3ICNA

Trypanosoma cruzi farnesyl diphosphate synthase homodimer in complex with isopentenyl pyrophosphate and 3-fluoro-1-(2-hydroxy-2,2-bis-phosphono-ethyl)-pyridinium
Total Genus 148
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
148
sequence length
362
structure length
362
Chain Sequence
MASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYFRGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDIMDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLKDLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIYKRIVKYKTTFYTYLLPLVMGLFVSEAAASVEMNLVERVAHLIGEYFQVQDDVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGDKDPAKVAVVKRLYSEANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESVAVVWEKTHKRKK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer.
pubmed doi rcsb
molecule keywords Farnesyl pyrophosphate synthase
molecule tags Transferase
source organism Trypanosoma cruzi
total genus 148
structure length 362
sequence length 362
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2009-07-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3icnA00
3OABA 3ICZA 4Q23A 3N5JF 2OPNA 3OACA 3WCJA 2Z50A 1HX9A 2ZEVA 3TS7A 1RQJA 3TFPA 4LLTA 3KRFB 4LOBA 4RXDA 3BNYA 4LA6A 3M02A 5ILYA 1V4EA 5EATA 3PDEA 3PYAA 3KRFA 4F62A 5A0IA 4KKMA 4NUAA 3Q2QA 4E9UA 3WCIA 2ZCSA 4H5CF 4XQSF 4FJQA 5A0KA 5IM1A 3RMGA 3NPRA 4GA3A 4L2XF 1VG2A 4RNQA 5IK6A 3P41A 3DYGA 4N9UA 3WCBA 3S4JA 3V1XA 5ILDA 4RXCA 5ILKA 5IK0A 5IL8A 3WCHA 3ZCDA 3ACWA 4NFJF 3G4FA 3OYRA 3KRCB 1EZFA 5IK9A 3ICNA 5E8LA 2F94F 2F9KF 3ID0A 2E8XA 4HD1A 2E8UA 3VJ8A 5CG6A 2Q80A 1UBWA 2Z4ZA 2O1OA 1UBVA 3RBMA 4KVDA 4OKZA 3V66A 2DH4A 3SDVA 3WE9A 5JV2F 3AE0A 1VG7A 2P1CA 3WEFA 5HN9A 1YHMA 4XQRF 1N22A 5H9DA 4JZBA 5DJPF 5E8HA 4OMGA 2PS4A 4GP1A 1N24A 4LTVA 3WEKA 3WEIA 2QISA 2Z4XA 4NKEA 3RYWA 2E95A 3V1VA 3LG5A 2AETA 3N45F 3QQVA 5ER8A 3LMDA 5B0KA 4PVYF 5ILHA 5HNAA 4LPHF 3LK5A 3DYHA 2PS6A 5C05A 3KRAB 2E94A 3NRIA 1N1BA 5EASA 3PH7A 1WL2A 4XQTF 4P0XA 3WEGA 3KRAA 4DI5A 2H8OA 5HN8A 5B0IA 2F8ZF 5JV0F 1YHKA 4E9ZA 3WEJA 4N1ZF 4LXWA 5DGNF 2ONHA 3N49F 4RXAA 5KSXF 4NFKF 3VJ9A 5IL3A 2VF6A 1YHLA 4KQSA 4DWGA 3VJCA 4LFEA 3CKEA 2ZCOA 5JUZF 3ZOUA 5DW7A 4KUXA 4P0VA 2OA6A 3LEEA 5DGMF 2E90A 5DIQF 2AZJA 3NF2A 5ILIA 2E92A 3WCLA 5B00A 3WSAA 4KVIA 1YQ7A 4QXSF 3LZ9A 1YYRA 1ZW5A 4F6VA 4OKMA 2RAHA 1V4HA 3ZMBA 3G4DA 1JFAA 5EROA 3SDQA 3ZL6A 1WL1A 1FPSA 2AELA 1V4KA 2E8TA 3B7LA 3VJDA 3ZMCA 4KQUA 4MC3A 3BNXA 3P5RA 3IPIA 3KROB 2FTZA 3QKCA 5B0MA 3DYFA 3ACYA 5B02A 3LVSA 3N5HF 3VJBA 1JFGA 4RYPA 3KRCA 4EA2A 3RYEA 4DWBA 2AZKA 3KB9A 4DXJA 2ZY1A 5IMNA 3Q30A 3SDRA 2J1PA 2Z52A 2Z78A 4LZCA 3N1VF 3WEHA 2ZEUA 1PS1A 5AHUB 1HXCA 3VJEA 2Q9YA 4KPJA 5JA0F 1WMWA 4ZQ8A 2F89F 4OGUA 4DHDA 3M0GA 4WK5A 3N0GA 4LFGA 3WCCA 5IMPA 2ZCRA 3KRPB 4LZ0A 4JXYA 4E1EA 1YYTA 3CC9A 5HN7A 2OGDA 2Q58A 5A0JA 5DJVF 5CG5A 3WJKA 5B01A 2PS5A 5AELA 4FP4A 5IVGA 2E8WA 3ICKA 3WSBA 4KWDA 4KFAA 2E8VA 1DI1A 2AEKA 1HXGA 5IN8A 1N21A 2Z7HA 1N20A 3P8LA 3LLWA 5EAUA 3VJAA 3N3DA 2Z4VA 3NPKA 4NG6A 1HM7A 1VG4A 2Q9ZA 4LUUA 3W7FA 3ASXA 4GAXA 3SDTA 1RTRA 3WJOA 4JXNA 3OABB 3N46F 5ILJA 3AQ0A 3OACB 3N6KF 3APZA 5DGSF 2F8CF 5E8KA 3N0FA 2I19A 3MAVA 4OMHA 2Z4YA 5IKAA 2Z7IA 5IKHA 3WCAA 3ICMA 4LLSA 3P8RA 3SDUA 3PKOA 2Z4WA 3EZ3A 4KK2A 2OPMA 4LPGF 5DJRF 4KVWA 4LTZA 3LSNA 1UBYA 3IBAA 2E91A 1WKZA 2PS7A 2F92F 3LOMA 3LGKA 3KROA 1N23A 4UMJA 5ERNA 5B03A 3EFQA 1UBXA 4MC0A 3MZVA 3LDWA 1DGPA 1VG3A 3S9VA 2ZCQA 1YYQA 5DHKA 3TFVA 4RXEA 1RQIA 4JZXA 3M00A 1WL0A 2ONGA 3EGTA 3KBKA 3WCEA 2AZLA 5B0LA 4DZWA 4NKFA 3WCDA 1HM4A 5DZ2A 3TC1A 2EWGA 4KPDA 3M9UA 3Q1OA 4QPFA 4LA5A 3UCAA 4EA1A 3WCFA 4K10A 2E4OA 4JVJF 3LGZB 4MC8A 2PS8A 3ACXA 1YV5A 4F6XA 3ADZA 3SAEA 5JV1F 3PYBA 5DHIA 4JYXA 3WCMA 1HXAA 1WY0A 5AYPA 3KRPA 5I1UA 1KIYA 2E93A 3LJIA 1N1ZA 4LZ3A 1YJ4A 2J5CA 5IMIA 1KIZA 2FORA 5AFXA 4LFVF 1WL3A 1V4IA 4LIXA 3M01A 3WJNA 2J1OA 3Q2ZA 5ERMA 4EA0A 4H5EF 4KQ5A 4DEMF 1YYSA 4NFIF 4H5DF 3TFNA 3N1WF 3N3LF 3WC9A 1VG6A 4P0WA 2F7MF 3WCGA 4GP2A 3AQCB 4KVYA 5B0JA 3CP6A 5ILZA 4PVXF 1V4JA 3P5PA 3AQBB 1YYUA
chains in the Genus database with same CATH superfamily
3OABA 3ICZA 4Q23A 3N5JF 2OPNA 3OACA 3WCJA 2Z50A 1HX9A 2ZEVA 3TS7A 1RQJA 3TFPA 4LLTA 3KRFB 4LOBA 4RXDA 3BNYA 4LA6A 3M02A 5ILYA 1V4EA 5EATA 3PDEA 3PYAA 3KRFA 4F62A 5A0IA 4KKMA 4NUAA 3Q2QA 4E9UA 3WCIA 2ZCSA 4H5CF 4XQSF 4FJQA 5A0KA 5IM1A 3RMGA 3NPRA 4GA3A 4L2XF 1VG2A 4RNQA 5IK6A 3P41A 3DYGA 4N9UA 3WCBA 3S4JA 3V1XA 5ILDA 4RXCA 5ILKA 5IK0A 5IL8A 3WCHA 3ZCDA 3ACWA 4NFJF 3G4FA 3OYRA 3KRCB 1EZFA 5IK9A 3ICNA 5E8LA 2F94F 2F9KF 3ID0A 2E8XA 4HD1A 2E8UA 3VJ8A 5CG6A 2Q80A 1UBWA 2Z4ZA 2O1OA 1UBVA 3RBMA 4KVDA 4OKZA 3V66A 2DH4A 3SDVA 3WE9A 5JV2F 3AE0A 1VG7A 2P1CA 3WEFA 5HN9A 1YHMA 4XQRF 1N22A 5H9DA 4JZBA 5DJPF 5E8HA 4OMGA 2PS4A 4GP1A 1N24A 4LTVA 3WEKA 3WEIA 2QISA 2Z4XA 4NKEA 3RYWA 2E95A 3V1VA 3LG5A 2AETA 3N45F 3QQVA 5ER8A 3LMDA 5B0KA 4PVYF 5ILHA 5HNAA 4LPHF 3LK5A 3DYHA 2PS6A 5C05A 3KRAB 2E94A 3NRIA 1N1BA 5EASA 3PH7A 1WL2A 4XQTF 4P0XA 3WEGA 3KRAA 4DI5A 2H8OA 5HN8A 5B0IA 2F8ZF 5JV0F 1YHKA 4E9ZA 3WEJA 4N1ZF 4LXWA 5DGNF 2ONHA 3N49F 4RXAA 5KSXF 4NFKF 3VJ9A 5IL3A 2VF6A 1YHLA 4KQSA 4DWGA 3VJCA 4LFEA 3CKEA 2ZCOA 5JUZF 3ZOUA 5DW7A 4KUXA 4P0VA 2OA6A 3LEEA 5DGMF 2E90A 5DIQF 2AZJA 3NF2A 5ILIA 2E92A 3WCLA 5B00A 3WSAA 4KVIA 1YQ7A 4QXSF 3LZ9A 1YYRA 1ZW5A 4F6VA 4OKMA 2RAHA 1V4HA 3ZMBA 3G4DA 1JFAA 5EROA 3SDQA 3ZL6A 1WL1A 1FPSA 2AELA 1V4KA 2E8TA 3B7LA 3VJDA 3ZMCA 4KQUA 4MC3A 3BNXA 3P5RA 3IPIA 3KROB 2FTZA 3QKCA 5B0MA 3DYFA 3ACYA 5B02A 3LVSA 3N5HF 3VJBA 1JFGA 4RYPA 3KRCA 4EA2A 3RYEA 4DWBA 2AZKA 3KB9A 4DXJA 2ZY1A 5IMNA 3Q30A 3SDRA 2J1PA 2Z52A 2Z78A 4LZCA 3N1VF 3WEHA 2ZEUA 1PS1A 5AHUB 1HXCA 3VJEA 2Q9YA 4KPJA 5JA0F 1WMWA 4ZQ8A 2F89F 4OGUA 4DHDA 3M0GA 4WK5A 3N0GA 4LFGA 3WCCA 5IMPA 2ZCRA 3KRPB 4LZ0A 4JXYA 4E1EA 1YYTA 3CC9A 5HN7A 2OGDA 2Q58A 5A0JA 5DJVF 5CG5A 3WJKA 5B01A 2PS5A 5AELA 4FP4A 5IVGA 2E8WA 3ICKA 3WSBA 4KWDA 4KFAA 2E8VA 1DI1A 2AEKA 1HXGA 5IN8A 1N21A 2Z7HA 1N20A 3P8LA 3LLWA 5EAUA 3VJAA 3N3DA 2Z4VA 3NPKA 4NG6A 1HM7A 1VG4A 2Q9ZA 4LUUA 3W7FA 3ASXA 4GAXA 3SDTA 1RTRA 3WJOA 4JXNA 3OABB 3N46F 5ILJA 3AQ0A 3OACB 3N6KF 3APZA 5DGSF 2F8CF 5E8KA 3N0FA 2I19A 3MAVA 4OMHA 2Z4YA 5IKAA 2Z7IA 5IKHA 3WCAA 3ICMA 4LLSA 3P8RA 3SDUA 3PKOA 2Z4WA 3EZ3A 4KK2A 2OPMA 4LPGF 5DJRF 4KVWA 4LTZA 3LSNA 1UBYA 3IBAA 2E91A 1WKZA 2PS7A 2F92F 3LOMA 3LGKA 3KROA 1N23A 4UMJA 5ERNA 5B03A 3EFQA 1UBXA 4MC0A 3MZVA 3LDWA 1DGPA 1VG3A 3S9VA 2ZCQA 1YYQA 5DHKA 3TFVA 4RXEA 1RQIA 4JZXA 3M00A 1WL0A 2ONGA 3EGTA 3KBKA 3WCEA 2AZLA 5B0LA 4DZWA 4NKFA 3WCDA 1HM4A 5DZ2A 3TC1A 2EWGA 4KPDA 3M9UA 3Q1OA 4QPFA 4LA5A 3UCAA 4EA1A 3WCFA 4K10A 2E4OA 4JVJF 3LGZB 4MC8A 2PS8A 3ACXA 1YV5A 4F6XA 3ADZA 3SAEA 5JV1F 3PYBA 5DHIA 4JYXA 3WCMA 1HXAA 1WY0A 5AYPA 3KRPA 5I1UA 1KIYA 2E93A 3LJIA 1N1ZA 4LZ3A 1YJ4A 2J5CA 5IMIA 1KIZA 2FORA 5AFXA 4LFVF 1WL3A 1V4IA 4LIXA 3M01A 3WJNA 2J1OA 3Q2ZA 5ERMA 4EA0A 4H5EF 4KQ5A 4DEMF 1YYSA 4NFIF 4H5DF 3TFNA 3N1WF 3N3LF 3WC9A 1VG6A 4P0WA 2F7MF 3WCGA 4GP2A 3AQCB 4KVYA 5B0JA 3CP6A 5ILZA 4PVXF 1V4JA 3P5PA 3AQBB 1YYUA
chains in the Genus database with same CATH topology
3OABA 3ICZA 4Q23A 3N5JF 2OPNA 3OACA 3WCJA 2Z50A 1HX9A 2ZEVA 3TS7A 1RQJA 3TFPA 4LLTA 3KRFB 4LOBA 4RXDA 3BNYA 4LA6A 3M02A 5ILYA 1V4EA 5EATA 3PDEA 3PYAA 3KRFA 4F62A 5A0IA 4KKMA 4NUAA 3Q2QA 4E9UA 3WCIA 2ZCSA 4H5CF 4XQSF 4FJQA 5A0KA 5IM1A 3RMGA 3NPRA 4GA3A 4L2XF 1VG2A 4RNQA 5IK6A 3P41A 3DYGA 4N9UA 3WCBA 3S4JA 3V1XA 5ILDA 4RXCA 5ILKA 5IK0A 5IL8A 3WCHA 3ZCDA 3ACWA 4NFJF 3G4FA 3OYRA 3KRCB 1EZFA 5IK9A 3ICNA 5E8LA 2F94F 2F9KF 3ID0A 2E8XA 4HD1A 2E8UA 3VJ8A 5CG6A 2Q80A 1UBWA 2Z4ZA 2O1OA 1UBVA 3RBMA 4KVDA 4OKZA 3V66A 2DH4A 3SDVA 3WE9A 5JV2F 3AE0A 1VG7A 2P1CA 3WEFA 5HN9A 1YHMA 4XQRF 1N22A 5H9DA 4JZBA 5DJPF 5E8HA 4OMGA 2PS4A 4GP1A 1N24A 4LTVA 3WEKA 3WEIA 2QISA 2Z4XA 4NKEA 3RYWA 2E95A 3V1VA 3LG5A 2AETA 3N45F 3QQVA 5ER8A 3LMDA 5B0KA 4PVYF 5ILHA 5HNAA 4LPHF 3LK5A 3DYHA 2PS6A 5C05A 3KRAB 2E94A 3NRIA 1N1BA 5EASA 3PH7A 1WL2A 4XQTF 4P0XA 3WEGA 3KRAA 4DI5A 2H8OA 5HN8A 5B0IA 2F8ZF 5JV0F 1YHKA 4E9ZA 3WEJA 4N1ZF 4LXWA 5DGNF 2ONHA 3N49F 4RXAA 5KSXF 4NFKF 3VJ9A 5IL3A 2VF6A 1YHLA 4KQSA 4DWGA 3VJCA 4LFEA 3CKEA 2ZCOA 5JUZF 3ZOUA 5DW7A 4KUXA 4P0VA 2OA6A 3LEEA 5DGMF 2E90A 5DIQF 2AZJA 3NF2A 5ILIA 2E92A 3WCLA 5B00A 3WSAA 4KVIA 1YQ7A 4QXSF 3LZ9A 1YYRA 1ZW5A 4F6VA 4OKMA 2RAHA 1V4HA 3ZMBA 3G4DA 1JFAA 5EROA 3SDQA 3ZL6A 1WL1A 1FPSA 2AELA 1V4KA 2E8TA 3B7LA 3VJDA 3ZMCA 4KQUA 4MC3A 3BNXA 3P5RA 3IPIA 3KROB 2FTZA 3QKCA 5B0MA 3DYFA 3ACYA 5B02A 3LVSA 3N5HF 3VJBA 1JFGA 4RYPA 3KRCA 4EA2A 3RYEA 4DWBA 2AZKA 3KB9A 4DXJA 2ZY1A 5IMNA 3Q30A 3SDRA 2J1PA 2Z52A 2Z78A 4LZCA 3N1VF 3WEHA 2ZEUA 1PS1A 5AHUB 1HXCA 3VJEA 2Q9YA 4KPJA 5JA0F 1WMWA 4ZQ8A 2F89F 4OGUA 4DHDA 3M0GA 4WK5A 3N0GA 4LFGA 3WCCA 5IMPA 2ZCRA 3KRPB 4LZ0A 4JXYA 4E1EA 1YYTA 3CC9A 5HN7A 2OGDA 2Q58A 5A0JA 5DJVF 5CG5A 3WJKA 5B01A 2PS5A 5AELA 4FP4A 5IVGA 2E8WA 3ICKA 3WSBA 4KWDA 4KFAA 2E8VA 1DI1A 2AEKA 1HXGA 5IN8A 1N21A 2Z7HA 1N20A 3P8LA 3LLWA 5EAUA 3VJAA 3N3DA 2Z4VA 3NPKA 4NG6A 1HM7A 1VG4A 2Q9ZA 4LUUA 3W7FA 3ASXA 4GAXA 3SDTA 1RTRA 3WJOA 4JXNA 3OABB 3N46F 5ILJA 3AQ0A 3OACB 3N6KF 3APZA 5DGSF 2F8CF 5E8KA 3N0FA 2I19A 3MAVA 4OMHA 2Z4YA 5IKAA 2Z7IA 5IKHA 3WCAA 3ICMA 4LLSA 3P8RA 3SDUA 3PKOA 2Z4WA 3EZ3A 4KK2A 2OPMA 4LPGF 5DJRF 4KVWA 4LTZA 3LSNA 1UBYA 3IBAA 2E91A 1WKZA 2PS7A 2F92F 3LOMA 3LGKA 3KROA 1N23A 4UMJA 5ERNA 5B03A 3EFQA 1UBXA 4MC0A 3MZVA 3LDWA 1DGPA 1VG3A 3S9VA 2ZCQA 1YYQA 5DHKA 3TFVA 4RXEA 1RQIA 4JZXA 3M00A 1WL0A 2ONGA 3EGTA 3KBKA 3WCEA 2AZLA 5B0LA 4DZWA 4NKFA 3WCDA 1HM4A 5DZ2A 3TC1A 2EWGA 4KPDA 3M9UA 3Q1OA 4QPFA 4LA5A 3UCAA 4EA1A 3WCFA 4K10A 2E4OA 4JVJF 3LGZB 4MC8A 2PS8A 3ACXA 1YV5A 4F6XA 3ADZA 3SAEA 5JV1F 3PYBA 5DHIA 4JYXA 3WCMA 1HXAA 1WY0A 5AYPA 3KRPA 5I1UA 1KIYA 2E93A 3LJIA 1N1ZA 4LZ3A 1YJ4A 2J5CA 5IMIA 1KIZA 2FORA 5AFXA 4LFVF 1WL3A 1V4IA 4LIXA 3M01A 3WJNA 2J1OA 3Q2ZA 5ERMA 4EA0A 4H5EF 4KQ5A 4DEMF 1YYSA 4NFIF 4H5DF 3TFNA 3N1WF 3N3LF 3WC9A 1VG6A 4P0WA 2F7MF 3WCGA 4GP2A 3AQCB 4KVYA 5B0JA 3CP6A 5ILZA 4PVXF 1V4JA 3P5PA 3AQBB 1YYUA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3OAB A;  3ICZ A;  4Q23 A;  3N5J F;  2OPN A;  3OAC A;  3WCJ A;  2Z50 A;  1HX9 A;  2ZEV A;  3TS7 A;  1RQJ A;  3TFP A;  4LLT A;  3KRF B;  4LOB A;  4RXD A;  3BNY A;  4LA6 A;  3M02 A;  5ILY A;  1V4E A;  5EAT A;  3PDE A;  3PYA A;  3KRF A;  4F62 A;  5A0I A;  4KKM A;  4NUA A;  3Q2Q A;  4E9U A;  3WCI A;  2ZCS A;  4H5C F;  4XQS F;  4FJQ A;  5A0K A;  5IM1 A;  3RMG A;  3NPR A;  4GA3 A;  4L2X F;  1VG2 A;  4RNQ A;  5IK6 A;  3P41 A;  3DYG A;  4N9U A;  3WCB A;  3S4J A;  3V1X A;  5ILD A;  4RXC A;  5ILK A;  5IK0 A;  5IL8 A;  3WCH A;  3ZCD A;  3ACW A;  4NFJ F;  3G4F A;  3OYR A;  3KRC B;  1EZF A;  5IK9 A;  3ICN A;  5E8L A;  2F94 F;  2F9K F;  3ID0 A;  2E8X A;  4HD1 A;  2E8U A;  3VJ8 A;  5CG6 A;  2Q80 A;  1UBW A;  2Z4Z A;  2O1O A;  1UBV A;  3RBM A;  4KVD A;  4OKZ A;  3V66 A;  2DH4 A;  3SDV A;  3WE9 A;  5JV2 F;  3AE0 A;  1VG7 A;  2P1C A;  3WEF A;  5HN9 A;  1YHM A;  4XQR F;  1N22 A;  5H9D A;  4JZB A;  5DJP F;  5E8H A;  4OMG A;  2PS4 A;  4GP1 A;  1N24 A;  4LTV A;  3WEK A;  3WEI A;  2QIS A;  2Z4X A;  4NKE A;  3RYW A;  2E95 A;  3V1V A;  3LG5 A;  2AET A;  3N45 F;  3QQV A;  5ER8 A;  3LMD A;  5B0K A;  4PVY F;  5ILH A;  5HNA A;  4LPH F;  3LK5 A;  3DYH A;  2PS6 A;  5C05 A;  3KRA B;  2E94 A;  3NRI A;  1N1B A;  5EAS A;  3PH7 A;  1WL2 A;  4XQT F;  4P0X A;  3WEG A;  3KRA A;  4DI5 A;  2H8O A;  5HN8 A;  5B0I A;  2F8Z F;  5JV0 F;  1YHK A;  4E9Z A;  3WEJ A;  4N1Z F;  4LXW A;  5DGN F;  2ONH A;  3N49 F;  4RXA A;  5KSX F;  4NFK F;  3VJ9 A;  5IL3 A;  2VF6 A;  1YHL A;  4KQS A;  4DWG A;  3VJC A;  4LFE A;  3CKE A;  2ZCO A;  5JUZ F;  3ZOU A;  5DW7 A;  4KUX A;  4P0V A;  2OA6 A;  3LEE A;  5DGM F;  2E90 A;  5DIQ F;  2AZJ A;  3NF2 A;  5ILI A;  2E92 A;  3WCL A;  5B00 A;  3WSA A;  4KVI A;  1YQ7 A;  4QXS F;  3LZ9 A;  1YYR A;  1ZW5 A;  4F6V A;  4OKM A;  2RAH A;  1V4H A;  3ZMB A;  3G4D A;  1JFA A;  5ERO A;  3SDQ A;  3ZL6 A;  1WL1 A;  1FPS A;  2AEL A;  1V4K A;  2E8T A;  3B7L A;  3VJD A;  3ZMC A;  4KQU A;  4MC3 A;  3BNX A;  3P5R A;  3IPI A;  3KRO B;  2FTZ A;  3QKC A;  5B0M A;  3DYF A;  3ACY A;  5B02 A;  3LVS A;  3N5H F;  3VJB A;  1JFG A;  4RYP A;  3KRC A;  4EA2 A;  3RYE A;  4DWB A;  2AZK A;  3KB9 A;  4DXJ A;  2ZY1 A;  5IMN A;  3Q30 A;  3SDR A;  2J1P A;  2Z52 A;  2Z78 A;  4LZC A;  3N1V F;  3WEH A;  2ZEU A;  1PS1 A;  5AHU B;  1HXC A;  3VJE A;  2Q9Y A;  4KPJ A;  5JA0 F;  1WMW A;  4ZQ8 A;  2F89 F;  4OGU A;  4DHD A;  3M0G A;  4WK5 A;  3N0G A;  4LFG A;  3WCC A;  5IMP A;  2ZCR A;  3KRP B;  4LZ0 A;  4JXY A;  4E1E A;  1YYT A;  3CC9 A;  5HN7 A;  2OGD A;  2Q58 A;  5A0J A;  5DJV F;  5CG5 A;  3WJK A;  5B01 A;  2PS5 A;  5AEL A;  4FP4 A;  5IVG A;  2E8W A;  3ICK A;  3WSB A;  4KWD A;  4KFA A;  2E8V A;  1DI1 A;  2AEK A;  1HXG A;  5IN8 A;  1N21 A;  2Z7H A;  1N20 A;  3P8L A;  3LLW A;  5EAU A;  3VJA A;  3N3D A;  2Z4V A;  3NPK A;  4NG6 A;  1HM7 A;  1VG4 A;  2Q9Z A;  4LUU A;  3W7F A;  3ASX A;  4GAX A;  3SDT A;  1RTR A;  3WJO A;  4JXN A;  3OAB B;  3N46 F;  5ILJ A;  3AQ0 A;  3OAC B;  3N6K F;  3APZ A;  5DGS F;  2F8C F;  5E8K A;  3N0F A;  2I19 A;  3MAV A;  4OMH A;  2Z4Y A;  5IKA A;  2Z7I A;  5IKH A;  3WCA A;  3ICM A;  4LLS A;  3P8R A;  3SDU A;  3PKO A;  2Z4W A;  3EZ3 A;  4KK2 A;  2OPM A;  4LPG F;  5DJR F;  4KVW A;  4LTZ A;  3LSN A;  1UBY A;  3IBA A;  2E91 A;  1WKZ A;  2PS7 A;  2F92 F;  3LOM A;  3LGK A;  3KRO A;  1N23 A;  4UMJ A;  5ERN A;  5B03 A;  3EFQ A;  1UBX A;  4MC0 A;  3MZV A;  3LDW A;  1DGP A;  1VG3 A;  3S9V A;  2ZCQ A;  1YYQ A;  5DHK A;  3TFV A;  4RXE A;  1RQI A;  4JZX A;  3M00 A;  1WL0 A;  2ONG A;  3EGT A;  3KBK A;  3WCE A;  2AZL A;  5B0L A;  4DZW A;  4NKF A;  3WCD A;  1HM4 A;  5DZ2 A;  3TC1 A;  2EWG A;  4KPD A;  3M9U A;  3Q1O A;  4QPF A;  4LA5 A;  3UCA A;  4EA1 A;  3WCF A;  4K10 A;  2E4O A;  4JVJ F;  3LGZ B;  4MC8 A;  2PS8 A;  3ACX A;  1YV5 A;  4F6X A;  3ADZ A;  3SAE A;  5JV1 F;  3PYB A;  5DHI A;  4JYX A;  3WCM A;  1HXA A;  1WY0 A;  5AYP A;  3KRP A;  5I1U A;  1KIY A;  2E93 A;  3LJI A;  1N1Z A;  4LZ3 A;  1YJ4 A;  2J5C A;  5IMI A;  1KIZ A;  2FOR A;  5AFX A;  4LFV F;  1WL3 A;  1V4I A;  4LIX A;  3M01 A;  3WJN A;  2J1O A;  3Q2Z A;  5ERM A;  4EA0 A;  4H5E F;  4KQ5 A;  4DEM F;  1YYS A;  4NFI F;  4H5D F;  3TFN A;  3N1W F;  3N3L F;  3WC9 A;  1VG6 A;  4P0W A;  2F7M F;  3WCG A;  4GP2 A;  3AQC B;  4KVY A;  5B0J A;  3CP6 A;  5ILZ A;  4PVX F;  1V4J A;  3P5P A;  3AQB B;  1YYU A; 
#chains in the Genus database with same CATH topology
 3OAB A;  3ICZ A;  4Q23 A;  3N5J F;  2OPN A;  3OAC A;  3WCJ A;  2Z50 A;  1HX9 A;  2ZEV A;  3TS7 A;  1RQJ A;  3TFP A;  4LLT A;  3KRF B;  4LOB A;  4RXD A;  3BNY A;  4LA6 A;  3M02 A;  5ILY A;  1V4E A;  5EAT A;  3PDE A;  3PYA A;  3KRF A;  4F62 A;  5A0I A;  4KKM A;  4NUA A;  3Q2Q A;  4E9U A;  3WCI A;  2ZCS A;  4H5C F;  4XQS F;  4FJQ A;  5A0K A;  5IM1 A;  3RMG A;  3NPR A;  4GA3 A;  4L2X F;  1VG2 A;  4RNQ A;  5IK6 A;  3P41 A;  3DYG A;  4N9U A;  3WCB A;  3S4J A;  3V1X A;  5ILD A;  4RXC A;  5ILK A;  5IK0 A;  5IL8 A;  3WCH A;  3ZCD A;  3ACW A;  4NFJ F;  3G4F A;  3OYR A;  3KRC B;  1EZF A;  5IK9 A;  3ICN A;  5E8L A;  2F94 F;  2F9K F;  3ID0 A;  2E8X A;  4HD1 A;  2E8U A;  3VJ8 A;  5CG6 A;  2Q80 A;  1UBW A;  2Z4Z A;  2O1O A;  1UBV A;  3RBM A;  4KVD A;  4OKZ A;  3V66 A;  2DH4 A;  3SDV A;  3WE9 A;  5JV2 F;  3AE0 A;  1VG7 A;  2P1C A;  3WEF A;  5HN9 A;  1YHM A;  4XQR F;  1N22 A;  5H9D A;  4JZB A;  5DJP F;  5E8H A;  4OMG A;  2PS4 A;  4GP1 A;  1N24 A;  4LTV A;  3WEK A;  3WEI A;  2QIS A;  2Z4X A;  4NKE A;  3RYW A;  2E95 A;  3V1V A;  3LG5 A;  2AET A;  3N45 F;  3QQV A;  5ER8 A;  3LMD A;  5B0K A;  4PVY F;  5ILH A;  5HNA A;  4LPH F;  3LK5 A;  3DYH A;  2PS6 A;  5C05 A;  3KRA B;  2E94 A;  3NRI A;  1N1B A;  5EAS A;  3PH7 A;  1WL2 A;  4XQT F;  4P0X A;  3WEG A;  3KRA A;  4DI5 A;  2H8O A;  5HN8 A;  5B0I A;  2F8Z F;  5JV0 F;  1YHK A;  4E9Z A;  3WEJ A;  4N1Z F;  4LXW A;  5DGN F;  2ONH A;  3N49 F;  4RXA A;  5KSX F;  4NFK F;  3VJ9 A;  5IL3 A;  2VF6 A;  1YHL A;  4KQS A;  4DWG A;  3VJC A;  4LFE A;  3CKE A;  2ZCO A;  5JUZ F;  3ZOU A;  5DW7 A;  4KUX A;  4P0V A;  2OA6 A;  3LEE A;  5DGM F;  2E90 A;  5DIQ F;  2AZJ A;  3NF2 A;  5ILI A;  2E92 A;  3WCL A;  5B00 A;  3WSA A;  4KVI A;  1YQ7 A;  4QXS F;  3LZ9 A;  1YYR A;  1ZW5 A;  4F6V A;  4OKM A;  2RAH A;  1V4H A;  3ZMB A;  3G4D A;  1JFA A;  5ERO A;  3SDQ A;  3ZL6 A;  1WL1 A;  1FPS A;  2AEL A;  1V4K A;  2E8T A;  3B7L A;  3VJD A;  3ZMC A;  4KQU A;  4MC3 A;  3BNX A;  3P5R A;  3IPI A;  3KRO B;  2FTZ A;  3QKC A;  5B0M A;  3DYF A;  3ACY A;  5B02 A;  3LVS A;  3N5H F;  3VJB A;  1JFG A;  4RYP A;  3KRC A;  4EA2 A;  3RYE A;  4DWB A;  2AZK A;  3KB9 A;  4DXJ A;  2ZY1 A;  5IMN A;  3Q30 A;  3SDR A;  2J1P A;  2Z52 A;  2Z78 A;  4LZC A;  3N1V F;  3WEH A;  2ZEU A;  1PS1 A;  5AHU B;  1HXC A;  3VJE A;  2Q9Y A;  4KPJ A;  5JA0 F;  1WMW A;  4ZQ8 A;  2F89 F;  4OGU A;  4DHD A;  3M0G A;  4WK5 A;  3N0G A;  4LFG A;  3WCC A;  5IMP A;  2ZCR A;  3KRP B;  4LZ0 A;  4JXY A;  4E1E A;  1YYT A;  3CC9 A;  5HN7 A;  2OGD A;  2Q58 A;  5A0J A;  5DJV F;  5CG5 A;  3WJK A;  5B01 A;  2PS5 A;  5AEL A;  4FP4 A;  5IVG A;  2E8W A;  3ICK A;  3WSB A;  4KWD A;  4KFA A;  2E8V A;  1DI1 A;  2AEK A;  1HXG A;  5IN8 A;  1N21 A;  2Z7H A;  1N20 A;  3P8L A;  3LLW A;  5EAU A;  3VJA A;  3N3D A;  2Z4V A;  3NPK A;  4NG6 A;  1HM7 A;  1VG4 A;  2Q9Z A;  4LUU A;  3W7F A;  3ASX A;  4GAX A;  3SDT A;  1RTR A;  3WJO A;  4JXN A;  3OAB B;  3N46 F;  5ILJ A;  3AQ0 A;  3OAC B;  3N6K F;  3APZ A;  5DGS F;  2F8C F;  5E8K A;  3N0F A;  2I19 A;  3MAV A;  4OMH A;  2Z4Y A;  5IKA A;  2Z7I A;  5IKH A;  3WCA A;  3ICM A;  4LLS A;  3P8R A;  3SDU A;  3PKO A;  2Z4W A;  3EZ3 A;  4KK2 A;  2OPM A;  4LPG F;  5DJR F;  4KVW A;  4LTZ A;  3LSN A;  1UBY A;  3IBA A;  2E91 A;  1WKZ A;  2PS7 A;  2F92 F;  3LOM A;  3LGK A;  3KRO A;  1N23 A;  4UMJ A;  5ERN A;  5B03 A;  3EFQ A;  1UBX A;  4MC0 A;  3MZV A;  3LDW A;  1DGP A;  1VG3 A;  3S9V A;  2ZCQ A;  1YYQ A;  5DHK A;  3TFV A;  4RXE A;  1RQI A;  4JZX A;  3M00 A;  1WL0 A;  2ONG A;  3EGT A;  3KBK A;  3WCE A;  2AZL A;  5B0L A;  4DZW A;  4NKF A;  3WCD A;  1HM4 A;  5DZ2 A;  3TC1 A;  2EWG A;  4KPD A;  3M9U A;  3Q1O A;  4QPF A;  4LA5 A;  3UCA A;  4EA1 A;  3WCF A;  4K10 A;  2E4O A;  4JVJ F;  3LGZ B;  4MC8 A;  2PS8 A;  3ACX A;  1YV5 A;  4F6X A;  3ADZ A;  3SAE A;  5JV1 F;  3PYB A;  5DHI A;  4JYX A;  3WCM A;  1HXA A;  1WY0 A;  5AYP A;  3KRP A;  5I1U A;  1KIY A;  2E93 A;  3LJI A;  1N1Z A;  4LZ3 A;  1YJ4 A;  2J5C A;  5IMI A;  1KIZ A;  2FOR A;  5AFX A;  4LFV F;  1WL3 A;  1V4I A;  4LIX A;  3M01 A;  3WJN A;  2J1O A;  3Q2Z A;  5ERM A;  4EA0 A;  4H5E F;  4KQ5 A;  4DEM F;  1YYS A;  4NFI F;  4H5D F;  3TFN A;  3N1W F;  3N3L F;  3WC9 A;  1VG6 A;  4P0W A;  2F7M F;  3WCG A;  4GP2 A;  3AQC B;  4KVY A;  5B0J A;  3CP6 A;  5ILZ A;  4PVX F;  1V4J A;  3P5P A;  3AQB B;  1YYU A; 
#chains in the Genus database with same CATH homology
 3OAB A;  3ICZ A;  4Q23 A;  3N5J F;  2OPN A;  3OAC A;  3WCJ A;  2Z50 A;  1HX9 A;  2ZEV A;  3TS7 A;  1RQJ A;  3TFP A;  4LLT A;  3KRF B;  4LOB A;  4RXD A;  3BNY A;  4LA6 A;  3M02 A;  5ILY A;  1V4E A;  5EAT A;  3PDE A;  3PYA A;  3KRF A;  4F62 A;  5A0I A;  4KKM A;  4NUA A;  3Q2Q A;  4E9U A;  3WCI A;  2ZCS A;  4H5C F;  4XQS F;  4FJQ A;  5A0K A;  5IM1 A;  3RMG A;  3NPR A;  4GA3 A;  4L2X F;  1VG2 A;  4RNQ A;  5IK6 A;  3P41 A;  3DYG A;  4N9U A;  3WCB A;  3S4J A;  3V1X A;  5ILD A;  4RXC A;  5ILK A;  5IK0 A;  5IL8 A;  3WCH A;  3ZCD A;  3ACW A;  4NFJ F;  3G4F A;  3OYR A;  3KRC B;  1EZF A;  5IK9 A;  3ICN A;  5E8L A;  2F94 F;  2F9K F;  3ID0 A;  2E8X A;  4HD1 A;  2E8U A;  3VJ8 A;  5CG6 A;  2Q80 A;  1UBW A;  2Z4Z A;  2O1O A;  1UBV A;  3RBM A;  4KVD A;  4OKZ A;  3V66 A;  2DH4 A;  3SDV A;  3WE9 A;  5JV2 F;  3AE0 A;  1VG7 A;  2P1C A;  3WEF A;  5HN9 A;  1YHM A;  4XQR F;  1N22 A;  5H9D A;  4JZB A;  5DJP F;  5E8H A;  4OMG A;  2PS4 A;  4GP1 A;  1N24 A;  4LTV A;  3WEK A;  3WEI A;  2QIS A;  2Z4X A;  4NKE A;  3RYW A;  2E95 A;  3V1V A;  3LG5 A;  2AET A;  3N45 F;  3QQV A;  5ER8 A;  3LMD A;  5B0K A;  4PVY F;  5ILH A;  5HNA A;  4LPH F;  3LK5 A;  3DYH A;  2PS6 A;  5C05 A;  3KRA B;  2E94 A;  3NRI A;  1N1B A;  5EAS A;  3PH7 A;  1WL2 A;  4XQT F;  4P0X A;  3WEG A;  3KRA A;  4DI5 A;  2H8O A;  5HN8 A;  5B0I A;  2F8Z F;  5JV0 F;  1YHK A;  4E9Z A;  3WEJ A;  4N1Z F;  4LXW A;  5DGN F;  2ONH A;  3N49 F;  4RXA A;  5KSX F;  4NFK F;  3VJ9 A;  5IL3 A;  2VF6 A;  1YHL A;  4KQS A;  4DWG A;  3VJC A;  4LFE A;  3CKE A;  2ZCO A;  5JUZ F;  3ZOU A;  5DW7 A;  4KUX A;  4P0V A;  2OA6 A;  3LEE A;  5DGM F;  2E90 A;  5DIQ F;  2AZJ A;  3NF2 A;  5ILI A;  2E92 A;  3WCL A;  5B00 A;  3WSA A;  4KVI A;  1YQ7 A;  4QXS F;  3LZ9 A;  1YYR A;  1ZW5 A;  4F6V A;  4OKM A;  2RAH A;  1V4H A;  3ZMB A;  3G4D A;  1JFA A;  5ERO A;  3SDQ A;  3ZL6 A;  1WL1 A;  1FPS A;  2AEL A;  1V4K A;  2E8T A;  3B7L A;  3VJD A;  3ZMC A;  4KQU A;  4MC3 A;  3BNX A;  3P5R A;  3IPI A;  3KRO B;  2FTZ A;  3QKC A;  5B0M A;  3DYF A;  3ACY A;  5B02 A;  3LVS A;  3N5H F;  3VJB A;  1JFG A;  4RYP A;  3KRC A;  4EA2 A;  3RYE A;  4DWB A;  2AZK A;  3KB9 A;  4DXJ A;  2ZY1 A;  5IMN A;  3Q30 A;  3SDR A;  2J1P A;  2Z52 A;  2Z78 A;  4LZC A;  3N1V F;  3WEH A;  2ZEU A;  1PS1 A;  5AHU B;  1HXC A;  3VJE A;  2Q9Y A;  4KPJ A;  5JA0 F;  1WMW A;  4ZQ8 A;  2F89 F;  4OGU A;  4DHD A;  3M0G A;  4WK5 A;  3N0G A;  4LFG A;  3WCC A;  5IMP A;  2ZCR A;  3KRP B;  4LZ0 A;  4JXY A;  4E1E A;  1YYT A;  3CC9 A;  5HN7 A;  2OGD A;  2Q58 A;  5A0J A;  5DJV F;  5CG5 A;  3WJK A;  5B01 A;  2PS5 A;  5AEL A;  4FP4 A;  5IVG A;  2E8W A;  3ICK A;  3WSB A;  4KWD A;  4KFA A;  2E8V A;  1DI1 A;  2AEK A;  1HXG A;  5IN8 A;  1N21 A;  2Z7H A;  1N20 A;  3P8L A;  3LLW A;  5EAU A;  3VJA A;  3N3D A;  2Z4V A;  3NPK A;  4NG6 A;  1HM7 A;  1VG4 A;  2Q9Z A;  4LUU A;  3W7F A;  3ASX A;  4GAX A;  3SDT A;  1RTR A;  3WJO A;  4JXN A;  3OAB B;  3N46 F;  5ILJ A;  3AQ0 A;  3OAC B;  3N6K F;  3APZ A;  5DGS F;  2F8C F;  5E8K A;  3N0F A;  2I19 A;  3MAV A;  4OMH A;  2Z4Y A;  5IKA A;  2Z7I A;  5IKH A;  3WCA A;  3ICM A;  4LLS A;  3P8R A;  3SDU A;  3PKO A;  2Z4W A;  3EZ3 A;  4KK2 A;  2OPM A;  4LPG F;  5DJR F;  4KVW A;  4LTZ A;  3LSN A;  1UBY A;  3IBA A;  2E91 A;  1WKZ A;  2PS7 A;  2F92 F;  3LOM A;  3LGK A;  3KRO A;  1N23 A;  4UMJ A;  5ERN A;  5B03 A;  3EFQ A;  1UBX A;  4MC0 A;  3MZV A;  3LDW A;  1DGP A;  1VG3 A;  3S9V A;  2ZCQ A;  1YYQ A;  5DHK A;  3TFV A;  4RXE A;  1RQI A;  4JZX A;  3M00 A;  1WL0 A;  2ONG A;  3EGT A;  3KBK A;  3WCE A;  2AZL A;  5B0L A;  4DZW A;  4NKF A;  3WCD A;  1HM4 A;  5DZ2 A;  3TC1 A;  2EWG A;  4KPD A;  3M9U A;  3Q1O A;  4QPF A;  4LA5 A;  3UCA A;  4EA1 A;  3WCF A;  4K10 A;  2E4O A;  4JVJ F;  3LGZ B;  4MC8 A;  2PS8 A;  3ACX A;  1YV5 A;  4F6X A;  3ADZ A;  3SAE A;  5JV1 F;  3PYB A;  5DHI A;  4JYX A;  3WCM A;  1HXA A;  1WY0 A;  5AYP A;  3KRP A;  5I1U A;  1KIY A;  2E93 A;  3LJI A;  1N1Z A;  4LZ3 A;  1YJ4 A;  2J5C A;  5IMI A;  1KIZ A;  2FOR A;  5AFX A;  4LFV F;  1WL3 A;  1V4I A;  4LIX A;  3M01 A;  3WJN A;  2J1O A;  3Q2Z A;  5ERM A;  4EA0 A;  4H5E F;  4KQ5 A;  4DEM F;  1YYS A;  4NFI F;  4H5D F;  3TFN A;  3N1W F;  3N3L F;  3WC9 A;  1VG6 A;  4P0W A;  2F7M F;  3WCG A;  4GP2 A;  3AQC B;  4KVY A;  5B0J A;  3CP6 A;  5ILZ A;  4PVX F;  1V4J A;  3P5P A;  3AQB B;  1YYU A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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