  3ZCD A;  3N1W F;  1HXC A;  5B01 A;  1PS1 A;  5IMI A;  3WCI A;  5JV2 F;  5HN9 A;  4F6V A;  4NFK F;  4LTZ A;  1YHM A;  4L2X F;  5DHI A;  1YHL A;  4LFV F;  4FJQ A;  3Q2Z A;  3P8L A;  3ICK A;  2O1O A;  4NFJ F;  3V66 A;  4KVW A;  3S4J A;  3UCA A;  4E1E A;  5AYP A;  3WJN A;  3VJ9 A;  4PVY F;  2ZEV A;  3N45 F;  1HXA A;  3P41 A;  1YJ4 A;  1VG2 A;  5B02 A;  3WJK A;  1VG6 A;  5A0I A;  5IMN A;  3LEE A;  3WCH A;  3M9U A;  5B0L A;  5DJV F;  2Q80 A;  3ASX A;  5HN8 A;  3VJE A;  4DZW A;  4WK5 A;  5IN8 A;  5CG5 A;  5HNA A;  4LIX A;  3OYR A;  4RXE A;  3ADZ A;  3VJC A;  1UBV A;  4OGU A;  4HD1 A;  3WSA A;  5DJR F;  3V1X A;  4LA6 A;  5IKA A;  1YYQ A;  3ICZ A;  4K10 A;  3ID0 A; 
#chains in the Genus database with same CATH homology
 3PDE A;  2ZCS A;  5ERN A;  5B0J A;  3EZ3 A;  5B03 A;  5JUZ F;  5ILI A;  2ZY1 A;  1N23 A;  2OPM A;  1N24 A;  4KVI A;  5EAS A;  4LTV A;  3N46 F;  2PS5 A;  4LLT A;  3N6K F;  3SDV A;  3AQB B;  4JYX A;  4KK2 A;  3NPR A;  3N49 F;  3M00 A;  1WL2 A;  4H5D F;  3LJI A;  5DW7 A;  3KB9 A;  5DHK A;  3WCB A;  4NKE A;  4RXA A;  3N5J F;  5IVG A;  3RBM A;  5KSX F;  1WKZ A;  4PVX F;  4EA0 A;  1UBY A;  2OPN A;  3ICN A;  3N5H F;  4GP1 A;  5IL3 A;  5A0K A;  3Q1O A;  3KRF B;  1KIY A;  3PH7 A;  4LFG A;  3VJA A;  3OAC B;  4NKF A;  1JFG A;  3WEK A;  3CC9 A;  4LUU A;  5A0J A;  2J1P A;  3SDU A;  2AET A;  3LDW A;  2EWG A;  4JVJ F;  4DWB A;  1V4J A;  4MC3 A;  4OMG A;  5IK0 A;  2ZCR A;  3WCF A;  4KQ5 A;  4P0W A;  2F9K F;  3OAB A;  3G4D A;  4LPH F;  3BNY A;  4KUX A;  2Z7I A;  3SDR A;  2F8C F;  3KRO B;  1HX9 A;  3APZ A;  4KKM A;  2AZJ A;  4KQU A;  5DGM F;  5JA0 F;  3ACX A;  3WCD A;  1DGP A;  3WCG A;  2E8U A;  2E94 A;  4MC0 A;  3PYA A;  4OKZ A;  3Q30 A;  1WL1 A;  3LVS A;  2PS6 A;  3LG5 A;  5DGS F;  4LZ0 A;  3WEH A;  4UMJ A;  3EFQ A;  1JFA A;  4MC8 A;  3TFP A;  1VG4 A;  2Z4Y A;  3OAB B;  5AEL A;  4KWD A;  2Z7H A;  1YYT A;  4LXW A;  3LK5 A;  3V1V A;  5ERO A;  5ERM A;  3ZMB A;  3M02 A;  3SDQ A;  1KIZ A;  2AZL A;  4GA3 A;  3AQC B;  3SDT A;  5IMP A;  3VJB A;  2RAH A;  3N3D A;  3IBA A;  3WE9 A;  4E9Z A;  3WCL A;  3DYF A;  3N3L F;  3RYW A;  1V4I A;  4H5C F;  2I19 A;  3KRF A;  3WC9 A;  2F94 F;  4NUA A;  1EZF A;  2E95 A;  3KRA A;  3OAC A;  3WEF A;  5AFX A;  2Z4X A;  4N9U A;  2Z4Z A;  4OKM A;  5DJP F;  2F7M F;  4KVD A;  3WCC A;  2Q9Z A;  5JV0 F;  2AEK A;  5DGN F;  5IK6 A;  4H5E F;  5ILD A;  3KRC A;  4LZC A;  4ZQ8 A;  4QPF A;  3LOM A;  4LOB A;  1HXG A;  1YQ7 A;  3RMG A;  1WMW A;  4KQS A;  1WL0 A;  3KRO A;  3MAV A;  4KFA A;  3KRA B;  5B00 A;  3NRI A;  3KBK A;  4KVY A;  3TFN A;  1VG7 A;  2E4O A;  2H8O A;  3ZL6 A;  3LGK A;  1FPS A;  5EAT A;  3M01 A;  2E93 A;  4Q23 A;  1YV5 A;  1N20 A;  3CP6 A;  4F62 A;  3P5P A;  3WCA A;  2E8T A;  5HN7 A;  5IKH A;  1WL3 A;  3KRC B;  2OA6 A;  2PS7 A;  4DHD A;  3AQ0 A;  2ONG A;  5I1U A;  3B7L A;  3G4F A;  5E8H A;  4LA5 A;  4JXY A;  2F92 F;  3IPI A;  3P5R A;  4JZX A;  4NFI F;  4DI5 A;  3QQV A;  4LLS A;  3WSB A;  5EAU A;  3WCJ A;  3WCM A;  1WY0 A;  2F8Z F;  2Z52 A;  5ILY A;  3M0G A;  1RTR A;  2PS4 A;  3Q2Q A;  3TFV A;  4DXJ A;  4LFE A;  1RQI A;  3PKO A;  3AE0 A;  5E8L A;  2OGD A;  4E9U A;  1RQJ A;  3EGT A;  3DYG A;  3WCE A;  1DI1 A;  3W7F A;  5IM1 A;  4RNQ A;  5ILJ A;  4JXN A;  4RXC A;  3N0G A;  5IK9 A;  4FP4 A;  3N1V F;  1ZW5 A;  4GP2 A;  2Q58 A;  4QXS F;  2VF6 A;  5IL8 A;  3WEJ A;  5C05 A;  1V4K A;  2AZK A;  2QIS A;  3KRP A;  2DH4 A;  1HM7 A;  3CKE A;  3NF2 A;  2E8W A;  4LPG F;  5B0I A;  3ZMC A;  5B0M A;  1YYR A;  2ONH A;  2Z78 A;  3BNX A;  3NPK A;  4XQR F;  4KPJ A;  3WEI A;  1YYS A;  2P1C A;  3WEG A;  1N22 A;  4DEM F;  3ZOU A;  2E8V A;  3ICM A;  4N1Z F;  5JV1 F;  2Z50 A;  2ZCO A;  5DIQ F;  3VJD A;  3MZV A;  1N21 A;  2E91 A;  4P0X A;  3TC1 A;  1V4H A;  4RXD A;  4JZB A;  3ACY A;  4DWG A;  5B0K A;  3PYB A;  1HM4 A;  1V4E A;  3LZ9 A;  4P0V A;  2ZEU A;  3KRP B;  3QKC A;  5ER8 A;  4NG6 A;  4OMH A;  3SAE A;  4LZ3 A;  1YYU A;  2E8X A;  2J1O A;  4KPD A;  4XQS F;  2E92 A;  5DZ2 A;  1N1Z A;  2J5C A;  3RYE A;  4EA2 A;  1UBX A;  3DYH A;  2F89 F;  5ILK A;  2E90 A;  5AHU B;  4F6X A;  5E8K A;  2ZCQ A;  3LSN A;  3ACW A;  3LMD A;  1UBW A;  2Q9Y A;  5ILZ A;  4XQT F;  4GAX A;  4EA1 A;  5ILH A;  3WJO A;  2Z4W A;  5CG6 A;  4RYP A;  2Z4V A;  3LGZ B;  1YHK A;  1VG3 A;  3TS7 A;  2FTZ A;  1N1B A;  2PS8 A;  5H9D A;  2AEL A;  3VJ8 A;  2FOR A;  3P8R A;  3S9V A;  3N0F A;  3LLW A;  3ZCD A;  3N1W F;  1HXC A;  5B01 A;  1PS1 A;  5IMI A;  3WCI A;  5JV2 F;  5HN9 A;  4F6V A;  4NFK F;  4LTZ A;  1YHM A;  4L2X F;  5DHI A;  1YHL A;  4LFV F;  4FJQ A;  3Q2Z A;  3P8L A;  3ICK A;  2O1O A;  4NFJ F;  3V66 A;  4KVW A;  3S4J A;  3UCA A;  4E1E A;  5AYP A;  3WJN A;  3VJ9 A;  4PVY F;  2ZEV A;  3N45 F;  1HXA A;  3P41 A;  1YJ4 A;  1VG2 A;  5B02 A;  3WJK A;  1VG6 A;  5A0I A;  5IMN A;  3LEE A;  3WCH A;  3M9U A;  5B0L A;  5DJV F;  2Q80 A;  3ASX A;  5HN8 A;  3VJE A;  4DZW A;  4WK5 A;  5IN8 A;  5CG5 A;  5HNA A;  4LIX A;  3OYR A;  4RXE A;  3ADZ A;  3VJC A;  1UBV A;  4OGU A;  4HD1 A;  3WSA A;  5DJR F;  3V1X A;  4LA6 A;  5IKA A;  1YYQ A;  3ICZ A;  4K10 A;  3ID0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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