4H5DF

Crystal structure of human fpps in ternary complex with ys0470 and inorganic pyrophosphate
Total Genus 139
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
139
sequence length
346
structure length
346
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Farnesyl pyrophosphate synthase
publication title Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase/transferase inhibitor
total genus 139
structure length 346
sequence length 346
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2012-09-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4h5dF00
3AQBB 2AZJA 3KRPA 5IK0A 1YQ7A 4DHDA 1N1BA 5ILKA 5DW7A 3M9UA 4DEMF 3G4DA 2PS8A 4LXWA 4XQSF 5AELA 4MC3A 3ID0A 4KUXA 3WC9A 1N23A 4FP4A 4LA6A 4NFJF 5JV1F 4P0XA 3SDTA 5B0JA 2OPNA 1N1ZA 2DH4A 3N49F 3WCJA 3TFVA 4ZQ8A 3AQCB 5IK9A 5IMPA 3SDVA 3ZMBA 2Q9ZA 5B01A 5ERMA 4EA0A 1HM7A 4LFGA 5E8KA 3OYRA 5DHKA 3ACWA 2P1CA 5B00A 3CC9A 3P8RA 1VG2A 5A0JA 3B7LA 1V4JA 3M00A 3MAVA 3KROB 4Q23A 2Z50A 2ZCRA 4LLTA 4E9UA 3Q1OA 3OABB 4GAXA 5IM1A 4LZ3A 3CP6A 3P5PA 1EZFA 3NPKA 5DIQF 5DJPF 5ILDA 3PDEA 5IVGA 5DZ2A 2OA6A 3N6KF 3Q2ZA 3EZ3A 2F7MF 5ILJA 5E8LA 1WL2A 3ADZA 5A0KA 2FTZA 2I19A 2Z7IA 5AYPA 4KVWA 1VG6A 1HXAA 1N24A 5JV2F 3ICNA 2Z4VA 2AEKA 3ACXA 3WCLA 5B0MA 4RYPA 4LPGF 3LEEA 1VG4A 3V66A 5DJRF 5ERNA 5HN7A 2F8ZF 4DXJA 1WL0A 3P8LA 4JZXA 1UBXA 4LIXA 4KFAA 3QQVA 2E4OA 1HXGA 5B03A 2AELA 4F6VA 2ONGA 5IL8A 2J5CA 1VG3A 3QKCA 3LK5A 4LTVA 2PS4A 5EASA 2ONHA 3VJEA 3WE9A 5IN8A 4E9ZA 3N0GA 3AE0A 3WSAA 1V4IA 5B0LA 4H5DF 3BNYA 3NRIA 5ILHA 1YJ4A 5CG6A 3WEJA 4JVJF 5DHIA 3WCEA 2Z4YA 3Q2QA 4XQRF 4H5CF 3KRCA 4XQTF 3LJIA 3WEIA 3EFQA 3WJNA 3WCBA 2H8OA 3N3LF 3ICKA 3G4FA 3MZVA 2VF6A 3DYHA 4JYXA 4NKEA 5ILZA 3AQ0A 1YYTA 5DGMF 3WJOA 3S9VA 3W7FA 3IBAA 5I1UA 1HX9A 2ZCQA 2AETA 1N21A 3LDWA 3BNXA 2E8UA 4LLSA 4OKZA 1V4HA 3KB9A 4N1ZF 2RAHA 3DYGA 5B02A 2O1OA 2E90A 2OPMA 1KIZA 2F8CF 4DWBA 5IMIA 1YHMA 2Z4WA 4L2XF 4KPDA 3CKEA 3VJAA 2EWGA 2ZEVA 5AHUB 3WEFA 5H9DA 4LFVF 2E95A 4OKMA 3TFPA 3ZOUA 4KQSA 3LGZB 3M01A 3PH7A 5ILYA 1ZW5A 2F89F 4KPJA 3DYFA 3TFNA 5ER8A 3V1VA 3OACA 5HN8A 4RXEA 5HN9A 2F94F 3RMGA 5JV0F 3ACYA 3S4JA 1V4KA 1WKZA 3LGKA 1N22A 3KRAA 3N3DA 2F9KF 3KRFA 5IKAA 4KQ5A 3RYWA 1KIYA 1WL3A 4LFEA 4NFKF 2AZKA 5AFXA 2E93A 2OGDA 4F62A 3WCIA 3P41A 4N9UA 3KRPB 5IMNA 4LZCA 5ILIA 3N1VF 3KRCB 1YHLA 3WCMA 2E8TA 5HNAA 1YYRA 5DGSF 3SDRA 4LA5A 1HM4A 4KVDA 2Q58A 3N5HF 1FPSA 1YYQA 4LTZA 3EGTA 4WK5A 2E91A 3PKOA 2Z7HA 5IL3A 3WCHA 2Q9YA 4KK2A 2Z4XA 4K10A 3WSBA 2QISA 3SDQA 3P5RA 4OMGA 5EROA 2ZCSA 3N0FA 4UMJA 1DI1A 5IK6A 5DJVF 3WJKA 3N45F 4P0WA 4QPFA 4NG6A 4KWDA 1UBYA 4LUUA 4F6XA 3VJ9A 3VJCA 2ZY1A 4EA1A 4P0VA 4JXYA 5E8HA 3WCAA 3ICMA 5JA0F 4JZBA 4E1EA 2FORA 3ASXA 5JUZF 3SAEA 3VJBA 4NKFA 4LPHF 2Z4ZA 3V1XA 4DI5A 2PS6A 2PS7A 4HD1A 3WCDA 1VG7A 2F92F 4LOBA 4PVYF 3WEHA 1WL1A 3APZA 3KBKA 3LVSA 2Z78A 4JXNA 4KKMA 5EATA 5DGNF 3WCFA 2E94A 1DGPA 2Q80A 3N46F 1WY0A 1JFGA 4FJQA 1RQIA 3M0GA 4RNQA 4EA2A 3OACB 4PVXF 3LSNA 2Z52A 4H5EF 4NUAA 3VJ8A 3WEGA 4RXDA 1UBVA 3TC1A 2E8VA 3KRAB 2AZLA 3LMDA 3KRFB 2E92A 2J1OA 3WCGA 4DWGA 2E8XA 3KROA 4QXSF 3RBMA 1RTRA 3TS7A 5KSXF 2E8WA 4LZ0A 2ZEUA 3M02A 3UCAA 3WEKA 3IPIA 3NF2A 4DZWA 3OABA 1UBWA 3VJDA 5B0KA 3NPRA 4KVYA 4GP2A 3PYAA 3SDUA 1YHKA 3LOMA 4RXAA 3ZMCA 1RQJA 5CG5A 3LLWA 2ZCOA 1YYSA 2PS5A 2J1PA 1PS1A 4RXCA 1N20A 4KVIA 3WCCA 3RYEA 3N1WF 5C05A 5EAUA 5B0IA 4OGUA 3ZCDA 4GP1A 3Q30A 1HXCA 3ICZA 1YYUA 3LG5A 3N5JF 1JFAA 4KQUA 1YV5A 4MC8A 4OMHA 1V4EA 4GA3A 5A0IA 3LZ9A 4MC0A 3ZL6A 5IKHA 1WMWA 3PYBA 4NFIF
chains in the Genus database with same CATH superfamily
3AQBB 2AZJA 3KRPA 5IK0A 1YQ7A 4DHDA 1N1BA 5ILKA 5DW7A 3M9UA 4DEMF 3G4DA 2PS8A 4LXWA 4XQSF 5AELA 4MC3A 3ID0A 4KUXA 3WC9A 1N23A 4FP4A 4LA6A 4NFJF 5JV1F 4P0XA 3SDTA 5B0JA 2OPNA 1N1ZA 2DH4A 3N49F 3WCJA 3TFVA 4ZQ8A 3AQCB 5IK9A 5IMPA 3SDVA 3ZMBA 2Q9ZA 5B01A 5ERMA 4EA0A 1HM7A 4LFGA 5E8KA 3OYRA 5DHKA 3ACWA 2P1CA 5B00A 3CC9A 3P8RA 1VG2A 5A0JA 3B7LA 1V4JA 3M00A 3MAVA 3KROB 4Q23A 2Z50A 2ZCRA 4LLTA 4E9UA 3Q1OA 3OABB 4GAXA 5IM1A 4LZ3A 3CP6A 3P5PA 1EZFA 3NPKA 5DIQF 5DJPF 5ILDA 3PDEA 5IVGA 5DZ2A 2OA6A 3N6KF 3Q2ZA 3EZ3A 2F7MF 5ILJA 5E8LA 1WL2A 3ADZA 5A0KA 2FTZA 2I19A 2Z7IA 5AYPA 4KVWA 1VG6A 1HXAA 1N24A 5JV2F 3ICNA 2Z4VA 2AEKA 3ACXA 3WCLA 5B0MA 4RYPA 4LPGF 3LEEA 1VG4A 3V66A 5DJRF 5ERNA 5HN7A 2F8ZF 4DXJA 1WL0A 3P8LA 4JZXA 1UBXA 4LIXA 4KFAA 3QQVA 2E4OA 1HXGA 5B03A 2AELA 4F6VA 2ONGA 5IL8A 2J5CA 1VG3A 3QKCA 3LK5A 4LTVA 2PS4A 5EASA 2ONHA 3VJEA 3WE9A 5IN8A 4E9ZA 3N0GA 3AE0A 3WSAA 1V4IA 5B0LA 4H5DF 3BNYA 3NRIA 5ILHA 1YJ4A 5CG6A 3WEJA 4JVJF 5DHIA 3WCEA 2Z4YA 3Q2QA 4XQRF 4H5CF 3KRCA 4XQTF 3LJIA 3WEIA 3EFQA 3WJNA 3WCBA 2H8OA 3N3LF 3ICKA 3G4FA 3MZVA 2VF6A 3DYHA 4JYXA 4NKEA 5ILZA 3AQ0A 1YYTA 5DGMF 3WJOA 3S9VA 3W7FA 3IBAA 5I1UA 1HX9A 2ZCQA 2AETA 1N21A 3LDWA 3BNXA 2E8UA 4LLSA 4OKZA 1V4HA 3KB9A 4N1ZF 2RAHA 3DYGA 5B02A 2O1OA 2E90A 2OPMA 1KIZA 2F8CF 4DWBA 5IMIA 1YHMA 2Z4WA 4L2XF 4KPDA 3CKEA 3VJAA 2EWGA 2ZEVA 5AHUB 3WEFA 5H9DA 4LFVF 2E95A 4OKMA 3TFPA 3ZOUA 4KQSA 3LGZB 3M01A 3PH7A 5ILYA 1ZW5A 2F89F 4KPJA 3DYFA 3TFNA 5ER8A 3V1VA 3OACA 5HN8A 4RXEA 5HN9A 2F94F 3RMGA 5JV0F 3ACYA 3S4JA 1V4KA 1WKZA 3LGKA 1N22A 3KRAA 3N3DA 2F9KF 3KRFA 5IKAA 4KQ5A 3RYWA 1KIYA 1WL3A 4LFEA 4NFKF 2AZKA 5AFXA 2E93A 2OGDA 4F62A 3WCIA 3P41A 4N9UA 3KRPB 5IMNA 4LZCA 5ILIA 3N1VF 3KRCB 1YHLA 3WCMA 2E8TA 5HNAA 1YYRA 5DGSF 3SDRA 4LA5A 1HM4A 4KVDA 2Q58A 3N5HF 1FPSA 1YYQA 4LTZA 3EGTA 4WK5A 2E91A 3PKOA 2Z7HA 5IL3A 3WCHA 2Q9YA 4KK2A 2Z4XA 4K10A 3WSBA 2QISA 3SDQA 3P5RA 4OMGA 5EROA 2ZCSA 3N0FA 4UMJA 1DI1A 5IK6A 5DJVF 3WJKA 3N45F 4P0WA 4QPFA 4NG6A 4KWDA 1UBYA 4LUUA 4F6XA 3VJ9A 3VJCA 2ZY1A 4EA1A 4P0VA 4JXYA 5E8HA 3WCAA 3ICMA 5JA0F 4JZBA 4E1EA 2FORA 3ASXA 5JUZF 3SAEA 3VJBA 4NKFA 4LPHF 2Z4ZA 3V1XA 4DI5A 2PS6A 2PS7A 4HD1A 3WCDA 1VG7A 2F92F 4LOBA 4PVYF 3WEHA 1WL1A 3APZA 3KBKA 3LVSA 2Z78A 4JXNA 4KKMA 5EATA 5DGNF 3WCFA 2E94A 1DGPA 2Q80A 3N46F 1WY0A 1JFGA 4FJQA 1RQIA 3M0GA 4RNQA 4EA2A 3OACB 4PVXF 3LSNA 2Z52A 4H5EF 4NUAA 3VJ8A 3WEGA 4RXDA 1UBVA 3TC1A 2E8VA 3KRAB 2AZLA 3LMDA 3KRFB 2E92A 2J1OA 3WCGA 4DWGA 2E8XA 3KROA 4QXSF 3RBMA 1RTRA 3TS7A 5KSXF 2E8WA 4LZ0A 2ZEUA 3M02A 3UCAA 3WEKA 3IPIA 3NF2A 4DZWA 3OABA 1UBWA 3VJDA 5B0KA 3NPRA 4KVYA 4GP2A 3PYAA 3SDUA 1YHKA 3LOMA 4RXAA 3ZMCA 1RQJA 5CG5A 3LLWA 2ZCOA 1YYSA 2PS5A 2J1PA 1PS1A 4RXCA 1N20A 4KVIA 3WCCA 3RYEA 3N1WF 5C05A 5EAUA 5B0IA 4OGUA 3ZCDA 4GP1A 3Q30A 1HXCA 3ICZA 1YYUA 3LG5A 3N5JF 1JFAA 4KQUA 1YV5A 4MC8A 4OMHA 1V4EA 4GA3A 5A0IA 3LZ9A 4MC0A 3ZL6A 5IKHA 1WMWA 3PYBA 4NFIF
chains in the Genus database with same CATH topology
3AQBB 2AZJA 3KRPA 5IK0A 1YQ7A 4DHDA 1N1BA 5ILKA 5DW7A 3M9UA 4DEMF 3G4DA 2PS8A 4LXWA 4XQSF 5AELA 4MC3A 3ID0A 4KUXA 3WC9A 1N23A 4FP4A 4LA6A 4NFJF 5JV1F 4P0XA 3SDTA 5B0JA 2OPNA 1N1ZA 2DH4A 3N49F 3WCJA 3TFVA 4ZQ8A 3AQCB 5IK9A 5IMPA 3SDVA 3ZMBA 2Q9ZA 5B01A 5ERMA 4EA0A 1HM7A 4LFGA 5E8KA 3OYRA 5DHKA 3ACWA 2P1CA 5B00A 3CC9A 3P8RA 1VG2A 5A0JA 3B7LA 1V4JA 3M00A 3MAVA 3KROB 4Q23A 2Z50A 2ZCRA 4LLTA 4E9UA 3Q1OA 3OABB 4GAXA 5IM1A 4LZ3A 3CP6A 3P5PA 1EZFA 3NPKA 5DIQF 5DJPF 5ILDA 3PDEA 5IVGA 5DZ2A 2OA6A 3N6KF 3Q2ZA 3EZ3A 2F7MF 5ILJA 5E8LA 1WL2A 3ADZA 5A0KA 2FTZA 2I19A 2Z7IA 5AYPA 4KVWA 1VG6A 1HXAA 1N24A 5JV2F 3ICNA 2Z4VA 2AEKA 3ACXA 3WCLA 5B0MA 4RYPA 4LPGF 3LEEA 1VG4A 3V66A 5DJRF 5ERNA 5HN7A 2F8ZF 4DXJA 1WL0A 3P8LA 4JZXA 1UBXA 4LIXA 4KFAA 3QQVA 2E4OA 1HXGA 5B03A 2AELA 4F6VA 2ONGA 5IL8A 2J5CA 1VG3A 3QKCA 3LK5A 4LTVA 2PS4A 5EASA 2ONHA 3VJEA 3WE9A 5IN8A 4E9ZA 3N0GA 3AE0A 3WSAA 1V4IA 5B0LA 4H5DF 3BNYA 3NRIA 5ILHA 1YJ4A 5CG6A 3WEJA 4JVJF 5DHIA 3WCEA 2Z4YA 3Q2QA 4XQRF 4H5CF 3KRCA 4XQTF 3LJIA 3WEIA 3EFQA 3WJNA 3WCBA 2H8OA 3N3LF 3ICKA 3G4FA 3MZVA 2VF6A 3DYHA 4JYXA 4NKEA 5ILZA 3AQ0A 1YYTA 5DGMF 3WJOA 3S9VA 3W7FA 3IBAA 5I1UA 1HX9A 2ZCQA 2AETA 1N21A 3LDWA 3BNXA 2E8UA 4LLSA 4OKZA 1V4HA 3KB9A 4N1ZF 2RAHA 3DYGA 5B02A 2O1OA 2E90A 2OPMA 1KIZA 2F8CF 4DWBA 5IMIA 1YHMA 2Z4WA 4L2XF 4KPDA 3CKEA 3VJAA 2EWGA 2ZEVA 5AHUB 3WEFA 5H9DA 4LFVF 2E95A 4OKMA 3TFPA 3ZOUA 4KQSA 3LGZB 3M01A 3PH7A 5ILYA 1ZW5A 2F89F 4KPJA 3DYFA 3TFNA 5ER8A 3V1VA 3OACA 5HN8A 4RXEA 5HN9A 2F94F 3RMGA 5JV0F 3ACYA 3S4JA 1V4KA 1WKZA 3LGKA 1N22A 3KRAA 3N3DA 2F9KF 3KRFA 5IKAA 4KQ5A 3RYWA 1KIYA 1WL3A 4LFEA 4NFKF 2AZKA 5AFXA 2E93A 2OGDA 4F62A 3WCIA 3P41A 4N9UA 3KRPB 5IMNA 4LZCA 5ILIA 3N1VF 3KRCB 1YHLA 3WCMA 2E8TA 5HNAA 1YYRA 5DGSF 3SDRA 4LA5A 1HM4A 4KVDA 2Q58A 3N5HF 1FPSA 1YYQA 4LTZA 3EGTA 4WK5A 2E91A 3PKOA 2Z7HA 5IL3A 3WCHA 2Q9YA 4KK2A 2Z4XA 4K10A 3WSBA 2QISA 3SDQA 3P5RA 4OMGA 5EROA 2ZCSA 3N0FA 4UMJA 1DI1A 5IK6A 5DJVF 3WJKA 3N45F 4P0WA 4QPFA 4NG6A 4KWDA 1UBYA 4LUUA 4F6XA 3VJ9A 3VJCA 2ZY1A 4EA1A 4P0VA 4JXYA 5E8HA 3WCAA 3ICMA 5JA0F 4JZBA 4E1EA 2FORA 3ASXA 5JUZF 3SAEA 3VJBA 4NKFA 4LPHF 2Z4ZA 3V1XA 4DI5A 2PS6A 2PS7A 4HD1A 3WCDA 1VG7A 2F92F 4LOBA 4PVYF 3WEHA 1WL1A 3APZA 3KBKA 3LVSA 2Z78A 4JXNA 4KKMA 5EATA 5DGNF 3WCFA 2E94A 1DGPA 2Q80A 3N46F 1WY0A 1JFGA 4FJQA 1RQIA 3M0GA 4RNQA 4EA2A 3OACB 4PVXF 3LSNA 2Z52A 4H5EF 4NUAA 3VJ8A 3WEGA 4RXDA 1UBVA 3TC1A 2E8VA 3KRAB 2AZLA 3LMDA 3KRFB 2E92A 2J1OA 3WCGA 4DWGA 2E8XA 3KROA 4QXSF 3RBMA 1RTRA 3TS7A 5KSXF 2E8WA 4LZ0A 2ZEUA 3M02A 3UCAA 3WEKA 3IPIA 3NF2A 4DZWA 3OABA 1UBWA 3VJDA 5B0KA 3NPRA 4KVYA 4GP2A 3PYAA 3SDUA 1YHKA 3LOMA 4RXAA 3ZMCA 1RQJA 5CG5A 3LLWA 2ZCOA 1YYSA 2PS5A 2J1PA 1PS1A 4RXCA 1N20A 4KVIA 3WCCA 3RYEA 3N1WF 5C05A 5EAUA 5B0IA 4OGUA 3ZCDA 4GP1A 3Q30A 1HXCA 3ICZA 1YYUA 3LG5A 3N5JF 1JFAA 4KQUA 1YV5A 4MC8A 4OMHA 1V4EA 4GA3A 5A0IA 3LZ9A 4MC0A 3ZL6A 5IKHA 1WMWA 3PYBA 4NFIF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AQB B;  2AZJ A;  3KRP A;  5IK0 A;  1YQ7 A;  4DHD A;  1N1B A;  5ILK A;  5DW7 A;  3M9U A;  4DEM F;  3G4D A;  2PS8 A;  4LXW A;  4XQS F;  5AEL A;  4MC3 A;  3ID0 A;  4KUX A;  3WC9 A;  1N23 A;  4FP4 A;  4LA6 A;  4NFJ F;  5JV1 F;  4P0X A;  3SDT A;  5B0J A;  2OPN A;  1N1Z A;  2DH4 A;  3N49 F;  3WCJ A;  3TFV A;  4ZQ8 A;  3AQC B;  5IK9 A;  5IMP A;  3SDV A;  3ZMB A;  2Q9Z A;  5B01 A;  5ERM A;  4EA0 A;  1HM7 A;  4LFG A;  5E8K A;  3OYR A;  5DHK A;  3ACW A;  2P1C A;  5B00 A;  3CC9 A;  3P8R A;  1VG2 A;  5A0J A;  3B7L A;  1V4J A;  3M00 A;  3MAV A;  3KRO B;  4Q23 A;  2Z50 A;  2ZCR A;  4LLT A;  4E9U A;  3Q1O A;  3OAB B;  4GAX A;  5IM1 A;  4LZ3 A;  3CP6 A;  3P5P A;  1EZF A;  3NPK A;  5DIQ F;  5DJP F;  5ILD A;  3PDE A;  5IVG A;  5DZ2 A;  2OA6 A;  3N6K F;  3Q2Z A;  3EZ3 A;  2F7M F;  5ILJ A;  5E8L A;  1WL2 A;  3ADZ A;  5A0K A;  2FTZ A;  2I19 A;  2Z7I A;  5AYP A;  4KVW A;  1VG6 A;  1HXA A;  1N24 A;  5JV2 F;  3ICN A;  2Z4V A;  2AEK A;  3ACX A;  3WCL A;  5B0M A;  4RYP A;  4LPG F;  3LEE A;  1VG4 A;  3V66 A;  5DJR F;  5ERN A;  5HN7 A;  2F8Z F;  4DXJ A;  1WL0 A;  3P8L A;  4JZX A;  1UBX A;  4LIX A;  4KFA A;  3QQV A;  2E4O A;  1HXG A;  5B03 A;  2AEL A;  4F6V A;  2ONG A;  5IL8 A;  2J5C A;  1VG3 A;  3QKC A;  3LK5 A;  4LTV A;  2PS4 A;  5EAS A;  2ONH A;  3VJE A;  3WE9 A;  5IN8 A;  4E9Z A;  3N0G A;  3AE0 A;  3WSA A;  1V4I A;  5B0L A;  4H5D F;  3BNY A;  3NRI A;  5ILH A;  1YJ4 A;  5CG6 A;  3WEJ A;  4JVJ F;  5DHI A;  3WCE A;  2Z4Y A;  3Q2Q A;  4XQR F;  4H5C F;  3KRC A;  4XQT F;  3LJI A;  3WEI A;  3EFQ A;  3WJN A;  3WCB A;  2H8O A;  3N3L F;  3ICK A;  3G4F A;  3MZV A;  2VF6 A;  3DYH A;  4JYX A;  4NKE A;  5ILZ A;  3AQ0 A;  1YYT A;  5DGM F;  3WJO A;  3S9V A;  3W7F A;  3IBA A;  5I1U A;  1HX9 A;  2ZCQ A;  2AET A;  1N21 A;  3LDW A;  3BNX A;  2E8U A;  4LLS A;  4OKZ A;  1V4H A;  3KB9 A;  4N1Z F;  2RAH A;  3DYG A;  5B02 A;  2O1O A;  2E90 A;  2OPM A;  1KIZ A;  2F8C F;  4DWB A;  5IMI A;  1YHM A;  2Z4W A;  4L2X F;  4KPD A;  3CKE A;  3VJA A;  2EWG A;  2ZEV A;  5AHU B;  3WEF A;  5H9D A;  4LFV F;  2E95 A;  4OKM A;  3TFP A;  3ZOU A;  4KQS A;  3LGZ B;  3M01 A;  3PH7 A;  5ILY A;  1ZW5 A;  2F89 F;  4KPJ A;  3DYF A;  3TFN A;  5ER8 A;  3V1V A;  3OAC A;  5HN8 A;  4RXE A;  5HN9 A;  2F94 F;  3RMG A;  5JV0 F;  3ACY A;  3S4J A;  1V4K A;  1WKZ A;  3LGK A;  1N22 A;  3KRA A;  3N3D A;  2F9K F;  3KRF A;  5IKA A;  4KQ5 A;  3RYW A;  1KIY A;  1WL3 A;  4LFE A;  4NFK F;  2AZK A;  5AFX A;  2E93 A;  2OGD A;  4F62 A;  3WCI A;  3P41 A;  4N9U A;  3KRP B;  5IMN A;  4LZC A;  5ILI A;  3N1V F;  3KRC B;  1YHL A;  3WCM A;  2E8T A;  5HNA A;  1YYR A;  5DGS F;  3SDR A;  4LA5 A;  1HM4 A;  4KVD A;  2Q58 A;  3N5H F;  1FPS A;  1YYQ A;  4LTZ A;  3EGT A;  4WK5 A;  2E91 A;  3PKO A;  2Z7H A;  5IL3 A;  3WCH A;  2Q9Y A;  4KK2 A;  2Z4X A;  4K10 A;  3WSB A;  2QIS A;  3SDQ A;  3P5R A;  4OMG A;  5ERO A;  2ZCS A;  3N0F A;  4UMJ A;  1DI1 A;  5IK6 A;  5DJV F;  3WJK A;  3N45 F;  4P0W A;  4QPF A;  4NG6 A;  4KWD A;  1UBY A;  4LUU A;  4F6X A;  3VJ9 A;  3VJC A;  2ZY1 A;  4EA1 A;  4P0V A;  4JXY A;  5E8H A;  3WCA A;  3ICM A;  5JA0 F;  4JZB A;  4E1E A;  2FOR A;  3ASX A;  5JUZ F;  3SAE A;  3VJB A;  4NKF A;  4LPH F;  2Z4Z A;  3V1X A;  4DI5 A;  2PS6 A;  2PS7 A;  4HD1 A;  3WCD A;  1VG7 A;  2F92 F;  4LOB A;  4PVY F;  3WEH A;  1WL1 A;  3APZ A;  3KBK A;  3LVS A;  2Z78 A;  4JXN A;  4KKM A;  5EAT A;  5DGN F;  3WCF A;  2E94 A;  1DGP A;  2Q80 A;  3N46 F;  1WY0 A;  1JFG A;  4FJQ A;  1RQI A;  3M0G A;  4RNQ A;  4EA2 A;  3OAC B;  4PVX F;  3LSN A;  2Z52 A;  4H5E F;  4NUA A;  3VJ8 A;  3WEG A;  4RXD A;  1UBV A;  3TC1 A;  2E8V A;  3KRA B;  2AZL A;  3LMD A;  3KRF B;  2E92 A;  2J1O A;  3WCG A;  4DWG A;  2E8X A;  3KRO A;  4QXS F;  3RBM A;  1RTR A;  3TS7 A;  5KSX F;  2E8W A;  4LZ0 A;  2ZEU A;  3M02 A;  3UCA A;  3WEK A;  3IPI A;  3NF2 A;  4DZW A;  3OAB A;  1UBW A;  3VJD A;  5B0K A;  3NPR A;  4KVY A;  4GP2 A;  3PYA A;  3SDU A;  1YHK A;  3LOM A;  4RXA A;  3ZMC A;  1RQJ A;  5CG5 A;  3LLW A;  2ZCO A;  1YYS A;  2PS5 A;  2J1P A;  1PS1 A;  4RXC A;  1N20 A;  4KVI A;  3WCC A;  3RYE A;  3N1W F;  5C05 A;  5EAU A;  5B0I A;  4OGU A;  3ZCD A;  4GP1 A;  3Q30 A;  1HXC A;  3ICZ A;  1YYU A;  3LG5 A;  3N5J F;  1JFA A;  4KQU A;  1YV5 A;  4MC8 A;  4OMH A;  1V4E A;  4GA3 A;  5A0I A;  3LZ9 A;  4MC0 A;  3ZL6 A;  5IKH A;  1WMW A;  3PYB A;  4NFI F; 
#chains in the Genus database with same CATH topology
 3AQB B;  2AZJ A;  3KRP A;  5IK0 A;  1YQ7 A;  4DHD A;  1N1B A;  5ILK A;  5DW7 A;  3M9U A;  4DEM F;  3G4D A;  2PS8 A;  4LXW A;  4XQS F;  5AEL A;  4MC3 A;  3ID0 A;  4KUX A;  3WC9 A;  1N23 A;  4FP4 A;  4LA6 A;  4NFJ F;  5JV1 F;  4P0X A;  3SDT A;  5B0J A;  2OPN A;  1N1Z A;  2DH4 A;  3N49 F;  3WCJ A;  3TFV A;  4ZQ8 A;  3AQC B;  5IK9 A;  5IMP A;  3SDV A;  3ZMB A;  2Q9Z A;  5B01 A;  5ERM A;  4EA0 A;  1HM7 A;  4LFG A;  5E8K A;  3OYR A;  5DHK A;  3ACW A;  2P1C A;  5B00 A;  3CC9 A;  3P8R A;  1VG2 A;  5A0J A;  3B7L A;  1V4J A;  3M00 A;  3MAV A;  3KRO B;  4Q23 A;  2Z50 A;  2ZCR A;  4LLT A;  4E9U A;  3Q1O A;  3OAB B;  4GAX A;  5IM1 A;  4LZ3 A;  3CP6 A;  3P5P A;  1EZF A;  3NPK A;  5DIQ F;  5DJP F;  5ILD A;  3PDE A;  5IVG A;  5DZ2 A;  2OA6 A;  3N6K F;  3Q2Z A;  3EZ3 A;  2F7M F;  5ILJ A;  5E8L A;  1WL2 A;  3ADZ A;  5A0K A;  2FTZ A;  2I19 A;  2Z7I A;  5AYP A;  4KVW A;  1VG6 A;  1HXA A;  1N24 A;  5JV2 F;  3ICN A;  2Z4V A;  2AEK A;  3ACX A;  3WCL A;  5B0M A;  4RYP A;  4LPG F;  3LEE A;  1VG4 A;  3V66 A;  5DJR F;  5ERN A;  5HN7 A;  2F8Z F;  4DXJ A;  1WL0 A;  3P8L A;  4JZX A;  1UBX A;  4LIX A;  4KFA A;  3QQV A;  2E4O A;  1HXG A;  5B03 A;  2AEL A;  4F6V A;  2ONG A;  5IL8 A;  2J5C A;  1VG3 A;  3QKC A;  3LK5 A;  4LTV A;  2PS4 A;  5EAS A;  2ONH A;  3VJE A;  3WE9 A;  5IN8 A;  4E9Z A;  3N0G A;  3AE0 A;  3WSA A;  1V4I A;  5B0L A;  4H5D F;  3BNY A;  3NRI A;  5ILH A;  1YJ4 A;  5CG6 A;  3WEJ A;  4JVJ F;  5DHI A;  3WCE A;  2Z4Y A;  3Q2Q A;  4XQR F;  4H5C F;  3KRC A;  4XQT F;  3LJI A;  3WEI A;  3EFQ A;  3WJN A;  3WCB A;  2H8O A;  3N3L F;  3ICK A;  3G4F A;  3MZV A;  2VF6 A;  3DYH A;  4JYX A;  4NKE A;  5ILZ A;  3AQ0 A;  1YYT A;  5DGM F;  3WJO A;  3S9V A;  3W7F A;  3IBA A;  5I1U A;  1HX9 A;  2ZCQ A;  2AET A;  1N21 A;  3LDW A;  3BNX A;  2E8U A;  4LLS A;  4OKZ A;  1V4H A;  3KB9 A;  4N1Z F;  2RAH A;  3DYG A;  5B02 A;  2O1O A;  2E90 A;  2OPM A;  1KIZ A;  2F8C F;  4DWB A;  5IMI A;  1YHM A;  2Z4W A;  4L2X F;  4KPD A;  3CKE A;  3VJA A;  2EWG A;  2ZEV A;  5AHU B;  3WEF A;  5H9D A;  4LFV F;  2E95 A;  4OKM A;  3TFP A;  3ZOU A;  4KQS A;  3LGZ B;  3M01 A;  3PH7 A;  5ILY A;  1ZW5 A;  2F89 F;  4KPJ A;  3DYF A;  3TFN A;  5ER8 A;  3V1V A;  3OAC A;  5HN8 A;  4RXE A;  5HN9 A;  2F94 F;  3RMG A;  5JV0 F;  3ACY A;  3S4J A;  1V4K A;  1WKZ A;  3LGK A;  1N22 A;  3KRA A;  3N3D A;  2F9K F;  3KRF A;  5IKA A;  4KQ5 A;  3RYW A;  1KIY A;  1WL3 A;  4LFE A;  4NFK F;  2AZK A;  5AFX A;  2E93 A;  2OGD A;  4F62 A;  3WCI A;  3P41 A;  4N9U A;  3KRP B;  5IMN A;  4LZC A;  5ILI A;  3N1V F;  3KRC B;  1YHL A;  3WCM A;  2E8T A;  5HNA A;  1YYR A;  5DGS F;  3SDR A;  4LA5 A;  1HM4 A;  4KVD A;  2Q58 A;  3N5H F;  1FPS A;  1YYQ A;  4LTZ A;  3EGT A;  4WK5 A;  2E91 A;  3PKO A;  2Z7H A;  5IL3 A;  3WCH A;  2Q9Y A;  4KK2 A;  2Z4X A;  4K10 A;  3WSB A;  2QIS A;  3SDQ A;  3P5R A;  4OMG A;  5ERO A;  2ZCS A;  3N0F A;  4UMJ A;  1DI1 A;  5IK6 A;  5DJV F;  3WJK A;  3N45 F;  4P0W A;  4QPF A;  4NG6 A;  4KWD A;  1UBY A;  4LUU A;  4F6X A;  3VJ9 A;  3VJC A;  2ZY1 A;  4EA1 A;  4P0V A;  4JXY A;  5E8H A;  3WCA A;  3ICM A;  5JA0 F;  4JZB A;  4E1E A;  2FOR A;  3ASX A;  5JUZ F;  3SAE A;  3VJB A;  4NKF A;  4LPH F;  2Z4Z A;  3V1X A;  4DI5 A;  2PS6 A;  2PS7 A;  4HD1 A;  3WCD A;  1VG7 A;  2F92 F;  4LOB A;  4PVY F;  3WEH A;  1WL1 A;  3APZ A;  3KBK A;  3LVS A;  2Z78 A;  4JXN A;  4KKM A;  5EAT A;  5DGN F;  3WCF A;  2E94 A;  1DGP A;  2Q80 A;  3N46 F;  1WY0 A;  1JFG A;  4FJQ A;  1RQI A;  3M0G A;  4RNQ A;  4EA2 A;  3OAC B;  4PVX F;  3LSN A;  2Z52 A;  4H5E F;  4NUA A;  3VJ8 A;  3WEG A;  4RXD A;  1UBV A;  3TC1 A;  2E8V A;  3KRA B;  2AZL A;  3LMD A;  3KRF B;  2E92 A;  2J1O A;  3WCG A;  4DWG A;  2E8X A;  3KRO A;  4QXS F;  3RBM A;  1RTR A;  3TS7 A;  5KSX F;  2E8W A;  4LZ0 A;  2ZEU A;  3M02 A;  3UCA A;  3WEK A;  3IPI A;  3NF2 A;  4DZW A;  3OAB A;  1UBW A;  3VJD A;  5B0K A;  3NPR A;  4KVY A;  4GP2 A;  3PYA A;  3SDU A;  1YHK A;  3LOM A;  4RXA A;  3ZMC A;  1RQJ A;  5CG5 A;  3LLW A;  2ZCO A;  1YYS A;  2PS5 A;  2J1P A;  1PS1 A;  4RXC A;  1N20 A;  4KVI A;  3WCC A;  3RYE A;  3N1W F;  5C05 A;  5EAU A;  5B0I A;  4OGU A;  3ZCD A;  4GP1 A;  3Q30 A;  1HXC A;  3ICZ A;  1YYU A;  3LG5 A;  3N5J F;  1JFA A;  4KQU A;  1YV5 A;  4MC8 A;  4OMH A;  1V4E A;  4GA3 A;  5A0I A;  3LZ9 A;  4MC0 A;  3ZL6 A;  5IKH A;  1WMW A;  3PYB A;  4NFI F; 
#chains in the Genus database with same CATH homology
 3AQB B;  2AZJ A;  3KRP A;  5IK0 A;  1YQ7 A;  4DHD A;  1N1B A;  5ILK A;  5DW7 A;  3M9U A;  4DEM F;  3G4D A;  2PS8 A;  4LXW A;  4XQS F;  5AEL A;  4MC3 A;  3ID0 A;  4KUX A;  3WC9 A;  1N23 A;  4FP4 A;  4LA6 A;  4NFJ F;  5JV1 F;  4P0X A;  3SDT A;  5B0J A;  2OPN A;  1N1Z A;  2DH4 A;  3N49 F;  3WCJ A;  3TFV A;  4ZQ8 A;  3AQC B;  5IK9 A;  5IMP A;  3SDV A;  3ZMB A;  2Q9Z A;  5B01 A;  5ERM A;  4EA0 A;  1HM7 A;  4LFG A;  5E8K A;  3OYR A;  5DHK A;  3ACW A;  2P1C A;  5B00 A;  3CC9 A;  3P8R A;  1VG2 A;  5A0J A;  3B7L A;  1V4J A;  3M00 A;  3MAV A;  3KRO B;  4Q23 A;  2Z50 A;  2ZCR A;  4LLT A;  4E9U A;  3Q1O A;  3OAB B;  4GAX A;  5IM1 A;  4LZ3 A;  3CP6 A;  3P5P A;  1EZF A;  3NPK A;  5DIQ F;  5DJP F;  5ILD A;  3PDE A;  5IVG A;  5DZ2 A;  2OA6 A;  3N6K F;  3Q2Z A;  3EZ3 A;  2F7M F;  5ILJ A;  5E8L A;  1WL2 A;  3ADZ A;  5A0K A;  2FTZ A;  2I19 A;  2Z7I A;  5AYP A;  4KVW A;  1VG6 A;  1HXA A;  1N24 A;  5JV2 F;  3ICN A;  2Z4V A;  2AEK A;  3ACX A;  3WCL A;  5B0M A;  4RYP A;  4LPG F;  3LEE A;  1VG4 A;  3V66 A;  5DJR F;  5ERN A;  5HN7 A;  2F8Z F;  4DXJ A;  1WL0 A;  3P8L A;  4JZX A;  1UBX A;  4LIX A;  4KFA A;  3QQV A;  2E4O A;  1HXG A;  5B03 A;  2AEL A;  4F6V A;  2ONG A;  5IL8 A;  2J5C A;  1VG3 A;  3QKC A;  3LK5 A;  4LTV A;  2PS4 A;  5EAS A;  2ONH A;  3VJE A;  3WE9 A;  5IN8 A;  4E9Z A;  3N0G A;  3AE0 A;  3WSA A;  1V4I A;  5B0L A;  4H5D F;  3BNY A;  3NRI A;  5ILH A;  1YJ4 A;  5CG6 A;  3WEJ A;  4JVJ F;  5DHI A;  3WCE A;  2Z4Y A;  3Q2Q A;  4XQR F;  4H5C F;  3KRC A;  4XQT F;  3LJI A;  3WEI A;  3EFQ A;  3WJN A;  3WCB A;  2H8O A;  3N3L F;  3ICK A;  3G4F A;  3MZV A;  2VF6 A;  3DYH A;  4JYX A;  4NKE A;  5ILZ A;  3AQ0 A;  1YYT A;  5DGM F;  3WJO A;  3S9V A;  3W7F A;  3IBA A;  5I1U A;  1HX9 A;  2ZCQ A;  2AET A;  1N21 A;  3LDW A;  3BNX A;  2E8U A;  4LLS A;  4OKZ A;  1V4H A;  3KB9 A;  4N1Z F;  2RAH A;  3DYG A;  5B02 A;  2O1O A;  2E90 A;  2OPM A;  1KIZ A;  2F8C F;  4DWB A;  5IMI A;  1YHM A;  2Z4W A;  4L2X F;  4KPD A;  3CKE A;  3VJA A;  2EWG A;  2ZEV A;  5AHU B;  3WEF A;  5H9D A;  4LFV F;  2E95 A;  4OKM A;  3TFP A;  3ZOU A;  4KQS A;  3LGZ B;  3M01 A;  3PH7 A;  5ILY A;  1ZW5 A;  2F89 F;  4KPJ A;  3DYF A;  3TFN A;  5ER8 A;  3V1V A;  3OAC A;  5HN8 A;  4RXE A;  5HN9 A;  2F94 F;  3RMG A;  5JV0 F;  3ACY A;  3S4J A;  1V4K A;  1WKZ A;  3LGK A;  1N22 A;  3KRA A;  3N3D A;  2F9K F;  3KRF A;  5IKA A;  4KQ5 A;  3RYW A;  1KIY A;  1WL3 A;  4LFE A;  4NFK F;  2AZK A;  5AFX A;  2E93 A;  2OGD A;  4F62 A;  3WCI A;  3P41 A;  4N9U A;  3KRP B;  5IMN A;  4LZC A;  5ILI A;  3N1V F;  3KRC B;  1YHL A;  3WCM A;  2E8T A;  5HNA A;  1YYR A;  5DGS F;  3SDR A;  4LA5 A;  1HM4 A;  4KVD A;  2Q58 A;  3N5H F;  1FPS A;  1YYQ A;  4LTZ A;  3EGT A;  4WK5 A;  2E91 A;  3PKO A;  2Z7H A;  5IL3 A;  3WCH A;  2Q9Y A;  4KK2 A;  2Z4X A;  4K10 A;  3WSB A;  2QIS A;  3SDQ A;  3P5R A;  4OMG A;  5ERO A;  2ZCS A;  3N0F A;  4UMJ A;  1DI1 A;  5IK6 A;  5DJV F;  3WJK A;  3N45 F;  4P0W A;  4QPF A;  4NG6 A;  4KWD A;  1UBY A;  4LUU A;  4F6X A;  3VJ9 A;  3VJC A;  2ZY1 A;  4EA1 A;  4P0V A;  4JXY A;  5E8H A;  3WCA A;  3ICM A;  5JA0 F;  4JZB A;  4E1E A;  2FOR A;  3ASX A;  5JUZ F;  3SAE A;  3VJB A;  4NKF A;  4LPH F;  2Z4Z A;  3V1X A;  4DI5 A;  2PS6 A;  2PS7 A;  4HD1 A;  3WCD A;  1VG7 A;  2F92 F;  4LOB A;  4PVY F;  3WEH A;  1WL1 A;  3APZ A;  3KBK A;  3LVS A;  2Z78 A;  4JXN A;  4KKM A;  5EAT A;  5DGN F;  3WCF A;  2E94 A;  1DGP A;  2Q80 A;  3N46 F;  1WY0 A;  1JFG A;  4FJQ A;  1RQI A;  3M0G A;  4RNQ A;  4EA2 A;  3OAC B;  4PVX F;  3LSN A;  2Z52 A;  4H5E F;  4NUA A;  3VJ8 A;  3WEG A;  4RXD A;  1UBV A;  3TC1 A;  2E8V A;  3KRA B;  2AZL A;  3LMD A;  3KRF B;  2E92 A;  2J1O A;  3WCG A;  4DWG A;  2E8X A;  3KRO A;  4QXS F;  3RBM A;  1RTR A;  3TS7 A;  5KSX F;  2E8W A;  4LZ0 A;  2ZEU A;  3M02 A;  3UCA A;  3WEK A;  3IPI A;  3NF2 A;  4DZW A;  3OAB A;  1UBW A;  3VJD A;  5B0K A;  3NPR A;  4KVY A;  4GP2 A;  3PYA A;  3SDU A;  1YHK A;  3LOM A;  4RXA A;  3ZMC A;  1RQJ A;  5CG5 A;  3LLW A;  2ZCO A;  1YYS A;  2PS5 A;  2J1P A;  1PS1 A;  4RXC A;  1N20 A;  4KVI A;  3WCC A;  3RYE A;  3N1W F;  5C05 A;  5EAU A;  5B0I A;  4OGU A;  3ZCD A;  4GP1 A;  3Q30 A;  1HXC A;  3ICZ A;  1YYU A;  3LG5 A;  3N5J F;  1JFA A;  4KQU A;  1YV5 A;  4MC8 A;  4OMH A;  1V4E A;  4GA3 A;  5A0I A;  3LZ9 A;  4MC0 A;  3ZL6 A;  5IKH A;  1WMW A;  3PYB A;  4NFI F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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