3WSAA

The tuberculosis drug sq109 inhibits trypanosoma cruzi cell proliferation and acts synergistically with posaconazole
Total Genus 124
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
124
sequence length
334
structure length
329
Chain Sequence
LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords Squalene synthase
publication title The Tuberculosis Drug SQ109 Inhibits Trypanosoma cruzi Cell Proliferation and acts Synergistically with Posaconazole
rcsb
source organism Homo sapiens
total genus 124
structure length 329
sequence length 334
chains with identical sequence B, C, D, E, F
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2014-03-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3wsaA00
3SDVA 1HM4A 2RAHA 4DI5A 5JV1F 4KFAA 3ICZA 3IPIA 5A0IA 5ERNA 3WCAA 3ASXA 3AQCB 3WEHA 2F7MF 4XQRF 2Z4YA 3WEGA 3M01A 4LFEA 3OACB 2J5CA 2OPNA 4MC8A 2E8TA 2I19A 3UCAA 2AELA 5B01A 4NFIF 3N1WF 2Z4VA 3N45F 1UBXA 5ERMA 4QPFA 3NF2A 2F8CF 3DYGA 1YV5A 3QKCA 3M00A 3W7FA 2H8OA 3EZ3A 4GP1A 3AE0A 4L2XF 5KSXF 3Q2QA 5E8LA 1V4IA 4DZWA 4DEMF 4LA5A 1YYTA 4F62A 4OGUA 3LSNA 3P8LA 4KWDA 5AHUB 3G4DA 3WCBA 3WSBA 5HNAA 5IM1A 4LTVA 2Z4WA 4KVIA 3WCGA 1KIYA 4LXWA 2E95A 3TS7A 3BNXA 1ZW5A 4LLSA 4N1ZF 3PYBA 3OACA 3QQVA 2E8VA 2Z4XA 3TFNA 1WL0A 3VJDA 3WEJA 4EA0A 5ILJA 3M9UA 2E8XA 2PS5A 1WKZA 2ZCQA 3LLWA 1N24A 1UBYA 2F8ZF 3WCIA 4JVJF 2ZCRA 3V1VA 3LJIA 4K10A 5B0IA 3LZ9A 3KBKA 5IK0A 4KQUA 4LLTA 3VJEA 3ICKA 5DGMF 1YJ4A 4LTZA 3ACWA 4HD1A 1DGPA 5EATA 1VG7A 1N20A 3TC1A 4NKEA 5B00A 5IL8A 5A0KA 1YYRA 3ACYA 4E9ZA 1FPSA 3P8RA 4RXAA 2Q9YA 1HXAA 2FORA 3WE9A 3WJKA 4RNQA 2ZCSA 4KVYA 4JYXA 3VJCA 3G4FA 4JXYA 1N21A 3ICMA 1UBVA 5IL3A 4PVXF 5DHKA 2ZY1A 3VJBA 5A0JA 5AELA 1HXGA 3B7LA 5ILYA 3CKEA 2E93A 4H5EF 4JZXA 2E92A 4FP4A 3WCHA 3WCJA 3WC9A 4KPJA 5DJRF 4OMGA 4EA1A 3WCMA 2Z7HA 1YHKA 3SDQA 4DXJA 3NPKA 1N1ZA 4GA3A 3P41A 2AETA 2E4OA 4LFGA 5DZ2A 5JV0F 5DW7A 1WMWA 3RYWA 4F6XA 4WK5A 4KKMA 3N5HF 1VG2A 2F94F 5CG5A 3OYRA 5AYPA 3IBAA 2Z4ZA 5IK9A 1WY0A 3ZMBA 4RXEA 2Z50A 4GP2A 4Q23A 4EA2A 5HN9A 1KIZA 5ILHA 2AZLA 2AEKA 3APZA 1YYSA 4NG6A 3CP6A 2F92F 1VG4A 2Q80A 3PKOA 2E94A 4LA6A 5DGSF 3ZMCA 3ADZA 3LOMA 4KQ5A 3VJ9A 1N23A 5IKHA 3V66A 5ILKA 3SDUA 5B0MA 4JZBA 2OGDA 1YYUA 3RBMA 5DGNF 3KB9A 2ZEVA 3N0FA 2Z52A 3AQBB 3WSAA 2Z78A 5DJVF 5IMIA 2ZEUA 4OMHA 3EFQA 2O1OA 5DIQF 4DWGA 4NUAA 2ONGA 2E8WA 4OKMA 3SDTA 3WCLA 5ILZA 5I1UA 2AZKA 3WJNA 3LK5A 3KRPB 4KVWA 2J1OA 3Q2ZA 3ACXA 4F6VA 5H9DA 5CG6A 2PS8A 3KROB 3DYHA 5JUZF 5DJPF 5ILDA 1PS1A 4H5DF 4LIXA 5EASA 3WEKA 3WJOA 5JV2F 4NKFA 2AZJA 3AQ0A 4LPGF 3TFPA 3M02A 1N22A 3LGKA 3RYEA 2ONHA 2ZCOA 1RQIA 2PS6A 4PVYF 3N3LF 4LFVF 3N3DA 2FTZA 3DYFA 2PS4A 1N1BA 2OPMA 3LG5A 4KQSA 1V4HA 2E8UA 2PS7A 3N1VF 5B02A 4GAXA 3RMGA 5AFXA 4LPHF 3ZCDA 4XQSF 3N6KF 3Q30A 1JFGA 2P1CA 3PH7A 3Q1OA 4N9UA 3VJ8A 5B0JA 3OABB 3KRPA 1WL2A 4MC3A 3VJAA 3S9VA 3MAVA 4RXDA 3NRIA 5E8HA 5C05A 1V4KA 3SDRA 1RQJA 3N49F 4MC0A 2J1PA 1V4EA 3PYAA 2VF6A 4KPDA 3ICNA 5EROA 4NFJF 3KROA 4E9UA 3KRAB 4P0WA 1YHLA 3KRFB 5ILIA 4KVDA 3KRCB 1YQ7A 3N46F 4JXNA 4NFKF 3WCEA 3WCCA 3LMDA 5B0LA 4FJQA 4H5CF 3M0GA 1RTRA 3WEIA 1EZFA 3EGTA 3TFVA 4KK2A 5EAUA 4P0VA 3ZOUA 4OKZA 4LUUA 5JA0F 5HN8A 4P0XA 5HN7A 5IMPA 4LZ3A 3PDEA 2F9KF 3WCFA 3WEFA 3OABA 2Z7IA 3CC9A 4LZCA 1VG6A 3LVSA 3N0GA 5DHIA 2DH4A 5B0KA 4LOBA 4RXCA 2F89F 2EWGA 2Q9ZA 2OA6A 1WL3A 4XQTF 1WL1A 3KRAA 4KUXA 4DWBA 1YHMA 3ZL6A 3WCDA 1HXCA 3KRFA 1YYQA 3KRCA 5IVGA 1DI1A 4LZ0A 3LDWA 1VG3A 1HM7A 4RYPA 5ER8A 5IKAA 1JFAA 3P5RA 3ID0A 3V1XA 1V4JA 1UBWA 4DHDA 5B03A 3MZVA 3SAEA 3S4JA 2Q58A 4E1EA 3P5PA 2E90A 4ZQ8A 1HX9A 3LEEA 5IK6A 2E91A 3BNYA 3NPRA 5E8KA 5IMNA 4QXSF 4UMJA 2QISA 3N5JF 3LGZB 5IN8A
chains in the Genus database with same CATH superfamily
3SDVA 1HM4A 2RAHA 4DI5A 5JV1F 4KFAA 3ICZA 3IPIA 5A0IA 5ERNA 3WCAA 3ASXA 3AQCB 3WEHA 2F7MF 4XQRF 2Z4YA 3WEGA 3M01A 4LFEA 3OACB 2J5CA 2OPNA 4MC8A 2E8TA 2I19A 3UCAA 2AELA 5B01A 4NFIF 3N1WF 2Z4VA 3N45F 1UBXA 5ERMA 4QPFA 3NF2A 2F8CF 3DYGA 1YV5A 3QKCA 3M00A 3W7FA 2H8OA 3EZ3A 4GP1A 3AE0A 4L2XF 5KSXF 3Q2QA 5E8LA 1V4IA 4DZWA 4DEMF 4LA5A 1YYTA 4F62A 4OGUA 3LSNA 3P8LA 4KWDA 5AHUB 3G4DA 3WCBA 3WSBA 5HNAA 5IM1A 4LTVA 2Z4WA 4KVIA 3WCGA 1KIYA 4LXWA 2E95A 3TS7A 3BNXA 1ZW5A 4LLSA 4N1ZF 3PYBA 3OACA 3QQVA 2E8VA 2Z4XA 3TFNA 1WL0A 3VJDA 3WEJA 4EA0A 5ILJA 3M9UA 2E8XA 2PS5A 1WKZA 2ZCQA 3LLWA 1N24A 1UBYA 2F8ZF 3WCIA 4JVJF 2ZCRA 3V1VA 3LJIA 4K10A 5B0IA 3LZ9A 3KBKA 5IK0A 4KQUA 4LLTA 3VJEA 3ICKA 5DGMF 1YJ4A 4LTZA 3ACWA 4HD1A 1DGPA 5EATA 1VG7A 1N20A 3TC1A 4NKEA 5B00A 5IL8A 5A0KA 1YYRA 3ACYA 4E9ZA 1FPSA 3P8RA 4RXAA 2Q9YA 1HXAA 2FORA 3WE9A 3WJKA 4RNQA 2ZCSA 4KVYA 4JYXA 3VJCA 3G4FA 4JXYA 1N21A 3ICMA 1UBVA 5IL3A 4PVXF 5DHKA 2ZY1A 3VJBA 5A0JA 5AELA 1HXGA 3B7LA 5ILYA 3CKEA 2E93A 4H5EF 4JZXA 2E92A 4FP4A 3WCHA 3WCJA 3WC9A 4KPJA 5DJRF 4OMGA 4EA1A 3WCMA 2Z7HA 1YHKA 3SDQA 4DXJA 3NPKA 1N1ZA 4GA3A 3P41A 2AETA 2E4OA 4LFGA 5DZ2A 5JV0F 5DW7A 1WMWA 3RYWA 4F6XA 4WK5A 4KKMA 3N5HF 1VG2A 2F94F 5CG5A 3OYRA 5AYPA 3IBAA 2Z4ZA 5IK9A 1WY0A 3ZMBA 4RXEA 2Z50A 4GP2A 4Q23A 4EA2A 5HN9A 1KIZA 5ILHA 2AZLA 2AEKA 3APZA 1YYSA 4NG6A 3CP6A 2F92F 1VG4A 2Q80A 3PKOA 2E94A 4LA6A 5DGSF 3ZMCA 3ADZA 3LOMA 4KQ5A 3VJ9A 1N23A 5IKHA 3V66A 5ILKA 3SDUA 5B0MA 4JZBA 2OGDA 1YYUA 3RBMA 5DGNF 3KB9A 2ZEVA 3N0FA 2Z52A 3AQBB 3WSAA 2Z78A 5DJVF 5IMIA 2ZEUA 4OMHA 3EFQA 2O1OA 5DIQF 4DWGA 4NUAA 2ONGA 2E8WA 4OKMA 3SDTA 3WCLA 5ILZA 5I1UA 2AZKA 3WJNA 3LK5A 3KRPB 4KVWA 2J1OA 3Q2ZA 3ACXA 4F6VA 5H9DA 5CG6A 2PS8A 3KROB 3DYHA 5JUZF 5DJPF 5ILDA 1PS1A 4H5DF 4LIXA 5EASA 3WEKA 3WJOA 5JV2F 4NKFA 2AZJA 3AQ0A 4LPGF 3TFPA 3M02A 1N22A 3LGKA 3RYEA 2ONHA 2ZCOA 1RQIA 2PS6A 4PVYF 3N3LF 4LFVF 3N3DA 2FTZA 3DYFA 2PS4A 1N1BA 2OPMA 3LG5A 4KQSA 1V4HA 2E8UA 2PS7A 3N1VF 5B02A 4GAXA 3RMGA 5AFXA 4LPHF 3ZCDA 4XQSF 3N6KF 3Q30A 1JFGA 2P1CA 3PH7A 3Q1OA 4N9UA 3VJ8A 5B0JA 3OABB 3KRPA 1WL2A 4MC3A 3VJAA 3S9VA 3MAVA 4RXDA 3NRIA 5E8HA 5C05A 1V4KA 3SDRA 1RQJA 3N49F 4MC0A 2J1PA 1V4EA 3PYAA 2VF6A 4KPDA 3ICNA 5EROA 4NFJF 3KROA 4E9UA 3KRAB 4P0WA 1YHLA 3KRFB 5ILIA 4KVDA 3KRCB 1YQ7A 3N46F 4JXNA 4NFKF 3WCEA 3WCCA 3LMDA 5B0LA 4FJQA 4H5CF 3M0GA 1RTRA 3WEIA 1EZFA 3EGTA 3TFVA 4KK2A 5EAUA 4P0VA 3ZOUA 4OKZA 4LUUA 5JA0F 5HN8A 4P0XA 5HN7A 5IMPA 4LZ3A 3PDEA 2F9KF 3WCFA 3WEFA 3OABA 2Z7IA 3CC9A 4LZCA 1VG6A 3LVSA 3N0GA 5DHIA 2DH4A 5B0KA 4LOBA 4RXCA 2F89F 2EWGA 2Q9ZA 2OA6A 1WL3A 4XQTF 1WL1A 3KRAA 4KUXA 4DWBA 1YHMA 3ZL6A 3WCDA 1HXCA 3KRFA 1YYQA 3KRCA 5IVGA 1DI1A 4LZ0A 3LDWA 1VG3A 1HM7A 4RYPA 5ER8A 5IKAA 1JFAA 3P5RA 3ID0A 3V1XA 1V4JA 1UBWA 4DHDA 5B03A 3MZVA 3SAEA 3S4JA 2Q58A 4E1EA 3P5PA 2E90A 4ZQ8A 1HX9A 3LEEA 5IK6A 2E91A 3BNYA 3NPRA 5E8KA 5IMNA 4QXSF 4UMJA 2QISA 3N5JF 3LGZB 5IN8A
chains in the Genus database with same CATH topology
3SDVA 1HM4A 2RAHA 4DI5A 5JV1F 4KFAA 3ICZA 3IPIA 5A0IA 5ERNA 3WCAA 3ASXA 3AQCB 3WEHA 2F7MF 4XQRF 2Z4YA 3WEGA 3M01A 4LFEA 3OACB 2J5CA 2OPNA 4MC8A 2E8TA 2I19A 3UCAA 2AELA 5B01A 4NFIF 3N1WF 2Z4VA 3N45F 1UBXA 5ERMA 4QPFA 3NF2A 2F8CF 3DYGA 1YV5A 3QKCA 3M00A 3W7FA 2H8OA 3EZ3A 4GP1A 3AE0A 4L2XF 5KSXF 3Q2QA 5E8LA 1V4IA 4DZWA 4DEMF 4LA5A 1YYTA 4F62A 4OGUA 3LSNA 3P8LA 4KWDA 5AHUB 3G4DA 3WCBA 3WSBA 5HNAA 5IM1A 4LTVA 2Z4WA 4KVIA 3WCGA 1KIYA 4LXWA 2E95A 3TS7A 3BNXA 1ZW5A 4LLSA 4N1ZF 3PYBA 3OACA 3QQVA 2E8VA 2Z4XA 3TFNA 1WL0A 3VJDA 3WEJA 4EA0A 5ILJA 3M9UA 2E8XA 2PS5A 1WKZA 2ZCQA 3LLWA 1N24A 1UBYA 2F8ZF 3WCIA 4JVJF 2ZCRA 3V1VA 3LJIA 4K10A 5B0IA 3LZ9A 3KBKA 5IK0A 4KQUA 4LLTA 3VJEA 3ICKA 5DGMF 1YJ4A 4LTZA 3ACWA 4HD1A 1DGPA 5EATA 1VG7A 1N20A 3TC1A 4NKEA 5B00A 5IL8A 5A0KA 1YYRA 3ACYA 4E9ZA 1FPSA 3P8RA 4RXAA 2Q9YA 1HXAA 2FORA 3WE9A 3WJKA 4RNQA 2ZCSA 4KVYA 4JYXA 3VJCA 3G4FA 4JXYA 1N21A 3ICMA 1UBVA 5IL3A 4PVXF 5DHKA 2ZY1A 3VJBA 5A0JA 5AELA 1HXGA 3B7LA 5ILYA 3CKEA 2E93A 4H5EF 4JZXA 2E92A 4FP4A 3WCHA 3WCJA 3WC9A 4KPJA 5DJRF 4OMGA 4EA1A 3WCMA 2Z7HA 1YHKA 3SDQA 4DXJA 3NPKA 1N1ZA 4GA3A 3P41A 2AETA 2E4OA 4LFGA 5DZ2A 5JV0F 5DW7A 1WMWA 3RYWA 4F6XA 4WK5A 4KKMA 3N5HF 1VG2A 2F94F 5CG5A 3OYRA 5AYPA 3IBAA 2Z4ZA 5IK9A 1WY0A 3ZMBA 4RXEA 2Z50A 4GP2A 4Q23A 4EA2A 5HN9A 1KIZA 5ILHA 2AZLA 2AEKA 3APZA 1YYSA 4NG6A 3CP6A 2F92F 1VG4A 2Q80A 3PKOA 2E94A 4LA6A 5DGSF 3ZMCA 3ADZA 3LOMA 4KQ5A 3VJ9A 1N23A 5IKHA 3V66A 5ILKA 3SDUA 5B0MA 4JZBA 2OGDA 1YYUA 3RBMA 5DGNF 3KB9A 2ZEVA 3N0FA 2Z52A 3AQBB 3WSAA 2Z78A 5DJVF 5IMIA 2ZEUA 4OMHA 3EFQA 2O1OA 5DIQF 4DWGA 4NUAA 2ONGA 2E8WA 4OKMA 3SDTA 3WCLA 5ILZA 5I1UA 2AZKA 3WJNA 3LK5A 3KRPB 4KVWA 2J1OA 3Q2ZA 3ACXA 4F6VA 5H9DA 5CG6A 2PS8A 3KROB 3DYHA 5JUZF 5DJPF 5ILDA 1PS1A 4H5DF 4LIXA 5EASA 3WEKA 3WJOA 5JV2F 4NKFA 2AZJA 3AQ0A 4LPGF 3TFPA 3M02A 1N22A 3LGKA 3RYEA 2ONHA 2ZCOA 1RQIA 2PS6A 4PVYF 3N3LF 4LFVF 3N3DA 2FTZA 3DYFA 2PS4A 1N1BA 2OPMA 3LG5A 4KQSA 1V4HA 2E8UA 2PS7A 3N1VF 5B02A 4GAXA 3RMGA 5AFXA 4LPHF 3ZCDA 4XQSF 3N6KF 3Q30A 1JFGA 2P1CA 3PH7A 3Q1OA 4N9UA 3VJ8A 5B0JA 3OABB 3KRPA 1WL2A 4MC3A 3VJAA 3S9VA 3MAVA 4RXDA 3NRIA 5E8HA 5C05A 1V4KA 3SDRA 1RQJA 3N49F 4MC0A 2J1PA 1V4EA 3PYAA 2VF6A 4KPDA 3ICNA 5EROA 4NFJF 3KROA 4E9UA 3KRAB 4P0WA 1YHLA 3KRFB 5ILIA 4KVDA 3KRCB 1YQ7A 3N46F 4JXNA 4NFKF 3WCEA 3WCCA 3LMDA 5B0LA 4FJQA 4H5CF 3M0GA 1RTRA 3WEIA 1EZFA 3EGTA 3TFVA 4KK2A 5EAUA 4P0VA 3ZOUA 4OKZA 4LUUA 5JA0F 5HN8A 4P0XA 5HN7A 5IMPA 4LZ3A 3PDEA 2F9KF 3WCFA 3WEFA 3OABA 2Z7IA 3CC9A 4LZCA 1VG6A 3LVSA 3N0GA 5DHIA 2DH4A 5B0KA 4LOBA 4RXCA 2F89F 2EWGA 2Q9ZA 2OA6A 1WL3A 4XQTF 1WL1A 3KRAA 4KUXA 4DWBA 1YHMA 3ZL6A 3WCDA 1HXCA 3KRFA 1YYQA 3KRCA 5IVGA 1DI1A 4LZ0A 3LDWA 1VG3A 1HM7A 4RYPA 5ER8A 5IKAA 1JFAA 3P5RA 3ID0A 3V1XA 1V4JA 1UBWA 4DHDA 5B03A 3MZVA 3SAEA 3S4JA 2Q58A 4E1EA 3P5PA 2E90A 4ZQ8A 1HX9A 3LEEA 5IK6A 2E91A 3BNYA 3NPRA 5E8KA 5IMNA 4QXSF 4UMJA 2QISA 3N5JF 3LGZB 5IN8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SDV A;  1HM4 A;  2RAH A;  4DI5 A;  5JV1 F;  4KFA A;  3ICZ A;  3IPI A;  5A0I A;  5ERN A;  3WCA A;  3ASX A;  3AQC B;  3WEH A;  2F7M F;  4XQR F;  2Z4Y A;  3WEG A;  3M01 A;  4LFE A;  3OAC B;  2J5C A;  2OPN A;  4MC8 A;  2E8T A;  2I19 A;  3UCA A;  2AEL A;  5B01 A;  4NFI F;  3N1W F;  2Z4V A;  3N45 F;  1UBX A;  5ERM A;  4QPF A;  3NF2 A;  2F8C F;  3DYG A;  1YV5 A;  3QKC A;  3M00 A;  3W7F A;  2H8O A;  3EZ3 A;  4GP1 A;  3AE0 A;  4L2X F;  5KSX F;  3Q2Q A;  5E8L A;  1V4I A;  4DZW A;  4DEM F;  4LA5 A;  1YYT A;  4F62 A;  4OGU A;  3LSN A;  3P8L A;  4KWD A;  5AHU B;  3G4D A;  3WCB A;  3WSB A;  5HNA A;  5IM1 A;  4LTV A;  2Z4W A;  4KVI A;  3WCG A;  1KIY A;  4LXW A;  2E95 A;  3TS7 A;  3BNX A;  1ZW5 A;  4LLS A;  4N1Z F;  3PYB A;  3OAC A;  3QQV A;  2E8V A;  2Z4X A;  3TFN A;  1WL0 A;  3VJD A;  3WEJ A;  4EA0 A;  5ILJ A;  3M9U A;  2E8X A;  2PS5 A;  1WKZ A;  2ZCQ A;  3LLW A;  1N24 A;  1UBY A;  2F8Z F;  3WCI A;  4JVJ F;  2ZCR A;  3V1V A;  3LJI A;  4K10 A;  5B0I A;  3LZ9 A;  3KBK A;  5IK0 A;  4KQU A;  4LLT A;  3VJE A;  3ICK A;  5DGM F;  1YJ4 A;  4LTZ A;  3ACW A;  4HD1 A;  1DGP A;  5EAT A;  1VG7 A;  1N20 A;  3TC1 A;  4NKE A;  5B00 A;  5IL8 A;  5A0K A;  1YYR A;  3ACY A;  4E9Z A;  1FPS A;  3P8R A;  4RXA A;  2Q9Y A;  1HXA A;  2FOR A;  3WE9 A;  3WJK A;  4RNQ A;  2ZCS A;  4KVY A;  4JYX A;  3VJC A;  3G4F A;  4JXY A;  1N21 A;  3ICM A;  1UBV A;  5IL3 A;  4PVX F;  5DHK A;  2ZY1 A;  3VJB A;  5A0J A;  5AEL A;  1HXG A;  3B7L A;  5ILY A;  3CKE A;  2E93 A;  4H5E F;  4JZX A;  2E92 A;  4FP4 A;  3WCH A;  3WCJ A;  3WC9 A;  4KPJ A;  5DJR F;  4OMG A;  4EA1 A;  3WCM A;  2Z7H A;  1YHK A;  3SDQ A;  4DXJ A;  3NPK A;  1N1Z A;  4GA3 A;  3P41 A;  2AET A;  2E4O A;  4LFG A;  5DZ2 A;  5JV0 F;  5DW7 A;  1WMW A;  3RYW A;  4F6X A;  4WK5 A;  4KKM A;  3N5H F;  1VG2 A;  2F94 F;  5CG5 A;  3OYR A;  5AYP A;  3IBA A;  2Z4Z A;  5IK9 A;  1WY0 A;  3ZMB A;  4RXE A;  2Z50 A;  4GP2 A;  4Q23 A;  4EA2 A;  5HN9 A;  1KIZ A;  5ILH A;  2AZL A;  2AEK A;  3APZ A;  1YYS A;  4NG6 A;  3CP6 A;  2F92 F;  1VG4 A;  2Q80 A;  3PKO A;  2E94 A;  4LA6 A;  5DGS F;  3ZMC A;  3ADZ A;  3LOM A;  4KQ5 A;  3VJ9 A;  1N23 A;  5IKH A;  3V66 A;  5ILK A;  3SDU A;  5B0M A;  4JZB A;  2OGD A;  1YYU A;  3RBM A;  5DGN F;  3KB9 A;  2ZEV A;  3N0F A;  2Z52 A;  3AQB B;  3WSA A;  2Z78 A;  5DJV F;  5IMI A;  2ZEU A;  4OMH A;  3EFQ A;  2O1O A;  5DIQ F;  4DWG A;  4NUA A;  2ONG A;  2E8W A;  4OKM A;  3SDT A;  3WCL A;  5ILZ A;  5I1U A;  2AZK A;  3WJN A;  3LK5 A;  3KRP B;  4KVW A;  2J1O A;  3Q2Z A;  3ACX A;  4F6V A;  5H9D A;  5CG6 A;  2PS8 A;  3KRO B;  3DYH A;  5JUZ F;  5DJP F;  5ILD A;  1PS1 A;  4H5D F;  4LIX A;  5EAS A;  3WEK A;  3WJO A;  5JV2 F;  4NKF A;  2AZJ A;  3AQ0 A;  4LPG F;  3TFP A;  3M02 A;  1N22 A;  3LGK A;  3RYE A;  2ONH A;  2ZCO A;  1RQI A;  2PS6 A;  4PVY F;  3N3L F;  4LFV F;  3N3D A;  2FTZ A;  3DYF A;  2PS4 A;  1N1B A;  2OPM A;  3LG5 A;  4KQS A;  1V4H A;  2E8U A;  2PS7 A;  3N1V F;  5B02 A;  4GAX A;  3RMG A;  5AFX A;  4LPH F;  3ZCD A;  4XQS F;  3N6K F;  3Q30 A;  1JFG A;  2P1C A;  3PH7 A;  3Q1O A;  4N9U A;  3VJ8 A;  5B0J A;  3OAB B;  3KRP A;  1WL2 A;  4MC3 A;  3VJA A;  3S9V A;  3MAV A;  4RXD A;  3NRI A;  5E8H A;  5C05 A;  1V4K A;  3SDR A;  1RQJ A;  3N49 F;  4MC0 A;  2J1P A;  1V4E A;  3PYA A;  2VF6 A;  4KPD A;  3ICN A;  5ERO A;  4NFJ F;  3KRO A;  4E9U A;  3KRA B;  4P0W A;  1YHL A;  3KRF B;  5ILI A;  4KVD A;  3KRC B;  1YQ7 A;  3N46 F;  4JXN A;  4NFK F;  3WCE A;  3WCC A;  3LMD A;  5B0L A;  4FJQ A;  4H5C F;  3M0G A;  1RTR A;  3WEI A;  1EZF A;  3EGT A;  3TFV A;  4KK2 A;  5EAU A;  4P0V A;  3ZOU A;  4OKZ A;  4LUU A;  5JA0 F;  5HN8 A;  4P0X A;  5HN7 A;  5IMP A;  4LZ3 A;  3PDE A;  2F9K F;  3WCF A;  3WEF A;  3OAB A;  2Z7I A;  3CC9 A;  4LZC A;  1VG6 A;  3LVS A;  3N0G A;  5DHI A;  2DH4 A;  5B0K A;  4LOB A;  4RXC A;  2F89 F;  2EWG A;  2Q9Z A;  2OA6 A;  1WL3 A;  4XQT F;  1WL1 A;  3KRA A;  4KUX A;  4DWB A;  1YHM A;  3ZL6 A;  3WCD A;  1HXC A;  3KRF A;  1YYQ A;  3KRC A;  5IVG A;  1DI1 A;  4LZ0 A;  3LDW A;  1VG3 A;  1HM7 A;  4RYP A;  5ER8 A;  5IKA A;  1JFA A;  3P5R A;  3ID0 A;  3V1X A;  1V4J A;  1UBW A;  4DHD A;  5B03 A;  3MZV A;  3SAE A;  3S4J A;  2Q58 A;  4E1E A;  3P5P A;  2E90 A;  4ZQ8 A;  1HX9 A;  3LEE A;  5IK6 A;  2E91 A;  3BNY A;  3NPR A;  5E8K A;  5IMN A;  4QXS F;  4UMJ A;  2QIS A;  3N5J F;  3LGZ B;  5IN8 A; 
#chains in the Genus database with same CATH topology
 3SDV A;  1HM4 A;  2RAH A;  4DI5 A;  5JV1 F;  4KFA A;  3ICZ A;  3IPI A;  5A0I A;  5ERN A;  3WCA A;  3ASX A;  3AQC B;  3WEH A;  2F7M F;  4XQR F;  2Z4Y A;  3WEG A;  3M01 A;  4LFE A;  3OAC B;  2J5C A;  2OPN A;  4MC8 A;  2E8T A;  2I19 A;  3UCA A;  2AEL A;  5B01 A;  4NFI F;  3N1W F;  2Z4V A;  3N45 F;  1UBX A;  5ERM A;  4QPF A;  3NF2 A;  2F8C F;  3DYG A;  1YV5 A;  3QKC A;  3M00 A;  3W7F A;  2H8O A;  3EZ3 A;  4GP1 A;  3AE0 A;  4L2X F;  5KSX F;  3Q2Q A;  5E8L A;  1V4I A;  4DZW A;  4DEM F;  4LA5 A;  1YYT A;  4F62 A;  4OGU A;  3LSN A;  3P8L A;  4KWD A;  5AHU B;  3G4D A;  3WCB A;  3WSB A;  5HNA A;  5IM1 A;  4LTV A;  2Z4W A;  4KVI A;  3WCG A;  1KIY A;  4LXW A;  2E95 A;  3TS7 A;  3BNX A;  1ZW5 A;  4LLS A;  4N1Z F;  3PYB A;  3OAC A;  3QQV A;  2E8V A;  2Z4X A;  3TFN A;  1WL0 A;  3VJD A;  3WEJ A;  4EA0 A;  5ILJ A;  3M9U A;  2E8X A;  2PS5 A;  1WKZ A;  2ZCQ A;  3LLW A;  1N24 A;  1UBY A;  2F8Z F;  3WCI A;  4JVJ F;  2ZCR A;  3V1V A;  3LJI A;  4K10 A;  5B0I A;  3LZ9 A;  3KBK A;  5IK0 A;  4KQU A;  4LLT A;  3VJE A;  3ICK A;  5DGM F;  1YJ4 A;  4LTZ A;  3ACW A;  4HD1 A;  1DGP A;  5EAT A;  1VG7 A;  1N20 A;  3TC1 A;  4NKE A;  5B00 A;  5IL8 A;  5A0K A;  1YYR A;  3ACY A;  4E9Z A;  1FPS A;  3P8R A;  4RXA A;  2Q9Y A;  1HXA A;  2FOR A;  3WE9 A;  3WJK A;  4RNQ A;  2ZCS A;  4KVY A;  4JYX A;  3VJC A;  3G4F A;  4JXY A;  1N21 A;  3ICM A;  1UBV A;  5IL3 A;  4PVX F;  5DHK A;  2ZY1 A;  3VJB A;  5A0J A;  5AEL A;  1HXG A;  3B7L A;  5ILY A;  3CKE A;  2E93 A;  4H5E F;  4JZX A;  2E92 A;  4FP4 A;  3WCH A;  3WCJ A;  3WC9 A;  4KPJ A;  5DJR F;  4OMG A;  4EA1 A;  3WCM A;  2Z7H A;  1YHK A;  3SDQ A;  4DXJ A;  3NPK A;  1N1Z A;  4GA3 A;  3P41 A;  2AET A;  2E4O A;  4LFG A;  5DZ2 A;  5JV0 F;  5DW7 A;  1WMW A;  3RYW A;  4F6X A;  4WK5 A;  4KKM A;  3N5H F;  1VG2 A;  2F94 F;  5CG5 A;  3OYR A;  5AYP A;  3IBA A;  2Z4Z A;  5IK9 A;  1WY0 A;  3ZMB A;  4RXE A;  2Z50 A;  4GP2 A;  4Q23 A;  4EA2 A;  5HN9 A;  1KIZ A;  5ILH A;  2AZL A;  2AEK A;  3APZ A;  1YYS A;  4NG6 A;  3CP6 A;  2F92 F;  1VG4 A;  2Q80 A;  3PKO A;  2E94 A;  4LA6 A;  5DGS F;  3ZMC A;  3ADZ A;  3LOM A;  4KQ5 A;  3VJ9 A;  1N23 A;  5IKH A;  3V66 A;  5ILK A;  3SDU A;  5B0M A;  4JZB A;  2OGD A;  1YYU A;  3RBM A;  5DGN F;  3KB9 A;  2ZEV A;  3N0F A;  2Z52 A;  3AQB B;  3WSA A;  2Z78 A;  5DJV F;  5IMI A;  2ZEU A;  4OMH A;  3EFQ A;  2O1O A;  5DIQ F;  4DWG A;  4NUA A;  2ONG A;  2E8W A;  4OKM A;  3SDT A;  3WCL A;  5ILZ A;  5I1U A;  2AZK A;  3WJN A;  3LK5 A;  3KRP B;  4KVW A;  2J1O A;  3Q2Z A;  3ACX A;  4F6V A;  5H9D A;  5CG6 A;  2PS8 A;  3KRO B;  3DYH A;  5JUZ F;  5DJP F;  5ILD A;  1PS1 A;  4H5D F;  4LIX A;  5EAS A;  3WEK A;  3WJO A;  5JV2 F;  4NKF A;  2AZJ A;  3AQ0 A;  4LPG F;  3TFP A;  3M02 A;  1N22 A;  3LGK A;  3RYE A;  2ONH A;  2ZCO A;  1RQI A;  2PS6 A;  4PVY F;  3N3L F;  4LFV F;  3N3D A;  2FTZ A;  3DYF A;  2PS4 A;  1N1B A;  2OPM A;  3LG5 A;  4KQS A;  1V4H A;  2E8U A;  2PS7 A;  3N1V F;  5B02 A;  4GAX A;  3RMG A;  5AFX A;  4LPH F;  3ZCD A;  4XQS F;  3N6K F;  3Q30 A;  1JFG A;  2P1C A;  3PH7 A;  3Q1O A;  4N9U A;  3VJ8 A;  5B0J A;  3OAB B;  3KRP A;  1WL2 A;  4MC3 A;  3VJA A;  3S9V A;  3MAV A;  4RXD A;  3NRI A;  5E8H A;  5C05 A;  1V4K A;  3SDR A;  1RQJ A;  3N49 F;  4MC0 A;  2J1P A;  1V4E A;  3PYA A;  2VF6 A;  4KPD A;  3ICN A;  5ERO A;  4NFJ F;  3KRO A;  4E9U A;  3KRA B;  4P0W A;  1YHL A;  3KRF B;  5ILI A;  4KVD A;  3KRC B;  1YQ7 A;  3N46 F;  4JXN A;  4NFK F;  3WCE A;  3WCC A;  3LMD A;  5B0L A;  4FJQ A;  4H5C F;  3M0G A;  1RTR A;  3WEI A;  1EZF A;  3EGT A;  3TFV A;  4KK2 A;  5EAU A;  4P0V A;  3ZOU A;  4OKZ A;  4LUU A;  5JA0 F;  5HN8 A;  4P0X A;  5HN7 A;  5IMP A;  4LZ3 A;  3PDE A;  2F9K F;  3WCF A;  3WEF A;  3OAB A;  2Z7I A;  3CC9 A;  4LZC A;  1VG6 A;  3LVS A;  3N0G A;  5DHI A;  2DH4 A;  5B0K A;  4LOB A;  4RXC A;  2F89 F;  2EWG A;  2Q9Z A;  2OA6 A;  1WL3 A;  4XQT F;  1WL1 A;  3KRA A;  4KUX A;  4DWB A;  1YHM A;  3ZL6 A;  3WCD A;  1HXC A;  3KRF A;  1YYQ A;  3KRC A;  5IVG A;  1DI1 A;  4LZ0 A;  3LDW A;  1VG3 A;  1HM7 A;  4RYP A;  5ER8 A;  5IKA A;  1JFA A;  3P5R A;  3ID0 A;  3V1X A;  1V4J A;  1UBW A;  4DHD A;  5B03 A;  3MZV A;  3SAE A;  3S4J A;  2Q58 A;  4E1E A;  3P5P A;  2E90 A;  4ZQ8 A;  1HX9 A;  3LEE A;  5IK6 A;  2E91 A;  3BNY A;  3NPR A;  5E8K A;  5IMN A;  4QXS F;  4UMJ A;  2QIS A;  3N5J F;  3LGZ B;  5IN8 A; 
#chains in the Genus database with same CATH homology
 3SDV A;  1HM4 A;  2RAH A;  4DI5 A;  5JV1 F;  4KFA A;  3ICZ A;  3IPI A;  5A0I A;  5ERN A;  3WCA A;  3ASX A;  3AQC B;  3WEH A;  2F7M F;  4XQR F;  2Z4Y A;  3WEG A;  3M01 A;  4LFE A;  3OAC B;  2J5C A;  2OPN A;  4MC8 A;  2E8T A;  2I19 A;  3UCA A;  2AEL A;  5B01 A;  4NFI F;  3N1W F;  2Z4V A;  3N45 F;  1UBX A;  5ERM A;  4QPF A;  3NF2 A;  2F8C F;  3DYG A;  1YV5 A;  3QKC A;  3M00 A;  3W7F A;  2H8O A;  3EZ3 A;  4GP1 A;  3AE0 A;  4L2X F;  5KSX F;  3Q2Q A;  5E8L A;  1V4I A;  4DZW A;  4DEM F;  4LA5 A;  1YYT A;  4F62 A;  4OGU A;  3LSN A;  3P8L A;  4KWD A;  5AHU B;  3G4D A;  3WCB A;  3WSB A;  5HNA A;  5IM1 A;  4LTV A;  2Z4W A;  4KVI A;  3WCG A;  1KIY A;  4LXW A;  2E95 A;  3TS7 A;  3BNX A;  1ZW5 A;  4LLS A;  4N1Z F;  3PYB A;  3OAC A;  3QQV A;  2E8V A;  2Z4X A;  3TFN A;  1WL0 A;  3VJD A;  3WEJ A;  4EA0 A;  5ILJ A;  3M9U A;  2E8X A;  2PS5 A;  1WKZ A;  2ZCQ A;  3LLW A;  1N24 A;  1UBY A;  2F8Z F;  3WCI A;  4JVJ F;  2ZCR A;  3V1V A;  3LJI A;  4K10 A;  5B0I A;  3LZ9 A;  3KBK A;  5IK0 A;  4KQU A;  4LLT A;  3VJE A;  3ICK A;  5DGM F;  1YJ4 A;  4LTZ A;  3ACW A;  4HD1 A;  1DGP A;  5EAT A;  1VG7 A;  1N20 A;  3TC1 A;  4NKE A;  5B00 A;  5IL8 A;  5A0K A;  1YYR A;  3ACY A;  4E9Z A;  1FPS A;  3P8R A;  4RXA A;  2Q9Y A;  1HXA A;  2FOR A;  3WE9 A;  3WJK A;  4RNQ A;  2ZCS A;  4KVY A;  4JYX A;  3VJC A;  3G4F A;  4JXY A;  1N21 A;  3ICM A;  1UBV A;  5IL3 A;  4PVX F;  5DHK A;  2ZY1 A;  3VJB A;  5A0J A;  5AEL A;  1HXG A;  3B7L A;  5ILY A;  3CKE A;  2E93 A;  4H5E F;  4JZX A;  2E92 A;  4FP4 A;  3WCH A;  3WCJ A;  3WC9 A;  4KPJ A;  5DJR F;  4OMG A;  4EA1 A;  3WCM A;  2Z7H A;  1YHK A;  3SDQ A;  4DXJ A;  3NPK A;  1N1Z A;  4GA3 A;  3P41 A;  2AET A;  2E4O A;  4LFG A;  5DZ2 A;  5JV0 F;  5DW7 A;  1WMW A;  3RYW A;  4F6X A;  4WK5 A;  4KKM A;  3N5H F;  1VG2 A;  2F94 F;  5CG5 A;  3OYR A;  5AYP A;  3IBA A;  2Z4Z A;  5IK9 A;  1WY0 A;  3ZMB A;  4RXE A;  2Z50 A;  4GP2 A;  4Q23 A;  4EA2 A;  5HN9 A;  1KIZ A;  5ILH A;  2AZL A;  2AEK A;  3APZ A;  1YYS A;  4NG6 A;  3CP6 A;  2F92 F;  1VG4 A;  2Q80 A;  3PKO A;  2E94 A;  4LA6 A;  5DGS F;  3ZMC A;  3ADZ A;  3LOM A;  4KQ5 A;  3VJ9 A;  1N23 A;  5IKH A;  3V66 A;  5ILK A;  3SDU A;  5B0M A;  4JZB A;  2OGD A;  1YYU A;  3RBM A;  5DGN F;  3KB9 A;  2ZEV A;  3N0F A;  2Z52 A;  3AQB B;  3WSA A;  2Z78 A;  5DJV F;  5IMI A;  2ZEU A;  4OMH A;  3EFQ A;  2O1O A;  5DIQ F;  4DWG A;  4NUA A;  2ONG A;  2E8W A;  4OKM A;  3SDT A;  3WCL A;  5ILZ A;  5I1U A;  2AZK A;  3WJN A;  3LK5 A;  3KRP B;  4KVW A;  2J1O A;  3Q2Z A;  3ACX A;  4F6V A;  5H9D A;  5CG6 A;  2PS8 A;  3KRO B;  3DYH A;  5JUZ F;  5DJP F;  5ILD A;  1PS1 A;  4H5D F;  4LIX A;  5EAS A;  3WEK A;  3WJO A;  5JV2 F;  4NKF A;  2AZJ A;  3AQ0 A;  4LPG F;  3TFP A;  3M02 A;  1N22 A;  3LGK A;  3RYE A;  2ONH A;  2ZCO A;  1RQI A;  2PS6 A;  4PVY F;  3N3L F;  4LFV F;  3N3D A;  2FTZ A;  3DYF A;  2PS4 A;  1N1B A;  2OPM A;  3LG5 A;  4KQS A;  1V4H A;  2E8U A;  2PS7 A;  3N1V F;  5B02 A;  4GAX A;  3RMG A;  5AFX A;  4LPH F;  3ZCD A;  4XQS F;  3N6K F;  3Q30 A;  1JFG A;  2P1C A;  3PH7 A;  3Q1O A;  4N9U A;  3VJ8 A;  5B0J A;  3OAB B;  3KRP A;  1WL2 A;  4MC3 A;  3VJA A;  3S9V A;  3MAV A;  4RXD A;  3NRI A;  5E8H A;  5C05 A;  1V4K A;  3SDR A;  1RQJ A;  3N49 F;  4MC0 A;  2J1P A;  1V4E A;  3PYA A;  2VF6 A;  4KPD A;  3ICN A;  5ERO A;  4NFJ F;  3KRO A;  4E9U A;  3KRA B;  4P0W A;  1YHL A;  3KRF B;  5ILI A;  4KVD A;  3KRC B;  1YQ7 A;  3N46 F;  4JXN A;  4NFK F;  3WCE A;  3WCC A;  3LMD A;  5B0L A;  4FJQ A;  4H5C F;  3M0G A;  1RTR A;  3WEI A;  1EZF A;  3EGT A;  3TFV A;  4KK2 A;  5EAU A;  4P0V A;  3ZOU A;  4OKZ A;  4LUU A;  5JA0 F;  5HN8 A;  4P0X A;  5HN7 A;  5IMP A;  4LZ3 A;  3PDE A;  2F9K F;  3WCF A;  3WEF A;  3OAB A;  2Z7I A;  3CC9 A;  4LZC A;  1VG6 A;  3LVS A;  3N0G A;  5DHI A;  2DH4 A;  5B0K A;  4LOB A;  4RXC A;  2F89 F;  2EWG A;  2Q9Z A;  2OA6 A;  1WL3 A;  4XQT F;  1WL1 A;  3KRA A;  4KUX A;  4DWB A;  1YHM A;  3ZL6 A;  3WCD A;  1HXC A;  3KRF A;  1YYQ A;  3KRC A;  5IVG A;  1DI1 A;  4LZ0 A;  3LDW A;  1VG3 A;  1HM7 A;  4RYP A;  5ER8 A;  5IKA A;  1JFA A;  3P5R A;  3ID0 A;  3V1X A;  1V4J A;  1UBW A;  4DHD A;  5B03 A;  3MZV A;  3SAE A;  3S4J A;  2Q58 A;  4E1E A;  3P5P A;  2E90 A;  4ZQ8 A;  1HX9 A;  3LEE A;  5IK6 A;  2E91 A;  3BNY A;  3NPR A;  5E8K A;  5IMN A;  4QXS F;  4UMJ A;  2QIS A;  3N5J F;  3LGZ B;  5IN8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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