3ICNA

Trypanosoma cruzi farnesyl diphosphate synthase homodimer in complex with isopentenyl pyrophosphate and 3-fluoro-1-(2-hydroxy-2,2-bis-phosphono-ethyl)-pyridinium
Total Genus 148
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
148
sequence length
362
structure length
362
Chain Sequence
MASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYFRGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDIMDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLKDLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIYKRIVKYKTTFYTYLLPLVMGLFVSEAAASVEMNLVERVAHLIGEYFQVQDDVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGDKDPAKVAVVKRLYSEANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESVAVVWEKTHKRKK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer.
pubmed doi rcsb
molecule keywords Farnesyl pyrophosphate synthase
molecule tags Transferase
source organism Trypanosoma cruzi
total genus 148
structure length 362
sequence length 362
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2009-07-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3icnA00
3LLWA 5DHKA 4PVXF 1UBVA 4EA1A 1N24A 1RQIA 3WC9A 3KROA 4H5EF 4KWDA 3V66A 1HX9A 5B0IA 4RNQA 2Q80A 1UBYA 2ZEUA 3EGTA 5AYPA 2E93A 3S9VA 5I1UA 5IK6A 3VJDA 1HXAA 3OACA 3DYHA 1WY0A 4WK5A 4LZCA 3RMGA 5IL3A 1YHLA 1YJ4A 3ACWA 4OKMA 4E9ZA 1YYTA 3OABB 1N20A 4JYXA 2F9KF 4XQRF 5B0KA 3M00A 3N1WF 1V4HA 3Q30A 3VJCA 3WJNA 3Q2ZA 5ILIA 3LMDA 4KVIA 3RYEA 3ACYA 2DH4A 3PDEA 4MC8A 4NFKF 2Z4XA 1N22A 3LZ9A 3B7LA 4HD1A 2AZKA 4KFAA 4E1EA 3WCJA 4LA5A 2PS6A 3ZL6A 3P41A 1YV5A 4UMJA 4LPGF 3AQBB 4XQSF 2PS4A 5DIQF 2AEKA 4NUAA 2F7MF 4KUXA 5E8HA 4RXAA 1WMWA 2QISA 2E8TA 2E95A 3WCEA 3RYWA 4DWGA 4XQTF 1ZW5A 2F8CF 2Z4YA 4JXYA 1DGPA 4NFJF 2AZLA 2ZCRA 5ERNA 2E91A 1HM7A 4L2XF 2J1OA 3BNXA 4KPDA 4KPJA 3KB9A 5C05A 4F62A 4H5DF 5B0LA 3WJOA 3SDTA 1V4KA 2E94A 4LOBA 3VJEA 4LIXA 4DI5A 3LGKA 5ER8A 3OACB 5IK0A 1RTRA 3SAEA 5IKHA 2ZEVA 2H8OA 1VG2A 2I19A 5IM1A 5HNAA 4LFVF 2PS5A 3QKCA 1V4IA 1V4EA 2Z4WA 1UBXA 2E8VA 3BNYA 1YQ7A 1N1ZA 2F8ZF 3AQCB 3SDRA 3Q2QA 3ICKA 3KRAA 3N3DA 4OGUA 5ILYA 1JFAA 4KQUA 5DJPF 3WEJA 4RXDA 3ACXA 3M0GA 2ONHA 4GP2A 2E92A 5CG5A 4KQSA 1WL3A 2F94F 3W7FA 1UBWA 2VF6A 3KBKA 4KKMA 5B0MA 3MAVA 3NPKA 4OKZA 4PVYF 5B02A 4Q23A 5AFXA 5EROA 1VG6A 1KIYA 5AHUB 3WEFA 3VJBA 5JA0F 2Z4VA 4NKEA 4LTZA 3WEKA 1WKZA 2Q58A 3M9UA 5B0JA 3WEHA 4DEMF 5A0IA 5H9DA 3G4DA 3P8RA 4LA6A 3ICMA 5ILDA 5DZ2A 4P0WA 3PKOA 3ID0A 3LJIA 4LLSA 3N45F 3DYGA 3M01A 5KSXF 3N46F 3WSAA 1RQJA 3WCLA 3AQ0A 3IBAA 3WCCA 3LOMA 3WCAA 3KRAB 2AELA 4LZ3A 2Q9YA 3NRIA 2FORA 2E8XA 5CG6A 3CP6A 4EA2A 2F92F 4MC3A 5EAUA 3N3LF 1N23A 2FTZA 3SDUA 2E8WA 4E9UA 1YHMA 3ICZA 4LTVA 5E8LA 4ZQ8A 5ILJA 5ILKA 3N49F 3ZMBA 1HXCA 2ZCSA 5DGNF 3TFNA 2O1OA 4DHDA 5IMNA 5IMIA 4FJQA 4DXJA 3CKEA 5HN9A 1YYSA 5ILZA 1VG3A 4QPFA 3TFPA 3OYRA 2Z4ZA 3LEEA 4LLTA 4LPHF 3ASXA 3ZCDA 4JVJF 2J1PA 5IMPA 3KRCB 1VG7A 4EA0A 2Z78A 3ICNA 4QXSF 4RXEA 5EASA 3VJ9A 3LVSA 2RAHA 4F6VA 3AE0A 2AETA 3WSBA 5JV1F 1PS1A 3LGZB 4JZXA 5EATA 1YYUA 2Z52A 2E4OA 4GA3A 4JZBA 4DZWA 3WEGA 4KVWA 3V1VA 4F6XA 4K10A 1JFGA 3QQVA 3ADZA 1WL0A 4NKFA 4P0XA 5DJVF 3LDWA 3PH7A 4RYPA 2E90A 1FPSA 3P8LA 2OPMA 3IPIA 2EWGA 2PS8A 5ERMA 3EZ3A 3S4JA 5DW7A 1DI1A 3KRCA 5IVGA 3N0GA 5IKAA 3PYBA 3KRFA 3ZMCA 1N1BA 1WL2A 5B00A 1EZFA 5B01A 3VJ8A 1YYQA 4LUUA 4P0VA 3CC9A 3NF2A 4KVYA 3WE9A 1WL1A 3MZVA 4LFEA 3RBMA 3WCGA 3Q1OA 3LSNA 2Q9ZA 5A0JA 5JV2F 3N6KF 5DJRF 2OPNA 3N5JF 4NFIF 3WCHA 3EFQA 5HN8A 3G4FA 3M02A 3KRPA 3P5RA 2OA6A 4JXNA 5IN8A 3N1VF 4OMGA 3SDQA 4GP1A 3WCBA 5E8KA 2ZY1A 1HXGA 3DYFA 4GAXA 4LZ0A 5B03A 2Z7IA 4LFGA 5HN7A 4NG6A 5JV0F 3VJAA 3TC1A 3TS7A 2PS7A 3PYAA 3APZA 3WCMA 3N5HF 4N9UA 5JUZF 4OMHA 3N0FA 2J5CA 3V1XA 2ZCQA 3ZOUA 3KROB 2AZJA 1YYRA 3KRFB 2Z50A 4KVDA 1KIZA 3WJKA 2P1CA 1VG4A 2Z7HA 3UCAA 2OGDA 2F89F 1YHKA 3OABA 5DGMF 5DGSF 3NPRA 4FP4A 3P5PA 5DHIA 5AELA 3WCDA 5IL8A 2ONGA 4N1ZF 4KK2A 1HM4A 4KQ5A 4LXWA 5IK9A 4RXCA 3WCIA 3KRPB 1V4JA 1N21A 4H5CF 2ZCOA 3SDVA 4DWBA 3WEIA 3WCFA 3TFVA 3LG5A 5A0KA 2E8UA 4MC0A 3LK5A 5ILHA
chains in the Genus database with same CATH superfamily
3LLWA 5DHKA 4PVXF 1UBVA 4EA1A 1N24A 1RQIA 3WC9A 3KROA 4H5EF 4KWDA 3V66A 1HX9A 5B0IA 4RNQA 2Q80A 1UBYA 2ZEUA 3EGTA 5AYPA 2E93A 3S9VA 5I1UA 5IK6A 3VJDA 1HXAA 3OACA 3DYHA 1WY0A 4WK5A 4LZCA 3RMGA 5IL3A 1YHLA 1YJ4A 3ACWA 4OKMA 4E9ZA 1YYTA 3OABB 1N20A 4JYXA 2F9KF 4XQRF 5B0KA 3M00A 3N1WF 1V4HA 3Q30A 3VJCA 3WJNA 3Q2ZA 5ILIA 3LMDA 4KVIA 3RYEA 3ACYA 2DH4A 3PDEA 4MC8A 4NFKF 2Z4XA 1N22A 3LZ9A 3B7LA 4HD1A 2AZKA 4KFAA 4E1EA 3WCJA 4LA5A 2PS6A 3ZL6A 3P41A 1YV5A 4UMJA 4LPGF 3AQBB 4XQSF 2PS4A 5DIQF 2AEKA 4NUAA 2F7MF 4KUXA 5E8HA 4RXAA 1WMWA 2QISA 2E8TA 2E95A 3WCEA 3RYWA 4DWGA 4XQTF 1ZW5A 2F8CF 2Z4YA 4JXYA 1DGPA 4NFJF 2AZLA 2ZCRA 5ERNA 2E91A 1HM7A 4L2XF 2J1OA 3BNXA 4KPDA 4KPJA 3KB9A 5C05A 4F62A 4H5DF 5B0LA 3WJOA 3SDTA 1V4KA 2E94A 4LOBA 3VJEA 4LIXA 4DI5A 3LGKA 5ER8A 3OACB 5IK0A 1RTRA 3SAEA 5IKHA 2ZEVA 2H8OA 1VG2A 2I19A 5IM1A 5HNAA 4LFVF 2PS5A 3QKCA 1V4IA 1V4EA 2Z4WA 1UBXA 2E8VA 3BNYA 1YQ7A 1N1ZA 2F8ZF 3AQCB 3SDRA 3Q2QA 3ICKA 3KRAA 3N3DA 4OGUA 5ILYA 1JFAA 4KQUA 5DJPF 3WEJA 4RXDA 3ACXA 3M0GA 2ONHA 4GP2A 2E92A 5CG5A 4KQSA 1WL3A 2F94F 3W7FA 1UBWA 2VF6A 3KBKA 4KKMA 5B0MA 3MAVA 3NPKA 4OKZA 4PVYF 5B02A 4Q23A 5AFXA 5EROA 1VG6A 1KIYA 5AHUB 3WEFA 3VJBA 5JA0F 2Z4VA 4NKEA 4LTZA 3WEKA 1WKZA 2Q58A 3M9UA 5B0JA 3WEHA 4DEMF 5A0IA 5H9DA 3G4DA 3P8RA 4LA6A 3ICMA 5ILDA 5DZ2A 4P0WA 3PKOA 3ID0A 3LJIA 4LLSA 3N45F 3DYGA 3M01A 5KSXF 3N46F 3WSAA 1RQJA 3WCLA 3AQ0A 3IBAA 3WCCA 3LOMA 3WCAA 3KRAB 2AELA 4LZ3A 2Q9YA 3NRIA 2FORA 2E8XA 5CG6A 3CP6A 4EA2A 2F92F 4MC3A 5EAUA 3N3LF 1N23A 2FTZA 3SDUA 2E8WA 4E9UA 1YHMA 3ICZA 4LTVA 5E8LA 4ZQ8A 5ILJA 5ILKA 3N49F 3ZMBA 1HXCA 2ZCSA 5DGNF 3TFNA 2O1OA 4DHDA 5IMNA 5IMIA 4FJQA 4DXJA 3CKEA 5HN9A 1YYSA 5ILZA 1VG3A 4QPFA 3TFPA 3OYRA 2Z4ZA 3LEEA 4LLTA 4LPHF 3ASXA 3ZCDA 4JVJF 2J1PA 5IMPA 3KRCB 1VG7A 4EA0A 2Z78A 3ICNA 4QXSF 4RXEA 5EASA 3VJ9A 3LVSA 2RAHA 4F6VA 3AE0A 2AETA 3WSBA 5JV1F 1PS1A 3LGZB 4JZXA 5EATA 1YYUA 2Z52A 2E4OA 4GA3A 4JZBA 4DZWA 3WEGA 4KVWA 3V1VA 4F6XA 4K10A 1JFGA 3QQVA 3ADZA 1WL0A 4NKFA 4P0XA 5DJVF 3LDWA 3PH7A 4RYPA 2E90A 1FPSA 3P8LA 2OPMA 3IPIA 2EWGA 2PS8A 5ERMA 3EZ3A 3S4JA 5DW7A 1DI1A 3KRCA 5IVGA 3N0GA 5IKAA 3PYBA 3KRFA 3ZMCA 1N1BA 1WL2A 5B00A 1EZFA 5B01A 3VJ8A 1YYQA 4LUUA 4P0VA 3CC9A 3NF2A 4KVYA 3WE9A 1WL1A 3MZVA 4LFEA 3RBMA 3WCGA 3Q1OA 3LSNA 2Q9ZA 5A0JA 5JV2F 3N6KF 5DJRF 2OPNA 3N5JF 4NFIF 3WCHA 3EFQA 5HN8A 3G4FA 3M02A 3KRPA 3P5RA 2OA6A 4JXNA 5IN8A 3N1VF 4OMGA 3SDQA 4GP1A 3WCBA 5E8KA 2ZY1A 1HXGA 3DYFA 4GAXA 4LZ0A 5B03A 2Z7IA 4LFGA 5HN7A 4NG6A 5JV0F 3VJAA 3TC1A 3TS7A 2PS7A 3PYAA 3APZA 3WCMA 3N5HF 4N9UA 5JUZF 4OMHA 3N0FA 2J5CA 3V1XA 2ZCQA 3ZOUA 3KROB 2AZJA 1YYRA 3KRFB 2Z50A 4KVDA 1KIZA 3WJKA 2P1CA 1VG4A 2Z7HA 3UCAA 2OGDA 2F89F 1YHKA 3OABA 5DGMF 5DGSF 3NPRA 4FP4A 3P5PA 5DHIA 5AELA 3WCDA 5IL8A 2ONGA 4N1ZF 4KK2A 1HM4A 4KQ5A 4LXWA 5IK9A 4RXCA 3WCIA 3KRPB 1V4JA 1N21A 4H5CF 2ZCOA 3SDVA 4DWBA 3WEIA 3WCFA 3TFVA 3LG5A 5A0KA 2E8UA 4MC0A 3LK5A 5ILHA
chains in the Genus database with same CATH topology
3LLWA 5DHKA 4PVXF 1UBVA 4EA1A 1N24A 1RQIA 3WC9A 3KROA 4H5EF 4KWDA 3V66A 1HX9A 5B0IA 4RNQA 2Q80A 1UBYA 2ZEUA 3EGTA 5AYPA 2E93A 3S9VA 5I1UA 5IK6A 3VJDA 1HXAA 3OACA 3DYHA 1WY0A 4WK5A 4LZCA 3RMGA 5IL3A 1YHLA 1YJ4A 3ACWA 4OKMA 4E9ZA 1YYTA 3OABB 1N20A 4JYXA 2F9KF 4XQRF 5B0KA 3M00A 3N1WF 1V4HA 3Q30A 3VJCA 3WJNA 3Q2ZA 5ILIA 3LMDA 4KVIA 3RYEA 3ACYA 2DH4A 3PDEA 4MC8A 4NFKF 2Z4XA 1N22A 3LZ9A 3B7LA 4HD1A 2AZKA 4KFAA 4E1EA 3WCJA 4LA5A 2PS6A 3ZL6A 3P41A 1YV5A 4UMJA 4LPGF 3AQBB 4XQSF 2PS4A 5DIQF 2AEKA 4NUAA 2F7MF 4KUXA 5E8HA 4RXAA 1WMWA 2QISA 2E8TA 2E95A 3WCEA 3RYWA 4DWGA 4XQTF 1ZW5A 2F8CF 2Z4YA 4JXYA 1DGPA 4NFJF 2AZLA 2ZCRA 5ERNA 2E91A 1HM7A 4L2XF 2J1OA 3BNXA 4KPDA 4KPJA 3KB9A 5C05A 4F62A 4H5DF 5B0LA 3WJOA 3SDTA 1V4KA 2E94A 4LOBA 3VJEA 4LIXA 4DI5A 3LGKA 5ER8A 3OACB 5IK0A 1RTRA 3SAEA 5IKHA 2ZEVA 2H8OA 1VG2A 2I19A 5IM1A 5HNAA 4LFVF 2PS5A 3QKCA 1V4IA 1V4EA 2Z4WA 1UBXA 2E8VA 3BNYA 1YQ7A 1N1ZA 2F8ZF 3AQCB 3SDRA 3Q2QA 3ICKA 3KRAA 3N3DA 4OGUA 5ILYA 1JFAA 4KQUA 5DJPF 3WEJA 4RXDA 3ACXA 3M0GA 2ONHA 4GP2A 2E92A 5CG5A 4KQSA 1WL3A 2F94F 3W7FA 1UBWA 2VF6A 3KBKA 4KKMA 5B0MA 3MAVA 3NPKA 4OKZA 4PVYF 5B02A 4Q23A 5AFXA 5EROA 1VG6A 1KIYA 5AHUB 3WEFA 3VJBA 5JA0F 2Z4VA 4NKEA 4LTZA 3WEKA 1WKZA 2Q58A 3M9UA 5B0JA 3WEHA 4DEMF 5A0IA 5H9DA 3G4DA 3P8RA 4LA6A 3ICMA 5ILDA 5DZ2A 4P0WA 3PKOA 3ID0A 3LJIA 4LLSA 3N45F 3DYGA 3M01A 5KSXF 3N46F 3WSAA 1RQJA 3WCLA 3AQ0A 3IBAA 3WCCA 3LOMA 3WCAA 3KRAB 2AELA 4LZ3A 2Q9YA 3NRIA 2FORA 2E8XA 5CG6A 3CP6A 4EA2A 2F92F 4MC3A 5EAUA 3N3LF 1N23A 2FTZA 3SDUA 2E8WA 4E9UA 1YHMA 3ICZA 4LTVA 5E8LA 4ZQ8A 5ILJA 5ILKA 3N49F 3ZMBA 1HXCA 2ZCSA 5DGNF 3TFNA 2O1OA 4DHDA 5IMNA 5IMIA 4FJQA 4DXJA 3CKEA 5HN9A 1YYSA 5ILZA 1VG3A 4QPFA 3TFPA 3OYRA 2Z4ZA 3LEEA 4LLTA 4LPHF 3ASXA 3ZCDA 4JVJF 2J1PA 5IMPA 3KRCB 1VG7A 4EA0A 2Z78A 3ICNA 4QXSF 4RXEA 5EASA 3VJ9A 3LVSA 2RAHA 4F6VA 3AE0A 2AETA 3WSBA 5JV1F 1PS1A 3LGZB 4JZXA 5EATA 1YYUA 2Z52A 2E4OA 4GA3A 4JZBA 4DZWA 3WEGA 4KVWA 3V1VA 4F6XA 4K10A 1JFGA 3QQVA 3ADZA 1WL0A 4NKFA 4P0XA 5DJVF 3LDWA 3PH7A 4RYPA 2E90A 1FPSA 3P8LA 2OPMA 3IPIA 2EWGA 2PS8A 5ERMA 3EZ3A 3S4JA 5DW7A 1DI1A 3KRCA 5IVGA 3N0GA 5IKAA 3PYBA 3KRFA 3ZMCA 1N1BA 1WL2A 5B00A 1EZFA 5B01A 3VJ8A 1YYQA 4LUUA 4P0VA 3CC9A 3NF2A 4KVYA 3WE9A 1WL1A 3MZVA 4LFEA 3RBMA 3WCGA 3Q1OA 3LSNA 2Q9ZA 5A0JA 5JV2F 3N6KF 5DJRF 2OPNA 3N5JF 4NFIF 3WCHA 3EFQA 5HN8A 3G4FA 3M02A 3KRPA 3P5RA 2OA6A 4JXNA 5IN8A 3N1VF 4OMGA 3SDQA 4GP1A 3WCBA 5E8KA 2ZY1A 1HXGA 3DYFA 4GAXA 4LZ0A 5B03A 2Z7IA 4LFGA 5HN7A 4NG6A 5JV0F 3VJAA 3TC1A 3TS7A 2PS7A 3PYAA 3APZA 3WCMA 3N5HF 4N9UA 5JUZF 4OMHA 3N0FA 2J5CA 3V1XA 2ZCQA 3ZOUA 3KROB 2AZJA 1YYRA 3KRFB 2Z50A 4KVDA 1KIZA 3WJKA 2P1CA 1VG4A 2Z7HA 3UCAA 2OGDA 2F89F 1YHKA 3OABA 5DGMF 5DGSF 3NPRA 4FP4A 3P5PA 5DHIA 5AELA 3WCDA 5IL8A 2ONGA 4N1ZF 4KK2A 1HM4A 4KQ5A 4LXWA 5IK9A 4RXCA 3WCIA 3KRPB 1V4JA 1N21A 4H5CF 2ZCOA 3SDVA 4DWBA 3WEIA 3WCFA 3TFVA 3LG5A 5A0KA 2E8UA 4MC0A 3LK5A 5ILHA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3LLW A;  5DHK A;  4PVX F;  1UBV A;  4EA1 A;  1N24 A;  1RQI A;  3WC9 A;  3KRO A;  4H5E F;  4KWD A;  3V66 A;  1HX9 A;  5B0I A;  4RNQ A;  2Q80 A;  1UBY A;  2ZEU A;  3EGT A;  5AYP A;  2E93 A;  3S9V A;  5I1U A;  5IK6 A;  3VJD A;  1HXA A;  3OAC A;  3DYH A;  1WY0 A;  4WK5 A;  4LZC A;  3RMG A;  5IL3 A;  1YHL A;  1YJ4 A;  3ACW A;  4OKM A;  4E9Z A;  1YYT A;  3OAB B;  1N20 A;  4JYX A;  2F9K F;  4XQR F;  5B0K A;  3M00 A;  3N1W F;  1V4H A;  3Q30 A;  3VJC A;  3WJN A;  3Q2Z A;  5ILI A;  3LMD A;  4KVI A;  3RYE A;  3ACY A;  2DH4 A;  3PDE A;  4MC8 A;  4NFK F;  2Z4X A;  1N22 A;  3LZ9 A;  3B7L A;  4HD1 A;  2AZK A;  4KFA A;  4E1E A;  3WCJ A;  4LA5 A;  2PS6 A;  3ZL6 A;  3P41 A;  1YV5 A;  4UMJ A;  4LPG F;  3AQB B;  4XQS F;  2PS4 A;  5DIQ F;  2AEK A;  4NUA A;  2F7M F;  4KUX A;  5E8H A;  4RXA A;  1WMW A;  2QIS A;  2E8T A;  2E95 A;  3WCE A;  3RYW A;  4DWG A;  4XQT F;  1ZW5 A;  2F8C F;  2Z4Y A;  4JXY A;  1DGP A;  4NFJ F;  2AZL A;  2ZCR A;  5ERN A;  2E91 A;  1HM7 A;  4L2X F;  2J1O A;  3BNX A;  4KPD A;  4KPJ A;  3KB9 A;  5C05 A;  4F62 A;  4H5D F;  5B0L A;  3WJO A;  3SDT A;  1V4K A;  2E94 A;  4LOB A;  3VJE A;  4LIX A;  4DI5 A;  3LGK A;  5ER8 A;  3OAC B;  5IK0 A;  1RTR A;  3SAE A;  5IKH A;  2ZEV A;  2H8O A;  1VG2 A;  2I19 A;  5IM1 A;  5HNA A;  4LFV F;  2PS5 A;  3QKC A;  1V4I A;  1V4E A;  2Z4W A;  1UBX A;  2E8V A;  3BNY A;  1YQ7 A;  1N1Z A;  2F8Z F;  3AQC B;  3SDR A;  3Q2Q A;  3ICK A;  3KRA A;  3N3D A;  4OGU A;  5ILY A;  1JFA A;  4KQU A;  5DJP F;  3WEJ A;  4RXD A;  3ACX A;  3M0G A;  2ONH A;  4GP2 A;  2E92 A;  5CG5 A;  4KQS A;  1WL3 A;  2F94 F;  3W7F A;  1UBW A;  2VF6 A;  3KBK A;  4KKM A;  5B0M A;  3MAV A;  3NPK A;  4OKZ A;  4PVY F;  5B02 A;  4Q23 A;  5AFX A;  5ERO A;  1VG6 A;  1KIY A;  5AHU B;  3WEF A;  3VJB A;  5JA0 F;  2Z4V A;  4NKE A;  4LTZ A;  3WEK A;  1WKZ A;  2Q58 A;  3M9U A;  5B0J A;  3WEH A;  4DEM F;  5A0I A;  5H9D A;  3G4D A;  3P8R A;  4LA6 A;  3ICM A;  5ILD A;  5DZ2 A;  4P0W A;  3PKO A;  3ID0 A;  3LJI A;  4LLS A;  3N45 F;  3DYG A;  3M01 A;  5KSX F;  3N46 F;  3WSA A;  1RQJ A;  3WCL A;  3AQ0 A;  3IBA A;  3WCC A;  3LOM A;  3WCA A;  3KRA B;  2AEL A;  4LZ3 A;  2Q9Y A;  3NRI A;  2FOR A;  2E8X A;  5CG6 A;  3CP6 A;  4EA2 A;  2F92 F;  4MC3 A;  5EAU A;  3N3L F;  1N23 A;  2FTZ A;  3SDU A;  2E8W A;  4E9U A;  1YHM A;  3ICZ A;  4LTV A;  5E8L A;  4ZQ8 A;  5ILJ A;  5ILK A;  3N49 F;  3ZMB A;  1HXC A;  2ZCS A;  5DGN F;  3TFN A;  2O1O A;  4DHD A;  5IMN A;  5IMI A;  4FJQ A;  4DXJ A;  3CKE A;  5HN9 A;  1YYS A;  5ILZ A;  1VG3 A;  4QPF A;  3TFP A;  3OYR A;  2Z4Z A;  3LEE A;  4LLT A;  4LPH F;  3ASX A;  3ZCD A;  4JVJ F;  2J1P A;  5IMP A;  3KRC B;  1VG7 A;  4EA0 A;  2Z78 A;  3ICN A;  4QXS F;  4RXE A;  5EAS A;  3VJ9 A;  3LVS A;  2RAH A;  4F6V A;  3AE0 A;  2AET A;  3WSB A;  5JV1 F;  1PS1 A;  3LGZ B;  4JZX A;  5EAT A;  1YYU A;  2Z52 A;  2E4O A;  4GA3 A;  4JZB A;  4DZW A;  3WEG A;  4KVW A;  3V1V A;  4F6X A;  4K10 A;  1JFG A;  3QQV A;  3ADZ A;  1WL0 A;  4NKF A;  4P0X A;  5DJV F;  3LDW A;  3PH7 A;  4RYP A;  2E90 A;  1FPS A;  3P8L A;  2OPM A;  3IPI A;  2EWG A;  2PS8 A;  5ERM A;  3EZ3 A;  3S4J A;  5DW7 A;  1DI1 A;  3KRC A;  5IVG A;  3N0G A;  5IKA A;  3PYB A;  3KRF A;  3ZMC A;  1N1B A;  1WL2 A;  5B00 A;  1EZF A;  5B01 A;  3VJ8 A;  1YYQ A;  4LUU A;  4P0V A;  3CC9 A;  3NF2 A;  4KVY A;  3WE9 A;  1WL1 A;  3MZV A;  4LFE A;  3RBM A;  3WCG A;  3Q1O A;  3LSN A;  2Q9Z A;  5A0J A;  5JV2 F;  3N6K F;  5DJR F;  2OPN A;  3N5J F;  4NFI F;  3WCH A;  3EFQ A;  5HN8 A;  3G4F A;  3M02 A;  3KRP A;  3P5R A;  2OA6 A;  4JXN A;  5IN8 A;  3N1V F;  4OMG A;  3SDQ A;  4GP1 A;  3WCB A;  5E8K A;  2ZY1 A;  1HXG A;  3DYF A;  4GAX A;  4LZ0 A;  5B03 A;  2Z7I A;  4LFG A;  5HN7 A;  4NG6 A;  5JV0 F;  3VJA A;  3TC1 A;  3TS7 A;  2PS7 A;  3PYA A;  3APZ A;  3WCM A;  3N5H F;  4N9U A;  5JUZ F;  4OMH A;  3N0F A;  2J5C A;  3V1X A;  2ZCQ A;  3ZOU A;  3KRO B;  2AZJ A;  1YYR A;  3KRF B;  2Z50 A;  4KVD A;  1KIZ A;  3WJK A;  2P1C A;  1VG4 A;  2Z7H A;  3UCA A;  2OGD A;  2F89 F;  1YHK A;  3OAB A;  5DGM F;  5DGS F;  3NPR A;  4FP4 A;  3P5P A;  5DHI A;  5AEL A;  3WCD A;  5IL8 A;  2ONG A;  4N1Z F;  4KK2 A;  1HM4 A;  4KQ5 A;  4LXW A;  5IK9 A;  4RXC A;  3WCI A;  3KRP B;  1V4J A;  1N21 A;  4H5C F;  2ZCO A;  3SDV A;  4DWB A;  3WEI A;  3WCF A;  3TFV A;  3LG5 A;  5A0K A;  2E8U A;  4MC0 A;  3LK5 A;  5ILH A; 
#chains in the Genus database with same CATH topology
 3LLW A;  5DHK A;  4PVX F;  1UBV A;  4EA1 A;  1N24 A;  1RQI A;  3WC9 A;  3KRO A;  4H5E F;  4KWD A;  3V66 A;  1HX9 A;  5B0I A;  4RNQ A;  2Q80 A;  1UBY A;  2ZEU A;  3EGT A;  5AYP A;  2E93 A;  3S9V A;  5I1U A;  5IK6 A;  3VJD A;  1HXA A;  3OAC A;  3DYH A;  1WY0 A;  4WK5 A;  4LZC A;  3RMG A;  5IL3 A;  1YHL A;  1YJ4 A;  3ACW A;  4OKM A;  4E9Z A;  1YYT A;  3OAB B;  1N20 A;  4JYX A;  2F9K F;  4XQR F;  5B0K A;  3M00 A;  3N1W F;  1V4H A;  3Q30 A;  3VJC A;  3WJN A;  3Q2Z A;  5ILI A;  3LMD A;  4KVI A;  3RYE A;  3ACY A;  2DH4 A;  3PDE A;  4MC8 A;  4NFK F;  2Z4X A;  1N22 A;  3LZ9 A;  3B7L A;  4HD1 A;  2AZK A;  4KFA A;  4E1E A;  3WCJ A;  4LA5 A;  2PS6 A;  3ZL6 A;  3P41 A;  1YV5 A;  4UMJ A;  4LPG F;  3AQB B;  4XQS F;  2PS4 A;  5DIQ F;  2AEK A;  4NUA A;  2F7M F;  4KUX A;  5E8H A;  4RXA A;  1WMW A;  2QIS A;  2E8T A;  2E95 A;  3WCE A;  3RYW A;  4DWG A;  4XQT F;  1ZW5 A;  2F8C F;  2Z4Y A;  4JXY A;  1DGP A;  4NFJ F;  2AZL A;  2ZCR A;  5ERN A;  2E91 A;  1HM7 A;  4L2X F;  2J1O A;  3BNX A;  4KPD A;  4KPJ A;  3KB9 A;  5C05 A;  4F62 A;  4H5D F;  5B0L A;  3WJO A;  3SDT A;  1V4K A;  2E94 A;  4LOB A;  3VJE A;  4LIX A;  4DI5 A;  3LGK A;  5ER8 A;  3OAC B;  5IK0 A;  1RTR A;  3SAE A;  5IKH A;  2ZEV A;  2H8O A;  1VG2 A;  2I19 A;  5IM1 A;  5HNA A;  4LFV F;  2PS5 A;  3QKC A;  1V4I A;  1V4E A;  2Z4W A;  1UBX A;  2E8V A;  3BNY A;  1YQ7 A;  1N1Z A;  2F8Z F;  3AQC B;  3SDR A;  3Q2Q A;  3ICK A;  3KRA A;  3N3D A;  4OGU A;  5ILY A;  1JFA A;  4KQU A;  5DJP F;  3WEJ A;  4RXD A;  3ACX A;  3M0G A;  2ONH A;  4GP2 A;  2E92 A;  5CG5 A;  4KQS A;  1WL3 A;  2F94 F;  3W7F A;  1UBW A;  2VF6 A;  3KBK A;  4KKM A;  5B0M A;  3MAV A;  3NPK A;  4OKZ A;  4PVY F;  5B02 A;  4Q23 A;  5AFX A;  5ERO A;  1VG6 A;  1KIY A;  5AHU B;  3WEF A;  3VJB A;  5JA0 F;  2Z4V A;  4NKE A;  4LTZ A;  3WEK A;  1WKZ A;  2Q58 A;  3M9U A;  5B0J A;  3WEH A;  4DEM F;  5A0I A;  5H9D A;  3G4D A;  3P8R A;  4LA6 A;  3ICM A;  5ILD A;  5DZ2 A;  4P0W A;  3PKO A;  3ID0 A;  3LJI A;  4LLS A;  3N45 F;  3DYG A;  3M01 A;  5KSX F;  3N46 F;  3WSA A;  1RQJ A;  3WCL A;  3AQ0 A;  3IBA A;  3WCC A;  3LOM A;  3WCA A;  3KRA B;  2AEL A;  4LZ3 A;  2Q9Y A;  3NRI A;  2FOR A;  2E8X A;  5CG6 A;  3CP6 A;  4EA2 A;  2F92 F;  4MC3 A;  5EAU A;  3N3L F;  1N23 A;  2FTZ A;  3SDU A;  2E8W A;  4E9U A;  1YHM A;  3ICZ A;  4LTV A;  5E8L A;  4ZQ8 A;  5ILJ A;  5ILK A;  3N49 F;  3ZMB A;  1HXC A;  2ZCS A;  5DGN F;  3TFN A;  2O1O A;  4DHD A;  5IMN A;  5IMI A;  4FJQ A;  4DXJ A;  3CKE A;  5HN9 A;  1YYS A;  5ILZ A;  1VG3 A;  4QPF A;  3TFP A;  3OYR A;  2Z4Z A;  3LEE A;  4LLT A;  4LPH F;  3ASX A;  3ZCD A;  4JVJ F;  2J1P A;  5IMP A;  3KRC B;  1VG7 A;  4EA0 A;  2Z78 A;  3ICN A;  4QXS F;  4RXE A;  5EAS A;  3VJ9 A;  3LVS A;  2RAH A;  4F6V A;  3AE0 A;  2AET A;  3WSB A;  5JV1 F;  1PS1 A;  3LGZ B;  4JZX A;  5EAT A;  1YYU A;  2Z52 A;  2E4O A;  4GA3 A;  4JZB A;  4DZW A;  3WEG A;  4KVW A;  3V1V A;  4F6X A;  4K10 A;  1JFG A;  3QQV A;  3ADZ A;  1WL0 A;  4NKF A;  4P0X A;  5DJV F;  3LDW A;  3PH7 A;  4RYP A;  2E90 A;  1FPS A;  3P8L A;  2OPM A;  3IPI A;  2EWG A;  2PS8 A;  5ERM A;  3EZ3 A;  3S4J A;  5DW7 A;  1DI1 A;  3KRC A;  5IVG A;  3N0G A;  5IKA A;  3PYB A;  3KRF A;  3ZMC A;  1N1B A;  1WL2 A;  5B00 A;  1EZF A;  5B01 A;  3VJ8 A;  1YYQ A;  4LUU A;  4P0V A;  3CC9 A;  3NF2 A;  4KVY A;  3WE9 A;  1WL1 A;  3MZV A;  4LFE A;  3RBM A;  3WCG A;  3Q1O A;  3LSN A;  2Q9Z A;  5A0J A;  5JV2 F;  3N6K F;  5DJR F;  2OPN A;  3N5J F;  4NFI F;  3WCH A;  3EFQ A;  5HN8 A;  3G4F A;  3M02 A;  3KRP A;  3P5R A;  2OA6 A;  4JXN A;  5IN8 A;  3N1V F;  4OMG A;  3SDQ A;  4GP1 A;  3WCB A;  5E8K A;  2ZY1 A;  1HXG A;  3DYF A;  4GAX A;  4LZ0 A;  5B03 A;  2Z7I A;  4LFG A;  5HN7 A;  4NG6 A;  5JV0 F;  3VJA A;  3TC1 A;  3TS7 A;  2PS7 A;  3PYA A;  3APZ A;  3WCM A;  3N5H F;  4N9U A;  5JUZ F;  4OMH A;  3N0F A;  2J5C A;  3V1X A;  2ZCQ A;  3ZOU A;  3KRO B;  2AZJ A;  1YYR A;  3KRF B;  2Z50 A;  4KVD A;  1KIZ A;  3WJK A;  2P1C A;  1VG4 A;  2Z7H A;  3UCA A;  2OGD A;  2F89 F;  1YHK A;  3OAB A;  5DGM F;  5DGS F;  3NPR A;  4FP4 A;  3P5P A;  5DHI A;  5AEL A;  3WCD A;  5IL8 A;  2ONG A;  4N1Z F;  4KK2 A;  1HM4 A;  4KQ5 A;  4LXW A;  5IK9 A;  4RXC A;  3WCI A;  3KRP B;  1V4J A;  1N21 A;  4H5C F;  2ZCO A;  3SDV A;  4DWB A;  3WEI A;  3WCF A;  3TFV A;  3LG5 A;  5A0K A;  2E8U A;  4MC0 A;  3LK5 A;  5ILH A; 
#chains in the Genus database with same CATH homology
 3LLW A;  5DHK A;  4PVX F;  1UBV A;  4EA1 A;  1N24 A;  1RQI A;  3WC9 A;  3KRO A;  4H5E F;  4KWD A;  3V66 A;  1HX9 A;  5B0I A;  4RNQ A;  2Q80 A;  1UBY A;  2ZEU A;  3EGT A;  5AYP A;  2E93 A;  3S9V A;  5I1U A;  5IK6 A;  3VJD A;  1HXA A;  3OAC A;  3DYH A;  1WY0 A;  4WK5 A;  4LZC A;  3RMG A;  5IL3 A;  1YHL A;  1YJ4 A;  3ACW A;  4OKM A;  4E9Z A;  1YYT A;  3OAB B;  1N20 A;  4JYX A;  2F9K F;  4XQR F;  5B0K A;  3M00 A;  3N1W F;  1V4H A;  3Q30 A;  3VJC A;  3WJN A;  3Q2Z A;  5ILI A;  3LMD A;  4KVI A;  3RYE A;  3ACY A;  2DH4 A;  3PDE A;  4MC8 A;  4NFK F;  2Z4X A;  1N22 A;  3LZ9 A;  3B7L A;  4HD1 A;  2AZK A;  4KFA A;  4E1E A;  3WCJ A;  4LA5 A;  2PS6 A;  3ZL6 A;  3P41 A;  1YV5 A;  4UMJ A;  4LPG F;  3AQB B;  4XQS F;  2PS4 A;  5DIQ F;  2AEK A;  4NUA A;  2F7M F;  4KUX A;  5E8H A;  4RXA A;  1WMW A;  2QIS A;  2E8T A;  2E95 A;  3WCE A;  3RYW A;  4DWG A;  4XQT F;  1ZW5 A;  2F8C F;  2Z4Y A;  4JXY A;  1DGP A;  4NFJ F;  2AZL A;  2ZCR A;  5ERN A;  2E91 A;  1HM7 A;  4L2X F;  2J1O A;  3BNX A;  4KPD A;  4KPJ A;  3KB9 A;  5C05 A;  4F62 A;  4H5D F;  5B0L A;  3WJO A;  3SDT A;  1V4K A;  2E94 A;  4LOB A;  3VJE A;  4LIX A;  4DI5 A;  3LGK A;  5ER8 A;  3OAC B;  5IK0 A;  1RTR A;  3SAE A;  5IKH A;  2ZEV A;  2H8O A;  1VG2 A;  2I19 A;  5IM1 A;  5HNA A;  4LFV F;  2PS5 A;  3QKC A;  1V4I A;  1V4E A;  2Z4W A;  1UBX A;  2E8V A;  3BNY A;  1YQ7 A;  1N1Z A;  2F8Z F;  3AQC B;  3SDR A;  3Q2Q A;  3ICK A;  3KRA A;  3N3D A;  4OGU A;  5ILY A;  1JFA A;  4KQU A;  5DJP F;  3WEJ A;  4RXD A;  3ACX A;  3M0G A;  2ONH A;  4GP2 A;  2E92 A;  5CG5 A;  4KQS A;  1WL3 A;  2F94 F;  3W7F A;  1UBW A;  2VF6 A;  3KBK A;  4KKM A;  5B0M A;  3MAV A;  3NPK A;  4OKZ A;  4PVY F;  5B02 A;  4Q23 A;  5AFX A;  5ERO A;  1VG6 A;  1KIY A;  5AHU B;  3WEF A;  3VJB A;  5JA0 F;  2Z4V A;  4NKE A;  4LTZ A;  3WEK A;  1WKZ A;  2Q58 A;  3M9U A;  5B0J A;  3WEH A;  4DEM F;  5A0I A;  5H9D A;  3G4D A;  3P8R A;  4LA6 A;  3ICM A;  5ILD A;  5DZ2 A;  4P0W A;  3PKO A;  3ID0 A;  3LJI A;  4LLS A;  3N45 F;  3DYG A;  3M01 A;  5KSX F;  3N46 F;  3WSA A;  1RQJ A;  3WCL A;  3AQ0 A;  3IBA A;  3WCC A;  3LOM A;  3WCA A;  3KRA B;  2AEL A;  4LZ3 A;  2Q9Y A;  3NRI A;  2FOR A;  2E8X A;  5CG6 A;  3CP6 A;  4EA2 A;  2F92 F;  4MC3 A;  5EAU A;  3N3L F;  1N23 A;  2FTZ A;  3SDU A;  2E8W A;  4E9U A;  1YHM A;  3ICZ A;  4LTV A;  5E8L A;  4ZQ8 A;  5ILJ A;  5ILK A;  3N49 F;  3ZMB A;  1HXC A;  2ZCS A;  5DGN F;  3TFN A;  2O1O A;  4DHD A;  5IMN A;  5IMI A;  4FJQ A;  4DXJ A;  3CKE A;  5HN9 A;  1YYS A;  5ILZ A;  1VG3 A;  4QPF A;  3TFP A;  3OYR A;  2Z4Z A;  3LEE A;  4LLT A;  4LPH F;  3ASX A;  3ZCD A;  4JVJ F;  2J1P A;  5IMP A;  3KRC B;  1VG7 A;  4EA0 A;  2Z78 A;  3ICN A;  4QXS F;  4RXE A;  5EAS A;  3VJ9 A;  3LVS A;  2RAH A;  4F6V A;  3AE0 A;  2AET A;  3WSB A;  5JV1 F;  1PS1 A;  3LGZ B;  4JZX A;  5EAT A;  1YYU A;  2Z52 A;  2E4O A;  4GA3 A;  4JZB A;  4DZW A;  3WEG A;  4KVW A;  3V1V A;  4F6X A;  4K10 A;  1JFG A;  3QQV A;  3ADZ A;  1WL0 A;  4NKF A;  4P0X A;  5DJV F;  3LDW A;  3PH7 A;  4RYP A;  2E90 A;  1FPS A;  3P8L A;  2OPM A;  3IPI A;  2EWG A;  2PS8 A;  5ERM A;  3EZ3 A;  3S4J A;  5DW7 A;  1DI1 A;  3KRC A;  5IVG A;  3N0G A;  5IKA A;  3PYB A;  3KRF A;  3ZMC A;  1N1B A;  1WL2 A;  5B00 A;  1EZF A;  5B01 A;  3VJ8 A;  1YYQ A;  4LUU A;  4P0V A;  3CC9 A;  3NF2 A;  4KVY A;  3WE9 A;  1WL1 A;  3MZV A;  4LFE A;  3RBM A;  3WCG A;  3Q1O A;  3LSN A;  2Q9Z A;  5A0J A;  5JV2 F;  3N6K F;  5DJR F;  2OPN A;  3N5J F;  4NFI F;  3WCH A;  3EFQ A;  5HN8 A;  3G4F A;  3M02 A;  3KRP A;  3P5R A;  2OA6 A;  4JXN A;  5IN8 A;  3N1V F;  4OMG A;  3SDQ A;  4GP1 A;  3WCB A;  5E8K A;  2ZY1 A;  1HXG A;  3DYF A;  4GAX A;  4LZ0 A;  5B03 A;  2Z7I A;  4LFG A;  5HN7 A;  4NG6 A;  5JV0 F;  3VJA A;  3TC1 A;  3TS7 A;  2PS7 A;  3PYA A;  3APZ A;  3WCM A;  3N5H F;  4N9U A;  5JUZ F;  4OMH A;  3N0F A;  2J5C A;  3V1X A;  2ZCQ A;  3ZOU A;  3KRO B;  2AZJ A;  1YYR A;  3KRF B;  2Z50 A;  4KVD A;  1KIZ A;  3WJK A;  2P1C A;  1VG4 A;  2Z7H A;  3UCA A;  2OGD A;  2F89 F;  1YHK A;  3OAB A;  5DGM F;  5DGS F;  3NPR A;  4FP4 A;  3P5P A;  5DHI A;  5AEL A;  3WCD A;  5IL8 A;  2ONG A;  4N1Z F;  4KK2 A;  1HM4 A;  4KQ5 A;  4LXW A;  5IK9 A;  4RXC A;  3WCI A;  3KRP B;  1V4J A;  1N21 A;  4H5C F;  2ZCO A;  3SDV A;  4DWB A;  3WEI A;  3WCF A;  3TFV A;  3LG5 A;  5A0K A;  2E8U A;  4MC0 A;  3LK5 A;  5ILH A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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