3WSBA

The tuberculosis drug sq109 inhibits trypanosoma cruzi cell proliferation and acts synergistically with posaconazole
Total Genus 138
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
138
sequence length
341
structure length
341
Chain Sequence
DEDLRFCYDILQAVSRSFAVVIMELDEEMRDAVCIFYLVLRALDTVEDDMSIPVEFKLRELPKFHEHLHDTTWCMSGVGVGRERELLERYTHVTRAYSRLGKAYQDVISGICERMANGMCDFLTRKVETKADYDLYCHYVAGLVGHGLTLLYVSSGLEDVRLADDLTNANHMGLFLQKTNIIRDFYEDICEVPPRVFWPREIWEKYTDDLHAFKDELHEAKAVECLNAMVADALVHVPHVVEYLASLRDPSVFAFSAIPQVMAMATLSLVFNNKDVFHTKVKTTRGATARIFHYSTELQATLQMLKTYTLRLAARMNAQDACYDRIEHLVNDAIRAMESHQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
molecule keywords Farnesyltransferase, putative
publication title The Tuberculosis Drug SQ109 Inhibits Trypanosoma cruzi Cell Proliferation and acts Synergistically with Posaconazole
rcsb
source organism Trypanosoma cruzi
total genus 138
structure length 341
sequence length 341
chains with identical sequence B, C, D
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2014-03-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3wsbA00
1RQJA 3WEHA 4KFAA 5DHIA 4H5CF 3KROA 2O1OA 5A0IA 5B01A 3N5HF 4NKEA 3SDTA 4FP4A 3MZVA 3WEIA 4PVXF 5IK0A 3ADZA 3NRIA 1N23A 4LXWA 4E9ZA 1UBXA 2ZCSA 3Q1OA 2Z4YA 4E1EA 4KPDA 2EWGA 3WCDA 3LOMA 4OKZA 3G4FA 3WSAA 2ZCRA 2Z4ZA 4MC0A 3N6KF 5DJPF 2OPNA 5IK6A 3WCGA 5ILDA 3KRFA 3ACXA 4FJQA 3ASXA 1YHLA 1WL0A 2F9KF 3VJBA 2AELA 2FORA 3PDEA 4OMGA 3ZL6A 3ICZA 3WEFA 3RBMA 4OMHA 3ZCDA 4UMJA 1WL1A 4JVJF 3NPKA 4KWDA 4P0WA 4LFGA 4NG6A 5IMPA 4DI5A 3BNXA 2Z50A 3WCAA 5JV2F 2OA6A 5B03A 4GP2A 5H9DA 3WCFA 3VJAA 1EZFA 3SDUA 3KRAA 4QXSF 4LUUA 5DHKA 2FTZA 3RYWA 5B00A 2E90A 2E93A 5DGSF 5B0MA 3WJOA 3Q30A 1HXCA 4MC8A 5C05A 3P8RA 1FPSA 3OACB 3WCBA 5IN8A 1RTRA 1YYSA 5DIQF 5ILJA 2PS4A 4QPFA 4JYXA 3CP6A 3TC1A 1V4IA 2E4OA 3OYRA 3P5RA 3DYHA 4LZCA 3LEEA 2E8VA 5B0KA 4LIXA 5B0LA 1WKZA 2E8UA 2E95A 4N1ZF 3AQ0A 4KVYA 2F94F 4PVYF 1YYQA 2AZJA 2F8ZF 3RYEA 1VG3A 4RXDA 5ERNA 3S4JA 5IKAA 1JFGA 5IL3A 5ILHA 1YJ4A 1YYUA 3KROB 3WC9A 4KQSA 1HXAA 4RNQA 5AYPA 3N1VF 3WEKA 3N3DA 4OKMA 1UBWA 3WCEA 3EFQA 4RXCA 5IVGA 3N1WF 4LOBA 2Z7IA 2AZLA 3UCAA 4KQUA 2AZKA 4XQRF 4DEMF 3PH7A 5ILZA 5ILYA 1WL3A 5JV0F 4LZ3A 3V66A 3BNYA 2PS8A 3Q2ZA 4EA2A 3PYAA 3EZ3A 1VG2A 4DHDA 5IK9A 5IM1A 3PKOA 3LGZB 4EA0A 1HX9A 5DZ2A 3V1XA 3KRFB 5EAUA 3WCHA 2E91A 3M01A 3W7FA 4JZBA 1KIZA 3NPRA 1YYRA 1ZW5A 2Q9ZA 1UBVA 3CC9A 2PS7A 4NFKF 3LMDA 5E8KA 5A0JA 2DH4A 2ZEUA 2Z7HA 2E8TA 3IPIA 3LLWA 1WL2A 3WCCA 3N49F 2OGDA 5B0IA 5IL8A 1YV5A 3SDRA 2PS5A 4NFIF 3VJEA 3Q2QA 5E8HA 3M02A 1N20A 2Z4VA 3CKEA 5HN9A 4NFJF 1N1BA 2E8WA 3OABA 3ZMCA 2E92A 5DJVF 3DYGA 2QISA 3AQCB 1YHMA 1V4KA 4KPJA 1VG6A 4KK2A 4P0VA 5DJRF 3LG5A 1HM4A 3SDVA 4HD1A 3KRPA 4LPHF 5AFXA 3MAVA 5E8LA 5ILIA 2ONGA 2RAHA 4XQSF 4JZXA 1WY0A 3LJIA 4LA5A 5JV1F 4NKFA 3S9VA 1JFAA 1VG4A 3B7LA 4RXEA 2E8XA 2F89F 5DGMF 3ICKA 4KVWA 4LA6A 3SDQA 3N45F 5HN7A 4F62A 3EGTA 1DGPA 3LSNA 3WEGA 3AQBB 3LK5A 3LDWA 3LZ9A 3G4DA 5AELA 3N5JF 1N24A 5HNAA 2PS6A 4N9UA 3KRCA 4H5EF 3ACYA 2I19A 1V4JA 2Z52A 4L2XF 1V4HA 4XQTF 1N1ZA 3N0GA 4DZWA 3ID0A 5B0JA 3WCJA 3TS7A 4EA1A 5B02A 1YQ7A 4JXYA 5AHUB 5CG6A 4GAXA 5JUZF 1YHKA 5ERMA 4F6VA 3WJKA 2Q9YA 4GP1A 3WCLA 2F92F 2Z4WA 5ER8A 3IBAA 1RQIA 3M9UA 5HN8A 3QQVA 2F7MF 4LTVA 3WSBA 3QKCA 2ZCQA 4LPGF 4WK5A 2ZEVA 3RMGA 2ONHA 3TFVA 1N21A 1DI1A 3VJ9A 3LVSA 3WCIA 2AETA 4ZQ8A 1VG7A 2ZY1A 5EASA 3NF2A 4MC3A 2OPMA 2E94A 4Q23A 2P1CA 4RXAA 5DGNF 5I1UA 5EATA 5IMIA 3V1VA 3VJ8A 3TFNA 3P5PA 1N22A 1HM7A 1KIYA 4K10A 2Q80A 4OGUA 4NUAA 5ILKA 5IKHA 3KRAB 2H8OA 2F8CF 3WEJA 3N46F 2J1OA 3ICMA 3WJNA 3OABB 5DW7A 4GA3A 2Q58A 3LGKA 2VF6A 1YYTA 5JA0F 1WMWA 3PYBA 3DYFA 3M00A 4F6XA 1UBYA 2J5CA 3KRPB 3SAEA 3M0GA 4KVIA 2ZCOA 1HXGA 4KQ5A 4DWGA 4E9UA 2AEKA 3TFPA 4P0XA 3KBKA 3OACA 5CG5A 3ZOUA 4KKMA 4DWBA 3VJDA 5KSXF 4RYPA 5EROA 3ZMBA 5A0KA 4DXJA 3WE9A 4KVDA 3KRCB 4LFEA 3APZA 3ICNA 3P41A 2Z4XA 4LFVF 3P8LA 5IMNA 4LLSA 4LLTA 1PS1A 4LZ0A 3VJCA 3AE0A 3N0FA 3KB9A 4KUXA 4JXNA 3N3LF 3ACWA 2J1PA 3WCMA 2Z78A 1V4EA 4LTZA 4H5DF
chains in the Genus database with same CATH superfamily
1RQJA 3WEHA 4KFAA 5DHIA 4H5CF 3KROA 2O1OA 5A0IA 5B01A 3N5HF 4NKEA 3SDTA 4FP4A 3MZVA 3WEIA 4PVXF 5IK0A 3ADZA 3NRIA 1N23A 4LXWA 4E9ZA 1UBXA 2ZCSA 3Q1OA 2Z4YA 4E1EA 4KPDA 2EWGA 3WCDA 3LOMA 4OKZA 3G4FA 3WSAA 2ZCRA 2Z4ZA 4MC0A 3N6KF 5DJPF 2OPNA 5IK6A 3WCGA 5ILDA 3KRFA 3ACXA 4FJQA 3ASXA 1YHLA 1WL0A 2F9KF 3VJBA 2AELA 2FORA 3PDEA 4OMGA 3ZL6A 3ICZA 3WEFA 3RBMA 4OMHA 3ZCDA 4UMJA 1WL1A 4JVJF 3NPKA 4KWDA 4P0WA 4LFGA 4NG6A 5IMPA 4DI5A 3BNXA 2Z50A 3WCAA 5JV2F 2OA6A 5B03A 4GP2A 5H9DA 3WCFA 3VJAA 1EZFA 3SDUA 3KRAA 4QXSF 4LUUA 5DHKA 2FTZA 3RYWA 5B00A 2E90A 2E93A 5DGSF 5B0MA 3WJOA 3Q30A 1HXCA 4MC8A 5C05A 3P8RA 1FPSA 3OACB 3WCBA 5IN8A 1RTRA 1YYSA 5DIQF 5ILJA 2PS4A 4QPFA 4JYXA 3CP6A 3TC1A 1V4IA 2E4OA 3OYRA 3P5RA 3DYHA 4LZCA 3LEEA 2E8VA 5B0KA 4LIXA 5B0LA 1WKZA 2E8UA 2E95A 4N1ZF 3AQ0A 4KVYA 2F94F 4PVYF 1YYQA 2AZJA 2F8ZF 3RYEA 1VG3A 4RXDA 5ERNA 3S4JA 5IKAA 1JFGA 5IL3A 5ILHA 1YJ4A 1YYUA 3KROB 3WC9A 4KQSA 1HXAA 4RNQA 5AYPA 3N1VF 3WEKA 3N3DA 4OKMA 1UBWA 3WCEA 3EFQA 4RXCA 5IVGA 3N1WF 4LOBA 2Z7IA 2AZLA 3UCAA 4KQUA 2AZKA 4XQRF 4DEMF 3PH7A 5ILZA 5ILYA 1WL3A 5JV0F 4LZ3A 3V66A 3BNYA 2PS8A 3Q2ZA 4EA2A 3PYAA 3EZ3A 1VG2A 4DHDA 5IK9A 5IM1A 3PKOA 3LGZB 4EA0A 1HX9A 5DZ2A 3V1XA 3KRFB 5EAUA 3WCHA 2E91A 3M01A 3W7FA 4JZBA 1KIZA 3NPRA 1YYRA 1ZW5A 2Q9ZA 1UBVA 3CC9A 2PS7A 4NFKF 3LMDA 5E8KA 5A0JA 2DH4A 2ZEUA 2Z7HA 2E8TA 3IPIA 3LLWA 1WL2A 3WCCA 3N49F 2OGDA 5B0IA 5IL8A 1YV5A 3SDRA 2PS5A 4NFIF 3VJEA 3Q2QA 5E8HA 3M02A 1N20A 2Z4VA 3CKEA 5HN9A 4NFJF 1N1BA 2E8WA 3OABA 3ZMCA 2E92A 5DJVF 3DYGA 2QISA 3AQCB 1YHMA 1V4KA 4KPJA 1VG6A 4KK2A 4P0VA 5DJRF 3LG5A 1HM4A 3SDVA 4HD1A 3KRPA 4LPHF 5AFXA 3MAVA 5E8LA 5ILIA 2ONGA 2RAHA 4XQSF 4JZXA 1WY0A 3LJIA 4LA5A 5JV1F 4NKFA 3S9VA 1JFAA 1VG4A 3B7LA 4RXEA 2E8XA 2F89F 5DGMF 3ICKA 4KVWA 4LA6A 3SDQA 3N45F 5HN7A 4F62A 3EGTA 1DGPA 3LSNA 3WEGA 3AQBB 3LK5A 3LDWA 3LZ9A 3G4DA 5AELA 3N5JF 1N24A 5HNAA 2PS6A 4N9UA 3KRCA 4H5EF 3ACYA 2I19A 1V4JA 2Z52A 4L2XF 1V4HA 4XQTF 1N1ZA 3N0GA 4DZWA 3ID0A 5B0JA 3WCJA 3TS7A 4EA1A 5B02A 1YQ7A 4JXYA 5AHUB 5CG6A 4GAXA 5JUZF 1YHKA 5ERMA 4F6VA 3WJKA 2Q9YA 4GP1A 3WCLA 2F92F 2Z4WA 5ER8A 3IBAA 1RQIA 3M9UA 5HN8A 3QQVA 2F7MF 4LTVA 3WSBA 3QKCA 2ZCQA 4LPGF 4WK5A 2ZEVA 3RMGA 2ONHA 3TFVA 1N21A 1DI1A 3VJ9A 3LVSA 3WCIA 2AETA 4ZQ8A 1VG7A 2ZY1A 5EASA 3NF2A 4MC3A 2OPMA 2E94A 4Q23A 2P1CA 4RXAA 5DGNF 5I1UA 5EATA 5IMIA 3V1VA 3VJ8A 3TFNA 3P5PA 1N22A 1HM7A 1KIYA 4K10A 2Q80A 4OGUA 4NUAA 5ILKA 5IKHA 3KRAB 2H8OA 2F8CF 3WEJA 3N46F 2J1OA 3ICMA 3WJNA 3OABB 5DW7A 4GA3A 2Q58A 3LGKA 2VF6A 1YYTA 5JA0F 1WMWA 3PYBA 3DYFA 3M00A 4F6XA 1UBYA 2J5CA 3KRPB 3SAEA 3M0GA 4KVIA 2ZCOA 1HXGA 4KQ5A 4DWGA 4E9UA 2AEKA 3TFPA 4P0XA 3KBKA 3OACA 5CG5A 3ZOUA 4KKMA 4DWBA 3VJDA 5KSXF 4RYPA 5EROA 3ZMBA 5A0KA 4DXJA 3WE9A 4KVDA 3KRCB 4LFEA 3APZA 3ICNA 3P41A 2Z4XA 4LFVF 3P8LA 5IMNA 4LLSA 4LLTA 1PS1A 4LZ0A 3VJCA 3AE0A 3N0FA 3KB9A 4KUXA 4JXNA 3N3LF 3ACWA 2J1PA 3WCMA 2Z78A 1V4EA 4LTZA 4H5DF
chains in the Genus database with same CATH topology
1RQJA 3WEHA 4KFAA 5DHIA 4H5CF 3KROA 2O1OA 5A0IA 5B01A 3N5HF 4NKEA 3SDTA 4FP4A 3MZVA 3WEIA 4PVXF 5IK0A 3ADZA 3NRIA 1N23A 4LXWA 4E9ZA 1UBXA 2ZCSA 3Q1OA 2Z4YA 4E1EA 4KPDA 2EWGA 3WCDA 3LOMA 4OKZA 3G4FA 3WSAA 2ZCRA 2Z4ZA 4MC0A 3N6KF 5DJPF 2OPNA 5IK6A 3WCGA 5ILDA 3KRFA 3ACXA 4FJQA 3ASXA 1YHLA 1WL0A 2F9KF 3VJBA 2AELA 2FORA 3PDEA 4OMGA 3ZL6A 3ICZA 3WEFA 3RBMA 4OMHA 3ZCDA 4UMJA 1WL1A 4JVJF 3NPKA 4KWDA 4P0WA 4LFGA 4NG6A 5IMPA 4DI5A 3BNXA 2Z50A 3WCAA 5JV2F 2OA6A 5B03A 4GP2A 5H9DA 3WCFA 3VJAA 1EZFA 3SDUA 3KRAA 4QXSF 4LUUA 5DHKA 2FTZA 3RYWA 5B00A 2E90A 2E93A 5DGSF 5B0MA 3WJOA 3Q30A 1HXCA 4MC8A 5C05A 3P8RA 1FPSA 3OACB 3WCBA 5IN8A 1RTRA 1YYSA 5DIQF 5ILJA 2PS4A 4QPFA 4JYXA 3CP6A 3TC1A 1V4IA 2E4OA 3OYRA 3P5RA 3DYHA 4LZCA 3LEEA 2E8VA 5B0KA 4LIXA 5B0LA 1WKZA 2E8UA 2E95A 4N1ZF 3AQ0A 4KVYA 2F94F 4PVYF 1YYQA 2AZJA 2F8ZF 3RYEA 1VG3A 4RXDA 5ERNA 3S4JA 5IKAA 1JFGA 5IL3A 5ILHA 1YJ4A 1YYUA 3KROB 3WC9A 4KQSA 1HXAA 4RNQA 5AYPA 3N1VF 3WEKA 3N3DA 4OKMA 1UBWA 3WCEA 3EFQA 4RXCA 5IVGA 3N1WF 4LOBA 2Z7IA 2AZLA 3UCAA 4KQUA 2AZKA 4XQRF 4DEMF 3PH7A 5ILZA 5ILYA 1WL3A 5JV0F 4LZ3A 3V66A 3BNYA 2PS8A 3Q2ZA 4EA2A 3PYAA 3EZ3A 1VG2A 4DHDA 5IK9A 5IM1A 3PKOA 3LGZB 4EA0A 1HX9A 5DZ2A 3V1XA 3KRFB 5EAUA 3WCHA 2E91A 3M01A 3W7FA 4JZBA 1KIZA 3NPRA 1YYRA 1ZW5A 2Q9ZA 1UBVA 3CC9A 2PS7A 4NFKF 3LMDA 5E8KA 5A0JA 2DH4A 2ZEUA 2Z7HA 2E8TA 3IPIA 3LLWA 1WL2A 3WCCA 3N49F 2OGDA 5B0IA 5IL8A 1YV5A 3SDRA 2PS5A 4NFIF 3VJEA 3Q2QA 5E8HA 3M02A 1N20A 2Z4VA 3CKEA 5HN9A 4NFJF 1N1BA 2E8WA 3OABA 3ZMCA 2E92A 5DJVF 3DYGA 2QISA 3AQCB 1YHMA 1V4KA 4KPJA 1VG6A 4KK2A 4P0VA 5DJRF 3LG5A 1HM4A 3SDVA 4HD1A 3KRPA 4LPHF 5AFXA 3MAVA 5E8LA 5ILIA 2ONGA 2RAHA 4XQSF 4JZXA 1WY0A 3LJIA 4LA5A 5JV1F 4NKFA 3S9VA 1JFAA 1VG4A 3B7LA 4RXEA 2E8XA 2F89F 5DGMF 3ICKA 4KVWA 4LA6A 3SDQA 3N45F 5HN7A 4F62A 3EGTA 1DGPA 3LSNA 3WEGA 3AQBB 3LK5A 3LDWA 3LZ9A 3G4DA 5AELA 3N5JF 1N24A 5HNAA 2PS6A 4N9UA 3KRCA 4H5EF 3ACYA 2I19A 1V4JA 2Z52A 4L2XF 1V4HA 4XQTF 1N1ZA 3N0GA 4DZWA 3ID0A 5B0JA 3WCJA 3TS7A 4EA1A 5B02A 1YQ7A 4JXYA 5AHUB 5CG6A 4GAXA 5JUZF 1YHKA 5ERMA 4F6VA 3WJKA 2Q9YA 4GP1A 3WCLA 2F92F 2Z4WA 5ER8A 3IBAA 1RQIA 3M9UA 5HN8A 3QQVA 2F7MF 4LTVA 3WSBA 3QKCA 2ZCQA 4LPGF 4WK5A 2ZEVA 3RMGA 2ONHA 3TFVA 1N21A 1DI1A 3VJ9A 3LVSA 3WCIA 2AETA 4ZQ8A 1VG7A 2ZY1A 5EASA 3NF2A 4MC3A 2OPMA 2E94A 4Q23A 2P1CA 4RXAA 5DGNF 5I1UA 5EATA 5IMIA 3V1VA 3VJ8A 3TFNA 3P5PA 1N22A 1HM7A 1KIYA 4K10A 2Q80A 4OGUA 4NUAA 5ILKA 5IKHA 3KRAB 2H8OA 2F8CF 3WEJA 3N46F 2J1OA 3ICMA 3WJNA 3OABB 5DW7A 4GA3A 2Q58A 3LGKA 2VF6A 1YYTA 5JA0F 1WMWA 3PYBA 3DYFA 3M00A 4F6XA 1UBYA 2J5CA 3KRPB 3SAEA 3M0GA 4KVIA 2ZCOA 1HXGA 4KQ5A 4DWGA 4E9UA 2AEKA 3TFPA 4P0XA 3KBKA 3OACA 5CG5A 3ZOUA 4KKMA 4DWBA 3VJDA 5KSXF 4RYPA 5EROA 3ZMBA 5A0KA 4DXJA 3WE9A 4KVDA 3KRCB 4LFEA 3APZA 3ICNA 3P41A 2Z4XA 4LFVF 3P8LA 5IMNA 4LLSA 4LLTA 1PS1A 4LZ0A 3VJCA 3AE0A 3N0FA 3KB9A 4KUXA 4JXNA 3N3LF 3ACWA 2J1PA 3WCMA 2Z78A 1V4EA 4LTZA 4H5DF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RQJ A;  3WEH A;  4KFA A;  5DHI A;  4H5C F;  3KRO A;  2O1O A;  5A0I A;  5B01 A;  3N5H F;  4NKE A;  3SDT A;  4FP4 A;  3MZV A;  3WEI A;  4PVX F;  5IK0 A;  3ADZ A;  3NRI A;  1N23 A;  4LXW A;  4E9Z A;  1UBX A;  2ZCS A;  3Q1O A;  2Z4Y A;  4E1E A;  4KPD A;  2EWG A;  3WCD A;  3LOM A;  4OKZ A;  3G4F A;  3WSA A;  2ZCR A;  2Z4Z A;  4MC0 A;  3N6K F;  5DJP F;  2OPN A;  5IK6 A;  3WCG A;  5ILD A;  3KRF A;  3ACX A;  4FJQ A;  3ASX A;  1YHL A;  1WL0 A;  2F9K F;  3VJB A;  2AEL A;  2FOR A;  3PDE A;  4OMG A;  3ZL6 A;  3ICZ A;  3WEF A;  3RBM A;  4OMH A;  3ZCD A;  4UMJ A;  1WL1 A;  4JVJ F;  3NPK A;  4KWD A;  4P0W A;  4LFG A;  4NG6 A;  5IMP A;  4DI5 A;  3BNX A;  2Z50 A;  3WCA A;  5JV2 F;  2OA6 A;  5B03 A;  4GP2 A;  5H9D A;  3WCF A;  3VJA A;  1EZF A;  3SDU A;  3KRA A;  4QXS F;  4LUU A;  5DHK A;  2FTZ A;  3RYW A;  5B00 A;  2E90 A;  2E93 A;  5DGS F;  5B0M A;  3WJO A;  3Q30 A;  1HXC A;  4MC8 A;  5C05 A;  3P8R A;  1FPS A;  3OAC B;  3WCB A;  5IN8 A;  1RTR A;  1YYS A;  5DIQ F;  5ILJ A;  2PS4 A;  4QPF A;  4JYX A;  3CP6 A;  3TC1 A;  1V4I A;  2E4O A;  3OYR A;  3P5R A;  3DYH A;  4LZC A;  3LEE A;  2E8V A;  5B0K A;  4LIX A;  5B0L A;  1WKZ A;  2E8U A;  2E95 A;  4N1Z F;  3AQ0 A;  4KVY A;  2F94 F;  4PVY F;  1YYQ A;  2AZJ A;  2F8Z F;  3RYE A;  1VG3 A;  4RXD A;  5ERN A;  3S4J A;  5IKA A;  1JFG A;  5IL3 A;  5ILH A;  1YJ4 A;  1YYU A;  3KRO B;  3WC9 A;  4KQS A;  1HXA A;  4RNQ A;  5AYP A;  3N1V F;  3WEK A;  3N3D A;  4OKM A;  1UBW A;  3WCE A;  3EFQ A;  4RXC A;  5IVG A;  3N1W F;  4LOB A;  2Z7I A;  2AZL A;  3UCA A;  4KQU A;  2AZK A;  4XQR F;  4DEM F;  3PH7 A;  5ILZ A;  5ILY A;  1WL3 A;  5JV0 F;  4LZ3 A;  3V66 A;  3BNY A;  2PS8 A;  3Q2Z A;  4EA2 A;  3PYA A;  3EZ3 A;  1VG2 A;  4DHD A;  5IK9 A;  5IM1 A;  3PKO A;  3LGZ B;  4EA0 A;  1HX9 A;  5DZ2 A;  3V1X A;  3KRF B;  5EAU A;  3WCH A;  2E91 A;  3M01 A;  3W7F A;  4JZB A;  1KIZ A;  3NPR A;  1YYR A;  1ZW5 A;  2Q9Z A;  1UBV A;  3CC9 A;  2PS7 A;  4NFK F;  3LMD A;  5E8K A;  5A0J A;  2DH4 A;  2ZEU A;  2Z7H A;  2E8T A;  3IPI A;  3LLW A;  1WL2 A;  3WCC A;  3N49 F;  2OGD A;  5B0I A;  5IL8 A;  1YV5 A;  3SDR A;  2PS5 A;  4NFI F;  3VJE A;  3Q2Q A;  5E8H A;  3M02 A;  1N20 A;  2Z4V A;  3CKE A;  5HN9 A;  4NFJ F;  1N1B A;  2E8W A;  3OAB A;  3ZMC A;  2E92 A;  5DJV F;  3DYG A;  2QIS A;  3AQC B;  1YHM A;  1V4K A;  4KPJ A;  1VG6 A;  4KK2 A;  4P0V A;  5DJR F;  3LG5 A;  1HM4 A;  3SDV A;  4HD1 A;  3KRP A;  4LPH F;  5AFX A;  3MAV A;  5E8L A;  5ILI A;  2ONG A;  2RAH A;  4XQS F;  4JZX A;  1WY0 A;  3LJI A;  4LA5 A;  5JV1 F;  4NKF A;  3S9V A;  1JFA A;  1VG4 A;  3B7L A;  4RXE A;  2E8X A;  2F89 F;  5DGM F;  3ICK A;  4KVW A;  4LA6 A;  3SDQ A;  3N45 F;  5HN7 A;  4F62 A;  3EGT A;  1DGP A;  3LSN A;  3WEG A;  3AQB B;  3LK5 A;  3LDW A;  3LZ9 A;  3G4D A;  5AEL A;  3N5J F;  1N24 A;  5HNA A;  2PS6 A;  4N9U A;  3KRC A;  4H5E F;  3ACY A;  2I19 A;  1V4J A;  2Z52 A;  4L2X F;  1V4H A;  4XQT F;  1N1Z A;  3N0G A;  4DZW A;  3ID0 A;  5B0J A;  3WCJ A;  3TS7 A;  4EA1 A;  5B02 A;  1YQ7 A;  4JXY A;  5AHU B;  5CG6 A;  4GAX A;  5JUZ F;  1YHK A;  5ERM A;  4F6V A;  3WJK A;  2Q9Y A;  4GP1 A;  3WCL A;  2F92 F;  2Z4W A;  5ER8 A;  3IBA A;  1RQI A;  3M9U A;  5HN8 A;  3QQV A;  2F7M F;  4LTV A;  3WSB A;  3QKC A;  2ZCQ A;  4LPG F;  4WK5 A;  2ZEV A;  3RMG A;  2ONH A;  3TFV A;  1N21 A;  1DI1 A;  3VJ9 A;  3LVS A;  3WCI A;  2AET A;  4ZQ8 A;  1VG7 A;  2ZY1 A;  5EAS A;  3NF2 A;  4MC3 A;  2OPM A;  2E94 A;  4Q23 A;  2P1C A;  4RXA A;  5DGN F;  5I1U A;  5EAT A;  5IMI A;  3V1V A;  3VJ8 A;  3TFN A;  3P5P A;  1N22 A;  1HM7 A;  1KIY A;  4K10 A;  2Q80 A;  4OGU A;  4NUA A;  5ILK A;  5IKH A;  3KRA B;  2H8O A;  2F8C F;  3WEJ A;  3N46 F;  2J1O A;  3ICM A;  3WJN A;  3OAB B;  5DW7 A;  4GA3 A;  2Q58 A;  3LGK A;  2VF6 A;  1YYT A;  5JA0 F;  1WMW A;  3PYB A;  3DYF A;  3M00 A;  4F6X A;  1UBY A;  2J5C A;  3KRP B;  3SAE A;  3M0G A;  4KVI A;  2ZCO A;  1HXG A;  4KQ5 A;  4DWG A;  4E9U A;  2AEK A;  3TFP A;  4P0X A;  3KBK A;  3OAC A;  5CG5 A;  3ZOU A;  4KKM A;  4DWB A;  3VJD A;  5KSX F;  4RYP A;  5ERO A;  3ZMB A;  5A0K A;  4DXJ A;  3WE9 A;  4KVD A;  3KRC B;  4LFE A;  3APZ A;  3ICN A;  3P41 A;  2Z4X A;  4LFV F;  3P8L A;  5IMN A;  4LLS A;  4LLT A;  1PS1 A;  4LZ0 A;  3VJC A;  3AE0 A;  3N0F A;  3KB9 A;  4KUX A;  4JXN A;  3N3L F;  3ACW A;  2J1P A;  3WCM A;  2Z78 A;  1V4E A;  4LTZ A;  4H5D F; 
#chains in the Genus database with same CATH topology
 1RQJ A;  3WEH A;  4KFA A;  5DHI A;  4H5C F;  3KRO A;  2O1O A;  5A0I A;  5B01 A;  3N5H F;  4NKE A;  3SDT A;  4FP4 A;  3MZV A;  3WEI A;  4PVX F;  5IK0 A;  3ADZ A;  3NRI A;  1N23 A;  4LXW A;  4E9Z A;  1UBX A;  2ZCS A;  3Q1O A;  2Z4Y A;  4E1E A;  4KPD A;  2EWG A;  3WCD A;  3LOM A;  4OKZ A;  3G4F A;  3WSA A;  2ZCR A;  2Z4Z A;  4MC0 A;  3N6K F;  5DJP F;  2OPN A;  5IK6 A;  3WCG A;  5ILD A;  3KRF A;  3ACX A;  4FJQ A;  3ASX A;  1YHL A;  1WL0 A;  2F9K F;  3VJB A;  2AEL A;  2FOR A;  3PDE A;  4OMG A;  3ZL6 A;  3ICZ A;  3WEF A;  3RBM A;  4OMH A;  3ZCD A;  4UMJ A;  1WL1 A;  4JVJ F;  3NPK A;  4KWD A;  4P0W A;  4LFG A;  4NG6 A;  5IMP A;  4DI5 A;  3BNX A;  2Z50 A;  3WCA A;  5JV2 F;  2OA6 A;  5B03 A;  4GP2 A;  5H9D A;  3WCF A;  3VJA A;  1EZF A;  3SDU A;  3KRA A;  4QXS F;  4LUU A;  5DHK A;  2FTZ A;  3RYW A;  5B00 A;  2E90 A;  2E93 A;  5DGS F;  5B0M A;  3WJO A;  3Q30 A;  1HXC A;  4MC8 A;  5C05 A;  3P8R A;  1FPS A;  3OAC B;  3WCB A;  5IN8 A;  1RTR A;  1YYS A;  5DIQ F;  5ILJ A;  2PS4 A;  4QPF A;  4JYX A;  3CP6 A;  3TC1 A;  1V4I A;  2E4O A;  3OYR A;  3P5R A;  3DYH A;  4LZC A;  3LEE A;  2E8V A;  5B0K A;  4LIX A;  5B0L A;  1WKZ A;  2E8U A;  2E95 A;  4N1Z F;  3AQ0 A;  4KVY A;  2F94 F;  4PVY F;  1YYQ A;  2AZJ A;  2F8Z F;  3RYE A;  1VG3 A;  4RXD A;  5ERN A;  3S4J A;  5IKA A;  1JFG A;  5IL3 A;  5ILH A;  1YJ4 A;  1YYU A;  3KRO B;  3WC9 A;  4KQS A;  1HXA A;  4RNQ A;  5AYP A;  3N1V F;  3WEK A;  3N3D A;  4OKM A;  1UBW A;  3WCE A;  3EFQ A;  4RXC A;  5IVG A;  3N1W F;  4LOB A;  2Z7I A;  2AZL A;  3UCA A;  4KQU A;  2AZK A;  4XQR F;  4DEM F;  3PH7 A;  5ILZ A;  5ILY A;  1WL3 A;  5JV0 F;  4LZ3 A;  3V66 A;  3BNY A;  2PS8 A;  3Q2Z A;  4EA2 A;  3PYA A;  3EZ3 A;  1VG2 A;  4DHD A;  5IK9 A;  5IM1 A;  3PKO A;  3LGZ B;  4EA0 A;  1HX9 A;  5DZ2 A;  3V1X A;  3KRF B;  5EAU A;  3WCH A;  2E91 A;  3M01 A;  3W7F A;  4JZB A;  1KIZ A;  3NPR A;  1YYR A;  1ZW5 A;  2Q9Z A;  1UBV A;  3CC9 A;  2PS7 A;  4NFK F;  3LMD A;  5E8K A;  5A0J A;  2DH4 A;  2ZEU A;  2Z7H A;  2E8T A;  3IPI A;  3LLW A;  1WL2 A;  3WCC A;  3N49 F;  2OGD A;  5B0I A;  5IL8 A;  1YV5 A;  3SDR A;  2PS5 A;  4NFI F;  3VJE A;  3Q2Q A;  5E8H A;  3M02 A;  1N20 A;  2Z4V A;  3CKE A;  5HN9 A;  4NFJ F;  1N1B A;  2E8W A;  3OAB A;  3ZMC A;  2E92 A;  5DJV F;  3DYG A;  2QIS A;  3AQC B;  1YHM A;  1V4K A;  4KPJ A;  1VG6 A;  4KK2 A;  4P0V A;  5DJR F;  3LG5 A;  1HM4 A;  3SDV A;  4HD1 A;  3KRP A;  4LPH F;  5AFX A;  3MAV A;  5E8L A;  5ILI A;  2ONG A;  2RAH A;  4XQS F;  4JZX A;  1WY0 A;  3LJI A;  4LA5 A;  5JV1 F;  4NKF A;  3S9V A;  1JFA A;  1VG4 A;  3B7L A;  4RXE A;  2E8X A;  2F89 F;  5DGM F;  3ICK A;  4KVW A;  4LA6 A;  3SDQ A;  3N45 F;  5HN7 A;  4F62 A;  3EGT A;  1DGP A;  3LSN A;  3WEG A;  3AQB B;  3LK5 A;  3LDW A;  3LZ9 A;  3G4D A;  5AEL A;  3N5J F;  1N24 A;  5HNA A;  2PS6 A;  4N9U A;  3KRC A;  4H5E F;  3ACY A;  2I19 A;  1V4J A;  2Z52 A;  4L2X F;  1V4H A;  4XQT F;  1N1Z A;  3N0G A;  4DZW A;  3ID0 A;  5B0J A;  3WCJ A;  3TS7 A;  4EA1 A;  5B02 A;  1YQ7 A;  4JXY A;  5AHU B;  5CG6 A;  4GAX A;  5JUZ F;  1YHK A;  5ERM A;  4F6V A;  3WJK A;  2Q9Y A;  4GP1 A;  3WCL A;  2F92 F;  2Z4W A;  5ER8 A;  3IBA A;  1RQI A;  3M9U A;  5HN8 A;  3QQV A;  2F7M F;  4LTV A;  3WSB A;  3QKC A;  2ZCQ A;  4LPG F;  4WK5 A;  2ZEV A;  3RMG A;  2ONH A;  3TFV A;  1N21 A;  1DI1 A;  3VJ9 A;  3LVS A;  3WCI A;  2AET A;  4ZQ8 A;  1VG7 A;  2ZY1 A;  5EAS A;  3NF2 A;  4MC3 A;  2OPM A;  2E94 A;  4Q23 A;  2P1C A;  4RXA A;  5DGN F;  5I1U A;  5EAT A;  5IMI A;  3V1V A;  3VJ8 A;  3TFN A;  3P5P A;  1N22 A;  1HM7 A;  1KIY A;  4K10 A;  2Q80 A;  4OGU A;  4NUA A;  5ILK A;  5IKH A;  3KRA B;  2H8O A;  2F8C F;  3WEJ A;  3N46 F;  2J1O A;  3ICM A;  3WJN A;  3OAB B;  5DW7 A;  4GA3 A;  2Q58 A;  3LGK A;  2VF6 A;  1YYT A;  5JA0 F;  1WMW A;  3PYB A;  3DYF A;  3M00 A;  4F6X A;  1UBY A;  2J5C A;  3KRP B;  3SAE A;  3M0G A;  4KVI A;  2ZCO A;  1HXG A;  4KQ5 A;  4DWG A;  4E9U A;  2AEK A;  3TFP A;  4P0X A;  3KBK A;  3OAC A;  5CG5 A;  3ZOU A;  4KKM A;  4DWB A;  3VJD A;  5KSX F;  4RYP A;  5ERO A;  3ZMB A;  5A0K A;  4DXJ A;  3WE9 A;  4KVD A;  3KRC B;  4LFE A;  3APZ A;  3ICN A;  3P41 A;  2Z4X A;  4LFV F;  3P8L A;  5IMN A;  4LLS A;  4LLT A;  1PS1 A;  4LZ0 A;  3VJC A;  3AE0 A;  3N0F A;  3KB9 A;  4KUX A;  4JXN A;  3N3L F;  3ACW A;  2J1P A;  3WCM A;  2Z78 A;  1V4E A;  4LTZ A;  4H5D F; 
#chains in the Genus database with same CATH homology
 1RQJ A;  3WEH A;  4KFA A;  5DHI A;  4H5C F;  3KRO A;  2O1O A;  5A0I A;  5B01 A;  3N5H F;  4NKE A;  3SDT A;  4FP4 A;  3MZV A;  3WEI A;  4PVX F;  5IK0 A;  3ADZ A;  3NRI A;  1N23 A;  4LXW A;  4E9Z A;  1UBX A;  2ZCS A;  3Q1O A;  2Z4Y A;  4E1E A;  4KPD A;  2EWG A;  3WCD A;  3LOM A;  4OKZ A;  3G4F A;  3WSA A;  2ZCR A;  2Z4Z A;  4MC0 A;  3N6K F;  5DJP F;  2OPN A;  5IK6 A;  3WCG A;  5ILD A;  3KRF A;  3ACX A;  4FJQ A;  3ASX A;  1YHL A;  1WL0 A;  2F9K F;  3VJB A;  2AEL A;  2FOR A;  3PDE A;  4OMG A;  3ZL6 A;  3ICZ A;  3WEF A;  3RBM A;  4OMH A;  3ZCD A;  4UMJ A;  1WL1 A;  4JVJ F;  3NPK A;  4KWD A;  4P0W A;  4LFG A;  4NG6 A;  5IMP A;  4DI5 A;  3BNX A;  2Z50 A;  3WCA A;  5JV2 F;  2OA6 A;  5B03 A;  4GP2 A;  5H9D A;  3WCF A;  3VJA A;  1EZF A;  3SDU A;  3KRA A;  4QXS F;  4LUU A;  5DHK A;  2FTZ A;  3RYW A;  5B00 A;  2E90 A;  2E93 A;  5DGS F;  5B0M A;  3WJO A;  3Q30 A;  1HXC A;  4MC8 A;  5C05 A;  3P8R A;  1FPS A;  3OAC B;  3WCB A;  5IN8 A;  1RTR A;  1YYS A;  5DIQ F;  5ILJ A;  2PS4 A;  4QPF A;  4JYX A;  3CP6 A;  3TC1 A;  1V4I A;  2E4O A;  3OYR A;  3P5R A;  3DYH A;  4LZC A;  3LEE A;  2E8V A;  5B0K A;  4LIX A;  5B0L A;  1WKZ A;  2E8U A;  2E95 A;  4N1Z F;  3AQ0 A;  4KVY A;  2F94 F;  4PVY F;  1YYQ A;  2AZJ A;  2F8Z F;  3RYE A;  1VG3 A;  4RXD A;  5ERN A;  3S4J A;  5IKA A;  1JFG A;  5IL3 A;  5ILH A;  1YJ4 A;  1YYU A;  3KRO B;  3WC9 A;  4KQS A;  1HXA A;  4RNQ A;  5AYP A;  3N1V F;  3WEK A;  3N3D A;  4OKM A;  1UBW A;  3WCE A;  3EFQ A;  4RXC A;  5IVG A;  3N1W F;  4LOB A;  2Z7I A;  2AZL A;  3UCA A;  4KQU A;  2AZK A;  4XQR F;  4DEM F;  3PH7 A;  5ILZ A;  5ILY A;  1WL3 A;  5JV0 F;  4LZ3 A;  3V66 A;  3BNY A;  2PS8 A;  3Q2Z A;  4EA2 A;  3PYA A;  3EZ3 A;  1VG2 A;  4DHD A;  5IK9 A;  5IM1 A;  3PKO A;  3LGZ B;  4EA0 A;  1HX9 A;  5DZ2 A;  3V1X A;  3KRF B;  5EAU A;  3WCH A;  2E91 A;  3M01 A;  3W7F A;  4JZB A;  1KIZ A;  3NPR A;  1YYR A;  1ZW5 A;  2Q9Z A;  1UBV A;  3CC9 A;  2PS7 A;  4NFK F;  3LMD A;  5E8K A;  5A0J A;  2DH4 A;  2ZEU A;  2Z7H A;  2E8T A;  3IPI A;  3LLW A;  1WL2 A;  3WCC A;  3N49 F;  2OGD A;  5B0I A;  5IL8 A;  1YV5 A;  3SDR A;  2PS5 A;  4NFI F;  3VJE A;  3Q2Q A;  5E8H A;  3M02 A;  1N20 A;  2Z4V A;  3CKE A;  5HN9 A;  4NFJ F;  1N1B A;  2E8W A;  3OAB A;  3ZMC A;  2E92 A;  5DJV F;  3DYG A;  2QIS A;  3AQC B;  1YHM A;  1V4K A;  4KPJ A;  1VG6 A;  4KK2 A;  4P0V A;  5DJR F;  3LG5 A;  1HM4 A;  3SDV A;  4HD1 A;  3KRP A;  4LPH F;  5AFX A;  3MAV A;  5E8L A;  5ILI A;  2ONG A;  2RAH A;  4XQS F;  4JZX A;  1WY0 A;  3LJI A;  4LA5 A;  5JV1 F;  4NKF A;  3S9V A;  1JFA A;  1VG4 A;  3B7L A;  4RXE A;  2E8X A;  2F89 F;  5DGM F;  3ICK A;  4KVW A;  4LA6 A;  3SDQ A;  3N45 F;  5HN7 A;  4F62 A;  3EGT A;  1DGP A;  3LSN A;  3WEG A;  3AQB B;  3LK5 A;  3LDW A;  3LZ9 A;  3G4D A;  5AEL A;  3N5J F;  1N24 A;  5HNA A;  2PS6 A;  4N9U A;  3KRC A;  4H5E F;  3ACY A;  2I19 A;  1V4J A;  2Z52 A;  4L2X F;  1V4H A;  4XQT F;  1N1Z A;  3N0G A;  4DZW A;  3ID0 A;  5B0J A;  3WCJ A;  3TS7 A;  4EA1 A;  5B02 A;  1YQ7 A;  4JXY A;  5AHU B;  5CG6 A;  4GAX A;  5JUZ F;  1YHK A;  5ERM A;  4F6V A;  3WJK A;  2Q9Y A;  4GP1 A;  3WCL A;  2F92 F;  2Z4W A;  5ER8 A;  3IBA A;  1RQI A;  3M9U A;  5HN8 A;  3QQV A;  2F7M F;  4LTV A;  3WSB A;  3QKC A;  2ZCQ A;  4LPG F;  4WK5 A;  2ZEV A;  3RMG A;  2ONH A;  3TFV A;  1N21 A;  1DI1 A;  3VJ9 A;  3LVS A;  3WCI A;  2AET A;  4ZQ8 A;  1VG7 A;  2ZY1 A;  5EAS A;  3NF2 A;  4MC3 A;  2OPM A;  2E94 A;  4Q23 A;  2P1C A;  4RXA A;  5DGN F;  5I1U A;  5EAT A;  5IMI A;  3V1V A;  3VJ8 A;  3TFN A;  3P5P A;  1N22 A;  1HM7 A;  1KIY A;  4K10 A;  2Q80 A;  4OGU A;  4NUA A;  5ILK A;  5IKH A;  3KRA B;  2H8O A;  2F8C F;  3WEJ A;  3N46 F;  2J1O A;  3ICM A;  3WJN A;  3OAB B;  5DW7 A;  4GA3 A;  2Q58 A;  3LGK A;  2VF6 A;  1YYT A;  5JA0 F;  1WMW A;  3PYB A;  3DYF A;  3M00 A;  4F6X A;  1UBY A;  2J5C A;  3KRP B;  3SAE A;  3M0G A;  4KVI A;  2ZCO A;  1HXG A;  4KQ5 A;  4DWG A;  4E9U A;  2AEK A;  3TFP A;  4P0X A;  3KBK A;  3OAC A;  5CG5 A;  3ZOU A;  4KKM A;  4DWB A;  3VJD A;  5KSX F;  4RYP A;  5ERO A;  3ZMB A;  5A0K A;  4DXJ A;  3WE9 A;  4KVD A;  3KRC B;  4LFE A;  3APZ A;  3ICN A;  3P41 A;  2Z4X A;  4LFV F;  3P8L A;  5IMN A;  4LLS A;  4LLT A;  1PS1 A;  4LZ0 A;  3VJC A;  3AE0 A;  3N0F A;  3KB9 A;  4KUX A;  4JXN A;  3N3L F;  3ACW A;  2J1P A;  3WCM A;  2Z78 A;  1V4E A;  4LTZ A;  4H5D F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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