2F7MF

Crystal structure of unliganded human fpps
Total Genus 130
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
130
sequence length
341
structure length
341
Chain Sequence
VYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Farnesyl Diphosphate Synthase
publication title Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 130
structure length 341
sequence length 341
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2005-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 2f7mF00
5B00A 1VG6A 2ZCOA 3DYGA 3V1XA 3CP6A 5JV2F 3WCLA 3KRPA 5C05A 4MC3A 3PKOA 4EA0A 1RQIA 4KVYA 5IKHA 5EATA 4DEMF 5A0IA 5DIQF 5HN8A 1KIYA 5IMPA 3WSAA 2E93A 3NPKA 4RXDA 2PS8A 1VG2A 4H5EF 1HX9A 3WCJA 5A0JA 1WL3A 4LIXA 4OKZA 3N3LF 3KRAB 3WCHA 2J1PA 3DYHA 1V4EA 4DWGA 3KRFB 5ER8A 2PS4A 4XQSF 4N9UA 2H8OA 5ILIA 3S4JA 2J1OA 2ZEUA 5B02A 3SAEA 3ACXA 3BNYA 3VJAA 3QKCA 5DJVF 4JVJF 2AETA 3OACB 5A0KA 4PVYF 4OMGA 4DI5A 2VF6A 4MC8A 3RYWA 2ZCRA 3ZMCA 4RXEA 2ONHA 2AZJA 1N21A 4LFVF 2PS6A 4NKFA 5EROA 2E94A 3WSBA 4NUAA 1YJ4A 1ZW5A 4K10A 3N49F 3V66A 2AEKA 1WL2A 5AFXA 4L2XF 3PDEA 3WCGA 3TFNA 3SDTA 3MAVA 5B0MA 5E8HA 3KROA 4E1EA 3NF2A 3M00A 1YV5A 5IMIA 3M02A 2Z4XA 3MZVA 5IN8A 1YHLA 5DZ2A 3LOMA 3LK5A 3N1WF 3P8RA 4LLSA 3OABA 4LA6A 3P5PA 5IK6A 5DGSF 2AZKA 4F6VA 5B03A 4LPHF 3LEEA 1DGPA 5DHIA 3Q2QA 3PYAA 2Q9YA 5JV1F 3G4FA 5E8LA 3SDVA 5ILKA 3M0GA 2QISA 5B0LA 3CC9A 3WCAA 3N0FA 1WL1A 3KRPB 5I1UA 3G4DA 3LZ9A 1HM7A 1WMWA 4JXNA 3ICNA 4PVXF 4DWBA 1JFGA 2Q9ZA 3WCMA 3ICKA 3ZL6A 1WL0A 3AQ0A 4RNQA 2E8XA 2F8CF 3TFVA 2OGDA 5CG6A 1V4JA 2E4OA 3WJNA 3N1VF 4LFEA 4LFGA 2PS5A 2P1CA 2Q80A 2ZCQA 5ERNA 3KB9A 3SDRA 4FP4A 4XQTF 3QQVA 4NFIF 3VJDA 4NFJF 4KVIA 4QXSF 5AHUB 3B7LA 1HXCA 2E8UA 1YYTA 2E91A 4RXAA 1YYSA 2F92F 5JUZF 3OYRA 3WCFA 2RAHA 3EGTA 3LGKA 3LVSA 3N45F 3IBAA 1VG3A 3VJEA 3WEHA 1HM4A 3WEKA 2Z78A 2Z4ZA 2ZY1A 3N5JF 1V4HA 3ZMBA 3Q1OA 4JYXA 5ILDA 3WJKA 1JFAA 1V4IA 1YQ7A 4UMJA 2Z7HA 5B0KA 5ILJA 3ID0A 3WEJA 5IVGA 3TFPA 2J5CA 5B0IA 5IM1A 5KSXF 1N22A 4P0XA 3TS7A 1RTRA 3KROB 4P0WA 5HNAA 2F94F 3LDWA 5IK9A 4NG6A 4HD1A 4KQUA 3AQCB 1VG7A 3WCDA 4OGUA 4E9UA 4LUUA 4GP1A 3ICZA 1PS1A 3VJCA 3LLWA 4LOBA 1DI1A 4LZ0A 4LTVA 4GAXA 3OABB 5DHKA 3NPRA 5IMNA 4KQSA 3CKEA 2E95A 3WCCA 3Q30A 4LXWA 3RMGA 3WCIA 5CG5A 1YYRA 2O1OA 1N20A 3N3DA 4LLTA 1WY0A 3WEIA 4MC0A 2ZCSA 4GP2A 3N0GA 3EFQA 2Z7IA 3VJBA 3KRCA 4F62A 2E8TA 2Z4VA 4KKMA 3N6KF 4P0VA 1N23A 4Q23A 1UBVA 2I19A 2F7MF 4KUXA 5IK0A 4FJQA 4KPJA 4NKEA 4LTZA 4KQ5A 3M01A 5B01A 4XQRF 3LG5A 4JXYA 2F89F 2AZLA 3Q2ZA 4NFKF 3WCEA 3SDUA 3WCBA 3M9UA 3ACYA 4N1ZF 3TC1A 2Q58A 2ONGA 5IL8A 3RYEA 2E8VA 3AQBB 4QPFA 5EASA 4LZ3A 3ZOUA 3P8LA 5B0JA 3W7FA 3VJ8A 2Z50A 5DJRF 1VG4A 4E9ZA 2Z4WA 1N24A 5E8KA 5IKAA 1EZFA 4LPGF 3N46F 5IL3A 5HN7A 3EZ3A 4F6XA 1YHKA 3V1VA 3WJOA 2E8WA 3WEFA 3AE0A 3LSNA 1N1BA 5DJPF 3ZCDA 3N5HF 3KRAA 4ZQ8A 3LMDA 3PH7A 2PS7A 1N1ZA 4H5DF 3KRFA 5DGNF 5ILYA 1YYQA 5DW7A 5ERMA 3NRIA 4H5CF 3LGZB 5EAUA 1UBWA 5ILZA 3KBKA 5ILHA 2DH4A 2EWGA 2Z4YA 5DGMF 3BNXA 3VJ9A 3OACA 2ZEVA 4JZXA 1YHMA 2F9KF 4WK5A 4KK2A 4EA2A 2FORA 5JV0F 4LZCA 4DXJA 1FPSA 3ACWA 3P5RA 2FTZA 3PYBA 3KRCB 3WC9A 1KIZA 3UCAA 4RYPA 3RBMA 4KFAA 1YYUA 4LA5A 1UBXA 3LJIA 3ADZA 4RXCA 1UBYA 1RQJA 4KVDA 3ASXA 5JA0F 4DHDA 4KPDA 5H9DA 2OPMA 3WE9A 4GA3A 3S9VA 4DZWA 3WEGA 2F8ZF 1WKZA 5HN9A 2OA6A 4JZBA 4OMHA 2Z52A 4EA1A 3IPIA 2E90A 5AYPA 1HXAA 5AELA 2AELA 1HXGA 2OPNA 3APZA 4KVWA 4OKMA 3SDQA 1V4KA 3DYFA 2E92A 3ICMA 3P41A 4KWDA
chains in the Genus database with same CATH superfamily
5B00A 1VG6A 2ZCOA 3DYGA 3V1XA 3CP6A 5JV2F 3WCLA 3KRPA 5C05A 4MC3A 3PKOA 4EA0A 1RQIA 4KVYA 5IKHA 5EATA 4DEMF 5A0IA 5DIQF 5HN8A 1KIYA 5IMPA 3WSAA 2E93A 3NPKA 4RXDA 2PS8A 1VG2A 4H5EF 1HX9A 3WCJA 5A0JA 1WL3A 4LIXA 4OKZA 3N3LF 3KRAB 3WCHA 2J1PA 3DYHA 1V4EA 4DWGA 3KRFB 5ER8A 2PS4A 4XQSF 4N9UA 2H8OA 5ILIA 3S4JA 2J1OA 2ZEUA 5B02A 3SAEA 3ACXA 3BNYA 3VJAA 3QKCA 5DJVF 4JVJF 2AETA 3OACB 5A0KA 4PVYF 4OMGA 4DI5A 2VF6A 4MC8A 3RYWA 2ZCRA 3ZMCA 4RXEA 2ONHA 2AZJA 1N21A 4LFVF 2PS6A 4NKFA 5EROA 2E94A 3WSBA 4NUAA 1YJ4A 1ZW5A 4K10A 3N49F 3V66A 2AEKA 1WL2A 5AFXA 4L2XF 3PDEA 3WCGA 3TFNA 3SDTA 3MAVA 5B0MA 5E8HA 3KROA 4E1EA 3NF2A 3M00A 1YV5A 5IMIA 3M02A 2Z4XA 3MZVA 5IN8A 1YHLA 5DZ2A 3LOMA 3LK5A 3N1WF 3P8RA 4LLSA 3OABA 4LA6A 3P5PA 5IK6A 5DGSF 2AZKA 4F6VA 5B03A 4LPHF 3LEEA 1DGPA 5DHIA 3Q2QA 3PYAA 2Q9YA 5JV1F 3G4FA 5E8LA 3SDVA 5ILKA 3M0GA 2QISA 5B0LA 3CC9A 3WCAA 3N0FA 1WL1A 3KRPB 5I1UA 3G4DA 3LZ9A 1HM7A 1WMWA 4JXNA 3ICNA 4PVXF 4DWBA 1JFGA 2Q9ZA 3WCMA 3ICKA 3ZL6A 1WL0A 3AQ0A 4RNQA 2E8XA 2F8CF 3TFVA 2OGDA 5CG6A 1V4JA 2E4OA 3WJNA 3N1VF 4LFEA 4LFGA 2PS5A 2P1CA 2Q80A 2ZCQA 5ERNA 3KB9A 3SDRA 4FP4A 4XQTF 3QQVA 4NFIF 3VJDA 4NFJF 4KVIA 4QXSF 5AHUB 3B7LA 1HXCA 2E8UA 1YYTA 2E91A 4RXAA 1YYSA 2F92F 5JUZF 3OYRA 3WCFA 2RAHA 3EGTA 3LGKA 3LVSA 3N45F 3IBAA 1VG3A 3VJEA 3WEHA 1HM4A 3WEKA 2Z78A 2Z4ZA 2ZY1A 3N5JF 1V4HA 3ZMBA 3Q1OA 4JYXA 5ILDA 3WJKA 1JFAA 1V4IA 1YQ7A 4UMJA 2Z7HA 5B0KA 5ILJA 3ID0A 3WEJA 5IVGA 3TFPA 2J5CA 5B0IA 5IM1A 5KSXF 1N22A 4P0XA 3TS7A 1RTRA 3KROB 4P0WA 5HNAA 2F94F 3LDWA 5IK9A 4NG6A 4HD1A 4KQUA 3AQCB 1VG7A 3WCDA 4OGUA 4E9UA 4LUUA 4GP1A 3ICZA 1PS1A 3VJCA 3LLWA 4LOBA 1DI1A 4LZ0A 4LTVA 4GAXA 3OABB 5DHKA 3NPRA 5IMNA 4KQSA 3CKEA 2E95A 3WCCA 3Q30A 4LXWA 3RMGA 3WCIA 5CG5A 1YYRA 2O1OA 1N20A 3N3DA 4LLTA 1WY0A 3WEIA 4MC0A 2ZCSA 4GP2A 3N0GA 3EFQA 2Z7IA 3VJBA 3KRCA 4F62A 2E8TA 2Z4VA 4KKMA 3N6KF 4P0VA 1N23A 4Q23A 1UBVA 2I19A 2F7MF 4KUXA 5IK0A 4FJQA 4KPJA 4NKEA 4LTZA 4KQ5A 3M01A 5B01A 4XQRF 3LG5A 4JXYA 2F89F 2AZLA 3Q2ZA 4NFKF 3WCEA 3SDUA 3WCBA 3M9UA 3ACYA 4N1ZF 3TC1A 2Q58A 2ONGA 5IL8A 3RYEA 2E8VA 3AQBB 4QPFA 5EASA 4LZ3A 3ZOUA 3P8LA 5B0JA 3W7FA 3VJ8A 2Z50A 5DJRF 1VG4A 4E9ZA 2Z4WA 1N24A 5E8KA 5IKAA 1EZFA 4LPGF 3N46F 5IL3A 5HN7A 3EZ3A 4F6XA 1YHKA 3V1VA 3WJOA 2E8WA 3WEFA 3AE0A 3LSNA 1N1BA 5DJPF 3ZCDA 3N5HF 3KRAA 4ZQ8A 3LMDA 3PH7A 2PS7A 1N1ZA 4H5DF 3KRFA 5DGNF 5ILYA 1YYQA 5DW7A 5ERMA 3NRIA 4H5CF 3LGZB 5EAUA 1UBWA 5ILZA 3KBKA 5ILHA 2DH4A 2EWGA 2Z4YA 5DGMF 3BNXA 3VJ9A 3OACA 2ZEVA 4JZXA 1YHMA 2F9KF 4WK5A 4KK2A 4EA2A 2FORA 5JV0F 4LZCA 4DXJA 1FPSA 3ACWA 3P5RA 2FTZA 3PYBA 3KRCB 3WC9A 1KIZA 3UCAA 4RYPA 3RBMA 4KFAA 1YYUA 4LA5A 1UBXA 3LJIA 3ADZA 4RXCA 1UBYA 1RQJA 4KVDA 3ASXA 5JA0F 4DHDA 4KPDA 5H9DA 2OPMA 3WE9A 4GA3A 3S9VA 4DZWA 3WEGA 2F8ZF 1WKZA 5HN9A 2OA6A 4JZBA 4OMHA 2Z52A 4EA1A 3IPIA 2E90A 5AYPA 1HXAA 5AELA 2AELA 1HXGA 2OPNA 3APZA 4KVWA 4OKMA 3SDQA 1V4KA 3DYFA 2E92A 3ICMA 3P41A 4KWDA
chains in the Genus database with same CATH topology
5B00A 1VG6A 2ZCOA 3DYGA 3V1XA 3CP6A 5JV2F 3WCLA 3KRPA 5C05A 4MC3A 3PKOA 4EA0A 1RQIA 4KVYA 5IKHA 5EATA 4DEMF 5A0IA 5DIQF 5HN8A 1KIYA 5IMPA 3WSAA 2E93A 3NPKA 4RXDA 2PS8A 1VG2A 4H5EF 1HX9A 3WCJA 5A0JA 1WL3A 4LIXA 4OKZA 3N3LF 3KRAB 3WCHA 2J1PA 3DYHA 1V4EA 4DWGA 3KRFB 5ER8A 2PS4A 4XQSF 4N9UA 2H8OA 5ILIA 3S4JA 2J1OA 2ZEUA 5B02A 3SAEA 3ACXA 3BNYA 3VJAA 3QKCA 5DJVF 4JVJF 2AETA 3OACB 5A0KA 4PVYF 4OMGA 4DI5A 2VF6A 4MC8A 3RYWA 2ZCRA 3ZMCA 4RXEA 2ONHA 2AZJA 1N21A 4LFVF 2PS6A 4NKFA 5EROA 2E94A 3WSBA 4NUAA 1YJ4A 1ZW5A 4K10A 3N49F 3V66A 2AEKA 1WL2A 5AFXA 4L2XF 3PDEA 3WCGA 3TFNA 3SDTA 3MAVA 5B0MA 5E8HA 3KROA 4E1EA 3NF2A 3M00A 1YV5A 5IMIA 3M02A 2Z4XA 3MZVA 5IN8A 1YHLA 5DZ2A 3LOMA 3LK5A 3N1WF 3P8RA 4LLSA 3OABA 4LA6A 3P5PA 5IK6A 5DGSF 2AZKA 4F6VA 5B03A 4LPHF 3LEEA 1DGPA 5DHIA 3Q2QA 3PYAA 2Q9YA 5JV1F 3G4FA 5E8LA 3SDVA 5ILKA 3M0GA 2QISA 5B0LA 3CC9A 3WCAA 3N0FA 1WL1A 3KRPB 5I1UA 3G4DA 3LZ9A 1HM7A 1WMWA 4JXNA 3ICNA 4PVXF 4DWBA 1JFGA 2Q9ZA 3WCMA 3ICKA 3ZL6A 1WL0A 3AQ0A 4RNQA 2E8XA 2F8CF 3TFVA 2OGDA 5CG6A 1V4JA 2E4OA 3WJNA 3N1VF 4LFEA 4LFGA 2PS5A 2P1CA 2Q80A 2ZCQA 5ERNA 3KB9A 3SDRA 4FP4A 4XQTF 3QQVA 4NFIF 3VJDA 4NFJF 4KVIA 4QXSF 5AHUB 3B7LA 1HXCA 2E8UA 1YYTA 2E91A 4RXAA 1YYSA 2F92F 5JUZF 3OYRA 3WCFA 2RAHA 3EGTA 3LGKA 3LVSA 3N45F 3IBAA 1VG3A 3VJEA 3WEHA 1HM4A 3WEKA 2Z78A 2Z4ZA 2ZY1A 3N5JF 1V4HA 3ZMBA 3Q1OA 4JYXA 5ILDA 3WJKA 1JFAA 1V4IA 1YQ7A 4UMJA 2Z7HA 5B0KA 5ILJA 3ID0A 3WEJA 5IVGA 3TFPA 2J5CA 5B0IA 5IM1A 5KSXF 1N22A 4P0XA 3TS7A 1RTRA 3KROB 4P0WA 5HNAA 2F94F 3LDWA 5IK9A 4NG6A 4HD1A 4KQUA 3AQCB 1VG7A 3WCDA 4OGUA 4E9UA 4LUUA 4GP1A 3ICZA 1PS1A 3VJCA 3LLWA 4LOBA 1DI1A 4LZ0A 4LTVA 4GAXA 3OABB 5DHKA 3NPRA 5IMNA 4KQSA 3CKEA 2E95A 3WCCA 3Q30A 4LXWA 3RMGA 3WCIA 5CG5A 1YYRA 2O1OA 1N20A 3N3DA 4LLTA 1WY0A 3WEIA 4MC0A 2ZCSA 4GP2A 3N0GA 3EFQA 2Z7IA 3VJBA 3KRCA 4F62A 2E8TA 2Z4VA 4KKMA 3N6KF 4P0VA 1N23A 4Q23A 1UBVA 2I19A 2F7MF 4KUXA 5IK0A 4FJQA 4KPJA 4NKEA 4LTZA 4KQ5A 3M01A 5B01A 4XQRF 3LG5A 4JXYA 2F89F 2AZLA 3Q2ZA 4NFKF 3WCEA 3SDUA 3WCBA 3M9UA 3ACYA 4N1ZF 3TC1A 2Q58A 2ONGA 5IL8A 3RYEA 2E8VA 3AQBB 4QPFA 5EASA 4LZ3A 3ZOUA 3P8LA 5B0JA 3W7FA 3VJ8A 2Z50A 5DJRF 1VG4A 4E9ZA 2Z4WA 1N24A 5E8KA 5IKAA 1EZFA 4LPGF 3N46F 5IL3A 5HN7A 3EZ3A 4F6XA 1YHKA 3V1VA 3WJOA 2E8WA 3WEFA 3AE0A 3LSNA 1N1BA 5DJPF 3ZCDA 3N5HF 3KRAA 4ZQ8A 3LMDA 3PH7A 2PS7A 1N1ZA 4H5DF 3KRFA 5DGNF 5ILYA 1YYQA 5DW7A 5ERMA 3NRIA 4H5CF 3LGZB 5EAUA 1UBWA 5ILZA 3KBKA 5ILHA 2DH4A 2EWGA 2Z4YA 5DGMF 3BNXA 3VJ9A 3OACA 2ZEVA 4JZXA 1YHMA 2F9KF 4WK5A 4KK2A 4EA2A 2FORA 5JV0F 4LZCA 4DXJA 1FPSA 3ACWA 3P5RA 2FTZA 3PYBA 3KRCB 3WC9A 1KIZA 3UCAA 4RYPA 3RBMA 4KFAA 1YYUA 4LA5A 1UBXA 3LJIA 3ADZA 4RXCA 1UBYA 1RQJA 4KVDA 3ASXA 5JA0F 4DHDA 4KPDA 5H9DA 2OPMA 3WE9A 4GA3A 3S9VA 4DZWA 3WEGA 2F8ZF 1WKZA 5HN9A 2OA6A 4JZBA 4OMHA 2Z52A 4EA1A 3IPIA 2E90A 5AYPA 1HXAA 5AELA 2AELA 1HXGA 2OPNA 3APZA 4KVWA 4OKMA 3SDQA 1V4KA 3DYFA 2E92A 3ICMA 3P41A 4KWDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5B00 A;  1VG6 A;  2ZCO A;  3DYG A;  3V1X A;  3CP6 A;  5JV2 F;  3WCL A;  3KRP A;  5C05 A;  4MC3 A;  3PKO A;  4EA0 A;  1RQI A;  4KVY A;  5IKH A;  5EAT A;  4DEM F;  5A0I A;  5DIQ F;  5HN8 A;  1KIY A;  5IMP A;  3WSA A;  2E93 A;  3NPK A;  4RXD A;  2PS8 A;  1VG2 A;  4H5E F;  1HX9 A;  3WCJ A;  5A0J A;  1WL3 A;  4LIX A;  4OKZ A;  3N3L F;  3KRA B;  3WCH A;  2J1P A;  3DYH A;  1V4E A;  4DWG A;  3KRF B;  5ER8 A;  2PS4 A;  4XQS F;  4N9U A;  2H8O A;  5ILI A;  3S4J A;  2J1O A;  2ZEU A;  5B02 A;  3SAE A;  3ACX A;  3BNY A;  3VJA A;  3QKC A;  5DJV F;  4JVJ F;  2AET A;  3OAC B;  5A0K A;  4PVY F;  4OMG A;  4DI5 A;  2VF6 A;  4MC8 A;  3RYW A;  2ZCR A;  3ZMC A;  4RXE A;  2ONH A;  2AZJ A;  1N21 A;  4LFV F;  2PS6 A;  4NKF A;  5ERO A;  2E94 A;  3WSB A;  4NUA A;  1YJ4 A;  1ZW5 A;  4K10 A;  3N49 F;  3V66 A;  2AEK A;  1WL2 A;  5AFX A;  4L2X F;  3PDE A;  3WCG A;  3TFN A;  3SDT A;  3MAV A;  5B0M A;  5E8H A;  3KRO A;  4E1E A;  3NF2 A;  3M00 A;  1YV5 A;  5IMI A;  3M02 A;  2Z4X A;  3MZV A;  5IN8 A;  1YHL A;  5DZ2 A;  3LOM A;  3LK5 A;  3N1W F;  3P8R A;  4LLS A;  3OAB A;  4LA6 A;  3P5P A;  5IK6 A;  5DGS F;  2AZK A;  4F6V A;  5B03 A;  4LPH F;  3LEE A;  1DGP A;  5DHI A;  3Q2Q A;  3PYA A;  2Q9Y A;  5JV1 F;  3G4F A;  5E8L A;  3SDV A;  5ILK A;  3M0G A;  2QIS A;  5B0L A;  3CC9 A;  3WCA A;  3N0F A;  1WL1 A;  3KRP B;  5I1U A;  3G4D A;  3LZ9 A;  1HM7 A;  1WMW A;  4JXN A;  3ICN A;  4PVX F;  4DWB A;  1JFG A;  2Q9Z A;  3WCM A;  3ICK A;  3ZL6 A;  1WL0 A;  3AQ0 A;  4RNQ A;  2E8X A;  2F8C F;  3TFV A;  2OGD A;  5CG6 A;  1V4J A;  2E4O A;  3WJN A;  3N1V F;  4LFE A;  4LFG A;  2PS5 A;  2P1C A;  2Q80 A;  2ZCQ A;  5ERN A;  3KB9 A;  3SDR A;  4FP4 A;  4XQT F;  3QQV A;  4NFI F;  3VJD A;  4NFJ F;  4KVI A;  4QXS F;  5AHU B;  3B7L A;  1HXC A;  2E8U A;  1YYT A;  2E91 A;  4RXA A;  1YYS A;  2F92 F;  5JUZ F;  3OYR A;  3WCF A;  2RAH A;  3EGT A;  3LGK A;  3LVS A;  3N45 F;  3IBA A;  1VG3 A;  3VJE A;  3WEH A;  1HM4 A;  3WEK A;  2Z78 A;  2Z4Z A;  2ZY1 A;  3N5J F;  1V4H A;  3ZMB A;  3Q1O A;  4JYX A;  5ILD A;  3WJK A;  1JFA A;  1V4I A;  1YQ7 A;  4UMJ A;  2Z7H A;  5B0K A;  5ILJ A;  3ID0 A;  3WEJ A;  5IVG A;  3TFP A;  2J5C A;  5B0I A;  5IM1 A;  5KSX F;  1N22 A;  4P0X A;  3TS7 A;  1RTR A;  3KRO B;  4P0W A;  5HNA A;  2F94 F;  3LDW A;  5IK9 A;  4NG6 A;  4HD1 A;  4KQU A;  3AQC B;  1VG7 A;  3WCD A;  4OGU A;  4E9U A;  4LUU A;  4GP1 A;  3ICZ A;  1PS1 A;  3VJC A;  3LLW A;  4LOB A;  1DI1 A;  4LZ0 A;  4LTV A;  4GAX A;  3OAB B;  5DHK A;  3NPR A;  5IMN A;  4KQS A;  3CKE A;  2E95 A;  3WCC A;  3Q30 A;  4LXW A;  3RMG A;  3WCI A;  5CG5 A;  1YYR A;  2O1O A;  1N20 A;  3N3D A;  4LLT A;  1WY0 A;  3WEI A;  4MC0 A;  2ZCS A;  4GP2 A;  3N0G A;  3EFQ A;  2Z7I A;  3VJB A;  3KRC A;  4F62 A;  2E8T A;  2Z4V A;  4KKM A;  3N6K F;  4P0V A;  1N23 A;  4Q23 A;  1UBV A;  2I19 A;  2F7M F;  4KUX A;  5IK0 A;  4FJQ A;  4KPJ A;  4NKE A;  4LTZ A;  4KQ5 A;  3M01 A;  5B01 A;  4XQR F;  3LG5 A;  4JXY A;  2F89 F;  2AZL A;  3Q2Z A;  4NFK F;  3WCE A;  3SDU A;  3WCB A;  3M9U A;  3ACY A;  4N1Z F;  3TC1 A;  2Q58 A;  2ONG A;  5IL8 A;  3RYE A;  2E8V A;  3AQB B;  4QPF A;  5EAS A;  4LZ3 A;  3ZOU A;  3P8L A;  5B0J A;  3W7F A;  3VJ8 A;  2Z50 A;  5DJR F;  1VG4 A;  4E9Z A;  2Z4W A;  1N24 A;  5E8K A;  5IKA A;  1EZF A;  4LPG F;  3N46 F;  5IL3 A;  5HN7 A;  3EZ3 A;  4F6X A;  1YHK A;  3V1V A;  3WJO A;  2E8W A;  3WEF A;  3AE0 A;  3LSN A;  1N1B A;  5DJP F;  3ZCD A;  3N5H F;  3KRA A;  4ZQ8 A;  3LMD A;  3PH7 A;  2PS7 A;  1N1Z A;  4H5D F;  3KRF A;  5DGN F;  5ILY A;  1YYQ A;  5DW7 A;  5ERM A;  3NRI A;  4H5C F;  3LGZ B;  5EAU A;  1UBW A;  5ILZ A;  3KBK A;  5ILH A;  2DH4 A;  2EWG A;  2Z4Y A;  5DGM F;  3BNX A;  3VJ9 A;  3OAC A;  2ZEV A;  4JZX A;  1YHM A;  2F9K F;  4WK5 A;  4KK2 A;  4EA2 A;  2FOR A;  5JV0 F;  4LZC A;  4DXJ A;  1FPS A;  3ACW A;  3P5R A;  2FTZ A;  3PYB A;  3KRC B;  3WC9 A;  1KIZ A;  3UCA A;  4RYP A;  3RBM A;  4KFA A;  1YYU A;  4LA5 A;  1UBX A;  3LJI A;  3ADZ A;  4RXC A;  1UBY A;  1RQJ A;  4KVD A;  3ASX A;  5JA0 F;  4DHD A;  4KPD A;  5H9D A;  2OPM A;  3WE9 A;  4GA3 A;  3S9V A;  4DZW A;  3WEG A;  2F8Z F;  1WKZ A;  5HN9 A;  2OA6 A;  4JZB A;  4OMH A;  2Z52 A;  4EA1 A;  3IPI A;  2E90 A;  5AYP A;  1HXA A;  5AEL A;  2AEL A;  1HXG A;  2OPN A;  3APZ A;  4KVW A;  4OKM A;  3SDQ A;  1V4K A;  3DYF A;  2E92 A;  3ICM A;  3P41 A;  4KWD A; 
#chains in the Genus database with same CATH topology
 5B00 A;  1VG6 A;  2ZCO A;  3DYG A;  3V1X A;  3CP6 A;  5JV2 F;  3WCL A;  3KRP A;  5C05 A;  4MC3 A;  3PKO A;  4EA0 A;  1RQI A;  4KVY A;  5IKH A;  5EAT A;  4DEM F;  5A0I A;  5DIQ F;  5HN8 A;  1KIY A;  5IMP A;  3WSA A;  2E93 A;  3NPK A;  4RXD A;  2PS8 A;  1VG2 A;  4H5E F;  1HX9 A;  3WCJ A;  5A0J A;  1WL3 A;  4LIX A;  4OKZ A;  3N3L F;  3KRA B;  3WCH A;  2J1P A;  3DYH A;  1V4E A;  4DWG A;  3KRF B;  5ER8 A;  2PS4 A;  4XQS F;  4N9U A;  2H8O A;  5ILI A;  3S4J A;  2J1O A;  2ZEU A;  5B02 A;  3SAE A;  3ACX A;  3BNY A;  3VJA A;  3QKC A;  5DJV F;  4JVJ F;  2AET A;  3OAC B;  5A0K A;  4PVY F;  4OMG A;  4DI5 A;  2VF6 A;  4MC8 A;  3RYW A;  2ZCR A;  3ZMC A;  4RXE A;  2ONH A;  2AZJ A;  1N21 A;  4LFV F;  2PS6 A;  4NKF A;  5ERO A;  2E94 A;  3WSB A;  4NUA A;  1YJ4 A;  1ZW5 A;  4K10 A;  3N49 F;  3V66 A;  2AEK A;  1WL2 A;  5AFX A;  4L2X F;  3PDE A;  3WCG A;  3TFN A;  3SDT A;  3MAV A;  5B0M A;  5E8H A;  3KRO A;  4E1E A;  3NF2 A;  3M00 A;  1YV5 A;  5IMI A;  3M02 A;  2Z4X A;  3MZV A;  5IN8 A;  1YHL A;  5DZ2 A;  3LOM A;  3LK5 A;  3N1W F;  3P8R A;  4LLS A;  3OAB A;  4LA6 A;  3P5P A;  5IK6 A;  5DGS F;  2AZK A;  4F6V A;  5B03 A;  4LPH F;  3LEE A;  1DGP A;  5DHI A;  3Q2Q A;  3PYA A;  2Q9Y A;  5JV1 F;  3G4F A;  5E8L A;  3SDV A;  5ILK A;  3M0G A;  2QIS A;  5B0L A;  3CC9 A;  3WCA A;  3N0F A;  1WL1 A;  3KRP B;  5I1U A;  3G4D A;  3LZ9 A;  1HM7 A;  1WMW A;  4JXN A;  3ICN A;  4PVX F;  4DWB A;  1JFG A;  2Q9Z A;  3WCM A;  3ICK A;  3ZL6 A;  1WL0 A;  3AQ0 A;  4RNQ A;  2E8X A;  2F8C F;  3TFV A;  2OGD A;  5CG6 A;  1V4J A;  2E4O A;  3WJN A;  3N1V F;  4LFE A;  4LFG A;  2PS5 A;  2P1C A;  2Q80 A;  2ZCQ A;  5ERN A;  3KB9 A;  3SDR A;  4FP4 A;  4XQT F;  3QQV A;  4NFI F;  3VJD A;  4NFJ F;  4KVI A;  4QXS F;  5AHU B;  3B7L A;  1HXC A;  2E8U A;  1YYT A;  2E91 A;  4RXA A;  1YYS A;  2F92 F;  5JUZ F;  3OYR A;  3WCF A;  2RAH A;  3EGT A;  3LGK A;  3LVS A;  3N45 F;  3IBA A;  1VG3 A;  3VJE A;  3WEH A;  1HM4 A;  3WEK A;  2Z78 A;  2Z4Z A;  2ZY1 A;  3N5J F;  1V4H A;  3ZMB A;  3Q1O A;  4JYX A;  5ILD A;  3WJK A;  1JFA A;  1V4I A;  1YQ7 A;  4UMJ A;  2Z7H A;  5B0K A;  5ILJ A;  3ID0 A;  3WEJ A;  5IVG A;  3TFP A;  2J5C A;  5B0I A;  5IM1 A;  5KSX F;  1N22 A;  4P0X A;  3TS7 A;  1RTR A;  3KRO B;  4P0W A;  5HNA A;  2F94 F;  3LDW A;  5IK9 A;  4NG6 A;  4HD1 A;  4KQU A;  3AQC B;  1VG7 A;  3WCD A;  4OGU A;  4E9U A;  4LUU A;  4GP1 A;  3ICZ A;  1PS1 A;  3VJC A;  3LLW A;  4LOB A;  1DI1 A;  4LZ0 A;  4LTV A;  4GAX A;  3OAB B;  5DHK A;  3NPR A;  5IMN A;  4KQS A;  3CKE A;  2E95 A;  3WCC A;  3Q30 A;  4LXW A;  3RMG A;  3WCI A;  5CG5 A;  1YYR A;  2O1O A;  1N20 A;  3N3D A;  4LLT A;  1WY0 A;  3WEI A;  4MC0 A;  2ZCS A;  4GP2 A;  3N0G A;  3EFQ A;  2Z7I A;  3VJB A;  3KRC A;  4F62 A;  2E8T A;  2Z4V A;  4KKM A;  3N6K F;  4P0V A;  1N23 A;  4Q23 A;  1UBV A;  2I19 A;  2F7M F;  4KUX A;  5IK0 A;  4FJQ A;  4KPJ A;  4NKE A;  4LTZ A;  4KQ5 A;  3M01 A;  5B01 A;  4XQR F;  3LG5 A;  4JXY A;  2F89 F;  2AZL A;  3Q2Z A;  4NFK F;  3WCE A;  3SDU A;  3WCB A;  3M9U A;  3ACY A;  4N1Z F;  3TC1 A;  2Q58 A;  2ONG A;  5IL8 A;  3RYE A;  2E8V A;  3AQB B;  4QPF A;  5EAS A;  4LZ3 A;  3ZOU A;  3P8L A;  5B0J A;  3W7F A;  3VJ8 A;  2Z50 A;  5DJR F;  1VG4 A;  4E9Z A;  2Z4W A;  1N24 A;  5E8K A;  5IKA A;  1EZF A;  4LPG F;  3N46 F;  5IL3 A;  5HN7 A;  3EZ3 A;  4F6X A;  1YHK A;  3V1V A;  3WJO A;  2E8W A;  3WEF A;  3AE0 A;  3LSN A;  1N1B A;  5DJP F;  3ZCD A;  3N5H F;  3KRA A;  4ZQ8 A;  3LMD A;  3PH7 A;  2PS7 A;  1N1Z A;  4H5D F;  3KRF A;  5DGN F;  5ILY A;  1YYQ A;  5DW7 A;  5ERM A;  3NRI A;  4H5C F;  3LGZ B;  5EAU A;  1UBW A;  5ILZ A;  3KBK A;  5ILH A;  2DH4 A;  2EWG A;  2Z4Y A;  5DGM F;  3BNX A;  3VJ9 A;  3OAC A;  2ZEV A;  4JZX A;  1YHM A;  2F9K F;  4WK5 A;  4KK2 A;  4EA2 A;  2FOR A;  5JV0 F;  4LZC A;  4DXJ A;  1FPS A;  3ACW A;  3P5R A;  2FTZ A;  3PYB A;  3KRC B;  3WC9 A;  1KIZ A;  3UCA A;  4RYP A;  3RBM A;  4KFA A;  1YYU A;  4LA5 A;  1UBX A;  3LJI A;  3ADZ A;  4RXC A;  1UBY A;  1RQJ A;  4KVD A;  3ASX A;  5JA0 F;  4DHD A;  4KPD A;  5H9D A;  2OPM A;  3WE9 A;  4GA3 A;  3S9V A;  4DZW A;  3WEG A;  2F8Z F;  1WKZ A;  5HN9 A;  2OA6 A;  4JZB A;  4OMH A;  2Z52 A;  4EA1 A;  3IPI A;  2E90 A;  5AYP A;  1HXA A;  5AEL A;  2AEL A;  1HXG A;  2OPN A;  3APZ A;  4KVW A;  4OKM A;  3SDQ A;  1V4K A;  3DYF A;  2E92 A;  3ICM A;  3P41 A;  4KWD A; 
#chains in the Genus database with same CATH homology
 5B00 A;  1VG6 A;  2ZCO A;  3DYG A;  3V1X A;  3CP6 A;  5JV2 F;  3WCL A;  3KRP A;  5C05 A;  4MC3 A;  3PKO A;  4EA0 A;  1RQI A;  4KVY A;  5IKH A;  5EAT A;  4DEM F;  5A0I A;  5DIQ F;  5HN8 A;  1KIY A;  5IMP A;  3WSA A;  2E93 A;  3NPK A;  4RXD A;  2PS8 A;  1VG2 A;  4H5E F;  1HX9 A;  3WCJ A;  5A0J A;  1WL3 A;  4LIX A;  4OKZ A;  3N3L F;  3KRA B;  3WCH A;  2J1P A;  3DYH A;  1V4E A;  4DWG A;  3KRF B;  5ER8 A;  2PS4 A;  4XQS F;  4N9U A;  2H8O A;  5ILI A;  3S4J A;  2J1O A;  2ZEU A;  5B02 A;  3SAE A;  3ACX A;  3BNY A;  3VJA A;  3QKC A;  5DJV F;  4JVJ F;  2AET A;  3OAC B;  5A0K A;  4PVY F;  4OMG A;  4DI5 A;  2VF6 A;  4MC8 A;  3RYW A;  2ZCR A;  3ZMC A;  4RXE A;  2ONH A;  2AZJ A;  1N21 A;  4LFV F;  2PS6 A;  4NKF A;  5ERO A;  2E94 A;  3WSB A;  4NUA A;  1YJ4 A;  1ZW5 A;  4K10 A;  3N49 F;  3V66 A;  2AEK A;  1WL2 A;  5AFX A;  4L2X F;  3PDE A;  3WCG A;  3TFN A;  3SDT A;  3MAV A;  5B0M A;  5E8H A;  3KRO A;  4E1E A;  3NF2 A;  3M00 A;  1YV5 A;  5IMI A;  3M02 A;  2Z4X A;  3MZV A;  5IN8 A;  1YHL A;  5DZ2 A;  3LOM A;  3LK5 A;  3N1W F;  3P8R A;  4LLS A;  3OAB A;  4LA6 A;  3P5P A;  5IK6 A;  5DGS F;  2AZK A;  4F6V A;  5B03 A;  4LPH F;  3LEE A;  1DGP A;  5DHI A;  3Q2Q A;  3PYA A;  2Q9Y A;  5JV1 F;  3G4F A;  5E8L A;  3SDV A;  5ILK A;  3M0G A;  2QIS A;  5B0L A;  3CC9 A;  3WCA A;  3N0F A;  1WL1 A;  3KRP B;  5I1U A;  3G4D A;  3LZ9 A;  1HM7 A;  1WMW A;  4JXN A;  3ICN A;  4PVX F;  4DWB A;  1JFG A;  2Q9Z A;  3WCM A;  3ICK A;  3ZL6 A;  1WL0 A;  3AQ0 A;  4RNQ A;  2E8X A;  2F8C F;  3TFV A;  2OGD A;  5CG6 A;  1V4J A;  2E4O A;  3WJN A;  3N1V F;  4LFE A;  4LFG A;  2PS5 A;  2P1C A;  2Q80 A;  2ZCQ A;  5ERN A;  3KB9 A;  3SDR A;  4FP4 A;  4XQT F;  3QQV A;  4NFI F;  3VJD A;  4NFJ F;  4KVI A;  4QXS F;  5AHU B;  3B7L A;  1HXC A;  2E8U A;  1YYT A;  2E91 A;  4RXA A;  1YYS A;  2F92 F;  5JUZ F;  3OYR A;  3WCF A;  2RAH A;  3EGT A;  3LGK A;  3LVS A;  3N45 F;  3IBA A;  1VG3 A;  3VJE A;  3WEH A;  1HM4 A;  3WEK A;  2Z78 A;  2Z4Z A;  2ZY1 A;  3N5J F;  1V4H A;  3ZMB A;  3Q1O A;  4JYX A;  5ILD A;  3WJK A;  1JFA A;  1V4I A;  1YQ7 A;  4UMJ A;  2Z7H A;  5B0K A;  5ILJ A;  3ID0 A;  3WEJ A;  5IVG A;  3TFP A;  2J5C A;  5B0I A;  5IM1 A;  5KSX F;  1N22 A;  4P0X A;  3TS7 A;  1RTR A;  3KRO B;  4P0W A;  5HNA A;  2F94 F;  3LDW A;  5IK9 A;  4NG6 A;  4HD1 A;  4KQU A;  3AQC B;  1VG7 A;  3WCD A;  4OGU A;  4E9U A;  4LUU A;  4GP1 A;  3ICZ A;  1PS1 A;  3VJC A;  3LLW A;  4LOB A;  1DI1 A;  4LZ0 A;  4LTV A;  4GAX A;  3OAB B;  5DHK A;  3NPR A;  5IMN A;  4KQS A;  3CKE A;  2E95 A;  3WCC A;  3Q30 A;  4LXW A;  3RMG A;  3WCI A;  5CG5 A;  1YYR A;  2O1O A;  1N20 A;  3N3D A;  4LLT A;  1WY0 A;  3WEI A;  4MC0 A;  2ZCS A;  4GP2 A;  3N0G A;  3EFQ A;  2Z7I A;  3VJB A;  3KRC A;  4F62 A;  2E8T A;  2Z4V A;  4KKM A;  3N6K F;  4P0V A;  1N23 A;  4Q23 A;  1UBV A;  2I19 A;  2F7M F;  4KUX A;  5IK0 A;  4FJQ A;  4KPJ A;  4NKE A;  4LTZ A;  4KQ5 A;  3M01 A;  5B01 A;  4XQR F;  3LG5 A;  4JXY A;  2F89 F;  2AZL A;  3Q2Z A;  4NFK F;  3WCE A;  3SDU A;  3WCB A;  3M9U A;  3ACY A;  4N1Z F;  3TC1 A;  2Q58 A;  2ONG A;  5IL8 A;  3RYE A;  2E8V A;  3AQB B;  4QPF A;  5EAS A;  4LZ3 A;  3ZOU A;  3P8L A;  5B0J A;  3W7F A;  3VJ8 A;  2Z50 A;  5DJR F;  1VG4 A;  4E9Z A;  2Z4W A;  1N24 A;  5E8K A;  5IKA A;  1EZF A;  4LPG F;  3N46 F;  5IL3 A;  5HN7 A;  3EZ3 A;  4F6X A;  1YHK A;  3V1V A;  3WJO A;  2E8W A;  3WEF A;  3AE0 A;  3LSN A;  1N1B A;  5DJP F;  3ZCD A;  3N5H F;  3KRA A;  4ZQ8 A;  3LMD A;  3PH7 A;  2PS7 A;  1N1Z A;  4H5D F;  3KRF A;  5DGN F;  5ILY A;  1YYQ A;  5DW7 A;  5ERM A;  3NRI A;  4H5C F;  3LGZ B;  5EAU A;  1UBW A;  5ILZ A;  3KBK A;  5ILH A;  2DH4 A;  2EWG A;  2Z4Y A;  5DGM F;  3BNX A;  3VJ9 A;  3OAC A;  2ZEV A;  4JZX A;  1YHM A;  2F9K F;  4WK5 A;  4KK2 A;  4EA2 A;  2FOR A;  5JV0 F;  4LZC A;  4DXJ A;  1FPS A;  3ACW A;  3P5R A;  2FTZ A;  3PYB A;  3KRC B;  3WC9 A;  1KIZ A;  3UCA A;  4RYP A;  3RBM A;  4KFA A;  1YYU A;  4LA5 A;  1UBX A;  3LJI A;  3ADZ A;  4RXC A;  1UBY A;  1RQJ A;  4KVD A;  3ASX A;  5JA0 F;  4DHD A;  4KPD A;  5H9D A;  2OPM A;  3WE9 A;  4GA3 A;  3S9V A;  4DZW A;  3WEG A;  2F8Z F;  1WKZ A;  5HN9 A;  2OA6 A;  4JZB A;  4OMH A;  2Z52 A;  4EA1 A;  3IPI A;  2E90 A;  5AYP A;  1HXA A;  5AEL A;  2AEL A;  1HXG A;  2OPN A;  3APZ A;  4KVW A;  4OKM A;  3SDQ A;  1V4K A;  3DYF A;  2E92 A;  3ICM A;  3P41 A;  4KWD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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