5DGNF

Crystal structure of human fpps in complex with compound 13
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
343
structure length
343
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords Farnesyl pyrophosphate synthase
publication title Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.
pubmed doi rcsb
source organism Homo sapiens
total genus 132
structure length 343
sequence length 343
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2015-08-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 5dgnF00
4JVJF 5DJPF 1WL3A 3KRPB 5DJRF 3SDTA 3KRFA 5DIQF 2F7MF 4RXDA 4LLSA 5IN8A 5AHUB 3KRCB 1WMWA 5JV1F 1RQIA 3W7FA 5IMIA 1HM4A 3PH7A 4LFVF 1HXCA 2F94F 3ZCDA 5HNAA 3ACWA 4N1ZF 3ICNA 4NFKF 4RXAA 4DWGA 5HN7A 3LOMA 5B0LA 5EROA 5IK6A 2ZEUA 3LLWA 5B00A 1KIYA 4NKEA 2AETA 5DHKA 3N49F 5B0MA 3ICZA 3CKEA 5EATA 4KPJA 4KVWA 3WCGA 3M9UA 5AYPA 5AELA 3ADZA 4OMGA 3VJEA 5CG5A 3LEEA 2AELA 2Q9ZA 2Q58A 3RYWA 5DJVF 5ILYA 5AFXA 4FP4A 3ICKA 4DZWA 1YYRA 3KRPA 4EA0A 2ONHA 5ILZA 3WCJA 2E8VA 3ACXA 3WC9A 2E94A 2PS8A 2J1OA 4DXJA 4UMJA 5B01A 4RYPA 3KROB 3MZVA 3VJ9A 3WE9A 3WCHA 3VJDA 1VG2A 4JXNA 4KWDA 4NUAA 2P1CA 4JZBA 2E4OA 3SDRA 4LPHF 3KRFB 4H5DF 5IKAA 1YYSA 3VJ8A 2VF6A 3WJOA 5ILKA 3S9VA 3ZMBA 3MAVA 3KRAA 3SDVA 3LDWA 1UBXA 4L2XF 3OACB 2AZLA 1YHLA 3ZMCA 5EASA 3VJBA 3WEHA 3DYGA 2E8XA 1YYUA 3B7LA 4EA1A 5E8HA 3V66A 4E1EA 3WCAA 5B03A 3WCIA 2PS5A 5ERNA 4K10A 4ZQ8A 4N9UA 1JFAA 2OPNA 5JV0F 1VG4A 3KROA 3IBAA 4LZCA 4LFGA 4GP1A 3WEKA 5ILJA 4NFIF 3NPRA 3BNXA 4GP2A 1UBYA 3QQVA 1YHMA 3M01A 3G4DA 2E8WA 5DHIA 1WY0A 3N45F 3P8LA 4F62A 2FORA 1WL1A 4Q23A 4KPDA 5ERMA 2RAHA 4LA6A 3TC1A 3RMGA 1JFGA 1DGPA 3LZ9A 3OACA 2Z4XA 3PYAA 2J5CA 2ZY1A 2ONGA 3QKCA 5IMPA 2AZJA 3KRAB 4RXEA 2ZCQA 2Z4ZA 1HXGA 3VJCA 3LGZB 4MC8A 4DHDA 3NPKA 5CG6A 1N20A 5ILDA 1N22A 2QISA 3WEFA 2Q9YA 4JXYA 4RXCA 5IK0A 1FPSA 4KVDA 4KK2A 1VG3A 4DEMF 4KQUA 3IPIA 4LOBA 5E8KA 3AQ0A 3TFNA 1HX9A 2J1PA 3N3DA 3EZ3A 1N1BA 3M0GA 1V4HA 4LFEA 2Z52A 2F9KF 4LZ3A 3N5JF 4H5EF 5C05A 3NF2A 3ICMA 3LG5A 3ZOUA 4LTZA 3WEGA 1RQJA 4MC3A 2E90A 2PS4A 3WEJA 1YYQA 3N46F 4EA2A 3TFVA 4FJQA 3WJNA 2OPMA 3PYBA 5A0JA 3SDQA 3WJKA 3WSAA 3PKOA 3PDEA 3SAEA 4LA5A 4LXWA 5JA0F 3ZL6A 4PVXF 3ASXA 3P8RA 4JYXA 3WCDA 3AQBB 4GAXA 1N1ZA 4QPFA 1VG7A 1V4JA 2ZEVA 5DGMF 5I1UA 2E91A 2Z50A 1UBVA 2EWGA 4LZ0A 5KSXF 3Q1OA 2ZCRA 1YJ4A 2DH4A 5IVGA 3WCFA 3M00A 5IKHA 5H9DA 5IL8A 2OA6A 3ACYA 1UBWA 1HM7A 3NRIA 3LGKA 4XQTF 5JV2F 4H5CF 1WKZA 4LPGF 3LK5A 4OKMA 1DI1A 4NFJF 5B02A 2Z7IA 1EZFA 5IMNA 5DGSF 3RYEA 3OABA 2I19A 5DW7A 4XQSF 4OMHA 3KBKA 3P5RA 1ZW5A 1YHKA 4JZXA 4KUXA 3RBMA 1V4EA 4KQSA 3N3LF 4KVYA 2E95A 4OGUA 2E92A 3WCLA 2F92F 5E8LA 3P41A 4KKMA 3CP6A 1YQ7A 5IM1A 2PS6A 5DGNF 3UCAA 4DI5A 4OKZA 4RNQA 3OYRA 2AZKA 3WSBA 4E9ZA 3Q2ZA 3LSNA 4LLTA 3LMDA 3WCBA 4DWBA 4HD1A 3N0FA 2FTZA 1KIZA 1HXAA 4P0VA 2Z4YA 3KB9A 5ER8A 4GA3A 3WCCA 3TS7A 1V4KA 3APZA 3WCEA 1RTRA 3LVSA 5IK9A 3V1XA 2E93A 2E8UA 2Q80A 3N5HF 5B0JA 3DYFA 3TFPA 1N21A 2F89F 3WCMA 1YYTA 4PVYF 4KQ5A 3SDUA 2F8CF 5EAUA 3Q30A 3OABB 2H8OA 5DZ2A 3G4FA 4NG6A 2ZCSA 5B0IA 5ILIA 4E9UA 4MC0A 5JUZF 2PS7A 4F6VA 4QXSF 3KRCA 5HN8A 2AEKA 1V4IA 4WK5A 5A0KA 3N1WF 4LUUA 3AQCB 1YV5A 3N1VF 1WL2A 2Z7HA 4NKFA 3S4JA 2Z4VA 3AE0A 3Q2QA 4P0XA 1PS1A 3DYHA 4KFAA 5IL3A 3N6KF 2Z78A 4LTVA 3BNYA 2O1OA 3CC9A 3N0GA 4LIXA 3VJAA 3WEIA 2F8ZF 5HN9A 2OGDA 4P0WA 5ILHA 4KVIA 1N24A 3V1VA 3EFQA 4XQRF 4F6XA 1WL0A 5A0IA 2Z4WA 5B0KA 3EGTA 2E8TA 2ZCOA 3P5PA 1N23A 3ID0A 1VG6A 3M02A 3LJIA
chains in the Genus database with same CATH superfamily
4JVJF 5DJPF 1WL3A 3KRPB 5DJRF 3SDTA 3KRFA 5DIQF 2F7MF 4RXDA 4LLSA 5IN8A 5AHUB 3KRCB 1WMWA 5JV1F 1RQIA 3W7FA 5IMIA 1HM4A 3PH7A 4LFVF 1HXCA 2F94F 3ZCDA 5HNAA 3ACWA 4N1ZF 3ICNA 4NFKF 4RXAA 4DWGA 5HN7A 3LOMA 5B0LA 5EROA 5IK6A 2ZEUA 3LLWA 5B00A 1KIYA 4NKEA 2AETA 5DHKA 3N49F 5B0MA 3ICZA 3CKEA 5EATA 4KPJA 4KVWA 3WCGA 3M9UA 5AYPA 5AELA 3ADZA 4OMGA 3VJEA 5CG5A 3LEEA 2AELA 2Q9ZA 2Q58A 3RYWA 5DJVF 5ILYA 5AFXA 4FP4A 3ICKA 4DZWA 1YYRA 3KRPA 4EA0A 2ONHA 5ILZA 3WCJA 2E8VA 3ACXA 3WC9A 2E94A 2PS8A 2J1OA 4DXJA 4UMJA 5B01A 4RYPA 3KROB 3MZVA 3VJ9A 3WE9A 3WCHA 3VJDA 1VG2A 4JXNA 4KWDA 4NUAA 2P1CA 4JZBA 2E4OA 3SDRA 4LPHF 3KRFB 4H5DF 5IKAA 1YYSA 3VJ8A 2VF6A 3WJOA 5ILKA 3S9VA 3ZMBA 3MAVA 3KRAA 3SDVA 3LDWA 1UBXA 4L2XF 3OACB 2AZLA 1YHLA 3ZMCA 5EASA 3VJBA 3WEHA 3DYGA 2E8XA 1YYUA 3B7LA 4EA1A 5E8HA 3V66A 4E1EA 3WCAA 5B03A 3WCIA 2PS5A 5ERNA 4K10A 4ZQ8A 4N9UA 1JFAA 2OPNA 5JV0F 1VG4A 3KROA 3IBAA 4LZCA 4LFGA 4GP1A 3WEKA 5ILJA 4NFIF 3NPRA 3BNXA 4GP2A 1UBYA 3QQVA 1YHMA 3M01A 3G4DA 2E8WA 5DHIA 1WY0A 3N45F 3P8LA 4F62A 2FORA 1WL1A 4Q23A 4KPDA 5ERMA 2RAHA 4LA6A 3TC1A 3RMGA 1JFGA 1DGPA 3LZ9A 3OACA 2Z4XA 3PYAA 2J5CA 2ZY1A 2ONGA 3QKCA 5IMPA 2AZJA 3KRAB 4RXEA 2ZCQA 2Z4ZA 1HXGA 3VJCA 3LGZB 4MC8A 4DHDA 3NPKA 5CG6A 1N20A 5ILDA 1N22A 2QISA 3WEFA 2Q9YA 4JXYA 4RXCA 5IK0A 1FPSA 4KVDA 4KK2A 1VG3A 4DEMF 4KQUA 3IPIA 4LOBA 5E8KA 3AQ0A 3TFNA 1HX9A 2J1PA 3N3DA 3EZ3A 1N1BA 3M0GA 1V4HA 4LFEA 2Z52A 2F9KF 4LZ3A 3N5JF 4H5EF 5C05A 3NF2A 3ICMA 3LG5A 3ZOUA 4LTZA 3WEGA 1RQJA 4MC3A 2E90A 2PS4A 3WEJA 1YYQA 3N46F 4EA2A 3TFVA 4FJQA 3WJNA 2OPMA 3PYBA 5A0JA 3SDQA 3WJKA 3WSAA 3PKOA 3PDEA 3SAEA 4LA5A 4LXWA 5JA0F 3ZL6A 4PVXF 3ASXA 3P8RA 4JYXA 3WCDA 3AQBB 4GAXA 1N1ZA 4QPFA 1VG7A 1V4JA 2ZEVA 5DGMF 5I1UA 2E91A 2Z50A 1UBVA 2EWGA 4LZ0A 5KSXF 3Q1OA 2ZCRA 1YJ4A 2DH4A 5IVGA 3WCFA 3M00A 5IKHA 5H9DA 5IL8A 2OA6A 3ACYA 1UBWA 1HM7A 3NRIA 3LGKA 4XQTF 5JV2F 4H5CF 1WKZA 4LPGF 3LK5A 4OKMA 1DI1A 4NFJF 5B02A 2Z7IA 1EZFA 5IMNA 5DGSF 3RYEA 3OABA 2I19A 5DW7A 4XQSF 4OMHA 3KBKA 3P5RA 1ZW5A 1YHKA 4JZXA 4KUXA 3RBMA 1V4EA 4KQSA 3N3LF 4KVYA 2E95A 4OGUA 2E92A 3WCLA 2F92F 5E8LA 3P41A 4KKMA 3CP6A 1YQ7A 5IM1A 2PS6A 5DGNF 3UCAA 4DI5A 4OKZA 4RNQA 3OYRA 2AZKA 3WSBA 4E9ZA 3Q2ZA 3LSNA 4LLTA 3LMDA 3WCBA 4DWBA 4HD1A 3N0FA 2FTZA 1KIZA 1HXAA 4P0VA 2Z4YA 3KB9A 5ER8A 4GA3A 3WCCA 3TS7A 1V4KA 3APZA 3WCEA 1RTRA 3LVSA 5IK9A 3V1XA 2E93A 2E8UA 2Q80A 3N5HF 5B0JA 3DYFA 3TFPA 1N21A 2F89F 3WCMA 1YYTA 4PVYF 4KQ5A 3SDUA 2F8CF 5EAUA 3Q30A 3OABB 2H8OA 5DZ2A 3G4FA 4NG6A 2ZCSA 5B0IA 5ILIA 4E9UA 4MC0A 5JUZF 2PS7A 4F6VA 4QXSF 3KRCA 5HN8A 2AEKA 1V4IA 4WK5A 5A0KA 3N1WF 4LUUA 3AQCB 1YV5A 3N1VF 1WL2A 2Z7HA 4NKFA 3S4JA 2Z4VA 3AE0A 3Q2QA 4P0XA 1PS1A 3DYHA 4KFAA 5IL3A 3N6KF 2Z78A 4LTVA 3BNYA 2O1OA 3CC9A 3N0GA 4LIXA 3VJAA 3WEIA 2F8ZF 5HN9A 2OGDA 4P0WA 5ILHA 4KVIA 1N24A 3V1VA 3EFQA 4XQRF 4F6XA 1WL0A 5A0IA 2Z4WA 5B0KA 3EGTA 2E8TA 2ZCOA 3P5PA 1N23A 3ID0A 1VG6A 3M02A 3LJIA
chains in the Genus database with same CATH topology
4JVJF 5DJPF 1WL3A 3KRPB 5DJRF 3SDTA 3KRFA 5DIQF 2F7MF 4RXDA 4LLSA 5IN8A 5AHUB 3KRCB 1WMWA 5JV1F 1RQIA 3W7FA 5IMIA 1HM4A 3PH7A 4LFVF 1HXCA 2F94F 3ZCDA 5HNAA 3ACWA 4N1ZF 3ICNA 4NFKF 4RXAA 4DWGA 5HN7A 3LOMA 5B0LA 5EROA 5IK6A 2ZEUA 3LLWA 5B00A 1KIYA 4NKEA 2AETA 5DHKA 3N49F 5B0MA 3ICZA 3CKEA 5EATA 4KPJA 4KVWA 3WCGA 3M9UA 5AYPA 5AELA 3ADZA 4OMGA 3VJEA 5CG5A 3LEEA 2AELA 2Q9ZA 2Q58A 3RYWA 5DJVF 5ILYA 5AFXA 4FP4A 3ICKA 4DZWA 1YYRA 3KRPA 4EA0A 2ONHA 5ILZA 3WCJA 2E8VA 3ACXA 3WC9A 2E94A 2PS8A 2J1OA 4DXJA 4UMJA 5B01A 4RYPA 3KROB 3MZVA 3VJ9A 3WE9A 3WCHA 3VJDA 1VG2A 4JXNA 4KWDA 4NUAA 2P1CA 4JZBA 2E4OA 3SDRA 4LPHF 3KRFB 4H5DF 5IKAA 1YYSA 3VJ8A 2VF6A 3WJOA 5ILKA 3S9VA 3ZMBA 3MAVA 3KRAA 3SDVA 3LDWA 1UBXA 4L2XF 3OACB 2AZLA 1YHLA 3ZMCA 5EASA 3VJBA 3WEHA 3DYGA 2E8XA 1YYUA 3B7LA 4EA1A 5E8HA 3V66A 4E1EA 3WCAA 5B03A 3WCIA 2PS5A 5ERNA 4K10A 4ZQ8A 4N9UA 1JFAA 2OPNA 5JV0F 1VG4A 3KROA 3IBAA 4LZCA 4LFGA 4GP1A 3WEKA 5ILJA 4NFIF 3NPRA 3BNXA 4GP2A 1UBYA 3QQVA 1YHMA 3M01A 3G4DA 2E8WA 5DHIA 1WY0A 3N45F 3P8LA 4F62A 2FORA 1WL1A 4Q23A 4KPDA 5ERMA 2RAHA 4LA6A 3TC1A 3RMGA 1JFGA 1DGPA 3LZ9A 3OACA 2Z4XA 3PYAA 2J5CA 2ZY1A 2ONGA 3QKCA 5IMPA 2AZJA 3KRAB 4RXEA 2ZCQA 2Z4ZA 1HXGA 3VJCA 3LGZB 4MC8A 4DHDA 3NPKA 5CG6A 1N20A 5ILDA 1N22A 2QISA 3WEFA 2Q9YA 4JXYA 4RXCA 5IK0A 1FPSA 4KVDA 4KK2A 1VG3A 4DEMF 4KQUA 3IPIA 4LOBA 5E8KA 3AQ0A 3TFNA 1HX9A 2J1PA 3N3DA 3EZ3A 1N1BA 3M0GA 1V4HA 4LFEA 2Z52A 2F9KF 4LZ3A 3N5JF 4H5EF 5C05A 3NF2A 3ICMA 3LG5A 3ZOUA 4LTZA 3WEGA 1RQJA 4MC3A 2E90A 2PS4A 3WEJA 1YYQA 3N46F 4EA2A 3TFVA 4FJQA 3WJNA 2OPMA 3PYBA 5A0JA 3SDQA 3WJKA 3WSAA 3PKOA 3PDEA 3SAEA 4LA5A 4LXWA 5JA0F 3ZL6A 4PVXF 3ASXA 3P8RA 4JYXA 3WCDA 3AQBB 4GAXA 1N1ZA 4QPFA 1VG7A 1V4JA 2ZEVA 5DGMF 5I1UA 2E91A 2Z50A 1UBVA 2EWGA 4LZ0A 5KSXF 3Q1OA 2ZCRA 1YJ4A 2DH4A 5IVGA 3WCFA 3M00A 5IKHA 5H9DA 5IL8A 2OA6A 3ACYA 1UBWA 1HM7A 3NRIA 3LGKA 4XQTF 5JV2F 4H5CF 1WKZA 4LPGF 3LK5A 4OKMA 1DI1A 4NFJF 5B02A 2Z7IA 1EZFA 5IMNA 5DGSF 3RYEA 3OABA 2I19A 5DW7A 4XQSF 4OMHA 3KBKA 3P5RA 1ZW5A 1YHKA 4JZXA 4KUXA 3RBMA 1V4EA 4KQSA 3N3LF 4KVYA 2E95A 4OGUA 2E92A 3WCLA 2F92F 5E8LA 3P41A 4KKMA 3CP6A 1YQ7A 5IM1A 2PS6A 5DGNF 3UCAA 4DI5A 4OKZA 4RNQA 3OYRA 2AZKA 3WSBA 4E9ZA 3Q2ZA 3LSNA 4LLTA 3LMDA 3WCBA 4DWBA 4HD1A 3N0FA 2FTZA 1KIZA 1HXAA 4P0VA 2Z4YA 3KB9A 5ER8A 4GA3A 3WCCA 3TS7A 1V4KA 3APZA 3WCEA 1RTRA 3LVSA 5IK9A 3V1XA 2E93A 2E8UA 2Q80A 3N5HF 5B0JA 3DYFA 3TFPA 1N21A 2F89F 3WCMA 1YYTA 4PVYF 4KQ5A 3SDUA 2F8CF 5EAUA 3Q30A 3OABB 2H8OA 5DZ2A 3G4FA 4NG6A 2ZCSA 5B0IA 5ILIA 4E9UA 4MC0A 5JUZF 2PS7A 4F6VA 4QXSF 3KRCA 5HN8A 2AEKA 1V4IA 4WK5A 5A0KA 3N1WF 4LUUA 3AQCB 1YV5A 3N1VF 1WL2A 2Z7HA 4NKFA 3S4JA 2Z4VA 3AE0A 3Q2QA 4P0XA 1PS1A 3DYHA 4KFAA 5IL3A 3N6KF 2Z78A 4LTVA 3BNYA 2O1OA 3CC9A 3N0GA 4LIXA 3VJAA 3WEIA 2F8ZF 5HN9A 2OGDA 4P0WA 5ILHA 4KVIA 1N24A 3V1VA 3EFQA 4XQRF 4F6XA 1WL0A 5A0IA 2Z4WA 5B0KA 3EGTA 2E8TA 2ZCOA 3P5PA 1N23A 3ID0A 1VG6A 3M02A 3LJIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JVJ F;  5DJP F;  1WL3 A;  3KRP B;  5DJR F;  3SDT A;  3KRF A;  5DIQ F;  2F7M F;  4RXD A;  4LLS A;  5IN8 A;  5AHU B;  3KRC B;  1WMW A;  5JV1 F;  1RQI A;  3W7F A;  5IMI A;  1HM4 A;  3PH7 A;  4LFV F;  1HXC A;  2F94 F;  3ZCD A;  5HNA A;  3ACW A;  4N1Z F;  3ICN A;  4NFK F;  4RXA A;  4DWG A;  5HN7 A;  3LOM A;  5B0L A;  5ERO A;  5IK6 A;  2ZEU A;  3LLW A;  5B00 A;  1KIY A;  4NKE A;  2AET A;  5DHK A;  3N49 F;  5B0M A;  3ICZ A;  3CKE A;  5EAT A;  4KPJ A;  4KVW A;  3WCG A;  3M9U A;  5AYP A;  5AEL A;  3ADZ A;  4OMG A;  3VJE A;  5CG5 A;  3LEE A;  2AEL A;  2Q9Z A;  2Q58 A;  3RYW A;  5DJV F;  5ILY A;  5AFX A;  4FP4 A;  3ICK A;  4DZW A;  1YYR A;  3KRP A;  4EA0 A;  2ONH A;  5ILZ A;  3WCJ A;  2E8V A;  3ACX A;  3WC9 A;  2E94 A;  2PS8 A;  2J1O A;  4DXJ A;  4UMJ A;  5B01 A;  4RYP A;  3KRO B;  3MZV A;  3VJ9 A;  3WE9 A;  3WCH A;  3VJD A;  1VG2 A;  4JXN A;  4KWD A;  4NUA A;  2P1C A;  4JZB A;  2E4O A;  3SDR A;  4LPH F;  3KRF B;  4H5D F;  5IKA A;  1YYS A;  3VJ8 A;  2VF6 A;  3WJO A;  5ILK A;  3S9V A;  3ZMB A;  3MAV A;  3KRA A;  3SDV A;  3LDW A;  1UBX A;  4L2X F;  3OAC B;  2AZL A;  1YHL A;  3ZMC A;  5EAS A;  3VJB A;  3WEH A;  3DYG A;  2E8X A;  1YYU A;  3B7L A;  4EA1 A;  5E8H A;  3V66 A;  4E1E A;  3WCA A;  5B03 A;  3WCI A;  2PS5 A;  5ERN A;  4K10 A;  4ZQ8 A;  4N9U A;  1JFA A;  2OPN A;  5JV0 F;  1VG4 A;  3KRO A;  3IBA A;  4LZC A;  4LFG A;  4GP1 A;  3WEK A;  5ILJ A;  4NFI F;  3NPR A;  3BNX A;  4GP2 A;  1UBY A;  3QQV A;  1YHM A;  3M01 A;  3G4D A;  2E8W A;  5DHI A;  1WY0 A;  3N45 F;  3P8L A;  4F62 A;  2FOR A;  1WL1 A;  4Q23 A;  4KPD A;  5ERM A;  2RAH A;  4LA6 A;  3TC1 A;  3RMG A;  1JFG A;  1DGP A;  3LZ9 A;  3OAC A;  2Z4X A;  3PYA A;  2J5C A;  2ZY1 A;  2ONG A;  3QKC A;  5IMP A;  2AZJ A;  3KRA B;  4RXE A;  2ZCQ A;  2Z4Z A;  1HXG A;  3VJC A;  3LGZ B;  4MC8 A;  4DHD A;  3NPK A;  5CG6 A;  1N20 A;  5ILD A;  1N22 A;  2QIS A;  3WEF A;  2Q9Y A;  4JXY A;  4RXC A;  5IK0 A;  1FPS A;  4KVD A;  4KK2 A;  1VG3 A;  4DEM F;  4KQU A;  3IPI A;  4LOB A;  5E8K A;  3AQ0 A;  3TFN A;  1HX9 A;  2J1P A;  3N3D A;  3EZ3 A;  1N1B A;  3M0G A;  1V4H A;  4LFE A;  2Z52 A;  2F9K F;  4LZ3 A;  3N5J F;  4H5E F;  5C05 A;  3NF2 A;  3ICM A;  3LG5 A;  3ZOU A;  4LTZ A;  3WEG A;  1RQJ A;  4MC3 A;  2E90 A;  2PS4 A;  3WEJ A;  1YYQ A;  3N46 F;  4EA2 A;  3TFV A;  4FJQ A;  3WJN A;  2OPM A;  3PYB A;  5A0J A;  3SDQ A;  3WJK A;  3WSA A;  3PKO A;  3PDE A;  3SAE A;  4LA5 A;  4LXW A;  5JA0 F;  3ZL6 A;  4PVX F;  3ASX A;  3P8R A;  4JYX A;  3WCD A;  3AQB B;  4GAX A;  1N1Z A;  4QPF A;  1VG7 A;  1V4J A;  2ZEV A;  5DGM F;  5I1U A;  2E91 A;  2Z50 A;  1UBV A;  2EWG A;  4LZ0 A;  5KSX F;  3Q1O A;  2ZCR A;  1YJ4 A;  2DH4 A;  5IVG A;  3WCF A;  3M00 A;  5IKH A;  5H9D A;  5IL8 A;  2OA6 A;  3ACY A;  1UBW A;  1HM7 A;  3NRI A;  3LGK A;  4XQT F;  5JV2 F;  4H5C F;  1WKZ A;  4LPG F;  3LK5 A;  4OKM A;  1DI1 A;  4NFJ F;  5B02 A;  2Z7I A;  1EZF A;  5IMN A;  5DGS F;  3RYE A;  3OAB A;  2I19 A;  5DW7 A;  4XQS F;  4OMH A;  3KBK A;  3P5R A;  1ZW5 A;  1YHK A;  4JZX A;  4KUX A;  3RBM A;  1V4E A;  4KQS A;  3N3L F;  4KVY A;  2E95 A;  4OGU A;  2E92 A;  3WCL A;  2F92 F;  5E8L A;  3P41 A;  4KKM A;  3CP6 A;  1YQ7 A;  5IM1 A;  2PS6 A;  5DGN F;  3UCA A;  4DI5 A;  4OKZ A;  4RNQ A;  3OYR A;  2AZK A;  3WSB A;  4E9Z A;  3Q2Z A;  3LSN A;  4LLT A;  3LMD A;  3WCB A;  4DWB A;  4HD1 A;  3N0F A;  2FTZ A;  1KIZ A;  1HXA A;  4P0V A;  2Z4Y A;  3KB9 A;  5ER8 A;  4GA3 A;  3WCC A;  3TS7 A;  1V4K A;  3APZ A;  3WCE A;  1RTR A;  3LVS A;  5IK9 A;  3V1X A;  2E93 A;  2E8U A;  2Q80 A;  3N5H F;  5B0J A;  3DYF A;  3TFP A;  1N21 A;  2F89 F;  3WCM A;  1YYT A;  4PVY F;  4KQ5 A;  3SDU A;  2F8C F;  5EAU A;  3Q30 A;  3OAB B;  2H8O A;  5DZ2 A;  3G4F A;  4NG6 A;  2ZCS A;  5B0I A;  5ILI A;  4E9U A;  4MC0 A;  5JUZ F;  2PS7 A;  4F6V A;  4QXS F;  3KRC A;  5HN8 A;  2AEK A;  1V4I A;  4WK5 A;  5A0K A;  3N1W F;  4LUU A;  3AQC B;  1YV5 A;  3N1V F;  1WL2 A;  2Z7H A;  4NKF A;  3S4J A;  2Z4V A;  3AE0 A;  3Q2Q A;  4P0X A;  1PS1 A;  3DYH A;  4KFA A;  5IL3 A;  3N6K F;  2Z78 A;  4LTV A;  3BNY A;  2O1O A;  3CC9 A;  3N0G A;  4LIX A;  3VJA A;  3WEI A;  2F8Z F;  5HN9 A;  2OGD A;  4P0W A;  5ILH A;  4KVI A;  1N24 A;  3V1V A;  3EFQ A;  4XQR F;  4F6X A;  1WL0 A;  5A0I A;  2Z4W A;  5B0K A;  3EGT A;  2E8T A;  2ZCO A;  3P5P A;  1N23 A;  3ID0 A;  1VG6 A;  3M02 A;  3LJI A; 
#chains in the Genus database with same CATH topology
 4JVJ F;  5DJP F;  1WL3 A;  3KRP B;  5DJR F;  3SDT A;  3KRF A;  5DIQ F;  2F7M F;  4RXD A;  4LLS A;  5IN8 A;  5AHU B;  3KRC B;  1WMW A;  5JV1 F;  1RQI A;  3W7F A;  5IMI A;  1HM4 A;  3PH7 A;  4LFV F;  1HXC A;  2F94 F;  3ZCD A;  5HNA A;  3ACW A;  4N1Z F;  3ICN A;  4NFK F;  4RXA A;  4DWG A;  5HN7 A;  3LOM A;  5B0L A;  5ERO A;  5IK6 A;  2ZEU A;  3LLW A;  5B00 A;  1KIY A;  4NKE A;  2AET A;  5DHK A;  3N49 F;  5B0M A;  3ICZ A;  3CKE A;  5EAT A;  4KPJ A;  4KVW A;  3WCG A;  3M9U A;  5AYP A;  5AEL A;  3ADZ A;  4OMG A;  3VJE A;  5CG5 A;  3LEE A;  2AEL A;  2Q9Z A;  2Q58 A;  3RYW A;  5DJV F;  5ILY A;  5AFX A;  4FP4 A;  3ICK A;  4DZW A;  1YYR A;  3KRP A;  4EA0 A;  2ONH A;  5ILZ A;  3WCJ A;  2E8V A;  3ACX A;  3WC9 A;  2E94 A;  2PS8 A;  2J1O A;  4DXJ A;  4UMJ A;  5B01 A;  4RYP A;  3KRO B;  3MZV A;  3VJ9 A;  3WE9 A;  3WCH A;  3VJD A;  1VG2 A;  4JXN A;  4KWD A;  4NUA A;  2P1C A;  4JZB A;  2E4O A;  3SDR A;  4LPH F;  3KRF B;  4H5D F;  5IKA A;  1YYS A;  3VJ8 A;  2VF6 A;  3WJO A;  5ILK A;  3S9V A;  3ZMB A;  3MAV A;  3KRA A;  3SDV A;  3LDW A;  1UBX A;  4L2X F;  3OAC B;  2AZL A;  1YHL A;  3ZMC A;  5EAS A;  3VJB A;  3WEH A;  3DYG A;  2E8X A;  1YYU A;  3B7L A;  4EA1 A;  5E8H A;  3V66 A;  4E1E A;  3WCA A;  5B03 A;  3WCI A;  2PS5 A;  5ERN A;  4K10 A;  4ZQ8 A;  4N9U A;  1JFA A;  2OPN A;  5JV0 F;  1VG4 A;  3KRO A;  3IBA A;  4LZC A;  4LFG A;  4GP1 A;  3WEK A;  5ILJ A;  4NFI F;  3NPR A;  3BNX A;  4GP2 A;  1UBY A;  3QQV A;  1YHM A;  3M01 A;  3G4D A;  2E8W A;  5DHI A;  1WY0 A;  3N45 F;  3P8L A;  4F62 A;  2FOR A;  1WL1 A;  4Q23 A;  4KPD A;  5ERM A;  2RAH A;  4LA6 A;  3TC1 A;  3RMG A;  1JFG A;  1DGP A;  3LZ9 A;  3OAC A;  2Z4X A;  3PYA A;  2J5C A;  2ZY1 A;  2ONG A;  3QKC A;  5IMP A;  2AZJ A;  3KRA B;  4RXE A;  2ZCQ A;  2Z4Z A;  1HXG A;  3VJC A;  3LGZ B;  4MC8 A;  4DHD A;  3NPK A;  5CG6 A;  1N20 A;  5ILD A;  1N22 A;  2QIS A;  3WEF A;  2Q9Y A;  4JXY A;  4RXC A;  5IK0 A;  1FPS A;  4KVD A;  4KK2 A;  1VG3 A;  4DEM F;  4KQU A;  3IPI A;  4LOB A;  5E8K A;  3AQ0 A;  3TFN A;  1HX9 A;  2J1P A;  3N3D A;  3EZ3 A;  1N1B A;  3M0G A;  1V4H A;  4LFE A;  2Z52 A;  2F9K F;  4LZ3 A;  3N5J F;  4H5E F;  5C05 A;  3NF2 A;  3ICM A;  3LG5 A;  3ZOU A;  4LTZ A;  3WEG A;  1RQJ A;  4MC3 A;  2E90 A;  2PS4 A;  3WEJ A;  1YYQ A;  3N46 F;  4EA2 A;  3TFV A;  4FJQ A;  3WJN A;  2OPM A;  3PYB A;  5A0J A;  3SDQ A;  3WJK A;  3WSA A;  3PKO A;  3PDE A;  3SAE A;  4LA5 A;  4LXW A;  5JA0 F;  3ZL6 A;  4PVX F;  3ASX A;  3P8R A;  4JYX A;  3WCD A;  3AQB B;  4GAX A;  1N1Z A;  4QPF A;  1VG7 A;  1V4J A;  2ZEV A;  5DGM F;  5I1U A;  2E91 A;  2Z50 A;  1UBV A;  2EWG A;  4LZ0 A;  5KSX F;  3Q1O A;  2ZCR A;  1YJ4 A;  2DH4 A;  5IVG A;  3WCF A;  3M00 A;  5IKH A;  5H9D A;  5IL8 A;  2OA6 A;  3ACY A;  1UBW A;  1HM7 A;  3NRI A;  3LGK A;  4XQT F;  5JV2 F;  4H5C F;  1WKZ A;  4LPG F;  3LK5 A;  4OKM A;  1DI1 A;  4NFJ F;  5B02 A;  2Z7I A;  1EZF A;  5IMN A;  5DGS F;  3RYE A;  3OAB A;  2I19 A;  5DW7 A;  4XQS F;  4OMH A;  3KBK A;  3P5R A;  1ZW5 A;  1YHK A;  4JZX A;  4KUX A;  3RBM A;  1V4E A;  4KQS A;  3N3L F;  4KVY A;  2E95 A;  4OGU A;  2E92 A;  3WCL A;  2F92 F;  5E8L A;  3P41 A;  4KKM A;  3CP6 A;  1YQ7 A;  5IM1 A;  2PS6 A;  5DGN F;  3UCA A;  4DI5 A;  4OKZ A;  4RNQ A;  3OYR A;  2AZK A;  3WSB A;  4E9Z A;  3Q2Z A;  3LSN A;  4LLT A;  3LMD A;  3WCB A;  4DWB A;  4HD1 A;  3N0F A;  2FTZ A;  1KIZ A;  1HXA A;  4P0V A;  2Z4Y A;  3KB9 A;  5ER8 A;  4GA3 A;  3WCC A;  3TS7 A;  1V4K A;  3APZ A;  3WCE A;  1RTR A;  3LVS A;  5IK9 A;  3V1X A;  2E93 A;  2E8U A;  2Q80 A;  3N5H F;  5B0J A;  3DYF A;  3TFP A;  1N21 A;  2F89 F;  3WCM A;  1YYT A;  4PVY F;  4KQ5 A;  3SDU A;  2F8C F;  5EAU A;  3Q30 A;  3OAB B;  2H8O A;  5DZ2 A;  3G4F A;  4NG6 A;  2ZCS A;  5B0I A;  5ILI A;  4E9U A;  4MC0 A;  5JUZ F;  2PS7 A;  4F6V A;  4QXS F;  3KRC A;  5HN8 A;  2AEK A;  1V4I A;  4WK5 A;  5A0K A;  3N1W F;  4LUU A;  3AQC B;  1YV5 A;  3N1V F;  1WL2 A;  2Z7H A;  4NKF A;  3S4J A;  2Z4V A;  3AE0 A;  3Q2Q A;  4P0X A;  1PS1 A;  3DYH A;  4KFA A;  5IL3 A;  3N6K F;  2Z78 A;  4LTV A;  3BNY A;  2O1O A;  3CC9 A;  3N0G A;  4LIX A;  3VJA A;  3WEI A;  2F8Z F;  5HN9 A;  2OGD A;  4P0W A;  5ILH A;  4KVI A;  1N24 A;  3V1V A;  3EFQ A;  4XQR F;  4F6X A;  1WL0 A;  5A0I A;  2Z4W A;  5B0K A;  3EGT A;  2E8T A;  2ZCO A;  3P5P A;  1N23 A;  3ID0 A;  1VG6 A;  3M02 A;  3LJI A; 
#chains in the Genus database with same CATH homology
 4JVJ F;  5DJP F;  1WL3 A;  3KRP B;  5DJR F;  3SDT A;  3KRF A;  5DIQ F;  2F7M F;  4RXD A;  4LLS A;  5IN8 A;  5AHU B;  3KRC B;  1WMW A;  5JV1 F;  1RQI A;  3W7F A;  5IMI A;  1HM4 A;  3PH7 A;  4LFV F;  1HXC A;  2F94 F;  3ZCD A;  5HNA A;  3ACW A;  4N1Z F;  3ICN A;  4NFK F;  4RXA A;  4DWG A;  5HN7 A;  3LOM A;  5B0L A;  5ERO A;  5IK6 A;  2ZEU A;  3LLW A;  5B00 A;  1KIY A;  4NKE A;  2AET A;  5DHK A;  3N49 F;  5B0M A;  3ICZ A;  3CKE A;  5EAT A;  4KPJ A;  4KVW A;  3WCG A;  3M9U A;  5AYP A;  5AEL A;  3ADZ A;  4OMG A;  3VJE A;  5CG5 A;  3LEE A;  2AEL A;  2Q9Z A;  2Q58 A;  3RYW A;  5DJV F;  5ILY A;  5AFX A;  4FP4 A;  3ICK A;  4DZW A;  1YYR A;  3KRP A;  4EA0 A;  2ONH A;  5ILZ A;  3WCJ A;  2E8V A;  3ACX A;  3WC9 A;  2E94 A;  2PS8 A;  2J1O A;  4DXJ A;  4UMJ A;  5B01 A;  4RYP A;  3KRO B;  3MZV A;  3VJ9 A;  3WE9 A;  3WCH A;  3VJD A;  1VG2 A;  4JXN A;  4KWD A;  4NUA A;  2P1C A;  4JZB A;  2E4O A;  3SDR A;  4LPH F;  3KRF B;  4H5D F;  5IKA A;  1YYS A;  3VJ8 A;  2VF6 A;  3WJO A;  5ILK A;  3S9V A;  3ZMB A;  3MAV A;  3KRA A;  3SDV A;  3LDW A;  1UBX A;  4L2X F;  3OAC B;  2AZL A;  1YHL A;  3ZMC A;  5EAS A;  3VJB A;  3WEH A;  3DYG A;  2E8X A;  1YYU A;  3B7L A;  4EA1 A;  5E8H A;  3V66 A;  4E1E A;  3WCA A;  5B03 A;  3WCI A;  2PS5 A;  5ERN A;  4K10 A;  4ZQ8 A;  4N9U A;  1JFA A;  2OPN A;  5JV0 F;  1VG4 A;  3KRO A;  3IBA A;  4LZC A;  4LFG A;  4GP1 A;  3WEK A;  5ILJ A;  4NFI F;  3NPR A;  3BNX A;  4GP2 A;  1UBY A;  3QQV A;  1YHM A;  3M01 A;  3G4D A;  2E8W A;  5DHI A;  1WY0 A;  3N45 F;  3P8L A;  4F62 A;  2FOR A;  1WL1 A;  4Q23 A;  4KPD A;  5ERM A;  2RAH A;  4LA6 A;  3TC1 A;  3RMG A;  1JFG A;  1DGP A;  3LZ9 A;  3OAC A;  2Z4X A;  3PYA A;  2J5C A;  2ZY1 A;  2ONG A;  3QKC A;  5IMP A;  2AZJ A;  3KRA B;  4RXE A;  2ZCQ A;  2Z4Z A;  1HXG A;  3VJC A;  3LGZ B;  4MC8 A;  4DHD A;  3NPK A;  5CG6 A;  1N20 A;  5ILD A;  1N22 A;  2QIS A;  3WEF A;  2Q9Y A;  4JXY A;  4RXC A;  5IK0 A;  1FPS A;  4KVD A;  4KK2 A;  1VG3 A;  4DEM F;  4KQU A;  3IPI A;  4LOB A;  5E8K A;  3AQ0 A;  3TFN A;  1HX9 A;  2J1P A;  3N3D A;  3EZ3 A;  1N1B A;  3M0G A;  1V4H A;  4LFE A;  2Z52 A;  2F9K F;  4LZ3 A;  3N5J F;  4H5E F;  5C05 A;  3NF2 A;  3ICM A;  3LG5 A;  3ZOU A;  4LTZ A;  3WEG A;  1RQJ A;  4MC3 A;  2E90 A;  2PS4 A;  3WEJ A;  1YYQ A;  3N46 F;  4EA2 A;  3TFV A;  4FJQ A;  3WJN A;  2OPM A;  3PYB A;  5A0J A;  3SDQ A;  3WJK A;  3WSA A;  3PKO A;  3PDE A;  3SAE A;  4LA5 A;  4LXW A;  5JA0 F;  3ZL6 A;  4PVX F;  3ASX A;  3P8R A;  4JYX A;  3WCD A;  3AQB B;  4GAX A;  1N1Z A;  4QPF A;  1VG7 A;  1V4J A;  2ZEV A;  5DGM F;  5I1U A;  2E91 A;  2Z50 A;  1UBV A;  2EWG A;  4LZ0 A;  5KSX F;  3Q1O A;  2ZCR A;  1YJ4 A;  2DH4 A;  5IVG A;  3WCF A;  3M00 A;  5IKH A;  5H9D A;  5IL8 A;  2OA6 A;  3ACY A;  1UBW A;  1HM7 A;  3NRI A;  3LGK A;  4XQT F;  5JV2 F;  4H5C F;  1WKZ A;  4LPG F;  3LK5 A;  4OKM A;  1DI1 A;  4NFJ F;  5B02 A;  2Z7I A;  1EZF A;  5IMN A;  5DGS F;  3RYE A;  3OAB A;  2I19 A;  5DW7 A;  4XQS F;  4OMH A;  3KBK A;  3P5R A;  1ZW5 A;  1YHK A;  4JZX A;  4KUX A;  3RBM A;  1V4E A;  4KQS A;  3N3L F;  4KVY A;  2E95 A;  4OGU A;  2E92 A;  3WCL A;  2F92 F;  5E8L A;  3P41 A;  4KKM A;  3CP6 A;  1YQ7 A;  5IM1 A;  2PS6 A;  5DGN F;  3UCA A;  4DI5 A;  4OKZ A;  4RNQ A;  3OYR A;  2AZK A;  3WSB A;  4E9Z A;  3Q2Z A;  3LSN A;  4LLT A;  3LMD A;  3WCB A;  4DWB A;  4HD1 A;  3N0F A;  2FTZ A;  1KIZ A;  1HXA A;  4P0V A;  2Z4Y A;  3KB9 A;  5ER8 A;  4GA3 A;  3WCC A;  3TS7 A;  1V4K A;  3APZ A;  3WCE A;  1RTR A;  3LVS A;  5IK9 A;  3V1X A;  2E93 A;  2E8U A;  2Q80 A;  3N5H F;  5B0J A;  3DYF A;  3TFP A;  1N21 A;  2F89 F;  3WCM A;  1YYT A;  4PVY F;  4KQ5 A;  3SDU A;  2F8C F;  5EAU A;  3Q30 A;  3OAB B;  2H8O A;  5DZ2 A;  3G4F A;  4NG6 A;  2ZCS A;  5B0I A;  5ILI A;  4E9U A;  4MC0 A;  5JUZ F;  2PS7 A;  4F6V A;  4QXS F;  3KRC A;  5HN8 A;  2AEK A;  1V4I A;  4WK5 A;  5A0K A;  3N1W F;  4LUU A;  3AQC B;  1YV5 A;  3N1V F;  1WL2 A;  2Z7H A;  4NKF A;  3S4J A;  2Z4V A;  3AE0 A;  3Q2Q A;  4P0X A;  1PS1 A;  3DYH A;  4KFA A;  5IL3 A;  3N6K F;  2Z78 A;  4LTV A;  3BNY A;  2O1O A;  3CC9 A;  3N0G A;  4LIX A;  3VJA A;  3WEI A;  2F8Z F;  5HN9 A;  2OGD A;  4P0W A;  5ILH A;  4KVI A;  1N24 A;  3V1V A;  3EFQ A;  4XQR F;  4F6X A;  1WL0 A;  5A0I A;  2Z4W A;  5B0K A;  3EGT A;  2E8T A;  2ZCO A;  3P5P A;  1N23 A;  3ID0 A;  1VG6 A;  3M02 A;  3LJI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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