4N1ZF

Crystal structure of human farnesyl diphosphate synthase in complex with bph-1222
Total Genus 127
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
127
sequence length
340
structure length
333
Chain Sequence
VYAQEKQDFVQHFSQIVRVLTHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords Farnesyl pyrophosphate synthase
publication title A combination therapy for KRAS-driven lung adenocarcinomas using lipophilic bisphosphonates and rapamycin.
pubmed doi rcsb
source organism Homo sapiens
total genus 127
structure length 333
sequence length 340
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2013-10-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4n1zF00
1N23A 4LOBA 2F9KF 1JFGA 1JFAA 3EFQA 2Z4ZA 2EWGA 4KK2A 2Z7HA 1YHKA 3MZVA 4F62A 5ILZA 4MC8A 4E1EA 1RTRA 1YHLA 5B0JA 3RYEA 5AFXA 3KRCB 3WEIA 3EZ3A 4PVXF 4DWGA 3ZCDA 5ER8A 4H5CF 2Z4YA 3LOMA 3KRCA 3P8RA 4Q23A 5DHKA 3RBMA 5B0KA 3V1XA 3SDQA 3PKOA 3EGTA 2J5CA 2E90A 5JV2F 3S9VA 4DHDA 3LK5A 3N45F 3OABB 4P0XA 5DJVF 5IMPA 4LTZA 3WCCA 3WC9A 1YYTA 3SDUA 1VG2A 2E8WA 4LTVA 3CKEA 4RXDA 2Z4XA 3ASXA 1UBXA 1HX9A 2Z78A 3P41A 3M01A 4KVWA 2Z4WA 3MAVA 3NRIA 3KBKA 1N1ZA 1N22A 4F6XA 3M02A 3NF2A 3WSBA 1PS1A 3Q2QA 4RXAA 3WCEA 3SDVA 2E8VA 4FP4A 5A0KA 5DIQF 4KVIA 3OYRA 4EA2A 3KRPB 3QKCA 3DYHA 3LSNA 3CP6A 1N24A 2E92A 2DH4A 4L2XF 4LFGA 1YQ7A 3DYFA 3VJEA 4FJQA 3ICMA 5E8HA 5C05A 4DXJA 3KROB 4LPGF 2ZCSA 5B0LA 1YV5A 5ILDA 3LG5A 3OACA 4N1ZF 4NG6A 3TC1A 2PS7A 4RXEA 4NFKF 3VJBA 1EZFA 1KIYA 3N0FA 1HXGA 5B00A 2FORA 4QPFA 5B0MA 3AE0A 4EA0A 5ILIA 5JUZF 3WCLA 2Q9YA 1N1BA 2F8CF 4H5EF 3W7FA 1V4IA 5ILYA 2I19A 5IN8A 5DGMF 4LFVF 4EA1A 3WEKA 3CC9A 3PH7A 4MC0A 3ZOUA 3WCMA 2ONGA 1RQJA 5DGNF 4KQUA 5CG5A 2Z50A 3RYWA 4LZ0A 4NFIF 4XQTF 3UCAA 2E8TA 1DGPA 4F6VA 3WJKA 5IVGA 2ZCOA 4KPDA 2PS5A 1YYQA 4DZWA 5IKHA 3N3DA 2E91A 1WL0A 4GP1A 2F92F 5ILKA 3QQVA 2H8OA 3Q1OA 5AELA 3WE9A 1DI1A 5ERMA 4NUAA 4LPHF 4ZQ8A 2P1CA 3KRFA 4KQSA 4XQSF 3N1VF 5A0IA 3LDWA 1UBYA 3DYGA 2E4OA 2OGDA 3WEGA 3P5RA 1V4HA 5EASA 4JXNA 3KB9A 5DGSF 3BNYA 3P8LA 3N0GA 3V1VA 5B02A 3WCGA 4LA6A 3S4JA 2F89F 3VJDA 2Z4VA 4JZXA 5JV0F 3N49F 5EAUA 3WCBA 4LA5A 3TFPA 3ICNA 3N5JF 3TFVA 4P0VA 4JVJF 5KSXF 3ACWA 3APZA 3M9UA 5A0JA 3WJNA 4P0WA 4RXCA 2E8XA 1N20A 2AEKA 3WCDA 3WEJA 5AHUB 2AZLA 3OACB 4UMJA 3BNXA 1YHMA 3ICZA 1YYUA 3TS7A 3LLWA 5E8LA 1KIZA 5IK6A 3VJCA 2E93A 3LGZB 5IMNA 1N21A 3ZL6A 1YYRA 2J1PA 2ZEVA 1V4EA 2F8ZF 4LUUA 2Q9ZA 3N3LF 2F94F 3ACYA 2PS6A 4GAXA 3AQ0A 4E9ZA 3Q2ZA 1V4KA 4KKMA 1FPSA 3ADZA 1ZW5A 2Q80A 4E9UA 2AZJA 3RMGA 4PVYF 3P5PA 5IM1A 4JZBA 5IL8A 4OGUA 3Q30A 1UBVA 4HD1A 3PYAA 5IK9A 3N1WF 4KVYA 5IKAA 3VJ9A 2OPMA 5B01A 2ZCRA 4QXSF 3G4DA 3WEFA 4JYXA 2PS4A 4LZ3A 5DJRF 5B0IA 3VJAA 3LEEA 3SAEA 3SDTA 2J1OA 5I1UA 2ZCQA 3N6KF 4GP2A 1VG7A 2F7MF 4DEMF 5ERNA 5HN9A 1HM4A 2FTZA 1RQIA 3KRFB 4WK5A 1VG3A 5DZ2A 5HNAA 2ONHA 1VG4A 4KQ5A 4NKFA 3LJIA 4JXYA 3LVSA 4RNQA 5E8KA 5AYPA 3VJ8A 1V4JA 2ZEUA 5HN8A 4OKMA 4GA3A 4LFEA 4NFJF 5EROA 2OA6A 2OPNA 3OABA 3WEHA 1YJ4A 5IK0A 3KRAB 3WCAA 3G4FA 1WY0A 4H5DF 5JA0F 3M00A 4OMGA 1YYSA 3ID0A 3IPIA 3KRAA 5IL3A 2E94A 4KPJA 3LZ9A 5JV1F 5H9DA 3ICKA 4LIXA 2RAHA 4OKZA 2VF6A 2AETA 5DW7A 3N5HF 4OMHA 3NPRA 3B7LA 4XQRF 3WCHA 3WJOA 3WSAA 1WL2A 4DI5A 2E95A 1HXAA 4LLTA 3LGKA 4NKEA 4KFAA 5EATA 4LLSA 1HXCA 2Z7IA 1WL3A 2O1OA 4LXWA 2PS8A 2AELA 2Z52A 3PDEA 3KRPA 2ZY1A 4K10A 5IMIA 4KVDA 3WCIA 3ZMBA 2AZKA 2E8UA 4N9UA 1WL1A 4MC3A 5DHIA 1WKZA 5B03A 5CG6A 3LMDA 4KWDA 4KUXA 1VG6A 3N46F 5ILJA 4DWBA 3KROA 5ILHA 3PYBA 3SDRA 5DJPF 1UBWA 3M0GA 3AQCB 3ZMCA 4LZCA 4RYPA 3WCFA 3NPKA 3V66A 2Q58A 2QISA 5HN7A 3TFNA 3ACXA 3IBAA 3WCJA 1HM7A 3AQBB 1WMWA
chains in the Genus database with same CATH superfamily
1N23A 4LOBA 2F9KF 1JFGA 1JFAA 3EFQA 2Z4ZA 2EWGA 4KK2A 2Z7HA 1YHKA 3MZVA 4F62A 5ILZA 4MC8A 4E1EA 1RTRA 1YHLA 5B0JA 3RYEA 5AFXA 3KRCB 3WEIA 3EZ3A 4PVXF 4DWGA 3ZCDA 5ER8A 4H5CF 2Z4YA 3LOMA 3KRCA 3P8RA 4Q23A 5DHKA 3RBMA 5B0KA 3V1XA 3SDQA 3PKOA 3EGTA 2J5CA 2E90A 5JV2F 3S9VA 4DHDA 3LK5A 3N45F 3OABB 4P0XA 5DJVF 5IMPA 4LTZA 3WCCA 3WC9A 1YYTA 3SDUA 1VG2A 2E8WA 4LTVA 3CKEA 4RXDA 2Z4XA 3ASXA 1UBXA 1HX9A 2Z78A 3P41A 3M01A 4KVWA 2Z4WA 3MAVA 3NRIA 3KBKA 1N1ZA 1N22A 4F6XA 3M02A 3NF2A 3WSBA 1PS1A 3Q2QA 4RXAA 3WCEA 3SDVA 2E8VA 4FP4A 5A0KA 5DIQF 4KVIA 3OYRA 4EA2A 3KRPB 3QKCA 3DYHA 3LSNA 3CP6A 1N24A 2E92A 2DH4A 4L2XF 4LFGA 1YQ7A 3DYFA 3VJEA 4FJQA 3ICMA 5E8HA 5C05A 4DXJA 3KROB 4LPGF 2ZCSA 5B0LA 1YV5A 5ILDA 3LG5A 3OACA 4N1ZF 4NG6A 3TC1A 2PS7A 4RXEA 4NFKF 3VJBA 1EZFA 1KIYA 3N0FA 1HXGA 5B00A 2FORA 4QPFA 5B0MA 3AE0A 4EA0A 5ILIA 5JUZF 3WCLA 2Q9YA 1N1BA 2F8CF 4H5EF 3W7FA 1V4IA 5ILYA 2I19A 5IN8A 5DGMF 4LFVF 4EA1A 3WEKA 3CC9A 3PH7A 4MC0A 3ZOUA 3WCMA 2ONGA 1RQJA 5DGNF 4KQUA 5CG5A 2Z50A 3RYWA 4LZ0A 4NFIF 4XQTF 3UCAA 2E8TA 1DGPA 4F6VA 3WJKA 5IVGA 2ZCOA 4KPDA 2PS5A 1YYQA 4DZWA 5IKHA 3N3DA 2E91A 1WL0A 4GP1A 2F92F 5ILKA 3QQVA 2H8OA 3Q1OA 5AELA 3WE9A 1DI1A 5ERMA 4NUAA 4LPHF 4ZQ8A 2P1CA 3KRFA 4KQSA 4XQSF 3N1VF 5A0IA 3LDWA 1UBYA 3DYGA 2E4OA 2OGDA 3WEGA 3P5RA 1V4HA 5EASA 4JXNA 3KB9A 5DGSF 3BNYA 3P8LA 3N0GA 3V1VA 5B02A 3WCGA 4LA6A 3S4JA 2F89F 3VJDA 2Z4VA 4JZXA 5JV0F 3N49F 5EAUA 3WCBA 4LA5A 3TFPA 3ICNA 3N5JF 3TFVA 4P0VA 4JVJF 5KSXF 3ACWA 3APZA 3M9UA 5A0JA 3WJNA 4P0WA 4RXCA 2E8XA 1N20A 2AEKA 3WCDA 3WEJA 5AHUB 2AZLA 3OACB 4UMJA 3BNXA 1YHMA 3ICZA 1YYUA 3TS7A 3LLWA 5E8LA 1KIZA 5IK6A 3VJCA 2E93A 3LGZB 5IMNA 1N21A 3ZL6A 1YYRA 2J1PA 2ZEVA 1V4EA 2F8ZF 4LUUA 2Q9ZA 3N3LF 2F94F 3ACYA 2PS6A 4GAXA 3AQ0A 4E9ZA 3Q2ZA 1V4KA 4KKMA 1FPSA 3ADZA 1ZW5A 2Q80A 4E9UA 2AZJA 3RMGA 4PVYF 3P5PA 5IM1A 4JZBA 5IL8A 4OGUA 3Q30A 1UBVA 4HD1A 3PYAA 5IK9A 3N1WF 4KVYA 5IKAA 3VJ9A 2OPMA 5B01A 2ZCRA 4QXSF 3G4DA 3WEFA 4JYXA 2PS4A 4LZ3A 5DJRF 5B0IA 3VJAA 3LEEA 3SAEA 3SDTA 2J1OA 5I1UA 2ZCQA 3N6KF 4GP2A 1VG7A 2F7MF 4DEMF 5ERNA 5HN9A 1HM4A 2FTZA 1RQIA 3KRFB 4WK5A 1VG3A 5DZ2A 5HNAA 2ONHA 1VG4A 4KQ5A 4NKFA 3LJIA 4JXYA 3LVSA 4RNQA 5E8KA 5AYPA 3VJ8A 1V4JA 2ZEUA 5HN8A 4OKMA 4GA3A 4LFEA 4NFJF 5EROA 2OA6A 2OPNA 3OABA 3WEHA 1YJ4A 5IK0A 3KRAB 3WCAA 3G4FA 1WY0A 4H5DF 5JA0F 3M00A 4OMGA 1YYSA 3ID0A 3IPIA 3KRAA 5IL3A 2E94A 4KPJA 3LZ9A 5JV1F 5H9DA 3ICKA 4LIXA 2RAHA 4OKZA 2VF6A 2AETA 5DW7A 3N5HF 4OMHA 3NPRA 3B7LA 4XQRF 3WCHA 3WJOA 3WSAA 1WL2A 4DI5A 2E95A 1HXAA 4LLTA 3LGKA 4NKEA 4KFAA 5EATA 4LLSA 1HXCA 2Z7IA 1WL3A 2O1OA 4LXWA 2PS8A 2AELA 2Z52A 3PDEA 3KRPA 2ZY1A 4K10A 5IMIA 4KVDA 3WCIA 3ZMBA 2AZKA 2E8UA 4N9UA 1WL1A 4MC3A 5DHIA 1WKZA 5B03A 5CG6A 3LMDA 4KWDA 4KUXA 1VG6A 3N46F 5ILJA 4DWBA 3KROA 5ILHA 3PYBA 3SDRA 5DJPF 1UBWA 3M0GA 3AQCB 3ZMCA 4LZCA 4RYPA 3WCFA 3NPKA 3V66A 2Q58A 2QISA 5HN7A 3TFNA 3ACXA 3IBAA 3WCJA 1HM7A 3AQBB 1WMWA
chains in the Genus database with same CATH topology
1N23A 4LOBA 2F9KF 1JFGA 1JFAA 3EFQA 2Z4ZA 2EWGA 4KK2A 2Z7HA 1YHKA 3MZVA 4F62A 5ILZA 4MC8A 4E1EA 1RTRA 1YHLA 5B0JA 3RYEA 5AFXA 3KRCB 3WEIA 3EZ3A 4PVXF 4DWGA 3ZCDA 5ER8A 4H5CF 2Z4YA 3LOMA 3KRCA 3P8RA 4Q23A 5DHKA 3RBMA 5B0KA 3V1XA 3SDQA 3PKOA 3EGTA 2J5CA 2E90A 5JV2F 3S9VA 4DHDA 3LK5A 3N45F 3OABB 4P0XA 5DJVF 5IMPA 4LTZA 3WCCA 3WC9A 1YYTA 3SDUA 1VG2A 2E8WA 4LTVA 3CKEA 4RXDA 2Z4XA 3ASXA 1UBXA 1HX9A 2Z78A 3P41A 3M01A 4KVWA 2Z4WA 3MAVA 3NRIA 3KBKA 1N1ZA 1N22A 4F6XA 3M02A 3NF2A 3WSBA 1PS1A 3Q2QA 4RXAA 3WCEA 3SDVA 2E8VA 4FP4A 5A0KA 5DIQF 4KVIA 3OYRA 4EA2A 3KRPB 3QKCA 3DYHA 3LSNA 3CP6A 1N24A 2E92A 2DH4A 4L2XF 4LFGA 1YQ7A 3DYFA 3VJEA 4FJQA 3ICMA 5E8HA 5C05A 4DXJA 3KROB 4LPGF 2ZCSA 5B0LA 1YV5A 5ILDA 3LG5A 3OACA 4N1ZF 4NG6A 3TC1A 2PS7A 4RXEA 4NFKF 3VJBA 1EZFA 1KIYA 3N0FA 1HXGA 5B00A 2FORA 4QPFA 5B0MA 3AE0A 4EA0A 5ILIA 5JUZF 3WCLA 2Q9YA 1N1BA 2F8CF 4H5EF 3W7FA 1V4IA 5ILYA 2I19A 5IN8A 5DGMF 4LFVF 4EA1A 3WEKA 3CC9A 3PH7A 4MC0A 3ZOUA 3WCMA 2ONGA 1RQJA 5DGNF 4KQUA 5CG5A 2Z50A 3RYWA 4LZ0A 4NFIF 4XQTF 3UCAA 2E8TA 1DGPA 4F6VA 3WJKA 5IVGA 2ZCOA 4KPDA 2PS5A 1YYQA 4DZWA 5IKHA 3N3DA 2E91A 1WL0A 4GP1A 2F92F 5ILKA 3QQVA 2H8OA 3Q1OA 5AELA 3WE9A 1DI1A 5ERMA 4NUAA 4LPHF 4ZQ8A 2P1CA 3KRFA 4KQSA 4XQSF 3N1VF 5A0IA 3LDWA 1UBYA 3DYGA 2E4OA 2OGDA 3WEGA 3P5RA 1V4HA 5EASA 4JXNA 3KB9A 5DGSF 3BNYA 3P8LA 3N0GA 3V1VA 5B02A 3WCGA 4LA6A 3S4JA 2F89F 3VJDA 2Z4VA 4JZXA 5JV0F 3N49F 5EAUA 3WCBA 4LA5A 3TFPA 3ICNA 3N5JF 3TFVA 4P0VA 4JVJF 5KSXF 3ACWA 3APZA 3M9UA 5A0JA 3WJNA 4P0WA 4RXCA 2E8XA 1N20A 2AEKA 3WCDA 3WEJA 5AHUB 2AZLA 3OACB 4UMJA 3BNXA 1YHMA 3ICZA 1YYUA 3TS7A 3LLWA 5E8LA 1KIZA 5IK6A 3VJCA 2E93A 3LGZB 5IMNA 1N21A 3ZL6A 1YYRA 2J1PA 2ZEVA 1V4EA 2F8ZF 4LUUA 2Q9ZA 3N3LF 2F94F 3ACYA 2PS6A 4GAXA 3AQ0A 4E9ZA 3Q2ZA 1V4KA 4KKMA 1FPSA 3ADZA 1ZW5A 2Q80A 4E9UA 2AZJA 3RMGA 4PVYF 3P5PA 5IM1A 4JZBA 5IL8A 4OGUA 3Q30A 1UBVA 4HD1A 3PYAA 5IK9A 3N1WF 4KVYA 5IKAA 3VJ9A 2OPMA 5B01A 2ZCRA 4QXSF 3G4DA 3WEFA 4JYXA 2PS4A 4LZ3A 5DJRF 5B0IA 3VJAA 3LEEA 3SAEA 3SDTA 2J1OA 5I1UA 2ZCQA 3N6KF 4GP2A 1VG7A 2F7MF 4DEMF 5ERNA 5HN9A 1HM4A 2FTZA 1RQIA 3KRFB 4WK5A 1VG3A 5DZ2A 5HNAA 2ONHA 1VG4A 4KQ5A 4NKFA 3LJIA 4JXYA 3LVSA 4RNQA 5E8KA 5AYPA 3VJ8A 1V4JA 2ZEUA 5HN8A 4OKMA 4GA3A 4LFEA 4NFJF 5EROA 2OA6A 2OPNA 3OABA 3WEHA 1YJ4A 5IK0A 3KRAB 3WCAA 3G4FA 1WY0A 4H5DF 5JA0F 3M00A 4OMGA 1YYSA 3ID0A 3IPIA 3KRAA 5IL3A 2E94A 4KPJA 3LZ9A 5JV1F 5H9DA 3ICKA 4LIXA 2RAHA 4OKZA 2VF6A 2AETA 5DW7A 3N5HF 4OMHA 3NPRA 3B7LA 4XQRF 3WCHA 3WJOA 3WSAA 1WL2A 4DI5A 2E95A 1HXAA 4LLTA 3LGKA 4NKEA 4KFAA 5EATA 4LLSA 1HXCA 2Z7IA 1WL3A 2O1OA 4LXWA 2PS8A 2AELA 2Z52A 3PDEA 3KRPA 2ZY1A 4K10A 5IMIA 4KVDA 3WCIA 3ZMBA 2AZKA 2E8UA 4N9UA 1WL1A 4MC3A 5DHIA 1WKZA 5B03A 5CG6A 3LMDA 4KWDA 4KUXA 1VG6A 3N46F 5ILJA 4DWBA 3KROA 5ILHA 3PYBA 3SDRA 5DJPF 1UBWA 3M0GA 3AQCB 3ZMCA 4LZCA 4RYPA 3WCFA 3NPKA 3V66A 2Q58A 2QISA 5HN7A 3TFNA 3ACXA 3IBAA 3WCJA 1HM7A 3AQBB 1WMWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1N23 A;  4LOB A;  2F9K F;  1JFG A;  1JFA A;  3EFQ A;  2Z4Z A;  2EWG A;  4KK2 A;  2Z7H A;  1YHK A;  3MZV A;  4F62 A;  5ILZ A;  4MC8 A;  4E1E A;  1RTR A;  1YHL A;  5B0J A;  3RYE A;  5AFX A;  3KRC B;  3WEI A;  3EZ3 A;  4PVX F;  4DWG A;  3ZCD A;  5ER8 A;  4H5C F;  2Z4Y A;  3LOM A;  3KRC A;  3P8R A;  4Q23 A;  5DHK A;  3RBM A;  5B0K A;  3V1X A;  3SDQ A;  3PKO A;  3EGT A;  2J5C A;  2E90 A;  5JV2 F;  3S9V A;  4DHD A;  3LK5 A;  3N45 F;  3OAB B;  4P0X A;  5DJV F;  5IMP A;  4LTZ A;  3WCC A;  3WC9 A;  1YYT A;  3SDU A;  1VG2 A;  2E8W A;  4LTV A;  3CKE A;  4RXD A;  2Z4X A;  3ASX A;  1UBX A;  1HX9 A;  2Z78 A;  3P41 A;  3M01 A;  4KVW A;  2Z4W A;  3MAV A;  3NRI A;  3KBK A;  1N1Z A;  1N22 A;  4F6X A;  3M02 A;  3NF2 A;  3WSB A;  1PS1 A;  3Q2Q A;  4RXA A;  3WCE A;  3SDV A;  2E8V A;  4FP4 A;  5A0K A;  5DIQ F;  4KVI A;  3OYR A;  4EA2 A;  3KRP B;  3QKC A;  3DYH A;  3LSN A;  3CP6 A;  1N24 A;  2E92 A;  2DH4 A;  4L2X F;  4LFG A;  1YQ7 A;  3DYF A;  3VJE A;  4FJQ A;  3ICM A;  5E8H A;  5C05 A;  4DXJ A;  3KRO B;  4LPG F;  2ZCS A;  5B0L A;  1YV5 A;  5ILD A;  3LG5 A;  3OAC A;  4N1Z F;  4NG6 A;  3TC1 A;  2PS7 A;  4RXE A;  4NFK F;  3VJB A;  1EZF A;  1KIY A;  3N0F A;  1HXG A;  5B00 A;  2FOR A;  4QPF A;  5B0M A;  3AE0 A;  4EA0 A;  5ILI A;  5JUZ F;  3WCL A;  2Q9Y A;  1N1B A;  2F8C F;  4H5E F;  3W7F A;  1V4I A;  5ILY A;  2I19 A;  5IN8 A;  5DGM F;  4LFV F;  4EA1 A;  3WEK A;  3CC9 A;  3PH7 A;  4MC0 A;  3ZOU A;  3WCM A;  2ONG A;  1RQJ A;  5DGN F;  4KQU A;  5CG5 A;  2Z50 A;  3RYW A;  4LZ0 A;  4NFI F;  4XQT F;  3UCA A;  2E8T A;  1DGP A;  4F6V A;  3WJK A;  5IVG A;  2ZCO A;  4KPD A;  2PS5 A;  1YYQ A;  4DZW A;  5IKH A;  3N3D A;  2E91 A;  1WL0 A;  4GP1 A;  2F92 F;  5ILK A;  3QQV A;  2H8O A;  3Q1O A;  5AEL A;  3WE9 A;  1DI1 A;  5ERM A;  4NUA A;  4LPH F;  4ZQ8 A;  2P1C A;  3KRF A;  4KQS A;  4XQS F;  3N1V F;  5A0I A;  3LDW A;  1UBY A;  3DYG A;  2E4O A;  2OGD A;  3WEG A;  3P5R A;  1V4H A;  5EAS A;  4JXN A;  3KB9 A;  5DGS F;  3BNY A;  3P8L A;  3N0G A;  3V1V A;  5B02 A;  3WCG A;  4LA6 A;  3S4J A;  2F89 F;  3VJD A;  2Z4V A;  4JZX A;  5JV0 F;  3N49 F;  5EAU A;  3WCB A;  4LA5 A;  3TFP A;  3ICN A;  3N5J F;  3TFV A;  4P0V A;  4JVJ F;  5KSX F;  3ACW A;  3APZ A;  3M9U A;  5A0J A;  3WJN A;  4P0W A;  4RXC A;  2E8X A;  1N20 A;  2AEK A;  3WCD A;  3WEJ A;  5AHU B;  2AZL A;  3OAC B;  4UMJ A;  3BNX A;  1YHM A;  3ICZ A;  1YYU A;  3TS7 A;  3LLW A;  5E8L A;  1KIZ A;  5IK6 A;  3VJC A;  2E93 A;  3LGZ B;  5IMN A;  1N21 A;  3ZL6 A;  1YYR A;  2J1P A;  2ZEV A;  1V4E A;  2F8Z F;  4LUU A;  2Q9Z A;  3N3L F;  2F94 F;  3ACY A;  2PS6 A;  4GAX A;  3AQ0 A;  4E9Z A;  3Q2Z A;  1V4K A;  4KKM A;  1FPS A;  3ADZ A;  1ZW5 A;  2Q80 A;  4E9U A;  2AZJ A;  3RMG A;  4PVY F;  3P5P A;  5IM1 A;  4JZB A;  5IL8 A;  4OGU A;  3Q30 A;  1UBV A;  4HD1 A;  3PYA A;  5IK9 A;  3N1W F;  4KVY A;  5IKA A;  3VJ9 A;  2OPM A;  5B01 A;  2ZCR A;  4QXS F;  3G4D A;  3WEF A;  4JYX A;  2PS4 A;  4LZ3 A;  5DJR F;  5B0I A;  3VJA A;  3LEE A;  3SAE A;  3SDT A;  2J1O A;  5I1U A;  2ZCQ A;  3N6K F;  4GP2 A;  1VG7 A;  2F7M F;  4DEM F;  5ERN A;  5HN9 A;  1HM4 A;  2FTZ A;  1RQI A;  3KRF B;  4WK5 A;  1VG3 A;  5DZ2 A;  5HNA A;  2ONH A;  1VG4 A;  4KQ5 A;  4NKF A;  3LJI A;  4JXY A;  3LVS A;  4RNQ A;  5E8K A;  5AYP A;  3VJ8 A;  1V4J A;  2ZEU A;  5HN8 A;  4OKM A;  4GA3 A;  4LFE A;  4NFJ F;  5ERO A;  2OA6 A;  2OPN A;  3OAB A;  3WEH A;  1YJ4 A;  5IK0 A;  3KRA B;  3WCA A;  3G4F A;  1WY0 A;  4H5D F;  5JA0 F;  3M00 A;  4OMG A;  1YYS A;  3ID0 A;  3IPI A;  3KRA A;  5IL3 A;  2E94 A;  4KPJ A;  3LZ9 A;  5JV1 F;  5H9D A;  3ICK A;  4LIX A;  2RAH A;  4OKZ A;  2VF6 A;  2AET A;  5DW7 A;  3N5H F;  4OMH A;  3NPR A;  3B7L A;  4XQR F;  3WCH A;  3WJO A;  3WSA A;  1WL2 A;  4DI5 A;  2E95 A;  1HXA A;  4LLT A;  3LGK A;  4NKE A;  4KFA A;  5EAT A;  4LLS A;  1HXC A;  2Z7I A;  1WL3 A;  2O1O A;  4LXW A;  2PS8 A;  2AEL A;  2Z52 A;  3PDE A;  3KRP A;  2ZY1 A;  4K10 A;  5IMI A;  4KVD A;  3WCI A;  3ZMB A;  2AZK A;  2E8U A;  4N9U A;  1WL1 A;  4MC3 A;  5DHI A;  1WKZ A;  5B03 A;  5CG6 A;  3LMD A;  4KWD A;  4KUX A;  1VG6 A;  3N46 F;  5ILJ A;  4DWB A;  3KRO A;  5ILH A;  3PYB A;  3SDR A;  5DJP F;  1UBW A;  3M0G A;  3AQC B;  3ZMC A;  4LZC A;  4RYP A;  3WCF A;  3NPK A;  3V66 A;  2Q58 A;  2QIS A;  5HN7 A;  3TFN A;  3ACX A;  3IBA A;  3WCJ A;  1HM7 A;  3AQB B;  1WMW A; 
#chains in the Genus database with same CATH topology
 1N23 A;  4LOB A;  2F9K F;  1JFG A;  1JFA A;  3EFQ A;  2Z4Z A;  2EWG A;  4KK2 A;  2Z7H A;  1YHK A;  3MZV A;  4F62 A;  5ILZ A;  4MC8 A;  4E1E A;  1RTR A;  1YHL A;  5B0J A;  3RYE A;  5AFX A;  3KRC B;  3WEI A;  3EZ3 A;  4PVX F;  4DWG A;  3ZCD A;  5ER8 A;  4H5C F;  2Z4Y A;  3LOM A;  3KRC A;  3P8R A;  4Q23 A;  5DHK A;  3RBM A;  5B0K A;  3V1X A;  3SDQ A;  3PKO A;  3EGT A;  2J5C A;  2E90 A;  5JV2 F;  3S9V A;  4DHD A;  3LK5 A;  3N45 F;  3OAB B;  4P0X A;  5DJV F;  5IMP A;  4LTZ A;  3WCC A;  3WC9 A;  1YYT A;  3SDU A;  1VG2 A;  2E8W A;  4LTV A;  3CKE A;  4RXD A;  2Z4X A;  3ASX A;  1UBX A;  1HX9 A;  2Z78 A;  3P41 A;  3M01 A;  4KVW A;  2Z4W A;  3MAV A;  3NRI A;  3KBK A;  1N1Z A;  1N22 A;  4F6X A;  3M02 A;  3NF2 A;  3WSB A;  1PS1 A;  3Q2Q A;  4RXA A;  3WCE A;  3SDV A;  2E8V A;  4FP4 A;  5A0K A;  5DIQ F;  4KVI A;  3OYR A;  4EA2 A;  3KRP B;  3QKC A;  3DYH A;  3LSN A;  3CP6 A;  1N24 A;  2E92 A;  2DH4 A;  4L2X F;  4LFG A;  1YQ7 A;  3DYF A;  3VJE A;  4FJQ A;  3ICM A;  5E8H A;  5C05 A;  4DXJ A;  3KRO B;  4LPG F;  2ZCS A;  5B0L A;  1YV5 A;  5ILD A;  3LG5 A;  3OAC A;  4N1Z F;  4NG6 A;  3TC1 A;  2PS7 A;  4RXE A;  4NFK F;  3VJB A;  1EZF A;  1KIY A;  3N0F A;  1HXG A;  5B00 A;  2FOR A;  4QPF A;  5B0M A;  3AE0 A;  4EA0 A;  5ILI A;  5JUZ F;  3WCL A;  2Q9Y A;  1N1B A;  2F8C F;  4H5E F;  3W7F A;  1V4I A;  5ILY A;  2I19 A;  5IN8 A;  5DGM F;  4LFV F;  4EA1 A;  3WEK A;  3CC9 A;  3PH7 A;  4MC0 A;  3ZOU A;  3WCM A;  2ONG A;  1RQJ A;  5DGN F;  4KQU A;  5CG5 A;  2Z50 A;  3RYW A;  4LZ0 A;  4NFI F;  4XQT F;  3UCA A;  2E8T A;  1DGP A;  4F6V A;  3WJK A;  5IVG A;  2ZCO A;  4KPD A;  2PS5 A;  1YYQ A;  4DZW A;  5IKH A;  3N3D A;  2E91 A;  1WL0 A;  4GP1 A;  2F92 F;  5ILK A;  3QQV A;  2H8O A;  3Q1O A;  5AEL A;  3WE9 A;  1DI1 A;  5ERM A;  4NUA A;  4LPH F;  4ZQ8 A;  2P1C A;  3KRF A;  4KQS A;  4XQS F;  3N1V F;  5A0I A;  3LDW A;  1UBY A;  3DYG A;  2E4O A;  2OGD A;  3WEG A;  3P5R A;  1V4H A;  5EAS A;  4JXN A;  3KB9 A;  5DGS F;  3BNY A;  3P8L A;  3N0G A;  3V1V A;  5B02 A;  3WCG A;  4LA6 A;  3S4J A;  2F89 F;  3VJD A;  2Z4V A;  4JZX A;  5JV0 F;  3N49 F;  5EAU A;  3WCB A;  4LA5 A;  3TFP A;  3ICN A;  3N5J F;  3TFV A;  4P0V A;  4JVJ F;  5KSX F;  3ACW A;  3APZ A;  3M9U A;  5A0J A;  3WJN A;  4P0W A;  4RXC A;  2E8X A;  1N20 A;  2AEK A;  3WCD A;  3WEJ A;  5AHU B;  2AZL A;  3OAC B;  4UMJ A;  3BNX A;  1YHM A;  3ICZ A;  1YYU A;  3TS7 A;  3LLW A;  5E8L A;  1KIZ A;  5IK6 A;  3VJC A;  2E93 A;  3LGZ B;  5IMN A;  1N21 A;  3ZL6 A;  1YYR A;  2J1P A;  2ZEV A;  1V4E A;  2F8Z F;  4LUU A;  2Q9Z A;  3N3L F;  2F94 F;  3ACY A;  2PS6 A;  4GAX A;  3AQ0 A;  4E9Z A;  3Q2Z A;  1V4K A;  4KKM A;  1FPS A;  3ADZ A;  1ZW5 A;  2Q80 A;  4E9U A;  2AZJ A;  3RMG A;  4PVY F;  3P5P A;  5IM1 A;  4JZB A;  5IL8 A;  4OGU A;  3Q30 A;  1UBV A;  4HD1 A;  3PYA A;  5IK9 A;  3N1W F;  4KVY A;  5IKA A;  3VJ9 A;  2OPM A;  5B01 A;  2ZCR A;  4QXS F;  3G4D A;  3WEF A;  4JYX A;  2PS4 A;  4LZ3 A;  5DJR F;  5B0I A;  3VJA A;  3LEE A;  3SAE A;  3SDT A;  2J1O A;  5I1U A;  2ZCQ A;  3N6K F;  4GP2 A;  1VG7 A;  2F7M F;  4DEM F;  5ERN A;  5HN9 A;  1HM4 A;  2FTZ A;  1RQI A;  3KRF B;  4WK5 A;  1VG3 A;  5DZ2 A;  5HNA A;  2ONH A;  1VG4 A;  4KQ5 A;  4NKF A;  3LJI A;  4JXY A;  3LVS A;  4RNQ A;  5E8K A;  5AYP A;  3VJ8 A;  1V4J A;  2ZEU A;  5HN8 A;  4OKM A;  4GA3 A;  4LFE A;  4NFJ F;  5ERO A;  2OA6 A;  2OPN A;  3OAB A;  3WEH A;  1YJ4 A;  5IK0 A;  3KRA B;  3WCA A;  3G4F A;  1WY0 A;  4H5D F;  5JA0 F;  3M00 A;  4OMG A;  1YYS A;  3ID0 A;  3IPI A;  3KRA A;  5IL3 A;  2E94 A;  4KPJ A;  3LZ9 A;  5JV1 F;  5H9D A;  3ICK A;  4LIX A;  2RAH A;  4OKZ A;  2VF6 A;  2AET A;  5DW7 A;  3N5H F;  4OMH A;  3NPR A;  3B7L A;  4XQR F;  3WCH A;  3WJO A;  3WSA A;  1WL2 A;  4DI5 A;  2E95 A;  1HXA A;  4LLT A;  3LGK A;  4NKE A;  4KFA A;  5EAT A;  4LLS A;  1HXC A;  2Z7I A;  1WL3 A;  2O1O A;  4LXW A;  2PS8 A;  2AEL A;  2Z52 A;  3PDE A;  3KRP A;  2ZY1 A;  4K10 A;  5IMI A;  4KVD A;  3WCI A;  3ZMB A;  2AZK A;  2E8U A;  4N9U A;  1WL1 A;  4MC3 A;  5DHI A;  1WKZ A;  5B03 A;  5CG6 A;  3LMD A;  4KWD A;  4KUX A;  1VG6 A;  3N46 F;  5ILJ A;  4DWB A;  3KRO A;  5ILH A;  3PYB A;  3SDR A;  5DJP F;  1UBW A;  3M0G A;  3AQC B;  3ZMC A;  4LZC A;  4RYP A;  3WCF A;  3NPK A;  3V66 A;  2Q58 A;  2QIS A;  5HN7 A;  3TFN A;  3ACX A;  3IBA A;  3WCJ A;  1HM7 A;  3AQB B;  1WMW A; 
#chains in the Genus database with same CATH homology
 1N23 A;  4LOB A;  2F9K F;  1JFG A;  1JFA A;  3EFQ A;  2Z4Z A;  2EWG A;  4KK2 A;  2Z7H A;  1YHK A;  3MZV A;  4F62 A;  5ILZ A;  4MC8 A;  4E1E A;  1RTR A;  1YHL A;  5B0J A;  3RYE A;  5AFX A;  3KRC B;  3WEI A;  3EZ3 A;  4PVX F;  4DWG A;  3ZCD A;  5ER8 A;  4H5C F;  2Z4Y A;  3LOM A;  3KRC A;  3P8R A;  4Q23 A;  5DHK A;  3RBM A;  5B0K A;  3V1X A;  3SDQ A;  3PKO A;  3EGT A;  2J5C A;  2E90 A;  5JV2 F;  3S9V A;  4DHD A;  3LK5 A;  3N45 F;  3OAB B;  4P0X A;  5DJV F;  5IMP A;  4LTZ A;  3WCC A;  3WC9 A;  1YYT A;  3SDU A;  1VG2 A;  2E8W A;  4LTV A;  3CKE A;  4RXD A;  2Z4X A;  3ASX A;  1UBX A;  1HX9 A;  2Z78 A;  3P41 A;  3M01 A;  4KVW A;  2Z4W A;  3MAV A;  3NRI A;  3KBK A;  1N1Z A;  1N22 A;  4F6X A;  3M02 A;  3NF2 A;  3WSB A;  1PS1 A;  3Q2Q A;  4RXA A;  3WCE A;  3SDV A;  2E8V A;  4FP4 A;  5A0K A;  5DIQ F;  4KVI A;  3OYR A;  4EA2 A;  3KRP B;  3QKC A;  3DYH A;  3LSN A;  3CP6 A;  1N24 A;  2E92 A;  2DH4 A;  4L2X F;  4LFG A;  1YQ7 A;  3DYF A;  3VJE A;  4FJQ A;  3ICM A;  5E8H A;  5C05 A;  4DXJ A;  3KRO B;  4LPG F;  2ZCS A;  5B0L A;  1YV5 A;  5ILD A;  3LG5 A;  3OAC A;  4N1Z F;  4NG6 A;  3TC1 A;  2PS7 A;  4RXE A;  4NFK F;  3VJB A;  1EZF A;  1KIY A;  3N0F A;  1HXG A;  5B00 A;  2FOR A;  4QPF A;  5B0M A;  3AE0 A;  4EA0 A;  5ILI A;  5JUZ F;  3WCL A;  2Q9Y A;  1N1B A;  2F8C F;  4H5E F;  3W7F A;  1V4I A;  5ILY A;  2I19 A;  5IN8 A;  5DGM F;  4LFV F;  4EA1 A;  3WEK A;  3CC9 A;  3PH7 A;  4MC0 A;  3ZOU A;  3WCM A;  2ONG A;  1RQJ A;  5DGN F;  4KQU A;  5CG5 A;  2Z50 A;  3RYW A;  4LZ0 A;  4NFI F;  4XQT F;  3UCA A;  2E8T A;  1DGP A;  4F6V A;  3WJK A;  5IVG A;  2ZCO A;  4KPD A;  2PS5 A;  1YYQ A;  4DZW A;  5IKH A;  3N3D A;  2E91 A;  1WL0 A;  4GP1 A;  2F92 F;  5ILK A;  3QQV A;  2H8O A;  3Q1O A;  5AEL A;  3WE9 A;  1DI1 A;  5ERM A;  4NUA A;  4LPH F;  4ZQ8 A;  2P1C A;  3KRF A;  4KQS A;  4XQS F;  3N1V F;  5A0I A;  3LDW A;  1UBY A;  3DYG A;  2E4O A;  2OGD A;  3WEG A;  3P5R A;  1V4H A;  5EAS A;  4JXN A;  3KB9 A;  5DGS F;  3BNY A;  3P8L A;  3N0G A;  3V1V A;  5B02 A;  3WCG A;  4LA6 A;  3S4J A;  2F89 F;  3VJD A;  2Z4V A;  4JZX A;  5JV0 F;  3N49 F;  5EAU A;  3WCB A;  4LA5 A;  3TFP A;  3ICN A;  3N5J F;  3TFV A;  4P0V A;  4JVJ F;  5KSX F;  3ACW A;  3APZ A;  3M9U A;  5A0J A;  3WJN A;  4P0W A;  4RXC A;  2E8X A;  1N20 A;  2AEK A;  3WCD A;  3WEJ A;  5AHU B;  2AZL A;  3OAC B;  4UMJ A;  3BNX A;  1YHM A;  3ICZ A;  1YYU A;  3TS7 A;  3LLW A;  5E8L A;  1KIZ A;  5IK6 A;  3VJC A;  2E93 A;  3LGZ B;  5IMN A;  1N21 A;  3ZL6 A;  1YYR A;  2J1P A;  2ZEV A;  1V4E A;  2F8Z F;  4LUU A;  2Q9Z A;  3N3L F;  2F94 F;  3ACY A;  2PS6 A;  4GAX A;  3AQ0 A;  4E9Z A;  3Q2Z A;  1V4K A;  4KKM A;  1FPS A;  3ADZ A;  1ZW5 A;  2Q80 A;  4E9U A;  2AZJ A;  3RMG A;  4PVY F;  3P5P A;  5IM1 A;  4JZB A;  5IL8 A;  4OGU A;  3Q30 A;  1UBV A;  4HD1 A;  3PYA A;  5IK9 A;  3N1W F;  4KVY A;  5IKA A;  3VJ9 A;  2OPM A;  5B01 A;  2ZCR A;  4QXS F;  3G4D A;  3WEF A;  4JYX A;  2PS4 A;  4LZ3 A;  5DJR F;  5B0I A;  3VJA A;  3LEE A;  3SAE A;  3SDT A;  2J1O A;  5I1U A;  2ZCQ A;  3N6K F;  4GP2 A;  1VG7 A;  2F7M F;  4DEM F;  5ERN A;  5HN9 A;  1HM4 A;  2FTZ A;  1RQI A;  3KRF B;  4WK5 A;  1VG3 A;  5DZ2 A;  5HNA A;  2ONH A;  1VG4 A;  4KQ5 A;  4NKF A;  3LJI A;  4JXY A;  3LVS A;  4RNQ A;  5E8K A;  5AYP A;  3VJ8 A;  1V4J A;  2ZEU A;  5HN8 A;  4OKM A;  4GA3 A;  4LFE A;  4NFJ F;  5ERO A;  2OA6 A;  2OPN A;  3OAB A;  3WEH A;  1YJ4 A;  5IK0 A;  3KRA B;  3WCA A;  3G4F A;  1WY0 A;  4H5D F;  5JA0 F;  3M00 A;  4OMG A;  1YYS A;  3ID0 A;  3IPI A;  3KRA A;  5IL3 A;  2E94 A;  4KPJ A;  3LZ9 A;  5JV1 F;  5H9D A;  3ICK A;  4LIX A;  2RAH A;  4OKZ A;  2VF6 A;  2AET A;  5DW7 A;  3N5H F;  4OMH A;  3NPR A;  3B7L A;  4XQR F;  3WCH A;  3WJO A;  3WSA A;  1WL2 A;  4DI5 A;  2E95 A;  1HXA A;  4LLT A;  3LGK A;  4NKE A;  4KFA A;  5EAT A;  4LLS A;  1HXC A;  2Z7I A;  1WL3 A;  2O1O A;  4LXW A;  2PS8 A;  2AEL A;  2Z52 A;  3PDE A;  3KRP A;  2ZY1 A;  4K10 A;  5IMI A;  4KVD A;  3WCI A;  3ZMB A;  2AZK A;  2E8U A;  4N9U A;  1WL1 A;  4MC3 A;  5DHI A;  1WKZ A;  5B03 A;  5CG6 A;  3LMD A;  4KWD A;  4KUX A;  1VG6 A;  3N46 F;  5ILJ A;  4DWB A;  3KRO A;  5ILH A;  3PYB A;  3SDR A;  5DJP F;  1UBW A;  3M0G A;  3AQC B;  3ZMC A;  4LZC A;  4RYP A;  3WCF A;  3NPK A;  3V66 A;  2Q58 A;  2QIS A;  5HN7 A;  3TFN A;  3ACX A;  3IBA A;  3WCJ A;  1HM7 A;  3AQB B;  1WMW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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