5JV2F

Crystal structure of human fpps in complex with an allosteric inhibitor mit-01-055
Total Genus 123
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
123
sequence length
341
structure length
331
Chain Sequence
YAQEKQDFVQHFSQIVRVLTEPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
molecule keywords Farnesyl pyrophosphate synthase
publication title Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase.
pubmed doi rcsb
source organism Homo sapiens
total genus 123
structure length 331
sequence length 341
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2016-05-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 5jv2F00
2OGDA 5IK0A 1HM4A 4LZ3A 4OKZA 3KRCA 4NG6A 2ZEUA 2ZCQA 2FTZA 4F6XA 3LJIA 4NFIF 4XQSF 5JV1F 3IPIA 4RXDA 3VJBA 2E91A 4LFVF 4KVWA 3DYGA 4LFEA 1V4IA 5DW7A 3PH7A 2Z4ZA 3WEHA 4ZQ8A 3VJEA 1YHLA 5EROA 3ICNA 3WCAA 4HD1A 2Z7IA 5DJVF 3EGTA 4KVIA 3G4FA 4DEMF 3Q2QA 3B7LA 3OABA 3N3LF 3WEFA 3DYFA 3PYAA 3VJAA 4NKEA 3TFPA 3WEIA 1N20A 3RBMA 5ILDA 4LPGF 2AELA 1YYRA 2AETA 3ID0A 3LGZB 3V66A 2ZEVA 5ERMA 5EAUA 2ONHA 2F92F 2Q58A 3KROB 1WL2A 2Z50A 3V1VA 5IK9A 5DJRF 2J1PA 4JZXA 5DGSF 4N9UA 2AZJA 1WL0A 2E8TA 3WCEA 4PVYF 5IMIA 3AQCB 2AZKA 4GP2A 3WCLA 3MAVA 5DIQF 4E9ZA 5ILKA 3CP6A 1YJ4A 4QPFA 2ZY1A 2F89F 3NF2A 4H5DF 4LXWA 4DWGA 3N1WF 1HXCA 5ILZA 2P1CA 3PKOA 3VJ9A 3N0FA 5A0KA 1YHKA 1N22A 2OPNA 3P5RA 2Z4VA 3Q30A 2VF6A 1WL1A 1UBXA 3UCAA 1N21A 3PDEA 4WK5A 1N24A 2RAHA 4EA0A 3ICKA 4KK2A 3WEKA 3TS7A 3WCHA 1WMWA 2DH4A 5JUZF 3M9UA 5B02A 2PS8A 4KUXA 1VG7A 2PS6A 3SDQA 1WL3A 5IL3A 4LIXA 1V4EA 3LDWA 1RTRA 2AZLA 2E94A 3ACYA 5AHUB 5DHKA 5IK6A 2OPMA 3W7FA 3IBAA 4NFKF 1JFAA 1V4JA 4LZCA 3RMGA 3AQ0A 3WSBA 1JFGA 4KQUA 1EZFA 5B0KA 5JV0F 1HX9A 1UBYA 4LLSA 1UBVA 4DWBA 3VJCA 3M0GA 3CKEA 4GAXA 3LEEA 1RQIA 4RXCA 4DHDA 5AELA 3EZ3A 5JA0F 3WJKA 3KBKA 4LTVA 4F62A 5B03A 5B0IA 1KIYA 3MZVA 1UBWA 2E90A 5B0MA 2J1OA 4P0XA 1VG2A 1HXAA 2PS5A 5AYPA 5B00A 3LMDA 3S4JA 2Z78A 4OMGA 4N1ZF 5JV2F 3OACA 5CG5A 4XQRF 5IM1A 4PVXF 3RYWA 3KRFA 3WCFA 5B01A 2Z52A 3P8LA 4RNQA 1FPSA 3NPKA 2Q80A 2AEKA 3KRCB 3KRPA 4KKMA 2H8OA 3ZCDA 1YYQA 2PS7A 1WKZA 3M02A 4FJQA 3WCDA 2I19A 4GP1A 2E93A 5IKAA 4KPDA 3N5HF 5HNAA 2O1OA 2QISA 4Q23A 2F9KF 4DZWA 3WE9A 1V4KA 3KB9A 3AE0A 3ZMCA 5E8HA 3QQVA 4JZBA 3APZA 4KWDA 3RYEA 3V1XA 1VG4A 3N49F 5DGMF 4MC0A 2Q9ZA 2Z4WA 3ICZA 5EASA 5AFXA 3ZOUA 3SAEA 4UMJA 4LA6A 3ZMBA 5HN8A 3G4DA 1N1ZA 1VG6A 5ER8A 3N45F 3WC9A 1PS1A 3LGKA 1YYSA 3WJNA 4RXAA 5ILIA 1YQ7A 3OABB 4NKFA 1YV5A 1YYUA 4LOBA 3CC9A 4F6VA 5ERNA 3M01A 3N6KF 3SDUA 5A0JA 5B0LA 4JYXA 1WY0A 3SDTA 1N1BA 2EWGA 3BNYA 2ONGA 2E4OA 5IVGA 3KRFB 4JVJF 5C05A 2J5CA 2FORA 3NPRA 3KRAA 2E8VA 1DGPA 3KRPB 4E9UA 2E95A 3OYRA 2OA6A 4LFGA 5ILHA 3WEJA 3EFQA 5E8KA 4JXYA 4RXEA 3LLWA 4MC8A 4DXJA 5I1UA 3NRIA 1RQJA 4E1EA 2E92A 5EATA 1V4HA 3QKCA 2F94F 1ZW5A 4EA2A 3N0GA 4JXNA 4KPJA 4OGUA 3WEGA 5HN7A 3LVSA 3WCGA 4DI5A 3ADZA 3ACXA 3WCIA 3WCCA 3WCBA 2ZCRA 3N1VF 4H5EF 5A0IA 3WJOA 1HM7A 2F7MF 5IN8A 3P5PA 3N46F 2ZCOA 5IMNA 3M00A 3VJ8A 4RYPA 2Q9YA 4LA5A 5E8LA 2Z7HA 3N3DA 4NUAA 1DI1A 2F8ZF 4H5CF 3TFNA 4LZ0A 4LPHF 3N5JF 1N23A 2ZCSA 1HXGA 3LG5A 4EA1A 5ILJA 1KIZA 1VG3A 3Q1OA 2E8UA 5B0JA 3DYHA 4GA3A 4OMHA 4KQ5A 3SDVA 3WSAA 3VJDA 3SDRA 2F8CF 5DJPF 3ICMA 5IKHA 4KVDA 2E8XA 3BNXA 3KRAB 3WCMA 4LLTA 3WCJA 4FP4A 5CG6A 5DGNF 5IMPA 3TFVA 4OKMA 4MC3A 2Z4YA 3ZL6A 3AQBB 5DHIA 3ASXA 4LTZA 4K10A 3S9VA 3P41A 3PYBA 4XQTF 5KSXF 4KQSA 2PS4A 4KVYA 4NFJF 3LSNA 3Q2ZA 5DZ2A 2Z4XA 5HN9A 3ACWA 1YYTA 4P0WA 4L2XF 4P0VA 1YHMA 3OACB 3TC1A 2E8WA 4KFAA 3LOMA 3KROA 4LUUA 5IL8A 3LK5A 5H9DA 3LZ9A 3P8RA 5ILYA 4QXSF
chains in the Genus database with same CATH superfamily
2OGDA 5IK0A 1HM4A 4LZ3A 4OKZA 3KRCA 4NG6A 2ZEUA 2ZCQA 2FTZA 4F6XA 3LJIA 4NFIF 4XQSF 5JV1F 3IPIA 4RXDA 3VJBA 2E91A 4LFVF 4KVWA 3DYGA 4LFEA 1V4IA 5DW7A 3PH7A 2Z4ZA 3WEHA 4ZQ8A 3VJEA 1YHLA 5EROA 3ICNA 3WCAA 4HD1A 2Z7IA 5DJVF 3EGTA 4KVIA 3G4FA 4DEMF 3Q2QA 3B7LA 3OABA 3N3LF 3WEFA 3DYFA 3PYAA 3VJAA 4NKEA 3TFPA 3WEIA 1N20A 3RBMA 5ILDA 4LPGF 2AELA 1YYRA 2AETA 3ID0A 3LGZB 3V66A 2ZEVA 5ERMA 5EAUA 2ONHA 2F92F 2Q58A 3KROB 1WL2A 2Z50A 3V1VA 5IK9A 5DJRF 2J1PA 4JZXA 5DGSF 4N9UA 2AZJA 1WL0A 2E8TA 3WCEA 4PVYF 5IMIA 3AQCB 2AZKA 4GP2A 3WCLA 3MAVA 5DIQF 4E9ZA 5ILKA 3CP6A 1YJ4A 4QPFA 2ZY1A 2F89F 3NF2A 4H5DF 4LXWA 4DWGA 3N1WF 1HXCA 5ILZA 2P1CA 3PKOA 3VJ9A 3N0FA 5A0KA 1YHKA 1N22A 2OPNA 3P5RA 2Z4VA 3Q30A 2VF6A 1WL1A 1UBXA 3UCAA 1N21A 3PDEA 4WK5A 1N24A 2RAHA 4EA0A 3ICKA 4KK2A 3WEKA 3TS7A 3WCHA 1WMWA 2DH4A 5JUZF 3M9UA 5B02A 2PS8A 4KUXA 1VG7A 2PS6A 3SDQA 1WL3A 5IL3A 4LIXA 1V4EA 3LDWA 1RTRA 2AZLA 2E94A 3ACYA 5AHUB 5DHKA 5IK6A 2OPMA 3W7FA 3IBAA 4NFKF 1JFAA 1V4JA 4LZCA 3RMGA 3AQ0A 3WSBA 1JFGA 4KQUA 1EZFA 5B0KA 5JV0F 1HX9A 1UBYA 4LLSA 1UBVA 4DWBA 3VJCA 3M0GA 3CKEA 4GAXA 3LEEA 1RQIA 4RXCA 4DHDA 5AELA 3EZ3A 5JA0F 3WJKA 3KBKA 4LTVA 4F62A 5B03A 5B0IA 1KIYA 3MZVA 1UBWA 2E90A 5B0MA 2J1OA 4P0XA 1VG2A 1HXAA 2PS5A 5AYPA 5B00A 3LMDA 3S4JA 2Z78A 4OMGA 4N1ZF 5JV2F 3OACA 5CG5A 4XQRF 5IM1A 4PVXF 3RYWA 3KRFA 3WCFA 5B01A 2Z52A 3P8LA 4RNQA 1FPSA 3NPKA 2Q80A 2AEKA 3KRCB 3KRPA 4KKMA 2H8OA 3ZCDA 1YYQA 2PS7A 1WKZA 3M02A 4FJQA 3WCDA 2I19A 4GP1A 2E93A 5IKAA 4KPDA 3N5HF 5HNAA 2O1OA 2QISA 4Q23A 2F9KF 4DZWA 3WE9A 1V4KA 3KB9A 3AE0A 3ZMCA 5E8HA 3QQVA 4JZBA 3APZA 4KWDA 3RYEA 3V1XA 1VG4A 3N49F 5DGMF 4MC0A 2Q9ZA 2Z4WA 3ICZA 5EASA 5AFXA 3ZOUA 3SAEA 4UMJA 4LA6A 3ZMBA 5HN8A 3G4DA 1N1ZA 1VG6A 5ER8A 3N45F 3WC9A 1PS1A 3LGKA 1YYSA 3WJNA 4RXAA 5ILIA 1YQ7A 3OABB 4NKFA 1YV5A 1YYUA 4LOBA 3CC9A 4F6VA 5ERNA 3M01A 3N6KF 3SDUA 5A0JA 5B0LA 4JYXA 1WY0A 3SDTA 1N1BA 2EWGA 3BNYA 2ONGA 2E4OA 5IVGA 3KRFB 4JVJF 5C05A 2J5CA 2FORA 3NPRA 3KRAA 2E8VA 1DGPA 3KRPB 4E9UA 2E95A 3OYRA 2OA6A 4LFGA 5ILHA 3WEJA 3EFQA 5E8KA 4JXYA 4RXEA 3LLWA 4MC8A 4DXJA 5I1UA 3NRIA 1RQJA 4E1EA 2E92A 5EATA 1V4HA 3QKCA 2F94F 1ZW5A 4EA2A 3N0GA 4JXNA 4KPJA 4OGUA 3WEGA 5HN7A 3LVSA 3WCGA 4DI5A 3ADZA 3ACXA 3WCIA 3WCCA 3WCBA 2ZCRA 3N1VF 4H5EF 5A0IA 3WJOA 1HM7A 2F7MF 5IN8A 3P5PA 3N46F 2ZCOA 5IMNA 3M00A 3VJ8A 4RYPA 2Q9YA 4LA5A 5E8LA 2Z7HA 3N3DA 4NUAA 1DI1A 2F8ZF 4H5CF 3TFNA 4LZ0A 4LPHF 3N5JF 1N23A 2ZCSA 1HXGA 3LG5A 4EA1A 5ILJA 1KIZA 1VG3A 3Q1OA 2E8UA 5B0JA 3DYHA 4GA3A 4OMHA 4KQ5A 3SDVA 3WSAA 3VJDA 3SDRA 2F8CF 5DJPF 3ICMA 5IKHA 4KVDA 2E8XA 3BNXA 3KRAB 3WCMA 4LLTA 3WCJA 4FP4A 5CG6A 5DGNF 5IMPA 3TFVA 4OKMA 4MC3A 2Z4YA 3ZL6A 3AQBB 5DHIA 3ASXA 4LTZA 4K10A 3S9VA 3P41A 3PYBA 4XQTF 5KSXF 4KQSA 2PS4A 4KVYA 4NFJF 3LSNA 3Q2ZA 5DZ2A 2Z4XA 5HN9A 3ACWA 1YYTA 4P0WA 4L2XF 4P0VA 1YHMA 3OACB 3TC1A 2E8WA 4KFAA 3LOMA 3KROA 4LUUA 5IL8A 3LK5A 5H9DA 3LZ9A 3P8RA 5ILYA 4QXSF
chains in the Genus database with same CATH topology
2OGDA 5IK0A 1HM4A 4LZ3A 4OKZA 3KRCA 4NG6A 2ZEUA 2ZCQA 2FTZA 4F6XA 3LJIA 4NFIF 4XQSF 5JV1F 3IPIA 4RXDA 3VJBA 2E91A 4LFVF 4KVWA 3DYGA 4LFEA 1V4IA 5DW7A 3PH7A 2Z4ZA 3WEHA 4ZQ8A 3VJEA 1YHLA 5EROA 3ICNA 3WCAA 4HD1A 2Z7IA 5DJVF 3EGTA 4KVIA 3G4FA 4DEMF 3Q2QA 3B7LA 3OABA 3N3LF 3WEFA 3DYFA 3PYAA 3VJAA 4NKEA 3TFPA 3WEIA 1N20A 3RBMA 5ILDA 4LPGF 2AELA 1YYRA 2AETA 3ID0A 3LGZB 3V66A 2ZEVA 5ERMA 5EAUA 2ONHA 2F92F 2Q58A 3KROB 1WL2A 2Z50A 3V1VA 5IK9A 5DJRF 2J1PA 4JZXA 5DGSF 4N9UA 2AZJA 1WL0A 2E8TA 3WCEA 4PVYF 5IMIA 3AQCB 2AZKA 4GP2A 3WCLA 3MAVA 5DIQF 4E9ZA 5ILKA 3CP6A 1YJ4A 4QPFA 2ZY1A 2F89F 3NF2A 4H5DF 4LXWA 4DWGA 3N1WF 1HXCA 5ILZA 2P1CA 3PKOA 3VJ9A 3N0FA 5A0KA 1YHKA 1N22A 2OPNA 3P5RA 2Z4VA 3Q30A 2VF6A 1WL1A 1UBXA 3UCAA 1N21A 3PDEA 4WK5A 1N24A 2RAHA 4EA0A 3ICKA 4KK2A 3WEKA 3TS7A 3WCHA 1WMWA 2DH4A 5JUZF 3M9UA 5B02A 2PS8A 4KUXA 1VG7A 2PS6A 3SDQA 1WL3A 5IL3A 4LIXA 1V4EA 3LDWA 1RTRA 2AZLA 2E94A 3ACYA 5AHUB 5DHKA 5IK6A 2OPMA 3W7FA 3IBAA 4NFKF 1JFAA 1V4JA 4LZCA 3RMGA 3AQ0A 3WSBA 1JFGA 4KQUA 1EZFA 5B0KA 5JV0F 1HX9A 1UBYA 4LLSA 1UBVA 4DWBA 3VJCA 3M0GA 3CKEA 4GAXA 3LEEA 1RQIA 4RXCA 4DHDA 5AELA 3EZ3A 5JA0F 3WJKA 3KBKA 4LTVA 4F62A 5B03A 5B0IA 1KIYA 3MZVA 1UBWA 2E90A 5B0MA 2J1OA 4P0XA 1VG2A 1HXAA 2PS5A 5AYPA 5B00A 3LMDA 3S4JA 2Z78A 4OMGA 4N1ZF 5JV2F 3OACA 5CG5A 4XQRF 5IM1A 4PVXF 3RYWA 3KRFA 3WCFA 5B01A 2Z52A 3P8LA 4RNQA 1FPSA 3NPKA 2Q80A 2AEKA 3KRCB 3KRPA 4KKMA 2H8OA 3ZCDA 1YYQA 2PS7A 1WKZA 3M02A 4FJQA 3WCDA 2I19A 4GP1A 2E93A 5IKAA 4KPDA 3N5HF 5HNAA 2O1OA 2QISA 4Q23A 2F9KF 4DZWA 3WE9A 1V4KA 3KB9A 3AE0A 3ZMCA 5E8HA 3QQVA 4JZBA 3APZA 4KWDA 3RYEA 3V1XA 1VG4A 3N49F 5DGMF 4MC0A 2Q9ZA 2Z4WA 3ICZA 5EASA 5AFXA 3ZOUA 3SAEA 4UMJA 4LA6A 3ZMBA 5HN8A 3G4DA 1N1ZA 1VG6A 5ER8A 3N45F 3WC9A 1PS1A 3LGKA 1YYSA 3WJNA 4RXAA 5ILIA 1YQ7A 3OABB 4NKFA 1YV5A 1YYUA 4LOBA 3CC9A 4F6VA 5ERNA 3M01A 3N6KF 3SDUA 5A0JA 5B0LA 4JYXA 1WY0A 3SDTA 1N1BA 2EWGA 3BNYA 2ONGA 2E4OA 5IVGA 3KRFB 4JVJF 5C05A 2J5CA 2FORA 3NPRA 3KRAA 2E8VA 1DGPA 3KRPB 4E9UA 2E95A 3OYRA 2OA6A 4LFGA 5ILHA 3WEJA 3EFQA 5E8KA 4JXYA 4RXEA 3LLWA 4MC8A 4DXJA 5I1UA 3NRIA 1RQJA 4E1EA 2E92A 5EATA 1V4HA 3QKCA 2F94F 1ZW5A 4EA2A 3N0GA 4JXNA 4KPJA 4OGUA 3WEGA 5HN7A 3LVSA 3WCGA 4DI5A 3ADZA 3ACXA 3WCIA 3WCCA 3WCBA 2ZCRA 3N1VF 4H5EF 5A0IA 3WJOA 1HM7A 2F7MF 5IN8A 3P5PA 3N46F 2ZCOA 5IMNA 3M00A 3VJ8A 4RYPA 2Q9YA 4LA5A 5E8LA 2Z7HA 3N3DA 4NUAA 1DI1A 2F8ZF 4H5CF 3TFNA 4LZ0A 4LPHF 3N5JF 1N23A 2ZCSA 1HXGA 3LG5A 4EA1A 5ILJA 1KIZA 1VG3A 3Q1OA 2E8UA 5B0JA 3DYHA 4GA3A 4OMHA 4KQ5A 3SDVA 3WSAA 3VJDA 3SDRA 2F8CF 5DJPF 3ICMA 5IKHA 4KVDA 2E8XA 3BNXA 3KRAB 3WCMA 4LLTA 3WCJA 4FP4A 5CG6A 5DGNF 5IMPA 3TFVA 4OKMA 4MC3A 2Z4YA 3ZL6A 3AQBB 5DHIA 3ASXA 4LTZA 4K10A 3S9VA 3P41A 3PYBA 4XQTF 5KSXF 4KQSA 2PS4A 4KVYA 4NFJF 3LSNA 3Q2ZA 5DZ2A 2Z4XA 5HN9A 3ACWA 1YYTA 4P0WA 4L2XF 4P0VA 1YHMA 3OACB 3TC1A 2E8WA 4KFAA 3LOMA 3KROA 4LUUA 5IL8A 3LK5A 5H9DA 3LZ9A 3P8RA 5ILYA 4QXSF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OGD A;  5IK0 A;  1HM4 A;  4LZ3 A;  4OKZ A;  3KRC A;  4NG6 A;  2ZEU A;  2ZCQ A;  2FTZ A;  4F6X A;  3LJI A;  4NFI F;  4XQS F;  5JV1 F;  3IPI A;  4RXD A;  3VJB A;  2E91 A;  4LFV F;  4KVW A;  3DYG A;  4LFE A;  1V4I A;  5DW7 A;  3PH7 A;  2Z4Z A;  3WEH A;  4ZQ8 A;  3VJE A;  1YHL A;  5ERO A;  3ICN A;  3WCA A;  4HD1 A;  2Z7I A;  5DJV F;  3EGT A;  4KVI A;  3G4F A;  4DEM F;  3Q2Q A;  3B7L A;  3OAB A;  3N3L F;  3WEF A;  3DYF A;  3PYA A;  3VJA A;  4NKE A;  3TFP A;  3WEI A;  1N20 A;  3RBM A;  5ILD A;  4LPG F;  2AEL A;  1YYR A;  2AET A;  3ID0 A;  3LGZ B;  3V66 A;  2ZEV A;  5ERM A;  5EAU A;  2ONH A;  2F92 F;  2Q58 A;  3KRO B;  1WL2 A;  2Z50 A;  3V1V A;  5IK9 A;  5DJR F;  2J1P A;  4JZX A;  5DGS F;  4N9U A;  2AZJ A;  1WL0 A;  2E8T A;  3WCE A;  4PVY F;  5IMI A;  3AQC B;  2AZK A;  4GP2 A;  3WCL A;  3MAV A;  5DIQ F;  4E9Z A;  5ILK A;  3CP6 A;  1YJ4 A;  4QPF A;  2ZY1 A;  2F89 F;  3NF2 A;  4H5D F;  4LXW A;  4DWG A;  3N1W F;  1HXC A;  5ILZ A;  2P1C A;  3PKO A;  3VJ9 A;  3N0F A;  5A0K A;  1YHK A;  1N22 A;  2OPN A;  3P5R A;  2Z4V A;  3Q30 A;  2VF6 A;  1WL1 A;  1UBX A;  3UCA A;  1N21 A;  3PDE A;  4WK5 A;  1N24 A;  2RAH A;  4EA0 A;  3ICK A;  4KK2 A;  3WEK A;  3TS7 A;  3WCH A;  1WMW A;  2DH4 A;  5JUZ F;  3M9U A;  5B02 A;  2PS8 A;  4KUX A;  1VG7 A;  2PS6 A;  3SDQ A;  1WL3 A;  5IL3 A;  4LIX A;  1V4E A;  3LDW A;  1RTR A;  2AZL A;  2E94 A;  3ACY A;  5AHU B;  5DHK A;  5IK6 A;  2OPM A;  3W7F A;  3IBA A;  4NFK F;  1JFA A;  1V4J A;  4LZC A;  3RMG A;  3AQ0 A;  3WSB A;  1JFG A;  4KQU A;  1EZF A;  5B0K A;  5JV0 F;  1HX9 A;  1UBY A;  4LLS A;  1UBV A;  4DWB A;  3VJC A;  3M0G A;  3CKE A;  4GAX A;  3LEE A;  1RQI A;  4RXC A;  4DHD A;  5AEL A;  3EZ3 A;  5JA0 F;  3WJK A;  3KBK A;  4LTV A;  4F62 A;  5B03 A;  5B0I A;  1KIY A;  3MZV A;  1UBW A;  2E90 A;  5B0M A;  2J1O A;  4P0X A;  1VG2 A;  1HXA A;  2PS5 A;  5AYP A;  5B00 A;  3LMD A;  3S4J A;  2Z78 A;  4OMG A;  4N1Z F;  5JV2 F;  3OAC A;  5CG5 A;  4XQR F;  5IM1 A;  4PVX F;  3RYW A;  3KRF A;  3WCF A;  5B01 A;  2Z52 A;  3P8L A;  4RNQ A;  1FPS A;  3NPK A;  2Q80 A;  2AEK A;  3KRC B;  3KRP A;  4KKM A;  2H8O A;  3ZCD A;  1YYQ A;  2PS7 A;  1WKZ A;  3M02 A;  4FJQ A;  3WCD A;  2I19 A;  4GP1 A;  2E93 A;  5IKA A;  4KPD A;  3N5H F;  5HNA A;  2O1O A;  2QIS A;  4Q23 A;  2F9K F;  4DZW A;  3WE9 A;  1V4K A;  3KB9 A;  3AE0 A;  3ZMC A;  5E8H A;  3QQV A;  4JZB A;  3APZ A;  4KWD A;  3RYE A;  3V1X A;  1VG4 A;  3N49 F;  5DGM F;  4MC0 A;  2Q9Z A;  2Z4W A;  3ICZ A;  5EAS A;  5AFX A;  3ZOU A;  3SAE A;  4UMJ A;  4LA6 A;  3ZMB A;  5HN8 A;  3G4D A;  1N1Z A;  1VG6 A;  5ER8 A;  3N45 F;  3WC9 A;  1PS1 A;  3LGK A;  1YYS A;  3WJN A;  4RXA A;  5ILI A;  1YQ7 A;  3OAB B;  4NKF A;  1YV5 A;  1YYU A;  4LOB A;  3CC9 A;  4F6V A;  5ERN A;  3M01 A;  3N6K F;  3SDU A;  5A0J A;  5B0L A;  4JYX A;  1WY0 A;  3SDT A;  1N1B A;  2EWG A;  3BNY A;  2ONG A;  2E4O A;  5IVG A;  3KRF B;  4JVJ F;  5C05 A;  2J5C A;  2FOR A;  3NPR A;  3KRA A;  2E8V A;  1DGP A;  3KRP B;  4E9U A;  2E95 A;  3OYR A;  2OA6 A;  4LFG A;  5ILH A;  3WEJ A;  3EFQ A;  5E8K A;  4JXY A;  4RXE A;  3LLW A;  4MC8 A;  4DXJ A;  5I1U A;  3NRI A;  1RQJ A;  4E1E A;  2E92 A;  5EAT A;  1V4H A;  3QKC A;  2F94 F;  1ZW5 A;  4EA2 A;  3N0G A;  4JXN A;  4KPJ A;  4OGU A;  3WEG A;  5HN7 A;  3LVS A;  3WCG A;  4DI5 A;  3ADZ A;  3ACX A;  3WCI A;  3WCC A;  3WCB A;  2ZCR A;  3N1V F;  4H5E F;  5A0I A;  3WJO A;  1HM7 A;  2F7M F;  5IN8 A;  3P5P A;  3N46 F;  2ZCO A;  5IMN A;  3M00 A;  3VJ8 A;  4RYP A;  2Q9Y A;  4LA5 A;  5E8L A;  2Z7H A;  3N3D A;  4NUA A;  1DI1 A;  2F8Z F;  4H5C F;  3TFN A;  4LZ0 A;  4LPH F;  3N5J F;  1N23 A;  2ZCS A;  1HXG A;  3LG5 A;  4EA1 A;  5ILJ A;  1KIZ A;  1VG3 A;  3Q1O A;  2E8U A;  5B0J A;  3DYH A;  4GA3 A;  4OMH A;  4KQ5 A;  3SDV A;  3WSA A;  3VJD A;  3SDR A;  2F8C F;  5DJP F;  3ICM A;  5IKH A;  4KVD A;  2E8X A;  3BNX A;  3KRA B;  3WCM A;  4LLT A;  3WCJ A;  4FP4 A;  5CG6 A;  5DGN F;  5IMP A;  3TFV A;  4OKM A;  4MC3 A;  2Z4Y A;  3ZL6 A;  3AQB B;  5DHI A;  3ASX A;  4LTZ A;  4K10 A;  3S9V A;  3P41 A;  3PYB A;  4XQT F;  5KSX F;  4KQS A;  2PS4 A;  4KVY A;  4NFJ F;  3LSN A;  3Q2Z A;  5DZ2 A;  2Z4X A;  5HN9 A;  3ACW A;  1YYT A;  4P0W A;  4L2X F;  4P0V A;  1YHM A;  3OAC B;  3TC1 A;  2E8W A;  4KFA A;  3LOM A;  3KRO A;  4LUU A;  5IL8 A;  3LK5 A;  5H9D A;  3LZ9 A;  3P8R A;  5ILY A;  4QXS F; 
#chains in the Genus database with same CATH topology
 2OGD A;  5IK0 A;  1HM4 A;  4LZ3 A;  4OKZ A;  3KRC A;  4NG6 A;  2ZEU A;  2ZCQ A;  2FTZ A;  4F6X A;  3LJI A;  4NFI F;  4XQS F;  5JV1 F;  3IPI A;  4RXD A;  3VJB A;  2E91 A;  4LFV F;  4KVW A;  3DYG A;  4LFE A;  1V4I A;  5DW7 A;  3PH7 A;  2Z4Z A;  3WEH A;  4ZQ8 A;  3VJE A;  1YHL A;  5ERO A;  3ICN A;  3WCA A;  4HD1 A;  2Z7I A;  5DJV F;  3EGT A;  4KVI A;  3G4F A;  4DEM F;  3Q2Q A;  3B7L A;  3OAB A;  3N3L F;  3WEF A;  3DYF A;  3PYA A;  3VJA A;  4NKE A;  3TFP A;  3WEI A;  1N20 A;  3RBM A;  5ILD A;  4LPG F;  2AEL A;  1YYR A;  2AET A;  3ID0 A;  3LGZ B;  3V66 A;  2ZEV A;  5ERM A;  5EAU A;  2ONH A;  2F92 F;  2Q58 A;  3KRO B;  1WL2 A;  2Z50 A;  3V1V A;  5IK9 A;  5DJR F;  2J1P A;  4JZX A;  5DGS F;  4N9U A;  2AZJ A;  1WL0 A;  2E8T A;  3WCE A;  4PVY F;  5IMI A;  3AQC B;  2AZK A;  4GP2 A;  3WCL A;  3MAV A;  5DIQ F;  4E9Z A;  5ILK A;  3CP6 A;  1YJ4 A;  4QPF A;  2ZY1 A;  2F89 F;  3NF2 A;  4H5D F;  4LXW A;  4DWG A;  3N1W F;  1HXC A;  5ILZ A;  2P1C A;  3PKO A;  3VJ9 A;  3N0F A;  5A0K A;  1YHK A;  1N22 A;  2OPN A;  3P5R A;  2Z4V A;  3Q30 A;  2VF6 A;  1WL1 A;  1UBX A;  3UCA A;  1N21 A;  3PDE A;  4WK5 A;  1N24 A;  2RAH A;  4EA0 A;  3ICK A;  4KK2 A;  3WEK A;  3TS7 A;  3WCH A;  1WMW A;  2DH4 A;  5JUZ F;  3M9U A;  5B02 A;  2PS8 A;  4KUX A;  1VG7 A;  2PS6 A;  3SDQ A;  1WL3 A;  5IL3 A;  4LIX A;  1V4E A;  3LDW A;  1RTR A;  2AZL A;  2E94 A;  3ACY A;  5AHU B;  5DHK A;  5IK6 A;  2OPM A;  3W7F A;  3IBA A;  4NFK F;  1JFA A;  1V4J A;  4LZC A;  3RMG A;  3AQ0 A;  3WSB A;  1JFG A;  4KQU A;  1EZF A;  5B0K A;  5JV0 F;  1HX9 A;  1UBY A;  4LLS A;  1UBV A;  4DWB A;  3VJC A;  3M0G A;  3CKE A;  4GAX A;  3LEE A;  1RQI A;  4RXC A;  4DHD A;  5AEL A;  3EZ3 A;  5JA0 F;  3WJK A;  3KBK A;  4LTV A;  4F62 A;  5B03 A;  5B0I A;  1KIY A;  3MZV A;  1UBW A;  2E90 A;  5B0M A;  2J1O A;  4P0X A;  1VG2 A;  1HXA A;  2PS5 A;  5AYP A;  5B00 A;  3LMD A;  3S4J A;  2Z78 A;  4OMG A;  4N1Z F;  5JV2 F;  3OAC A;  5CG5 A;  4XQR F;  5IM1 A;  4PVX F;  3RYW A;  3KRF A;  3WCF A;  5B01 A;  2Z52 A;  3P8L A;  4RNQ A;  1FPS A;  3NPK A;  2Q80 A;  2AEK A;  3KRC B;  3KRP A;  4KKM A;  2H8O A;  3ZCD A;  1YYQ A;  2PS7 A;  1WKZ A;  3M02 A;  4FJQ A;  3WCD A;  2I19 A;  4GP1 A;  2E93 A;  5IKA A;  4KPD A;  3N5H F;  5HNA A;  2O1O A;  2QIS A;  4Q23 A;  2F9K F;  4DZW A;  3WE9 A;  1V4K A;  3KB9 A;  3AE0 A;  3ZMC A;  5E8H A;  3QQV A;  4JZB A;  3APZ A;  4KWD A;  3RYE A;  3V1X A;  1VG4 A;  3N49 F;  5DGM F;  4MC0 A;  2Q9Z A;  2Z4W A;  3ICZ A;  5EAS A;  5AFX A;  3ZOU A;  3SAE A;  4UMJ A;  4LA6 A;  3ZMB A;  5HN8 A;  3G4D A;  1N1Z A;  1VG6 A;  5ER8 A;  3N45 F;  3WC9 A;  1PS1 A;  3LGK A;  1YYS A;  3WJN A;  4RXA A;  5ILI A;  1YQ7 A;  3OAB B;  4NKF A;  1YV5 A;  1YYU A;  4LOB A;  3CC9 A;  4F6V A;  5ERN A;  3M01 A;  3N6K F;  3SDU A;  5A0J A;  5B0L A;  4JYX A;  1WY0 A;  3SDT A;  1N1B A;  2EWG A;  3BNY A;  2ONG A;  2E4O A;  5IVG A;  3KRF B;  4JVJ F;  5C05 A;  2J5C A;  2FOR A;  3NPR A;  3KRA A;  2E8V A;  1DGP A;  3KRP B;  4E9U A;  2E95 A;  3OYR A;  2OA6 A;  4LFG A;  5ILH A;  3WEJ A;  3EFQ A;  5E8K A;  4JXY A;  4RXE A;  3LLW A;  4MC8 A;  4DXJ A;  5I1U A;  3NRI A;  1RQJ A;  4E1E A;  2E92 A;  5EAT A;  1V4H A;  3QKC A;  2F94 F;  1ZW5 A;  4EA2 A;  3N0G A;  4JXN A;  4KPJ A;  4OGU A;  3WEG A;  5HN7 A;  3LVS A;  3WCG A;  4DI5 A;  3ADZ A;  3ACX A;  3WCI A;  3WCC A;  3WCB A;  2ZCR A;  3N1V F;  4H5E F;  5A0I A;  3WJO A;  1HM7 A;  2F7M F;  5IN8 A;  3P5P A;  3N46 F;  2ZCO A;  5IMN A;  3M00 A;  3VJ8 A;  4RYP A;  2Q9Y A;  4LA5 A;  5E8L A;  2Z7H A;  3N3D A;  4NUA A;  1DI1 A;  2F8Z F;  4H5C F;  3TFN A;  4LZ0 A;  4LPH F;  3N5J F;  1N23 A;  2ZCS A;  1HXG A;  3LG5 A;  4EA1 A;  5ILJ A;  1KIZ A;  1VG3 A;  3Q1O A;  2E8U A;  5B0J A;  3DYH A;  4GA3 A;  4OMH A;  4KQ5 A;  3SDV A;  3WSA A;  3VJD A;  3SDR A;  2F8C F;  5DJP F;  3ICM A;  5IKH A;  4KVD A;  2E8X A;  3BNX A;  3KRA B;  3WCM A;  4LLT A;  3WCJ A;  4FP4 A;  5CG6 A;  5DGN F;  5IMP A;  3TFV A;  4OKM A;  4MC3 A;  2Z4Y A;  3ZL6 A;  3AQB B;  5DHI A;  3ASX A;  4LTZ A;  4K10 A;  3S9V A;  3P41 A;  3PYB A;  4XQT F;  5KSX F;  4KQS A;  2PS4 A;  4KVY A;  4NFJ F;  3LSN A;  3Q2Z A;  5DZ2 A;  2Z4X A;  5HN9 A;  3ACW A;  1YYT A;  4P0W A;  4L2X F;  4P0V A;  1YHM A;  3OAC B;  3TC1 A;  2E8W A;  4KFA A;  3LOM A;  3KRO A;  4LUU A;  5IL8 A;  3LK5 A;  5H9D A;  3LZ9 A;  3P8R A;  5ILY A;  4QXS F; 
#chains in the Genus database with same CATH homology
 2OGD A;  5IK0 A;  1HM4 A;  4LZ3 A;  4OKZ A;  3KRC A;  4NG6 A;  2ZEU A;  2ZCQ A;  2FTZ A;  4F6X A;  3LJI A;  4NFI F;  4XQS F;  5JV1 F;  3IPI A;  4RXD A;  3VJB A;  2E91 A;  4LFV F;  4KVW A;  3DYG A;  4LFE A;  1V4I A;  5DW7 A;  3PH7 A;  2Z4Z A;  3WEH A;  4ZQ8 A;  3VJE A;  1YHL A;  5ERO A;  3ICN A;  3WCA A;  4HD1 A;  2Z7I A;  5DJV F;  3EGT A;  4KVI A;  3G4F A;  4DEM F;  3Q2Q A;  3B7L A;  3OAB A;  3N3L F;  3WEF A;  3DYF A;  3PYA A;  3VJA A;  4NKE A;  3TFP A;  3WEI A;  1N20 A;  3RBM A;  5ILD A;  4LPG F;  2AEL A;  1YYR A;  2AET A;  3ID0 A;  3LGZ B;  3V66 A;  2ZEV A;  5ERM A;  5EAU A;  2ONH A;  2F92 F;  2Q58 A;  3KRO B;  1WL2 A;  2Z50 A;  3V1V A;  5IK9 A;  5DJR F;  2J1P A;  4JZX A;  5DGS F;  4N9U A;  2AZJ A;  1WL0 A;  2E8T A;  3WCE A;  4PVY F;  5IMI A;  3AQC B;  2AZK A;  4GP2 A;  3WCL A;  3MAV A;  5DIQ F;  4E9Z A;  5ILK A;  3CP6 A;  1YJ4 A;  4QPF A;  2ZY1 A;  2F89 F;  3NF2 A;  4H5D F;  4LXW A;  4DWG A;  3N1W F;  1HXC A;  5ILZ A;  2P1C A;  3PKO A;  3VJ9 A;  3N0F A;  5A0K A;  1YHK A;  1N22 A;  2OPN A;  3P5R A;  2Z4V A;  3Q30 A;  2VF6 A;  1WL1 A;  1UBX A;  3UCA A;  1N21 A;  3PDE A;  4WK5 A;  1N24 A;  2RAH A;  4EA0 A;  3ICK A;  4KK2 A;  3WEK A;  3TS7 A;  3WCH A;  1WMW A;  2DH4 A;  5JUZ F;  3M9U A;  5B02 A;  2PS8 A;  4KUX A;  1VG7 A;  2PS6 A;  3SDQ A;  1WL3 A;  5IL3 A;  4LIX A;  1V4E A;  3LDW A;  1RTR A;  2AZL A;  2E94 A;  3ACY A;  5AHU B;  5DHK A;  5IK6 A;  2OPM A;  3W7F A;  3IBA A;  4NFK F;  1JFA A;  1V4J A;  4LZC A;  3RMG A;  3AQ0 A;  3WSB A;  1JFG A;  4KQU A;  1EZF A;  5B0K A;  5JV0 F;  1HX9 A;  1UBY A;  4LLS A;  1UBV A;  4DWB A;  3VJC A;  3M0G A;  3CKE A;  4GAX A;  3LEE A;  1RQI A;  4RXC A;  4DHD A;  5AEL A;  3EZ3 A;  5JA0 F;  3WJK A;  3KBK A;  4LTV A;  4F62 A;  5B03 A;  5B0I A;  1KIY A;  3MZV A;  1UBW A;  2E90 A;  5B0M A;  2J1O A;  4P0X A;  1VG2 A;  1HXA A;  2PS5 A;  5AYP A;  5B00 A;  3LMD A;  3S4J A;  2Z78 A;  4OMG A;  4N1Z F;  5JV2 F;  3OAC A;  5CG5 A;  4XQR F;  5IM1 A;  4PVX F;  3RYW A;  3KRF A;  3WCF A;  5B01 A;  2Z52 A;  3P8L A;  4RNQ A;  1FPS A;  3NPK A;  2Q80 A;  2AEK A;  3KRC B;  3KRP A;  4KKM A;  2H8O A;  3ZCD A;  1YYQ A;  2PS7 A;  1WKZ A;  3M02 A;  4FJQ A;  3WCD A;  2I19 A;  4GP1 A;  2E93 A;  5IKA A;  4KPD A;  3N5H F;  5HNA A;  2O1O A;  2QIS A;  4Q23 A;  2F9K F;  4DZW A;  3WE9 A;  1V4K A;  3KB9 A;  3AE0 A;  3ZMC A;  5E8H A;  3QQV A;  4JZB A;  3APZ A;  4KWD A;  3RYE A;  3V1X A;  1VG4 A;  3N49 F;  5DGM F;  4MC0 A;  2Q9Z A;  2Z4W A;  3ICZ A;  5EAS A;  5AFX A;  3ZOU A;  3SAE A;  4UMJ A;  4LA6 A;  3ZMB A;  5HN8 A;  3G4D A;  1N1Z A;  1VG6 A;  5ER8 A;  3N45 F;  3WC9 A;  1PS1 A;  3LGK A;  1YYS A;  3WJN A;  4RXA A;  5ILI A;  1YQ7 A;  3OAB B;  4NKF A;  1YV5 A;  1YYU A;  4LOB A;  3CC9 A;  4F6V A;  5ERN A;  3M01 A;  3N6K F;  3SDU A;  5A0J A;  5B0L A;  4JYX A;  1WY0 A;  3SDT A;  1N1B A;  2EWG A;  3BNY A;  2ONG A;  2E4O A;  5IVG A;  3KRF B;  4JVJ F;  5C05 A;  2J5C A;  2FOR A;  3NPR A;  3KRA A;  2E8V A;  1DGP A;  3KRP B;  4E9U A;  2E95 A;  3OYR A;  2OA6 A;  4LFG A;  5ILH A;  3WEJ A;  3EFQ A;  5E8K A;  4JXY A;  4RXE A;  3LLW A;  4MC8 A;  4DXJ A;  5I1U A;  3NRI A;  1RQJ A;  4E1E A;  2E92 A;  5EAT A;  1V4H A;  3QKC A;  2F94 F;  1ZW5 A;  4EA2 A;  3N0G A;  4JXN A;  4KPJ A;  4OGU A;  3WEG A;  5HN7 A;  3LVS A;  3WCG A;  4DI5 A;  3ADZ A;  3ACX A;  3WCI A;  3WCC A;  3WCB A;  2ZCR A;  3N1V F;  4H5E F;  5A0I A;  3WJO A;  1HM7 A;  2F7M F;  5IN8 A;  3P5P A;  3N46 F;  2ZCO A;  5IMN A;  3M00 A;  3VJ8 A;  4RYP A;  2Q9Y A;  4LA5 A;  5E8L A;  2Z7H A;  3N3D A;  4NUA A;  1DI1 A;  2F8Z F;  4H5C F;  3TFN A;  4LZ0 A;  4LPH F;  3N5J F;  1N23 A;  2ZCS A;  1HXG A;  3LG5 A;  4EA1 A;  5ILJ A;  1KIZ A;  1VG3 A;  3Q1O A;  2E8U A;  5B0J A;  3DYH A;  4GA3 A;  4OMH A;  4KQ5 A;  3SDV A;  3WSA A;  3VJD A;  3SDR A;  2F8C F;  5DJP F;  3ICM A;  5IKH A;  4KVD A;  2E8X A;  3BNX A;  3KRA B;  3WCM A;  4LLT A;  3WCJ A;  4FP4 A;  5CG6 A;  5DGN F;  5IMP A;  3TFV A;  4OKM A;  4MC3 A;  2Z4Y A;  3ZL6 A;  3AQB B;  5DHI A;  3ASX A;  4LTZ A;  4K10 A;  3S9V A;  3P41 A;  3PYB A;  4XQT F;  5KSX F;  4KQS A;  2PS4 A;  4KVY A;  4NFJ F;  3LSN A;  3Q2Z A;  5DZ2 A;  2Z4X A;  5HN9 A;  3ACW A;  1YYT A;  4P0W A;  4L2X F;  4P0V A;  1YHM A;  3OAC B;  3TC1 A;  2E8W A;  4KFA A;  3LOM A;  3KRO A;  4LUU A;  5IL8 A;  3LK5 A;  5H9D A;  3LZ9 A;  3P8R A;  5ILY A;  4QXS F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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