4PVYF

Crystal structure of human fpps in complex with [({5-[4-(propan-2-yloxy)phenyl]pyridin-3-yl}amino)methanediyl]bis(phosphonic acid)
Total Genus 140
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
140
sequence length
346
structure length
346
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
molecule keywords Farnesyl pyrophosphate synthase
publication title Crystallographic and thermodynamic characterization of phenylaminopyridine bisphosphonates binding to human farnesyl pyrophosphate synthase.
pubmed doi rcsb
source organism Homo sapiens
total genus 140
structure length 346
sequence length 346
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2014-03-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4pvyF00
3DYHA 4LPHF 3ICMA 1WL0A 4KK2A 5B0MA 3SDTA 3V1XA 2E8TA 2Z4YA 3LSNA 2ZY1A 3WCAA 2F8CF 2O1OA 5E8HA 2RAHA 4XQRF 2E8XA 3SAEA 3N46F 3OABA 4RXAA 4DHDA 1RQIA 5DJPF 3LLWA 3N0GA 4KVYA 3ID0A 1V4IA 3P8LA 4LZCA 5ERNA 4PVXF 1N22A 2J5CA 2F92F 4LTZA 4KVWA 5C05A 2AEKA 3LVSA 4EA2A 2Z50A 3SDQA 3N0FA 1UBVA 4JZXA 4XQSF 3WEJA 3PKOA 5DJVF 5ILIA 3WEGA 2E94A 5ILYA 2PS8A 2AZLA 3LOMA 4H5EF 4H5DF 5B01A 3M9UA 3NPRA 2ZCRA 1UBWA 2Q80A 1UBYA 3WSBA 5HNAA 2J1OA 3ACXA 2Q58A 5EROA 5B0IA 3LMDA 3B7LA 4KVIA 1HXAA 3WCDA 3DYFA 4RXEA 3AQCB 3TFNA 3N5HF 1DI1A 4LFGA 1RTRA 3M01A 5ER8A 3M00A 4DXJA 2E90A 2ZEUA 3IPIA 3Q30A 3VJAA 4XQTF 3NRIA 4OKZA 3ZL6A 3QQVA 4HD1A 3WC9A 5ILKA 5IMNA 4KPJA 4LUUA 1N20A 1VG6A 2PS6A 5AELA 3AQBB 4H5CF 4LLTA 3WCLA 4F6XA 1EZFA 3W7FA 3WCMA 3OACA 3KRFB 3KRPB 1PS1A 3NF2A 4OMHA 2Z7HA 5DHIA 3WJKA 1WL1A 4GA3A 1N23A 4JYXA 1YYUA 2OA6A 4LTVA 3WCFA 1YJ4A 3CC9A 2E8UA 1HX9A 3PDEA 1KIZA 3MAVA 4MC8A 3SDVA 4DWBA 5EASA 3LG5A 3PH7A 3V1VA 5KSXF 2QISA 5IVGA 3VJDA 4E9UA 3ACYA 3WCHA 3KBKA 2OPMA 3EFQA 3G4DA 4KFAA 2OPNA 3M02A 4NFJF 1N24A 3N1WF 3ICZA 4Q23A 1V4KA 2Z4XA 3ICKA 3KRAB 4LPGF 2AZJA 5IKAA 3S9VA 3P5PA 3N49F 3Q1OA 3LJIA 4GAXA 3KRCB 4LA5A 1ZW5A 3TFVA 5HN8A 5IMPA 2FORA 5AFXA 4DZWA 1UBXA 5DGMF 4RXDA 5IM1A 3P5RA 1VG4A 1YYQA 5ILJA 5IMIA 3BNXA 2AETA 3V66A 3ICNA 4RYPA 5DJRF 3WEHA 4DWGA 5JV0F 5B0JA 3WE9A 5IK0A 3N1VF 4OGUA 2F9KF 5DHKA 3Q2ZA 5IK9A 1WKZA 2Z7IA 1YYTA 3WCBA 4E9ZA 4JZBA 1HXCA 4KQ5A 1V4EA 3N6KF 3KROB 1YHMA 3OACB 1JFGA 3QKCA 4LFVF 4LIXA 3ACWA 3LDWA 2Z4ZA 3AQ0A 3OYRA 2F89F 5ILZA 4P0WA 5AYPA 4F62A 4KUXA 4FJQA 1V4HA 3WCIA 3ASXA 1FPSA 2P1CA 3LK5A 5HN9A 1N21A 2E93A 3VJ8A 3KB9A 3TFPA 1YHLA 1N1BA 3LGZB 3P41A 4LXWA 3ZCDA 3PYAA 3DYGA 3VJCA 3ZOUA 4P0VA 3N45F 4LFEA 4LA6A 1HM4A 4EA0A 4OMGA 5DW7A 5IKHA 3RMGA 3BNYA 3CKEA 3N3DA 4LZ0A 3RBMA 1JFAA 3N5JF 4L2XF 4LZ3A 3WJOA 3LZ9A 3G4FA 5DGSF 2F94F 3MZVA 5EAUA 1YYSA 3OABB 3WCGA 2F8ZF 1N1ZA 5JV2F 3TS7A 5H9DA 5B0LA 5A0JA 4KQUA 3S4JA 4OKMA 1HM7A 3KRFA 3KRPA 5ILHA 4F6VA 1HXGA 5E8LA 2AZKA 2EWGA 2E8VA 1YQ7A 1WL2A 5HN7A 1RQJA 2Q9ZA 4N1ZF 5JV1F 3LEEA 5IK6A 4JXYA 5JUZF 2ONGA 5ERMA 3WEKA 3WEFA 4LOBA 4GP1A 2I19A 1WMWA 2E95A 5EATA 2PS5A 5CG6A 4MC0A 3TC1A 4NKEA 1WY0A 5CG5A 3VJ9A 3Q2QA 5AHUB 4KQSA 3ADZA 2E91A 3AE0A 3IBAA 1VG3A 4UMJA 3KRAA 5DZ2A 1YV5A 3SDRA 5JA0F 2E92A 2ONHA 2FTZA 4QXSF 2AELA 3M0GA 3UCAA 5B03A 3P8RA 4P0XA 3KRCA 3WCCA 2Z4WA 3LGKA 3NPKA 1VG2A 2Z4VA 4PVYF 3PYBA 1YYRA 3VJEA 1YHKA 4ZQ8A 3ZMBA 1WL3A 4NUAA 4RXCA 4LLSA 4KWDA 2PS4A 5IL8A 2H8OA 1V4JA 4JXNA 5A0KA 2F7MF 5ILDA 5B0KA 4NKFA 5IN8A 3ZMCA 2PS7A 5B02A 3EZ3A 4NFIF 2VF6A 3SDUA 2Z52A 3KROA 4DEMF 1VG7A 4QPFA 5B00A 3WCEA 2OGDA 4N9UA 2ZCSA 3APZA 1DGPA 4RNQA 4EA1A 2E4OA 2ZEVA 4JVJF 4NFKF 4WK5A 5A0IA 4FP4A 2Q9YA 4GP2A 5IL3A 1KIYA 4K10A 2E8WA 4E1EA 2DH4A 5DIQF 3RYEA 3WEIA 5E8KA 2Z78A 2ZCQA 3EGTA 3WSAA 4KVDA 3VJBA 4NG6A 5DGNF 3CP6A 3WJNA 4KKMA 2J1PA 2ZCOA 3RYWA 4KPDA 3WCJA 4DI5A 3N3LF 4MC3A 5I1UA
chains in the Genus database with same CATH superfamily
3DYHA 4LPHF 3ICMA 1WL0A 4KK2A 5B0MA 3SDTA 3V1XA 2E8TA 2Z4YA 3LSNA 2ZY1A 3WCAA 2F8CF 2O1OA 5E8HA 2RAHA 4XQRF 2E8XA 3SAEA 3N46F 3OABA 4RXAA 4DHDA 1RQIA 5DJPF 3LLWA 3N0GA 4KVYA 3ID0A 1V4IA 3P8LA 4LZCA 5ERNA 4PVXF 1N22A 2J5CA 2F92F 4LTZA 4KVWA 5C05A 2AEKA 3LVSA 4EA2A 2Z50A 3SDQA 3N0FA 1UBVA 4JZXA 4XQSF 3WEJA 3PKOA 5DJVF 5ILIA 3WEGA 2E94A 5ILYA 2PS8A 2AZLA 3LOMA 4H5EF 4H5DF 5B01A 3M9UA 3NPRA 2ZCRA 1UBWA 2Q80A 1UBYA 3WSBA 5HNAA 2J1OA 3ACXA 2Q58A 5EROA 5B0IA 3LMDA 3B7LA 4KVIA 1HXAA 3WCDA 3DYFA 4RXEA 3AQCB 3TFNA 3N5HF 1DI1A 4LFGA 1RTRA 3M01A 5ER8A 3M00A 4DXJA 2E90A 2ZEUA 3IPIA 3Q30A 3VJAA 4XQTF 3NRIA 4OKZA 3ZL6A 3QQVA 4HD1A 3WC9A 5ILKA 5IMNA 4KPJA 4LUUA 1N20A 1VG6A 2PS6A 5AELA 3AQBB 4H5CF 4LLTA 3WCLA 4F6XA 1EZFA 3W7FA 3WCMA 3OACA 3KRFB 3KRPB 1PS1A 3NF2A 4OMHA 2Z7HA 5DHIA 3WJKA 1WL1A 4GA3A 1N23A 4JYXA 1YYUA 2OA6A 4LTVA 3WCFA 1YJ4A 3CC9A 2E8UA 1HX9A 3PDEA 1KIZA 3MAVA 4MC8A 3SDVA 4DWBA 5EASA 3LG5A 3PH7A 3V1VA 5KSXF 2QISA 5IVGA 3VJDA 4E9UA 3ACYA 3WCHA 3KBKA 2OPMA 3EFQA 3G4DA 4KFAA 2OPNA 3M02A 4NFJF 1N24A 3N1WF 3ICZA 4Q23A 1V4KA 2Z4XA 3ICKA 3KRAB 4LPGF 2AZJA 5IKAA 3S9VA 3P5PA 3N49F 3Q1OA 3LJIA 4GAXA 3KRCB 4LA5A 1ZW5A 3TFVA 5HN8A 5IMPA 2FORA 5AFXA 4DZWA 1UBXA 5DGMF 4RXDA 5IM1A 3P5RA 1VG4A 1YYQA 5ILJA 5IMIA 3BNXA 2AETA 3V66A 3ICNA 4RYPA 5DJRF 3WEHA 4DWGA 5JV0F 5B0JA 3WE9A 5IK0A 3N1VF 4OGUA 2F9KF 5DHKA 3Q2ZA 5IK9A 1WKZA 2Z7IA 1YYTA 3WCBA 4E9ZA 4JZBA 1HXCA 4KQ5A 1V4EA 3N6KF 3KROB 1YHMA 3OACB 1JFGA 3QKCA 4LFVF 4LIXA 3ACWA 3LDWA 2Z4ZA 3AQ0A 3OYRA 2F89F 5ILZA 4P0WA 5AYPA 4F62A 4KUXA 4FJQA 1V4HA 3WCIA 3ASXA 1FPSA 2P1CA 3LK5A 5HN9A 1N21A 2E93A 3VJ8A 3KB9A 3TFPA 1YHLA 1N1BA 3LGZB 3P41A 4LXWA 3ZCDA 3PYAA 3DYGA 3VJCA 3ZOUA 4P0VA 3N45F 4LFEA 4LA6A 1HM4A 4EA0A 4OMGA 5DW7A 5IKHA 3RMGA 3BNYA 3CKEA 3N3DA 4LZ0A 3RBMA 1JFAA 3N5JF 4L2XF 4LZ3A 3WJOA 3LZ9A 3G4FA 5DGSF 2F94F 3MZVA 5EAUA 1YYSA 3OABB 3WCGA 2F8ZF 1N1ZA 5JV2F 3TS7A 5H9DA 5B0LA 5A0JA 4KQUA 3S4JA 4OKMA 1HM7A 3KRFA 3KRPA 5ILHA 4F6VA 1HXGA 5E8LA 2AZKA 2EWGA 2E8VA 1YQ7A 1WL2A 5HN7A 1RQJA 2Q9ZA 4N1ZF 5JV1F 3LEEA 5IK6A 4JXYA 5JUZF 2ONGA 5ERMA 3WEKA 3WEFA 4LOBA 4GP1A 2I19A 1WMWA 2E95A 5EATA 2PS5A 5CG6A 4MC0A 3TC1A 4NKEA 1WY0A 5CG5A 3VJ9A 3Q2QA 5AHUB 4KQSA 3ADZA 2E91A 3AE0A 3IBAA 1VG3A 4UMJA 3KRAA 5DZ2A 1YV5A 3SDRA 5JA0F 2E92A 2ONHA 2FTZA 4QXSF 2AELA 3M0GA 3UCAA 5B03A 3P8RA 4P0XA 3KRCA 3WCCA 2Z4WA 3LGKA 3NPKA 1VG2A 2Z4VA 4PVYF 3PYBA 1YYRA 3VJEA 1YHKA 4ZQ8A 3ZMBA 1WL3A 4NUAA 4RXCA 4LLSA 4KWDA 2PS4A 5IL8A 2H8OA 1V4JA 4JXNA 5A0KA 2F7MF 5ILDA 5B0KA 4NKFA 5IN8A 3ZMCA 2PS7A 5B02A 3EZ3A 4NFIF 2VF6A 3SDUA 2Z52A 3KROA 4DEMF 1VG7A 4QPFA 5B00A 3WCEA 2OGDA 4N9UA 2ZCSA 3APZA 1DGPA 4RNQA 4EA1A 2E4OA 2ZEVA 4JVJF 4NFKF 4WK5A 5A0IA 4FP4A 2Q9YA 4GP2A 5IL3A 1KIYA 4K10A 2E8WA 4E1EA 2DH4A 5DIQF 3RYEA 3WEIA 5E8KA 2Z78A 2ZCQA 3EGTA 3WSAA 4KVDA 3VJBA 4NG6A 5DGNF 3CP6A 3WJNA 4KKMA 2J1PA 2ZCOA 3RYWA 4KPDA 3WCJA 4DI5A 3N3LF 4MC3A 5I1UA
chains in the Genus database with same CATH topology
3DYHA 4LPHF 3ICMA 1WL0A 4KK2A 5B0MA 3SDTA 3V1XA 2E8TA 2Z4YA 3LSNA 2ZY1A 3WCAA 2F8CF 2O1OA 5E8HA 2RAHA 4XQRF 2E8XA 3SAEA 3N46F 3OABA 4RXAA 4DHDA 1RQIA 5DJPF 3LLWA 3N0GA 4KVYA 3ID0A 1V4IA 3P8LA 4LZCA 5ERNA 4PVXF 1N22A 2J5CA 2F92F 4LTZA 4KVWA 5C05A 2AEKA 3LVSA 4EA2A 2Z50A 3SDQA 3N0FA 1UBVA 4JZXA 4XQSF 3WEJA 3PKOA 5DJVF 5ILIA 3WEGA 2E94A 5ILYA 2PS8A 2AZLA 3LOMA 4H5EF 4H5DF 5B01A 3M9UA 3NPRA 2ZCRA 1UBWA 2Q80A 1UBYA 3WSBA 5HNAA 2J1OA 3ACXA 2Q58A 5EROA 5B0IA 3LMDA 3B7LA 4KVIA 1HXAA 3WCDA 3DYFA 4RXEA 3AQCB 3TFNA 3N5HF 1DI1A 4LFGA 1RTRA 3M01A 5ER8A 3M00A 4DXJA 2E90A 2ZEUA 3IPIA 3Q30A 3VJAA 4XQTF 3NRIA 4OKZA 3ZL6A 3QQVA 4HD1A 3WC9A 5ILKA 5IMNA 4KPJA 4LUUA 1N20A 1VG6A 2PS6A 5AELA 3AQBB 4H5CF 4LLTA 3WCLA 4F6XA 1EZFA 3W7FA 3WCMA 3OACA 3KRFB 3KRPB 1PS1A 3NF2A 4OMHA 2Z7HA 5DHIA 3WJKA 1WL1A 4GA3A 1N23A 4JYXA 1YYUA 2OA6A 4LTVA 3WCFA 1YJ4A 3CC9A 2E8UA 1HX9A 3PDEA 1KIZA 3MAVA 4MC8A 3SDVA 4DWBA 5EASA 3LG5A 3PH7A 3V1VA 5KSXF 2QISA 5IVGA 3VJDA 4E9UA 3ACYA 3WCHA 3KBKA 2OPMA 3EFQA 3G4DA 4KFAA 2OPNA 3M02A 4NFJF 1N24A 3N1WF 3ICZA 4Q23A 1V4KA 2Z4XA 3ICKA 3KRAB 4LPGF 2AZJA 5IKAA 3S9VA 3P5PA 3N49F 3Q1OA 3LJIA 4GAXA 3KRCB 4LA5A 1ZW5A 3TFVA 5HN8A 5IMPA 2FORA 5AFXA 4DZWA 1UBXA 5DGMF 4RXDA 5IM1A 3P5RA 1VG4A 1YYQA 5ILJA 5IMIA 3BNXA 2AETA 3V66A 3ICNA 4RYPA 5DJRF 3WEHA 4DWGA 5JV0F 5B0JA 3WE9A 5IK0A 3N1VF 4OGUA 2F9KF 5DHKA 3Q2ZA 5IK9A 1WKZA 2Z7IA 1YYTA 3WCBA 4E9ZA 4JZBA 1HXCA 4KQ5A 1V4EA 3N6KF 3KROB 1YHMA 3OACB 1JFGA 3QKCA 4LFVF 4LIXA 3ACWA 3LDWA 2Z4ZA 3AQ0A 3OYRA 2F89F 5ILZA 4P0WA 5AYPA 4F62A 4KUXA 4FJQA 1V4HA 3WCIA 3ASXA 1FPSA 2P1CA 3LK5A 5HN9A 1N21A 2E93A 3VJ8A 3KB9A 3TFPA 1YHLA 1N1BA 3LGZB 3P41A 4LXWA 3ZCDA 3PYAA 3DYGA 3VJCA 3ZOUA 4P0VA 3N45F 4LFEA 4LA6A 1HM4A 4EA0A 4OMGA 5DW7A 5IKHA 3RMGA 3BNYA 3CKEA 3N3DA 4LZ0A 3RBMA 1JFAA 3N5JF 4L2XF 4LZ3A 3WJOA 3LZ9A 3G4FA 5DGSF 2F94F 3MZVA 5EAUA 1YYSA 3OABB 3WCGA 2F8ZF 1N1ZA 5JV2F 3TS7A 5H9DA 5B0LA 5A0JA 4KQUA 3S4JA 4OKMA 1HM7A 3KRFA 3KRPA 5ILHA 4F6VA 1HXGA 5E8LA 2AZKA 2EWGA 2E8VA 1YQ7A 1WL2A 5HN7A 1RQJA 2Q9ZA 4N1ZF 5JV1F 3LEEA 5IK6A 4JXYA 5JUZF 2ONGA 5ERMA 3WEKA 3WEFA 4LOBA 4GP1A 2I19A 1WMWA 2E95A 5EATA 2PS5A 5CG6A 4MC0A 3TC1A 4NKEA 1WY0A 5CG5A 3VJ9A 3Q2QA 5AHUB 4KQSA 3ADZA 2E91A 3AE0A 3IBAA 1VG3A 4UMJA 3KRAA 5DZ2A 1YV5A 3SDRA 5JA0F 2E92A 2ONHA 2FTZA 4QXSF 2AELA 3M0GA 3UCAA 5B03A 3P8RA 4P0XA 3KRCA 3WCCA 2Z4WA 3LGKA 3NPKA 1VG2A 2Z4VA 4PVYF 3PYBA 1YYRA 3VJEA 1YHKA 4ZQ8A 3ZMBA 1WL3A 4NUAA 4RXCA 4LLSA 4KWDA 2PS4A 5IL8A 2H8OA 1V4JA 4JXNA 5A0KA 2F7MF 5ILDA 5B0KA 4NKFA 5IN8A 3ZMCA 2PS7A 5B02A 3EZ3A 4NFIF 2VF6A 3SDUA 2Z52A 3KROA 4DEMF 1VG7A 4QPFA 5B00A 3WCEA 2OGDA 4N9UA 2ZCSA 3APZA 1DGPA 4RNQA 4EA1A 2E4OA 2ZEVA 4JVJF 4NFKF 4WK5A 5A0IA 4FP4A 2Q9YA 4GP2A 5IL3A 1KIYA 4K10A 2E8WA 4E1EA 2DH4A 5DIQF 3RYEA 3WEIA 5E8KA 2Z78A 2ZCQA 3EGTA 3WSAA 4KVDA 3VJBA 4NG6A 5DGNF 3CP6A 3WJNA 4KKMA 2J1PA 2ZCOA 3RYWA 4KPDA 3WCJA 4DI5A 3N3LF 4MC3A 5I1UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DYH A;  4LPH F;  3ICM A;  1WL0 A;  4KK2 A;  5B0M A;  3SDT A;  3V1X A;  2E8T A;  2Z4Y A;  3LSN A;  2ZY1 A;  3WCA A;  2F8C F;  2O1O A;  5E8H A;  2RAH A;  4XQR F;  2E8X A;  3SAE A;  3N46 F;  3OAB A;  4RXA A;  4DHD A;  1RQI A;  5DJP F;  3LLW A;  3N0G A;  4KVY A;  3ID0 A;  1V4I A;  3P8L A;  4LZC A;  5ERN A;  4PVX F;  1N22 A;  2J5C A;  2F92 F;  4LTZ A;  4KVW A;  5C05 A;  2AEK A;  3LVS A;  4EA2 A;  2Z50 A;  3SDQ A;  3N0F A;  1UBV A;  4JZX A;  4XQS F;  3WEJ A;  3PKO A;  5DJV F;  5ILI A;  3WEG A;  2E94 A;  5ILY A;  2PS8 A;  2AZL A;  3LOM A;  4H5E F;  4H5D F;  5B01 A;  3M9U A;  3NPR A;  2ZCR A;  1UBW A;  2Q80 A;  1UBY A;  3WSB A;  5HNA A;  2J1O A;  3ACX A;  2Q58 A;  5ERO A;  5B0I A;  3LMD A;  3B7L A;  4KVI A;  1HXA A;  3WCD A;  3DYF A;  4RXE A;  3AQC B;  3TFN A;  3N5H F;  1DI1 A;  4LFG A;  1RTR A;  3M01 A;  5ER8 A;  3M00 A;  4DXJ A;  2E90 A;  2ZEU A;  3IPI A;  3Q30 A;  3VJA A;  4XQT F;  3NRI A;  4OKZ A;  3ZL6 A;  3QQV A;  4HD1 A;  3WC9 A;  5ILK A;  5IMN A;  4KPJ A;  4LUU A;  1N20 A;  1VG6 A;  2PS6 A;  5AEL A;  3AQB B;  4H5C F;  4LLT A;  3WCL A;  4F6X A;  1EZF A;  3W7F A;  3WCM A;  3OAC A;  3KRF B;  3KRP B;  1PS1 A;  3NF2 A;  4OMH A;  2Z7H A;  5DHI A;  3WJK A;  1WL1 A;  4GA3 A;  1N23 A;  4JYX A;  1YYU A;  2OA6 A;  4LTV A;  3WCF A;  1YJ4 A;  3CC9 A;  2E8U A;  1HX9 A;  3PDE A;  1KIZ A;  3MAV A;  4MC8 A;  3SDV A;  4DWB A;  5EAS A;  3LG5 A;  3PH7 A;  3V1V A;  5KSX F;  2QIS A;  5IVG A;  3VJD A;  4E9U A;  3ACY A;  3WCH A;  3KBK A;  2OPM A;  3EFQ A;  3G4D A;  4KFA A;  2OPN A;  3M02 A;  4NFJ F;  1N24 A;  3N1W F;  3ICZ A;  4Q23 A;  1V4K A;  2Z4X A;  3ICK A;  3KRA B;  4LPG F;  2AZJ A;  5IKA A;  3S9V A;  3P5P A;  3N49 F;  3Q1O A;  3LJI A;  4GAX A;  3KRC B;  4LA5 A;  1ZW5 A;  3TFV A;  5HN8 A;  5IMP A;  2FOR A;  5AFX A;  4DZW A;  1UBX A;  5DGM F;  4RXD A;  5IM1 A;  3P5R A;  1VG4 A;  1YYQ A;  5ILJ A;  5IMI A;  3BNX A;  2AET A;  3V66 A;  3ICN A;  4RYP A;  5DJR F;  3WEH A;  4DWG A;  5JV0 F;  5B0J A;  3WE9 A;  5IK0 A;  3N1V F;  4OGU A;  2F9K F;  5DHK A;  3Q2Z A;  5IK9 A;  1WKZ A;  2Z7I A;  1YYT A;  3WCB A;  4E9Z A;  4JZB A;  1HXC A;  4KQ5 A;  1V4E A;  3N6K F;  3KRO B;  1YHM A;  3OAC B;  1JFG A;  3QKC A;  4LFV F;  4LIX A;  3ACW A;  3LDW A;  2Z4Z A;  3AQ0 A;  3OYR A;  2F89 F;  5ILZ A;  4P0W A;  5AYP A;  4F62 A;  4KUX A;  4FJQ A;  1V4H A;  3WCI A;  3ASX A;  1FPS A;  2P1C A;  3LK5 A;  5HN9 A;  1N21 A;  2E93 A;  3VJ8 A;  3KB9 A;  3TFP A;  1YHL A;  1N1B A;  3LGZ B;  3P41 A;  4LXW A;  3ZCD A;  3PYA A;  3DYG A;  3VJC A;  3ZOU A;  4P0V A;  3N45 F;  4LFE A;  4LA6 A;  1HM4 A;  4EA0 A;  4OMG A;  5DW7 A;  5IKH A;  3RMG A;  3BNY A;  3CKE A;  3N3D A;  4LZ0 A;  3RBM A;  1JFA A;  3N5J F;  4L2X F;  4LZ3 A;  3WJO A;  3LZ9 A;  3G4F A;  5DGS F;  2F94 F;  3MZV A;  5EAU A;  1YYS A;  3OAB B;  3WCG A;  2F8Z F;  1N1Z A;  5JV2 F;  3TS7 A;  5H9D A;  5B0L A;  5A0J A;  4KQU A;  3S4J A;  4OKM A;  1HM7 A;  3KRF A;  3KRP A;  5ILH A;  4F6V A;  1HXG A;  5E8L A;  2AZK A;  2EWG A;  2E8V A;  1YQ7 A;  1WL2 A;  5HN7 A;  1RQJ A;  2Q9Z A;  4N1Z F;  5JV1 F;  3LEE A;  5IK6 A;  4JXY A;  5JUZ F;  2ONG A;  5ERM A;  3WEK A;  3WEF A;  4LOB A;  4GP1 A;  2I19 A;  1WMW A;  2E95 A;  5EAT A;  2PS5 A;  5CG6 A;  4MC0 A;  3TC1 A;  4NKE A;  1WY0 A;  5CG5 A;  3VJ9 A;  3Q2Q A;  5AHU B;  4KQS A;  3ADZ A;  2E91 A;  3AE0 A;  3IBA A;  1VG3 A;  4UMJ A;  3KRA A;  5DZ2 A;  1YV5 A;  3SDR A;  5JA0 F;  2E92 A;  2ONH A;  2FTZ A;  4QXS F;  2AEL A;  3M0G A;  3UCA A;  5B03 A;  3P8R A;  4P0X A;  3KRC A;  3WCC A;  2Z4W A;  3LGK A;  3NPK A;  1VG2 A;  2Z4V A;  4PVY F;  3PYB A;  1YYR A;  3VJE A;  1YHK A;  4ZQ8 A;  3ZMB A;  1WL3 A;  4NUA A;  4RXC A;  4LLS A;  4KWD A;  2PS4 A;  5IL8 A;  2H8O A;  1V4J A;  4JXN A;  5A0K A;  2F7M F;  5ILD A;  5B0K A;  4NKF A;  5IN8 A;  3ZMC A;  2PS7 A;  5B02 A;  3EZ3 A;  4NFI F;  2VF6 A;  3SDU A;  2Z52 A;  3KRO A;  4DEM F;  1VG7 A;  4QPF A;  5B00 A;  3WCE A;  2OGD A;  4N9U A;  2ZCS A;  3APZ A;  1DGP A;  4RNQ A;  4EA1 A;  2E4O A;  2ZEV A;  4JVJ F;  4NFK F;  4WK5 A;  5A0I A;  4FP4 A;  2Q9Y A;  4GP2 A;  5IL3 A;  1KIY A;  4K10 A;  2E8W A;  4E1E A;  2DH4 A;  5DIQ F;  3RYE A;  3WEI A;  5E8K A;  2Z78 A;  2ZCQ A;  3EGT A;  3WSA A;  4KVD A;  3VJB A;  4NG6 A;  5DGN F;  3CP6 A;  3WJN A;  4KKM A;  2J1P A;  2ZCO A;  3RYW A;  4KPD A;  3WCJ A;  4DI5 A;  3N3L F;  4MC3 A;  5I1U A; 
#chains in the Genus database with same CATH topology
 3DYH A;  4LPH F;  3ICM A;  1WL0 A;  4KK2 A;  5B0M A;  3SDT A;  3V1X A;  2E8T A;  2Z4Y A;  3LSN A;  2ZY1 A;  3WCA A;  2F8C F;  2O1O A;  5E8H A;  2RAH A;  4XQR F;  2E8X A;  3SAE A;  3N46 F;  3OAB A;  4RXA A;  4DHD A;  1RQI A;  5DJP F;  3LLW A;  3N0G A;  4KVY A;  3ID0 A;  1V4I A;  3P8L A;  4LZC A;  5ERN A;  4PVX F;  1N22 A;  2J5C A;  2F92 F;  4LTZ A;  4KVW A;  5C05 A;  2AEK A;  3LVS A;  4EA2 A;  2Z50 A;  3SDQ A;  3N0F A;  1UBV A;  4JZX A;  4XQS F;  3WEJ A;  3PKO A;  5DJV F;  5ILI A;  3WEG A;  2E94 A;  5ILY A;  2PS8 A;  2AZL A;  3LOM A;  4H5E F;  4H5D F;  5B01 A;  3M9U A;  3NPR A;  2ZCR A;  1UBW A;  2Q80 A;  1UBY A;  3WSB A;  5HNA A;  2J1O A;  3ACX A;  2Q58 A;  5ERO A;  5B0I A;  3LMD A;  3B7L A;  4KVI A;  1HXA A;  3WCD A;  3DYF A;  4RXE A;  3AQC B;  3TFN A;  3N5H F;  1DI1 A;  4LFG A;  1RTR A;  3M01 A;  5ER8 A;  3M00 A;  4DXJ A;  2E90 A;  2ZEU A;  3IPI A;  3Q30 A;  3VJA A;  4XQT F;  3NRI A;  4OKZ A;  3ZL6 A;  3QQV A;  4HD1 A;  3WC9 A;  5ILK A;  5IMN A;  4KPJ A;  4LUU A;  1N20 A;  1VG6 A;  2PS6 A;  5AEL A;  3AQB B;  4H5C F;  4LLT A;  3WCL A;  4F6X A;  1EZF A;  3W7F A;  3WCM A;  3OAC A;  3KRF B;  3KRP B;  1PS1 A;  3NF2 A;  4OMH A;  2Z7H A;  5DHI A;  3WJK A;  1WL1 A;  4GA3 A;  1N23 A;  4JYX A;  1YYU A;  2OA6 A;  4LTV A;  3WCF A;  1YJ4 A;  3CC9 A;  2E8U A;  1HX9 A;  3PDE A;  1KIZ A;  3MAV A;  4MC8 A;  3SDV A;  4DWB A;  5EAS A;  3LG5 A;  3PH7 A;  3V1V A;  5KSX F;  2QIS A;  5IVG A;  3VJD A;  4E9U A;  3ACY A;  3WCH A;  3KBK A;  2OPM A;  3EFQ A;  3G4D A;  4KFA A;  2OPN A;  3M02 A;  4NFJ F;  1N24 A;  3N1W F;  3ICZ A;  4Q23 A;  1V4K A;  2Z4X A;  3ICK A;  3KRA B;  4LPG F;  2AZJ A;  5IKA A;  3S9V A;  3P5P A;  3N49 F;  3Q1O A;  3LJI A;  4GAX A;  3KRC B;  4LA5 A;  1ZW5 A;  3TFV A;  5HN8 A;  5IMP A;  2FOR A;  5AFX A;  4DZW A;  1UBX A;  5DGM F;  4RXD A;  5IM1 A;  3P5R A;  1VG4 A;  1YYQ A;  5ILJ A;  5IMI A;  3BNX A;  2AET A;  3V66 A;  3ICN A;  4RYP A;  5DJR F;  3WEH A;  4DWG A;  5JV0 F;  5B0J A;  3WE9 A;  5IK0 A;  3N1V F;  4OGU A;  2F9K F;  5DHK A;  3Q2Z A;  5IK9 A;  1WKZ A;  2Z7I A;  1YYT A;  3WCB A;  4E9Z A;  4JZB A;  1HXC A;  4KQ5 A;  1V4E A;  3N6K F;  3KRO B;  1YHM A;  3OAC B;  1JFG A;  3QKC A;  4LFV F;  4LIX A;  3ACW A;  3LDW A;  2Z4Z A;  3AQ0 A;  3OYR A;  2F89 F;  5ILZ A;  4P0W A;  5AYP A;  4F62 A;  4KUX A;  4FJQ A;  1V4H A;  3WCI A;  3ASX A;  1FPS A;  2P1C A;  3LK5 A;  5HN9 A;  1N21 A;  2E93 A;  3VJ8 A;  3KB9 A;  3TFP A;  1YHL A;  1N1B A;  3LGZ B;  3P41 A;  4LXW A;  3ZCD A;  3PYA A;  3DYG A;  3VJC A;  3ZOU A;  4P0V A;  3N45 F;  4LFE A;  4LA6 A;  1HM4 A;  4EA0 A;  4OMG A;  5DW7 A;  5IKH A;  3RMG A;  3BNY A;  3CKE A;  3N3D A;  4LZ0 A;  3RBM A;  1JFA A;  3N5J F;  4L2X F;  4LZ3 A;  3WJO A;  3LZ9 A;  3G4F A;  5DGS F;  2F94 F;  3MZV A;  5EAU A;  1YYS A;  3OAB B;  3WCG A;  2F8Z F;  1N1Z A;  5JV2 F;  3TS7 A;  5H9D A;  5B0L A;  5A0J A;  4KQU A;  3S4J A;  4OKM A;  1HM7 A;  3KRF A;  3KRP A;  5ILH A;  4F6V A;  1HXG A;  5E8L A;  2AZK A;  2EWG A;  2E8V A;  1YQ7 A;  1WL2 A;  5HN7 A;  1RQJ A;  2Q9Z A;  4N1Z F;  5JV1 F;  3LEE A;  5IK6 A;  4JXY A;  5JUZ F;  2ONG A;  5ERM A;  3WEK A;  3WEF A;  4LOB A;  4GP1 A;  2I19 A;  1WMW A;  2E95 A;  5EAT A;  2PS5 A;  5CG6 A;  4MC0 A;  3TC1 A;  4NKE A;  1WY0 A;  5CG5 A;  3VJ9 A;  3Q2Q A;  5AHU B;  4KQS A;  3ADZ A;  2E91 A;  3AE0 A;  3IBA A;  1VG3 A;  4UMJ A;  3KRA A;  5DZ2 A;  1YV5 A;  3SDR A;  5JA0 F;  2E92 A;  2ONH A;  2FTZ A;  4QXS F;  2AEL A;  3M0G A;  3UCA A;  5B03 A;  3P8R A;  4P0X A;  3KRC A;  3WCC A;  2Z4W A;  3LGK A;  3NPK A;  1VG2 A;  2Z4V A;  4PVY F;  3PYB A;  1YYR A;  3VJE A;  1YHK A;  4ZQ8 A;  3ZMB A;  1WL3 A;  4NUA A;  4RXC A;  4LLS A;  4KWD A;  2PS4 A;  5IL8 A;  2H8O A;  1V4J A;  4JXN A;  5A0K A;  2F7M F;  5ILD A;  5B0K A;  4NKF A;  5IN8 A;  3ZMC A;  2PS7 A;  5B02 A;  3EZ3 A;  4NFI F;  2VF6 A;  3SDU A;  2Z52 A;  3KRO A;  4DEM F;  1VG7 A;  4QPF A;  5B00 A;  3WCE A;  2OGD A;  4N9U A;  2ZCS A;  3APZ A;  1DGP A;  4RNQ A;  4EA1 A;  2E4O A;  2ZEV A;  4JVJ F;  4NFK F;  4WK5 A;  5A0I A;  4FP4 A;  2Q9Y A;  4GP2 A;  5IL3 A;  1KIY A;  4K10 A;  2E8W A;  4E1E A;  2DH4 A;  5DIQ F;  3RYE A;  3WEI A;  5E8K A;  2Z78 A;  2ZCQ A;  3EGT A;  3WSA A;  4KVD A;  3VJB A;  4NG6 A;  5DGN F;  3CP6 A;  3WJN A;  4KKM A;  2J1P A;  2ZCO A;  3RYW A;  4KPD A;  3WCJ A;  4DI5 A;  3N3L F;  4MC3 A;  5I1U A; 
#chains in the Genus database with same CATH homology
 3DYH A;  4LPH F;  3ICM A;  1WL0 A;  4KK2 A;  5B0M A;  3SDT A;  3V1X A;  2E8T A;  2Z4Y A;  3LSN A;  2ZY1 A;  3WCA A;  2F8C F;  2O1O A;  5E8H A;  2RAH A;  4XQR F;  2E8X A;  3SAE A;  3N46 F;  3OAB A;  4RXA A;  4DHD A;  1RQI A;  5DJP F;  3LLW A;  3N0G A;  4KVY A;  3ID0 A;  1V4I A;  3P8L A;  4LZC A;  5ERN A;  4PVX F;  1N22 A;  2J5C A;  2F92 F;  4LTZ A;  4KVW A;  5C05 A;  2AEK A;  3LVS A;  4EA2 A;  2Z50 A;  3SDQ A;  3N0F A;  1UBV A;  4JZX A;  4XQS F;  3WEJ A;  3PKO A;  5DJV F;  5ILI A;  3WEG A;  2E94 A;  5ILY A;  2PS8 A;  2AZL A;  3LOM A;  4H5E F;  4H5D F;  5B01 A;  3M9U A;  3NPR A;  2ZCR A;  1UBW A;  2Q80 A;  1UBY A;  3WSB A;  5HNA A;  2J1O A;  3ACX A;  2Q58 A;  5ERO A;  5B0I A;  3LMD A;  3B7L A;  4KVI A;  1HXA A;  3WCD A;  3DYF A;  4RXE A;  3AQC B;  3TFN A;  3N5H F;  1DI1 A;  4LFG A;  1RTR A;  3M01 A;  5ER8 A;  3M00 A;  4DXJ A;  2E90 A;  2ZEU A;  3IPI A;  3Q30 A;  3VJA A;  4XQT F;  3NRI A;  4OKZ A;  3ZL6 A;  3QQV A;  4HD1 A;  3WC9 A;  5ILK A;  5IMN A;  4KPJ A;  4LUU A;  1N20 A;  1VG6 A;  2PS6 A;  5AEL A;  3AQB B;  4H5C F;  4LLT A;  3WCL A;  4F6X A;  1EZF A;  3W7F A;  3WCM A;  3OAC A;  3KRF B;  3KRP B;  1PS1 A;  3NF2 A;  4OMH A;  2Z7H A;  5DHI A;  3WJK A;  1WL1 A;  4GA3 A;  1N23 A;  4JYX A;  1YYU A;  2OA6 A;  4LTV A;  3WCF A;  1YJ4 A;  3CC9 A;  2E8U A;  1HX9 A;  3PDE A;  1KIZ A;  3MAV A;  4MC8 A;  3SDV A;  4DWB A;  5EAS A;  3LG5 A;  3PH7 A;  3V1V A;  5KSX F;  2QIS A;  5IVG A;  3VJD A;  4E9U A;  3ACY A;  3WCH A;  3KBK A;  2OPM A;  3EFQ A;  3G4D A;  4KFA A;  2OPN A;  3M02 A;  4NFJ F;  1N24 A;  3N1W F;  3ICZ A;  4Q23 A;  1V4K A;  2Z4X A;  3ICK A;  3KRA B;  4LPG F;  2AZJ A;  5IKA A;  3S9V A;  3P5P A;  3N49 F;  3Q1O A;  3LJI A;  4GAX A;  3KRC B;  4LA5 A;  1ZW5 A;  3TFV A;  5HN8 A;  5IMP A;  2FOR A;  5AFX A;  4DZW A;  1UBX A;  5DGM F;  4RXD A;  5IM1 A;  3P5R A;  1VG4 A;  1YYQ A;  5ILJ A;  5IMI A;  3BNX A;  2AET A;  3V66 A;  3ICN A;  4RYP A;  5DJR F;  3WEH A;  4DWG A;  5JV0 F;  5B0J A;  3WE9 A;  5IK0 A;  3N1V F;  4OGU A;  2F9K F;  5DHK A;  3Q2Z A;  5IK9 A;  1WKZ A;  2Z7I A;  1YYT A;  3WCB A;  4E9Z A;  4JZB A;  1HXC A;  4KQ5 A;  1V4E A;  3N6K F;  3KRO B;  1YHM A;  3OAC B;  1JFG A;  3QKC A;  4LFV F;  4LIX A;  3ACW A;  3LDW A;  2Z4Z A;  3AQ0 A;  3OYR A;  2F89 F;  5ILZ A;  4P0W A;  5AYP A;  4F62 A;  4KUX A;  4FJQ A;  1V4H A;  3WCI A;  3ASX A;  1FPS A;  2P1C A;  3LK5 A;  5HN9 A;  1N21 A;  2E93 A;  3VJ8 A;  3KB9 A;  3TFP A;  1YHL A;  1N1B A;  3LGZ B;  3P41 A;  4LXW A;  3ZCD A;  3PYA A;  3DYG A;  3VJC A;  3ZOU A;  4P0V A;  3N45 F;  4LFE A;  4LA6 A;  1HM4 A;  4EA0 A;  4OMG A;  5DW7 A;  5IKH A;  3RMG A;  3BNY A;  3CKE A;  3N3D A;  4LZ0 A;  3RBM A;  1JFA A;  3N5J F;  4L2X F;  4LZ3 A;  3WJO A;  3LZ9 A;  3G4F A;  5DGS F;  2F94 F;  3MZV A;  5EAU A;  1YYS A;  3OAB B;  3WCG A;  2F8Z F;  1N1Z A;  5JV2 F;  3TS7 A;  5H9D A;  5B0L A;  5A0J A;  4KQU A;  3S4J A;  4OKM A;  1HM7 A;  3KRF A;  3KRP A;  5ILH A;  4F6V A;  1HXG A;  5E8L A;  2AZK A;  2EWG A;  2E8V A;  1YQ7 A;  1WL2 A;  5HN7 A;  1RQJ A;  2Q9Z A;  4N1Z F;  5JV1 F;  3LEE A;  5IK6 A;  4JXY A;  5JUZ F;  2ONG A;  5ERM A;  3WEK A;  3WEF A;  4LOB A;  4GP1 A;  2I19 A;  1WMW A;  2E95 A;  5EAT A;  2PS5 A;  5CG6 A;  4MC0 A;  3TC1 A;  4NKE A;  1WY0 A;  5CG5 A;  3VJ9 A;  3Q2Q A;  5AHU B;  4KQS A;  3ADZ A;  2E91 A;  3AE0 A;  3IBA A;  1VG3 A;  4UMJ A;  3KRA A;  5DZ2 A;  1YV5 A;  3SDR A;  5JA0 F;  2E92 A;  2ONH A;  2FTZ A;  4QXS F;  2AEL A;  3M0G A;  3UCA A;  5B03 A;  3P8R A;  4P0X A;  3KRC A;  3WCC A;  2Z4W A;  3LGK A;  3NPK A;  1VG2 A;  2Z4V A;  4PVY F;  3PYB A;  1YYR A;  3VJE A;  1YHK A;  4ZQ8 A;  3ZMB A;  1WL3 A;  4NUA A;  4RXC A;  4LLS A;  4KWD A;  2PS4 A;  5IL8 A;  2H8O A;  1V4J A;  4JXN A;  5A0K A;  2F7M F;  5ILD A;  5B0K A;  4NKF A;  5IN8 A;  3ZMC A;  2PS7 A;  5B02 A;  3EZ3 A;  4NFI F;  2VF6 A;  3SDU A;  2Z52 A;  3KRO A;  4DEM F;  1VG7 A;  4QPF A;  5B00 A;  3WCE A;  2OGD A;  4N9U A;  2ZCS A;  3APZ A;  1DGP A;  4RNQ A;  4EA1 A;  2E4O A;  2ZEV A;  4JVJ F;  4NFK F;  4WK5 A;  5A0I A;  4FP4 A;  2Q9Y A;  4GP2 A;  5IL3 A;  1KIY A;  4K10 A;  2E8W A;  4E1E A;  2DH4 A;  5DIQ F;  3RYE A;  3WEI A;  5E8K A;  2Z78 A;  2ZCQ A;  3EGT A;  3WSA A;  4KVD A;  3VJB A;  4NG6 A;  5DGN F;  3CP6 A;  3WJN A;  4KKM A;  2J1P A;  2ZCO A;  3RYW A;  4KPD A;  3WCJ A;  4DI5 A;  3N3L F;  4MC3 A;  5I1U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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