4JZXA

Crystal structure of leshmaniasis major farnesyl diphosphate synthase in complex with 3-butyl-1-(2,2-diphosphonoethyl)pyridinium, ipp and ca2+
Total Genus 156
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
156
sequence length
361
structure length
361
Chain Sequence
AHMERFQKVYEEVQEFLLGDAEKRFEMDVHRKGYLKSMMDTTCLGGKYNRGLCVVDVAEAMAKDTQMDAAAMERVLHDACVCGWMIEMLQAHFLVEDDIMDHSKTRRGKPCWYLHPGVTAQVAINDGLILLAWATQMALHYFADRPFLAEVLRVFHDVDLTTTIGQLYDVTSMVDSAKLDAKVAHANTTDYVEYTPFNHRRIVVYKTAYYTYWLPLVMGLLVSGTLEKVDKKATHKVAMVMGEYFQVQDDVMDCFTPPEKLGKIGTDIEDAKCSWLAVTFLTTAPAEKVAEFKANYGSTDPAAVAVIKQLYTEQNLLARFEEYEKAVVAEVEQLIAALEAQNAAFAASVKVLWSKTYKRQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
molecule keywords Farnesyl pyrophosphate synthase
publication title Structural and thermodynamic basis of the inhibition of Leishmania major farnesyl diphosphate synthase by nitrogen-containing bisphosphonates.
pubmed doi rcsb
source organism Leishmania major
total genus 156
structure length 361
sequence length 361
chains with identical sequence B
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2013-04-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4jzxA00
2F9KF 4MC0A 3SDQA 1YHKA 4RYPA 4HD1A 5IK6A 3KROA 4LLTA 1N20A 4RXCA 2ZEVA 4LOBA 3N3LF 4NG6A 3PYAA 3Q2ZA 3QKCA 2J1PA 2PS7A 3W7FA 4E1EA 2J1OA 3KROB 4NFIF 5C05A 1YYUA 4KQ5A 3LGKA 3PDEA 1N24A 3OACA 3WEKA 5IK9A 2FTZA 1HM7A 1V4IA 5JA0F 3VJBA 5B0MA 1RQIA 5AHUB 5DJRF 4NFJF 3AQCB 2OPNA 4NKEA 2ONGA 5HN8A 3WCAA 3RYEA 3OACB 1YHMA 3M01A 1V4KA 3V1VA 3ZL6A 4Q23A 4GP2A 1WY0A 5IVGA 2J5CA 4KKMA 3DYGA 3P8LA 2Q58A 4DI5A 1ZW5A 2ZCQA 3VJEA 4OGUA 4XQTF 2Z50A 4LXWA 3MAVA 4H5CF 4XQRF 3TC1A 5ILJA 3KB9A 2Z4WA 4NUAA 2OPMA 2PS4A 2ZY1A 4OMGA 1DGPA 3SDTA 5IL8A 3EGTA 3LJIA 4NFKF 3N3DA 1WL1A 2AELA 5DHIA 3ACXA 2E93A 2F8ZF 5B03A 1EZFA 3CP6A 4GA3A 4OKMA 5AELA 1VG3A 3OYRA 1UBWA 3RYWA 3N6KF 2E4OA 4OMHA 5IMNA 3ZOUA 3TFVA 1VG7A 1YYTA 3VJDA 5ER8A 3WE9A 4KVWA 5B0IA 4GP1A 5JV1F 5IN8A 4RXAA 5AYPA 2FORA 3QQVA 1HXGA 2VF6A 1FPSA 4F62A 3N1WF 3WCLA 4N1ZF 1YYQA 5KSXF 3WCEA 3AQBB 4KUXA 1YHLA 4LTVA 4E9UA 2RAHA 4LA6A 1RQJA 4LIXA 3BNYA 2ZEUA 3P5RA 3SDRA 3PH7A 5ILHA 3TFPA 3WC9A 1HX9A 4PVXF 2AZKA 1KIZA 3LMDA 4NKFA 5DJPF 3IPIA 4JXYA 4P0XA 3NPKA 3S4JA 1N1ZA 1VG2A 5DHKA 4H5DF 1RTRA 5DZ2A 3M02A 3VJCA 3N5HF 3DYFA 4ZQ8A 5I1UA 3WEIA 5DGNF 3M00A 1HXAA 4KPDA 3ID0A 4JZXA 4DWBA 3ZMCA 5DW7A 3WJKA 5DGMF 5B00A 4JZBA 1V4JA 3WSAA 5JV0F 1JFAA 2OGDA 2AETA 4RXDA 4LPGF 2ONHA 3LG5A 3WEGA 3G4DA 3N46F 3VJ9A 3MZVA 4KQUA 5E8HA 3Q30A 2Z7HA 3LDWA 2Z4ZA 4XQSF 5HNAA 1WL2A 2F92F 4QXSF 1N21A 5ILZA 2Q9YA 3G4FA 4KVYA 1PS1A 5ERNA 3WCBA 1YJ4A 5E8KA 3LSNA 3V66A 2AZJA 1UBXA 3N0GA 2H8OA 3M9UA 4LFVF 4KFAA 5DGSF 3B7LA 4JXNA 1WL3A 1UBVA 3V1XA 2E92A 4LZCA 5ILIA 3ACWA 5ILYA 3OABA 3RBMA 1HM4A 5JV2F 4KWDA 3ZMBA 5ILDA 3LEEA 3WCCA 3WSBA 4FP4A 3ASXA 3OABB 3WCMA 4DEMF 3N1VF 5B0KA 1JFGA 3LLWA 2OA6A 5CG6A 4RNQA 2EWGA 1VG4A 3KBKA 5B0LA 5H9DA 3SDVA 3WJNA 5IMIA 3NRIA 4DXJA 3VJAA 3P5PA 3N45F 3DYHA 4LZ0A 3KRFA 5ILKA 3ICKA 3WEFA 4P0VA 4LUUA 2Z7IA 3KRPA 2Z4VA 1DI1A 5EAUA 2P1CA 3BNXA 1WL0A 1WKZA 3KRFB 5B01A 3P8RA 1YQ7A 5IM1A 5AFXA 5IK0A 3ADZA 3SAEA 2F7MF 4LFGA 3ICNA 2Z4YA 4EA2A 5IKHA 4KPJA 3KRPB 4LPHF 4KK2A 5IMPA 5CG5A 3RMGA 3KRCA 5HN9A 5A0IA 3N49F 1YYRA 3NPRA 1YYSA 4GAXA 4E9ZA 3KRCB 4DWGA 5IL3A 1HXCA 4EA0A 3VJ8A 5EATA 3N5JF 3ICMA 1N23A 4P0WA 4LFEA 3WJOA 3WCDA 3ACYA 3LZ9A 4KVIA 2E8VA 2E95A 5E8LA 5JUZF 5A0JA 2F94F 2Z4XA 4LA5A 2E90A 1V4EA 3ICZA 2PS5A 2Q80A 3AQ0A 2E8TA 2Z78A 4PVYF 2ZCSA 2AEKA 3LOMA 3PYBA 2E8XA 3TFNA 4DZWA 3TS7A 2E8UA 3AE0A 5B0JA 5B02A 2PS6A 2E91A 3CC9A 4N9UA 2F8CF 4H5EF 2ZCRA 3EFQA 4MC3A 4K10A 4MC8A 2I19A 2ZCOA 5IKAA 1VG6A 3KRAA 3S9VA 2Q9ZA 4FJQA 3WEHA 4DHDA 4QPFA 1YV5A 2E8WA 5DJVF 3IBAA 3PKOA 4KQSA 4KVDA 3KRAB 3WCHA 3NF2A 4F6XA 5EASA 3LGZB 2PS8A 3N0FA 1UBYA 4WK5A 2Z52A 2QISA 4JYXA 4LZ3A 3WCJA 4RXEA 3ZCDA 1KIYA 4F6VA 5HN7A 2AZLA 4UMJA 5A0KA 3APZA 3Q2QA 1N22A 1N1BA 3WEJA 2DH4A 3SDUA 1V4HA 4LTZA 3EZ3A 5ERMA 2O1OA 1WMWA 2E94A 3P41A 4L2XF 3WCIA 2F89F 4JVJF 4OKZA 3M0GA 3LK5A 3Q1OA 5DIQF 3CKEA 3UCAA 3LVSA 4EA1A 3WCGA 5EROA 3WCFA 4LLSA
chains in the Genus database with same CATH superfamily
2F9KF 4MC0A 3SDQA 1YHKA 4RYPA 4HD1A 5IK6A 3KROA 4LLTA 1N20A 4RXCA 2ZEVA 4LOBA 3N3LF 4NG6A 3PYAA 3Q2ZA 3QKCA 2J1PA 2PS7A 3W7FA 4E1EA 2J1OA 3KROB 4NFIF 5C05A 1YYUA 4KQ5A 3LGKA 3PDEA 1N24A 3OACA 3WEKA 5IK9A 2FTZA 1HM7A 1V4IA 5JA0F 3VJBA 5B0MA 1RQIA 5AHUB 5DJRF 4NFJF 3AQCB 2OPNA 4NKEA 2ONGA 5HN8A 3WCAA 3RYEA 3OACB 1YHMA 3M01A 1V4KA 3V1VA 3ZL6A 4Q23A 4GP2A 1WY0A 5IVGA 2J5CA 4KKMA 3DYGA 3P8LA 2Q58A 4DI5A 1ZW5A 2ZCQA 3VJEA 4OGUA 4XQTF 2Z50A 4LXWA 3MAVA 4H5CF 4XQRF 3TC1A 5ILJA 3KB9A 2Z4WA 4NUAA 2OPMA 2PS4A 2ZY1A 4OMGA 1DGPA 3SDTA 5IL8A 3EGTA 3LJIA 4NFKF 3N3DA 1WL1A 2AELA 5DHIA 3ACXA 2E93A 2F8ZF 5B03A 1EZFA 3CP6A 4GA3A 4OKMA 5AELA 1VG3A 3OYRA 1UBWA 3RYWA 3N6KF 2E4OA 4OMHA 5IMNA 3ZOUA 3TFVA 1VG7A 1YYTA 3VJDA 5ER8A 3WE9A 4KVWA 5B0IA 4GP1A 5JV1F 5IN8A 4RXAA 5AYPA 2FORA 3QQVA 1HXGA 2VF6A 1FPSA 4F62A 3N1WF 3WCLA 4N1ZF 1YYQA 5KSXF 3WCEA 3AQBB 4KUXA 1YHLA 4LTVA 4E9UA 2RAHA 4LA6A 1RQJA 4LIXA 3BNYA 2ZEUA 3P5RA 3SDRA 3PH7A 5ILHA 3TFPA 3WC9A 1HX9A 4PVXF 2AZKA 1KIZA 3LMDA 4NKFA 5DJPF 3IPIA 4JXYA 4P0XA 3NPKA 3S4JA 1N1ZA 1VG2A 5DHKA 4H5DF 1RTRA 5DZ2A 3M02A 3VJCA 3N5HF 3DYFA 4ZQ8A 5I1UA 3WEIA 5DGNF 3M00A 1HXAA 4KPDA 3ID0A 4JZXA 4DWBA 3ZMCA 5DW7A 3WJKA 5DGMF 5B00A 4JZBA 1V4JA 3WSAA 5JV0F 1JFAA 2OGDA 2AETA 4RXDA 4LPGF 2ONHA 3LG5A 3WEGA 3G4DA 3N46F 3VJ9A 3MZVA 4KQUA 5E8HA 3Q30A 2Z7HA 3LDWA 2Z4ZA 4XQSF 5HNAA 1WL2A 2F92F 4QXSF 1N21A 5ILZA 2Q9YA 3G4FA 4KVYA 1PS1A 5ERNA 3WCBA 1YJ4A 5E8KA 3LSNA 3V66A 2AZJA 1UBXA 3N0GA 2H8OA 3M9UA 4LFVF 4KFAA 5DGSF 3B7LA 4JXNA 1WL3A 1UBVA 3V1XA 2E92A 4LZCA 5ILIA 3ACWA 5ILYA 3OABA 3RBMA 1HM4A 5JV2F 4KWDA 3ZMBA 5ILDA 3LEEA 3WCCA 3WSBA 4FP4A 3ASXA 3OABB 3WCMA 4DEMF 3N1VF 5B0KA 1JFGA 3LLWA 2OA6A 5CG6A 4RNQA 2EWGA 1VG4A 3KBKA 5B0LA 5H9DA 3SDVA 3WJNA 5IMIA 3NRIA 4DXJA 3VJAA 3P5PA 3N45F 3DYHA 4LZ0A 3KRFA 5ILKA 3ICKA 3WEFA 4P0VA 4LUUA 2Z7IA 3KRPA 2Z4VA 1DI1A 5EAUA 2P1CA 3BNXA 1WL0A 1WKZA 3KRFB 5B01A 3P8RA 1YQ7A 5IM1A 5AFXA 5IK0A 3ADZA 3SAEA 2F7MF 4LFGA 3ICNA 2Z4YA 4EA2A 5IKHA 4KPJA 3KRPB 4LPHF 4KK2A 5IMPA 5CG5A 3RMGA 3KRCA 5HN9A 5A0IA 3N49F 1YYRA 3NPRA 1YYSA 4GAXA 4E9ZA 3KRCB 4DWGA 5IL3A 1HXCA 4EA0A 3VJ8A 5EATA 3N5JF 3ICMA 1N23A 4P0WA 4LFEA 3WJOA 3WCDA 3ACYA 3LZ9A 4KVIA 2E8VA 2E95A 5E8LA 5JUZF 5A0JA 2F94F 2Z4XA 4LA5A 2E90A 1V4EA 3ICZA 2PS5A 2Q80A 3AQ0A 2E8TA 2Z78A 4PVYF 2ZCSA 2AEKA 3LOMA 3PYBA 2E8XA 3TFNA 4DZWA 3TS7A 2E8UA 3AE0A 5B0JA 5B02A 2PS6A 2E91A 3CC9A 4N9UA 2F8CF 4H5EF 2ZCRA 3EFQA 4MC3A 4K10A 4MC8A 2I19A 2ZCOA 5IKAA 1VG6A 3KRAA 3S9VA 2Q9ZA 4FJQA 3WEHA 4DHDA 4QPFA 1YV5A 2E8WA 5DJVF 3IBAA 3PKOA 4KQSA 4KVDA 3KRAB 3WCHA 3NF2A 4F6XA 5EASA 3LGZB 2PS8A 3N0FA 1UBYA 4WK5A 2Z52A 2QISA 4JYXA 4LZ3A 3WCJA 4RXEA 3ZCDA 1KIYA 4F6VA 5HN7A 2AZLA 4UMJA 5A0KA 3APZA 3Q2QA 1N22A 1N1BA 3WEJA 2DH4A 3SDUA 1V4HA 4LTZA 3EZ3A 5ERMA 2O1OA 1WMWA 2E94A 3P41A 4L2XF 3WCIA 2F89F 4JVJF 4OKZA 3M0GA 3LK5A 3Q1OA 5DIQF 3CKEA 3UCAA 3LVSA 4EA1A 3WCGA 5EROA 3WCFA 4LLSA
chains in the Genus database with same CATH topology
2F9KF 4MC0A 3SDQA 1YHKA 4RYPA 4HD1A 5IK6A 3KROA 4LLTA 1N20A 4RXCA 2ZEVA 4LOBA 3N3LF 4NG6A 3PYAA 3Q2ZA 3QKCA 2J1PA 2PS7A 3W7FA 4E1EA 2J1OA 3KROB 4NFIF 5C05A 1YYUA 4KQ5A 3LGKA 3PDEA 1N24A 3OACA 3WEKA 5IK9A 2FTZA 1HM7A 1V4IA 5JA0F 3VJBA 5B0MA 1RQIA 5AHUB 5DJRF 4NFJF 3AQCB 2OPNA 4NKEA 2ONGA 5HN8A 3WCAA 3RYEA 3OACB 1YHMA 3M01A 1V4KA 3V1VA 3ZL6A 4Q23A 4GP2A 1WY0A 5IVGA 2J5CA 4KKMA 3DYGA 3P8LA 2Q58A 4DI5A 1ZW5A 2ZCQA 3VJEA 4OGUA 4XQTF 2Z50A 4LXWA 3MAVA 4H5CF 4XQRF 3TC1A 5ILJA 3KB9A 2Z4WA 4NUAA 2OPMA 2PS4A 2ZY1A 4OMGA 1DGPA 3SDTA 5IL8A 3EGTA 3LJIA 4NFKF 3N3DA 1WL1A 2AELA 5DHIA 3ACXA 2E93A 2F8ZF 5B03A 1EZFA 3CP6A 4GA3A 4OKMA 5AELA 1VG3A 3OYRA 1UBWA 3RYWA 3N6KF 2E4OA 4OMHA 5IMNA 3ZOUA 3TFVA 1VG7A 1YYTA 3VJDA 5ER8A 3WE9A 4KVWA 5B0IA 4GP1A 5JV1F 5IN8A 4RXAA 5AYPA 2FORA 3QQVA 1HXGA 2VF6A 1FPSA 4F62A 3N1WF 3WCLA 4N1ZF 1YYQA 5KSXF 3WCEA 3AQBB 4KUXA 1YHLA 4LTVA 4E9UA 2RAHA 4LA6A 1RQJA 4LIXA 3BNYA 2ZEUA 3P5RA 3SDRA 3PH7A 5ILHA 3TFPA 3WC9A 1HX9A 4PVXF 2AZKA 1KIZA 3LMDA 4NKFA 5DJPF 3IPIA 4JXYA 4P0XA 3NPKA 3S4JA 1N1ZA 1VG2A 5DHKA 4H5DF 1RTRA 5DZ2A 3M02A 3VJCA 3N5HF 3DYFA 4ZQ8A 5I1UA 3WEIA 5DGNF 3M00A 1HXAA 4KPDA 3ID0A 4JZXA 4DWBA 3ZMCA 5DW7A 3WJKA 5DGMF 5B00A 4JZBA 1V4JA 3WSAA 5JV0F 1JFAA 2OGDA 2AETA 4RXDA 4LPGF 2ONHA 3LG5A 3WEGA 3G4DA 3N46F 3VJ9A 3MZVA 4KQUA 5E8HA 3Q30A 2Z7HA 3LDWA 2Z4ZA 4XQSF 5HNAA 1WL2A 2F92F 4QXSF 1N21A 5ILZA 2Q9YA 3G4FA 4KVYA 1PS1A 5ERNA 3WCBA 1YJ4A 5E8KA 3LSNA 3V66A 2AZJA 1UBXA 3N0GA 2H8OA 3M9UA 4LFVF 4KFAA 5DGSF 3B7LA 4JXNA 1WL3A 1UBVA 3V1XA 2E92A 4LZCA 5ILIA 3ACWA 5ILYA 3OABA 3RBMA 1HM4A 5JV2F 4KWDA 3ZMBA 5ILDA 3LEEA 3WCCA 3WSBA 4FP4A 3ASXA 3OABB 3WCMA 4DEMF 3N1VF 5B0KA 1JFGA 3LLWA 2OA6A 5CG6A 4RNQA 2EWGA 1VG4A 3KBKA 5B0LA 5H9DA 3SDVA 3WJNA 5IMIA 3NRIA 4DXJA 3VJAA 3P5PA 3N45F 3DYHA 4LZ0A 3KRFA 5ILKA 3ICKA 3WEFA 4P0VA 4LUUA 2Z7IA 3KRPA 2Z4VA 1DI1A 5EAUA 2P1CA 3BNXA 1WL0A 1WKZA 3KRFB 5B01A 3P8RA 1YQ7A 5IM1A 5AFXA 5IK0A 3ADZA 3SAEA 2F7MF 4LFGA 3ICNA 2Z4YA 4EA2A 5IKHA 4KPJA 3KRPB 4LPHF 4KK2A 5IMPA 5CG5A 3RMGA 3KRCA 5HN9A 5A0IA 3N49F 1YYRA 3NPRA 1YYSA 4GAXA 4E9ZA 3KRCB 4DWGA 5IL3A 1HXCA 4EA0A 3VJ8A 5EATA 3N5JF 3ICMA 1N23A 4P0WA 4LFEA 3WJOA 3WCDA 3ACYA 3LZ9A 4KVIA 2E8VA 2E95A 5E8LA 5JUZF 5A0JA 2F94F 2Z4XA 4LA5A 2E90A 1V4EA 3ICZA 2PS5A 2Q80A 3AQ0A 2E8TA 2Z78A 4PVYF 2ZCSA 2AEKA 3LOMA 3PYBA 2E8XA 3TFNA 4DZWA 3TS7A 2E8UA 3AE0A 5B0JA 5B02A 2PS6A 2E91A 3CC9A 4N9UA 2F8CF 4H5EF 2ZCRA 3EFQA 4MC3A 4K10A 4MC8A 2I19A 2ZCOA 5IKAA 1VG6A 3KRAA 3S9VA 2Q9ZA 4FJQA 3WEHA 4DHDA 4QPFA 1YV5A 2E8WA 5DJVF 3IBAA 3PKOA 4KQSA 4KVDA 3KRAB 3WCHA 3NF2A 4F6XA 5EASA 3LGZB 2PS8A 3N0FA 1UBYA 4WK5A 2Z52A 2QISA 4JYXA 4LZ3A 3WCJA 4RXEA 3ZCDA 1KIYA 4F6VA 5HN7A 2AZLA 4UMJA 5A0KA 3APZA 3Q2QA 1N22A 1N1BA 3WEJA 2DH4A 3SDUA 1V4HA 4LTZA 3EZ3A 5ERMA 2O1OA 1WMWA 2E94A 3P41A 4L2XF 3WCIA 2F89F 4JVJF 4OKZA 3M0GA 3LK5A 3Q1OA 5DIQF 3CKEA 3UCAA 3LVSA 4EA1A 3WCGA 5EROA 3WCFA 4LLSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2F9K F;  4MC0 A;  3SDQ A;  1YHK A;  4RYP A;  4HD1 A;  5IK6 A;  3KRO A;  4LLT A;  1N20 A;  4RXC A;  2ZEV A;  4LOB A;  3N3L F;  4NG6 A;  3PYA A;  3Q2Z A;  3QKC A;  2J1P A;  2PS7 A;  3W7F A;  4E1E A;  2J1O A;  3KRO B;  4NFI F;  5C05 A;  1YYU A;  4KQ5 A;  3LGK A;  3PDE A;  1N24 A;  3OAC A;  3WEK A;  5IK9 A;  2FTZ A;  1HM7 A;  1V4I A;  5JA0 F;  3VJB A;  5B0M A;  1RQI A;  5AHU B;  5DJR F;  4NFJ F;  3AQC B;  2OPN A;  4NKE A;  2ONG A;  5HN8 A;  3WCA A;  3RYE A;  3OAC B;  1YHM A;  3M01 A;  1V4K A;  3V1V A;  3ZL6 A;  4Q23 A;  4GP2 A;  1WY0 A;  5IVG A;  2J5C A;  4KKM A;  3DYG A;  3P8L A;  2Q58 A;  4DI5 A;  1ZW5 A;  2ZCQ A;  3VJE A;  4OGU A;  4XQT F;  2Z50 A;  4LXW A;  3MAV A;  4H5C F;  4XQR F;  3TC1 A;  5ILJ A;  3KB9 A;  2Z4W A;  4NUA A;  2OPM A;  2PS4 A;  2ZY1 A;  4OMG A;  1DGP A;  3SDT A;  5IL8 A;  3EGT A;  3LJI A;  4NFK F;  3N3D A;  1WL1 A;  2AEL A;  5DHI A;  3ACX A;  2E93 A;  2F8Z F;  5B03 A;  1EZF A;  3CP6 A;  4GA3 A;  4OKM A;  5AEL A;  1VG3 A;  3OYR A;  1UBW A;  3RYW A;  3N6K F;  2E4O A;  4OMH A;  5IMN A;  3ZOU A;  3TFV A;  1VG7 A;  1YYT A;  3VJD A;  5ER8 A;  3WE9 A;  4KVW A;  5B0I A;  4GP1 A;  5JV1 F;  5IN8 A;  4RXA A;  5AYP A;  2FOR A;  3QQV A;  1HXG A;  2VF6 A;  1FPS A;  4F62 A;  3N1W F;  3WCL A;  4N1Z F;  1YYQ A;  5KSX F;  3WCE A;  3AQB B;  4KUX A;  1YHL A;  4LTV A;  4E9U A;  2RAH A;  4LA6 A;  1RQJ A;  4LIX A;  3BNY A;  2ZEU A;  3P5R A;  3SDR A;  3PH7 A;  5ILH A;  3TFP A;  3WC9 A;  1HX9 A;  4PVX F;  2AZK A;  1KIZ A;  3LMD A;  4NKF A;  5DJP F;  3IPI A;  4JXY A;  4P0X A;  3NPK A;  3S4J A;  1N1Z A;  1VG2 A;  5DHK A;  4H5D F;  1RTR A;  5DZ2 A;  3M02 A;  3VJC A;  3N5H F;  3DYF A;  4ZQ8 A;  5I1U A;  3WEI A;  5DGN F;  3M00 A;  1HXA A;  4KPD A;  3ID0 A;  4JZX A;  4DWB A;  3ZMC A;  5DW7 A;  3WJK A;  5DGM F;  5B00 A;  4JZB A;  1V4J A;  3WSA A;  5JV0 F;  1JFA A;  2OGD A;  2AET A;  4RXD A;  4LPG F;  2ONH A;  3LG5 A;  3WEG A;  3G4D A;  3N46 F;  3VJ9 A;  3MZV A;  4KQU A;  5E8H A;  3Q30 A;  2Z7H A;  3LDW A;  2Z4Z A;  4XQS F;  5HNA A;  1WL2 A;  2F92 F;  4QXS F;  1N21 A;  5ILZ A;  2Q9Y A;  3G4F A;  4KVY A;  1PS1 A;  5ERN A;  3WCB A;  1YJ4 A;  5E8K A;  3LSN A;  3V66 A;  2AZJ A;  1UBX A;  3N0G A;  2H8O A;  3M9U A;  4LFV F;  4KFA A;  5DGS F;  3B7L A;  4JXN A;  1WL3 A;  1UBV A;  3V1X A;  2E92 A;  4LZC A;  5ILI A;  3ACW A;  5ILY A;  3OAB A;  3RBM A;  1HM4 A;  5JV2 F;  4KWD A;  3ZMB A;  5ILD A;  3LEE A;  3WCC A;  3WSB A;  4FP4 A;  3ASX A;  3OAB B;  3WCM A;  4DEM F;  3N1V F;  5B0K A;  1JFG A;  3LLW A;  2OA6 A;  5CG6 A;  4RNQ A;  2EWG A;  1VG4 A;  3KBK A;  5B0L A;  5H9D A;  3SDV A;  3WJN A;  5IMI A;  3NRI A;  4DXJ A;  3VJA A;  3P5P A;  3N45 F;  3DYH A;  4LZ0 A;  3KRF A;  5ILK A;  3ICK A;  3WEF A;  4P0V A;  4LUU A;  2Z7I A;  3KRP A;  2Z4V A;  1DI1 A;  5EAU A;  2P1C A;  3BNX A;  1WL0 A;  1WKZ A;  3KRF B;  5B01 A;  3P8R A;  1YQ7 A;  5IM1 A;  5AFX A;  5IK0 A;  3ADZ A;  3SAE A;  2F7M F;  4LFG A;  3ICN A;  2Z4Y A;  4EA2 A;  5IKH A;  4KPJ A;  3KRP B;  4LPH F;  4KK2 A;  5IMP A;  5CG5 A;  3RMG A;  3KRC A;  5HN9 A;  5A0I A;  3N49 F;  1YYR A;  3NPR A;  1YYS A;  4GAX A;  4E9Z A;  3KRC B;  4DWG A;  5IL3 A;  1HXC A;  4EA0 A;  3VJ8 A;  5EAT A;  3N5J F;  3ICM A;  1N23 A;  4P0W A;  4LFE A;  3WJO A;  3WCD A;  3ACY A;  3LZ9 A;  4KVI A;  2E8V A;  2E95 A;  5E8L A;  5JUZ F;  5A0J A;  2F94 F;  2Z4X A;  4LA5 A;  2E90 A;  1V4E A;  3ICZ A;  2PS5 A;  2Q80 A;  3AQ0 A;  2E8T A;  2Z78 A;  4PVY F;  2ZCS A;  2AEK A;  3LOM A;  3PYB A;  2E8X A;  3TFN A;  4DZW A;  3TS7 A;  2E8U A;  3AE0 A;  5B0J A;  5B02 A;  2PS6 A;  2E91 A;  3CC9 A;  4N9U A;  2F8C F;  4H5E F;  2ZCR A;  3EFQ A;  4MC3 A;  4K10 A;  4MC8 A;  2I19 A;  2ZCO A;  5IKA A;  1VG6 A;  3KRA A;  3S9V A;  2Q9Z A;  4FJQ A;  3WEH A;  4DHD A;  4QPF A;  1YV5 A;  2E8W A;  5DJV F;  3IBA A;  3PKO A;  4KQS A;  4KVD A;  3KRA B;  3WCH A;  3NF2 A;  4F6X A;  5EAS A;  3LGZ B;  2PS8 A;  3N0F A;  1UBY A;  4WK5 A;  2Z52 A;  2QIS A;  4JYX A;  4LZ3 A;  3WCJ A;  4RXE A;  3ZCD A;  1KIY A;  4F6V A;  5HN7 A;  2AZL A;  4UMJ A;  5A0K A;  3APZ A;  3Q2Q A;  1N22 A;  1N1B A;  3WEJ A;  2DH4 A;  3SDU A;  1V4H A;  4LTZ A;  3EZ3 A;  5ERM A;  2O1O A;  1WMW A;  2E94 A;  3P41 A;  4L2X F;  3WCI A;  2F89 F;  4JVJ F;  4OKZ A;  3M0G A;  3LK5 A;  3Q1O A;  5DIQ F;  3CKE A;  3UCA A;  3LVS A;  4EA1 A;  3WCG A;  5ERO A;  3WCF A;  4LLS A; 
#chains in the Genus database with same CATH topology
 2F9K F;  4MC0 A;  3SDQ A;  1YHK A;  4RYP A;  4HD1 A;  5IK6 A;  3KRO A;  4LLT A;  1N20 A;  4RXC A;  2ZEV A;  4LOB A;  3N3L F;  4NG6 A;  3PYA A;  3Q2Z A;  3QKC A;  2J1P A;  2PS7 A;  3W7F A;  4E1E A;  2J1O A;  3KRO B;  4NFI F;  5C05 A;  1YYU A;  4KQ5 A;  3LGK A;  3PDE A;  1N24 A;  3OAC A;  3WEK A;  5IK9 A;  2FTZ A;  1HM7 A;  1V4I A;  5JA0 F;  3VJB A;  5B0M A;  1RQI A;  5AHU B;  5DJR F;  4NFJ F;  3AQC B;  2OPN A;  4NKE A;  2ONG A;  5HN8 A;  3WCA A;  3RYE A;  3OAC B;  1YHM A;  3M01 A;  1V4K A;  3V1V A;  3ZL6 A;  4Q23 A;  4GP2 A;  1WY0 A;  5IVG A;  2J5C A;  4KKM A;  3DYG A;  3P8L A;  2Q58 A;  4DI5 A;  1ZW5 A;  2ZCQ A;  3VJE A;  4OGU A;  4XQT F;  2Z50 A;  4LXW A;  3MAV A;  4H5C F;  4XQR F;  3TC1 A;  5ILJ A;  3KB9 A;  2Z4W A;  4NUA A;  2OPM A;  2PS4 A;  2ZY1 A;  4OMG A;  1DGP A;  3SDT A;  5IL8 A;  3EGT A;  3LJI A;  4NFK F;  3N3D A;  1WL1 A;  2AEL A;  5DHI A;  3ACX A;  2E93 A;  2F8Z F;  5B03 A;  1EZF A;  3CP6 A;  4GA3 A;  4OKM A;  5AEL A;  1VG3 A;  3OYR A;  1UBW A;  3RYW A;  3N6K F;  2E4O A;  4OMH A;  5IMN A;  3ZOU A;  3TFV A;  1VG7 A;  1YYT A;  3VJD A;  5ER8 A;  3WE9 A;  4KVW A;  5B0I A;  4GP1 A;  5JV1 F;  5IN8 A;  4RXA A;  5AYP A;  2FOR A;  3QQV A;  1HXG A;  2VF6 A;  1FPS A;  4F62 A;  3N1W F;  3WCL A;  4N1Z F;  1YYQ A;  5KSX F;  3WCE A;  3AQB B;  4KUX A;  1YHL A;  4LTV A;  4E9U A;  2RAH A;  4LA6 A;  1RQJ A;  4LIX A;  3BNY A;  2ZEU A;  3P5R A;  3SDR A;  3PH7 A;  5ILH A;  3TFP A;  3WC9 A;  1HX9 A;  4PVX F;  2AZK A;  1KIZ A;  3LMD A;  4NKF A;  5DJP F;  3IPI A;  4JXY A;  4P0X A;  3NPK A;  3S4J A;  1N1Z A;  1VG2 A;  5DHK A;  4H5D F;  1RTR A;  5DZ2 A;  3M02 A;  3VJC A;  3N5H F;  3DYF A;  4ZQ8 A;  5I1U A;  3WEI A;  5DGN F;  3M00 A;  1HXA A;  4KPD A;  3ID0 A;  4JZX A;  4DWB A;  3ZMC A;  5DW7 A;  3WJK A;  5DGM F;  5B00 A;  4JZB A;  1V4J A;  3WSA A;  5JV0 F;  1JFA A;  2OGD A;  2AET A;  4RXD A;  4LPG F;  2ONH A;  3LG5 A;  3WEG A;  3G4D A;  3N46 F;  3VJ9 A;  3MZV A;  4KQU A;  5E8H A;  3Q30 A;  2Z7H A;  3LDW A;  2Z4Z A;  4XQS F;  5HNA A;  1WL2 A;  2F92 F;  4QXS F;  1N21 A;  5ILZ A;  2Q9Y A;  3G4F A;  4KVY A;  1PS1 A;  5ERN A;  3WCB A;  1YJ4 A;  5E8K A;  3LSN A;  3V66 A;  2AZJ A;  1UBX A;  3N0G A;  2H8O A;  3M9U A;  4LFV F;  4KFA A;  5DGS F;  3B7L A;  4JXN A;  1WL3 A;  1UBV A;  3V1X A;  2E92 A;  4LZC A;  5ILI A;  3ACW A;  5ILY A;  3OAB A;  3RBM A;  1HM4 A;  5JV2 F;  4KWD A;  3ZMB A;  5ILD A;  3LEE A;  3WCC A;  3WSB A;  4FP4 A;  3ASX A;  3OAB B;  3WCM A;  4DEM F;  3N1V F;  5B0K A;  1JFG A;  3LLW A;  2OA6 A;  5CG6 A;  4RNQ A;  2EWG A;  1VG4 A;  3KBK A;  5B0L A;  5H9D A;  3SDV A;  3WJN A;  5IMI A;  3NRI A;  4DXJ A;  3VJA A;  3P5P A;  3N45 F;  3DYH A;  4LZ0 A;  3KRF A;  5ILK A;  3ICK A;  3WEF A;  4P0V A;  4LUU A;  2Z7I A;  3KRP A;  2Z4V A;  1DI1 A;  5EAU A;  2P1C A;  3BNX A;  1WL0 A;  1WKZ A;  3KRF B;  5B01 A;  3P8R A;  1YQ7 A;  5IM1 A;  5AFX A;  5IK0 A;  3ADZ A;  3SAE A;  2F7M F;  4LFG A;  3ICN A;  2Z4Y A;  4EA2 A;  5IKH A;  4KPJ A;  3KRP B;  4LPH F;  4KK2 A;  5IMP A;  5CG5 A;  3RMG A;  3KRC A;  5HN9 A;  5A0I A;  3N49 F;  1YYR A;  3NPR A;  1YYS A;  4GAX A;  4E9Z A;  3KRC B;  4DWG A;  5IL3 A;  1HXC A;  4EA0 A;  3VJ8 A;  5EAT A;  3N5J F;  3ICM A;  1N23 A;  4P0W A;  4LFE A;  3WJO A;  3WCD A;  3ACY A;  3LZ9 A;  4KVI A;  2E8V A;  2E95 A;  5E8L A;  5JUZ F;  5A0J A;  2F94 F;  2Z4X A;  4LA5 A;  2E90 A;  1V4E A;  3ICZ A;  2PS5 A;  2Q80 A;  3AQ0 A;  2E8T A;  2Z78 A;  4PVY F;  2ZCS A;  2AEK A;  3LOM A;  3PYB A;  2E8X A;  3TFN A;  4DZW A;  3TS7 A;  2E8U A;  3AE0 A;  5B0J A;  5B02 A;  2PS6 A;  2E91 A;  3CC9 A;  4N9U A;  2F8C F;  4H5E F;  2ZCR A;  3EFQ A;  4MC3 A;  4K10 A;  4MC8 A;  2I19 A;  2ZCO A;  5IKA A;  1VG6 A;  3KRA A;  3S9V A;  2Q9Z A;  4FJQ A;  3WEH A;  4DHD A;  4QPF A;  1YV5 A;  2E8W A;  5DJV F;  3IBA A;  3PKO A;  4KQS A;  4KVD A;  3KRA B;  3WCH A;  3NF2 A;  4F6X A;  5EAS A;  3LGZ B;  2PS8 A;  3N0F A;  1UBY A;  4WK5 A;  2Z52 A;  2QIS A;  4JYX A;  4LZ3 A;  3WCJ A;  4RXE A;  3ZCD A;  1KIY A;  4F6V A;  5HN7 A;  2AZL A;  4UMJ A;  5A0K A;  3APZ A;  3Q2Q A;  1N22 A;  1N1B A;  3WEJ A;  2DH4 A;  3SDU A;  1V4H A;  4LTZ A;  3EZ3 A;  5ERM A;  2O1O A;  1WMW A;  2E94 A;  3P41 A;  4L2X F;  3WCI A;  2F89 F;  4JVJ F;  4OKZ A;  3M0G A;  3LK5 A;  3Q1O A;  5DIQ F;  3CKE A;  3UCA A;  3LVS A;  4EA1 A;  3WCG A;  5ERO A;  3WCF A;  4LLS A; 
#chains in the Genus database with same CATH homology
 2F9K F;  4MC0 A;  3SDQ A;  1YHK A;  4RYP A;  4HD1 A;  5IK6 A;  3KRO A;  4LLT A;  1N20 A;  4RXC A;  2ZEV A;  4LOB A;  3N3L F;  4NG6 A;  3PYA A;  3Q2Z A;  3QKC A;  2J1P A;  2PS7 A;  3W7F A;  4E1E A;  2J1O A;  3KRO B;  4NFI F;  5C05 A;  1YYU A;  4KQ5 A;  3LGK A;  3PDE A;  1N24 A;  3OAC A;  3WEK A;  5IK9 A;  2FTZ A;  1HM7 A;  1V4I A;  5JA0 F;  3VJB A;  5B0M A;  1RQI A;  5AHU B;  5DJR F;  4NFJ F;  3AQC B;  2OPN A;  4NKE A;  2ONG A;  5HN8 A;  3WCA A;  3RYE A;  3OAC B;  1YHM A;  3M01 A;  1V4K A;  3V1V A;  3ZL6 A;  4Q23 A;  4GP2 A;  1WY0 A;  5IVG A;  2J5C A;  4KKM A;  3DYG A;  3P8L A;  2Q58 A;  4DI5 A;  1ZW5 A;  2ZCQ A;  3VJE A;  4OGU A;  4XQT F;  2Z50 A;  4LXW A;  3MAV A;  4H5C F;  4XQR F;  3TC1 A;  5ILJ A;  3KB9 A;  2Z4W A;  4NUA A;  2OPM A;  2PS4 A;  2ZY1 A;  4OMG A;  1DGP A;  3SDT A;  5IL8 A;  3EGT A;  3LJI A;  4NFK F;  3N3D A;  1WL1 A;  2AEL A;  5DHI A;  3ACX A;  2E93 A;  2F8Z F;  5B03 A;  1EZF A;  3CP6 A;  4GA3 A;  4OKM A;  5AEL A;  1VG3 A;  3OYR A;  1UBW A;  3RYW A;  3N6K F;  2E4O A;  4OMH A;  5IMN A;  3ZOU A;  3TFV A;  1VG7 A;  1YYT A;  3VJD A;  5ER8 A;  3WE9 A;  4KVW A;  5B0I A;  4GP1 A;  5JV1 F;  5IN8 A;  4RXA A;  5AYP A;  2FOR A;  3QQV A;  1HXG A;  2VF6 A;  1FPS A;  4F62 A;  3N1W F;  3WCL A;  4N1Z F;  1YYQ A;  5KSX F;  3WCE A;  3AQB B;  4KUX A;  1YHL A;  4LTV A;  4E9U A;  2RAH A;  4LA6 A;  1RQJ A;  4LIX A;  3BNY A;  2ZEU A;  3P5R A;  3SDR A;  3PH7 A;  5ILH A;  3TFP A;  3WC9 A;  1HX9 A;  4PVX F;  2AZK A;  1KIZ A;  3LMD A;  4NKF A;  5DJP F;  3IPI A;  4JXY A;  4P0X A;  3NPK A;  3S4J A;  1N1Z A;  1VG2 A;  5DHK A;  4H5D F;  1RTR A;  5DZ2 A;  3M02 A;  3VJC A;  3N5H F;  3DYF A;  4ZQ8 A;  5I1U A;  3WEI A;  5DGN F;  3M00 A;  1HXA A;  4KPD A;  3ID0 A;  4JZX A;  4DWB A;  3ZMC A;  5DW7 A;  3WJK A;  5DGM F;  5B00 A;  4JZB A;  1V4J A;  3WSA A;  5JV0 F;  1JFA A;  2OGD A;  2AET A;  4RXD A;  4LPG F;  2ONH A;  3LG5 A;  3WEG A;  3G4D A;  3N46 F;  3VJ9 A;  3MZV A;  4KQU A;  5E8H A;  3Q30 A;  2Z7H A;  3LDW A;  2Z4Z A;  4XQS F;  5HNA A;  1WL2 A;  2F92 F;  4QXS F;  1N21 A;  5ILZ A;  2Q9Y A;  3G4F A;  4KVY A;  1PS1 A;  5ERN A;  3WCB A;  1YJ4 A;  5E8K A;  3LSN A;  3V66 A;  2AZJ A;  1UBX A;  3N0G A;  2H8O A;  3M9U A;  4LFV F;  4KFA A;  5DGS F;  3B7L A;  4JXN A;  1WL3 A;  1UBV A;  3V1X A;  2E92 A;  4LZC A;  5ILI A;  3ACW A;  5ILY A;  3OAB A;  3RBM A;  1HM4 A;  5JV2 F;  4KWD A;  3ZMB A;  5ILD A;  3LEE A;  3WCC A;  3WSB A;  4FP4 A;  3ASX A;  3OAB B;  3WCM A;  4DEM F;  3N1V F;  5B0K A;  1JFG A;  3LLW A;  2OA6 A;  5CG6 A;  4RNQ A;  2EWG A;  1VG4 A;  3KBK A;  5B0L A;  5H9D A;  3SDV A;  3WJN A;  5IMI A;  3NRI A;  4DXJ A;  3VJA A;  3P5P A;  3N45 F;  3DYH A;  4LZ0 A;  3KRF A;  5ILK A;  3ICK A;  3WEF A;  4P0V A;  4LUU A;  2Z7I A;  3KRP A;  2Z4V A;  1DI1 A;  5EAU A;  2P1C A;  3BNX A;  1WL0 A;  1WKZ A;  3KRF B;  5B01 A;  3P8R A;  1YQ7 A;  5IM1 A;  5AFX A;  5IK0 A;  3ADZ A;  3SAE A;  2F7M F;  4LFG A;  3ICN A;  2Z4Y A;  4EA2 A;  5IKH A;  4KPJ A;  3KRP B;  4LPH F;  4KK2 A;  5IMP A;  5CG5 A;  3RMG A;  3KRC A;  5HN9 A;  5A0I A;  3N49 F;  1YYR A;  3NPR A;  1YYS A;  4GAX A;  4E9Z A;  3KRC B;  4DWG A;  5IL3 A;  1HXC A;  4EA0 A;  3VJ8 A;  5EAT A;  3N5J F;  3ICM A;  1N23 A;  4P0W A;  4LFE A;  3WJO A;  3WCD A;  3ACY A;  3LZ9 A;  4KVI A;  2E8V A;  2E95 A;  5E8L A;  5JUZ F;  5A0J A;  2F94 F;  2Z4X A;  4LA5 A;  2E90 A;  1V4E A;  3ICZ A;  2PS5 A;  2Q80 A;  3AQ0 A;  2E8T A;  2Z78 A;  4PVY F;  2ZCS A;  2AEK A;  3LOM A;  3PYB A;  2E8X A;  3TFN A;  4DZW A;  3TS7 A;  2E8U A;  3AE0 A;  5B0J A;  5B02 A;  2PS6 A;  2E91 A;  3CC9 A;  4N9U A;  2F8C F;  4H5E F;  2ZCR A;  3EFQ A;  4MC3 A;  4K10 A;  4MC8 A;  2I19 A;  2ZCO A;  5IKA A;  1VG6 A;  3KRA A;  3S9V A;  2Q9Z A;  4FJQ A;  3WEH A;  4DHD A;  4QPF A;  1YV5 A;  2E8W A;  5DJV F;  3IBA A;  3PKO A;  4KQS A;  4KVD A;  3KRA B;  3WCH A;  3NF2 A;  4F6X A;  5EAS A;  3LGZ B;  2PS8 A;  3N0F A;  1UBY A;  4WK5 A;  2Z52 A;  2QIS A;  4JYX A;  4LZ3 A;  3WCJ A;  4RXE A;  3ZCD A;  1KIY A;  4F6V A;  5HN7 A;  2AZL A;  4UMJ A;  5A0K A;  3APZ A;  3Q2Q A;  1N22 A;  1N1B A;  3WEJ A;  2DH4 A;  3SDU A;  1V4H A;  4LTZ A;  3EZ3 A;  5ERM A;  2O1O A;  1WMW A;  2E94 A;  3P41 A;  4L2X F;  3WCI A;  2F89 F;  4JVJ F;  4OKZ A;  3M0G A;  3LK5 A;  3Q1O A;  5DIQ F;  3CKE A;  3UCA A;  3LVS A;  4EA1 A;  3WCG A;  5ERO A;  3WCF A;  4LLS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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