3Q30A

Human squalene synthase in complex with (2r,3r)-2-carboxymethoxy-3-[5-(2-naphthalenyl)pentyl]aminocarbonyl-3-[5-(2-naphthalenyl)pentyloxy]propionic acid
Total Genus 137
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
333
structure length
330
Chain Sequence
LSSSLKTCYKYLNQTSAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of a new 2-aminobenzhydrol template for highly potent squalene synthase inhibitors
pubmed doi rcsb
molecule keywords Squalene synthase
molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
total genus 137
structure length 330
sequence length 333
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2010-12-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3q30A00
1HM4A 2E92A 3EZ3A 5EATA 4L2XF 3MZVA 4KQ5A 3WC9A 5ERMA 3SDTA 4LFGA 2Z4VA 4NUAA 1N24A 2Q9YA 3OABB 4MC3A 2Z52A 4LPGF 3WEJA 2F89F 2E95A 5IK9A 5A0JA 4NFJF 3PH7A 5ILIA 3WJKA 5ILHA 4KQSA 5IM1A 2EWGA 5ILJA 5IN8A 3ADZA 2PS7A 3RYEA 2ONHA 4GP2A 2Z78A 4FJQA 3IPIA 5HNAA 3WEFA 5A0KA 3AE0A 1HXAA 1WL1A 3LMDA 5KSXF 3M9UA 2J1PA 1YYUA 3B7LA 3ICZA 1YV5A 2ZCOA 2PS5A 3P5RA 2Q80A 3N3DA 2AZKA 1WMWA 3MAVA 3AQBB 3KRFA 2F8ZF 2J1OA 4F6VA 3CP6A 4NFIF 2VF6A 3P8RA 3LSNA 2Z7HA 2P1CA 4LTZA 3G4DA 3CKEA 3VJBA 3EGTA 3QKCA 2ZCRA 4DEMF 2ZEUA 3OACA 4LOBA 4RXDA 2F8CF 1YQ7A 3SDUA 3SDRA 5IL3A 5I1UA 4KVIA 3TFPA 3P41A 3LLWA 4E1EA 3N0FA 3LGKA 1YJ4A 3OACB 1N1ZA 3N45F 1FPSA 1WL3A 5HN9A 3KRPB 4XQTF 3RBMA 3WEGA 2E91A 3BNYA 4DWBA 1YHKA 3KRCB 4FP4A 3WSBA 1UBWA 5DJRF 3WCJA 5ILDA 4KVWA 2PS8A 1HXCA 5IKHA 3OABA 3WJNA 3WEIA 1N21A 1V4JA 4LLSA 4KUXA 4MC0A 3WEKA 2Z4XA 4NKEA 3KROB 4DI5A 2Z7IA 5JA0F 4XQRF 1RTRA 5C05A 1V4IA 4PVXF 3VJAA 3LK5A 4P0WA 4NKFA 4E9UA 3G4FA 3ZCDA 1EZFA 3Q1OA 5JV0F 2ZCSA 4KQUA 2Z4WA 3KB9A 5JUZF 3M0GA 4LA6A 1HX9A 1WY0A 5DIQF 5HN8A 3ZL6A 1N20A 4KWDA 4KVDA 5IMNA 4LA5A 1UBYA 1WL0A 4WK5A 5E8HA 1RQIA 4H5CF 4OGUA 3Q2ZA 4KKMA 5DHIA 3M02A 1YYQA 2Z4ZA 2OPNA 3ACWA 5IKAA 4H5DF 3AQCB 3WSAA 5JV2F 2Z50A 3SAEA 3NPRA 3WCHA 3N46F 3APZA 5A0IA 2E8UA 3ICMA 1YYSA 3PDEA 2ZEVA 4KVYA 1ZW5A 2Q9ZA 4XQSF 3WE9A 3ACXA 4N9UA 4PVYF 5ERNA 3WCBA 4LFVF 4RXEA 4NG6A 4MC8A 3Q30A 4JXNA 3ACYA 3OYRA 4KFAA 2E8VA 2ZCQA 3DYHA 5IMPA 4ZQ8A 5B0MA 5AELA 4GA3A 4Q23A 3WCAA 3KRPA 1VG4A 1PS1A 3LOMA 3LZ9A 3ASXA 5B0JA 3VJEA 2FTZA 3KRCA 2F92F 2ZY1A 3ZMCA 4DWGA 3V1VA 3N1VF 3SDVA 5DGMF 2OPMA 4GP1A 3VJCA 3QQVA 3Q2QA 1VG3A 3CC9A 4LZCA 1VG6A 2PS6A 3NF2A 3UCAA 2DH4A 3PYAA 4K10A 1KIYA 3N6KF 4KPDA 3N0GA 2F7MF 3KROA 1N1BA 4LPHF 3TFVA 5ILYA 3V1XA 3S4JA 3N5HF 5B00A 2Q58A 4QPFA 5DGSF 2E8XA 3TC1A 2E94A 3WCCA 5ER8A 3LGZB 1YHMA 5B03A 4JZXA 3VJ8A 5DGNF 5JV1F 4EA2A 3N5JF 3S9VA 4JZBA 3WCGA 1WKZA 3DYGA 3AQ0A 4EA0A 3EFQA 1RQJA 3P8LA 4NFKF 5AFXA 5IVGA 3WCFA 1UBXA 1V4EA 1DGPA 2OGDA 2OA6A 1V4KA 4OKZA 3VJDA 2PS4A 4RNQA 4OMHA 4QXSF 4HD1A 5DZ2A 3PKOA 3IBAA 2E8WA 3WEHA 4KK2A 3DYFA 3N1WF 2AETA 2RAHA 1UBVA 4GAXA 2J5CA 3N49F 1VG7A 5ILZA 2AELA 4KPJA 4DXJA 5AHUB 1DI1A 2E4OA 4P0XA 5IL8A 4LUUA 3W7FA 5B0KA 3VJ9A 2ONGA 4DZWA 3P5PA 5DJPF 3ICKA 3N3LF 3TS7A 2O1OA 5IK6A 3ID0A 1YYRA 2FORA 1YHLA 3BNXA 4DHDA 1N23A 4LLTA 4LZ3A 5B01A 3RYWA 1JFGA 3KRAA 5DHKA 3WCDA 3ICNA 4UMJA 5EROA 4LFEA 4EA1A 4RXAA 2E8TA 3WCMA 4JXYA 4RXCA 4RYPA 5DJVF 3KRAB 3LG5A 5AYPA 1VG2A 1WL2A 1N22A 1JFAA 3NRIA 4JYXA 2E90A 5E8KA 3WCLA 2QISA 3LEEA 2AZLA 2F9KF 5HN7A 1V4HA 5B0LA 2Z4YA 3LDWA 4LXWA 3KRFB 2E93A 4N1ZF 2F94F 5IMIA 5EAUA 5IK0A 2H8OA 4JVJF 5B02A 3SDQA 3WCEA 4LIXA 5H9DA 2AZJA 1HM7A 1KIZA 4LTVA 4OMGA 5E8LA 3TFNA 3ZOUA 3KBKA 3LVSA 4OKMA 3ZMBA 3V66A 5CG6A 3LJIA 4P0VA 4E9ZA 5CG5A 3NPKA 5B0IA 1HXGA 3RMGA 3M00A 3PYBA 5EASA 3WJOA 4F62A 2AEKA 4LZ0A 5DW7A 3M01A 1YYTA 5ILKA 2I19A 4H5EF 4F6XA 3WCIA
chains in the Genus database with same CATH superfamily
1HM4A 2E92A 3EZ3A 5EATA 4L2XF 3MZVA 4KQ5A 3WC9A 5ERMA 3SDTA 4LFGA 2Z4VA 4NUAA 1N24A 2Q9YA 3OABB 4MC3A 2Z52A 4LPGF 3WEJA 2F89F 2E95A 5IK9A 5A0JA 4NFJF 3PH7A 5ILIA 3WJKA 5ILHA 4KQSA 5IM1A 2EWGA 5ILJA 5IN8A 3ADZA 2PS7A 3RYEA 2ONHA 4GP2A 2Z78A 4FJQA 3IPIA 5HNAA 3WEFA 5A0KA 3AE0A 1HXAA 1WL1A 3LMDA 5KSXF 3M9UA 2J1PA 1YYUA 3B7LA 3ICZA 1YV5A 2ZCOA 2PS5A 3P5RA 2Q80A 3N3DA 2AZKA 1WMWA 3MAVA 3AQBB 3KRFA 2F8ZF 2J1OA 4F6VA 3CP6A 4NFIF 2VF6A 3P8RA 3LSNA 2Z7HA 2P1CA 4LTZA 3G4DA 3CKEA 3VJBA 3EGTA 3QKCA 2ZCRA 4DEMF 2ZEUA 3OACA 4LOBA 4RXDA 2F8CF 1YQ7A 3SDUA 3SDRA 5IL3A 5I1UA 4KVIA 3TFPA 3P41A 3LLWA 4E1EA 3N0FA 3LGKA 1YJ4A 3OACB 1N1ZA 3N45F 1FPSA 1WL3A 5HN9A 3KRPB 4XQTF 3RBMA 3WEGA 2E91A 3BNYA 4DWBA 1YHKA 3KRCB 4FP4A 3WSBA 1UBWA 5DJRF 3WCJA 5ILDA 4KVWA 2PS8A 1HXCA 5IKHA 3OABA 3WJNA 3WEIA 1N21A 1V4JA 4LLSA 4KUXA 4MC0A 3WEKA 2Z4XA 4NKEA 3KROB 4DI5A 2Z7IA 5JA0F 4XQRF 1RTRA 5C05A 1V4IA 4PVXF 3VJAA 3LK5A 4P0WA 4NKFA 4E9UA 3G4FA 3ZCDA 1EZFA 3Q1OA 5JV0F 2ZCSA 4KQUA 2Z4WA 3KB9A 5JUZF 3M0GA 4LA6A 1HX9A 1WY0A 5DIQF 5HN8A 3ZL6A 1N20A 4KWDA 4KVDA 5IMNA 4LA5A 1UBYA 1WL0A 4WK5A 5E8HA 1RQIA 4H5CF 4OGUA 3Q2ZA 4KKMA 5DHIA 3M02A 1YYQA 2Z4ZA 2OPNA 3ACWA 5IKAA 4H5DF 3AQCB 3WSAA 5JV2F 2Z50A 3SAEA 3NPRA 3WCHA 3N46F 3APZA 5A0IA 2E8UA 3ICMA 1YYSA 3PDEA 2ZEVA 4KVYA 1ZW5A 2Q9ZA 4XQSF 3WE9A 3ACXA 4N9UA 4PVYF 5ERNA 3WCBA 4LFVF 4RXEA 4NG6A 4MC8A 3Q30A 4JXNA 3ACYA 3OYRA 4KFAA 2E8VA 2ZCQA 3DYHA 5IMPA 4ZQ8A 5B0MA 5AELA 4GA3A 4Q23A 3WCAA 3KRPA 1VG4A 1PS1A 3LOMA 3LZ9A 3ASXA 5B0JA 3VJEA 2FTZA 3KRCA 2F92F 2ZY1A 3ZMCA 4DWGA 3V1VA 3N1VF 3SDVA 5DGMF 2OPMA 4GP1A 3VJCA 3QQVA 3Q2QA 1VG3A 3CC9A 4LZCA 1VG6A 2PS6A 3NF2A 3UCAA 2DH4A 3PYAA 4K10A 1KIYA 3N6KF 4KPDA 3N0GA 2F7MF 3KROA 1N1BA 4LPHF 3TFVA 5ILYA 3V1XA 3S4JA 3N5HF 5B00A 2Q58A 4QPFA 5DGSF 2E8XA 3TC1A 2E94A 3WCCA 5ER8A 3LGZB 1YHMA 5B03A 4JZXA 3VJ8A 5DGNF 5JV1F 4EA2A 3N5JF 3S9VA 4JZBA 3WCGA 1WKZA 3DYGA 3AQ0A 4EA0A 3EFQA 1RQJA 3P8LA 4NFKF 5AFXA 5IVGA 3WCFA 1UBXA 1V4EA 1DGPA 2OGDA 2OA6A 1V4KA 4OKZA 3VJDA 2PS4A 4RNQA 4OMHA 4QXSF 4HD1A 5DZ2A 3PKOA 3IBAA 2E8WA 3WEHA 4KK2A 3DYFA 3N1WF 2AETA 2RAHA 1UBVA 4GAXA 2J5CA 3N49F 1VG7A 5ILZA 2AELA 4KPJA 4DXJA 5AHUB 1DI1A 2E4OA 4P0XA 5IL8A 4LUUA 3W7FA 5B0KA 3VJ9A 2ONGA 4DZWA 3P5PA 5DJPF 3ICKA 3N3LF 3TS7A 2O1OA 5IK6A 3ID0A 1YYRA 2FORA 1YHLA 3BNXA 4DHDA 1N23A 4LLTA 4LZ3A 5B01A 3RYWA 1JFGA 3KRAA 5DHKA 3WCDA 3ICNA 4UMJA 5EROA 4LFEA 4EA1A 4RXAA 2E8TA 3WCMA 4JXYA 4RXCA 4RYPA 5DJVF 3KRAB 3LG5A 5AYPA 1VG2A 1WL2A 1N22A 1JFAA 3NRIA 4JYXA 2E90A 5E8KA 3WCLA 2QISA 3LEEA 2AZLA 2F9KF 5HN7A 1V4HA 5B0LA 2Z4YA 3LDWA 4LXWA 3KRFB 2E93A 4N1ZF 2F94F 5IMIA 5EAUA 5IK0A 2H8OA 4JVJF 5B02A 3SDQA 3WCEA 4LIXA 5H9DA 2AZJA 1HM7A 1KIZA 4LTVA 4OMGA 5E8LA 3TFNA 3ZOUA 3KBKA 3LVSA 4OKMA 3ZMBA 3V66A 5CG6A 3LJIA 4P0VA 4E9ZA 5CG5A 3NPKA 5B0IA 1HXGA 3RMGA 3M00A 3PYBA 5EASA 3WJOA 4F62A 2AEKA 4LZ0A 5DW7A 3M01A 1YYTA 5ILKA 2I19A 4H5EF 4F6XA 3WCIA
chains in the Genus database with same CATH topology
1HM4A 2E92A 3EZ3A 5EATA 4L2XF 3MZVA 4KQ5A 3WC9A 5ERMA 3SDTA 4LFGA 2Z4VA 4NUAA 1N24A 2Q9YA 3OABB 4MC3A 2Z52A 4LPGF 3WEJA 2F89F 2E95A 5IK9A 5A0JA 4NFJF 3PH7A 5ILIA 3WJKA 5ILHA 4KQSA 5IM1A 2EWGA 5ILJA 5IN8A 3ADZA 2PS7A 3RYEA 2ONHA 4GP2A 2Z78A 4FJQA 3IPIA 5HNAA 3WEFA 5A0KA 3AE0A 1HXAA 1WL1A 3LMDA 5KSXF 3M9UA 2J1PA 1YYUA 3B7LA 3ICZA 1YV5A 2ZCOA 2PS5A 3P5RA 2Q80A 3N3DA 2AZKA 1WMWA 3MAVA 3AQBB 3KRFA 2F8ZF 2J1OA 4F6VA 3CP6A 4NFIF 2VF6A 3P8RA 3LSNA 2Z7HA 2P1CA 4LTZA 3G4DA 3CKEA 3VJBA 3EGTA 3QKCA 2ZCRA 4DEMF 2ZEUA 3OACA 4LOBA 4RXDA 2F8CF 1YQ7A 3SDUA 3SDRA 5IL3A 5I1UA 4KVIA 3TFPA 3P41A 3LLWA 4E1EA 3N0FA 3LGKA 1YJ4A 3OACB 1N1ZA 3N45F 1FPSA 1WL3A 5HN9A 3KRPB 4XQTF 3RBMA 3WEGA 2E91A 3BNYA 4DWBA 1YHKA 3KRCB 4FP4A 3WSBA 1UBWA 5DJRF 3WCJA 5ILDA 4KVWA 2PS8A 1HXCA 5IKHA 3OABA 3WJNA 3WEIA 1N21A 1V4JA 4LLSA 4KUXA 4MC0A 3WEKA 2Z4XA 4NKEA 3KROB 4DI5A 2Z7IA 5JA0F 4XQRF 1RTRA 5C05A 1V4IA 4PVXF 3VJAA 3LK5A 4P0WA 4NKFA 4E9UA 3G4FA 3ZCDA 1EZFA 3Q1OA 5JV0F 2ZCSA 4KQUA 2Z4WA 3KB9A 5JUZF 3M0GA 4LA6A 1HX9A 1WY0A 5DIQF 5HN8A 3ZL6A 1N20A 4KWDA 4KVDA 5IMNA 4LA5A 1UBYA 1WL0A 4WK5A 5E8HA 1RQIA 4H5CF 4OGUA 3Q2ZA 4KKMA 5DHIA 3M02A 1YYQA 2Z4ZA 2OPNA 3ACWA 5IKAA 4H5DF 3AQCB 3WSAA 5JV2F 2Z50A 3SAEA 3NPRA 3WCHA 3N46F 3APZA 5A0IA 2E8UA 3ICMA 1YYSA 3PDEA 2ZEVA 4KVYA 1ZW5A 2Q9ZA 4XQSF 3WE9A 3ACXA 4N9UA 4PVYF 5ERNA 3WCBA 4LFVF 4RXEA 4NG6A 4MC8A 3Q30A 4JXNA 3ACYA 3OYRA 4KFAA 2E8VA 2ZCQA 3DYHA 5IMPA 4ZQ8A 5B0MA 5AELA 4GA3A 4Q23A 3WCAA 3KRPA 1VG4A 1PS1A 3LOMA 3LZ9A 3ASXA 5B0JA 3VJEA 2FTZA 3KRCA 2F92F 2ZY1A 3ZMCA 4DWGA 3V1VA 3N1VF 3SDVA 5DGMF 2OPMA 4GP1A 3VJCA 3QQVA 3Q2QA 1VG3A 3CC9A 4LZCA 1VG6A 2PS6A 3NF2A 3UCAA 2DH4A 3PYAA 4K10A 1KIYA 3N6KF 4KPDA 3N0GA 2F7MF 3KROA 1N1BA 4LPHF 3TFVA 5ILYA 3V1XA 3S4JA 3N5HF 5B00A 2Q58A 4QPFA 5DGSF 2E8XA 3TC1A 2E94A 3WCCA 5ER8A 3LGZB 1YHMA 5B03A 4JZXA 3VJ8A 5DGNF 5JV1F 4EA2A 3N5JF 3S9VA 4JZBA 3WCGA 1WKZA 3DYGA 3AQ0A 4EA0A 3EFQA 1RQJA 3P8LA 4NFKF 5AFXA 5IVGA 3WCFA 1UBXA 1V4EA 1DGPA 2OGDA 2OA6A 1V4KA 4OKZA 3VJDA 2PS4A 4RNQA 4OMHA 4QXSF 4HD1A 5DZ2A 3PKOA 3IBAA 2E8WA 3WEHA 4KK2A 3DYFA 3N1WF 2AETA 2RAHA 1UBVA 4GAXA 2J5CA 3N49F 1VG7A 5ILZA 2AELA 4KPJA 4DXJA 5AHUB 1DI1A 2E4OA 4P0XA 5IL8A 4LUUA 3W7FA 5B0KA 3VJ9A 2ONGA 4DZWA 3P5PA 5DJPF 3ICKA 3N3LF 3TS7A 2O1OA 5IK6A 3ID0A 1YYRA 2FORA 1YHLA 3BNXA 4DHDA 1N23A 4LLTA 4LZ3A 5B01A 3RYWA 1JFGA 3KRAA 5DHKA 3WCDA 3ICNA 4UMJA 5EROA 4LFEA 4EA1A 4RXAA 2E8TA 3WCMA 4JXYA 4RXCA 4RYPA 5DJVF 3KRAB 3LG5A 5AYPA 1VG2A 1WL2A 1N22A 1JFAA 3NRIA 4JYXA 2E90A 5E8KA 3WCLA 2QISA 3LEEA 2AZLA 2F9KF 5HN7A 1V4HA 5B0LA 2Z4YA 3LDWA 4LXWA 3KRFB 2E93A 4N1ZF 2F94F 5IMIA 5EAUA 5IK0A 2H8OA 4JVJF 5B02A 3SDQA 3WCEA 4LIXA 5H9DA 2AZJA 1HM7A 1KIZA 4LTVA 4OMGA 5E8LA 3TFNA 3ZOUA 3KBKA 3LVSA 4OKMA 3ZMBA 3V66A 5CG6A 3LJIA 4P0VA 4E9ZA 5CG5A 3NPKA 5B0IA 1HXGA 3RMGA 3M00A 3PYBA 5EASA 3WJOA 4F62A 2AEKA 4LZ0A 5DW7A 3M01A 1YYTA 5ILKA 2I19A 4H5EF 4F6XA 3WCIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HM4 A;  2E92 A;  3EZ3 A;  5EAT A;  4L2X F;  3MZV A;  4KQ5 A;  3WC9 A;  5ERM A;  3SDT A;  4LFG A;  2Z4V A;  4NUA A;  1N24 A;  2Q9Y A;  3OAB B;  4MC3 A;  2Z52 A;  4LPG F;  3WEJ A;  2F89 F;  2E95 A;  5IK9 A;  5A0J A;  4NFJ F;  3PH7 A;  5ILI A;  3WJK A;  5ILH A;  4KQS A;  5IM1 A;  2EWG A;  5ILJ A;  5IN8 A;  3ADZ A;  2PS7 A;  3RYE A;  2ONH A;  4GP2 A;  2Z78 A;  4FJQ A;  3IPI A;  5HNA A;  3WEF A;  5A0K A;  3AE0 A;  1HXA A;  1WL1 A;  3LMD A;  5KSX F;  3M9U A;  2J1P A;  1YYU A;  3B7L A;  3ICZ A;  1YV5 A;  2ZCO A;  2PS5 A;  3P5R A;  2Q80 A;  3N3D A;  2AZK A;  1WMW A;  3MAV A;  3AQB B;  3KRF A;  2F8Z F;  2J1O A;  4F6V A;  3CP6 A;  4NFI F;  2VF6 A;  3P8R A;  3LSN A;  2Z7H A;  2P1C A;  4LTZ A;  3G4D A;  3CKE A;  3VJB A;  3EGT A;  3QKC A;  2ZCR A;  4DEM F;  2ZEU A;  3OAC A;  4LOB A;  4RXD A;  2F8C F;  1YQ7 A;  3SDU A;  3SDR A;  5IL3 A;  5I1U A;  4KVI A;  3TFP A;  3P41 A;  3LLW A;  4E1E A;  3N0F A;  3LGK A;  1YJ4 A;  3OAC B;  1N1Z A;  3N45 F;  1FPS A;  1WL3 A;  5HN9 A;  3KRP B;  4XQT F;  3RBM A;  3WEG A;  2E91 A;  3BNY A;  4DWB A;  1YHK A;  3KRC B;  4FP4 A;  3WSB A;  1UBW A;  5DJR F;  3WCJ A;  5ILD A;  4KVW A;  2PS8 A;  1HXC A;  5IKH A;  3OAB A;  3WJN A;  3WEI A;  1N21 A;  1V4J A;  4LLS A;  4KUX A;  4MC0 A;  3WEK A;  2Z4X A;  4NKE A;  3KRO B;  4DI5 A;  2Z7I A;  5JA0 F;  4XQR F;  1RTR A;  5C05 A;  1V4I A;  4PVX F;  3VJA A;  3LK5 A;  4P0W A;  4NKF A;  4E9U A;  3G4F A;  3ZCD A;  1EZF A;  3Q1O A;  5JV0 F;  2ZCS A;  4KQU A;  2Z4W A;  3KB9 A;  5JUZ F;  3M0G A;  4LA6 A;  1HX9 A;  1WY0 A;  5DIQ F;  5HN8 A;  3ZL6 A;  1N20 A;  4KWD A;  4KVD A;  5IMN A;  4LA5 A;  1UBY A;  1WL0 A;  4WK5 A;  5E8H A;  1RQI A;  4H5C F;  4OGU A;  3Q2Z A;  4KKM A;  5DHI A;  3M02 A;  1YYQ A;  2Z4Z A;  2OPN A;  3ACW A;  5IKA A;  4H5D F;  3AQC B;  3WSA A;  5JV2 F;  2Z50 A;  3SAE A;  3NPR A;  3WCH A;  3N46 F;  3APZ A;  5A0I A;  2E8U A;  3ICM A;  1YYS A;  3PDE A;  2ZEV A;  4KVY A;  1ZW5 A;  2Q9Z A;  4XQS F;  3WE9 A;  3ACX A;  4N9U A;  4PVY F;  5ERN A;  3WCB A;  4LFV F;  4RXE A;  4NG6 A;  4MC8 A;  3Q30 A;  4JXN A;  3ACY A;  3OYR A;  4KFA A;  2E8V A;  2ZCQ A;  3DYH A;  5IMP A;  4ZQ8 A;  5B0M A;  5AEL A;  4GA3 A;  4Q23 A;  3WCA A;  3KRP A;  1VG4 A;  1PS1 A;  3LOM A;  3LZ9 A;  3ASX A;  5B0J A;  3VJE A;  2FTZ A;  3KRC A;  2F92 F;  2ZY1 A;  3ZMC A;  4DWG A;  3V1V A;  3N1V F;  3SDV A;  5DGM F;  2OPM A;  4GP1 A;  3VJC A;  3QQV A;  3Q2Q A;  1VG3 A;  3CC9 A;  4LZC A;  1VG6 A;  2PS6 A;  3NF2 A;  3UCA A;  2DH4 A;  3PYA A;  4K10 A;  1KIY A;  3N6K F;  4KPD A;  3N0G A;  2F7M F;  3KRO A;  1N1B A;  4LPH F;  3TFV A;  5ILY A;  3V1X A;  3S4J A;  3N5H F;  5B00 A;  2Q58 A;  4QPF A;  5DGS F;  2E8X A;  3TC1 A;  2E94 A;  3WCC A;  5ER8 A;  3LGZ B;  1YHM A;  5B03 A;  4JZX A;  3VJ8 A;  5DGN F;  5JV1 F;  4EA2 A;  3N5J F;  3S9V A;  4JZB A;  3WCG A;  1WKZ A;  3DYG A;  3AQ0 A;  4EA0 A;  3EFQ A;  1RQJ A;  3P8L A;  4NFK F;  5AFX A;  5IVG A;  3WCF A;  1UBX A;  1V4E A;  1DGP A;  2OGD A;  2OA6 A;  1V4K A;  4OKZ A;  3VJD A;  2PS4 A;  4RNQ A;  4OMH A;  4QXS F;  4HD1 A;  5DZ2 A;  3PKO A;  3IBA A;  2E8W A;  3WEH A;  4KK2 A;  3DYF A;  3N1W F;  2AET A;  2RAH A;  1UBV A;  4GAX A;  2J5C A;  3N49 F;  1VG7 A;  5ILZ A;  2AEL A;  4KPJ A;  4DXJ A;  5AHU B;  1DI1 A;  2E4O A;  4P0X A;  5IL8 A;  4LUU A;  3W7F A;  5B0K A;  3VJ9 A;  2ONG A;  4DZW A;  3P5P A;  5DJP F;  3ICK A;  3N3L F;  3TS7 A;  2O1O A;  5IK6 A;  3ID0 A;  1YYR A;  2FOR A;  1YHL A;  3BNX A;  4DHD A;  1N23 A;  4LLT A;  4LZ3 A;  5B01 A;  3RYW A;  1JFG A;  3KRA A;  5DHK A;  3WCD A;  3ICN A;  4UMJ A;  5ERO A;  4LFE A;  4EA1 A;  4RXA A;  2E8T A;  3WCM A;  4JXY A;  4RXC A;  4RYP A;  5DJV F;  3KRA B;  3LG5 A;  5AYP A;  1VG2 A;  1WL2 A;  1N22 A;  1JFA A;  3NRI A;  4JYX A;  2E90 A;  5E8K A;  3WCL A;  2QIS A;  3LEE A;  2AZL A;  2F9K F;  5HN7 A;  1V4H A;  5B0L A;  2Z4Y A;  3LDW A;  4LXW A;  3KRF B;  2E93 A;  4N1Z F;  2F94 F;  5IMI A;  5EAU A;  5IK0 A;  2H8O A;  4JVJ F;  5B02 A;  3SDQ A;  3WCE A;  4LIX A;  5H9D A;  2AZJ A;  1HM7 A;  1KIZ A;  4LTV A;  4OMG A;  5E8L A;  3TFN A;  3ZOU A;  3KBK A;  3LVS A;  4OKM A;  3ZMB A;  3V66 A;  5CG6 A;  3LJI A;  4P0V A;  4E9Z A;  5CG5 A;  3NPK A;  5B0I A;  1HXG A;  3RMG A;  3M00 A;  3PYB A;  5EAS A;  3WJO A;  4F62 A;  2AEK A;  4LZ0 A;  5DW7 A;  3M01 A;  1YYT A;  5ILK A;  2I19 A;  4H5E F;  4F6X A;  3WCI A; 
#chains in the Genus database with same CATH topology
 1HM4 A;  2E92 A;  3EZ3 A;  5EAT A;  4L2X F;  3MZV A;  4KQ5 A;  3WC9 A;  5ERM A;  3SDT A;  4LFG A;  2Z4V A;  4NUA A;  1N24 A;  2Q9Y A;  3OAB B;  4MC3 A;  2Z52 A;  4LPG F;  3WEJ A;  2F89 F;  2E95 A;  5IK9 A;  5A0J A;  4NFJ F;  3PH7 A;  5ILI A;  3WJK A;  5ILH A;  4KQS A;  5IM1 A;  2EWG A;  5ILJ A;  5IN8 A;  3ADZ A;  2PS7 A;  3RYE A;  2ONH A;  4GP2 A;  2Z78 A;  4FJQ A;  3IPI A;  5HNA A;  3WEF A;  5A0K A;  3AE0 A;  1HXA A;  1WL1 A;  3LMD A;  5KSX F;  3M9U A;  2J1P A;  1YYU A;  3B7L A;  3ICZ A;  1YV5 A;  2ZCO A;  2PS5 A;  3P5R A;  2Q80 A;  3N3D A;  2AZK A;  1WMW A;  3MAV A;  3AQB B;  3KRF A;  2F8Z F;  2J1O A;  4F6V A;  3CP6 A;  4NFI F;  2VF6 A;  3P8R A;  3LSN A;  2Z7H A;  2P1C A;  4LTZ A;  3G4D A;  3CKE A;  3VJB A;  3EGT A;  3QKC A;  2ZCR A;  4DEM F;  2ZEU A;  3OAC A;  4LOB A;  4RXD A;  2F8C F;  1YQ7 A;  3SDU A;  3SDR A;  5IL3 A;  5I1U A;  4KVI A;  3TFP A;  3P41 A;  3LLW A;  4E1E A;  3N0F A;  3LGK A;  1YJ4 A;  3OAC B;  1N1Z A;  3N45 F;  1FPS A;  1WL3 A;  5HN9 A;  3KRP B;  4XQT F;  3RBM A;  3WEG A;  2E91 A;  3BNY A;  4DWB A;  1YHK A;  3KRC B;  4FP4 A;  3WSB A;  1UBW A;  5DJR F;  3WCJ A;  5ILD A;  4KVW A;  2PS8 A;  1HXC A;  5IKH A;  3OAB A;  3WJN A;  3WEI A;  1N21 A;  1V4J A;  4LLS A;  4KUX A;  4MC0 A;  3WEK A;  2Z4X A;  4NKE A;  3KRO B;  4DI5 A;  2Z7I A;  5JA0 F;  4XQR F;  1RTR A;  5C05 A;  1V4I A;  4PVX F;  3VJA A;  3LK5 A;  4P0W A;  4NKF A;  4E9U A;  3G4F A;  3ZCD A;  1EZF A;  3Q1O A;  5JV0 F;  2ZCS A;  4KQU A;  2Z4W A;  3KB9 A;  5JUZ F;  3M0G A;  4LA6 A;  1HX9 A;  1WY0 A;  5DIQ F;  5HN8 A;  3ZL6 A;  1N20 A;  4KWD A;  4KVD A;  5IMN A;  4LA5 A;  1UBY A;  1WL0 A;  4WK5 A;  5E8H A;  1RQI A;  4H5C F;  4OGU A;  3Q2Z A;  4KKM A;  5DHI A;  3M02 A;  1YYQ A;  2Z4Z A;  2OPN A;  3ACW A;  5IKA A;  4H5D F;  3AQC B;  3WSA A;  5JV2 F;  2Z50 A;  3SAE A;  3NPR A;  3WCH A;  3N46 F;  3APZ A;  5A0I A;  2E8U A;  3ICM A;  1YYS A;  3PDE A;  2ZEV A;  4KVY A;  1ZW5 A;  2Q9Z A;  4XQS F;  3WE9 A;  3ACX A;  4N9U A;  4PVY F;  5ERN A;  3WCB A;  4LFV F;  4RXE A;  4NG6 A;  4MC8 A;  3Q30 A;  4JXN A;  3ACY A;  3OYR A;  4KFA A;  2E8V A;  2ZCQ A;  3DYH A;  5IMP A;  4ZQ8 A;  5B0M A;  5AEL A;  4GA3 A;  4Q23 A;  3WCA A;  3KRP A;  1VG4 A;  1PS1 A;  3LOM A;  3LZ9 A;  3ASX A;  5B0J A;  3VJE A;  2FTZ A;  3KRC A;  2F92 F;  2ZY1 A;  3ZMC A;  4DWG A;  3V1V A;  3N1V F;  3SDV A;  5DGM F;  2OPM A;  4GP1 A;  3VJC A;  3QQV A;  3Q2Q A;  1VG3 A;  3CC9 A;  4LZC A;  1VG6 A;  2PS6 A;  3NF2 A;  3UCA A;  2DH4 A;  3PYA A;  4K10 A;  1KIY A;  3N6K F;  4KPD A;  3N0G A;  2F7M F;  3KRO A;  1N1B A;  4LPH F;  3TFV A;  5ILY A;  3V1X A;  3S4J A;  3N5H F;  5B00 A;  2Q58 A;  4QPF A;  5DGS F;  2E8X A;  3TC1 A;  2E94 A;  3WCC A;  5ER8 A;  3LGZ B;  1YHM A;  5B03 A;  4JZX A;  3VJ8 A;  5DGN F;  5JV1 F;  4EA2 A;  3N5J F;  3S9V A;  4JZB A;  3WCG A;  1WKZ A;  3DYG A;  3AQ0 A;  4EA0 A;  3EFQ A;  1RQJ A;  3P8L A;  4NFK F;  5AFX A;  5IVG A;  3WCF A;  1UBX A;  1V4E A;  1DGP A;  2OGD A;  2OA6 A;  1V4K A;  4OKZ A;  3VJD A;  2PS4 A;  4RNQ A;  4OMH A;  4QXS F;  4HD1 A;  5DZ2 A;  3PKO A;  3IBA A;  2E8W A;  3WEH A;  4KK2 A;  3DYF A;  3N1W F;  2AET A;  2RAH A;  1UBV A;  4GAX A;  2J5C A;  3N49 F;  1VG7 A;  5ILZ A;  2AEL A;  4KPJ A;  4DXJ A;  5AHU B;  1DI1 A;  2E4O A;  4P0X A;  5IL8 A;  4LUU A;  3W7F A;  5B0K A;  3VJ9 A;  2ONG A;  4DZW A;  3P5P A;  5DJP F;  3ICK A;  3N3L F;  3TS7 A;  2O1O A;  5IK6 A;  3ID0 A;  1YYR A;  2FOR A;  1YHL A;  3BNX A;  4DHD A;  1N23 A;  4LLT A;  4LZ3 A;  5B01 A;  3RYW A;  1JFG A;  3KRA A;  5DHK A;  3WCD A;  3ICN A;  4UMJ A;  5ERO A;  4LFE A;  4EA1 A;  4RXA A;  2E8T A;  3WCM A;  4JXY A;  4RXC A;  4RYP A;  5DJV F;  3KRA B;  3LG5 A;  5AYP A;  1VG2 A;  1WL2 A;  1N22 A;  1JFA A;  3NRI A;  4JYX A;  2E90 A;  5E8K A;  3WCL A;  2QIS A;  3LEE A;  2AZL A;  2F9K F;  5HN7 A;  1V4H A;  5B0L A;  2Z4Y A;  3LDW A;  4LXW A;  3KRF B;  2E93 A;  4N1Z F;  2F94 F;  5IMI A;  5EAU A;  5IK0 A;  2H8O A;  4JVJ F;  5B02 A;  3SDQ A;  3WCE A;  4LIX A;  5H9D A;  2AZJ A;  1HM7 A;  1KIZ A;  4LTV A;  4OMG A;  5E8L A;  3TFN A;  3ZOU A;  3KBK A;  3LVS A;  4OKM A;  3ZMB A;  3V66 A;  5CG6 A;  3LJI A;  4P0V A;  4E9Z A;  5CG5 A;  3NPK A;  5B0I A;  1HXG A;  3RMG A;  3M00 A;  3PYB A;  5EAS A;  3WJO A;  4F62 A;  2AEK A;  4LZ0 A;  5DW7 A;  3M01 A;  1YYT A;  5ILK A;  2I19 A;  4H5E F;  4F6X A;  3WCI A; 
#chains in the Genus database with same CATH homology
 1HM4 A;  2E92 A;  3EZ3 A;  5EAT A;  4L2X F;  3MZV A;  4KQ5 A;  3WC9 A;  5ERM A;  3SDT A;  4LFG A;  2Z4V A;  4NUA A;  1N24 A;  2Q9Y A;  3OAB B;  4MC3 A;  2Z52 A;  4LPG F;  3WEJ A;  2F89 F;  2E95 A;  5IK9 A;  5A0J A;  4NFJ F;  3PH7 A;  5ILI A;  3WJK A;  5ILH A;  4KQS A;  5IM1 A;  2EWG A;  5ILJ A;  5IN8 A;  3ADZ A;  2PS7 A;  3RYE A;  2ONH A;  4GP2 A;  2Z78 A;  4FJQ A;  3IPI A;  5HNA A;  3WEF A;  5A0K A;  3AE0 A;  1HXA A;  1WL1 A;  3LMD A;  5KSX F;  3M9U A;  2J1P A;  1YYU A;  3B7L A;  3ICZ A;  1YV5 A;  2ZCO A;  2PS5 A;  3P5R A;  2Q80 A;  3N3D A;  2AZK A;  1WMW A;  3MAV A;  3AQB B;  3KRF A;  2F8Z F;  2J1O A;  4F6V A;  3CP6 A;  4NFI F;  2VF6 A;  3P8R A;  3LSN A;  2Z7H A;  2P1C A;  4LTZ A;  3G4D A;  3CKE A;  3VJB A;  3EGT A;  3QKC A;  2ZCR A;  4DEM F;  2ZEU A;  3OAC A;  4LOB A;  4RXD A;  2F8C F;  1YQ7 A;  3SDU A;  3SDR A;  5IL3 A;  5I1U A;  4KVI A;  3TFP A;  3P41 A;  3LLW A;  4E1E A;  3N0F A;  3LGK A;  1YJ4 A;  3OAC B;  1N1Z A;  3N45 F;  1FPS A;  1WL3 A;  5HN9 A;  3KRP B;  4XQT F;  3RBM A;  3WEG A;  2E91 A;  3BNY A;  4DWB A;  1YHK A;  3KRC B;  4FP4 A;  3WSB A;  1UBW A;  5DJR F;  3WCJ A;  5ILD A;  4KVW A;  2PS8 A;  1HXC A;  5IKH A;  3OAB A;  3WJN A;  3WEI A;  1N21 A;  1V4J A;  4LLS A;  4KUX A;  4MC0 A;  3WEK A;  2Z4X A;  4NKE A;  3KRO B;  4DI5 A;  2Z7I A;  5JA0 F;  4XQR F;  1RTR A;  5C05 A;  1V4I A;  4PVX F;  3VJA A;  3LK5 A;  4P0W A;  4NKF A;  4E9U A;  3G4F A;  3ZCD A;  1EZF A;  3Q1O A;  5JV0 F;  2ZCS A;  4KQU A;  2Z4W A;  3KB9 A;  5JUZ F;  3M0G A;  4LA6 A;  1HX9 A;  1WY0 A;  5DIQ F;  5HN8 A;  3ZL6 A;  1N20 A;  4KWD A;  4KVD A;  5IMN A;  4LA5 A;  1UBY A;  1WL0 A;  4WK5 A;  5E8H A;  1RQI A;  4H5C F;  4OGU A;  3Q2Z A;  4KKM A;  5DHI A;  3M02 A;  1YYQ A;  2Z4Z A;  2OPN A;  3ACW A;  5IKA A;  4H5D F;  3AQC B;  3WSA A;  5JV2 F;  2Z50 A;  3SAE A;  3NPR A;  3WCH A;  3N46 F;  3APZ A;  5A0I A;  2E8U A;  3ICM A;  1YYS A;  3PDE A;  2ZEV A;  4KVY A;  1ZW5 A;  2Q9Z A;  4XQS F;  3WE9 A;  3ACX A;  4N9U A;  4PVY F;  5ERN A;  3WCB A;  4LFV F;  4RXE A;  4NG6 A;  4MC8 A;  3Q30 A;  4JXN A;  3ACY A;  3OYR A;  4KFA A;  2E8V A;  2ZCQ A;  3DYH A;  5IMP A;  4ZQ8 A;  5B0M A;  5AEL A;  4GA3 A;  4Q23 A;  3WCA A;  3KRP A;  1VG4 A;  1PS1 A;  3LOM A;  3LZ9 A;  3ASX A;  5B0J A;  3VJE A;  2FTZ A;  3KRC A;  2F92 F;  2ZY1 A;  3ZMC A;  4DWG A;  3V1V A;  3N1V F;  3SDV A;  5DGM F;  2OPM A;  4GP1 A;  3VJC A;  3QQV A;  3Q2Q A;  1VG3 A;  3CC9 A;  4LZC A;  1VG6 A;  2PS6 A;  3NF2 A;  3UCA A;  2DH4 A;  3PYA A;  4K10 A;  1KIY A;  3N6K F;  4KPD A;  3N0G A;  2F7M F;  3KRO A;  1N1B A;  4LPH F;  3TFV A;  5ILY A;  3V1X A;  3S4J A;  3N5H F;  5B00 A;  2Q58 A;  4QPF A;  5DGS F;  2E8X A;  3TC1 A;  2E94 A;  3WCC A;  5ER8 A;  3LGZ B;  1YHM A;  5B03 A;  4JZX A;  3VJ8 A;  5DGN F;  5JV1 F;  4EA2 A;  3N5J F;  3S9V A;  4JZB A;  3WCG A;  1WKZ A;  3DYG A;  3AQ0 A;  4EA0 A;  3EFQ A;  1RQJ A;  3P8L A;  4NFK F;  5AFX A;  5IVG A;  3WCF A;  1UBX A;  1V4E A;  1DGP A;  2OGD A;  2OA6 A;  1V4K A;  4OKZ A;  3VJD A;  2PS4 A;  4RNQ A;  4OMH A;  4QXS F;  4HD1 A;  5DZ2 A;  3PKO A;  3IBA A;  2E8W A;  3WEH A;  4KK2 A;  3DYF A;  3N1W F;  2AET A;  2RAH A;  1UBV A;  4GAX A;  2J5C A;  3N49 F;  1VG7 A;  5ILZ A;  2AEL A;  4KPJ A;  4DXJ A;  5AHU B;  1DI1 A;  2E4O A;  4P0X A;  5IL8 A;  4LUU A;  3W7F A;  5B0K A;  3VJ9 A;  2ONG A;  4DZW A;  3P5P A;  5DJP F;  3ICK A;  3N3L F;  3TS7 A;  2O1O A;  5IK6 A;  3ID0 A;  1YYR A;  2FOR A;  1YHL A;  3BNX A;  4DHD A;  1N23 A;  4LLT A;  4LZ3 A;  5B01 A;  3RYW A;  1JFG A;  3KRA A;  5DHK A;  3WCD A;  3ICN A;  4UMJ A;  5ERO A;  4LFE A;  4EA1 A;  4RXA A;  2E8T A;  3WCM A;  4JXY A;  4RXC A;  4RYP A;  5DJV F;  3KRA B;  3LG5 A;  5AYP A;  1VG2 A;  1WL2 A;  1N22 A;  1JFA A;  3NRI A;  4JYX A;  2E90 A;  5E8K A;  3WCL A;  2QIS A;  3LEE A;  2AZL A;  2F9K F;  5HN7 A;  1V4H A;  5B0L A;  2Z4Y A;  3LDW A;  4LXW A;  3KRF B;  2E93 A;  4N1Z F;  2F94 F;  5IMI A;  5EAU A;  5IK0 A;  2H8O A;  4JVJ F;  5B02 A;  3SDQ A;  3WCE A;  4LIX A;  5H9D A;  2AZJ A;  1HM7 A;  1KIZ A;  4LTV A;  4OMG A;  5E8L A;  3TFN A;  3ZOU A;  3KBK A;  3LVS A;  4OKM A;  3ZMB A;  3V66 A;  5CG6 A;  3LJI A;  4P0V A;  4E9Z A;  5CG5 A;  3NPK A;  5B0I A;  1HXG A;  3RMG A;  3M00 A;  3PYB A;  5EAS A;  3WJO A;  4F62 A;  2AEK A;  4LZ0 A;  5DW7 A;  3M01 A;  1YYT A;  5ILK A;  2I19 A;  4H5E F;  4F6X A;  3WCI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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