4P0VA

Crystal structure of human farnesyl diphosphoate synthase in complex with zoledronate and taxodione
Total Genus 137
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
346
structure length
346
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
molecule keywords Farnesyl pyrophosphate synthase
publication title Taxodione and arenarone inhibit farnesyl diphosphate synthase by binding to the isopentenyl diphosphate site.
pubmed doi rcsb
source organism Homo sapiens
total genus 137
structure length 346
sequence length 346
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2014-02-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4p0vA00
3M00A 5B0JA 3ZL6A 3NPKA 5DHKA 4QXSF 2Z4ZA 3KRCB 3LG5A 4LIXA 5JV2F 3N49F 3V66A 5IM1A 4DEMF 1V4KA 2ZCOA 3WSBA 3N5JF 3KRFB 3NF2A 2PS7A 1VG6A 3KROA 2RAHA 5A0KA 4XQRF 1DGPA 4KVWA 4JXNA 3KRAA 4RYPA 1WL2A 5DGNF 4WK5A 5ERMA 3WCIA 2I19A 4GP2A 5AFXA 2ZEVA 4K10A 1N20A 3VJCA 1N22A 3LVSA 4OKZA 3WC9A 3WEFA 4L2XF 1PS1A 3G4DA 2E92A 1UBYA 3ASXA 3RYWA 3WCAA 2E8WA 2H8OA 4LFEA 3WCFA 2F89F 2Q58A 1WL3A 2F8CF 3KROB 3AQBB 2E8TA 2OPNA 4LZCA 3UCAA 1N24A 1N1BA 2O1OA 2J1PA 1WL0A 3Q2ZA 2F94F 5B00A 3LDWA 3NPRA 4LPGF 4F6XA 3KRCA 4DXJA 2AETA 5ILKA 5ILHA 3ZCDA 1YHKA 5CG5A 3SAEA 1YHMA 4LFVF 3WEKA 5HN7A 2ZCQA 3SDRA 1RQJA 4LZ3A 2E8VA 3KRFA 3P8RA 4MC0A 2P1CA 3P5PA 2Q9YA 5JA0F 4HD1A 5HN9A 4XQTF 4GAXA 1YJ4A 5AHUB 3WCBA 5ILIA 3PDEA 4JZBA 4LXWA 3ACWA 2F92F 4P0WA 5ERNA 3VJAA 4RXDA 4F62A 2E8XA 3PYBA 3TC1A 4XQSF 1V4HA 2F7MF 4KVDA 3N46F 1RQIA 5B01A 2FTZA 3P41A 2AZKA 4H5DF 4LTZA 2Z7IA 3N45F 3M9UA 4LA5A 3WE9A 4KUXA 4F6VA 5ILZA 4FP4A 5AYPA 3N3LF 3TFNA 3EZ3A 3OABB 5IL8A 4RXAA 3PH7A 1UBVA 5ILYA 5ILDA 3LZ9A 3WEGA 4LUUA 1YYTA 4OMHA 4LZ0A 5IK9A 5E8LA 3AQCB 3AQ0A 3N0GA 4MC3A 5E8HA 3WCLA 3M01A 5IN8A 1UBXA 4KQ5A 4UMJA 3VJDA 2DH4A 5IL3A 1WMWA 3LGKA 3LGZB 1WKZA 3PYAA 3SDVA 3V1XA 3S9VA 4JZXA 3PKOA 3ZOUA 4DZWA 4EA0A 1V4EA 2ZCRA 5IK6A 4N1ZF 3CKEA 5ER8A 2Q80A 2Z4WA 4DI5A 3VJ9A 5IMIA 4OMGA 4E9UA 5A0IA 4EA2A 3LLWA 3P5RA 3DYHA 2E91A 3IPIA 4JYXA 4H5CF 1HM7A 5DIQF 3P8LA 3VJEA 5DW7A 3KB9A 1N21A 3WCEA 3Q2QA 3ICMA 5JV1F 5CG6A 4LOBA 1N1ZA 3ZMCA 3ID0A 5H9DA 4DWBA 4P0XA 2OPMA 4JVJF 5DGMF 4Q23A 3OABA 2Z7HA 2Z4YA 4KK2A 3RYEA 3TFVA 3MZVA 3S4JA 1KIYA 4GP1A 3LJIA 1FPSA 3ZMBA 3EFQA 3CP6A 3W7FA 2ONHA 2PS4A 3LK5A 3OACA 4KFAA 3WSAA 3N6KF 2Z52A 5KSXF 1V4JA 3KRPB 1YYUA 2Z4VA 1YHLA 4NFJF 3WJKA 4KPDA 5EROA 2ZCSA 5I1UA 3RBMA 1HX9A 3LSNA 2Q9ZA 3VJBA 5B03A 4DHDA 5B0MA 4KVYA 3NRIA 3MAVA 3WCDA 1V4IA 2AEKA 3LEEA 5B0LA 3N0FA 5B02A 5EASA 3CC9A 4OKMA 2E4OA 4RNQA 3M02A 2AZJA 1N23A 3BNXA 2PS8A 3IBAA 5IKAA 2F8ZF 4NKFA 3N3DA 1KIZA 4QPFA 1VG3A 3OACB 3WCMA 5DJRF 2E94A 4PVYF 4LLSA 2PS5A 4LA6A 4RXCA 5EAUA 3ACYA 4ZQ8A 1WL1A 5HNAA 2Z4XA 1EZFA 5DHIA 3WCHA 5B0KA 5IK0A 1HXAA 4GA3A 3WCCA 3N5HF 5DZ2A 1HM4A 1WY0A 5A0JA 2J1OA 3WEJA 3BNYA 2E93A 2QISA 4KPJA 5JUZF 3AE0A 2E95A 5IMPA 5EATA 4LTVA 5DJPF 1JFAA 4KKMA 3WEIA 2VF6A 5B0IA 3WJOA 1YV5A 2E90A 3WCGA 2AELA 3KRPA 2Z78A 3LOMA 3Q1OA 5DGSF 3DYFA 5C05A 2ZY1A 3SDUA 4LPHF 5IMNA 4H5EF 4KVIA 4NKEA 1VG4A 2OA6A 3OYRA 4NFIF 3ACXA 2OGDA 5AELA 1YYQA 4FJQA 5IVGA 4E9ZA 3APZA 1JFGA 1YYSA 4RXEA 5E8KA 3RMGA 3SDQA 3EGTA 3ICNA 2PS6A 3QKCA 2Z50A 1YYRA 4P0VA 4PVXF 1VG2A 2ONGA 3M0GA 4KQSA 1HXGA 4KQUA 1RTRA 1DI1A 2AZLA 4KWDA 3V1VA 1UBWA 3QQVA 3KRAB 2F9KF 3ICKA 1YQ7A 4OGUA 1ZW5A 3WEHA 4JXYA 3ADZA 4LLTA 3ICZA 3DYGA 3VJ8A 3TS7A 4EA1A 4NG6A 3B7LA 5IKHA 3TFPA 4LFGA 4MC8A 5DJVF 2FORA 2EWGA 3SDTA 5ILJA 2ZEUA 4N9UA 2E8UA 4E1EA 1VG7A 5JV0F 4NUAA 2J5CA 3Q30A 3G4FA 4NFKF 5HN8A 3KBKA 1HXCA 4DWGA 3WCJA 3N1VF 3LMDA 3WJNA 3N1WF
chains in the Genus database with same CATH superfamily
3M00A 5B0JA 3ZL6A 3NPKA 5DHKA 4QXSF 2Z4ZA 3KRCB 3LG5A 4LIXA 5JV2F 3N49F 3V66A 5IM1A 4DEMF 1V4KA 2ZCOA 3WSBA 3N5JF 3KRFB 3NF2A 2PS7A 1VG6A 3KROA 2RAHA 5A0KA 4XQRF 1DGPA 4KVWA 4JXNA 3KRAA 4RYPA 1WL2A 5DGNF 4WK5A 5ERMA 3WCIA 2I19A 4GP2A 5AFXA 2ZEVA 4K10A 1N20A 3VJCA 1N22A 3LVSA 4OKZA 3WC9A 3WEFA 4L2XF 1PS1A 3G4DA 2E92A 1UBYA 3ASXA 3RYWA 3WCAA 2E8WA 2H8OA 4LFEA 3WCFA 2F89F 2Q58A 1WL3A 2F8CF 3KROB 3AQBB 2E8TA 2OPNA 4LZCA 3UCAA 1N24A 1N1BA 2O1OA 2J1PA 1WL0A 3Q2ZA 2F94F 5B00A 3LDWA 3NPRA 4LPGF 4F6XA 3KRCA 4DXJA 2AETA 5ILKA 5ILHA 3ZCDA 1YHKA 5CG5A 3SAEA 1YHMA 4LFVF 3WEKA 5HN7A 2ZCQA 3SDRA 1RQJA 4LZ3A 2E8VA 3KRFA 3P8RA 4MC0A 2P1CA 3P5PA 2Q9YA 5JA0F 4HD1A 5HN9A 4XQTF 4GAXA 1YJ4A 5AHUB 3WCBA 5ILIA 3PDEA 4JZBA 4LXWA 3ACWA 2F92F 4P0WA 5ERNA 3VJAA 4RXDA 4F62A 2E8XA 3PYBA 3TC1A 4XQSF 1V4HA 2F7MF 4KVDA 3N46F 1RQIA 5B01A 2FTZA 3P41A 2AZKA 4H5DF 4LTZA 2Z7IA 3N45F 3M9UA 4LA5A 3WE9A 4KUXA 4F6VA 5ILZA 4FP4A 5AYPA 3N3LF 3TFNA 3EZ3A 3OABB 5IL8A 4RXAA 3PH7A 1UBVA 5ILYA 5ILDA 3LZ9A 3WEGA 4LUUA 1YYTA 4OMHA 4LZ0A 5IK9A 5E8LA 3AQCB 3AQ0A 3N0GA 4MC3A 5E8HA 3WCLA 3M01A 5IN8A 1UBXA 4KQ5A 4UMJA 3VJDA 2DH4A 5IL3A 1WMWA 3LGKA 3LGZB 1WKZA 3PYAA 3SDVA 3V1XA 3S9VA 4JZXA 3PKOA 3ZOUA 4DZWA 4EA0A 1V4EA 2ZCRA 5IK6A 4N1ZF 3CKEA 5ER8A 2Q80A 2Z4WA 4DI5A 3VJ9A 5IMIA 4OMGA 4E9UA 5A0IA 4EA2A 3LLWA 3P5RA 3DYHA 2E91A 3IPIA 4JYXA 4H5CF 1HM7A 5DIQF 3P8LA 3VJEA 5DW7A 3KB9A 1N21A 3WCEA 3Q2QA 3ICMA 5JV1F 5CG6A 4LOBA 1N1ZA 3ZMCA 3ID0A 5H9DA 4DWBA 4P0XA 2OPMA 4JVJF 5DGMF 4Q23A 3OABA 2Z7HA 2Z4YA 4KK2A 3RYEA 3TFVA 3MZVA 3S4JA 1KIYA 4GP1A 3LJIA 1FPSA 3ZMBA 3EFQA 3CP6A 3W7FA 2ONHA 2PS4A 3LK5A 3OACA 4KFAA 3WSAA 3N6KF 2Z52A 5KSXF 1V4JA 3KRPB 1YYUA 2Z4VA 1YHLA 4NFJF 3WJKA 4KPDA 5EROA 2ZCSA 5I1UA 3RBMA 1HX9A 3LSNA 2Q9ZA 3VJBA 5B03A 4DHDA 5B0MA 4KVYA 3NRIA 3MAVA 3WCDA 1V4IA 2AEKA 3LEEA 5B0LA 3N0FA 5B02A 5EASA 3CC9A 4OKMA 2E4OA 4RNQA 3M02A 2AZJA 1N23A 3BNXA 2PS8A 3IBAA 5IKAA 2F8ZF 4NKFA 3N3DA 1KIZA 4QPFA 1VG3A 3OACB 3WCMA 5DJRF 2E94A 4PVYF 4LLSA 2PS5A 4LA6A 4RXCA 5EAUA 3ACYA 4ZQ8A 1WL1A 5HNAA 2Z4XA 1EZFA 5DHIA 3WCHA 5B0KA 5IK0A 1HXAA 4GA3A 3WCCA 3N5HF 5DZ2A 1HM4A 1WY0A 5A0JA 2J1OA 3WEJA 3BNYA 2E93A 2QISA 4KPJA 5JUZF 3AE0A 2E95A 5IMPA 5EATA 4LTVA 5DJPF 1JFAA 4KKMA 3WEIA 2VF6A 5B0IA 3WJOA 1YV5A 2E90A 3WCGA 2AELA 3KRPA 2Z78A 3LOMA 3Q1OA 5DGSF 3DYFA 5C05A 2ZY1A 3SDUA 4LPHF 5IMNA 4H5EF 4KVIA 4NKEA 1VG4A 2OA6A 3OYRA 4NFIF 3ACXA 2OGDA 5AELA 1YYQA 4FJQA 5IVGA 4E9ZA 3APZA 1JFGA 1YYSA 4RXEA 5E8KA 3RMGA 3SDQA 3EGTA 3ICNA 2PS6A 3QKCA 2Z50A 1YYRA 4P0VA 4PVXF 1VG2A 2ONGA 3M0GA 4KQSA 1HXGA 4KQUA 1RTRA 1DI1A 2AZLA 4KWDA 3V1VA 1UBWA 3QQVA 3KRAB 2F9KF 3ICKA 1YQ7A 4OGUA 1ZW5A 3WEHA 4JXYA 3ADZA 4LLTA 3ICZA 3DYGA 3VJ8A 3TS7A 4EA1A 4NG6A 3B7LA 5IKHA 3TFPA 4LFGA 4MC8A 5DJVF 2FORA 2EWGA 3SDTA 5ILJA 2ZEUA 4N9UA 2E8UA 4E1EA 1VG7A 5JV0F 4NUAA 2J5CA 3Q30A 3G4FA 4NFKF 5HN8A 3KBKA 1HXCA 4DWGA 3WCJA 3N1VF 3LMDA 3WJNA 3N1WF
chains in the Genus database with same CATH topology
3M00A 5B0JA 3ZL6A 3NPKA 5DHKA 4QXSF 2Z4ZA 3KRCB 3LG5A 4LIXA 5JV2F 3N49F 3V66A 5IM1A 4DEMF 1V4KA 2ZCOA 3WSBA 3N5JF 3KRFB 3NF2A 2PS7A 1VG6A 3KROA 2RAHA 5A0KA 4XQRF 1DGPA 4KVWA 4JXNA 3KRAA 4RYPA 1WL2A 5DGNF 4WK5A 5ERMA 3WCIA 2I19A 4GP2A 5AFXA 2ZEVA 4K10A 1N20A 3VJCA 1N22A 3LVSA 4OKZA 3WC9A 3WEFA 4L2XF 1PS1A 3G4DA 2E92A 1UBYA 3ASXA 3RYWA 3WCAA 2E8WA 2H8OA 4LFEA 3WCFA 2F89F 2Q58A 1WL3A 2F8CF 3KROB 3AQBB 2E8TA 2OPNA 4LZCA 3UCAA 1N24A 1N1BA 2O1OA 2J1PA 1WL0A 3Q2ZA 2F94F 5B00A 3LDWA 3NPRA 4LPGF 4F6XA 3KRCA 4DXJA 2AETA 5ILKA 5ILHA 3ZCDA 1YHKA 5CG5A 3SAEA 1YHMA 4LFVF 3WEKA 5HN7A 2ZCQA 3SDRA 1RQJA 4LZ3A 2E8VA 3KRFA 3P8RA 4MC0A 2P1CA 3P5PA 2Q9YA 5JA0F 4HD1A 5HN9A 4XQTF 4GAXA 1YJ4A 5AHUB 3WCBA 5ILIA 3PDEA 4JZBA 4LXWA 3ACWA 2F92F 4P0WA 5ERNA 3VJAA 4RXDA 4F62A 2E8XA 3PYBA 3TC1A 4XQSF 1V4HA 2F7MF 4KVDA 3N46F 1RQIA 5B01A 2FTZA 3P41A 2AZKA 4H5DF 4LTZA 2Z7IA 3N45F 3M9UA 4LA5A 3WE9A 4KUXA 4F6VA 5ILZA 4FP4A 5AYPA 3N3LF 3TFNA 3EZ3A 3OABB 5IL8A 4RXAA 3PH7A 1UBVA 5ILYA 5ILDA 3LZ9A 3WEGA 4LUUA 1YYTA 4OMHA 4LZ0A 5IK9A 5E8LA 3AQCB 3AQ0A 3N0GA 4MC3A 5E8HA 3WCLA 3M01A 5IN8A 1UBXA 4KQ5A 4UMJA 3VJDA 2DH4A 5IL3A 1WMWA 3LGKA 3LGZB 1WKZA 3PYAA 3SDVA 3V1XA 3S9VA 4JZXA 3PKOA 3ZOUA 4DZWA 4EA0A 1V4EA 2ZCRA 5IK6A 4N1ZF 3CKEA 5ER8A 2Q80A 2Z4WA 4DI5A 3VJ9A 5IMIA 4OMGA 4E9UA 5A0IA 4EA2A 3LLWA 3P5RA 3DYHA 2E91A 3IPIA 4JYXA 4H5CF 1HM7A 5DIQF 3P8LA 3VJEA 5DW7A 3KB9A 1N21A 3WCEA 3Q2QA 3ICMA 5JV1F 5CG6A 4LOBA 1N1ZA 3ZMCA 3ID0A 5H9DA 4DWBA 4P0XA 2OPMA 4JVJF 5DGMF 4Q23A 3OABA 2Z7HA 2Z4YA 4KK2A 3RYEA 3TFVA 3MZVA 3S4JA 1KIYA 4GP1A 3LJIA 1FPSA 3ZMBA 3EFQA 3CP6A 3W7FA 2ONHA 2PS4A 3LK5A 3OACA 4KFAA 3WSAA 3N6KF 2Z52A 5KSXF 1V4JA 3KRPB 1YYUA 2Z4VA 1YHLA 4NFJF 3WJKA 4KPDA 5EROA 2ZCSA 5I1UA 3RBMA 1HX9A 3LSNA 2Q9ZA 3VJBA 5B03A 4DHDA 5B0MA 4KVYA 3NRIA 3MAVA 3WCDA 1V4IA 2AEKA 3LEEA 5B0LA 3N0FA 5B02A 5EASA 3CC9A 4OKMA 2E4OA 4RNQA 3M02A 2AZJA 1N23A 3BNXA 2PS8A 3IBAA 5IKAA 2F8ZF 4NKFA 3N3DA 1KIZA 4QPFA 1VG3A 3OACB 3WCMA 5DJRF 2E94A 4PVYF 4LLSA 2PS5A 4LA6A 4RXCA 5EAUA 3ACYA 4ZQ8A 1WL1A 5HNAA 2Z4XA 1EZFA 5DHIA 3WCHA 5B0KA 5IK0A 1HXAA 4GA3A 3WCCA 3N5HF 5DZ2A 1HM4A 1WY0A 5A0JA 2J1OA 3WEJA 3BNYA 2E93A 2QISA 4KPJA 5JUZF 3AE0A 2E95A 5IMPA 5EATA 4LTVA 5DJPF 1JFAA 4KKMA 3WEIA 2VF6A 5B0IA 3WJOA 1YV5A 2E90A 3WCGA 2AELA 3KRPA 2Z78A 3LOMA 3Q1OA 5DGSF 3DYFA 5C05A 2ZY1A 3SDUA 4LPHF 5IMNA 4H5EF 4KVIA 4NKEA 1VG4A 2OA6A 3OYRA 4NFIF 3ACXA 2OGDA 5AELA 1YYQA 4FJQA 5IVGA 4E9ZA 3APZA 1JFGA 1YYSA 4RXEA 5E8KA 3RMGA 3SDQA 3EGTA 3ICNA 2PS6A 3QKCA 2Z50A 1YYRA 4P0VA 4PVXF 1VG2A 2ONGA 3M0GA 4KQSA 1HXGA 4KQUA 1RTRA 1DI1A 2AZLA 4KWDA 3V1VA 1UBWA 3QQVA 3KRAB 2F9KF 3ICKA 1YQ7A 4OGUA 1ZW5A 3WEHA 4JXYA 3ADZA 4LLTA 3ICZA 3DYGA 3VJ8A 3TS7A 4EA1A 4NG6A 3B7LA 5IKHA 3TFPA 4LFGA 4MC8A 5DJVF 2FORA 2EWGA 3SDTA 5ILJA 2ZEUA 4N9UA 2E8UA 4E1EA 1VG7A 5JV0F 4NUAA 2J5CA 3Q30A 3G4FA 4NFKF 5HN8A 3KBKA 1HXCA 4DWGA 3WCJA 3N1VF 3LMDA 3WJNA 3N1WF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3M00 A;  5B0J A;  3ZL6 A;  3NPK A;  5DHK A;  4QXS F;  2Z4Z A;  3KRC B;  3LG5 A;  4LIX A;  5JV2 F;  3N49 F;  3V66 A;  5IM1 A;  4DEM F;  1V4K A;  2ZCO A;  3WSB A;  3N5J F;  3KRF B;  3NF2 A;  2PS7 A;  1VG6 A;  3KRO A;  2RAH A;  5A0K A;  4XQR F;  1DGP A;  4KVW A;  4JXN A;  3KRA A;  4RYP A;  1WL2 A;  5DGN F;  4WK5 A;  5ERM A;  3WCI A;  2I19 A;  4GP2 A;  5AFX A;  2ZEV A;  4K10 A;  1N20 A;  3VJC A;  1N22 A;  3LVS A;  4OKZ A;  3WC9 A;  3WEF A;  4L2X F;  1PS1 A;  3G4D A;  2E92 A;  1UBY A;  3ASX A;  3RYW A;  3WCA A;  2E8W A;  2H8O A;  4LFE A;  3WCF A;  2F89 F;  2Q58 A;  1WL3 A;  2F8C F;  3KRO B;  3AQB B;  2E8T A;  2OPN A;  4LZC A;  3UCA A;  1N24 A;  1N1B A;  2O1O A;  2J1P A;  1WL0 A;  3Q2Z A;  2F94 F;  5B00 A;  3LDW A;  3NPR A;  4LPG F;  4F6X A;  3KRC A;  4DXJ A;  2AET A;  5ILK A;  5ILH A;  3ZCD A;  1YHK A;  5CG5 A;  3SAE A;  1YHM A;  4LFV F;  3WEK A;  5HN7 A;  2ZCQ A;  3SDR A;  1RQJ A;  4LZ3 A;  2E8V A;  3KRF A;  3P8R A;  4MC0 A;  2P1C A;  3P5P A;  2Q9Y A;  5JA0 F;  4HD1 A;  5HN9 A;  4XQT F;  4GAX A;  1YJ4 A;  5AHU B;  3WCB A;  5ILI A;  3PDE A;  4JZB A;  4LXW A;  3ACW A;  2F92 F;  4P0W A;  5ERN A;  3VJA A;  4RXD A;  4F62 A;  2E8X A;  3PYB A;  3TC1 A;  4XQS F;  1V4H A;  2F7M F;  4KVD A;  3N46 F;  1RQI A;  5B01 A;  2FTZ A;  3P41 A;  2AZK A;  4H5D F;  4LTZ A;  2Z7I A;  3N45 F;  3M9U A;  4LA5 A;  3WE9 A;  4KUX A;  4F6V A;  5ILZ A;  4FP4 A;  5AYP A;  3N3L F;  3TFN A;  3EZ3 A;  3OAB B;  5IL8 A;  4RXA A;  3PH7 A;  1UBV A;  5ILY A;  5ILD A;  3LZ9 A;  3WEG A;  4LUU A;  1YYT A;  4OMH A;  4LZ0 A;  5IK9 A;  5E8L A;  3AQC B;  3AQ0 A;  3N0G A;  4MC3 A;  5E8H A;  3WCL A;  3M01 A;  5IN8 A;  1UBX A;  4KQ5 A;  4UMJ A;  3VJD A;  2DH4 A;  5IL3 A;  1WMW A;  3LGK A;  3LGZ B;  1WKZ A;  3PYA A;  3SDV A;  3V1X A;  3S9V A;  4JZX A;  3PKO A;  3ZOU A;  4DZW A;  4EA0 A;  1V4E A;  2ZCR A;  5IK6 A;  4N1Z F;  3CKE A;  5ER8 A;  2Q80 A;  2Z4W A;  4DI5 A;  3VJ9 A;  5IMI A;  4OMG A;  4E9U A;  5A0I A;  4EA2 A;  3LLW A;  3P5R A;  3DYH A;  2E91 A;  3IPI A;  4JYX A;  4H5C F;  1HM7 A;  5DIQ F;  3P8L A;  3VJE A;  5DW7 A;  3KB9 A;  1N21 A;  3WCE A;  3Q2Q A;  3ICM A;  5JV1 F;  5CG6 A;  4LOB A;  1N1Z A;  3ZMC A;  3ID0 A;  5H9D A;  4DWB A;  4P0X A;  2OPM A;  4JVJ F;  5DGM F;  4Q23 A;  3OAB A;  2Z7H A;  2Z4Y A;  4KK2 A;  3RYE A;  3TFV A;  3MZV A;  3S4J A;  1KIY A;  4GP1 A;  3LJI A;  1FPS A;  3ZMB A;  3EFQ A;  3CP6 A;  3W7F A;  2ONH A;  2PS4 A;  3LK5 A;  3OAC A;  4KFA A;  3WSA A;  3N6K F;  2Z52 A;  5KSX F;  1V4J A;  3KRP B;  1YYU A;  2Z4V A;  1YHL A;  4NFJ F;  3WJK A;  4KPD A;  5ERO A;  2ZCS A;  5I1U A;  3RBM A;  1HX9 A;  3LSN A;  2Q9Z A;  3VJB A;  5B03 A;  4DHD A;  5B0M A;  4KVY A;  3NRI A;  3MAV A;  3WCD A;  1V4I A;  2AEK A;  3LEE A;  5B0L A;  3N0F A;  5B02 A;  5EAS A;  3CC9 A;  4OKM A;  2E4O A;  4RNQ A;  3M02 A;  2AZJ A;  1N23 A;  3BNX A;  2PS8 A;  3IBA A;  5IKA A;  2F8Z F;  4NKF A;  3N3D A;  1KIZ A;  4QPF A;  1VG3 A;  3OAC B;  3WCM A;  5DJR F;  2E94 A;  4PVY F;  4LLS A;  2PS5 A;  4LA6 A;  4RXC A;  5EAU A;  3ACY A;  4ZQ8 A;  1WL1 A;  5HNA A;  2Z4X A;  1EZF A;  5DHI A;  3WCH A;  5B0K A;  5IK0 A;  1HXA A;  4GA3 A;  3WCC A;  3N5H F;  5DZ2 A;  1HM4 A;  1WY0 A;  5A0J A;  2J1O A;  3WEJ A;  3BNY A;  2E93 A;  2QIS A;  4KPJ A;  5JUZ F;  3AE0 A;  2E95 A;  5IMP A;  5EAT A;  4LTV A;  5DJP F;  1JFA A;  4KKM A;  3WEI A;  2VF6 A;  5B0I A;  3WJO A;  1YV5 A;  2E90 A;  3WCG A;  2AEL A;  3KRP A;  2Z78 A;  3LOM A;  3Q1O A;  5DGS F;  3DYF A;  5C05 A;  2ZY1 A;  3SDU A;  4LPH F;  5IMN A;  4H5E F;  4KVI A;  4NKE A;  1VG4 A;  2OA6 A;  3OYR A;  4NFI F;  3ACX A;  2OGD A;  5AEL A;  1YYQ A;  4FJQ A;  5IVG A;  4E9Z A;  3APZ A;  1JFG A;  1YYS A;  4RXE A;  5E8K A;  3RMG A;  3SDQ A;  3EGT A;  3ICN A;  2PS6 A;  3QKC A;  2Z50 A;  1YYR A;  4P0V A;  4PVX F;  1VG2 A;  2ONG A;  3M0G A;  4KQS A;  1HXG A;  4KQU A;  1RTR A;  1DI1 A;  2AZL A;  4KWD A;  3V1V A;  1UBW A;  3QQV A;  3KRA B;  2F9K F;  3ICK A;  1YQ7 A;  4OGU A;  1ZW5 A;  3WEH A;  4JXY A;  3ADZ A;  4LLT A;  3ICZ A;  3DYG A;  3VJ8 A;  3TS7 A;  4EA1 A;  4NG6 A;  3B7L A;  5IKH A;  3TFP A;  4LFG A;  4MC8 A;  5DJV F;  2FOR A;  2EWG A;  3SDT A;  5ILJ A;  2ZEU A;  4N9U A;  2E8U A;  4E1E A;  1VG7 A;  5JV0 F;  4NUA A;  2J5C A;  3Q30 A;  3G4F A;  4NFK F;  5HN8 A;  3KBK A;  1HXC A;  4DWG A;  3WCJ A;  3N1V F;  3LMD A;  3WJN A;  3N1W F; 
#chains in the Genus database with same CATH topology
 3M00 A;  5B0J A;  3ZL6 A;  3NPK A;  5DHK A;  4QXS F;  2Z4Z A;  3KRC B;  3LG5 A;  4LIX A;  5JV2 F;  3N49 F;  3V66 A;  5IM1 A;  4DEM F;  1V4K A;  2ZCO A;  3WSB A;  3N5J F;  3KRF B;  3NF2 A;  2PS7 A;  1VG6 A;  3KRO A;  2RAH A;  5A0K A;  4XQR F;  1DGP A;  4KVW A;  4JXN A;  3KRA A;  4RYP A;  1WL2 A;  5DGN F;  4WK5 A;  5ERM A;  3WCI A;  2I19 A;  4GP2 A;  5AFX A;  2ZEV A;  4K10 A;  1N20 A;  3VJC A;  1N22 A;  3LVS A;  4OKZ A;  3WC9 A;  3WEF A;  4L2X F;  1PS1 A;  3G4D A;  2E92 A;  1UBY A;  3ASX A;  3RYW A;  3WCA A;  2E8W A;  2H8O A;  4LFE A;  3WCF A;  2F89 F;  2Q58 A;  1WL3 A;  2F8C F;  3KRO B;  3AQB B;  2E8T A;  2OPN A;  4LZC A;  3UCA A;  1N24 A;  1N1B A;  2O1O A;  2J1P A;  1WL0 A;  3Q2Z A;  2F94 F;  5B00 A;  3LDW A;  3NPR A;  4LPG F;  4F6X A;  3KRC A;  4DXJ A;  2AET A;  5ILK A;  5ILH A;  3ZCD A;  1YHK A;  5CG5 A;  3SAE A;  1YHM A;  4LFV F;  3WEK A;  5HN7 A;  2ZCQ A;  3SDR A;  1RQJ A;  4LZ3 A;  2E8V A;  3KRF A;  3P8R A;  4MC0 A;  2P1C A;  3P5P A;  2Q9Y A;  5JA0 F;  4HD1 A;  5HN9 A;  4XQT F;  4GAX A;  1YJ4 A;  5AHU B;  3WCB A;  5ILI A;  3PDE A;  4JZB A;  4LXW A;  3ACW A;  2F92 F;  4P0W A;  5ERN A;  3VJA A;  4RXD A;  4F62 A;  2E8X A;  3PYB A;  3TC1 A;  4XQS F;  1V4H A;  2F7M F;  4KVD A;  3N46 F;  1RQI A;  5B01 A;  2FTZ A;  3P41 A;  2AZK A;  4H5D F;  4LTZ A;  2Z7I A;  3N45 F;  3M9U A;  4LA5 A;  3WE9 A;  4KUX A;  4F6V A;  5ILZ A;  4FP4 A;  5AYP A;  3N3L F;  3TFN A;  3EZ3 A;  3OAB B;  5IL8 A;  4RXA A;  3PH7 A;  1UBV A;  5ILY A;  5ILD A;  3LZ9 A;  3WEG A;  4LUU A;  1YYT A;  4OMH A;  4LZ0 A;  5IK9 A;  5E8L A;  3AQC B;  3AQ0 A;  3N0G A;  4MC3 A;  5E8H A;  3WCL A;  3M01 A;  5IN8 A;  1UBX A;  4KQ5 A;  4UMJ A;  3VJD A;  2DH4 A;  5IL3 A;  1WMW A;  3LGK A;  3LGZ B;  1WKZ A;  3PYA A;  3SDV A;  3V1X A;  3S9V A;  4JZX A;  3PKO A;  3ZOU A;  4DZW A;  4EA0 A;  1V4E A;  2ZCR A;  5IK6 A;  4N1Z F;  3CKE A;  5ER8 A;  2Q80 A;  2Z4W A;  4DI5 A;  3VJ9 A;  5IMI A;  4OMG A;  4E9U A;  5A0I A;  4EA2 A;  3LLW A;  3P5R A;  3DYH A;  2E91 A;  3IPI A;  4JYX A;  4H5C F;  1HM7 A;  5DIQ F;  3P8L A;  3VJE A;  5DW7 A;  3KB9 A;  1N21 A;  3WCE A;  3Q2Q A;  3ICM A;  5JV1 F;  5CG6 A;  4LOB A;  1N1Z A;  3ZMC A;  3ID0 A;  5H9D A;  4DWB A;  4P0X A;  2OPM A;  4JVJ F;  5DGM F;  4Q23 A;  3OAB A;  2Z7H A;  2Z4Y A;  4KK2 A;  3RYE A;  3TFV A;  3MZV A;  3S4J A;  1KIY A;  4GP1 A;  3LJI A;  1FPS A;  3ZMB A;  3EFQ A;  3CP6 A;  3W7F A;  2ONH A;  2PS4 A;  3LK5 A;  3OAC A;  4KFA A;  3WSA A;  3N6K F;  2Z52 A;  5KSX F;  1V4J A;  3KRP B;  1YYU A;  2Z4V A;  1YHL A;  4NFJ F;  3WJK A;  4KPD A;  5ERO A;  2ZCS A;  5I1U A;  3RBM A;  1HX9 A;  3LSN A;  2Q9Z A;  3VJB A;  5B03 A;  4DHD A;  5B0M A;  4KVY A;  3NRI A;  3MAV A;  3WCD A;  1V4I A;  2AEK A;  3LEE A;  5B0L A;  3N0F A;  5B02 A;  5EAS A;  3CC9 A;  4OKM A;  2E4O A;  4RNQ A;  3M02 A;  2AZJ A;  1N23 A;  3BNX A;  2PS8 A;  3IBA A;  5IKA A;  2F8Z F;  4NKF A;  3N3D A;  1KIZ A;  4QPF A;  1VG3 A;  3OAC B;  3WCM A;  5DJR F;  2E94 A;  4PVY F;  4LLS A;  2PS5 A;  4LA6 A;  4RXC A;  5EAU A;  3ACY A;  4ZQ8 A;  1WL1 A;  5HNA A;  2Z4X A;  1EZF A;  5DHI A;  3WCH A;  5B0K A;  5IK0 A;  1HXA A;  4GA3 A;  3WCC A;  3N5H F;  5DZ2 A;  1HM4 A;  1WY0 A;  5A0J A;  2J1O A;  3WEJ A;  3BNY A;  2E93 A;  2QIS A;  4KPJ A;  5JUZ F;  3AE0 A;  2E95 A;  5IMP A;  5EAT A;  4LTV A;  5DJP F;  1JFA A;  4KKM A;  3WEI A;  2VF6 A;  5B0I A;  3WJO A;  1YV5 A;  2E90 A;  3WCG A;  2AEL A;  3KRP A;  2Z78 A;  3LOM A;  3Q1O A;  5DGS F;  3DYF A;  5C05 A;  2ZY1 A;  3SDU A;  4LPH F;  5IMN A;  4H5E F;  4KVI A;  4NKE A;  1VG4 A;  2OA6 A;  3OYR A;  4NFI F;  3ACX A;  2OGD A;  5AEL A;  1YYQ A;  4FJQ A;  5IVG A;  4E9Z A;  3APZ A;  1JFG A;  1YYS A;  4RXE A;  5E8K A;  3RMG A;  3SDQ A;  3EGT A;  3ICN A;  2PS6 A;  3QKC A;  2Z50 A;  1YYR A;  4P0V A;  4PVX F;  1VG2 A;  2ONG A;  3M0G A;  4KQS A;  1HXG A;  4KQU A;  1RTR A;  1DI1 A;  2AZL A;  4KWD A;  3V1V A;  1UBW A;  3QQV A;  3KRA B;  2F9K F;  3ICK A;  1YQ7 A;  4OGU A;  1ZW5 A;  3WEH A;  4JXY A;  3ADZ A;  4LLT A;  3ICZ A;  3DYG A;  3VJ8 A;  3TS7 A;  4EA1 A;  4NG6 A;  3B7L A;  5IKH A;  3TFP A;  4LFG A;  4MC8 A;  5DJV F;  2FOR A;  2EWG A;  3SDT A;  5ILJ A;  2ZEU A;  4N9U A;  2E8U A;  4E1E A;  1VG7 A;  5JV0 F;  4NUA A;  2J5C A;  3Q30 A;  3G4F A;  4NFK F;  5HN8 A;  3KBK A;  1HXC A;  4DWG A;  3WCJ A;  3N1V F;  3LMD A;  3WJN A;  3N1W F; 
#chains in the Genus database with same CATH homology
 3M00 A;  5B0J A;  3ZL6 A;  3NPK A;  5DHK A;  4QXS F;  2Z4Z A;  3KRC B;  3LG5 A;  4LIX A;  5JV2 F;  3N49 F;  3V66 A;  5IM1 A;  4DEM F;  1V4K A;  2ZCO A;  3WSB A;  3N5J F;  3KRF B;  3NF2 A;  2PS7 A;  1VG6 A;  3KRO A;  2RAH A;  5A0K A;  4XQR F;  1DGP A;  4KVW A;  4JXN A;  3KRA A;  4RYP A;  1WL2 A;  5DGN F;  4WK5 A;  5ERM A;  3WCI A;  2I19 A;  4GP2 A;  5AFX A;  2ZEV A;  4K10 A;  1N20 A;  3VJC A;  1N22 A;  3LVS A;  4OKZ A;  3WC9 A;  3WEF A;  4L2X F;  1PS1 A;  3G4D A;  2E92 A;  1UBY A;  3ASX A;  3RYW A;  3WCA A;  2E8W A;  2H8O A;  4LFE A;  3WCF A;  2F89 F;  2Q58 A;  1WL3 A;  2F8C F;  3KRO B;  3AQB B;  2E8T A;  2OPN A;  4LZC A;  3UCA A;  1N24 A;  1N1B A;  2O1O A;  2J1P A;  1WL0 A;  3Q2Z A;  2F94 F;  5B00 A;  3LDW A;  3NPR A;  4LPG F;  4F6X A;  3KRC A;  4DXJ A;  2AET A;  5ILK A;  5ILH A;  3ZCD A;  1YHK A;  5CG5 A;  3SAE A;  1YHM A;  4LFV F;  3WEK A;  5HN7 A;  2ZCQ A;  3SDR A;  1RQJ A;  4LZ3 A;  2E8V A;  3KRF A;  3P8R A;  4MC0 A;  2P1C A;  3P5P A;  2Q9Y A;  5JA0 F;  4HD1 A;  5HN9 A;  4XQT F;  4GAX A;  1YJ4 A;  5AHU B;  3WCB A;  5ILI A;  3PDE A;  4JZB A;  4LXW A;  3ACW A;  2F92 F;  4P0W A;  5ERN A;  3VJA A;  4RXD A;  4F62 A;  2E8X A;  3PYB A;  3TC1 A;  4XQS F;  1V4H A;  2F7M F;  4KVD A;  3N46 F;  1RQI A;  5B01 A;  2FTZ A;  3P41 A;  2AZK A;  4H5D F;  4LTZ A;  2Z7I A;  3N45 F;  3M9U A;  4LA5 A;  3WE9 A;  4KUX A;  4F6V A;  5ILZ A;  4FP4 A;  5AYP A;  3N3L F;  3TFN A;  3EZ3 A;  3OAB B;  5IL8 A;  4RXA A;  3PH7 A;  1UBV A;  5ILY A;  5ILD A;  3LZ9 A;  3WEG A;  4LUU A;  1YYT A;  4OMH A;  4LZ0 A;  5IK9 A;  5E8L A;  3AQC B;  3AQ0 A;  3N0G A;  4MC3 A;  5E8H A;  3WCL A;  3M01 A;  5IN8 A;  1UBX A;  4KQ5 A;  4UMJ A;  3VJD A;  2DH4 A;  5IL3 A;  1WMW A;  3LGK A;  3LGZ B;  1WKZ A;  3PYA A;  3SDV A;  3V1X A;  3S9V A;  4JZX A;  3PKO A;  3ZOU A;  4DZW A;  4EA0 A;  1V4E A;  2ZCR A;  5IK6 A;  4N1Z F;  3CKE A;  5ER8 A;  2Q80 A;  2Z4W A;  4DI5 A;  3VJ9 A;  5IMI A;  4OMG A;  4E9U A;  5A0I A;  4EA2 A;  3LLW A;  3P5R A;  3DYH A;  2E91 A;  3IPI A;  4JYX A;  4H5C F;  1HM7 A;  5DIQ F;  3P8L A;  3VJE A;  5DW7 A;  3KB9 A;  1N21 A;  3WCE A;  3Q2Q A;  3ICM A;  5JV1 F;  5CG6 A;  4LOB A;  1N1Z A;  3ZMC A;  3ID0 A;  5H9D A;  4DWB A;  4P0X A;  2OPM A;  4JVJ F;  5DGM F;  4Q23 A;  3OAB A;  2Z7H A;  2Z4Y A;  4KK2 A;  3RYE A;  3TFV A;  3MZV A;  3S4J A;  1KIY A;  4GP1 A;  3LJI A;  1FPS A;  3ZMB A;  3EFQ A;  3CP6 A;  3W7F A;  2ONH A;  2PS4 A;  3LK5 A;  3OAC A;  4KFA A;  3WSA A;  3N6K F;  2Z52 A;  5KSX F;  1V4J A;  3KRP B;  1YYU A;  2Z4V A;  1YHL A;  4NFJ F;  3WJK A;  4KPD A;  5ERO A;  2ZCS A;  5I1U A;  3RBM A;  1HX9 A;  3LSN A;  2Q9Z A;  3VJB A;  5B03 A;  4DHD A;  5B0M A;  4KVY A;  3NRI A;  3MAV A;  3WCD A;  1V4I A;  2AEK A;  3LEE A;  5B0L A;  3N0F A;  5B02 A;  5EAS A;  3CC9 A;  4OKM A;  2E4O A;  4RNQ A;  3M02 A;  2AZJ A;  1N23 A;  3BNX A;  2PS8 A;  3IBA A;  5IKA A;  2F8Z F;  4NKF A;  3N3D A;  1KIZ A;  4QPF A;  1VG3 A;  3OAC B;  3WCM A;  5DJR F;  2E94 A;  4PVY F;  4LLS A;  2PS5 A;  4LA6 A;  4RXC A;  5EAU A;  3ACY A;  4ZQ8 A;  1WL1 A;  5HNA A;  2Z4X A;  1EZF A;  5DHI A;  3WCH A;  5B0K A;  5IK0 A;  1HXA A;  4GA3 A;  3WCC A;  3N5H F;  5DZ2 A;  1HM4 A;  1WY0 A;  5A0J A;  2J1O A;  3WEJ A;  3BNY A;  2E93 A;  2QIS A;  4KPJ A;  5JUZ F;  3AE0 A;  2E95 A;  5IMP A;  5EAT A;  4LTV A;  5DJP F;  1JFA A;  4KKM A;  3WEI A;  2VF6 A;  5B0I A;  3WJO A;  1YV5 A;  2E90 A;  3WCG A;  2AEL A;  3KRP A;  2Z78 A;  3LOM A;  3Q1O A;  5DGS F;  3DYF A;  5C05 A;  2ZY1 A;  3SDU A;  4LPH F;  5IMN A;  4H5E F;  4KVI A;  4NKE A;  1VG4 A;  2OA6 A;  3OYR A;  4NFI F;  3ACX A;  2OGD A;  5AEL A;  1YYQ A;  4FJQ A;  5IVG A;  4E9Z A;  3APZ A;  1JFG A;  1YYS A;  4RXE A;  5E8K A;  3RMG A;  3SDQ A;  3EGT A;  3ICN A;  2PS6 A;  3QKC A;  2Z50 A;  1YYR A;  4P0V A;  4PVX F;  1VG2 A;  2ONG A;  3M0G A;  4KQS A;  1HXG A;  4KQU A;  1RTR A;  1DI1 A;  2AZL A;  4KWD A;  3V1V A;  1UBW A;  3QQV A;  3KRA B;  2F9K F;  3ICK A;  1YQ7 A;  4OGU A;  1ZW5 A;  3WEH A;  4JXY A;  3ADZ A;  4LLT A;  3ICZ A;  3DYG A;  3VJ8 A;  3TS7 A;  4EA1 A;  4NG6 A;  3B7L A;  5IKH A;  3TFP A;  4LFG A;  4MC8 A;  5DJV F;  2FOR A;  2EWG A;  3SDT A;  5ILJ A;  2ZEU A;  4N9U A;  2E8U A;  4E1E A;  1VG7 A;  5JV0 F;  4NUA A;  2J5C A;  3Q30 A;  3G4F A;  4NFK F;  5HN8 A;  3KBK A;  1HXC A;  4DWG A;  3WCJ A;  3N1V F;  3LMD A;  3WJN A;  3N1W F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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