4QPFA

New lower bone affinity bisphosphonate drug design for effective use in diseases characterized by abnormal bone resorption
Total Genus 133
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
133
sequence length
342
structure length
337
Chain Sequence
VYAQEKQDFVQHFSQIVRVLTEPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords Farnesyl pyrophosphate synthase
publication title New lower bone affinity bisphosphonate drug design for effective use in diseases characterized by abnormal bone resorption
rcsb
source organism Homo sapiens
total genus 133
structure length 337
sequence length 342
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2014-06-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4qpfA00
1ZW5A 2OPMA 2Q80A 3DYHA 1YYSA 3VJ8A 4RXDA 4H5DF 4XQSF 3WC9A 3WJOA 3WJKA 3W7FA 3LGKA 2PS7A 2E95A 4F6XA 3ACXA 2EWGA 3N1WF 2F8ZF 3KB9A 2E93A 3ICNA 1WL2A 2FORA 1YQ7A 3MZVA 4KVWA 4DEMF 4XQTF 1HM7A 4KQSA 5IMPA 5HN8A 1YHLA 3BNXA 3PH7A 4WK5A 1DGPA 3N6KF 5A0IA 1WL3A 2J1OA 2ZCOA 3PYBA 4P0WA 5H9DA 5E8LA 4NKEA 3LVSA 4LFVF 2E8TA 3N3LF 3VJAA 3N0GA 3OABB 2AZKA 5I1UA 1WMWA 3VJBA 5CG6A 2Z7IA 3B7LA 4F6VA 5IKHA 5ERNA 3WCEA 3TFVA 3WCCA 3CKEA 1VG4A 2H8OA 3LG5A 4RXAA 3TS7A 4RYPA 3IPIA 5IVGA 4UMJA 1EZFA 3BNYA 5IMNA 3S9VA 3LK5A 4RXEA 5ERMA 5AYPA 5IK6A 4OMGA 2ONHA 4KQ5A 4JVJF 3N5HF 3WCBA 3OABA 1HXCA 2Z4WA 3UCAA 3KROA 4N9UA 5B02A 4KVDA 3WCGA 3WCLA 4F62A 4GP2A 4GP1A 2E94A 3P8LA 3G4DA 5B0MA 5IL8A 3TFPA 1VG6A 2E8XA 4LTVA 4LLTA 2Z50A 2AELA 5HN9A 4LXWA 1N24A 2VF6A 3NRIA 3LEEA 5IK0A 1N20A 3WCDA 4MC0A 3SDVA 5DJVF 4K10A 1HM4A 3ZOUA 2Z4ZA 3OACA 3Q30A 3CC9A 1UBWA 1VG7A 5C05A 3N46F 4FP4A 3M0GA 3SDQA 3M02A 4LLSA 3ICMA 5HNAA 3IBAA 3DYGA 1RQJA 4LA5A 3WJNA 1V4EA 4OKZA 4JZBA 3N0FA 4LPHF 3P41A 5CG5A 2AEKA 3VJ9A 4MC3A 2E92A 4RXCA 5JV2F 3ZL6A 3ZMCA 1UBVA 1YV5A 5IK9A 2Z7HA 3APZA 3Q1OA 3CP6A 1KIYA 3P8RA 1FPSA 4EA2A 2ZCRA 4OGUA 3EFQA 5DGSF 2I19A 5DJPF 5AFXA 5JA0F 3ZMBA 4H5CF 1RTRA 2E91A 5DZ2A 3WEHA 1HXGA 4KKMA 5A0KA 4OMHA 4LTZA 5JUZF 2Q9ZA 3KRFB 2F92F 5B0LA 2F9KF 3LOMA 3LSNA 4QXSF 3EGTA 3V66A 5DHKA 3VJDA 1VG3A 3RYEA 3SDUA 3P5RA 3LLWA 4P0VA 4RNQA 2Q9YA 2Z4VA 4LOBA 2Z4YA 3WEFA 5E8KA 3AE0A 3RMGA 4DHDA 3TFNA 5DJRF 2ZY1A 1WKZA 2ZCQA 1RQIA 4GAXA 3WSAA 3LGZB 3WEGA 2AZLA 2ZCSA 3N49F 5EASA 4KWDA 2ZEUA 3V1VA 2F94F 3ACWA 1HXAA 4E9UA 5EAUA 2DH4A 1YYUA 3AQ0A 3S4JA 3ZCDA 1JFGA 3AQCB 4E1EA 5IM1A 2OPNA 1YYRA 1N22A 3N5JF 1V4KA 2J1PA 3WEKA 3ID0A 5ILIA 4OKMA 5JV0F 3KRCB 1KIZA 3ADZA 4EA1A 4N1ZF 3N1VF 5ILYA 2Z4XA 3QKCA 1YHMA 4DZWA 5DHIA 4LUUA 2Z52A 1V4HA 3KRAB 4E9ZA 3QQVA 3P5PA 4PVYF 4NFJF 2AETA 3SDTA 5B00A 2QISA 3PDEA 4NFIF 5E8HA 4L2XF 3Q2QA 4MC8A 4ZQ8A 2ZEVA 3AQBB 2OA6A 5DGNF 4LFEA 2F7MF 1HX9A 5B0IA 4DWBA 2E8VA 4H5EF 4NUAA 4HD1A 4NG6A 4XQRF 5IL3A 3KBKA 1DI1A 4QPFA 2E90A 3NPRA 5EATA 3ICZA 4JYXA 4DXJA 3EZ3A 4KPDA 3KRAA 4P0XA 1V4JA 3RYWA 5JV1F 1N1BA 5KSXF 5B01A 3NF2A 3VJEA 3WCIA 3LJIA 4LZCA 1PS1A 5AELA 4KK2A 3LZ9A 3WE9A 1WL1A 2E8WA 3RBMA 5ILDA 5A0JA 5IN8A 5ILZA 4KPJA 5DGMF 4DWGA 3ACYA 4LZ3A 4KFAA 3WEIA 3V1XA 4NKFA 5B0KA 3N3DA 2P1CA 3TC1A 2PS5A 3LDWA 5ILHA 5B03A 2PS6A 2O1OA 3KROB 3N45F 1N21A 2RAHA 1WY0A 5IKAA 1UBXA 3G4FA 2OGDA 4KVYA 3PYAA 3KRPB 2PS4A 3KRFA 1N23A 3SDRA 3ICKA 3WCFA 4JXYA 1YYQA 3WCJA 5DIQF 3WEJA 4FJQA 4LPGF 4EA0A 1YJ4A 2E4OA 3OACB 3MAVA 4JZXA 3WCAA 3NPKA 3WSBA 3M01A 2Z78A 4KUXA 1WL0A 4LIXA 5EROA 3DYFA 2F89F 3WCMA 3WCHA 2E8UA 3SAEA 3Q2ZA 4KVIA 4Q23A 3PKOA 5ER8A 2FTZA 1VG2A 1N1ZA 1JFAA 3KRPA 3OYRA 1YHKA 2PS8A 4DI5A 5ILJA 4LZ0A 3M9UA 4NFKF 4PVXF 4KQUA 2J5CA 5IMIA 5HN7A 5ILKA 3ASXA 5AHUB 4GA3A 5B0JA 3LMDA 2F8CF 1YYTA 2AZJA 3VJCA 1UBYA 4LA6A 2Q58A 2ONGA 1V4IA 3KRCA 5DW7A 4LFGA 4JXNA 3M00A
chains in the Genus database with same CATH superfamily
1ZW5A 2OPMA 2Q80A 3DYHA 1YYSA 3VJ8A 4RXDA 4H5DF 4XQSF 3WC9A 3WJOA 3WJKA 3W7FA 3LGKA 2PS7A 2E95A 4F6XA 3ACXA 2EWGA 3N1WF 2F8ZF 3KB9A 2E93A 3ICNA 1WL2A 2FORA 1YQ7A 3MZVA 4KVWA 4DEMF 4XQTF 1HM7A 4KQSA 5IMPA 5HN8A 1YHLA 3BNXA 3PH7A 4WK5A 1DGPA 3N6KF 5A0IA 1WL3A 2J1OA 2ZCOA 3PYBA 4P0WA 5H9DA 5E8LA 4NKEA 3LVSA 4LFVF 2E8TA 3N3LF 3VJAA 3N0GA 3OABB 2AZKA 5I1UA 1WMWA 3VJBA 5CG6A 2Z7IA 3B7LA 4F6VA 5IKHA 5ERNA 3WCEA 3TFVA 3WCCA 3CKEA 1VG4A 2H8OA 3LG5A 4RXAA 3TS7A 4RYPA 3IPIA 5IVGA 4UMJA 1EZFA 3BNYA 5IMNA 3S9VA 3LK5A 4RXEA 5ERMA 5AYPA 5IK6A 4OMGA 2ONHA 4KQ5A 4JVJF 3N5HF 3WCBA 3OABA 1HXCA 2Z4WA 3UCAA 3KROA 4N9UA 5B02A 4KVDA 3WCGA 3WCLA 4F62A 4GP2A 4GP1A 2E94A 3P8LA 3G4DA 5B0MA 5IL8A 3TFPA 1VG6A 2E8XA 4LTVA 4LLTA 2Z50A 2AELA 5HN9A 4LXWA 1N24A 2VF6A 3NRIA 3LEEA 5IK0A 1N20A 3WCDA 4MC0A 3SDVA 5DJVF 4K10A 1HM4A 3ZOUA 2Z4ZA 3OACA 3Q30A 3CC9A 1UBWA 1VG7A 5C05A 3N46F 4FP4A 3M0GA 3SDQA 3M02A 4LLSA 3ICMA 5HNAA 3IBAA 3DYGA 1RQJA 4LA5A 3WJNA 1V4EA 4OKZA 4JZBA 3N0FA 4LPHF 3P41A 5CG5A 2AEKA 3VJ9A 4MC3A 2E92A 4RXCA 5JV2F 3ZL6A 3ZMCA 1UBVA 1YV5A 5IK9A 2Z7HA 3APZA 3Q1OA 3CP6A 1KIYA 3P8RA 1FPSA 4EA2A 2ZCRA 4OGUA 3EFQA 5DGSF 2I19A 5DJPF 5AFXA 5JA0F 3ZMBA 4H5CF 1RTRA 2E91A 5DZ2A 3WEHA 1HXGA 4KKMA 5A0KA 4OMHA 4LTZA 5JUZF 2Q9ZA 3KRFB 2F92F 5B0LA 2F9KF 3LOMA 3LSNA 4QXSF 3EGTA 3V66A 5DHKA 3VJDA 1VG3A 3RYEA 3SDUA 3P5RA 3LLWA 4P0VA 4RNQA 2Q9YA 2Z4VA 4LOBA 2Z4YA 3WEFA 5E8KA 3AE0A 3RMGA 4DHDA 3TFNA 5DJRF 2ZY1A 1WKZA 2ZCQA 1RQIA 4GAXA 3WSAA 3LGZB 3WEGA 2AZLA 2ZCSA 3N49F 5EASA 4KWDA 2ZEUA 3V1VA 2F94F 3ACWA 1HXAA 4E9UA 5EAUA 2DH4A 1YYUA 3AQ0A 3S4JA 3ZCDA 1JFGA 3AQCB 4E1EA 5IM1A 2OPNA 1YYRA 1N22A 3N5JF 1V4KA 2J1PA 3WEKA 3ID0A 5ILIA 4OKMA 5JV0F 3KRCB 1KIZA 3ADZA 4EA1A 4N1ZF 3N1VF 5ILYA 2Z4XA 3QKCA 1YHMA 4DZWA 5DHIA 4LUUA 2Z52A 1V4HA 3KRAB 4E9ZA 3QQVA 3P5PA 4PVYF 4NFJF 2AETA 3SDTA 5B00A 2QISA 3PDEA 4NFIF 5E8HA 4L2XF 3Q2QA 4MC8A 4ZQ8A 2ZEVA 3AQBB 2OA6A 5DGNF 4LFEA 2F7MF 1HX9A 5B0IA 4DWBA 2E8VA 4H5EF 4NUAA 4HD1A 4NG6A 4XQRF 5IL3A 3KBKA 1DI1A 4QPFA 2E90A 3NPRA 5EATA 3ICZA 4JYXA 4DXJA 3EZ3A 4KPDA 3KRAA 4P0XA 1V4JA 3RYWA 5JV1F 1N1BA 5KSXF 5B01A 3NF2A 3VJEA 3WCIA 3LJIA 4LZCA 1PS1A 5AELA 4KK2A 3LZ9A 3WE9A 1WL1A 2E8WA 3RBMA 5ILDA 5A0JA 5IN8A 5ILZA 4KPJA 5DGMF 4DWGA 3ACYA 4LZ3A 4KFAA 3WEIA 3V1XA 4NKFA 5B0KA 3N3DA 2P1CA 3TC1A 2PS5A 3LDWA 5ILHA 5B03A 2PS6A 2O1OA 3KROB 3N45F 1N21A 2RAHA 1WY0A 5IKAA 1UBXA 3G4FA 2OGDA 4KVYA 3PYAA 3KRPB 2PS4A 3KRFA 1N23A 3SDRA 3ICKA 3WCFA 4JXYA 1YYQA 3WCJA 5DIQF 3WEJA 4FJQA 4LPGF 4EA0A 1YJ4A 2E4OA 3OACB 3MAVA 4JZXA 3WCAA 3NPKA 3WSBA 3M01A 2Z78A 4KUXA 1WL0A 4LIXA 5EROA 3DYFA 2F89F 3WCMA 3WCHA 2E8UA 3SAEA 3Q2ZA 4KVIA 4Q23A 3PKOA 5ER8A 2FTZA 1VG2A 1N1ZA 1JFAA 3KRPA 3OYRA 1YHKA 2PS8A 4DI5A 5ILJA 4LZ0A 3M9UA 4NFKF 4PVXF 4KQUA 2J5CA 5IMIA 5HN7A 5ILKA 3ASXA 5AHUB 4GA3A 5B0JA 3LMDA 2F8CF 1YYTA 2AZJA 3VJCA 1UBYA 4LA6A 2Q58A 2ONGA 1V4IA 3KRCA 5DW7A 4LFGA 4JXNA 3M00A
chains in the Genus database with same CATH topology
1ZW5A 2OPMA 2Q80A 3DYHA 1YYSA 3VJ8A 4RXDA 4H5DF 4XQSF 3WC9A 3WJOA 3WJKA 3W7FA 3LGKA 2PS7A 2E95A 4F6XA 3ACXA 2EWGA 3N1WF 2F8ZF 3KB9A 2E93A 3ICNA 1WL2A 2FORA 1YQ7A 3MZVA 4KVWA 4DEMF 4XQTF 1HM7A 4KQSA 5IMPA 5HN8A 1YHLA 3BNXA 3PH7A 4WK5A 1DGPA 3N6KF 5A0IA 1WL3A 2J1OA 2ZCOA 3PYBA 4P0WA 5H9DA 5E8LA 4NKEA 3LVSA 4LFVF 2E8TA 3N3LF 3VJAA 3N0GA 3OABB 2AZKA 5I1UA 1WMWA 3VJBA 5CG6A 2Z7IA 3B7LA 4F6VA 5IKHA 5ERNA 3WCEA 3TFVA 3WCCA 3CKEA 1VG4A 2H8OA 3LG5A 4RXAA 3TS7A 4RYPA 3IPIA 5IVGA 4UMJA 1EZFA 3BNYA 5IMNA 3S9VA 3LK5A 4RXEA 5ERMA 5AYPA 5IK6A 4OMGA 2ONHA 4KQ5A 4JVJF 3N5HF 3WCBA 3OABA 1HXCA 2Z4WA 3UCAA 3KROA 4N9UA 5B02A 4KVDA 3WCGA 3WCLA 4F62A 4GP2A 4GP1A 2E94A 3P8LA 3G4DA 5B0MA 5IL8A 3TFPA 1VG6A 2E8XA 4LTVA 4LLTA 2Z50A 2AELA 5HN9A 4LXWA 1N24A 2VF6A 3NRIA 3LEEA 5IK0A 1N20A 3WCDA 4MC0A 3SDVA 5DJVF 4K10A 1HM4A 3ZOUA 2Z4ZA 3OACA 3Q30A 3CC9A 1UBWA 1VG7A 5C05A 3N46F 4FP4A 3M0GA 3SDQA 3M02A 4LLSA 3ICMA 5HNAA 3IBAA 3DYGA 1RQJA 4LA5A 3WJNA 1V4EA 4OKZA 4JZBA 3N0FA 4LPHF 3P41A 5CG5A 2AEKA 3VJ9A 4MC3A 2E92A 4RXCA 5JV2F 3ZL6A 3ZMCA 1UBVA 1YV5A 5IK9A 2Z7HA 3APZA 3Q1OA 3CP6A 1KIYA 3P8RA 1FPSA 4EA2A 2ZCRA 4OGUA 3EFQA 5DGSF 2I19A 5DJPF 5AFXA 5JA0F 3ZMBA 4H5CF 1RTRA 2E91A 5DZ2A 3WEHA 1HXGA 4KKMA 5A0KA 4OMHA 4LTZA 5JUZF 2Q9ZA 3KRFB 2F92F 5B0LA 2F9KF 3LOMA 3LSNA 4QXSF 3EGTA 3V66A 5DHKA 3VJDA 1VG3A 3RYEA 3SDUA 3P5RA 3LLWA 4P0VA 4RNQA 2Q9YA 2Z4VA 4LOBA 2Z4YA 3WEFA 5E8KA 3AE0A 3RMGA 4DHDA 3TFNA 5DJRF 2ZY1A 1WKZA 2ZCQA 1RQIA 4GAXA 3WSAA 3LGZB 3WEGA 2AZLA 2ZCSA 3N49F 5EASA 4KWDA 2ZEUA 3V1VA 2F94F 3ACWA 1HXAA 4E9UA 5EAUA 2DH4A 1YYUA 3AQ0A 3S4JA 3ZCDA 1JFGA 3AQCB 4E1EA 5IM1A 2OPNA 1YYRA 1N22A 3N5JF 1V4KA 2J1PA 3WEKA 3ID0A 5ILIA 4OKMA 5JV0F 3KRCB 1KIZA 3ADZA 4EA1A 4N1ZF 3N1VF 5ILYA 2Z4XA 3QKCA 1YHMA 4DZWA 5DHIA 4LUUA 2Z52A 1V4HA 3KRAB 4E9ZA 3QQVA 3P5PA 4PVYF 4NFJF 2AETA 3SDTA 5B00A 2QISA 3PDEA 4NFIF 5E8HA 4L2XF 3Q2QA 4MC8A 4ZQ8A 2ZEVA 3AQBB 2OA6A 5DGNF 4LFEA 2F7MF 1HX9A 5B0IA 4DWBA 2E8VA 4H5EF 4NUAA 4HD1A 4NG6A 4XQRF 5IL3A 3KBKA 1DI1A 4QPFA 2E90A 3NPRA 5EATA 3ICZA 4JYXA 4DXJA 3EZ3A 4KPDA 3KRAA 4P0XA 1V4JA 3RYWA 5JV1F 1N1BA 5KSXF 5B01A 3NF2A 3VJEA 3WCIA 3LJIA 4LZCA 1PS1A 5AELA 4KK2A 3LZ9A 3WE9A 1WL1A 2E8WA 3RBMA 5ILDA 5A0JA 5IN8A 5ILZA 4KPJA 5DGMF 4DWGA 3ACYA 4LZ3A 4KFAA 3WEIA 3V1XA 4NKFA 5B0KA 3N3DA 2P1CA 3TC1A 2PS5A 3LDWA 5ILHA 5B03A 2PS6A 2O1OA 3KROB 3N45F 1N21A 2RAHA 1WY0A 5IKAA 1UBXA 3G4FA 2OGDA 4KVYA 3PYAA 3KRPB 2PS4A 3KRFA 1N23A 3SDRA 3ICKA 3WCFA 4JXYA 1YYQA 3WCJA 5DIQF 3WEJA 4FJQA 4LPGF 4EA0A 1YJ4A 2E4OA 3OACB 3MAVA 4JZXA 3WCAA 3NPKA 3WSBA 3M01A 2Z78A 4KUXA 1WL0A 4LIXA 5EROA 3DYFA 2F89F 3WCMA 3WCHA 2E8UA 3SAEA 3Q2ZA 4KVIA 4Q23A 3PKOA 5ER8A 2FTZA 1VG2A 1N1ZA 1JFAA 3KRPA 3OYRA 1YHKA 2PS8A 4DI5A 5ILJA 4LZ0A 3M9UA 4NFKF 4PVXF 4KQUA 2J5CA 5IMIA 5HN7A 5ILKA 3ASXA 5AHUB 4GA3A 5B0JA 3LMDA 2F8CF 1YYTA 2AZJA 3VJCA 1UBYA 4LA6A 2Q58A 2ONGA 1V4IA 3KRCA 5DW7A 4LFGA 4JXNA 3M00A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZW5 A;  2OPM A;  2Q80 A;  3DYH A;  1YYS A;  3VJ8 A;  4RXD A;  4H5D F;  4XQS F;  3WC9 A;  3WJO A;  3WJK A;  3W7F A;  3LGK A;  2PS7 A;  2E95 A;  4F6X A;  3ACX A;  2EWG A;  3N1W F;  2F8Z F;  3KB9 A;  2E93 A;  3ICN A;  1WL2 A;  2FOR A;  1YQ7 A;  3MZV A;  4KVW A;  4DEM F;  4XQT F;  1HM7 A;  4KQS A;  5IMP A;  5HN8 A;  1YHL A;  3BNX A;  3PH7 A;  4WK5 A;  1DGP A;  3N6K F;  5A0I A;  1WL3 A;  2J1O A;  2ZCO A;  3PYB A;  4P0W A;  5H9D A;  5E8L A;  4NKE A;  3LVS A;  4LFV F;  2E8T A;  3N3L F;  3VJA A;  3N0G A;  3OAB B;  2AZK A;  5I1U A;  1WMW A;  3VJB A;  5CG6 A;  2Z7I A;  3B7L A;  4F6V A;  5IKH A;  5ERN A;  3WCE A;  3TFV A;  3WCC A;  3CKE A;  1VG4 A;  2H8O A;  3LG5 A;  4RXA A;  3TS7 A;  4RYP A;  3IPI A;  5IVG A;  4UMJ A;  1EZF A;  3BNY A;  5IMN A;  3S9V A;  3LK5 A;  4RXE A;  5ERM A;  5AYP A;  5IK6 A;  4OMG A;  2ONH A;  4KQ5 A;  4JVJ F;  3N5H F;  3WCB A;  3OAB A;  1HXC A;  2Z4W A;  3UCA A;  3KRO A;  4N9U A;  5B02 A;  4KVD A;  3WCG A;  3WCL A;  4F62 A;  4GP2 A;  4GP1 A;  2E94 A;  3P8L A;  3G4D A;  5B0M A;  5IL8 A;  3TFP A;  1VG6 A;  2E8X A;  4LTV A;  4LLT A;  2Z50 A;  2AEL A;  5HN9 A;  4LXW A;  1N24 A;  2VF6 A;  3NRI A;  3LEE A;  5IK0 A;  1N20 A;  3WCD A;  4MC0 A;  3SDV A;  5DJV F;  4K10 A;  1HM4 A;  3ZOU A;  2Z4Z A;  3OAC A;  3Q30 A;  3CC9 A;  1UBW A;  1VG7 A;  5C05 A;  3N46 F;  4FP4 A;  3M0G A;  3SDQ A;  3M02 A;  4LLS A;  3ICM A;  5HNA A;  3IBA A;  3DYG A;  1RQJ A;  4LA5 A;  3WJN A;  1V4E A;  4OKZ A;  4JZB A;  3N0F A;  4LPH F;  3P41 A;  5CG5 A;  2AEK A;  3VJ9 A;  4MC3 A;  2E92 A;  4RXC A;  5JV2 F;  3ZL6 A;  3ZMC A;  1UBV A;  1YV5 A;  5IK9 A;  2Z7H A;  3APZ A;  3Q1O A;  3CP6 A;  1KIY A;  3P8R A;  1FPS A;  4EA2 A;  2ZCR A;  4OGU A;  3EFQ A;  5DGS F;  2I19 A;  5DJP F;  5AFX A;  5JA0 F;  3ZMB A;  4H5C F;  1RTR A;  2E91 A;  5DZ2 A;  3WEH A;  1HXG A;  4KKM A;  5A0K A;  4OMH A;  4LTZ A;  5JUZ F;  2Q9Z A;  3KRF B;  2F92 F;  5B0L A;  2F9K F;  3LOM A;  3LSN A;  4QXS F;  3EGT A;  3V66 A;  5DHK A;  3VJD A;  1VG3 A;  3RYE A;  3SDU A;  3P5R A;  3LLW A;  4P0V A;  4RNQ A;  2Q9Y A;  2Z4V A;  4LOB A;  2Z4Y A;  3WEF A;  5E8K A;  3AE0 A;  3RMG A;  4DHD A;  3TFN A;  5DJR F;  2ZY1 A;  1WKZ A;  2ZCQ A;  1RQI A;  4GAX A;  3WSA A;  3LGZ B;  3WEG A;  2AZL A;  2ZCS A;  3N49 F;  5EAS A;  4KWD A;  2ZEU A;  3V1V A;  2F94 F;  3ACW A;  1HXA A;  4E9U A;  5EAU A;  2DH4 A;  1YYU A;  3AQ0 A;  3S4J A;  3ZCD A;  1JFG A;  3AQC B;  4E1E A;  5IM1 A;  2OPN A;  1YYR A;  1N22 A;  3N5J F;  1V4K A;  2J1P A;  3WEK A;  3ID0 A;  5ILI A;  4OKM A;  5JV0 F;  3KRC B;  1KIZ A;  3ADZ A;  4EA1 A;  4N1Z F;  3N1V F;  5ILY A;  2Z4X A;  3QKC A;  1YHM A;  4DZW A;  5DHI A;  4LUU A;  2Z52 A;  1V4H A;  3KRA B;  4E9Z A;  3QQV A;  3P5P A;  4PVY F;  4NFJ F;  2AET A;  3SDT A;  5B00 A;  2QIS A;  3PDE A;  4NFI F;  5E8H A;  4L2X F;  3Q2Q A;  4MC8 A;  4ZQ8 A;  2ZEV A;  3AQB B;  2OA6 A;  5DGN F;  4LFE A;  2F7M F;  1HX9 A;  5B0I A;  4DWB A;  2E8V A;  4H5E F;  4NUA A;  4HD1 A;  4NG6 A;  4XQR F;  5IL3 A;  3KBK A;  1DI1 A;  4QPF A;  2E90 A;  3NPR A;  5EAT A;  3ICZ A;  4JYX A;  4DXJ A;  3EZ3 A;  4KPD A;  3KRA A;  4P0X A;  1V4J A;  3RYW A;  5JV1 F;  1N1B A;  5KSX F;  5B01 A;  3NF2 A;  3VJE A;  3WCI A;  3LJI A;  4LZC A;  1PS1 A;  5AEL A;  4KK2 A;  3LZ9 A;  3WE9 A;  1WL1 A;  2E8W A;  3RBM A;  5ILD A;  5A0J A;  5IN8 A;  5ILZ A;  4KPJ A;  5DGM F;  4DWG A;  3ACY A;  4LZ3 A;  4KFA A;  3WEI A;  3V1X A;  4NKF A;  5B0K A;  3N3D A;  2P1C A;  3TC1 A;  2PS5 A;  3LDW A;  5ILH A;  5B03 A;  2PS6 A;  2O1O A;  3KRO B;  3N45 F;  1N21 A;  2RAH A;  1WY0 A;  5IKA A;  1UBX A;  3G4F A;  2OGD A;  4KVY A;  3PYA A;  3KRP B;  2PS4 A;  3KRF A;  1N23 A;  3SDR A;  3ICK A;  3WCF A;  4JXY A;  1YYQ A;  3WCJ A;  5DIQ F;  3WEJ A;  4FJQ A;  4LPG F;  4EA0 A;  1YJ4 A;  2E4O A;  3OAC B;  3MAV A;  4JZX A;  3WCA A;  3NPK A;  3WSB A;  3M01 A;  2Z78 A;  4KUX A;  1WL0 A;  4LIX A;  5ERO A;  3DYF A;  2F89 F;  3WCM A;  3WCH A;  2E8U A;  3SAE A;  3Q2Z A;  4KVI A;  4Q23 A;  3PKO A;  5ER8 A;  2FTZ A;  1VG2 A;  1N1Z A;  1JFA A;  3KRP A;  3OYR A;  1YHK A;  2PS8 A;  4DI5 A;  5ILJ A;  4LZ0 A;  3M9U A;  4NFK F;  4PVX F;  4KQU A;  2J5C A;  5IMI A;  5HN7 A;  5ILK A;  3ASX A;  5AHU B;  4GA3 A;  5B0J A;  3LMD A;  2F8C F;  1YYT A;  2AZJ A;  3VJC A;  1UBY A;  4LA6 A;  2Q58 A;  2ONG A;  1V4I A;  3KRC A;  5DW7 A;  4LFG A;  4JXN A;  3M00 A; 
#chains in the Genus database with same CATH topology
 1ZW5 A;  2OPM A;  2Q80 A;  3DYH A;  1YYS A;  3VJ8 A;  4RXD A;  4H5D F;  4XQS F;  3WC9 A;  3WJO A;  3WJK A;  3W7F A;  3LGK A;  2PS7 A;  2E95 A;  4F6X A;  3ACX A;  2EWG A;  3N1W F;  2F8Z F;  3KB9 A;  2E93 A;  3ICN A;  1WL2 A;  2FOR A;  1YQ7 A;  3MZV A;  4KVW A;  4DEM F;  4XQT F;  1HM7 A;  4KQS A;  5IMP A;  5HN8 A;  1YHL A;  3BNX A;  3PH7 A;  4WK5 A;  1DGP A;  3N6K F;  5A0I A;  1WL3 A;  2J1O A;  2ZCO A;  3PYB A;  4P0W A;  5H9D A;  5E8L A;  4NKE A;  3LVS A;  4LFV F;  2E8T A;  3N3L F;  3VJA A;  3N0G A;  3OAB B;  2AZK A;  5I1U A;  1WMW A;  3VJB A;  5CG6 A;  2Z7I A;  3B7L A;  4F6V A;  5IKH A;  5ERN A;  3WCE A;  3TFV A;  3WCC A;  3CKE A;  1VG4 A;  2H8O A;  3LG5 A;  4RXA A;  3TS7 A;  4RYP A;  3IPI A;  5IVG A;  4UMJ A;  1EZF A;  3BNY A;  5IMN A;  3S9V A;  3LK5 A;  4RXE A;  5ERM A;  5AYP A;  5IK6 A;  4OMG A;  2ONH A;  4KQ5 A;  4JVJ F;  3N5H F;  3WCB A;  3OAB A;  1HXC A;  2Z4W A;  3UCA A;  3KRO A;  4N9U A;  5B02 A;  4KVD A;  3WCG A;  3WCL A;  4F62 A;  4GP2 A;  4GP1 A;  2E94 A;  3P8L A;  3G4D A;  5B0M A;  5IL8 A;  3TFP A;  1VG6 A;  2E8X A;  4LTV A;  4LLT A;  2Z50 A;  2AEL A;  5HN9 A;  4LXW A;  1N24 A;  2VF6 A;  3NRI A;  3LEE A;  5IK0 A;  1N20 A;  3WCD A;  4MC0 A;  3SDV A;  5DJV F;  4K10 A;  1HM4 A;  3ZOU A;  2Z4Z A;  3OAC A;  3Q30 A;  3CC9 A;  1UBW A;  1VG7 A;  5C05 A;  3N46 F;  4FP4 A;  3M0G A;  3SDQ A;  3M02 A;  4LLS A;  3ICM A;  5HNA A;  3IBA A;  3DYG A;  1RQJ A;  4LA5 A;  3WJN A;  1V4E A;  4OKZ A;  4JZB A;  3N0F A;  4LPH F;  3P41 A;  5CG5 A;  2AEK A;  3VJ9 A;  4MC3 A;  2E92 A;  4RXC A;  5JV2 F;  3ZL6 A;  3ZMC A;  1UBV A;  1YV5 A;  5IK9 A;  2Z7H A;  3APZ A;  3Q1O A;  3CP6 A;  1KIY A;  3P8R A;  1FPS A;  4EA2 A;  2ZCR A;  4OGU A;  3EFQ A;  5DGS F;  2I19 A;  5DJP F;  5AFX A;  5JA0 F;  3ZMB A;  4H5C F;  1RTR A;  2E91 A;  5DZ2 A;  3WEH A;  1HXG A;  4KKM A;  5A0K A;  4OMH A;  4LTZ A;  5JUZ F;  2Q9Z A;  3KRF B;  2F92 F;  5B0L A;  2F9K F;  3LOM A;  3LSN A;  4QXS F;  3EGT A;  3V66 A;  5DHK A;  3VJD A;  1VG3 A;  3RYE A;  3SDU A;  3P5R A;  3LLW A;  4P0V A;  4RNQ A;  2Q9Y A;  2Z4V A;  4LOB A;  2Z4Y A;  3WEF A;  5E8K A;  3AE0 A;  3RMG A;  4DHD A;  3TFN A;  5DJR F;  2ZY1 A;  1WKZ A;  2ZCQ A;  1RQI A;  4GAX A;  3WSA A;  3LGZ B;  3WEG A;  2AZL A;  2ZCS A;  3N49 F;  5EAS A;  4KWD A;  2ZEU A;  3V1V A;  2F94 F;  3ACW A;  1HXA A;  4E9U A;  5EAU A;  2DH4 A;  1YYU A;  3AQ0 A;  3S4J A;  3ZCD A;  1JFG A;  3AQC B;  4E1E A;  5IM1 A;  2OPN A;  1YYR A;  1N22 A;  3N5J F;  1V4K A;  2J1P A;  3WEK A;  3ID0 A;  5ILI A;  4OKM A;  5JV0 F;  3KRC B;  1KIZ A;  3ADZ A;  4EA1 A;  4N1Z F;  3N1V F;  5ILY A;  2Z4X A;  3QKC A;  1YHM A;  4DZW A;  5DHI A;  4LUU A;  2Z52 A;  1V4H A;  3KRA B;  4E9Z A;  3QQV A;  3P5P A;  4PVY F;  4NFJ F;  2AET A;  3SDT A;  5B00 A;  2QIS A;  3PDE A;  4NFI F;  5E8H A;  4L2X F;  3Q2Q A;  4MC8 A;  4ZQ8 A;  2ZEV A;  3AQB B;  2OA6 A;  5DGN F;  4LFE A;  2F7M F;  1HX9 A;  5B0I A;  4DWB A;  2E8V A;  4H5E F;  4NUA A;  4HD1 A;  4NG6 A;  4XQR F;  5IL3 A;  3KBK A;  1DI1 A;  4QPF A;  2E90 A;  3NPR A;  5EAT A;  3ICZ A;  4JYX A;  4DXJ A;  3EZ3 A;  4KPD A;  3KRA A;  4P0X A;  1V4J A;  3RYW A;  5JV1 F;  1N1B A;  5KSX F;  5B01 A;  3NF2 A;  3VJE A;  3WCI A;  3LJI A;  4LZC A;  1PS1 A;  5AEL A;  4KK2 A;  3LZ9 A;  3WE9 A;  1WL1 A;  2E8W A;  3RBM A;  5ILD A;  5A0J A;  5IN8 A;  5ILZ A;  4KPJ A;  5DGM F;  4DWG A;  3ACY A;  4LZ3 A;  4KFA A;  3WEI A;  3V1X A;  4NKF A;  5B0K A;  3N3D A;  2P1C A;  3TC1 A;  2PS5 A;  3LDW A;  5ILH A;  5B03 A;  2PS6 A;  2O1O A;  3KRO B;  3N45 F;  1N21 A;  2RAH A;  1WY0 A;  5IKA A;  1UBX A;  3G4F A;  2OGD A;  4KVY A;  3PYA A;  3KRP B;  2PS4 A;  3KRF A;  1N23 A;  3SDR A;  3ICK A;  3WCF A;  4JXY A;  1YYQ A;  3WCJ A;  5DIQ F;  3WEJ A;  4FJQ A;  4LPG F;  4EA0 A;  1YJ4 A;  2E4O A;  3OAC B;  3MAV A;  4JZX A;  3WCA A;  3NPK A;  3WSB A;  3M01 A;  2Z78 A;  4KUX A;  1WL0 A;  4LIX A;  5ERO A;  3DYF A;  2F89 F;  3WCM A;  3WCH A;  2E8U A;  3SAE A;  3Q2Z A;  4KVI A;  4Q23 A;  3PKO A;  5ER8 A;  2FTZ A;  1VG2 A;  1N1Z A;  1JFA A;  3KRP A;  3OYR A;  1YHK A;  2PS8 A;  4DI5 A;  5ILJ A;  4LZ0 A;  3M9U A;  4NFK F;  4PVX F;  4KQU A;  2J5C A;  5IMI A;  5HN7 A;  5ILK A;  3ASX A;  5AHU B;  4GA3 A;  5B0J A;  3LMD A;  2F8C F;  1YYT A;  2AZJ A;  3VJC A;  1UBY A;  4LA6 A;  2Q58 A;  2ONG A;  1V4I A;  3KRC A;  5DW7 A;  4LFG A;  4JXN A;  3M00 A; 
#chains in the Genus database with same CATH homology
 1ZW5 A;  2OPM A;  2Q80 A;  3DYH A;  1YYS A;  3VJ8 A;  4RXD A;  4H5D F;  4XQS F;  3WC9 A;  3WJO A;  3WJK A;  3W7F A;  3LGK A;  2PS7 A;  2E95 A;  4F6X A;  3ACX A;  2EWG A;  3N1W F;  2F8Z F;  3KB9 A;  2E93 A;  3ICN A;  1WL2 A;  2FOR A;  1YQ7 A;  3MZV A;  4KVW A;  4DEM F;  4XQT F;  1HM7 A;  4KQS A;  5IMP A;  5HN8 A;  1YHL A;  3BNX A;  3PH7 A;  4WK5 A;  1DGP A;  3N6K F;  5A0I A;  1WL3 A;  2J1O A;  2ZCO A;  3PYB A;  4P0W A;  5H9D A;  5E8L A;  4NKE A;  3LVS A;  4LFV F;  2E8T A;  3N3L F;  3VJA A;  3N0G A;  3OAB B;  2AZK A;  5I1U A;  1WMW A;  3VJB A;  5CG6 A;  2Z7I A;  3B7L A;  4F6V A;  5IKH A;  5ERN A;  3WCE A;  3TFV A;  3WCC A;  3CKE A;  1VG4 A;  2H8O A;  3LG5 A;  4RXA A;  3TS7 A;  4RYP A;  3IPI A;  5IVG A;  4UMJ A;  1EZF A;  3BNY A;  5IMN A;  3S9V A;  3LK5 A;  4RXE A;  5ERM A;  5AYP A;  5IK6 A;  4OMG A;  2ONH A;  4KQ5 A;  4JVJ F;  3N5H F;  3WCB A;  3OAB A;  1HXC A;  2Z4W A;  3UCA A;  3KRO A;  4N9U A;  5B02 A;  4KVD A;  3WCG A;  3WCL A;  4F62 A;  4GP2 A;  4GP1 A;  2E94 A;  3P8L A;  3G4D A;  5B0M A;  5IL8 A;  3TFP A;  1VG6 A;  2E8X A;  4LTV A;  4LLT A;  2Z50 A;  2AEL A;  5HN9 A;  4LXW A;  1N24 A;  2VF6 A;  3NRI A;  3LEE A;  5IK0 A;  1N20 A;  3WCD A;  4MC0 A;  3SDV A;  5DJV F;  4K10 A;  1HM4 A;  3ZOU A;  2Z4Z A;  3OAC A;  3Q30 A;  3CC9 A;  1UBW A;  1VG7 A;  5C05 A;  3N46 F;  4FP4 A;  3M0G A;  3SDQ A;  3M02 A;  4LLS A;  3ICM A;  5HNA A;  3IBA A;  3DYG A;  1RQJ A;  4LA5 A;  3WJN A;  1V4E A;  4OKZ A;  4JZB A;  3N0F A;  4LPH F;  3P41 A;  5CG5 A;  2AEK A;  3VJ9 A;  4MC3 A;  2E92 A;  4RXC A;  5JV2 F;  3ZL6 A;  3ZMC A;  1UBV A;  1YV5 A;  5IK9 A;  2Z7H A;  3APZ A;  3Q1O A;  3CP6 A;  1KIY A;  3P8R A;  1FPS A;  4EA2 A;  2ZCR A;  4OGU A;  3EFQ A;  5DGS F;  2I19 A;  5DJP F;  5AFX A;  5JA0 F;  3ZMB A;  4H5C F;  1RTR A;  2E91 A;  5DZ2 A;  3WEH A;  1HXG A;  4KKM A;  5A0K A;  4OMH A;  4LTZ A;  5JUZ F;  2Q9Z A;  3KRF B;  2F92 F;  5B0L A;  2F9K F;  3LOM A;  3LSN A;  4QXS F;  3EGT A;  3V66 A;  5DHK A;  3VJD A;  1VG3 A;  3RYE A;  3SDU A;  3P5R A;  3LLW A;  4P0V A;  4RNQ A;  2Q9Y A;  2Z4V A;  4LOB A;  2Z4Y A;  3WEF A;  5E8K A;  3AE0 A;  3RMG A;  4DHD A;  3TFN A;  5DJR F;  2ZY1 A;  1WKZ A;  2ZCQ A;  1RQI A;  4GAX A;  3WSA A;  3LGZ B;  3WEG A;  2AZL A;  2ZCS A;  3N49 F;  5EAS A;  4KWD A;  2ZEU A;  3V1V A;  2F94 F;  3ACW A;  1HXA A;  4E9U A;  5EAU A;  2DH4 A;  1YYU A;  3AQ0 A;  3S4J A;  3ZCD A;  1JFG A;  3AQC B;  4E1E A;  5IM1 A;  2OPN A;  1YYR A;  1N22 A;  3N5J F;  1V4K A;  2J1P A;  3WEK A;  3ID0 A;  5ILI A;  4OKM A;  5JV0 F;  3KRC B;  1KIZ A;  3ADZ A;  4EA1 A;  4N1Z F;  3N1V F;  5ILY A;  2Z4X A;  3QKC A;  1YHM A;  4DZW A;  5DHI A;  4LUU A;  2Z52 A;  1V4H A;  3KRA B;  4E9Z A;  3QQV A;  3P5P A;  4PVY F;  4NFJ F;  2AET A;  3SDT A;  5B00 A;  2QIS A;  3PDE A;  4NFI F;  5E8H A;  4L2X F;  3Q2Q A;  4MC8 A;  4ZQ8 A;  2ZEV A;  3AQB B;  2OA6 A;  5DGN F;  4LFE A;  2F7M F;  1HX9 A;  5B0I A;  4DWB A;  2E8V A;  4H5E F;  4NUA A;  4HD1 A;  4NG6 A;  4XQR F;  5IL3 A;  3KBK A;  1DI1 A;  4QPF A;  2E90 A;  3NPR A;  5EAT A;  3ICZ A;  4JYX A;  4DXJ A;  3EZ3 A;  4KPD A;  3KRA A;  4P0X A;  1V4J A;  3RYW A;  5JV1 F;  1N1B A;  5KSX F;  5B01 A;  3NF2 A;  3VJE A;  3WCI A;  3LJI A;  4LZC A;  1PS1 A;  5AEL A;  4KK2 A;  3LZ9 A;  3WE9 A;  1WL1 A;  2E8W A;  3RBM A;  5ILD A;  5A0J A;  5IN8 A;  5ILZ A;  4KPJ A;  5DGM F;  4DWG A;  3ACY A;  4LZ3 A;  4KFA A;  3WEI A;  3V1X A;  4NKF A;  5B0K A;  3N3D A;  2P1C A;  3TC1 A;  2PS5 A;  3LDW A;  5ILH A;  5B03 A;  2PS6 A;  2O1O A;  3KRO B;  3N45 F;  1N21 A;  2RAH A;  1WY0 A;  5IKA A;  1UBX A;  3G4F A;  2OGD A;  4KVY A;  3PYA A;  3KRP B;  2PS4 A;  3KRF A;  1N23 A;  3SDR A;  3ICK A;  3WCF A;  4JXY A;  1YYQ A;  3WCJ A;  5DIQ F;  3WEJ A;  4FJQ A;  4LPG F;  4EA0 A;  1YJ4 A;  2E4O A;  3OAC B;  3MAV A;  4JZX A;  3WCA A;  3NPK A;  3WSB A;  3M01 A;  2Z78 A;  4KUX A;  1WL0 A;  4LIX A;  5ERO A;  3DYF A;  2F89 F;  3WCM A;  3WCH A;  2E8U A;  3SAE A;  3Q2Z A;  4KVI A;  4Q23 A;  3PKO A;  5ER8 A;  2FTZ A;  1VG2 A;  1N1Z A;  1JFA A;  3KRP A;  3OYR A;  1YHK A;  2PS8 A;  4DI5 A;  5ILJ A;  4LZ0 A;  3M9U A;  4NFK F;  4PVX F;  4KQU A;  2J5C A;  5IMI A;  5HN7 A;  5ILK A;  3ASX A;  5AHU B;  4GA3 A;  5B0J A;  3LMD A;  2F8C F;  1YYT A;  2AZJ A;  3VJC A;  1UBY A;  4LA6 A;  2Q58 A;  2ONG A;  1V4I A;  3KRC A;  5DW7 A;  4LFG A;  4JXN A;  3M00 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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