4KFAA

Crystal structure of human farnesyl pyrophosphate synthase (t201a mutant) complexed with mg and zoledronate
Total Genus 131
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
131
sequence length
342
structure length
338
Chain Sequence
VYAQEKQDFVQHFSQIVRVLTEHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKAAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
molecule keywords Farnesyl pyrophosphate synthase
publication title Crystal structure of human farnesyl pyrophosphate synthase (t201a mutant) complexed with mg and zoledronate
rcsb
source organism Homo sapiens
total genus 131
structure length 338
sequence length 342
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2013-04-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4kfaA00
4XQTF 5H9DA 4LTZA 3KRCB 2ZCSA 5IK9A 2FTZA 1VG3A 1DI1A 4NG6A 3NF2A 4H5DF 3WJOA 5HN9A 2PS6A 4DI5A 5A0JA 4KUXA 4F6VA 1WMWA 3WSBA 3CKEA 1KIZA 5E8KA 3ICMA 3G4FA 2AEKA 3RYWA 4H5EF 3VJCA 4LFGA 3V1VA 3TFPA 2Z7IA 3WCEA 3KB9A 3S9VA 5DJRF 4GAXA 1WL3A 4ZQ8A 3V1XA 1UBVA 3WCHA 5ILZA 2E91A 4MC8A 5JV2F 1N1ZA 4EA2A 1PS1A 4DXJA 4KWDA 5E8LA 3RBMA 5ILDA 1FPSA 4KK2A 3WCMA 5B0LA 4LZCA 4QXSF 5B02A 3LK5A 4DEMF 2ONGA 3AQBB 2Z4YA 3WCIA 3WCJA 1V4HA 1RQIA 2E90A 3WCDA 3LGZB 3KRAA 4MC3A 4KVDA 3WCCA 3LDWA 2ZY1A 3BNYA 2OGDA 5AELA 4JZBA 3MAVA 3RMGA 4JYXA 3ICZA 1V4JA 3P41A 3DYFA 2E8VA 3CP6A 3SDVA 2ONHA 3P5RA 2Z4ZA 2J1PA 3Q2QA 5IL3A 4OMHA 2F8CF 3LEEA 3ACXA 4LLTA 3B7LA 3NRIA 5I1UA 2F9KF 1N23A 3KRPA 5AFXA 2AZJA 2Z4XA 3M00A 3ZMBA 3ZL6A 3LGKA 4FJQA 3Q30A 1HM4A 2AELA 5EASA 4KVWA 2E4OA 2DH4A 1YHMA 4KQSA 3Q1OA 1DGPA 1HXAA 4P0VA 5ERNA 5ILHA 4LPGF 2O1OA 2Z52A 3SDRA 2Z4WA 3P8RA 4NUAA 4PVYF 4LLSA 5IN8A 5JA0F 2PS5A 4OGUA 3S4JA 4LOBA 2FORA 1YYUA 4LIXA 5IKAA 1HXCA 3PYBA 3WCBA 3AQ0A 3N0FA 5B0IA 1YHLA 3N45F 3N5HF 3NPRA 3WEFA 3WC9A 5DJVF 1HM7A 4LZ3A 4RXDA 1UBXA 2AZKA 3TFVA 4PVXF 2Z50A 3ICKA 3EFQA 5IVGA 4LA6A 3APZA 3PDEA 2EWGA 1UBYA 3N1VF 5ILYA 2Q58A 4NKFA 5JUZF 5JV1F 3EZ3A 5DJPF 4GA3A 5A0IA 3WCGA 2ZEUA 4KPJA 5C05A 3G4DA 5DGMF 3M9UA 3UCAA 3VJAA 3LOMA 3IBAA 3WCFA 5IMIA 5IM1A 5KSXF 3LSNA 2F92F 5DGSF 3AE0A 1YYTA 3LG5A 4H5CF 1WKZA 1N20A 4LXWA 4K10A 4KVYA 3P8LA 4E1EA 2OPNA 2Z7HA 2VF6A 1WL0A 1YQ7A 4RNQA 5HNAA 3WEKA 1V4KA 3ID0A 4RXAA 1VG7A 1WL2A 4KFAA 4KVIA 2PS4A 5AHUB 3SDQA 3KRAB 2E8XA 2F94F 5B0KA 2Q9YA 3ASXA 1N21A 4OMGA 2AETA 3M01A 3WSAA 3DYGA 3N3DA 1ZW5A 4OKZA 1YJ4A 3N49F 1WY0A 3WE9A 3ACWA 5HN7A 4E9ZA 3WJNA 4DWBA 3KRFB 2F89F 4KQUA 5DW7A 2ZCRA 5B0MA 5CG6A 3OACB 3SAEA 5ILIA 2F8ZF 5IMNA 2OA6A 3N1WF 4KKMA 3KROA 3LLWA 1KIYA 4UMJA 4GP1A 5AYPA 2AZLA 4XQSF 2J1OA 2E8TA 5IK0A 3KRPB 5DHIA 3WEIA 1N24A 1VG2A 2P1CA 4LA5A 3IPIA 5B0JA 4DWGA 2I19A 3OABB 3ZMCA 1RQJA 2E95A 5ER8A 4NKEA 4XQRF 3WEHA 3KRCA 3KBKA 3ADZA 5B00A 5HN8A 4LTVA 2Q80A 2ZCQA 1HXGA 4LFVF 4N1ZF 1YYQA 2E8WA 4E9UA 5IKHA 2QISA 4KPDA 5DGNF 5E8HA 1YHKA 5CG5A 5A0KA 4LUUA 3ZOUA 2ZEVA 5JV0F 4NFJF 1VG6A 2E94A 4GP2A 3PH7A 4DZWA 1V4EA 4F62A 4LFEA 3QKCA 3WJKA 4KQ5A 4NFKF 3DYHA 3V66A 2E92A 4FP4A 5EAUA 4RXEA 4HD1A 4QPFA 1YYSA 3N6KF 4JXYA 1JFGA 3SDUA 3VJ8A 1JFAA 2Z78A 3ICNA 5B01A 5IMPA 3LZ9A 3WEGA 1YV5A 3ACYA 3Q2ZA 5DZ2A 2PS8A 1RTRA 3TC1A 4RYPA 2OPMA 4JXNA 1UBWA 3CC9A 4NFIF 3WCAA 1EZFA 2Q9ZA 4LPHF 4DHDA 3TFNA 3EGTA 3M02A 3W7FA 5ILJA 1YYRA 3VJBA 3LVSA 3WEJA 5ERMA 4Q23A 3RYEA 3BNXA 4WK5A 4L2XF 3WCLA 4P0WA 5EATA 3SDTA 4F6XA 3OYRA 1VG4A 3VJEA 3N0GA 3NPKA 3QQVA 1HX9A 2E8UA 5IK6A 4JZXA 4MC0A 2RAHA 3LMDA 3N5JF 2E93A 2Z4VA 2F7MF 4RXCA 3PYAA 3AQCB 4OKMA 3N46F 3TS7A 1V4IA 3VJ9A 5EROA 3KRFA 2H8OA 2J5CA 3KROB 3OACA 2PS7A 5ILKA 4EA0A 5DIQF 5B03A 4P0XA 1N1BA 4JVJF 3MZVA 4LZ0A 3ZCDA 3LJIA 4EA1A 5DHKA 3P5PA 4N9UA 3PKOA 1WL1A 5IL8A 3OABA 3VJDA 1N22A 3M0GA 2ZCOA 3N3LF
chains in the Genus database with same CATH superfamily
4XQTF 5H9DA 4LTZA 3KRCB 2ZCSA 5IK9A 2FTZA 1VG3A 1DI1A 4NG6A 3NF2A 4H5DF 3WJOA 5HN9A 2PS6A 4DI5A 5A0JA 4KUXA 4F6VA 1WMWA 3WSBA 3CKEA 1KIZA 5E8KA 3ICMA 3G4FA 2AEKA 3RYWA 4H5EF 3VJCA 4LFGA 3V1VA 3TFPA 2Z7IA 3WCEA 3KB9A 3S9VA 5DJRF 4GAXA 1WL3A 4ZQ8A 3V1XA 1UBVA 3WCHA 5ILZA 2E91A 4MC8A 5JV2F 1N1ZA 4EA2A 1PS1A 4DXJA 4KWDA 5E8LA 3RBMA 5ILDA 1FPSA 4KK2A 3WCMA 5B0LA 4LZCA 4QXSF 5B02A 3LK5A 4DEMF 2ONGA 3AQBB 2Z4YA 3WCIA 3WCJA 1V4HA 1RQIA 2E90A 3WCDA 3LGZB 3KRAA 4MC3A 4KVDA 3WCCA 3LDWA 2ZY1A 3BNYA 2OGDA 5AELA 4JZBA 3MAVA 3RMGA 4JYXA 3ICZA 1V4JA 3P41A 3DYFA 2E8VA 3CP6A 3SDVA 2ONHA 3P5RA 2Z4ZA 2J1PA 3Q2QA 5IL3A 4OMHA 2F8CF 3LEEA 3ACXA 4LLTA 3B7LA 3NRIA 5I1UA 2F9KF 1N23A 3KRPA 5AFXA 2AZJA 2Z4XA 3M00A 3ZMBA 3ZL6A 3LGKA 4FJQA 3Q30A 1HM4A 2AELA 5EASA 4KVWA 2E4OA 2DH4A 1YHMA 4KQSA 3Q1OA 1DGPA 1HXAA 4P0VA 5ERNA 5ILHA 4LPGF 2O1OA 2Z52A 3SDRA 2Z4WA 3P8RA 4NUAA 4PVYF 4LLSA 5IN8A 5JA0F 2PS5A 4OGUA 3S4JA 4LOBA 2FORA 1YYUA 4LIXA 5IKAA 1HXCA 3PYBA 3WCBA 3AQ0A 3N0FA 5B0IA 1YHLA 3N45F 3N5HF 3NPRA 3WEFA 3WC9A 5DJVF 1HM7A 4LZ3A 4RXDA 1UBXA 2AZKA 3TFVA 4PVXF 2Z50A 3ICKA 3EFQA 5IVGA 4LA6A 3APZA 3PDEA 2EWGA 1UBYA 3N1VF 5ILYA 2Q58A 4NKFA 5JUZF 5JV1F 3EZ3A 5DJPF 4GA3A 5A0IA 3WCGA 2ZEUA 4KPJA 5C05A 3G4DA 5DGMF 3M9UA 3UCAA 3VJAA 3LOMA 3IBAA 3WCFA 5IMIA 5IM1A 5KSXF 3LSNA 2F92F 5DGSF 3AE0A 1YYTA 3LG5A 4H5CF 1WKZA 1N20A 4LXWA 4K10A 4KVYA 3P8LA 4E1EA 2OPNA 2Z7HA 2VF6A 1WL0A 1YQ7A 4RNQA 5HNAA 3WEKA 1V4KA 3ID0A 4RXAA 1VG7A 1WL2A 4KFAA 4KVIA 2PS4A 5AHUB 3SDQA 3KRAB 2E8XA 2F94F 5B0KA 2Q9YA 3ASXA 1N21A 4OMGA 2AETA 3M01A 3WSAA 3DYGA 3N3DA 1ZW5A 4OKZA 1YJ4A 3N49F 1WY0A 3WE9A 3ACWA 5HN7A 4E9ZA 3WJNA 4DWBA 3KRFB 2F89F 4KQUA 5DW7A 2ZCRA 5B0MA 5CG6A 3OACB 3SAEA 5ILIA 2F8ZF 5IMNA 2OA6A 3N1WF 4KKMA 3KROA 3LLWA 1KIYA 4UMJA 4GP1A 5AYPA 2AZLA 4XQSF 2J1OA 2E8TA 5IK0A 3KRPB 5DHIA 3WEIA 1N24A 1VG2A 2P1CA 4LA5A 3IPIA 5B0JA 4DWGA 2I19A 3OABB 3ZMCA 1RQJA 2E95A 5ER8A 4NKEA 4XQRF 3WEHA 3KRCA 3KBKA 3ADZA 5B00A 5HN8A 4LTVA 2Q80A 2ZCQA 1HXGA 4LFVF 4N1ZF 1YYQA 2E8WA 4E9UA 5IKHA 2QISA 4KPDA 5DGNF 5E8HA 1YHKA 5CG5A 5A0KA 4LUUA 3ZOUA 2ZEVA 5JV0F 4NFJF 1VG6A 2E94A 4GP2A 3PH7A 4DZWA 1V4EA 4F62A 4LFEA 3QKCA 3WJKA 4KQ5A 4NFKF 3DYHA 3V66A 2E92A 4FP4A 5EAUA 4RXEA 4HD1A 4QPFA 1YYSA 3N6KF 4JXYA 1JFGA 3SDUA 3VJ8A 1JFAA 2Z78A 3ICNA 5B01A 5IMPA 3LZ9A 3WEGA 1YV5A 3ACYA 3Q2ZA 5DZ2A 2PS8A 1RTRA 3TC1A 4RYPA 2OPMA 4JXNA 1UBWA 3CC9A 4NFIF 3WCAA 1EZFA 2Q9ZA 4LPHF 4DHDA 3TFNA 3EGTA 3M02A 3W7FA 5ILJA 1YYRA 3VJBA 3LVSA 3WEJA 5ERMA 4Q23A 3RYEA 3BNXA 4WK5A 4L2XF 3WCLA 4P0WA 5EATA 3SDTA 4F6XA 3OYRA 1VG4A 3VJEA 3N0GA 3NPKA 3QQVA 1HX9A 2E8UA 5IK6A 4JZXA 4MC0A 2RAHA 3LMDA 3N5JF 2E93A 2Z4VA 2F7MF 4RXCA 3PYAA 3AQCB 4OKMA 3N46F 3TS7A 1V4IA 3VJ9A 5EROA 3KRFA 2H8OA 2J5CA 3KROB 3OACA 2PS7A 5ILKA 4EA0A 5DIQF 5B03A 4P0XA 1N1BA 4JVJF 3MZVA 4LZ0A 3ZCDA 3LJIA 4EA1A 5DHKA 3P5PA 4N9UA 3PKOA 1WL1A 5IL8A 3OABA 3VJDA 1N22A 3M0GA 2ZCOA 3N3LF
chains in the Genus database with same CATH topology
4XQTF 5H9DA 4LTZA 3KRCB 2ZCSA 5IK9A 2FTZA 1VG3A 1DI1A 4NG6A 3NF2A 4H5DF 3WJOA 5HN9A 2PS6A 4DI5A 5A0JA 4KUXA 4F6VA 1WMWA 3WSBA 3CKEA 1KIZA 5E8KA 3ICMA 3G4FA 2AEKA 3RYWA 4H5EF 3VJCA 4LFGA 3V1VA 3TFPA 2Z7IA 3WCEA 3KB9A 3S9VA 5DJRF 4GAXA 1WL3A 4ZQ8A 3V1XA 1UBVA 3WCHA 5ILZA 2E91A 4MC8A 5JV2F 1N1ZA 4EA2A 1PS1A 4DXJA 4KWDA 5E8LA 3RBMA 5ILDA 1FPSA 4KK2A 3WCMA 5B0LA 4LZCA 4QXSF 5B02A 3LK5A 4DEMF 2ONGA 3AQBB 2Z4YA 3WCIA 3WCJA 1V4HA 1RQIA 2E90A 3WCDA 3LGZB 3KRAA 4MC3A 4KVDA 3WCCA 3LDWA 2ZY1A 3BNYA 2OGDA 5AELA 4JZBA 3MAVA 3RMGA 4JYXA 3ICZA 1V4JA 3P41A 3DYFA 2E8VA 3CP6A 3SDVA 2ONHA 3P5RA 2Z4ZA 2J1PA 3Q2QA 5IL3A 4OMHA 2F8CF 3LEEA 3ACXA 4LLTA 3B7LA 3NRIA 5I1UA 2F9KF 1N23A 3KRPA 5AFXA 2AZJA 2Z4XA 3M00A 3ZMBA 3ZL6A 3LGKA 4FJQA 3Q30A 1HM4A 2AELA 5EASA 4KVWA 2E4OA 2DH4A 1YHMA 4KQSA 3Q1OA 1DGPA 1HXAA 4P0VA 5ERNA 5ILHA 4LPGF 2O1OA 2Z52A 3SDRA 2Z4WA 3P8RA 4NUAA 4PVYF 4LLSA 5IN8A 5JA0F 2PS5A 4OGUA 3S4JA 4LOBA 2FORA 1YYUA 4LIXA 5IKAA 1HXCA 3PYBA 3WCBA 3AQ0A 3N0FA 5B0IA 1YHLA 3N45F 3N5HF 3NPRA 3WEFA 3WC9A 5DJVF 1HM7A 4LZ3A 4RXDA 1UBXA 2AZKA 3TFVA 4PVXF 2Z50A 3ICKA 3EFQA 5IVGA 4LA6A 3APZA 3PDEA 2EWGA 1UBYA 3N1VF 5ILYA 2Q58A 4NKFA 5JUZF 5JV1F 3EZ3A 5DJPF 4GA3A 5A0IA 3WCGA 2ZEUA 4KPJA 5C05A 3G4DA 5DGMF 3M9UA 3UCAA 3VJAA 3LOMA 3IBAA 3WCFA 5IMIA 5IM1A 5KSXF 3LSNA 2F92F 5DGSF 3AE0A 1YYTA 3LG5A 4H5CF 1WKZA 1N20A 4LXWA 4K10A 4KVYA 3P8LA 4E1EA 2OPNA 2Z7HA 2VF6A 1WL0A 1YQ7A 4RNQA 5HNAA 3WEKA 1V4KA 3ID0A 4RXAA 1VG7A 1WL2A 4KFAA 4KVIA 2PS4A 5AHUB 3SDQA 3KRAB 2E8XA 2F94F 5B0KA 2Q9YA 3ASXA 1N21A 4OMGA 2AETA 3M01A 3WSAA 3DYGA 3N3DA 1ZW5A 4OKZA 1YJ4A 3N49F 1WY0A 3WE9A 3ACWA 5HN7A 4E9ZA 3WJNA 4DWBA 3KRFB 2F89F 4KQUA 5DW7A 2ZCRA 5B0MA 5CG6A 3OACB 3SAEA 5ILIA 2F8ZF 5IMNA 2OA6A 3N1WF 4KKMA 3KROA 3LLWA 1KIYA 4UMJA 4GP1A 5AYPA 2AZLA 4XQSF 2J1OA 2E8TA 5IK0A 3KRPB 5DHIA 3WEIA 1N24A 1VG2A 2P1CA 4LA5A 3IPIA 5B0JA 4DWGA 2I19A 3OABB 3ZMCA 1RQJA 2E95A 5ER8A 4NKEA 4XQRF 3WEHA 3KRCA 3KBKA 3ADZA 5B00A 5HN8A 4LTVA 2Q80A 2ZCQA 1HXGA 4LFVF 4N1ZF 1YYQA 2E8WA 4E9UA 5IKHA 2QISA 4KPDA 5DGNF 5E8HA 1YHKA 5CG5A 5A0KA 4LUUA 3ZOUA 2ZEVA 5JV0F 4NFJF 1VG6A 2E94A 4GP2A 3PH7A 4DZWA 1V4EA 4F62A 4LFEA 3QKCA 3WJKA 4KQ5A 4NFKF 3DYHA 3V66A 2E92A 4FP4A 5EAUA 4RXEA 4HD1A 4QPFA 1YYSA 3N6KF 4JXYA 1JFGA 3SDUA 3VJ8A 1JFAA 2Z78A 3ICNA 5B01A 5IMPA 3LZ9A 3WEGA 1YV5A 3ACYA 3Q2ZA 5DZ2A 2PS8A 1RTRA 3TC1A 4RYPA 2OPMA 4JXNA 1UBWA 3CC9A 4NFIF 3WCAA 1EZFA 2Q9ZA 4LPHF 4DHDA 3TFNA 3EGTA 3M02A 3W7FA 5ILJA 1YYRA 3VJBA 3LVSA 3WEJA 5ERMA 4Q23A 3RYEA 3BNXA 4WK5A 4L2XF 3WCLA 4P0WA 5EATA 3SDTA 4F6XA 3OYRA 1VG4A 3VJEA 3N0GA 3NPKA 3QQVA 1HX9A 2E8UA 5IK6A 4JZXA 4MC0A 2RAHA 3LMDA 3N5JF 2E93A 2Z4VA 2F7MF 4RXCA 3PYAA 3AQCB 4OKMA 3N46F 3TS7A 1V4IA 3VJ9A 5EROA 3KRFA 2H8OA 2J5CA 3KROB 3OACA 2PS7A 5ILKA 4EA0A 5DIQF 5B03A 4P0XA 1N1BA 4JVJF 3MZVA 4LZ0A 3ZCDA 3LJIA 4EA1A 5DHKA 3P5PA 4N9UA 3PKOA 1WL1A 5IL8A 3OABA 3VJDA 1N22A 3M0GA 2ZCOA 3N3LF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XQT F;  5H9D A;  4LTZ A;  3KRC B;  2ZCS A;  5IK9 A;  2FTZ A;  1VG3 A;  1DI1 A;  4NG6 A;  3NF2 A;  4H5D F;  3WJO A;  5HN9 A;  2PS6 A;  4DI5 A;  5A0J A;  4KUX A;  4F6V A;  1WMW A;  3WSB A;  3CKE A;  1KIZ A;  5E8K A;  3ICM A;  3G4F A;  2AEK A;  3RYW A;  4H5E F;  3VJC A;  4LFG A;  3V1V A;  3TFP A;  2Z7I A;  3WCE A;  3KB9 A;  3S9V A;  5DJR F;  4GAX A;  1WL3 A;  4ZQ8 A;  3V1X A;  1UBV A;  3WCH A;  5ILZ A;  2E91 A;  4MC8 A;  5JV2 F;  1N1Z A;  4EA2 A;  1PS1 A;  4DXJ A;  4KWD A;  5E8L A;  3RBM A;  5ILD A;  1FPS A;  4KK2 A;  3WCM A;  5B0L A;  4LZC A;  4QXS F;  5B02 A;  3LK5 A;  4DEM F;  2ONG A;  3AQB B;  2Z4Y A;  3WCI A;  3WCJ A;  1V4H A;  1RQI A;  2E90 A;  3WCD A;  3LGZ B;  3KRA A;  4MC3 A;  4KVD A;  3WCC A;  3LDW A;  2ZY1 A;  3BNY A;  2OGD A;  5AEL A;  4JZB A;  3MAV A;  3RMG A;  4JYX A;  3ICZ A;  1V4J A;  3P41 A;  3DYF A;  2E8V A;  3CP6 A;  3SDV A;  2ONH A;  3P5R A;  2Z4Z A;  2J1P A;  3Q2Q A;  5IL3 A;  4OMH A;  2F8C F;  3LEE A;  3ACX A;  4LLT A;  3B7L A;  3NRI A;  5I1U A;  2F9K F;  1N23 A;  3KRP A;  5AFX A;  2AZJ A;  2Z4X A;  3M00 A;  3ZMB A;  3ZL6 A;  3LGK A;  4FJQ A;  3Q30 A;  1HM4 A;  2AEL A;  5EAS A;  4KVW A;  2E4O A;  2DH4 A;  1YHM A;  4KQS A;  3Q1O A;  1DGP A;  1HXA A;  4P0V A;  5ERN A;  5ILH A;  4LPG F;  2O1O A;  2Z52 A;  3SDR A;  2Z4W A;  3P8R A;  4NUA A;  4PVY F;  4LLS A;  5IN8 A;  5JA0 F;  2PS5 A;  4OGU A;  3S4J A;  4LOB A;  2FOR A;  1YYU A;  4LIX A;  5IKA A;  1HXC A;  3PYB A;  3WCB A;  3AQ0 A;  3N0F A;  5B0I A;  1YHL A;  3N45 F;  3N5H F;  3NPR A;  3WEF A;  3WC9 A;  5DJV F;  1HM7 A;  4LZ3 A;  4RXD A;  1UBX A;  2AZK A;  3TFV A;  4PVX F;  2Z50 A;  3ICK A;  3EFQ A;  5IVG A;  4LA6 A;  3APZ A;  3PDE A;  2EWG A;  1UBY A;  3N1V F;  5ILY A;  2Q58 A;  4NKF A;  5JUZ F;  5JV1 F;  3EZ3 A;  5DJP F;  4GA3 A;  5A0I A;  3WCG A;  2ZEU A;  4KPJ A;  5C05 A;  3G4D A;  5DGM F;  3M9U A;  3UCA A;  3VJA A;  3LOM A;  3IBA A;  3WCF A;  5IMI A;  5IM1 A;  5KSX F;  3LSN A;  2F92 F;  5DGS F;  3AE0 A;  1YYT A;  3LG5 A;  4H5C F;  1WKZ A;  1N20 A;  4LXW A;  4K10 A;  4KVY A;  3P8L A;  4E1E A;  2OPN A;  2Z7H A;  2VF6 A;  1WL0 A;  1YQ7 A;  4RNQ A;  5HNA A;  3WEK A;  1V4K A;  3ID0 A;  4RXA A;  1VG7 A;  1WL2 A;  4KFA A;  4KVI A;  2PS4 A;  5AHU B;  3SDQ A;  3KRA B;  2E8X A;  2F94 F;  5B0K A;  2Q9Y A;  3ASX A;  1N21 A;  4OMG A;  2AET A;  3M01 A;  3WSA A;  3DYG A;  3N3D A;  1ZW5 A;  4OKZ A;  1YJ4 A;  3N49 F;  1WY0 A;  3WE9 A;  3ACW A;  5HN7 A;  4E9Z A;  3WJN A;  4DWB A;  3KRF B;  2F89 F;  4KQU A;  5DW7 A;  2ZCR A;  5B0M A;  5CG6 A;  3OAC B;  3SAE A;  5ILI A;  2F8Z F;  5IMN A;  2OA6 A;  3N1W F;  4KKM A;  3KRO A;  3LLW A;  1KIY A;  4UMJ A;  4GP1 A;  5AYP A;  2AZL A;  4XQS F;  2J1O A;  2E8T A;  5IK0 A;  3KRP B;  5DHI A;  3WEI A;  1N24 A;  1VG2 A;  2P1C A;  4LA5 A;  3IPI A;  5B0J A;  4DWG A;  2I19 A;  3OAB B;  3ZMC A;  1RQJ A;  2E95 A;  5ER8 A;  4NKE A;  4XQR F;  3WEH A;  3KRC A;  3KBK A;  3ADZ A;  5B00 A;  5HN8 A;  4LTV A;  2Q80 A;  2ZCQ A;  1HXG A;  4LFV F;  4N1Z F;  1YYQ A;  2E8W A;  4E9U A;  5IKH A;  2QIS A;  4KPD A;  5DGN F;  5E8H A;  1YHK A;  5CG5 A;  5A0K A;  4LUU A;  3ZOU A;  2ZEV A;  5JV0 F;  4NFJ F;  1VG6 A;  2E94 A;  4GP2 A;  3PH7 A;  4DZW A;  1V4E A;  4F62 A;  4LFE A;  3QKC A;  3WJK A;  4KQ5 A;  4NFK F;  3DYH A;  3V66 A;  2E92 A;  4FP4 A;  5EAU A;  4RXE A;  4HD1 A;  4QPF A;  1YYS A;  3N6K F;  4JXY A;  1JFG A;  3SDU A;  3VJ8 A;  1JFA A;  2Z78 A;  3ICN A;  5B01 A;  5IMP A;  3LZ9 A;  3WEG A;  1YV5 A;  3ACY A;  3Q2Z A;  5DZ2 A;  2PS8 A;  1RTR A;  3TC1 A;  4RYP A;  2OPM A;  4JXN A;  1UBW A;  3CC9 A;  4NFI F;  3WCA A;  1EZF A;  2Q9Z A;  4LPH F;  4DHD A;  3TFN A;  3EGT A;  3M02 A;  3W7F A;  5ILJ A;  1YYR A;  3VJB A;  3LVS A;  3WEJ A;  5ERM A;  4Q23 A;  3RYE A;  3BNX A;  4WK5 A;  4L2X F;  3WCL A;  4P0W A;  5EAT A;  3SDT A;  4F6X A;  3OYR A;  1VG4 A;  3VJE A;  3N0G A;  3NPK A;  3QQV A;  1HX9 A;  2E8U A;  5IK6 A;  4JZX A;  4MC0 A;  2RAH A;  3LMD A;  3N5J F;  2E93 A;  2Z4V A;  2F7M F;  4RXC A;  3PYA A;  3AQC B;  4OKM A;  3N46 F;  3TS7 A;  1V4I A;  3VJ9 A;  5ERO A;  3KRF A;  2H8O A;  2J5C A;  3KRO B;  3OAC A;  2PS7 A;  5ILK A;  4EA0 A;  5DIQ F;  5B03 A;  4P0X A;  1N1B A;  4JVJ F;  3MZV A;  4LZ0 A;  3ZCD A;  3LJI A;  4EA1 A;  5DHK A;  3P5P A;  4N9U A;  3PKO A;  1WL1 A;  5IL8 A;  3OAB A;  3VJD A;  1N22 A;  3M0G A;  2ZCO A;  3N3L F; 
#chains in the Genus database with same CATH topology
 4XQT F;  5H9D A;  4LTZ A;  3KRC B;  2ZCS A;  5IK9 A;  2FTZ A;  1VG3 A;  1DI1 A;  4NG6 A;  3NF2 A;  4H5D F;  3WJO A;  5HN9 A;  2PS6 A;  4DI5 A;  5A0J A;  4KUX A;  4F6V A;  1WMW A;  3WSB A;  3CKE A;  1KIZ A;  5E8K A;  3ICM A;  3G4F A;  2AEK A;  3RYW A;  4H5E F;  3VJC A;  4LFG A;  3V1V A;  3TFP A;  2Z7I A;  3WCE A;  3KB9 A;  3S9V A;  5DJR F;  4GAX A;  1WL3 A;  4ZQ8 A;  3V1X A;  1UBV A;  3WCH A;  5ILZ A;  2E91 A;  4MC8 A;  5JV2 F;  1N1Z A;  4EA2 A;  1PS1 A;  4DXJ A;  4KWD A;  5E8L A;  3RBM A;  5ILD A;  1FPS A;  4KK2 A;  3WCM A;  5B0L A;  4LZC A;  4QXS F;  5B02 A;  3LK5 A;  4DEM F;  2ONG A;  3AQB B;  2Z4Y A;  3WCI A;  3WCJ A;  1V4H A;  1RQI A;  2E90 A;  3WCD A;  3LGZ B;  3KRA A;  4MC3 A;  4KVD A;  3WCC A;  3LDW A;  2ZY1 A;  3BNY A;  2OGD A;  5AEL A;  4JZB A;  3MAV A;  3RMG A;  4JYX A;  3ICZ A;  1V4J A;  3P41 A;  3DYF A;  2E8V A;  3CP6 A;  3SDV A;  2ONH A;  3P5R A;  2Z4Z A;  2J1P A;  3Q2Q A;  5IL3 A;  4OMH A;  2F8C F;  3LEE A;  3ACX A;  4LLT A;  3B7L A;  3NRI A;  5I1U A;  2F9K F;  1N23 A;  3KRP A;  5AFX A;  2AZJ A;  2Z4X A;  3M00 A;  3ZMB A;  3ZL6 A;  3LGK A;  4FJQ A;  3Q30 A;  1HM4 A;  2AEL A;  5EAS A;  4KVW A;  2E4O A;  2DH4 A;  1YHM A;  4KQS A;  3Q1O A;  1DGP A;  1HXA A;  4P0V A;  5ERN A;  5ILH A;  4LPG F;  2O1O A;  2Z52 A;  3SDR A;  2Z4W A;  3P8R A;  4NUA A;  4PVY F;  4LLS A;  5IN8 A;  5JA0 F;  2PS5 A;  4OGU A;  3S4J A;  4LOB A;  2FOR A;  1YYU A;  4LIX A;  5IKA A;  1HXC A;  3PYB A;  3WCB A;  3AQ0 A;  3N0F A;  5B0I A;  1YHL A;  3N45 F;  3N5H F;  3NPR A;  3WEF A;  3WC9 A;  5DJV F;  1HM7 A;  4LZ3 A;  4RXD A;  1UBX A;  2AZK A;  3TFV A;  4PVX F;  2Z50 A;  3ICK A;  3EFQ A;  5IVG A;  4LA6 A;  3APZ A;  3PDE A;  2EWG A;  1UBY A;  3N1V F;  5ILY A;  2Q58 A;  4NKF A;  5JUZ F;  5JV1 F;  3EZ3 A;  5DJP F;  4GA3 A;  5A0I A;  3WCG A;  2ZEU A;  4KPJ A;  5C05 A;  3G4D A;  5DGM F;  3M9U A;  3UCA A;  3VJA A;  3LOM A;  3IBA A;  3WCF A;  5IMI A;  5IM1 A;  5KSX F;  3LSN A;  2F92 F;  5DGS F;  3AE0 A;  1YYT A;  3LG5 A;  4H5C F;  1WKZ A;  1N20 A;  4LXW A;  4K10 A;  4KVY A;  3P8L A;  4E1E A;  2OPN A;  2Z7H A;  2VF6 A;  1WL0 A;  1YQ7 A;  4RNQ A;  5HNA A;  3WEK A;  1V4K A;  3ID0 A;  4RXA A;  1VG7 A;  1WL2 A;  4KFA A;  4KVI A;  2PS4 A;  5AHU B;  3SDQ A;  3KRA B;  2E8X A;  2F94 F;  5B0K A;  2Q9Y A;  3ASX A;  1N21 A;  4OMG A;  2AET A;  3M01 A;  3WSA A;  3DYG A;  3N3D A;  1ZW5 A;  4OKZ A;  1YJ4 A;  3N49 F;  1WY0 A;  3WE9 A;  3ACW A;  5HN7 A;  4E9Z A;  3WJN A;  4DWB A;  3KRF B;  2F89 F;  4KQU A;  5DW7 A;  2ZCR A;  5B0M A;  5CG6 A;  3OAC B;  3SAE A;  5ILI A;  2F8Z F;  5IMN A;  2OA6 A;  3N1W F;  4KKM A;  3KRO A;  3LLW A;  1KIY A;  4UMJ A;  4GP1 A;  5AYP A;  2AZL A;  4XQS F;  2J1O A;  2E8T A;  5IK0 A;  3KRP B;  5DHI A;  3WEI A;  1N24 A;  1VG2 A;  2P1C A;  4LA5 A;  3IPI A;  5B0J A;  4DWG A;  2I19 A;  3OAB B;  3ZMC A;  1RQJ A;  2E95 A;  5ER8 A;  4NKE A;  4XQR F;  3WEH A;  3KRC A;  3KBK A;  3ADZ A;  5B00 A;  5HN8 A;  4LTV A;  2Q80 A;  2ZCQ A;  1HXG A;  4LFV F;  4N1Z F;  1YYQ A;  2E8W A;  4E9U A;  5IKH A;  2QIS A;  4KPD A;  5DGN F;  5E8H A;  1YHK A;  5CG5 A;  5A0K A;  4LUU A;  3ZOU A;  2ZEV A;  5JV0 F;  4NFJ F;  1VG6 A;  2E94 A;  4GP2 A;  3PH7 A;  4DZW A;  1V4E A;  4F62 A;  4LFE A;  3QKC A;  3WJK A;  4KQ5 A;  4NFK F;  3DYH A;  3V66 A;  2E92 A;  4FP4 A;  5EAU A;  4RXE A;  4HD1 A;  4QPF A;  1YYS A;  3N6K F;  4JXY A;  1JFG A;  3SDU A;  3VJ8 A;  1JFA A;  2Z78 A;  3ICN A;  5B01 A;  5IMP A;  3LZ9 A;  3WEG A;  1YV5 A;  3ACY A;  3Q2Z A;  5DZ2 A;  2PS8 A;  1RTR A;  3TC1 A;  4RYP A;  2OPM A;  4JXN A;  1UBW A;  3CC9 A;  4NFI F;  3WCA A;  1EZF A;  2Q9Z A;  4LPH F;  4DHD A;  3TFN A;  3EGT A;  3M02 A;  3W7F A;  5ILJ A;  1YYR A;  3VJB A;  3LVS A;  3WEJ A;  5ERM A;  4Q23 A;  3RYE A;  3BNX A;  4WK5 A;  4L2X F;  3WCL A;  4P0W A;  5EAT A;  3SDT A;  4F6X A;  3OYR A;  1VG4 A;  3VJE A;  3N0G A;  3NPK A;  3QQV A;  1HX9 A;  2E8U A;  5IK6 A;  4JZX A;  4MC0 A;  2RAH A;  3LMD A;  3N5J F;  2E93 A;  2Z4V A;  2F7M F;  4RXC A;  3PYA A;  3AQC B;  4OKM A;  3N46 F;  3TS7 A;  1V4I A;  3VJ9 A;  5ERO A;  3KRF A;  2H8O A;  2J5C A;  3KRO B;  3OAC A;  2PS7 A;  5ILK A;  4EA0 A;  5DIQ F;  5B03 A;  4P0X A;  1N1B A;  4JVJ F;  3MZV A;  4LZ0 A;  3ZCD A;  3LJI A;  4EA1 A;  5DHK A;  3P5P A;  4N9U A;  3PKO A;  1WL1 A;  5IL8 A;  3OAB A;  3VJD A;  1N22 A;  3M0G A;  2ZCO A;  3N3L F; 
#chains in the Genus database with same CATH homology
 4XQT F;  5H9D A;  4LTZ A;  3KRC B;  2ZCS A;  5IK9 A;  2FTZ A;  1VG3 A;  1DI1 A;  4NG6 A;  3NF2 A;  4H5D F;  3WJO A;  5HN9 A;  2PS6 A;  4DI5 A;  5A0J A;  4KUX A;  4F6V A;  1WMW A;  3WSB A;  3CKE A;  1KIZ A;  5E8K A;  3ICM A;  3G4F A;  2AEK A;  3RYW A;  4H5E F;  3VJC A;  4LFG A;  3V1V A;  3TFP A;  2Z7I A;  3WCE A;  3KB9 A;  3S9V A;  5DJR F;  4GAX A;  1WL3 A;  4ZQ8 A;  3V1X A;  1UBV A;  3WCH A;  5ILZ A;  2E91 A;  4MC8 A;  5JV2 F;  1N1Z A;  4EA2 A;  1PS1 A;  4DXJ A;  4KWD A;  5E8L A;  3RBM A;  5ILD A;  1FPS A;  4KK2 A;  3WCM A;  5B0L A;  4LZC A;  4QXS F;  5B02 A;  3LK5 A;  4DEM F;  2ONG A;  3AQB B;  2Z4Y A;  3WCI A;  3WCJ A;  1V4H A;  1RQI A;  2E90 A;  3WCD A;  3LGZ B;  3KRA A;  4MC3 A;  4KVD A;  3WCC A;  3LDW A;  2ZY1 A;  3BNY A;  2OGD A;  5AEL A;  4JZB A;  3MAV A;  3RMG A;  4JYX A;  3ICZ A;  1V4J A;  3P41 A;  3DYF A;  2E8V A;  3CP6 A;  3SDV A;  2ONH A;  3P5R A;  2Z4Z A;  2J1P A;  3Q2Q A;  5IL3 A;  4OMH A;  2F8C F;  3LEE A;  3ACX A;  4LLT A;  3B7L A;  3NRI A;  5I1U A;  2F9K F;  1N23 A;  3KRP A;  5AFX A;  2AZJ A;  2Z4X A;  3M00 A;  3ZMB A;  3ZL6 A;  3LGK A;  4FJQ A;  3Q30 A;  1HM4 A;  2AEL A;  5EAS A;  4KVW A;  2E4O A;  2DH4 A;  1YHM A;  4KQS A;  3Q1O A;  1DGP A;  1HXA A;  4P0V A;  5ERN A;  5ILH A;  4LPG F;  2O1O A;  2Z52 A;  3SDR A;  2Z4W A;  3P8R A;  4NUA A;  4PVY F;  4LLS A;  5IN8 A;  5JA0 F;  2PS5 A;  4OGU A;  3S4J A;  4LOB A;  2FOR A;  1YYU A;  4LIX A;  5IKA A;  1HXC A;  3PYB A;  3WCB A;  3AQ0 A;  3N0F A;  5B0I A;  1YHL A;  3N45 F;  3N5H F;  3NPR A;  3WEF A;  3WC9 A;  5DJV F;  1HM7 A;  4LZ3 A;  4RXD A;  1UBX A;  2AZK A;  3TFV A;  4PVX F;  2Z50 A;  3ICK A;  3EFQ A;  5IVG A;  4LA6 A;  3APZ A;  3PDE A;  2EWG A;  1UBY A;  3N1V F;  5ILY A;  2Q58 A;  4NKF A;  5JUZ F;  5JV1 F;  3EZ3 A;  5DJP F;  4GA3 A;  5A0I A;  3WCG A;  2ZEU A;  4KPJ A;  5C05 A;  3G4D A;  5DGM F;  3M9U A;  3UCA A;  3VJA A;  3LOM A;  3IBA A;  3WCF A;  5IMI A;  5IM1 A;  5KSX F;  3LSN A;  2F92 F;  5DGS F;  3AE0 A;  1YYT A;  3LG5 A;  4H5C F;  1WKZ A;  1N20 A;  4LXW A;  4K10 A;  4KVY A;  3P8L A;  4E1E A;  2OPN A;  2Z7H A;  2VF6 A;  1WL0 A;  1YQ7 A;  4RNQ A;  5HNA A;  3WEK A;  1V4K A;  3ID0 A;  4RXA A;  1VG7 A;  1WL2 A;  4KFA A;  4KVI A;  2PS4 A;  5AHU B;  3SDQ A;  3KRA B;  2E8X A;  2F94 F;  5B0K A;  2Q9Y A;  3ASX A;  1N21 A;  4OMG A;  2AET A;  3M01 A;  3WSA A;  3DYG A;  3N3D A;  1ZW5 A;  4OKZ A;  1YJ4 A;  3N49 F;  1WY0 A;  3WE9 A;  3ACW A;  5HN7 A;  4E9Z A;  3WJN A;  4DWB A;  3KRF B;  2F89 F;  4KQU A;  5DW7 A;  2ZCR A;  5B0M A;  5CG6 A;  3OAC B;  3SAE A;  5ILI A;  2F8Z F;  5IMN A;  2OA6 A;  3N1W F;  4KKM A;  3KRO A;  3LLW A;  1KIY A;  4UMJ A;  4GP1 A;  5AYP A;  2AZL A;  4XQS F;  2J1O A;  2E8T A;  5IK0 A;  3KRP B;  5DHI A;  3WEI A;  1N24 A;  1VG2 A;  2P1C A;  4LA5 A;  3IPI A;  5B0J A;  4DWG A;  2I19 A;  3OAB B;  3ZMC A;  1RQJ A;  2E95 A;  5ER8 A;  4NKE A;  4XQR F;  3WEH A;  3KRC A;  3KBK A;  3ADZ A;  5B00 A;  5HN8 A;  4LTV A;  2Q80 A;  2ZCQ A;  1HXG A;  4LFV F;  4N1Z F;  1YYQ A;  2E8W A;  4E9U A;  5IKH A;  2QIS A;  4KPD A;  5DGN F;  5E8H A;  1YHK A;  5CG5 A;  5A0K A;  4LUU A;  3ZOU A;  2ZEV A;  5JV0 F;  4NFJ F;  1VG6 A;  2E94 A;  4GP2 A;  3PH7 A;  4DZW A;  1V4E A;  4F62 A;  4LFE A;  3QKC A;  3WJK A;  4KQ5 A;  4NFK F;  3DYH A;  3V66 A;  2E92 A;  4FP4 A;  5EAU A;  4RXE A;  4HD1 A;  4QPF A;  1YYS A;  3N6K F;  4JXY A;  1JFG A;  3SDU A;  3VJ8 A;  1JFA A;  2Z78 A;  3ICN A;  5B01 A;  5IMP A;  3LZ9 A;  3WEG A;  1YV5 A;  3ACY A;  3Q2Z A;  5DZ2 A;  2PS8 A;  1RTR A;  3TC1 A;  4RYP A;  2OPM A;  4JXN A;  1UBW A;  3CC9 A;  4NFI F;  3WCA A;  1EZF A;  2Q9Z A;  4LPH F;  4DHD A;  3TFN A;  3EGT A;  3M02 A;  3W7F A;  5ILJ A;  1YYR A;  3VJB A;  3LVS A;  3WEJ A;  5ERM A;  4Q23 A;  3RYE A;  3BNX A;  4WK5 A;  4L2X F;  3WCL A;  4P0W A;  5EAT A;  3SDT A;  4F6X A;  3OYR A;  1VG4 A;  3VJE A;  3N0G A;  3NPK A;  3QQV A;  1HX9 A;  2E8U A;  5IK6 A;  4JZX A;  4MC0 A;  2RAH A;  3LMD A;  3N5J F;  2E93 A;  2Z4V A;  2F7M F;  4RXC A;  3PYA A;  3AQC B;  4OKM A;  3N46 F;  3TS7 A;  1V4I A;  3VJ9 A;  5ERO A;  3KRF A;  2H8O A;  2J5C A;  3KRO B;  3OAC A;  2PS7 A;  5ILK A;  4EA0 A;  5DIQ F;  5B03 A;  4P0X A;  1N1B A;  4JVJ F;  3MZV A;  4LZ0 A;  3ZCD A;  3LJI A;  4EA1 A;  5DHK A;  3P5P A;  4N9U A;  3PKO A;  1WL1 A;  5IL8 A;  3OAB A;  3VJD A;  1N22 A;  3M0G A;  2ZCO A;  3N3L F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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