3Q30A

Human squalene synthase in complex with (2r,3r)-2-carboxymethoxy-3-[5-(2-naphthalenyl)pentyl]aminocarbonyl-3-[5-(2-naphthalenyl)pentyloxy]propionic acid
Total Genus 137
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
333
structure length
330
Chain Sequence
LSSSLKTCYKYLNQTSAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
molecule keywords Squalene synthase
publication title Discovery of a new 2-aminobenzhydrol template for highly potent squalene synthase inhibitors
pubmed doi rcsb
source organism Homo sapiens
total genus 137
structure length 330
sequence length 333
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2010-12-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3q30A00
5DGNF 1YYTA 2Z7IA 4P0WA 5KSXF 4RXAA 1WL2A 3P41A 3OACA 5EROA 2F8ZF 3UCAA 5IKAA 2OA6A 1KIYA 4KVWA 2PS8A 3Q2ZA 3WCBA 1YYUA 2Z4YA 1RTRA 1V4HA 1EZFA 3ADZA 3APZA 3WCHA 3KBKA 4H5CF 3M00A 3M02A 4LFGA 4OKZA 2E92A 2F94F 2PS5A 3PDEA 5IMPA 4LFVF 3WJKA 4NG6A 3VJBA 3WJNA 5IK0A 4DHDA 4KVIA 4KWDA 3NPRA 4RXDA 2J1OA 5B0LA 3KRFB 5JUZF 3P5RA 2F7MF 3WCMA 1N21A 5AHUB 3EFQA 4KQ5A 3WCDA 3WCFA 5A0KA 3LGKA 4H5EF 3LJIA 3VJCA 3WSBA 3ACXA 3LDWA 3PYAA 3SAEA 5HN7A 2E94A 4FJQA 3PKOA 4EA0A 2F92F 2ZCSA 3V1XA 2Z78A 1YYRA 2ONGA 3LMDA 3TFNA 3ICNA 2AETA 4LTVA 3TFPA 5A0IA 3WJOA 3KRFA 2ZCRA 3DYFA 4GAXA 4LA6A 1HXAA 5B0JA 4N1ZF 3WCGA 5IL8A 1YYQA 3ICZA 3DYHA 1HX9A 1YJ4A 4NKFA 4QXSF 2J5CA 4KUXA 4OMHA 3ZMBA 5B01A 3EGTA 4OKMA 4NUAA 1VG7A 4NFIF 4GA3A 5A0JA 1N1ZA 4FP4A 4F62A 3M0GA 3WSAA 4LFEA 4MC3A 3BNXA 1RQJA 2PS4A 2Q9ZA 4P0XA 2Q9YA 3LGZB 1V4KA 5ILYA 2Z4ZA 2FTZA 4HD1A 5AELA 4XQSF 5IKHA 5CG6A 4LPGF 4LIXA 3SDUA 2DH4A 5JV0F 3G4FA 1JFAA 2Z50A 2PS6A 3KRAA 1DGPA 3N6KF 4LUUA 1N24A 3V1VA 5ILKA 5IVGA 4KK2A 5ERMA 3SDQA 4KKMA 5ER8A 1YYSA 3ACWA 3WCCA 3KRPB 5IK9A 3TS7A 5DHKA 1WL3A 4DI5A 3LEEA 4KPDA 4JVJF 2E8TA 3KRCA 3VJAA 4P0VA 2AZKA 2E4OA 1WMWA 4ZQ8A 4L2XF 4UMJA 1KIZA 1HXGA 1VG4A 3Q1OA 3B7LA 2OPMA 3KRPA 1DI1A 3P8RA 3N5HF 5CG5A 1VG2A 4E1EA 2E95A 3NPKA 3CP6A 3N5JF 1HXCA 4F6VA 3VJDA 5ILZA 2QISA 3ICMA 3N1VF 3WCEA 2E8VA 3WEIA 2E90A 3VJ9A 4OMGA 2Z4XA 3M01A 5DIQF 4DWGA 4RXCA 1UBVA 2E8UA 2OPNA 3ACYA 2ZEVA 5B02A 3V66A 2FORA 5DJPF 3RYWA 4N9UA 2AEKA 3N45F 5DHIA 1N22A 4JZXA 4KPJA 5DZ2A 5ERNA 4DXJA 1V4IA 5E8LA 3LLWA 1JFGA 5IMIA 3OABB 1N20A 2P1CA 1FPSA 5JA0F 1WL0A 3LSNA 3N3LF 2Z7HA 3N46F 5E8KA 3KRAB 3SDVA 3IBAA 4XQTF 3WCIA 1YQ7A 4JXYA 5DJVF 1PS1A 4RYPA 1YHKA 2VF6A 3OABA 4WK5A 4PVYF 3W7FA 2E93A 5HN9A 5AFXA 4E9ZA 3N0GA 3KRCB 4EA2A 4LOBA 3DYGA 3NRIA 4Q23A 1ZW5A 2F8CF 3ICKA 3WEKA 4RNQA 3LZ9A 3IPIA 3KB9A 4LPHF 1WY0A 2I19A 3RYEA 3P8LA 2OGDA 1UBWA 3ZMCA 4E9UA 2Q58A 3PH7A 5B0KA 3N1WF 4LLSA 5DJRF 5C05A 3LG5A 1WL1A 3RBMA 2J1PA 2F9KF 1UBYA 3KROB 1V4JA 1N23A 4XQRF 2ZY1A 3LK5A 4KQUA 2ZEUA 4GP1A 5ILHA 2AZJA 5ILIA 3WEFA 4PVXF 2Z52A 5B03A 1VG3A 1YV5A 5H9DA 2ONHA 3WEJA 4JZBA 5DGSF 4LLTA 4RXEA 3Q30A 3QKCA 3MAVA 4MC0A 3QQVA 5DW7A 3KROA 3WE9A 1N1BA 5DGMF 3EZ3A 4MC8A 4NFKF 5JV1F 5B00A 5JV2F 2H8OA 3N0FA 3ZOUA 4JYXA 1HM7A 3LVSA 5I1UA 3AQ0A 1VG6A 5E8HA 3N3DA 3P5PA 3S9VA 5AYPA 5HN8A 3AE0A 3CC9A 4NFJF 3WCAA 5IM1A 1YHLA 5ILDA 2EWGA 1HM4A 3RMGA 2Z4WA 4QPFA 3LOMA 5B0MA 4NKEA 3SDRA 3AQBB 2Z4VA 4KFAA 2ZCOA 4LZ0A 3BNYA 4LZCA 2RAHA 1WKZA 4LXWA 4LZ3A 3PYBA 2AZLA 2AELA 1UBXA 3NF2A 4JXNA 2ZCQA 3WC9A 4DZWA 5EASA 3ZCDA 3AQCB 4KQSA 2Q80A 1YHMA 3Q2QA 4F6XA 3G4DA 4KVYA 3WCJA 4KVDA 5B0IA 4GP2A 5IL3A 4DWBA 4LTZA 3ID0A 5IK6A 3WEGA 1RQIA 5IN8A 3M9UA 3TC1A 2O1OA 3OYRA 3MZVA 4LA5A 3CKEA 2E8XA 2E8WA 5EAUA 3WEHA 3ZL6A 2PS7A 3OACB 5IMNA 4OGUA 4K10A 4EA1A 3S4JA 3ASXA 4DEMF 2E91A 3N49F 1V4EA 4H5DF 5ILJA 5EATA 5HNAA 3SDTA 2F89F 3WCLA 3VJEA 3TFVA 3VJ8A
chains in the Genus database with same CATH superfamily
5DGNF 1YYTA 2Z7IA 4P0WA 5KSXF 4RXAA 1WL2A 3P41A 3OACA 5EROA 2F8ZF 3UCAA 5IKAA 2OA6A 1KIYA 4KVWA 2PS8A 3Q2ZA 3WCBA 1YYUA 2Z4YA 1RTRA 1V4HA 1EZFA 3ADZA 3APZA 3WCHA 3KBKA 4H5CF 3M00A 3M02A 4LFGA 4OKZA 2E92A 2F94F 2PS5A 3PDEA 5IMPA 4LFVF 3WJKA 4NG6A 3VJBA 3WJNA 5IK0A 4DHDA 4KVIA 4KWDA 3NPRA 4RXDA 2J1OA 5B0LA 3KRFB 5JUZF 3P5RA 2F7MF 3WCMA 1N21A 5AHUB 3EFQA 4KQ5A 3WCDA 3WCFA 5A0KA 3LGKA 4H5EF 3LJIA 3VJCA 3WSBA 3ACXA 3LDWA 3PYAA 3SAEA 5HN7A 2E94A 4FJQA 3PKOA 4EA0A 2F92F 2ZCSA 3V1XA 2Z78A 1YYRA 2ONGA 3LMDA 3TFNA 3ICNA 2AETA 4LTVA 3TFPA 5A0IA 3WJOA 3KRFA 2ZCRA 3DYFA 4GAXA 4LA6A 1HXAA 5B0JA 4N1ZF 3WCGA 5IL8A 1YYQA 3ICZA 3DYHA 1HX9A 1YJ4A 4NKFA 4QXSF 2J5CA 4KUXA 4OMHA 3ZMBA 5B01A 3EGTA 4OKMA 4NUAA 1VG7A 4NFIF 4GA3A 5A0JA 1N1ZA 4FP4A 4F62A 3M0GA 3WSAA 4LFEA 4MC3A 3BNXA 1RQJA 2PS4A 2Q9ZA 4P0XA 2Q9YA 3LGZB 1V4KA 5ILYA 2Z4ZA 2FTZA 4HD1A 5AELA 4XQSF 5IKHA 5CG6A 4LPGF 4LIXA 3SDUA 2DH4A 5JV0F 3G4FA 1JFAA 2Z50A 2PS6A 3KRAA 1DGPA 3N6KF 4LUUA 1N24A 3V1VA 5ILKA 5IVGA 4KK2A 5ERMA 3SDQA 4KKMA 5ER8A 1YYSA 3ACWA 3WCCA 3KRPB 5IK9A 3TS7A 5DHKA 1WL3A 4DI5A 3LEEA 4KPDA 4JVJF 2E8TA 3KRCA 3VJAA 4P0VA 2AZKA 2E4OA 1WMWA 4ZQ8A 4L2XF 4UMJA 1KIZA 1HXGA 1VG4A 3Q1OA 3B7LA 2OPMA 3KRPA 1DI1A 3P8RA 3N5HF 5CG5A 1VG2A 4E1EA 2E95A 3NPKA 3CP6A 3N5JF 1HXCA 4F6VA 3VJDA 5ILZA 2QISA 3ICMA 3N1VF 3WCEA 2E8VA 3WEIA 2E90A 3VJ9A 4OMGA 2Z4XA 3M01A 5DIQF 4DWGA 4RXCA 1UBVA 2E8UA 2OPNA 3ACYA 2ZEVA 5B02A 3V66A 2FORA 5DJPF 3RYWA 4N9UA 2AEKA 3N45F 5DHIA 1N22A 4JZXA 4KPJA 5DZ2A 5ERNA 4DXJA 1V4IA 5E8LA 3LLWA 1JFGA 5IMIA 3OABB 1N20A 2P1CA 1FPSA 5JA0F 1WL0A 3LSNA 3N3LF 2Z7HA 3N46F 5E8KA 3KRAB 3SDVA 3IBAA 4XQTF 3WCIA 1YQ7A 4JXYA 5DJVF 1PS1A 4RYPA 1YHKA 2VF6A 3OABA 4WK5A 4PVYF 3W7FA 2E93A 5HN9A 5AFXA 4E9ZA 3N0GA 3KRCB 4EA2A 4LOBA 3DYGA 3NRIA 4Q23A 1ZW5A 2F8CF 3ICKA 3WEKA 4RNQA 3LZ9A 3IPIA 3KB9A 4LPHF 1WY0A 2I19A 3RYEA 3P8LA 2OGDA 1UBWA 3ZMCA 4E9UA 2Q58A 3PH7A 5B0KA 3N1WF 4LLSA 5DJRF 5C05A 3LG5A 1WL1A 3RBMA 2J1PA 2F9KF 1UBYA 3KROB 1V4JA 1N23A 4XQRF 2ZY1A 3LK5A 4KQUA 2ZEUA 4GP1A 5ILHA 2AZJA 5ILIA 3WEFA 4PVXF 2Z52A 5B03A 1VG3A 1YV5A 5H9DA 2ONHA 3WEJA 4JZBA 5DGSF 4LLTA 4RXEA 3Q30A 3QKCA 3MAVA 4MC0A 3QQVA 5DW7A 3KROA 3WE9A 1N1BA 5DGMF 3EZ3A 4MC8A 4NFKF 5JV1F 5B00A 5JV2F 2H8OA 3N0FA 3ZOUA 4JYXA 1HM7A 3LVSA 5I1UA 3AQ0A 1VG6A 5E8HA 3N3DA 3P5PA 3S9VA 5AYPA 5HN8A 3AE0A 3CC9A 4NFJF 3WCAA 5IM1A 1YHLA 5ILDA 2EWGA 1HM4A 3RMGA 2Z4WA 4QPFA 3LOMA 5B0MA 4NKEA 3SDRA 3AQBB 2Z4VA 4KFAA 2ZCOA 4LZ0A 3BNYA 4LZCA 2RAHA 1WKZA 4LXWA 4LZ3A 3PYBA 2AZLA 2AELA 1UBXA 3NF2A 4JXNA 2ZCQA 3WC9A 4DZWA 5EASA 3ZCDA 3AQCB 4KQSA 2Q80A 1YHMA 3Q2QA 4F6XA 3G4DA 4KVYA 3WCJA 4KVDA 5B0IA 4GP2A 5IL3A 4DWBA 4LTZA 3ID0A 5IK6A 3WEGA 1RQIA 5IN8A 3M9UA 3TC1A 2O1OA 3OYRA 3MZVA 4LA5A 3CKEA 2E8XA 2E8WA 5EAUA 3WEHA 3ZL6A 2PS7A 3OACB 5IMNA 4OGUA 4K10A 4EA1A 3S4JA 3ASXA 4DEMF 2E91A 3N49F 1V4EA 4H5DF 5ILJA 5EATA 5HNAA 3SDTA 2F89F 3WCLA 3VJEA 3TFVA 3VJ8A
chains in the Genus database with same CATH topology
5DGNF 1YYTA 2Z7IA 4P0WA 5KSXF 4RXAA 1WL2A 3P41A 3OACA 5EROA 2F8ZF 3UCAA 5IKAA 2OA6A 1KIYA 4KVWA 2PS8A 3Q2ZA 3WCBA 1YYUA 2Z4YA 1RTRA 1V4HA 1EZFA 3ADZA 3APZA 3WCHA 3KBKA 4H5CF 3M00A 3M02A 4LFGA 4OKZA 2E92A 2F94F 2PS5A 3PDEA 5IMPA 4LFVF 3WJKA 4NG6A 3VJBA 3WJNA 5IK0A 4DHDA 4KVIA 4KWDA 3NPRA 4RXDA 2J1OA 5B0LA 3KRFB 5JUZF 3P5RA 2F7MF 3WCMA 1N21A 5AHUB 3EFQA 4KQ5A 3WCDA 3WCFA 5A0KA 3LGKA 4H5EF 3LJIA 3VJCA 3WSBA 3ACXA 3LDWA 3PYAA 3SAEA 5HN7A 2E94A 4FJQA 3PKOA 4EA0A 2F92F 2ZCSA 3V1XA 2Z78A 1YYRA 2ONGA 3LMDA 3TFNA 3ICNA 2AETA 4LTVA 3TFPA 5A0IA 3WJOA 3KRFA 2ZCRA 3DYFA 4GAXA 4LA6A 1HXAA 5B0JA 4N1ZF 3WCGA 5IL8A 1YYQA 3ICZA 3DYHA 1HX9A 1YJ4A 4NKFA 4QXSF 2J5CA 4KUXA 4OMHA 3ZMBA 5B01A 3EGTA 4OKMA 4NUAA 1VG7A 4NFIF 4GA3A 5A0JA 1N1ZA 4FP4A 4F62A 3M0GA 3WSAA 4LFEA 4MC3A 3BNXA 1RQJA 2PS4A 2Q9ZA 4P0XA 2Q9YA 3LGZB 1V4KA 5ILYA 2Z4ZA 2FTZA 4HD1A 5AELA 4XQSF 5IKHA 5CG6A 4LPGF 4LIXA 3SDUA 2DH4A 5JV0F 3G4FA 1JFAA 2Z50A 2PS6A 3KRAA 1DGPA 3N6KF 4LUUA 1N24A 3V1VA 5ILKA 5IVGA 4KK2A 5ERMA 3SDQA 4KKMA 5ER8A 1YYSA 3ACWA 3WCCA 3KRPB 5IK9A 3TS7A 5DHKA 1WL3A 4DI5A 3LEEA 4KPDA 4JVJF 2E8TA 3KRCA 3VJAA 4P0VA 2AZKA 2E4OA 1WMWA 4ZQ8A 4L2XF 4UMJA 1KIZA 1HXGA 1VG4A 3Q1OA 3B7LA 2OPMA 3KRPA 1DI1A 3P8RA 3N5HF 5CG5A 1VG2A 4E1EA 2E95A 3NPKA 3CP6A 3N5JF 1HXCA 4F6VA 3VJDA 5ILZA 2QISA 3ICMA 3N1VF 3WCEA 2E8VA 3WEIA 2E90A 3VJ9A 4OMGA 2Z4XA 3M01A 5DIQF 4DWGA 4RXCA 1UBVA 2E8UA 2OPNA 3ACYA 2ZEVA 5B02A 3V66A 2FORA 5DJPF 3RYWA 4N9UA 2AEKA 3N45F 5DHIA 1N22A 4JZXA 4KPJA 5DZ2A 5ERNA 4DXJA 1V4IA 5E8LA 3LLWA 1JFGA 5IMIA 3OABB 1N20A 2P1CA 1FPSA 5JA0F 1WL0A 3LSNA 3N3LF 2Z7HA 3N46F 5E8KA 3KRAB 3SDVA 3IBAA 4XQTF 3WCIA 1YQ7A 4JXYA 5DJVF 1PS1A 4RYPA 1YHKA 2VF6A 3OABA 4WK5A 4PVYF 3W7FA 2E93A 5HN9A 5AFXA 4E9ZA 3N0GA 3KRCB 4EA2A 4LOBA 3DYGA 3NRIA 4Q23A 1ZW5A 2F8CF 3ICKA 3WEKA 4RNQA 3LZ9A 3IPIA 3KB9A 4LPHF 1WY0A 2I19A 3RYEA 3P8LA 2OGDA 1UBWA 3ZMCA 4E9UA 2Q58A 3PH7A 5B0KA 3N1WF 4LLSA 5DJRF 5C05A 3LG5A 1WL1A 3RBMA 2J1PA 2F9KF 1UBYA 3KROB 1V4JA 1N23A 4XQRF 2ZY1A 3LK5A 4KQUA 2ZEUA 4GP1A 5ILHA 2AZJA 5ILIA 3WEFA 4PVXF 2Z52A 5B03A 1VG3A 1YV5A 5H9DA 2ONHA 3WEJA 4JZBA 5DGSF 4LLTA 4RXEA 3Q30A 3QKCA 3MAVA 4MC0A 3QQVA 5DW7A 3KROA 3WE9A 1N1BA 5DGMF 3EZ3A 4MC8A 4NFKF 5JV1F 5B00A 5JV2F 2H8OA 3N0FA 3ZOUA 4JYXA 1HM7A 3LVSA 5I1UA 3AQ0A 1VG6A 5E8HA 3N3DA 3P5PA 3S9VA 5AYPA 5HN8A 3AE0A 3CC9A 4NFJF 3WCAA 5IM1A 1YHLA 5ILDA 2EWGA 1HM4A 3RMGA 2Z4WA 4QPFA 3LOMA 5B0MA 4NKEA 3SDRA 3AQBB 2Z4VA 4KFAA 2ZCOA 4LZ0A 3BNYA 4LZCA 2RAHA 1WKZA 4LXWA 4LZ3A 3PYBA 2AZLA 2AELA 1UBXA 3NF2A 4JXNA 2ZCQA 3WC9A 4DZWA 5EASA 3ZCDA 3AQCB 4KQSA 2Q80A 1YHMA 3Q2QA 4F6XA 3G4DA 4KVYA 3WCJA 4KVDA 5B0IA 4GP2A 5IL3A 4DWBA 4LTZA 3ID0A 5IK6A 3WEGA 1RQIA 5IN8A 3M9UA 3TC1A 2O1OA 3OYRA 3MZVA 4LA5A 3CKEA 2E8XA 2E8WA 5EAUA 3WEHA 3ZL6A 2PS7A 3OACB 5IMNA 4OGUA 4K10A 4EA1A 3S4JA 3ASXA 4DEMF 2E91A 3N49F 1V4EA 4H5DF 5ILJA 5EATA 5HNAA 3SDTA 2F89F 3WCLA 3VJEA 3TFVA 3VJ8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DGN F;  1YYT A;  2Z7I A;  4P0W A;  5KSX F;  4RXA A;  1WL2 A;  3P41 A;  3OAC A;  5ERO A;  2F8Z F;  3UCA A;  5IKA A;  2OA6 A;  1KIY A;  4KVW A;  2PS8 A;  3Q2Z A;  3WCB A;  1YYU A;  2Z4Y A;  1RTR A;  1V4H A;  1EZF A;  3ADZ A;  3APZ A;  3WCH A;  3KBK A;  4H5C F;  3M00 A;  3M02 A;  4LFG A;  4OKZ A;  2E92 A;  2F94 F;  2PS5 A;  3PDE A;  5IMP A;  4LFV F;  3WJK A;  4NG6 A;  3VJB A;  3WJN A;  5IK0 A;  4DHD A;  4KVI A;  4KWD A;  3NPR A;  4RXD A;  2J1O A;  5B0L A;  3KRF B;  5JUZ F;  3P5R A;  2F7M F;  3WCM A;  1N21 A;  5AHU B;  3EFQ A;  4KQ5 A;  3WCD A;  3WCF A;  5A0K A;  3LGK A;  4H5E F;  3LJI A;  3VJC A;  3WSB A;  3ACX A;  3LDW A;  3PYA A;  3SAE A;  5HN7 A;  2E94 A;  4FJQ A;  3PKO A;  4EA0 A;  2F92 F;  2ZCS A;  3V1X A;  2Z78 A;  1YYR A;  2ONG A;  3LMD A;  3TFN A;  3ICN A;  2AET A;  4LTV A;  3TFP A;  5A0I A;  3WJO A;  3KRF A;  2ZCR A;  3DYF A;  4GAX A;  4LA6 A;  1HXA A;  5B0J A;  4N1Z F;  3WCG A;  5IL8 A;  1YYQ A;  3ICZ A;  3DYH A;  1HX9 A;  1YJ4 A;  4NKF A;  4QXS F;  2J5C A;  4KUX A;  4OMH A;  3ZMB A;  5B01 A;  3EGT A;  4OKM A;  4NUA A;  1VG7 A;  4NFI F;  4GA3 A;  5A0J A;  1N1Z A;  4FP4 A;  4F62 A;  3M0G A;  3WSA A;  4LFE A;  4MC3 A;  3BNX A;  1RQJ A;  2PS4 A;  2Q9Z A;  4P0X A;  2Q9Y A;  3LGZ B;  1V4K A;  5ILY A;  2Z4Z A;  2FTZ A;  4HD1 A;  5AEL A;  4XQS F;  5IKH A;  5CG6 A;  4LPG F;  4LIX A;  3SDU A;  2DH4 A;  5JV0 F;  3G4F A;  1JFA A;  2Z50 A;  2PS6 A;  3KRA A;  1DGP A;  3N6K F;  4LUU A;  1N24 A;  3V1V A;  5ILK A;  5IVG A;  4KK2 A;  5ERM A;  3SDQ A;  4KKM A;  5ER8 A;  1YYS A;  3ACW A;  3WCC A;  3KRP B;  5IK9 A;  3TS7 A;  5DHK A;  1WL3 A;  4DI5 A;  3LEE A;  4KPD A;  4JVJ F;  2E8T A;  3KRC A;  3VJA A;  4P0V A;  2AZK A;  2E4O A;  1WMW A;  4ZQ8 A;  4L2X F;  4UMJ A;  1KIZ A;  1HXG A;  1VG4 A;  3Q1O A;  3B7L A;  2OPM A;  3KRP A;  1DI1 A;  3P8R A;  3N5H F;  5CG5 A;  1VG2 A;  4E1E A;  2E95 A;  3NPK A;  3CP6 A;  3N5J F;  1HXC A;  4F6V A;  3VJD A;  5ILZ A;  2QIS A;  3ICM A;  3N1V F;  3WCE A;  2E8V A;  3WEI A;  2E90 A;  3VJ9 A;  4OMG A;  2Z4X A;  3M01 A;  5DIQ F;  4DWG A;  4RXC A;  1UBV A;  2E8U A;  2OPN A;  3ACY A;  2ZEV A;  5B02 A;  3V66 A;  2FOR A;  5DJP F;  3RYW A;  4N9U A;  2AEK A;  3N45 F;  5DHI A;  1N22 A;  4JZX A;  4KPJ A;  5DZ2 A;  5ERN A;  4DXJ A;  1V4I A;  5E8L A;  3LLW A;  1JFG A;  5IMI A;  3OAB B;  1N20 A;  2P1C A;  1FPS A;  5JA0 F;  1WL0 A;  3LSN A;  3N3L F;  2Z7H A;  3N46 F;  5E8K A;  3KRA B;  3SDV A;  3IBA A;  4XQT F;  3WCI A;  1YQ7 A;  4JXY A;  5DJV F;  1PS1 A;  4RYP A;  1YHK A;  2VF6 A;  3OAB A;  4WK5 A;  4PVY F;  3W7F A;  2E93 A;  5HN9 A;  5AFX A;  4E9Z A;  3N0G A;  3KRC B;  4EA2 A;  4LOB A;  3DYG A;  3NRI A;  4Q23 A;  1ZW5 A;  2F8C F;  3ICK A;  3WEK A;  4RNQ A;  3LZ9 A;  3IPI A;  3KB9 A;  4LPH F;  1WY0 A;  2I19 A;  3RYE A;  3P8L A;  2OGD A;  1UBW A;  3ZMC A;  4E9U A;  2Q58 A;  3PH7 A;  5B0K A;  3N1W F;  4LLS A;  5DJR F;  5C05 A;  3LG5 A;  1WL1 A;  3RBM A;  2J1P A;  2F9K F;  1UBY A;  3KRO B;  1V4J A;  1N23 A;  4XQR F;  2ZY1 A;  3LK5 A;  4KQU A;  2ZEU A;  4GP1 A;  5ILH A;  2AZJ A;  5ILI A;  3WEF A;  4PVX F;  2Z52 A;  5B03 A;  1VG3 A;  1YV5 A;  5H9D A;  2ONH A;  3WEJ A;  4JZB A;  5DGS F;  4LLT A;  4RXE A;  3Q30 A;  3QKC A;  3MAV A;  4MC0 A;  3QQV A;  5DW7 A;  3KRO A;  3WE9 A;  1N1B A;  5DGM F;  3EZ3 A;  4MC8 A;  4NFK F;  5JV1 F;  5B00 A;  5JV2 F;  2H8O A;  3N0F A;  3ZOU A;  4JYX A;  1HM7 A;  3LVS A;  5I1U A;  3AQ0 A;  1VG6 A;  5E8H A;  3N3D A;  3P5P A;  3S9V A;  5AYP A;  5HN8 A;  3AE0 A;  3CC9 A;  4NFJ F;  3WCA A;  5IM1 A;  1YHL A;  5ILD A;  2EWG A;  1HM4 A;  3RMG A;  2Z4W A;  4QPF A;  3LOM A;  5B0M A;  4NKE A;  3SDR A;  3AQB B;  2Z4V A;  4KFA A;  2ZCO A;  4LZ0 A;  3BNY A;  4LZC A;  2RAH A;  1WKZ A;  4LXW A;  4LZ3 A;  3PYB A;  2AZL A;  2AEL A;  1UBX A;  3NF2 A;  4JXN A;  2ZCQ A;  3WC9 A;  4DZW A;  5EAS A;  3ZCD A;  3AQC B;  4KQS A;  2Q80 A;  1YHM A;  3Q2Q A;  4F6X A;  3G4D A;  4KVY A;  3WCJ A;  4KVD A;  5B0I A;  4GP2 A;  5IL3 A;  4DWB A;  4LTZ A;  3ID0 A;  5IK6 A;  3WEG A;  1RQI A;  5IN8 A;  3M9U A;  3TC1 A;  2O1O A;  3OYR A;  3MZV A;  4LA5 A;  3CKE A;  2E8X A;  2E8W A;  5EAU A;  3WEH A;  3ZL6 A;  2PS7 A;  3OAC B;  5IMN A;  4OGU A;  4K10 A;  4EA1 A;  3S4J A;  3ASX A;  4DEM F;  2E91 A;  3N49 F;  1V4E A;  4H5D F;  5ILJ A;  5EAT A;  5HNA A;  3SDT A;  2F89 F;  3WCL A;  3VJE A;  3TFV A;  3VJ8 A; 
#chains in the Genus database with same CATH topology
 5DGN F;  1YYT A;  2Z7I A;  4P0W A;  5KSX F;  4RXA A;  1WL2 A;  3P41 A;  3OAC A;  5ERO A;  2F8Z F;  3UCA A;  5IKA A;  2OA6 A;  1KIY A;  4KVW A;  2PS8 A;  3Q2Z A;  3WCB A;  1YYU A;  2Z4Y A;  1RTR A;  1V4H A;  1EZF A;  3ADZ A;  3APZ A;  3WCH A;  3KBK A;  4H5C F;  3M00 A;  3M02 A;  4LFG A;  4OKZ A;  2E92 A;  2F94 F;  2PS5 A;  3PDE A;  5IMP A;  4LFV F;  3WJK A;  4NG6 A;  3VJB A;  3WJN A;  5IK0 A;  4DHD A;  4KVI A;  4KWD A;  3NPR A;  4RXD A;  2J1O A;  5B0L A;  3KRF B;  5JUZ F;  3P5R A;  2F7M F;  3WCM A;  1N21 A;  5AHU B;  3EFQ A;  4KQ5 A;  3WCD A;  3WCF A;  5A0K A;  3LGK A;  4H5E F;  3LJI A;  3VJC A;  3WSB A;  3ACX A;  3LDW A;  3PYA A;  3SAE A;  5HN7 A;  2E94 A;  4FJQ A;  3PKO A;  4EA0 A;  2F92 F;  2ZCS A;  3V1X A;  2Z78 A;  1YYR A;  2ONG A;  3LMD A;  3TFN A;  3ICN A;  2AET A;  4LTV A;  3TFP A;  5A0I A;  3WJO A;  3KRF A;  2ZCR A;  3DYF A;  4GAX A;  4LA6 A;  1HXA A;  5B0J A;  4N1Z F;  3WCG A;  5IL8 A;  1YYQ A;  3ICZ A;  3DYH A;  1HX9 A;  1YJ4 A;  4NKF A;  4QXS F;  2J5C A;  4KUX A;  4OMH A;  3ZMB A;  5B01 A;  3EGT A;  4OKM A;  4NUA A;  1VG7 A;  4NFI F;  4GA3 A;  5A0J A;  1N1Z A;  4FP4 A;  4F62 A;  3M0G A;  3WSA A;  4LFE A;  4MC3 A;  3BNX A;  1RQJ A;  2PS4 A;  2Q9Z A;  4P0X A;  2Q9Y A;  3LGZ B;  1V4K A;  5ILY A;  2Z4Z A;  2FTZ A;  4HD1 A;  5AEL A;  4XQS F;  5IKH A;  5CG6 A;  4LPG F;  4LIX A;  3SDU A;  2DH4 A;  5JV0 F;  3G4F A;  1JFA A;  2Z50 A;  2PS6 A;  3KRA A;  1DGP A;  3N6K F;  4LUU A;  1N24 A;  3V1V A;  5ILK A;  5IVG A;  4KK2 A;  5ERM A;  3SDQ A;  4KKM A;  5ER8 A;  1YYS A;  3ACW A;  3WCC A;  3KRP B;  5IK9 A;  3TS7 A;  5DHK A;  1WL3 A;  4DI5 A;  3LEE A;  4KPD A;  4JVJ F;  2E8T A;  3KRC A;  3VJA A;  4P0V A;  2AZK A;  2E4O A;  1WMW A;  4ZQ8 A;  4L2X F;  4UMJ A;  1KIZ A;  1HXG A;  1VG4 A;  3Q1O A;  3B7L A;  2OPM A;  3KRP A;  1DI1 A;  3P8R A;  3N5H F;  5CG5 A;  1VG2 A;  4E1E A;  2E95 A;  3NPK A;  3CP6 A;  3N5J F;  1HXC A;  4F6V A;  3VJD A;  5ILZ A;  2QIS A;  3ICM A;  3N1V F;  3WCE A;  2E8V A;  3WEI A;  2E90 A;  3VJ9 A;  4OMG A;  2Z4X A;  3M01 A;  5DIQ F;  4DWG A;  4RXC A;  1UBV A;  2E8U A;  2OPN A;  3ACY A;  2ZEV A;  5B02 A;  3V66 A;  2FOR A;  5DJP F;  3RYW A;  4N9U A;  2AEK A;  3N45 F;  5DHI A;  1N22 A;  4JZX A;  4KPJ A;  5DZ2 A;  5ERN A;  4DXJ A;  1V4I A;  5E8L A;  3LLW A;  1JFG A;  5IMI A;  3OAB B;  1N20 A;  2P1C A;  1FPS A;  5JA0 F;  1WL0 A;  3LSN A;  3N3L F;  2Z7H A;  3N46 F;  5E8K A;  3KRA B;  3SDV A;  3IBA A;  4XQT F;  3WCI A;  1YQ7 A;  4JXY A;  5DJV F;  1PS1 A;  4RYP A;  1YHK A;  2VF6 A;  3OAB A;  4WK5 A;  4PVY F;  3W7F A;  2E93 A;  5HN9 A;  5AFX A;  4E9Z A;  3N0G A;  3KRC B;  4EA2 A;  4LOB A;  3DYG A;  3NRI A;  4Q23 A;  1ZW5 A;  2F8C F;  3ICK A;  3WEK A;  4RNQ A;  3LZ9 A;  3IPI A;  3KB9 A;  4LPH F;  1WY0 A;  2I19 A;  3RYE A;  3P8L A;  2OGD A;  1UBW A;  3ZMC A;  4E9U A;  2Q58 A;  3PH7 A;  5B0K A;  3N1W F;  4LLS A;  5DJR F;  5C05 A;  3LG5 A;  1WL1 A;  3RBM A;  2J1P A;  2F9K F;  1UBY A;  3KRO B;  1V4J A;  1N23 A;  4XQR F;  2ZY1 A;  3LK5 A;  4KQU A;  2ZEU A;  4GP1 A;  5ILH A;  2AZJ A;  5ILI A;  3WEF A;  4PVX F;  2Z52 A;  5B03 A;  1VG3 A;  1YV5 A;  5H9D A;  2ONH A;  3WEJ A;  4JZB A;  5DGS F;  4LLT A;  4RXE A;  3Q30 A;  3QKC A;  3MAV A;  4MC0 A;  3QQV A;  5DW7 A;  3KRO A;  3WE9 A;  1N1B A;  5DGM F;  3EZ3 A;  4MC8 A;  4NFK F;  5JV1 F;  5B00 A;  5JV2 F;  2H8O A;  3N0F A;  3ZOU A;  4JYX A;  1HM7 A;  3LVS A;  5I1U A;  3AQ0 A;  1VG6 A;  5E8H A;  3N3D A;  3P5P A;  3S9V A;  5AYP A;  5HN8 A;  3AE0 A;  3CC9 A;  4NFJ F;  3WCA A;  5IM1 A;  1YHL A;  5ILD A;  2EWG A;  1HM4 A;  3RMG A;  2Z4W A;  4QPF A;  3LOM A;  5B0M A;  4NKE A;  3SDR A;  3AQB B;  2Z4V A;  4KFA A;  2ZCO A;  4LZ0 A;  3BNY A;  4LZC A;  2RAH A;  1WKZ A;  4LXW A;  4LZ3 A;  3PYB A;  2AZL A;  2AEL A;  1UBX A;  3NF2 A;  4JXN A;  2ZCQ A;  3WC9 A;  4DZW A;  5EAS A;  3ZCD A;  3AQC B;  4KQS A;  2Q80 A;  1YHM A;  3Q2Q A;  4F6X A;  3G4D A;  4KVY A;  3WCJ A;  4KVD A;  5B0I A;  4GP2 A;  5IL3 A;  4DWB A;  4LTZ A;  3ID0 A;  5IK6 A;  3WEG A;  1RQI A;  5IN8 A;  3M9U A;  3TC1 A;  2O1O A;  3OYR A;  3MZV A;  4LA5 A;  3CKE A;  2E8X A;  2E8W A;  5EAU A;  3WEH A;  3ZL6 A;  2PS7 A;  3OAC B;  5IMN A;  4OGU A;  4K10 A;  4EA1 A;  3S4J A;  3ASX A;  4DEM F;  2E91 A;  3N49 F;  1V4E A;  4H5D F;  5ILJ A;  5EAT A;  5HNA A;  3SDT A;  2F89 F;  3WCL A;  3VJE A;  3TFV A;  3VJ8 A; 
#chains in the Genus database with same CATH homology
 5DGN F;  1YYT A;  2Z7I A;  4P0W A;  5KSX F;  4RXA A;  1WL2 A;  3P41 A;  3OAC A;  5ERO A;  2F8Z F;  3UCA A;  5IKA A;  2OA6 A;  1KIY A;  4KVW A;  2PS8 A;  3Q2Z A;  3WCB A;  1YYU A;  2Z4Y A;  1RTR A;  1V4H A;  1EZF A;  3ADZ A;  3APZ A;  3WCH A;  3KBK A;  4H5C F;  3M00 A;  3M02 A;  4LFG A;  4OKZ A;  2E92 A;  2F94 F;  2PS5 A;  3PDE A;  5IMP A;  4LFV F;  3WJK A;  4NG6 A;  3VJB A;  3WJN A;  5IK0 A;  4DHD A;  4KVI A;  4KWD A;  3NPR A;  4RXD A;  2J1O A;  5B0L A;  3KRF B;  5JUZ F;  3P5R A;  2F7M F;  3WCM A;  1N21 A;  5AHU B;  3EFQ A;  4KQ5 A;  3WCD A;  3WCF A;  5A0K A;  3LGK A;  4H5E F;  3LJI A;  3VJC A;  3WSB A;  3ACX A;  3LDW A;  3PYA A;  3SAE A;  5HN7 A;  2E94 A;  4FJQ A;  3PKO A;  4EA0 A;  2F92 F;  2ZCS A;  3V1X A;  2Z78 A;  1YYR A;  2ONG A;  3LMD A;  3TFN A;  3ICN A;  2AET A;  4LTV A;  3TFP A;  5A0I A;  3WJO A;  3KRF A;  2ZCR A;  3DYF A;  4GAX A;  4LA6 A;  1HXA A;  5B0J A;  4N1Z F;  3WCG A;  5IL8 A;  1YYQ A;  3ICZ A;  3DYH A;  1HX9 A;  1YJ4 A;  4NKF A;  4QXS F;  2J5C A;  4KUX A;  4OMH A;  3ZMB A;  5B01 A;  3EGT A;  4OKM A;  4NUA A;  1VG7 A;  4NFI F;  4GA3 A;  5A0J A;  1N1Z A;  4FP4 A;  4F62 A;  3M0G A;  3WSA A;  4LFE A;  4MC3 A;  3BNX A;  1RQJ A;  2PS4 A;  2Q9Z A;  4P0X A;  2Q9Y A;  3LGZ B;  1V4K A;  5ILY A;  2Z4Z A;  2FTZ A;  4HD1 A;  5AEL A;  4XQS F;  5IKH A;  5CG6 A;  4LPG F;  4LIX A;  3SDU A;  2DH4 A;  5JV0 F;  3G4F A;  1JFA A;  2Z50 A;  2PS6 A;  3KRA A;  1DGP A;  3N6K F;  4LUU A;  1N24 A;  3V1V A;  5ILK A;  5IVG A;  4KK2 A;  5ERM A;  3SDQ A;  4KKM A;  5ER8 A;  1YYS A;  3ACW A;  3WCC A;  3KRP B;  5IK9 A;  3TS7 A;  5DHK A;  1WL3 A;  4DI5 A;  3LEE A;  4KPD A;  4JVJ F;  2E8T A;  3KRC A;  3VJA A;  4P0V A;  2AZK A;  2E4O A;  1WMW A;  4ZQ8 A;  4L2X F;  4UMJ A;  1KIZ A;  1HXG A;  1VG4 A;  3Q1O A;  3B7L A;  2OPM A;  3KRP A;  1DI1 A;  3P8R A;  3N5H F;  5CG5 A;  1VG2 A;  4E1E A;  2E95 A;  3NPK A;  3CP6 A;  3N5J F;  1HXC A;  4F6V A;  3VJD A;  5ILZ A;  2QIS A;  3ICM A;  3N1V F;  3WCE A;  2E8V A;  3WEI A;  2E90 A;  3VJ9 A;  4OMG A;  2Z4X A;  3M01 A;  5DIQ F;  4DWG A;  4RXC A;  1UBV A;  2E8U A;  2OPN A;  3ACY A;  2ZEV A;  5B02 A;  3V66 A;  2FOR A;  5DJP F;  3RYW A;  4N9U A;  2AEK A;  3N45 F;  5DHI A;  1N22 A;  4JZX A;  4KPJ A;  5DZ2 A;  5ERN A;  4DXJ A;  1V4I A;  5E8L A;  3LLW A;  1JFG A;  5IMI A;  3OAB B;  1N20 A;  2P1C A;  1FPS A;  5JA0 F;  1WL0 A;  3LSN A;  3N3L F;  2Z7H A;  3N46 F;  5E8K A;  3KRA B;  3SDV A;  3IBA A;  4XQT F;  3WCI A;  1YQ7 A;  4JXY A;  5DJV F;  1PS1 A;  4RYP A;  1YHK A;  2VF6 A;  3OAB A;  4WK5 A;  4PVY F;  3W7F A;  2E93 A;  5HN9 A;  5AFX A;  4E9Z A;  3N0G A;  3KRC B;  4EA2 A;  4LOB A;  3DYG A;  3NRI A;  4Q23 A;  1ZW5 A;  2F8C F;  3ICK A;  3WEK A;  4RNQ A;  3LZ9 A;  3IPI A;  3KB9 A;  4LPH F;  1WY0 A;  2I19 A;  3RYE A;  3P8L A;  2OGD A;  1UBW A;  3ZMC A;  4E9U A;  2Q58 A;  3PH7 A;  5B0K A;  3N1W F;  4LLS A;  5DJR F;  5C05 A;  3LG5 A;  1WL1 A;  3RBM A;  2J1P A;  2F9K F;  1UBY A;  3KRO B;  1V4J A;  1N23 A;  4XQR F;  2ZY1 A;  3LK5 A;  4KQU A;  2ZEU A;  4GP1 A;  5ILH A;  2AZJ A;  5ILI A;  3WEF A;  4PVX F;  2Z52 A;  5B03 A;  1VG3 A;  1YV5 A;  5H9D A;  2ONH A;  3WEJ A;  4JZB A;  5DGS F;  4LLT A;  4RXE A;  3Q30 A;  3QKC A;  3MAV A;  4MC0 A;  3QQV A;  5DW7 A;  3KRO A;  3WE9 A;  1N1B A;  5DGM F;  3EZ3 A;  4MC8 A;  4NFK F;  5JV1 F;  5B00 A;  5JV2 F;  2H8O A;  3N0F A;  3ZOU A;  4JYX A;  1HM7 A;  3LVS A;  5I1U A;  3AQ0 A;  1VG6 A;  5E8H A;  3N3D A;  3P5P A;  3S9V A;  5AYP A;  5HN8 A;  3AE0 A;  3CC9 A;  4NFJ F;  3WCA A;  5IM1 A;  1YHL A;  5ILD A;  2EWG A;  1HM4 A;  3RMG A;  2Z4W A;  4QPF A;  3LOM A;  5B0M A;  4NKE A;  3SDR A;  3AQB B;  2Z4V A;  4KFA A;  2ZCO A;  4LZ0 A;  3BNY A;  4LZC A;  2RAH A;  1WKZ A;  4LXW A;  4LZ3 A;  3PYB A;  2AZL A;  2AEL A;  1UBX A;  3NF2 A;  4JXN A;  2ZCQ A;  3WC9 A;  4DZW A;  5EAS A;  3ZCD A;  3AQC B;  4KQS A;  2Q80 A;  1YHM A;  3Q2Q A;  4F6X A;  3G4D A;  4KVY A;  3WCJ A;  4KVD A;  5B0I A;  4GP2 A;  5IL3 A;  4DWB A;  4LTZ A;  3ID0 A;  5IK6 A;  3WEG A;  1RQI A;  5IN8 A;  3M9U A;  3TC1 A;  2O1O A;  3OYR A;  3MZV A;  4LA5 A;  3CKE A;  2E8X A;  2E8W A;  5EAU A;  3WEH A;  3ZL6 A;  2PS7 A;  3OAC B;  5IMN A;  4OGU A;  4K10 A;  4EA1 A;  3S4J A;  3ASX A;  4DEM F;  2E91 A;  3N49 F;  1V4E A;  4H5D F;  5ILJ A;  5EAT A;  5HNA A;  3SDT A;  2F89 F;  3WCL A;  3VJE A;  3TFV A;  3VJ8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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