4L2XF

Crystal structure of human fpps in complex with magnesium, cl02134, and inorganic pyrophosphate
Total Genus 146
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
146
sequence length
346
structure length
346
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
molecule keywords Farnesyl pyrophosphate synthase
publication title Thienopyrimidine Bisphosphonate (ThPBP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Optimization and Characterization of the Mode of Inhibition.
pubmed doi rcsb
source organism Homo sapiens
total genus 146
structure length 346
sequence length 346
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2013-06-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4l2xF00
4LZ3A 3P8RA 3WCLA 4LLTA 5ILYA 4OMGA 2E8UA 3KRFA 4RYPA 3KRPB 3Q2QA 3WEGA 3WCBA 3OACB 3WEKA 3TFVA 3KRAB 1HM7A 4DI5A 5ILZA 3WC9A 1HXAA 3RYWA 3SDRA 5B00A 1RQJA 1N23A 1EZFA 4KPJA 3LOMA 5DJPF 5HNAA 3VJDA 2ZY1A 3KROB 5E8KA 3WEIA 4KVDA 3WJOA 5AHUB 4KVYA 3NRIA 3N5HF 1PS1A 1WMWA 3DYFA 1YHMA 5A0KA 4LUUA 3ICZA 5C05A 4DEMF 5DGNF 4NG6A 3ZMBA 3WCAA 3AQ0A 3EFQA 4NFKF 3PYBA 5IMNA 4KKMA 2ZCRA 4KK2A 5DIQF 3WEFA 2ZCQA 3S4JA 1JFAA 3B7LA 3KRCA 3KRFB 5B0KA 3QKCA 3LEEA 3LK5A 5IK9A 4NUAA 3PKOA 1ZW5A 1YYTA 3KRPA 3VJ8A 3OACA 3LSNA 1RQIA 1VG7A 2AEKA 5IMIA 3KRAA 4LLSA 3ZL6A 3WCEA 3WCJA 4KWDA 3RYEA 4EA2A 3LVSA 4E1EA 2ZEUA 1V4IA 4H5DF 4WK5A 5HN8A 2F94F 3M9UA 5JA0F 3SDUA 4RXEA 3IPIA 3WCFA 1HM4A 4UMJA 4N1ZF 4LZCA 4ZQ8A 2ZCSA 3ADZA 4EA1A 1UBXA 3V66A 4PVXF 3G4FA 5JUZF 3WSAA 3ZMCA 4DWBA 4PVYF 5JV1F 3TFNA 3EGTA 3S9VA 2AZJA 3MAVA 3ZCDA 2AZLA 3IBAA 2J5CA 4RXCA 2Q9ZA 3G4DA 4KQUA 3DYGA 5AELA 3WJNA 1VG2A 2Q58A 3OABB 2E8TA 2F92F 2PS4A 3ACXA 1N24A 1N21A 1YHLA 3UCAA 3WSBA 1JFGA 2RAHA 4KPDA 1UBVA 1VG4A 4NFIF 3WCDA 3VJBA 4DZWA 4KQSA 5IVGA 3N5JF 3LGKA 3N3DA 5CG6A 4RNQA 4MC3A 3SAEA 5B02A 5ILJA 4RXDA 5DZ2A 1WL2A 4MC8A 3V1XA 1YV5A 4F6VA 4LZ0A 4GP1A 4LA5A 2Z7IA 2OGDA 3ZOUA 3N3LF 3VJAA 3CP6A 2PS7A 4H5CF 5ILDA 1YYQA 2F8CF 5B01A 2Q80A 1VG3A 3EZ3A 3AE0A 4OKMA 3TFPA 2E8VA 2AELA 3PYAA 2OA6A 4LTZA 2AZKA 1N22A 2Z4YA 4OMHA 4QXSF 5EASA 2I19A 5IM1A 5B03A 3OABA 2Z78A 4K10A 2DH4A 2F9KF 5DGMF 3LG5A 3LLWA 3SDVA 4LIXA 1UBWA 2ZCOA 1HXCA 1YQ7A 5ERMA 5I1UA 5B0IA 5DGSF 2QISA 4LXWA 5E8LA 5IL3A 5CG5A 2E95A 4NFJF 1VG6A 2J1PA 4P0WA 2PS8A 1YYUA 1DGPA 4DXJA 2Z50A 3VJCA 3CC9A 3ICMA 3V1VA 3M01A 3KBKA 1WL0A 3TS7A 4JXYA 1KIZA 3TC1A 3KB9A 2Z4XA 3ASXA 3NF2A 2AETA 1WL1A 3NPRA 3WE9A 4LFVF 1HXGA 1N20A 2E93A 3Q2ZA 2Z4VA 5B0MA 3LZ9A 4NKFA 3N46F 4XQSF 2ONHA 5IK0A 3BNXA 4KUXA 3WCGA 2Z4WA 3WJKA 3P41A 1UBYA 5E8HA 5DHIA 2E8WA 1YYRA 2E90A 3Q1OA 4QPFA 4GP2A 3PDEA 1HX9A 3ICKA 5IN8A 1YYSA 3NPKA 5IKHA 2OPNA 1V4KA 4JVJF 3WEJA 4RXAA 2F7MF 2OPMA 4KQ5A 4Q23A 4P0VA 3SDTA 4E9UA 4DWGA 1DI1A 4JYXA 3ACWA 4FP4A 3AQCB 4LFEA 5EATA 3ICNA 5IK6A 5IMPA 1V4JA 5ERNA 4H5EF 3W7FA 3VJEA 1WL3A 3BNYA 5A0JA 5AYPA 3M00A 4LFGA 4KFAA 3WCMA 5A0IA 5ILHA 2PS5A 5AFXA 2E94A 4GA3A 2E4OA 1N1BA 4OGUA 5H9DA 5ER8A 4P0XA 3WCHA 1V4HA 1WY0A 2E91A 5EAUA 3OYRA 2Z52A 2ONGA 1YHKA 2P1CA 2EWGA 2VF6A 4F62A 3M0GA 1V4EA 4LPHF 5JV0F 5EROA 3CKEA 4GAXA 3AQBB 3N6KF 2J1OA 4KVIA 4JZBA 1RTRA 5DW7A 2Z4ZA 3N49F 3N0GA 5IL8A 2E8XA 3RMGA 4JXNA 4OKZA 3M02A 2O1OA 3PH7A 3N0FA 3LJIA 3N1VF 1N1ZA 5KSXF 3LGZB 4FJQA 3ID0A 3WCIA 4JZXA 3SDQA 3LDWA 5B0LA 5DJVF 2ZEVA 4LA6A 5DHKA 5JV2F 3RBMA 4MC0A 3MZVA 3QQVA 5IKAA 3ACYA 4EA0A 3LMDA 4F6XA 1YJ4A 2Z7HA 2F8ZF 3DYHA 2FORA 3N1WF 4LTVA 3N45F 4NKEA 5HN9A 3P5RA 2E92A 3KROA 1WKZA 4L2XF 5ILIA 2PS6A 2Q9YA 1FPSA 3WCCA 4XQRF 3P8LA 5HN7A 4XQTF 5ILKA 3APZA 3P5PA 3WEHA 2FTZA 4DHDA 4N9UA 4LPGF 4LOBA 3Q30A 4HD1A 3VJ9A 4E9ZA 3KRCB 2F89F 4KVWA 5B0JA 5DJRF 2H8OA 1KIYA
chains in the Genus database with same CATH superfamily
4LZ3A 3P8RA 3WCLA 4LLTA 5ILYA 4OMGA 2E8UA 3KRFA 4RYPA 3KRPB 3Q2QA 3WEGA 3WCBA 3OACB 3WEKA 3TFVA 3KRAB 1HM7A 4DI5A 5ILZA 3WC9A 1HXAA 3RYWA 3SDRA 5B00A 1RQJA 1N23A 1EZFA 4KPJA 3LOMA 5DJPF 5HNAA 3VJDA 2ZY1A 3KROB 5E8KA 3WEIA 4KVDA 3WJOA 5AHUB 4KVYA 3NRIA 3N5HF 1PS1A 1WMWA 3DYFA 1YHMA 5A0KA 4LUUA 3ICZA 5C05A 4DEMF 5DGNF 4NG6A 3ZMBA 3WCAA 3AQ0A 3EFQA 4NFKF 3PYBA 5IMNA 4KKMA 2ZCRA 4KK2A 5DIQF 3WEFA 2ZCQA 3S4JA 1JFAA 3B7LA 3KRCA 3KRFB 5B0KA 3QKCA 3LEEA 3LK5A 5IK9A 4NUAA 3PKOA 1ZW5A 1YYTA 3KRPA 3VJ8A 3OACA 3LSNA 1RQIA 1VG7A 2AEKA 5IMIA 3KRAA 4LLSA 3ZL6A 3WCEA 3WCJA 4KWDA 3RYEA 4EA2A 3LVSA 4E1EA 2ZEUA 1V4IA 4H5DF 4WK5A 5HN8A 2F94F 3M9UA 5JA0F 3SDUA 4RXEA 3IPIA 3WCFA 1HM4A 4UMJA 4N1ZF 4LZCA 4ZQ8A 2ZCSA 3ADZA 4EA1A 1UBXA 3V66A 4PVXF 3G4FA 5JUZF 3WSAA 3ZMCA 4DWBA 4PVYF 5JV1F 3TFNA 3EGTA 3S9VA 2AZJA 3MAVA 3ZCDA 2AZLA 3IBAA 2J5CA 4RXCA 2Q9ZA 3G4DA 4KQUA 3DYGA 5AELA 3WJNA 1VG2A 2Q58A 3OABB 2E8TA 2F92F 2PS4A 3ACXA 1N24A 1N21A 1YHLA 3UCAA 3WSBA 1JFGA 2RAHA 4KPDA 1UBVA 1VG4A 4NFIF 3WCDA 3VJBA 4DZWA 4KQSA 5IVGA 3N5JF 3LGKA 3N3DA 5CG6A 4RNQA 4MC3A 3SAEA 5B02A 5ILJA 4RXDA 5DZ2A 1WL2A 4MC8A 3V1XA 1YV5A 4F6VA 4LZ0A 4GP1A 4LA5A 2Z7IA 2OGDA 3ZOUA 3N3LF 3VJAA 3CP6A 2PS7A 4H5CF 5ILDA 1YYQA 2F8CF 5B01A 2Q80A 1VG3A 3EZ3A 3AE0A 4OKMA 3TFPA 2E8VA 2AELA 3PYAA 2OA6A 4LTZA 2AZKA 1N22A 2Z4YA 4OMHA 4QXSF 5EASA 2I19A 5IM1A 5B03A 3OABA 2Z78A 4K10A 2DH4A 2F9KF 5DGMF 3LG5A 3LLWA 3SDVA 4LIXA 1UBWA 2ZCOA 1HXCA 1YQ7A 5ERMA 5I1UA 5B0IA 5DGSF 2QISA 4LXWA 5E8LA 5IL3A 5CG5A 2E95A 4NFJF 1VG6A 2J1PA 4P0WA 2PS8A 1YYUA 1DGPA 4DXJA 2Z50A 3VJCA 3CC9A 3ICMA 3V1VA 3M01A 3KBKA 1WL0A 3TS7A 4JXYA 1KIZA 3TC1A 3KB9A 2Z4XA 3ASXA 3NF2A 2AETA 1WL1A 3NPRA 3WE9A 4LFVF 1HXGA 1N20A 2E93A 3Q2ZA 2Z4VA 5B0MA 3LZ9A 4NKFA 3N46F 4XQSF 2ONHA 5IK0A 3BNXA 4KUXA 3WCGA 2Z4WA 3WJKA 3P41A 1UBYA 5E8HA 5DHIA 2E8WA 1YYRA 2E90A 3Q1OA 4QPFA 4GP2A 3PDEA 1HX9A 3ICKA 5IN8A 1YYSA 3NPKA 5IKHA 2OPNA 1V4KA 4JVJF 3WEJA 4RXAA 2F7MF 2OPMA 4KQ5A 4Q23A 4P0VA 3SDTA 4E9UA 4DWGA 1DI1A 4JYXA 3ACWA 4FP4A 3AQCB 4LFEA 5EATA 3ICNA 5IK6A 5IMPA 1V4JA 5ERNA 4H5EF 3W7FA 3VJEA 1WL3A 3BNYA 5A0JA 5AYPA 3M00A 4LFGA 4KFAA 3WCMA 5A0IA 5ILHA 2PS5A 5AFXA 2E94A 4GA3A 2E4OA 1N1BA 4OGUA 5H9DA 5ER8A 4P0XA 3WCHA 1V4HA 1WY0A 2E91A 5EAUA 3OYRA 2Z52A 2ONGA 1YHKA 2P1CA 2EWGA 2VF6A 4F62A 3M0GA 1V4EA 4LPHF 5JV0F 5EROA 3CKEA 4GAXA 3AQBB 3N6KF 2J1OA 4KVIA 4JZBA 1RTRA 5DW7A 2Z4ZA 3N49F 3N0GA 5IL8A 2E8XA 3RMGA 4JXNA 4OKZA 3M02A 2O1OA 3PH7A 3N0FA 3LJIA 3N1VF 1N1ZA 5KSXF 3LGZB 4FJQA 3ID0A 3WCIA 4JZXA 3SDQA 3LDWA 5B0LA 5DJVF 2ZEVA 4LA6A 5DHKA 5JV2F 3RBMA 4MC0A 3MZVA 3QQVA 5IKAA 3ACYA 4EA0A 3LMDA 4F6XA 1YJ4A 2Z7HA 2F8ZF 3DYHA 2FORA 3N1WF 4LTVA 3N45F 4NKEA 5HN9A 3P5RA 2E92A 3KROA 1WKZA 4L2XF 5ILIA 2PS6A 2Q9YA 1FPSA 3WCCA 4XQRF 3P8LA 5HN7A 4XQTF 5ILKA 3APZA 3P5PA 3WEHA 2FTZA 4DHDA 4N9UA 4LPGF 4LOBA 3Q30A 4HD1A 3VJ9A 4E9ZA 3KRCB 2F89F 4KVWA 5B0JA 5DJRF 2H8OA 1KIYA
chains in the Genus database with same CATH topology
4LZ3A 3P8RA 3WCLA 4LLTA 5ILYA 4OMGA 2E8UA 3KRFA 4RYPA 3KRPB 3Q2QA 3WEGA 3WCBA 3OACB 3WEKA 3TFVA 3KRAB 1HM7A 4DI5A 5ILZA 3WC9A 1HXAA 3RYWA 3SDRA 5B00A 1RQJA 1N23A 1EZFA 4KPJA 3LOMA 5DJPF 5HNAA 3VJDA 2ZY1A 3KROB 5E8KA 3WEIA 4KVDA 3WJOA 5AHUB 4KVYA 3NRIA 3N5HF 1PS1A 1WMWA 3DYFA 1YHMA 5A0KA 4LUUA 3ICZA 5C05A 4DEMF 5DGNF 4NG6A 3ZMBA 3WCAA 3AQ0A 3EFQA 4NFKF 3PYBA 5IMNA 4KKMA 2ZCRA 4KK2A 5DIQF 3WEFA 2ZCQA 3S4JA 1JFAA 3B7LA 3KRCA 3KRFB 5B0KA 3QKCA 3LEEA 3LK5A 5IK9A 4NUAA 3PKOA 1ZW5A 1YYTA 3KRPA 3VJ8A 3OACA 3LSNA 1RQIA 1VG7A 2AEKA 5IMIA 3KRAA 4LLSA 3ZL6A 3WCEA 3WCJA 4KWDA 3RYEA 4EA2A 3LVSA 4E1EA 2ZEUA 1V4IA 4H5DF 4WK5A 5HN8A 2F94F 3M9UA 5JA0F 3SDUA 4RXEA 3IPIA 3WCFA 1HM4A 4UMJA 4N1ZF 4LZCA 4ZQ8A 2ZCSA 3ADZA 4EA1A 1UBXA 3V66A 4PVXF 3G4FA 5JUZF 3WSAA 3ZMCA 4DWBA 4PVYF 5JV1F 3TFNA 3EGTA 3S9VA 2AZJA 3MAVA 3ZCDA 2AZLA 3IBAA 2J5CA 4RXCA 2Q9ZA 3G4DA 4KQUA 3DYGA 5AELA 3WJNA 1VG2A 2Q58A 3OABB 2E8TA 2F92F 2PS4A 3ACXA 1N24A 1N21A 1YHLA 3UCAA 3WSBA 1JFGA 2RAHA 4KPDA 1UBVA 1VG4A 4NFIF 3WCDA 3VJBA 4DZWA 4KQSA 5IVGA 3N5JF 3LGKA 3N3DA 5CG6A 4RNQA 4MC3A 3SAEA 5B02A 5ILJA 4RXDA 5DZ2A 1WL2A 4MC8A 3V1XA 1YV5A 4F6VA 4LZ0A 4GP1A 4LA5A 2Z7IA 2OGDA 3ZOUA 3N3LF 3VJAA 3CP6A 2PS7A 4H5CF 5ILDA 1YYQA 2F8CF 5B01A 2Q80A 1VG3A 3EZ3A 3AE0A 4OKMA 3TFPA 2E8VA 2AELA 3PYAA 2OA6A 4LTZA 2AZKA 1N22A 2Z4YA 4OMHA 4QXSF 5EASA 2I19A 5IM1A 5B03A 3OABA 2Z78A 4K10A 2DH4A 2F9KF 5DGMF 3LG5A 3LLWA 3SDVA 4LIXA 1UBWA 2ZCOA 1HXCA 1YQ7A 5ERMA 5I1UA 5B0IA 5DGSF 2QISA 4LXWA 5E8LA 5IL3A 5CG5A 2E95A 4NFJF 1VG6A 2J1PA 4P0WA 2PS8A 1YYUA 1DGPA 4DXJA 2Z50A 3VJCA 3CC9A 3ICMA 3V1VA 3M01A 3KBKA 1WL0A 3TS7A 4JXYA 1KIZA 3TC1A 3KB9A 2Z4XA 3ASXA 3NF2A 2AETA 1WL1A 3NPRA 3WE9A 4LFVF 1HXGA 1N20A 2E93A 3Q2ZA 2Z4VA 5B0MA 3LZ9A 4NKFA 3N46F 4XQSF 2ONHA 5IK0A 3BNXA 4KUXA 3WCGA 2Z4WA 3WJKA 3P41A 1UBYA 5E8HA 5DHIA 2E8WA 1YYRA 2E90A 3Q1OA 4QPFA 4GP2A 3PDEA 1HX9A 3ICKA 5IN8A 1YYSA 3NPKA 5IKHA 2OPNA 1V4KA 4JVJF 3WEJA 4RXAA 2F7MF 2OPMA 4KQ5A 4Q23A 4P0VA 3SDTA 4E9UA 4DWGA 1DI1A 4JYXA 3ACWA 4FP4A 3AQCB 4LFEA 5EATA 3ICNA 5IK6A 5IMPA 1V4JA 5ERNA 4H5EF 3W7FA 3VJEA 1WL3A 3BNYA 5A0JA 5AYPA 3M00A 4LFGA 4KFAA 3WCMA 5A0IA 5ILHA 2PS5A 5AFXA 2E94A 4GA3A 2E4OA 1N1BA 4OGUA 5H9DA 5ER8A 4P0XA 3WCHA 1V4HA 1WY0A 2E91A 5EAUA 3OYRA 2Z52A 2ONGA 1YHKA 2P1CA 2EWGA 2VF6A 4F62A 3M0GA 1V4EA 4LPHF 5JV0F 5EROA 3CKEA 4GAXA 3AQBB 3N6KF 2J1OA 4KVIA 4JZBA 1RTRA 5DW7A 2Z4ZA 3N49F 3N0GA 5IL8A 2E8XA 3RMGA 4JXNA 4OKZA 3M02A 2O1OA 3PH7A 3N0FA 3LJIA 3N1VF 1N1ZA 5KSXF 3LGZB 4FJQA 3ID0A 3WCIA 4JZXA 3SDQA 3LDWA 5B0LA 5DJVF 2ZEVA 4LA6A 5DHKA 5JV2F 3RBMA 4MC0A 3MZVA 3QQVA 5IKAA 3ACYA 4EA0A 3LMDA 4F6XA 1YJ4A 2Z7HA 2F8ZF 3DYHA 2FORA 3N1WF 4LTVA 3N45F 4NKEA 5HN9A 3P5RA 2E92A 3KROA 1WKZA 4L2XF 5ILIA 2PS6A 2Q9YA 1FPSA 3WCCA 4XQRF 3P8LA 5HN7A 4XQTF 5ILKA 3APZA 3P5PA 3WEHA 2FTZA 4DHDA 4N9UA 4LPGF 4LOBA 3Q30A 4HD1A 3VJ9A 4E9ZA 3KRCB 2F89F 4KVWA 5B0JA 5DJRF 2H8OA 1KIYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LZ3 A;  3P8R A;  3WCL A;  4LLT A;  5ILY A;  4OMG A;  2E8U A;  3KRF A;  4RYP A;  3KRP B;  3Q2Q A;  3WEG A;  3WCB A;  3OAC B;  3WEK A;  3TFV A;  3KRA B;  1HM7 A;  4DI5 A;  5ILZ A;  3WC9 A;  1HXA A;  3RYW A;  3SDR A;  5B00 A;  1RQJ A;  1N23 A;  1EZF A;  4KPJ A;  3LOM A;  5DJP F;  5HNA A;  3VJD A;  2ZY1 A;  3KRO B;  5E8K A;  3WEI A;  4KVD A;  3WJO A;  5AHU B;  4KVY A;  3NRI A;  3N5H F;  1PS1 A;  1WMW A;  3DYF A;  1YHM A;  5A0K A;  4LUU A;  3ICZ A;  5C05 A;  4DEM F;  5DGN F;  4NG6 A;  3ZMB A;  3WCA A;  3AQ0 A;  3EFQ A;  4NFK F;  3PYB A;  5IMN A;  4KKM A;  2ZCR A;  4KK2 A;  5DIQ F;  3WEF A;  2ZCQ A;  3S4J A;  1JFA A;  3B7L A;  3KRC A;  3KRF B;  5B0K A;  3QKC A;  3LEE A;  3LK5 A;  5IK9 A;  4NUA A;  3PKO A;  1ZW5 A;  1YYT A;  3KRP A;  3VJ8 A;  3OAC A;  3LSN A;  1RQI A;  1VG7 A;  2AEK A;  5IMI A;  3KRA A;  4LLS A;  3ZL6 A;  3WCE A;  3WCJ A;  4KWD A;  3RYE A;  4EA2 A;  3LVS A;  4E1E A;  2ZEU A;  1V4I A;  4H5D F;  4WK5 A;  5HN8 A;  2F94 F;  3M9U A;  5JA0 F;  3SDU A;  4RXE A;  3IPI A;  3WCF A;  1HM4 A;  4UMJ A;  4N1Z F;  4LZC A;  4ZQ8 A;  2ZCS A;  3ADZ A;  4EA1 A;  1UBX A;  3V66 A;  4PVX F;  3G4F A;  5JUZ F;  3WSA A;  3ZMC A;  4DWB A;  4PVY F;  5JV1 F;  3TFN A;  3EGT A;  3S9V A;  2AZJ A;  3MAV A;  3ZCD A;  2AZL A;  3IBA A;  2J5C A;  4RXC A;  2Q9Z A;  3G4D A;  4KQU A;  3DYG A;  5AEL A;  3WJN A;  1VG2 A;  2Q58 A;  3OAB B;  2E8T A;  2F92 F;  2PS4 A;  3ACX A;  1N24 A;  1N21 A;  1YHL A;  3UCA A;  3WSB A;  1JFG A;  2RAH A;  4KPD A;  1UBV A;  1VG4 A;  4NFI F;  3WCD A;  3VJB A;  4DZW A;  4KQS A;  5IVG A;  3N5J F;  3LGK A;  3N3D A;  5CG6 A;  4RNQ A;  4MC3 A;  3SAE A;  5B02 A;  5ILJ A;  4RXD A;  5DZ2 A;  1WL2 A;  4MC8 A;  3V1X A;  1YV5 A;  4F6V A;  4LZ0 A;  4GP1 A;  4LA5 A;  2Z7I A;  2OGD A;  3ZOU A;  3N3L F;  3VJA A;  3CP6 A;  2PS7 A;  4H5C F;  5ILD A;  1YYQ A;  2F8C F;  5B01 A;  2Q80 A;  1VG3 A;  3EZ3 A;  3AE0 A;  4OKM A;  3TFP A;  2E8V A;  2AEL A;  3PYA A;  2OA6 A;  4LTZ A;  2AZK A;  1N22 A;  2Z4Y A;  4OMH A;  4QXS F;  5EAS A;  2I19 A;  5IM1 A;  5B03 A;  3OAB A;  2Z78 A;  4K10 A;  2DH4 A;  2F9K F;  5DGM F;  3LG5 A;  3LLW A;  3SDV A;  4LIX A;  1UBW A;  2ZCO A;  1HXC A;  1YQ7 A;  5ERM A;  5I1U A;  5B0I A;  5DGS F;  2QIS A;  4LXW A;  5E8L A;  5IL3 A;  5CG5 A;  2E95 A;  4NFJ F;  1VG6 A;  2J1P A;  4P0W A;  2PS8 A;  1YYU A;  1DGP A;  4DXJ A;  2Z50 A;  3VJC A;  3CC9 A;  3ICM A;  3V1V A;  3M01 A;  3KBK A;  1WL0 A;  3TS7 A;  4JXY A;  1KIZ A;  3TC1 A;  3KB9 A;  2Z4X A;  3ASX A;  3NF2 A;  2AET A;  1WL1 A;  3NPR A;  3WE9 A;  4LFV F;  1HXG A;  1N20 A;  2E93 A;  3Q2Z A;  2Z4V A;  5B0M A;  3LZ9 A;  4NKF A;  3N46 F;  4XQS F;  2ONH A;  5IK0 A;  3BNX A;  4KUX A;  3WCG A;  2Z4W A;  3WJK A;  3P41 A;  1UBY A;  5E8H A;  5DHI A;  2E8W A;  1YYR A;  2E90 A;  3Q1O A;  4QPF A;  4GP2 A;  3PDE A;  1HX9 A;  3ICK A;  5IN8 A;  1YYS A;  3NPK A;  5IKH A;  2OPN A;  1V4K A;  4JVJ F;  3WEJ A;  4RXA A;  2F7M F;  2OPM A;  4KQ5 A;  4Q23 A;  4P0V A;  3SDT A;  4E9U A;  4DWG A;  1DI1 A;  4JYX A;  3ACW A;  4FP4 A;  3AQC B;  4LFE A;  5EAT A;  3ICN A;  5IK6 A;  5IMP A;  1V4J A;  5ERN A;  4H5E F;  3W7F A;  3VJE A;  1WL3 A;  3BNY A;  5A0J A;  5AYP A;  3M00 A;  4LFG A;  4KFA A;  3WCM A;  5A0I A;  5ILH A;  2PS5 A;  5AFX A;  2E94 A;  4GA3 A;  2E4O A;  1N1B A;  4OGU A;  5H9D A;  5ER8 A;  4P0X A;  3WCH A;  1V4H A;  1WY0 A;  2E91 A;  5EAU A;  3OYR A;  2Z52 A;  2ONG A;  1YHK A;  2P1C A;  2EWG A;  2VF6 A;  4F62 A;  3M0G A;  1V4E A;  4LPH F;  5JV0 F;  5ERO A;  3CKE A;  4GAX A;  3AQB B;  3N6K F;  2J1O A;  4KVI A;  4JZB A;  1RTR A;  5DW7 A;  2Z4Z A;  3N49 F;  3N0G A;  5IL8 A;  2E8X A;  3RMG A;  4JXN A;  4OKZ A;  3M02 A;  2O1O A;  3PH7 A;  3N0F A;  3LJI A;  3N1V F;  1N1Z A;  5KSX F;  3LGZ B;  4FJQ A;  3ID0 A;  3WCI A;  4JZX A;  3SDQ A;  3LDW A;  5B0L A;  5DJV F;  2ZEV A;  4LA6 A;  5DHK A;  5JV2 F;  3RBM A;  4MC0 A;  3MZV A;  3QQV A;  5IKA A;  3ACY A;  4EA0 A;  3LMD A;  4F6X A;  1YJ4 A;  2Z7H A;  2F8Z F;  3DYH A;  2FOR A;  3N1W F;  4LTV A;  3N45 F;  4NKE A;  5HN9 A;  3P5R A;  2E92 A;  3KRO A;  1WKZ A;  4L2X F;  5ILI A;  2PS6 A;  2Q9Y A;  1FPS A;  3WCC A;  4XQR F;  3P8L A;  5HN7 A;  4XQT F;  5ILK A;  3APZ A;  3P5P A;  3WEH A;  2FTZ A;  4DHD A;  4N9U A;  4LPG F;  4LOB A;  3Q30 A;  4HD1 A;  3VJ9 A;  4E9Z A;  3KRC B;  2F89 F;  4KVW A;  5B0J A;  5DJR F;  2H8O A;  1KIY A; 
#chains in the Genus database with same CATH topology
 4LZ3 A;  3P8R A;  3WCL A;  4LLT A;  5ILY A;  4OMG A;  2E8U A;  3KRF A;  4RYP A;  3KRP B;  3Q2Q A;  3WEG A;  3WCB A;  3OAC B;  3WEK A;  3TFV A;  3KRA B;  1HM7 A;  4DI5 A;  5ILZ A;  3WC9 A;  1HXA A;  3RYW A;  3SDR A;  5B00 A;  1RQJ A;  1N23 A;  1EZF A;  4KPJ A;  3LOM A;  5DJP F;  5HNA A;  3VJD A;  2ZY1 A;  3KRO B;  5E8K A;  3WEI A;  4KVD A;  3WJO A;  5AHU B;  4KVY A;  3NRI A;  3N5H F;  1PS1 A;  1WMW A;  3DYF A;  1YHM A;  5A0K A;  4LUU A;  3ICZ A;  5C05 A;  4DEM F;  5DGN F;  4NG6 A;  3ZMB A;  3WCA A;  3AQ0 A;  3EFQ A;  4NFK F;  3PYB A;  5IMN A;  4KKM A;  2ZCR A;  4KK2 A;  5DIQ F;  3WEF A;  2ZCQ A;  3S4J A;  1JFA A;  3B7L A;  3KRC A;  3KRF B;  5B0K A;  3QKC A;  3LEE A;  3LK5 A;  5IK9 A;  4NUA A;  3PKO A;  1ZW5 A;  1YYT A;  3KRP A;  3VJ8 A;  3OAC A;  3LSN A;  1RQI A;  1VG7 A;  2AEK A;  5IMI A;  3KRA A;  4LLS A;  3ZL6 A;  3WCE A;  3WCJ A;  4KWD A;  3RYE A;  4EA2 A;  3LVS A;  4E1E A;  2ZEU A;  1V4I A;  4H5D F;  4WK5 A;  5HN8 A;  2F94 F;  3M9U A;  5JA0 F;  3SDU A;  4RXE A;  3IPI A;  3WCF A;  1HM4 A;  4UMJ A;  4N1Z F;  4LZC A;  4ZQ8 A;  2ZCS A;  3ADZ A;  4EA1 A;  1UBX A;  3V66 A;  4PVX F;  3G4F A;  5JUZ F;  3WSA A;  3ZMC A;  4DWB A;  4PVY F;  5JV1 F;  3TFN A;  3EGT A;  3S9V A;  2AZJ A;  3MAV A;  3ZCD A;  2AZL A;  3IBA A;  2J5C A;  4RXC A;  2Q9Z A;  3G4D A;  4KQU A;  3DYG A;  5AEL A;  3WJN A;  1VG2 A;  2Q58 A;  3OAB B;  2E8T A;  2F92 F;  2PS4 A;  3ACX A;  1N24 A;  1N21 A;  1YHL A;  3UCA A;  3WSB A;  1JFG A;  2RAH A;  4KPD A;  1UBV A;  1VG4 A;  4NFI F;  3WCD A;  3VJB A;  4DZW A;  4KQS A;  5IVG A;  3N5J F;  3LGK A;  3N3D A;  5CG6 A;  4RNQ A;  4MC3 A;  3SAE A;  5B02 A;  5ILJ A;  4RXD A;  5DZ2 A;  1WL2 A;  4MC8 A;  3V1X A;  1YV5 A;  4F6V A;  4LZ0 A;  4GP1 A;  4LA5 A;  2Z7I A;  2OGD A;  3ZOU A;  3N3L F;  3VJA A;  3CP6 A;  2PS7 A;  4H5C F;  5ILD A;  1YYQ A;  2F8C F;  5B01 A;  2Q80 A;  1VG3 A;  3EZ3 A;  3AE0 A;  4OKM A;  3TFP A;  2E8V A;  2AEL A;  3PYA A;  2OA6 A;  4LTZ A;  2AZK A;  1N22 A;  2Z4Y A;  4OMH A;  4QXS F;  5EAS A;  2I19 A;  5IM1 A;  5B03 A;  3OAB A;  2Z78 A;  4K10 A;  2DH4 A;  2F9K F;  5DGM F;  3LG5 A;  3LLW A;  3SDV A;  4LIX A;  1UBW A;  2ZCO A;  1HXC A;  1YQ7 A;  5ERM A;  5I1U A;  5B0I A;  5DGS F;  2QIS A;  4LXW A;  5E8L A;  5IL3 A;  5CG5 A;  2E95 A;  4NFJ F;  1VG6 A;  2J1P A;  4P0W A;  2PS8 A;  1YYU A;  1DGP A;  4DXJ A;  2Z50 A;  3VJC A;  3CC9 A;  3ICM A;  3V1V A;  3M01 A;  3KBK A;  1WL0 A;  3TS7 A;  4JXY A;  1KIZ A;  3TC1 A;  3KB9 A;  2Z4X A;  3ASX A;  3NF2 A;  2AET A;  1WL1 A;  3NPR A;  3WE9 A;  4LFV F;  1HXG A;  1N20 A;  2E93 A;  3Q2Z A;  2Z4V A;  5B0M A;  3LZ9 A;  4NKF A;  3N46 F;  4XQS F;  2ONH A;  5IK0 A;  3BNX A;  4KUX A;  3WCG A;  2Z4W A;  3WJK A;  3P41 A;  1UBY A;  5E8H A;  5DHI A;  2E8W A;  1YYR A;  2E90 A;  3Q1O A;  4QPF A;  4GP2 A;  3PDE A;  1HX9 A;  3ICK A;  5IN8 A;  1YYS A;  3NPK A;  5IKH A;  2OPN A;  1V4K A;  4JVJ F;  3WEJ A;  4RXA A;  2F7M F;  2OPM A;  4KQ5 A;  4Q23 A;  4P0V A;  3SDT A;  4E9U A;  4DWG A;  1DI1 A;  4JYX A;  3ACW A;  4FP4 A;  3AQC B;  4LFE A;  5EAT A;  3ICN A;  5IK6 A;  5IMP A;  1V4J A;  5ERN A;  4H5E F;  3W7F A;  3VJE A;  1WL3 A;  3BNY A;  5A0J A;  5AYP A;  3M00 A;  4LFG A;  4KFA A;  3WCM A;  5A0I A;  5ILH A;  2PS5 A;  5AFX A;  2E94 A;  4GA3 A;  2E4O A;  1N1B A;  4OGU A;  5H9D A;  5ER8 A;  4P0X A;  3WCH A;  1V4H A;  1WY0 A;  2E91 A;  5EAU A;  3OYR A;  2Z52 A;  2ONG A;  1YHK A;  2P1C A;  2EWG A;  2VF6 A;  4F62 A;  3M0G A;  1V4E A;  4LPH F;  5JV0 F;  5ERO A;  3CKE A;  4GAX A;  3AQB B;  3N6K F;  2J1O A;  4KVI A;  4JZB A;  1RTR A;  5DW7 A;  2Z4Z A;  3N49 F;  3N0G A;  5IL8 A;  2E8X A;  3RMG A;  4JXN A;  4OKZ A;  3M02 A;  2O1O A;  3PH7 A;  3N0F A;  3LJI A;  3N1V F;  1N1Z A;  5KSX F;  3LGZ B;  4FJQ A;  3ID0 A;  3WCI A;  4JZX A;  3SDQ A;  3LDW A;  5B0L A;  5DJV F;  2ZEV A;  4LA6 A;  5DHK A;  5JV2 F;  3RBM A;  4MC0 A;  3MZV A;  3QQV A;  5IKA A;  3ACY A;  4EA0 A;  3LMD A;  4F6X A;  1YJ4 A;  2Z7H A;  2F8Z F;  3DYH A;  2FOR A;  3N1W F;  4LTV A;  3N45 F;  4NKE A;  5HN9 A;  3P5R A;  2E92 A;  3KRO A;  1WKZ A;  4L2X F;  5ILI A;  2PS6 A;  2Q9Y A;  1FPS A;  3WCC A;  4XQR F;  3P8L A;  5HN7 A;  4XQT F;  5ILK A;  3APZ A;  3P5P A;  3WEH A;  2FTZ A;  4DHD A;  4N9U A;  4LPG F;  4LOB A;  3Q30 A;  4HD1 A;  3VJ9 A;  4E9Z A;  3KRC B;  2F89 F;  4KVW A;  5B0J A;  5DJR F;  2H8O A;  1KIY A; 
#chains in the Genus database with same CATH homology
 4LZ3 A;  3P8R A;  3WCL A;  4LLT A;  5ILY A;  4OMG A;  2E8U A;  3KRF A;  4RYP A;  3KRP B;  3Q2Q A;  3WEG A;  3WCB A;  3OAC B;  3WEK A;  3TFV A;  3KRA B;  1HM7 A;  4DI5 A;  5ILZ A;  3WC9 A;  1HXA A;  3RYW A;  3SDR A;  5B00 A;  1RQJ A;  1N23 A;  1EZF A;  4KPJ A;  3LOM A;  5DJP F;  5HNA A;  3VJD A;  2ZY1 A;  3KRO B;  5E8K A;  3WEI A;  4KVD A;  3WJO A;  5AHU B;  4KVY A;  3NRI A;  3N5H F;  1PS1 A;  1WMW A;  3DYF A;  1YHM A;  5A0K A;  4LUU A;  3ICZ A;  5C05 A;  4DEM F;  5DGN F;  4NG6 A;  3ZMB A;  3WCA A;  3AQ0 A;  3EFQ A;  4NFK F;  3PYB A;  5IMN A;  4KKM A;  2ZCR A;  4KK2 A;  5DIQ F;  3WEF A;  2ZCQ A;  3S4J A;  1JFA A;  3B7L A;  3KRC A;  3KRF B;  5B0K A;  3QKC A;  3LEE A;  3LK5 A;  5IK9 A;  4NUA A;  3PKO A;  1ZW5 A;  1YYT A;  3KRP A;  3VJ8 A;  3OAC A;  3LSN A;  1RQI A;  1VG7 A;  2AEK A;  5IMI A;  3KRA A;  4LLS A;  3ZL6 A;  3WCE A;  3WCJ A;  4KWD A;  3RYE A;  4EA2 A;  3LVS A;  4E1E A;  2ZEU A;  1V4I A;  4H5D F;  4WK5 A;  5HN8 A;  2F94 F;  3M9U A;  5JA0 F;  3SDU A;  4RXE A;  3IPI A;  3WCF A;  1HM4 A;  4UMJ A;  4N1Z F;  4LZC A;  4ZQ8 A;  2ZCS A;  3ADZ A;  4EA1 A;  1UBX A;  3V66 A;  4PVX F;  3G4F A;  5JUZ F;  3WSA A;  3ZMC A;  4DWB A;  4PVY F;  5JV1 F;  3TFN A;  3EGT A;  3S9V A;  2AZJ A;  3MAV A;  3ZCD A;  2AZL A;  3IBA A;  2J5C A;  4RXC A;  2Q9Z A;  3G4D A;  4KQU A;  3DYG A;  5AEL A;  3WJN A;  1VG2 A;  2Q58 A;  3OAB B;  2E8T A;  2F92 F;  2PS4 A;  3ACX A;  1N24 A;  1N21 A;  1YHL A;  3UCA A;  3WSB A;  1JFG A;  2RAH A;  4KPD A;  1UBV A;  1VG4 A;  4NFI F;  3WCD A;  3VJB A;  4DZW A;  4KQS A;  5IVG A;  3N5J F;  3LGK A;  3N3D A;  5CG6 A;  4RNQ A;  4MC3 A;  3SAE A;  5B02 A;  5ILJ A;  4RXD A;  5DZ2 A;  1WL2 A;  4MC8 A;  3V1X A;  1YV5 A;  4F6V A;  4LZ0 A;  4GP1 A;  4LA5 A;  2Z7I A;  2OGD A;  3ZOU A;  3N3L F;  3VJA A;  3CP6 A;  2PS7 A;  4H5C F;  5ILD A;  1YYQ A;  2F8C F;  5B01 A;  2Q80 A;  1VG3 A;  3EZ3 A;  3AE0 A;  4OKM A;  3TFP A;  2E8V A;  2AEL A;  3PYA A;  2OA6 A;  4LTZ A;  2AZK A;  1N22 A;  2Z4Y A;  4OMH A;  4QXS F;  5EAS A;  2I19 A;  5IM1 A;  5B03 A;  3OAB A;  2Z78 A;  4K10 A;  2DH4 A;  2F9K F;  5DGM F;  3LG5 A;  3LLW A;  3SDV A;  4LIX A;  1UBW A;  2ZCO A;  1HXC A;  1YQ7 A;  5ERM A;  5I1U A;  5B0I A;  5DGS F;  2QIS A;  4LXW A;  5E8L A;  5IL3 A;  5CG5 A;  2E95 A;  4NFJ F;  1VG6 A;  2J1P A;  4P0W A;  2PS8 A;  1YYU A;  1DGP A;  4DXJ A;  2Z50 A;  3VJC A;  3CC9 A;  3ICM A;  3V1V A;  3M01 A;  3KBK A;  1WL0 A;  3TS7 A;  4JXY A;  1KIZ A;  3TC1 A;  3KB9 A;  2Z4X A;  3ASX A;  3NF2 A;  2AET A;  1WL1 A;  3NPR A;  3WE9 A;  4LFV F;  1HXG A;  1N20 A;  2E93 A;  3Q2Z A;  2Z4V A;  5B0M A;  3LZ9 A;  4NKF A;  3N46 F;  4XQS F;  2ONH A;  5IK0 A;  3BNX A;  4KUX A;  3WCG A;  2Z4W A;  3WJK A;  3P41 A;  1UBY A;  5E8H A;  5DHI A;  2E8W A;  1YYR A;  2E90 A;  3Q1O A;  4QPF A;  4GP2 A;  3PDE A;  1HX9 A;  3ICK A;  5IN8 A;  1YYS A;  3NPK A;  5IKH A;  2OPN A;  1V4K A;  4JVJ F;  3WEJ A;  4RXA A;  2F7M F;  2OPM A;  4KQ5 A;  4Q23 A;  4P0V A;  3SDT A;  4E9U A;  4DWG A;  1DI1 A;  4JYX A;  3ACW A;  4FP4 A;  3AQC B;  4LFE A;  5EAT A;  3ICN A;  5IK6 A;  5IMP A;  1V4J A;  5ERN A;  4H5E F;  3W7F A;  3VJE A;  1WL3 A;  3BNY A;  5A0J A;  5AYP A;  3M00 A;  4LFG A;  4KFA A;  3WCM A;  5A0I A;  5ILH A;  2PS5 A;  5AFX A;  2E94 A;  4GA3 A;  2E4O A;  1N1B A;  4OGU A;  5H9D A;  5ER8 A;  4P0X A;  3WCH A;  1V4H A;  1WY0 A;  2E91 A;  5EAU A;  3OYR A;  2Z52 A;  2ONG A;  1YHK A;  2P1C A;  2EWG A;  2VF6 A;  4F62 A;  3M0G A;  1V4E A;  4LPH F;  5JV0 F;  5ERO A;  3CKE A;  4GAX A;  3AQB B;  3N6K F;  2J1O A;  4KVI A;  4JZB A;  1RTR A;  5DW7 A;  2Z4Z A;  3N49 F;  3N0G A;  5IL8 A;  2E8X A;  3RMG A;  4JXN A;  4OKZ A;  3M02 A;  2O1O A;  3PH7 A;  3N0F A;  3LJI A;  3N1V F;  1N1Z A;  5KSX F;  3LGZ B;  4FJQ A;  3ID0 A;  3WCI A;  4JZX A;  3SDQ A;  3LDW A;  5B0L A;  5DJV F;  2ZEV A;  4LA6 A;  5DHK A;  5JV2 F;  3RBM A;  4MC0 A;  3MZV A;  3QQV A;  5IKA A;  3ACY A;  4EA0 A;  3LMD A;  4F6X A;  1YJ4 A;  2Z7H A;  2F8Z F;  3DYH A;  2FOR A;  3N1W F;  4LTV A;  3N45 F;  4NKE A;  5HN9 A;  3P5R A;  2E92 A;  3KRO A;  1WKZ A;  4L2X F;  5ILI A;  2PS6 A;  2Q9Y A;  1FPS A;  3WCC A;  4XQR F;  3P8L A;  5HN7 A;  4XQT F;  5ILK A;  3APZ A;  3P5P A;  3WEH A;  2FTZ A;  4DHD A;  4N9U A;  4LPG F;  4LOB A;  3Q30 A;  4HD1 A;  3VJ9 A;  4E9Z A;  3KRC B;  2F89 F;  4KVW A;  5B0J A;  5DJR F;  2H8O A;  1KIY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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