4PVYF

Crystal structure of human fpps in complex with [({5-[4-(propan-2-yloxy)phenyl]pyridin-3-yl}amino)methanediyl]bis(phosphonic acid)
Total Genus 140
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
140
sequence length
346
structure length
346
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Farnesyl pyrophosphate synthase
publication title Crystallographic and thermodynamic characterization of phenylaminopyridine bisphosphonates binding to human farnesyl pyrophosphate synthase.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase/transferase inhibitor
total genus 140
structure length 346
sequence length 346
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2014-03-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4pvyF00
2E8TA 1YYQA 3LDWA 5CG5A 4LA5A 3WCMA 2QISA 5B0KA 2PS5A 3NPKA 5DZ2A 3CKEA 3WCFA 5E8LA 1KIZA 1JFAA 3ACWA 3LMDA 4OGUA 3M02A 1HM7A 2PS8A 4RXEA 4NUAA 3V66A 4GP2A 3KRFA 2Q9YA 1RTRA 1YYUA 2RAHA 1JFGA 2DH4A 4WK5A 3LVSA 3OABB 3ASXA 1N1ZA 3WCDA 5EATA 3WCGA 4LUUA 2E93A 4EA2A 5B0MA 3ADZA 4JXNA 2Z4YA 3DYHA 4GP1A 1YQ7A 5E8HA 4LLSA 1N22A 3ZMBA 3BNYA 3WJKA 5DHIA 1ZW5A 4LPGF 5ERNA 3SDRA 4LZ0A 4OMHA 3KRPB 5DIQF 3S9VA 5C05A 3ICNA 4OKMA 5AFXA 4NKEA 4LFEA 5JV2F 5ERMA 2F8CF 2I19A 3N0FA 1HM4A 1N23A 4KVDA 4KQ5A 1UBWA 3Q1OA 4QXSF 3AQBB 1WL1A 4LLTA 5B0IA 5B02A 5ILDA 3WSAA 4JZXA 3WCHA 5DJRF 3ID0A 2E8VA 3V1VA 5IK9A 3WCEA 5IVGA 4HD1A 5ILJA 2OPMA 4ZQ8A 4QPFA 1VG4A 3N46F 4NFJF 4XQSF 2Z4XA 3EZ3A 3LK5A 5DJVF 3WEFA 2PS7A 3LOMA 2AELA 2AZJA 1WY0A 5DGMF 3AQ0A 3WCAA 1KIYA 2E90A 3TFNA 1DGPA 4KUXA 4P0VA 2ZEUA 4F6XA 4RYPA 2Z7IA 2E8WA 3WEJA 2J1OA 2EWGA 3WCBA 1V4HA 2J1PA 1YJ4A 4MC0A 1HXAA 4DHDA 2AEKA 4H5EF 3N45F 4RXAA 3CC9A 3N1WF 1UBYA 2F9KF 5ILIA 5EAUA 1V4KA 4DEMF 2J5CA 3KRPA 4E9ZA 4LA6A 1RQJA 4F62A 5EASA 4RXCA 1UBXA 4DI5A 3AE0A 1HXCA 2E92A 3NPRA 3TFVA 2VF6A 5ER8A 1N1BA 2ZY1A 3M01A 3LZ9A 4RXDA 1VG7A 3PDEA 4KWDA 3RYWA 5B03A 2Z4WA 3QQVA 1YYRA 3PH7A 3ZOUA 3WCJA 4LTZA 1N20A 5IL3A 4P0XA 1N21A 5AHUB 3APZA 2Z7HA 3KRAB 2E8UA 4NG6A 5IN8A 1V4IA 3IPIA 4N9UA 4EA0A 5HN7A 2F94F 3LG5A 1DI1A 1YYSA 2OGDA 3ICKA 4DZWA 4H5DF 2ONHA 3KRCB 4E9UA 3P8LA 2F89F 3DYGA 3ACYA 3P41A 4KQSA 2Q9ZA 4JXYA 5ILYA 3LGZB 4NFIF 3S4JA 1HX9A 3V1XA 4EA1A 3RBMA 4PVYF 4P0WA 3M00A 4LZ3A 3LGKA 4DWGA 4GAXA 4H5CF 3G4FA 4KFAA 5A0JA 3Q2ZA 3LSNA 1WL3A 3WE9A 4GA3A 5B01A 2PS4A 2E95A 3KROB 4JZBA 4MC3A 3P5PA 2Z4VA 5IKAA 2E4OA 4PVXF 3M9UA 2PS6A 4UMJA 3VJCA 4NKFA 5JUZF 3RYEA 3SDTA 3EFQA 2E91A 3SDVA 5DGSF 5IMNA 1V4EA 4KVWA 5IKHA 4LOBA 3VJ8A 3OABA 5CG6A 3WJOA 1VG3A 5B0LA 2P1CA 5IMIA 3WC9A 3BNXA 4LTVA 3PKOA 4LXWA 3MZVA 3SDUA 5IM1A 2Z50A 3VJ9A 4LFVF 4KQUA 5DGNF 3EGTA 3N5HF 3DYFA 4KVIA 3WJNA 1PS1A 3KRAA 3Q30A 4KVYA 3WCCA 4K10A 3N1VF 2FTZA 1YYTA 5B0JA 5ILKA 5E8KA 4F6VA 4L2XF 2AZLA 5DHKA 3PYAA 3TS7A 4RNQA 1EZFA 4FJQA 4KK2A 4DWBA 5AYPA 3W7FA 3KBKA 3WEHA 5HN9A 1HXGA 5HN8A 3N5JF 1VG2A 5IK0A 2ZCRA 3LLWA 5JA0F 2ZEVA 5JV0F 4LIXA 2ZCQA 4NFKF 5AELA 4JVJF 3NF2A 3N0GA 1WL0A 2OPNA 3SDQA 4LFGA 3ICMA 4XQRF 1YHMA 4OMGA 3P8RA 2E94A 3WCLA 3KROA 3IBAA 3KB9A 3VJAA 3B7LA 5A0IA 2F8ZF 3N3LF 3ZMCA 3P5RA 3LJIA 4E1EA 2ONGA 2ZCSA 5ILHA 5KSXF 5I1UA 1WMWA 5DW7A 1WL2A 1YV5A 5B00A 3N3DA 3UCAA 3OACB 4KKMA 3OYRA 3WEGA 3WEIA 2F92F 4Q23A 5JV1F 3WSBA 3N6KF 4FP4A 2AETA 5DJPF 1VG6A 2Z78A 3CP6A 3NRIA 2O1OA 3AQCB 3RMGA 4MC8A 3KRFB 1UBVA 4N1ZF 3M0GA 5H9DA 3G4DA 2Z4ZA 3SAEA 1YHLA 2FORA 5IL8A 4JYXA 3ICZA 1YHKA 3ACXA 3VJBA 2H8OA 4LZCA 2AZKA 1WKZA 4KPDA 3WEKA 2F7MF 2OA6A 1V4JA 3PYBA 1RQIA 4KPJA 3TC1A 2Z52A 5IK6A 3VJEA 3N49F 3MAVA 3VJDA 3WCIA 3LEEA 2Q58A 4LPHF 3Q2QA 5A0KA 1FPSA 3TFPA 3QKCA 3KRCA 1N24A 4OKZA 3ZCDA 2ZCOA 5ILZA 5EROA 5HNAA 3ZL6A 4DXJA 5IMPA 3OACA 2Q80A 2E8XA 4XQTF
chains in the Genus database with same CATH superfamily
2E8TA 1YYQA 3LDWA 5CG5A 4LA5A 3WCMA 2QISA 5B0KA 2PS5A 3NPKA 5DZ2A 3CKEA 3WCFA 5E8LA 1KIZA 1JFAA 3ACWA 3LMDA 4OGUA 3M02A 1HM7A 2PS8A 4RXEA 4NUAA 3V66A 4GP2A 3KRFA 2Q9YA 1RTRA 1YYUA 2RAHA 1JFGA 2DH4A 4WK5A 3LVSA 3OABB 3ASXA 1N1ZA 3WCDA 5EATA 3WCGA 4LUUA 2E93A 4EA2A 5B0MA 3ADZA 4JXNA 2Z4YA 3DYHA 4GP1A 1YQ7A 5E8HA 4LLSA 1N22A 3ZMBA 3BNYA 3WJKA 5DHIA 1ZW5A 4LPGF 5ERNA 3SDRA 4LZ0A 4OMHA 3KRPB 5DIQF 3S9VA 5C05A 3ICNA 4OKMA 5AFXA 4NKEA 4LFEA 5JV2F 5ERMA 2F8CF 2I19A 3N0FA 1HM4A 1N23A 4KVDA 4KQ5A 1UBWA 3Q1OA 4QXSF 3AQBB 1WL1A 4LLTA 5B0IA 5B02A 5ILDA 3WSAA 4JZXA 3WCHA 5DJRF 3ID0A 2E8VA 3V1VA 5IK9A 3WCEA 5IVGA 4HD1A 5ILJA 2OPMA 4ZQ8A 4QPFA 1VG4A 3N46F 4NFJF 4XQSF 2Z4XA 3EZ3A 3LK5A 5DJVF 3WEFA 2PS7A 3LOMA 2AELA 2AZJA 1WY0A 5DGMF 3AQ0A 3WCAA 1KIYA 2E90A 3TFNA 1DGPA 4KUXA 4P0VA 2ZEUA 4F6XA 4RYPA 2Z7IA 2E8WA 3WEJA 2J1OA 2EWGA 3WCBA 1V4HA 2J1PA 1YJ4A 4MC0A 1HXAA 4DHDA 2AEKA 4H5EF 3N45F 4RXAA 3CC9A 3N1WF 1UBYA 2F9KF 5ILIA 5EAUA 1V4KA 4DEMF 2J5CA 3KRPA 4E9ZA 4LA6A 1RQJA 4F62A 5EASA 4RXCA 1UBXA 4DI5A 3AE0A 1HXCA 2E92A 3NPRA 3TFVA 2VF6A 5ER8A 1N1BA 2ZY1A 3M01A 3LZ9A 4RXDA 1VG7A 3PDEA 4KWDA 3RYWA 5B03A 2Z4WA 3QQVA 1YYRA 3PH7A 3ZOUA 3WCJA 4LTZA 1N20A 5IL3A 4P0XA 1N21A 5AHUB 3APZA 2Z7HA 3KRAB 2E8UA 4NG6A 5IN8A 1V4IA 3IPIA 4N9UA 4EA0A 5HN7A 2F94F 3LG5A 1DI1A 1YYSA 2OGDA 3ICKA 4DZWA 4H5DF 2ONHA 3KRCB 4E9UA 3P8LA 2F89F 3DYGA 3ACYA 3P41A 4KQSA 2Q9ZA 4JXYA 5ILYA 3LGZB 4NFIF 3S4JA 1HX9A 3V1XA 4EA1A 3RBMA 4PVYF 4P0WA 3M00A 4LZ3A 3LGKA 4DWGA 4GAXA 4H5CF 3G4FA 4KFAA 5A0JA 3Q2ZA 3LSNA 1WL3A 3WE9A 4GA3A 5B01A 2PS4A 2E95A 3KROB 4JZBA 4MC3A 3P5PA 2Z4VA 5IKAA 2E4OA 4PVXF 3M9UA 2PS6A 4UMJA 3VJCA 4NKFA 5JUZF 3RYEA 3SDTA 3EFQA 2E91A 3SDVA 5DGSF 5IMNA 1V4EA 4KVWA 5IKHA 4LOBA 3VJ8A 3OABA 5CG6A 3WJOA 1VG3A 5B0LA 2P1CA 5IMIA 3WC9A 3BNXA 4LTVA 3PKOA 4LXWA 3MZVA 3SDUA 5IM1A 2Z50A 3VJ9A 4LFVF 4KQUA 5DGNF 3EGTA 3N5HF 3DYFA 4KVIA 3WJNA 1PS1A 3KRAA 3Q30A 4KVYA 3WCCA 4K10A 3N1VF 2FTZA 1YYTA 5B0JA 5ILKA 5E8KA 4F6VA 4L2XF 2AZLA 5DHKA 3PYAA 3TS7A 4RNQA 1EZFA 4FJQA 4KK2A 4DWBA 5AYPA 3W7FA 3KBKA 3WEHA 5HN9A 1HXGA 5HN8A 3N5JF 1VG2A 5IK0A 2ZCRA 3LLWA 5JA0F 2ZEVA 5JV0F 4LIXA 2ZCQA 4NFKF 5AELA 4JVJF 3NF2A 3N0GA 1WL0A 2OPNA 3SDQA 4LFGA 3ICMA 4XQRF 1YHMA 4OMGA 3P8RA 2E94A 3WCLA 3KROA 3IBAA 3KB9A 3VJAA 3B7LA 5A0IA 2F8ZF 3N3LF 3ZMCA 3P5RA 3LJIA 4E1EA 2ONGA 2ZCSA 5ILHA 5KSXF 5I1UA 1WMWA 5DW7A 1WL2A 1YV5A 5B00A 3N3DA 3UCAA 3OACB 4KKMA 3OYRA 3WEGA 3WEIA 2F92F 4Q23A 5JV1F 3WSBA 3N6KF 4FP4A 2AETA 5DJPF 1VG6A 2Z78A 3CP6A 3NRIA 2O1OA 3AQCB 3RMGA 4MC8A 3KRFB 1UBVA 4N1ZF 3M0GA 5H9DA 3G4DA 2Z4ZA 3SAEA 1YHLA 2FORA 5IL8A 4JYXA 3ICZA 1YHKA 3ACXA 3VJBA 2H8OA 4LZCA 2AZKA 1WKZA 4KPDA 3WEKA 2F7MF 2OA6A 1V4JA 3PYBA 1RQIA 4KPJA 3TC1A 2Z52A 5IK6A 3VJEA 3N49F 3MAVA 3VJDA 3WCIA 3LEEA 2Q58A 4LPHF 3Q2QA 5A0KA 1FPSA 3TFPA 3QKCA 3KRCA 1N24A 4OKZA 3ZCDA 2ZCOA 5ILZA 5EROA 5HNAA 3ZL6A 4DXJA 5IMPA 3OACA 2Q80A 2E8XA 4XQTF
chains in the Genus database with same CATH topology
2E8TA 1YYQA 3LDWA 5CG5A 4LA5A 3WCMA 2QISA 5B0KA 2PS5A 3NPKA 5DZ2A 3CKEA 3WCFA 5E8LA 1KIZA 1JFAA 3ACWA 3LMDA 4OGUA 3M02A 1HM7A 2PS8A 4RXEA 4NUAA 3V66A 4GP2A 3KRFA 2Q9YA 1RTRA 1YYUA 2RAHA 1JFGA 2DH4A 4WK5A 3LVSA 3OABB 3ASXA 1N1ZA 3WCDA 5EATA 3WCGA 4LUUA 2E93A 4EA2A 5B0MA 3ADZA 4JXNA 2Z4YA 3DYHA 4GP1A 1YQ7A 5E8HA 4LLSA 1N22A 3ZMBA 3BNYA 3WJKA 5DHIA 1ZW5A 4LPGF 5ERNA 3SDRA 4LZ0A 4OMHA 3KRPB 5DIQF 3S9VA 5C05A 3ICNA 4OKMA 5AFXA 4NKEA 4LFEA 5JV2F 5ERMA 2F8CF 2I19A 3N0FA 1HM4A 1N23A 4KVDA 4KQ5A 1UBWA 3Q1OA 4QXSF 3AQBB 1WL1A 4LLTA 5B0IA 5B02A 5ILDA 3WSAA 4JZXA 3WCHA 5DJRF 3ID0A 2E8VA 3V1VA 5IK9A 3WCEA 5IVGA 4HD1A 5ILJA 2OPMA 4ZQ8A 4QPFA 1VG4A 3N46F 4NFJF 4XQSF 2Z4XA 3EZ3A 3LK5A 5DJVF 3WEFA 2PS7A 3LOMA 2AELA 2AZJA 1WY0A 5DGMF 3AQ0A 3WCAA 1KIYA 2E90A 3TFNA 1DGPA 4KUXA 4P0VA 2ZEUA 4F6XA 4RYPA 2Z7IA 2E8WA 3WEJA 2J1OA 2EWGA 3WCBA 1V4HA 2J1PA 1YJ4A 4MC0A 1HXAA 4DHDA 2AEKA 4H5EF 3N45F 4RXAA 3CC9A 3N1WF 1UBYA 2F9KF 5ILIA 5EAUA 1V4KA 4DEMF 2J5CA 3KRPA 4E9ZA 4LA6A 1RQJA 4F62A 5EASA 4RXCA 1UBXA 4DI5A 3AE0A 1HXCA 2E92A 3NPRA 3TFVA 2VF6A 5ER8A 1N1BA 2ZY1A 3M01A 3LZ9A 4RXDA 1VG7A 3PDEA 4KWDA 3RYWA 5B03A 2Z4WA 3QQVA 1YYRA 3PH7A 3ZOUA 3WCJA 4LTZA 1N20A 5IL3A 4P0XA 1N21A 5AHUB 3APZA 2Z7HA 3KRAB 2E8UA 4NG6A 5IN8A 1V4IA 3IPIA 4N9UA 4EA0A 5HN7A 2F94F 3LG5A 1DI1A 1YYSA 2OGDA 3ICKA 4DZWA 4H5DF 2ONHA 3KRCB 4E9UA 3P8LA 2F89F 3DYGA 3ACYA 3P41A 4KQSA 2Q9ZA 4JXYA 5ILYA 3LGZB 4NFIF 3S4JA 1HX9A 3V1XA 4EA1A 3RBMA 4PVYF 4P0WA 3M00A 4LZ3A 3LGKA 4DWGA 4GAXA 4H5CF 3G4FA 4KFAA 5A0JA 3Q2ZA 3LSNA 1WL3A 3WE9A 4GA3A 5B01A 2PS4A 2E95A 3KROB 4JZBA 4MC3A 3P5PA 2Z4VA 5IKAA 2E4OA 4PVXF 3M9UA 2PS6A 4UMJA 3VJCA 4NKFA 5JUZF 3RYEA 3SDTA 3EFQA 2E91A 3SDVA 5DGSF 5IMNA 1V4EA 4KVWA 5IKHA 4LOBA 3VJ8A 3OABA 5CG6A 3WJOA 1VG3A 5B0LA 2P1CA 5IMIA 3WC9A 3BNXA 4LTVA 3PKOA 4LXWA 3MZVA 3SDUA 5IM1A 2Z50A 3VJ9A 4LFVF 4KQUA 5DGNF 3EGTA 3N5HF 3DYFA 4KVIA 3WJNA 1PS1A 3KRAA 3Q30A 4KVYA 3WCCA 4K10A 3N1VF 2FTZA 1YYTA 5B0JA 5ILKA 5E8KA 4F6VA 4L2XF 2AZLA 5DHKA 3PYAA 3TS7A 4RNQA 1EZFA 4FJQA 4KK2A 4DWBA 5AYPA 3W7FA 3KBKA 3WEHA 5HN9A 1HXGA 5HN8A 3N5JF 1VG2A 5IK0A 2ZCRA 3LLWA 5JA0F 2ZEVA 5JV0F 4LIXA 2ZCQA 4NFKF 5AELA 4JVJF 3NF2A 3N0GA 1WL0A 2OPNA 3SDQA 4LFGA 3ICMA 4XQRF 1YHMA 4OMGA 3P8RA 2E94A 3WCLA 3KROA 3IBAA 3KB9A 3VJAA 3B7LA 5A0IA 2F8ZF 3N3LF 3ZMCA 3P5RA 3LJIA 4E1EA 2ONGA 2ZCSA 5ILHA 5KSXF 5I1UA 1WMWA 5DW7A 1WL2A 1YV5A 5B00A 3N3DA 3UCAA 3OACB 4KKMA 3OYRA 3WEGA 3WEIA 2F92F 4Q23A 5JV1F 3WSBA 3N6KF 4FP4A 2AETA 5DJPF 1VG6A 2Z78A 3CP6A 3NRIA 2O1OA 3AQCB 3RMGA 4MC8A 3KRFB 1UBVA 4N1ZF 3M0GA 5H9DA 3G4DA 2Z4ZA 3SAEA 1YHLA 2FORA 5IL8A 4JYXA 3ICZA 1YHKA 3ACXA 3VJBA 2H8OA 4LZCA 2AZKA 1WKZA 4KPDA 3WEKA 2F7MF 2OA6A 1V4JA 3PYBA 1RQIA 4KPJA 3TC1A 2Z52A 5IK6A 3VJEA 3N49F 3MAVA 3VJDA 3WCIA 3LEEA 2Q58A 4LPHF 3Q2QA 5A0KA 1FPSA 3TFPA 3QKCA 3KRCA 1N24A 4OKZA 3ZCDA 2ZCOA 5ILZA 5EROA 5HNAA 3ZL6A 4DXJA 5IMPA 3OACA 2Q80A 2E8XA 4XQTF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2E8T A;  1YYQ A;  3LDW A;  5CG5 A;  4LA5 A;  3WCM A;  2QIS A;  5B0K A;  2PS5 A;  3NPK A;  5DZ2 A;  3CKE A;  3WCF A;  5E8L A;  1KIZ A;  1JFA A;  3ACW A;  3LMD A;  4OGU A;  3M02 A;  1HM7 A;  2PS8 A;  4RXE A;  4NUA A;  3V66 A;  4GP2 A;  3KRF A;  2Q9Y A;  1RTR A;  1YYU A;  2RAH A;  1JFG A;  2DH4 A;  4WK5 A;  3LVS A;  3OAB B;  3ASX A;  1N1Z A;  3WCD A;  5EAT A;  3WCG A;  4LUU A;  2E93 A;  4EA2 A;  5B0M A;  3ADZ A;  4JXN A;  2Z4Y A;  3DYH A;  4GP1 A;  1YQ7 A;  5E8H A;  4LLS A;  1N22 A;  3ZMB A;  3BNY A;  3WJK A;  5DHI A;  1ZW5 A;  4LPG F;  5ERN A;  3SDR A;  4LZ0 A;  4OMH A;  3KRP B;  5DIQ F;  3S9V A;  5C05 A;  3ICN A;  4OKM A;  5AFX A;  4NKE A;  4LFE A;  5JV2 F;  5ERM A;  2F8C F;  2I19 A;  3N0F A;  1HM4 A;  1N23 A;  4KVD A;  4KQ5 A;  1UBW A;  3Q1O A;  4QXS F;  3AQB B;  1WL1 A;  4LLT A;  5B0I A;  5B02 A;  5ILD A;  3WSA A;  4JZX A;  3WCH A;  5DJR F;  3ID0 A;  2E8V A;  3V1V A;  5IK9 A;  3WCE A;  5IVG A;  4HD1 A;  5ILJ A;  2OPM A;  4ZQ8 A;  4QPF A;  1VG4 A;  3N46 F;  4NFJ F;  4XQS F;  2Z4X A;  3EZ3 A;  3LK5 A;  5DJV F;  3WEF A;  2PS7 A;  3LOM A;  2AEL A;  2AZJ A;  1WY0 A;  5DGM F;  3AQ0 A;  3WCA A;  1KIY A;  2E90 A;  3TFN A;  1DGP A;  4KUX A;  4P0V A;  2ZEU A;  4F6X A;  4RYP A;  2Z7I A;  2E8W A;  3WEJ A;  2J1O A;  2EWG A;  3WCB A;  1V4H A;  2J1P A;  1YJ4 A;  4MC0 A;  1HXA A;  4DHD A;  2AEK A;  4H5E F;  3N45 F;  4RXA A;  3CC9 A;  3N1W F;  1UBY A;  2F9K F;  5ILI A;  5EAU A;  1V4K A;  4DEM F;  2J5C A;  3KRP A;  4E9Z A;  4LA6 A;  1RQJ A;  4F62 A;  5EAS A;  4RXC A;  1UBX A;  4DI5 A;  3AE0 A;  1HXC A;  2E92 A;  3NPR A;  3TFV A;  2VF6 A;  5ER8 A;  1N1B A;  2ZY1 A;  3M01 A;  3LZ9 A;  4RXD A;  1VG7 A;  3PDE A;  4KWD A;  3RYW A;  5B03 A;  2Z4W A;  3QQV A;  1YYR A;  3PH7 A;  3ZOU A;  3WCJ A;  4LTZ A;  1N20 A;  5IL3 A;  4P0X A;  1N21 A;  5AHU B;  3APZ A;  2Z7H A;  3KRA B;  2E8U A;  4NG6 A;  5IN8 A;  1V4I A;  3IPI A;  4N9U A;  4EA0 A;  5HN7 A;  2F94 F;  3LG5 A;  1DI1 A;  1YYS A;  2OGD A;  3ICK A;  4DZW A;  4H5D F;  2ONH A;  3KRC B;  4E9U A;  3P8L A;  2F89 F;  3DYG A;  3ACY A;  3P41 A;  4KQS A;  2Q9Z A;  4JXY A;  5ILY A;  3LGZ B;  4NFI F;  3S4J A;  1HX9 A;  3V1X A;  4EA1 A;  3RBM A;  4PVY F;  4P0W A;  3M00 A;  4LZ3 A;  3LGK A;  4DWG A;  4GAX A;  4H5C F;  3G4F A;  4KFA A;  5A0J A;  3Q2Z A;  3LSN A;  1WL3 A;  3WE9 A;  4GA3 A;  5B01 A;  2PS4 A;  2E95 A;  3KRO B;  4JZB A;  4MC3 A;  3P5P A;  2Z4V A;  5IKA A;  2E4O A;  4PVX F;  3M9U A;  2PS6 A;  4UMJ A;  3VJC A;  4NKF A;  5JUZ F;  3RYE A;  3SDT A;  3EFQ A;  2E91 A;  3SDV A;  5DGS F;  5IMN A;  1V4E A;  4KVW A;  5IKH A;  4LOB A;  3VJ8 A;  3OAB A;  5CG6 A;  3WJO A;  1VG3 A;  5B0L A;  2P1C A;  5IMI A;  3WC9 A;  3BNX A;  4LTV A;  3PKO A;  4LXW A;  3MZV A;  3SDU A;  5IM1 A;  2Z50 A;  3VJ9 A;  4LFV F;  4KQU A;  5DGN F;  3EGT A;  3N5H F;  3DYF A;  4KVI A;  3WJN A;  1PS1 A;  3KRA A;  3Q30 A;  4KVY A;  3WCC A;  4K10 A;  3N1V F;  2FTZ A;  1YYT A;  5B0J A;  5ILK A;  5E8K A;  4F6V A;  4L2X F;  2AZL A;  5DHK A;  3PYA A;  3TS7 A;  4RNQ A;  1EZF A;  4FJQ A;  4KK2 A;  4DWB A;  5AYP A;  3W7F A;  3KBK A;  3WEH A;  5HN9 A;  1HXG A;  5HN8 A;  3N5J F;  1VG2 A;  5IK0 A;  2ZCR A;  3LLW A;  5JA0 F;  2ZEV A;  5JV0 F;  4LIX A;  2ZCQ A;  4NFK F;  5AEL A;  4JVJ F;  3NF2 A;  3N0G A;  1WL0 A;  2OPN A;  3SDQ A;  4LFG A;  3ICM A;  4XQR F;  1YHM A;  4OMG A;  3P8R A;  2E94 A;  3WCL A;  3KRO A;  3IBA A;  3KB9 A;  3VJA A;  3B7L A;  5A0I A;  2F8Z F;  3N3L F;  3ZMC A;  3P5R A;  3LJI A;  4E1E A;  2ONG A;  2ZCS A;  5ILH A;  5KSX F;  5I1U A;  1WMW A;  5DW7 A;  1WL2 A;  1YV5 A;  5B00 A;  3N3D A;  3UCA A;  3OAC B;  4KKM A;  3OYR A;  3WEG A;  3WEI A;  2F92 F;  4Q23 A;  5JV1 F;  3WSB A;  3N6K F;  4FP4 A;  2AET A;  5DJP F;  1VG6 A;  2Z78 A;  3CP6 A;  3NRI A;  2O1O A;  3AQC B;  3RMG A;  4MC8 A;  3KRF B;  1UBV A;  4N1Z F;  3M0G A;  5H9D A;  3G4D A;  2Z4Z A;  3SAE A;  1YHL A;  2FOR A;  5IL8 A;  4JYX A;  3ICZ A;  1YHK A;  3ACX A;  3VJB A;  2H8O A;  4LZC A;  2AZK A;  1WKZ A;  4KPD A;  3WEK A;  2F7M F;  2OA6 A;  1V4J A;  3PYB A;  1RQI A;  4KPJ A;  3TC1 A;  2Z52 A;  5IK6 A;  3VJE A;  3N49 F;  3MAV A;  3VJD A;  3WCI A;  3LEE A;  2Q58 A;  4LPH F;  3Q2Q A;  5A0K A;  1FPS A;  3TFP A;  3QKC A;  3KRC A;  1N24 A;  4OKZ A;  3ZCD A;  2ZCO A;  5ILZ A;  5ERO A;  5HNA A;  3ZL6 A;  4DXJ A;  5IMP A;  3OAC A;  2Q80 A;  2E8X A;  4XQT F; 
#chains in the Genus database with same CATH topology
 2E8T A;  1YYQ A;  3LDW A;  5CG5 A;  4LA5 A;  3WCM A;  2QIS A;  5B0K A;  2PS5 A;  3NPK A;  5DZ2 A;  3CKE A;  3WCF A;  5E8L A;  1KIZ A;  1JFA A;  3ACW A;  3LMD A;  4OGU A;  3M02 A;  1HM7 A;  2PS8 A;  4RXE A;  4NUA A;  3V66 A;  4GP2 A;  3KRF A;  2Q9Y A;  1RTR A;  1YYU A;  2RAH A;  1JFG A;  2DH4 A;  4WK5 A;  3LVS A;  3OAB B;  3ASX A;  1N1Z A;  3WCD A;  5EAT A;  3WCG A;  4LUU A;  2E93 A;  4EA2 A;  5B0M A;  3ADZ A;  4JXN A;  2Z4Y A;  3DYH A;  4GP1 A;  1YQ7 A;  5E8H A;  4LLS A;  1N22 A;  3ZMB A;  3BNY A;  3WJK A;  5DHI A;  1ZW5 A;  4LPG F;  5ERN A;  3SDR A;  4LZ0 A;  4OMH A;  3KRP B;  5DIQ F;  3S9V A;  5C05 A;  3ICN A;  4OKM A;  5AFX A;  4NKE A;  4LFE A;  5JV2 F;  5ERM A;  2F8C F;  2I19 A;  3N0F A;  1HM4 A;  1N23 A;  4KVD A;  4KQ5 A;  1UBW A;  3Q1O A;  4QXS F;  3AQB B;  1WL1 A;  4LLT A;  5B0I A;  5B02 A;  5ILD A;  3WSA A;  4JZX A;  3WCH A;  5DJR F;  3ID0 A;  2E8V A;  3V1V A;  5IK9 A;  3WCE A;  5IVG A;  4HD1 A;  5ILJ A;  2OPM A;  4ZQ8 A;  4QPF A;  1VG4 A;  3N46 F;  4NFJ F;  4XQS F;  2Z4X A;  3EZ3 A;  3LK5 A;  5DJV F;  3WEF A;  2PS7 A;  3LOM A;  2AEL A;  2AZJ A;  1WY0 A;  5DGM F;  3AQ0 A;  3WCA A;  1KIY A;  2E90 A;  3TFN A;  1DGP A;  4KUX A;  4P0V A;  2ZEU A;  4F6X A;  4RYP A;  2Z7I A;  2E8W A;  3WEJ A;  2J1O A;  2EWG A;  3WCB A;  1V4H A;  2J1P A;  1YJ4 A;  4MC0 A;  1HXA A;  4DHD A;  2AEK A;  4H5E F;  3N45 F;  4RXA A;  3CC9 A;  3N1W F;  1UBY A;  2F9K F;  5ILI A;  5EAU A;  1V4K A;  4DEM F;  2J5C A;  3KRP A;  4E9Z A;  4LA6 A;  1RQJ A;  4F62 A;  5EAS A;  4RXC A;  1UBX A;  4DI5 A;  3AE0 A;  1HXC A;  2E92 A;  3NPR A;  3TFV A;  2VF6 A;  5ER8 A;  1N1B A;  2ZY1 A;  3M01 A;  3LZ9 A;  4RXD A;  1VG7 A;  3PDE A;  4KWD A;  3RYW A;  5B03 A;  2Z4W A;  3QQV A;  1YYR A;  3PH7 A;  3ZOU A;  3WCJ A;  4LTZ A;  1N20 A;  5IL3 A;  4P0X A;  1N21 A;  5AHU B;  3APZ A;  2Z7H A;  3KRA B;  2E8U A;  4NG6 A;  5IN8 A;  1V4I A;  3IPI A;  4N9U A;  4EA0 A;  5HN7 A;  2F94 F;  3LG5 A;  1DI1 A;  1YYS A;  2OGD A;  3ICK A;  4DZW A;  4H5D F;  2ONH A;  3KRC B;  4E9U A;  3P8L A;  2F89 F;  3DYG A;  3ACY A;  3P41 A;  4KQS A;  2Q9Z A;  4JXY A;  5ILY A;  3LGZ B;  4NFI F;  3S4J A;  1HX9 A;  3V1X A;  4EA1 A;  3RBM A;  4PVY F;  4P0W A;  3M00 A;  4LZ3 A;  3LGK A;  4DWG A;  4GAX A;  4H5C F;  3G4F A;  4KFA A;  5A0J A;  3Q2Z A;  3LSN A;  1WL3 A;  3WE9 A;  4GA3 A;  5B01 A;  2PS4 A;  2E95 A;  3KRO B;  4JZB A;  4MC3 A;  3P5P A;  2Z4V A;  5IKA A;  2E4O A;  4PVX F;  3M9U A;  2PS6 A;  4UMJ A;  3VJC A;  4NKF A;  5JUZ F;  3RYE A;  3SDT A;  3EFQ A;  2E91 A;  3SDV A;  5DGS F;  5IMN A;  1V4E A;  4KVW A;  5IKH A;  4LOB A;  3VJ8 A;  3OAB A;  5CG6 A;  3WJO A;  1VG3 A;  5B0L A;  2P1C A;  5IMI A;  3WC9 A;  3BNX A;  4LTV A;  3PKO A;  4LXW A;  3MZV A;  3SDU A;  5IM1 A;  2Z50 A;  3VJ9 A;  4LFV F;  4KQU A;  5DGN F;  3EGT A;  3N5H F;  3DYF A;  4KVI A;  3WJN A;  1PS1 A;  3KRA A;  3Q30 A;  4KVY A;  3WCC A;  4K10 A;  3N1V F;  2FTZ A;  1YYT A;  5B0J A;  5ILK A;  5E8K A;  4F6V A;  4L2X F;  2AZL A;  5DHK A;  3PYA A;  3TS7 A;  4RNQ A;  1EZF A;  4FJQ A;  4KK2 A;  4DWB A;  5AYP A;  3W7F A;  3KBK A;  3WEH A;  5HN9 A;  1HXG A;  5HN8 A;  3N5J F;  1VG2 A;  5IK0 A;  2ZCR A;  3LLW A;  5JA0 F;  2ZEV A;  5JV0 F;  4LIX A;  2ZCQ A;  4NFK F;  5AEL A;  4JVJ F;  3NF2 A;  3N0G A;  1WL0 A;  2OPN A;  3SDQ A;  4LFG A;  3ICM A;  4XQR F;  1YHM A;  4OMG A;  3P8R A;  2E94 A;  3WCL A;  3KRO A;  3IBA A;  3KB9 A;  3VJA A;  3B7L A;  5A0I A;  2F8Z F;  3N3L F;  3ZMC A;  3P5R A;  3LJI A;  4E1E A;  2ONG A;  2ZCS A;  5ILH A;  5KSX F;  5I1U A;  1WMW A;  5DW7 A;  1WL2 A;  1YV5 A;  5B00 A;  3N3D A;  3UCA A;  3OAC B;  4KKM A;  3OYR A;  3WEG A;  3WEI A;  2F92 F;  4Q23 A;  5JV1 F;  3WSB A;  3N6K F;  4FP4 A;  2AET A;  5DJP F;  1VG6 A;  2Z78 A;  3CP6 A;  3NRI A;  2O1O A;  3AQC B;  3RMG A;  4MC8 A;  3KRF B;  1UBV A;  4N1Z F;  3M0G A;  5H9D A;  3G4D A;  2Z4Z A;  3SAE A;  1YHL A;  2FOR A;  5IL8 A;  4JYX A;  3ICZ A;  1YHK A;  3ACX A;  3VJB A;  2H8O A;  4LZC A;  2AZK A;  1WKZ A;  4KPD A;  3WEK A;  2F7M F;  2OA6 A;  1V4J A;  3PYB A;  1RQI A;  4KPJ A;  3TC1 A;  2Z52 A;  5IK6 A;  3VJE A;  3N49 F;  3MAV A;  3VJD A;  3WCI A;  3LEE A;  2Q58 A;  4LPH F;  3Q2Q A;  5A0K A;  1FPS A;  3TFP A;  3QKC A;  3KRC A;  1N24 A;  4OKZ A;  3ZCD A;  2ZCO A;  5ILZ A;  5ERO A;  5HNA A;  3ZL6 A;  4DXJ A;  5IMP A;  3OAC A;  2Q80 A;  2E8X A;  4XQT F; 
#chains in the Genus database with same CATH homology
 2E8T A;  1YYQ A;  3LDW A;  5CG5 A;  4LA5 A;  3WCM A;  2QIS A;  5B0K A;  2PS5 A;  3NPK A;  5DZ2 A;  3CKE A;  3WCF A;  5E8L A;  1KIZ A;  1JFA A;  3ACW A;  3LMD A;  4OGU A;  3M02 A;  1HM7 A;  2PS8 A;  4RXE A;  4NUA A;  3V66 A;  4GP2 A;  3KRF A;  2Q9Y A;  1RTR A;  1YYU A;  2RAH A;  1JFG A;  2DH4 A;  4WK5 A;  3LVS A;  3OAB B;  3ASX A;  1N1Z A;  3WCD A;  5EAT A;  3WCG A;  4LUU A;  2E93 A;  4EA2 A;  5B0M A;  3ADZ A;  4JXN A;  2Z4Y A;  3DYH A;  4GP1 A;  1YQ7 A;  5E8H A;  4LLS A;  1N22 A;  3ZMB A;  3BNY A;  3WJK A;  5DHI A;  1ZW5 A;  4LPG F;  5ERN A;  3SDR A;  4LZ0 A;  4OMH A;  3KRP B;  5DIQ F;  3S9V A;  5C05 A;  3ICN A;  4OKM A;  5AFX A;  4NKE A;  4LFE A;  5JV2 F;  5ERM A;  2F8C F;  2I19 A;  3N0F A;  1HM4 A;  1N23 A;  4KVD A;  4KQ5 A;  1UBW A;  3Q1O A;  4QXS F;  3AQB B;  1WL1 A;  4LLT A;  5B0I A;  5B02 A;  5ILD A;  3WSA A;  4JZX A;  3WCH A;  5DJR F;  3ID0 A;  2E8V A;  3V1V A;  5IK9 A;  3WCE A;  5IVG A;  4HD1 A;  5ILJ A;  2OPM A;  4ZQ8 A;  4QPF A;  1VG4 A;  3N46 F;  4NFJ F;  4XQS F;  2Z4X A;  3EZ3 A;  3LK5 A;  5DJV F;  3WEF A;  2PS7 A;  3LOM A;  2AEL A;  2AZJ A;  1WY0 A;  5DGM F;  3AQ0 A;  3WCA A;  1KIY A;  2E90 A;  3TFN A;  1DGP A;  4KUX A;  4P0V A;  2ZEU A;  4F6X A;  4RYP A;  2Z7I A;  2E8W A;  3WEJ A;  2J1O A;  2EWG A;  3WCB A;  1V4H A;  2J1P A;  1YJ4 A;  4MC0 A;  1HXA A;  4DHD A;  2AEK A;  4H5E F;  3N45 F;  4RXA A;  3CC9 A;  3N1W F;  1UBY A;  2F9K F;  5ILI A;  5EAU A;  1V4K A;  4DEM F;  2J5C A;  3KRP A;  4E9Z A;  4LA6 A;  1RQJ A;  4F62 A;  5EAS A;  4RXC A;  1UBX A;  4DI5 A;  3AE0 A;  1HXC A;  2E92 A;  3NPR A;  3TFV A;  2VF6 A;  5ER8 A;  1N1B A;  2ZY1 A;  3M01 A;  3LZ9 A;  4RXD A;  1VG7 A;  3PDE A;  4KWD A;  3RYW A;  5B03 A;  2Z4W A;  3QQV A;  1YYR A;  3PH7 A;  3ZOU A;  3WCJ A;  4LTZ A;  1N20 A;  5IL3 A;  4P0X A;  1N21 A;  5AHU B;  3APZ A;  2Z7H A;  3KRA B;  2E8U A;  4NG6 A;  5IN8 A;  1V4I A;  3IPI A;  4N9U A;  4EA0 A;  5HN7 A;  2F94 F;  3LG5 A;  1DI1 A;  1YYS A;  2OGD A;  3ICK A;  4DZW A;  4H5D F;  2ONH A;  3KRC B;  4E9U A;  3P8L A;  2F89 F;  3DYG A;  3ACY A;  3P41 A;  4KQS A;  2Q9Z A;  4JXY A;  5ILY A;  3LGZ B;  4NFI F;  3S4J A;  1HX9 A;  3V1X A;  4EA1 A;  3RBM A;  4PVY F;  4P0W A;  3M00 A;  4LZ3 A;  3LGK A;  4DWG A;  4GAX A;  4H5C F;  3G4F A;  4KFA A;  5A0J A;  3Q2Z A;  3LSN A;  1WL3 A;  3WE9 A;  4GA3 A;  5B01 A;  2PS4 A;  2E95 A;  3KRO B;  4JZB A;  4MC3 A;  3P5P A;  2Z4V A;  5IKA A;  2E4O A;  4PVX F;  3M9U A;  2PS6 A;  4UMJ A;  3VJC A;  4NKF A;  5JUZ F;  3RYE A;  3SDT A;  3EFQ A;  2E91 A;  3SDV A;  5DGS F;  5IMN A;  1V4E A;  4KVW A;  5IKH A;  4LOB A;  3VJ8 A;  3OAB A;  5CG6 A;  3WJO A;  1VG3 A;  5B0L A;  2P1C A;  5IMI A;  3WC9 A;  3BNX A;  4LTV A;  3PKO A;  4LXW A;  3MZV A;  3SDU A;  5IM1 A;  2Z50 A;  3VJ9 A;  4LFV F;  4KQU A;  5DGN F;  3EGT A;  3N5H F;  3DYF A;  4KVI A;  3WJN A;  1PS1 A;  3KRA A;  3Q30 A;  4KVY A;  3WCC A;  4K10 A;  3N1V F;  2FTZ A;  1YYT A;  5B0J A;  5ILK A;  5E8K A;  4F6V A;  4L2X F;  2AZL A;  5DHK A;  3PYA A;  3TS7 A;  4RNQ A;  1EZF A;  4FJQ A;  4KK2 A;  4DWB A;  5AYP A;  3W7F A;  3KBK A;  3WEH A;  5HN9 A;  1HXG A;  5HN8 A;  3N5J F;  1VG2 A;  5IK0 A;  2ZCR A;  3LLW A;  5JA0 F;  2ZEV A;  5JV0 F;  4LIX A;  2ZCQ A;  4NFK F;  5AEL A;  4JVJ F;  3NF2 A;  3N0G A;  1WL0 A;  2OPN A;  3SDQ A;  4LFG A;  3ICM A;  4XQR F;  1YHM A;  4OMG A;  3P8R A;  2E94 A;  3WCL A;  3KRO A;  3IBA A;  3KB9 A;  3VJA A;  3B7L A;  5A0I A;  2F8Z F;  3N3L F;  3ZMC A;  3P5R A;  3LJI A;  4E1E A;  2ONG A;  2ZCS A;  5ILH A;  5KSX F;  5I1U A;  1WMW A;  5DW7 A;  1WL2 A;  1YV5 A;  5B00 A;  3N3D A;  3UCA A;  3OAC B;  4KKM A;  3OYR A;  3WEG A;  3WEI A;  2F92 F;  4Q23 A;  5JV1 F;  3WSB A;  3N6K F;  4FP4 A;  2AET A;  5DJP F;  1VG6 A;  2Z78 A;  3CP6 A;  3NRI A;  2O1O A;  3AQC B;  3RMG A;  4MC8 A;  3KRF B;  1UBV A;  4N1Z F;  3M0G A;  5H9D A;  3G4D A;  2Z4Z A;  3SAE A;  1YHL A;  2FOR A;  5IL8 A;  4JYX A;  3ICZ A;  1YHK A;  3ACX A;  3VJB A;  2H8O A;  4LZC A;  2AZK A;  1WKZ A;  4KPD A;  3WEK A;  2F7M F;  2OA6 A;  1V4J A;  3PYB A;  1RQI A;  4KPJ A;  3TC1 A;  2Z52 A;  5IK6 A;  3VJE A;  3N49 F;  3MAV A;  3VJD A;  3WCI A;  3LEE A;  2Q58 A;  4LPH F;  3Q2Q A;  5A0K A;  1FPS A;  3TFP A;  3QKC A;  3KRC A;  1N24 A;  4OKZ A;  3ZCD A;  2ZCO A;  5ILZ A;  5ERO A;  5HNA A;  3ZL6 A;  4DXJ A;  5IMP A;  3OAC A;  2Q80 A;  2E8X A;  4XQT F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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