4N1ZF

Crystal structure of human farnesyl diphosphate synthase in complex with bph-1222
Total Genus 127
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
127
sequence length
340
structure length
333
Chain Sequence
VYAQEKQDFVQHFSQIVRVLTHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Farnesyl pyrophosphate synthase
publication title A combination therapy for KRAS-driven lung adenocarcinomas using lipophilic bisphosphonates and rapamycin.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 127
structure length 333
sequence length 340
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2013-10-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4n1zF00
3N46F 3WEJA 3WSBA 3ASXA 3WCBA 2Z50A 3KRPB 3RBMA 2E91A 5DGNF 4KUXA 3KRFA 2ZEVA 4NUAA 2PS8A 3LVSA 1WY0A 3V1XA 3WJKA 3PKOA 3KRCA 1VG2A 3WEFA 4E1EA 4MC0A 3W7FA 4KVWA 1YYQA 2Z7IA 3G4DA 4Q23A 3PYBA 2OGDA 4LZCA 4LFGA 1RQIA 3VJ9A 4UMJA 4RXDA 5E8HA 2F89F 5IK6A 3VJAA 4LTVA 1YYRA 4MC8A 3N6KF 4L2XF 5B0MA 3EFQA 5ER8A 1ZW5A 5A0JA 3ACYA 2EWGA 3OACA 3NRIA 3EZ3A 5CG6A 4LIXA 5KSXF 5IL3A 3ZOUA 3WCFA 2AETA 4N1ZF 2J5CA 5CG5A 4KVDA 3PDEA 4RXEA 3P8RA 5EAUA 3ACWA 2E90A 4NFKF 4OMHA 4FP4A 5I1UA 4FJQA 5EASA 2ZCQA 2QISA 2E94A 3NPRA 3N3DA 4DXJA 2F7MF 3ICKA 1N21A 3OABB 1N1BA 5C05A 2AZJA 4KVIA 3NPKA 3IPIA 4GAXA 5ILDA 1V4HA 3ZL6A 1V4IA 3VJEA 4DZWA 3KRFB 1FPSA 5B00A 4F62A 4DWBA 1KIYA 5HN9A 1HX9A 4LZ0A 4XQRF 3P41A 3LK5A 4E9ZA 3LLWA 4H5CF 3KRCB 5DIQF 2PS4A 2ZCSA 4LFVF 3ICZA 4NFIF 3TFPA 5JV2F 4KKMA 3VJ8A 3WCJA 4MC3A 3BNXA 5DGSF 1V4KA 3B7LA 3WEGA 2VF6A 2E95A 4LFEA 3WCCA 2F8ZF 1DGPA 3WCHA 3KB9A 3CP6A 3LJIA 2ZCOA 2E4OA 1YJ4A 3ADZA 3N1VF 5ILZA 1UBWA 5IMIA 3SDRA 3RMGA 2ONHA 3Q2ZA 5IL8A 2E8UA 3P8LA 3WCIA 3OACB 2H8OA 1VG3A 3LMDA 3MZVA 4KPJA 3PH7A 4E9UA 2Q58A 5IVGA 5IM1A 4P0XA 2F8CF 4PVYF 3VJBA 5B0IA 3KROA 5DW7A 5ILIA 3SDQA 1VG6A 3AQBB 3TFNA 3SDVA 3Q2QA 5JV0F 4K10A 3ZCDA 5AELA 4N9UA 1HXGA 4LPHF 3LG5A 3AQ0A 2OA6A 3TS7A 5HN7A 3N45F 5DJRF 4P0VA 3G4FA 4KQ5A 3EGTA 1KIZA 4LUUA 4JZXA 4OKZA 4NKFA 3ZMBA 3WJOA 5IKAA 3NF2A 2FORA 3AQCB 3VJCA 2OPMA 3KRPA 1VG4A 4KPDA 4XQSF 3LOMA 3CC9A 3AE0A 4KQUA 2E93A 3UCAA 1YYSA 3N0FA 4F6XA 1YHKA 1WMWA 3RYEA 3BNYA 1YHMA 3KRAA 2Q9ZA 3ICNA 3SDUA 3M00A 4OMGA 5AHUB 5JA0F 4NG6A 4GA3A 2Z4YA 3LGKA 3ZMCA 3WCLA 1N20A 1YHLA 1V4JA 5E8LA 2DH4A 5IKHA 1N1ZA 2I19A 3VJDA 2E8XA 3WCMA 4XQTF 4KFAA 2Z52A 3ICMA 4HD1A 5E8KA 2P1CA 5HNAA 5JV1F 3QKCA 5IMPA 2Z4WA 3P5PA 5B0JA 3APZA 5B0KA 4DHDA 2Z7HA 2ZEUA 4KK2A 5IK0A 5DHKA 1HXCA 4KWDA 5EATA 3WEHA 3N5JF 1UBYA 3Q1OA 4KQSA 2AELA 5A0KA 3M01A 3RYWA 1YQ7A 1PS1A 3LDWA 3OABA 3IBAA 4JVJF 3V66A 2F9KF 3ACXA 3WJNA 1HXAA 3WE9A 3WCAA 4LPGF 3N49F 4DEMF 5ERNA 3N0GA 1N23A 5JUZF 2Z4ZA 2Z4XA 5EROA 1DI1A 2J1OA 3WEKA 5B01A 1WL3A 1YV5A 1HM7A 3WCEA 1HM4A 1EZFA 3KRAB 4PVXF 4LA6A 2Q9YA 5DJVF 2E8WA 4QXSF 1WKZA 3DYFA 4ZQ8A 4GP1A 2PS6A 3N5HF 4WK5A 4EA1A 2ONGA 3V1VA 3WSAA 1UBXA 4LLTA 4RXAA 3SDTA 5HN8A 1UBVA 1WL2A 3SAEA 4JXNA 4NKEA 3TFVA 2J1PA 2O1OA 5DHIA 3ID0A 4H5DF 1JFGA 4LTZA 4JYXA 3PYAA 4EA0A 5ILHA 2F94F 4H5EF 2RAHA 4P0WA 5ERMA 5ILJA 2Q80A 1N24A 1VG7A 4LLSA 3QQVA 3LEEA 5DGMF 2E8VA 2PS5A 3M0GA 3MAVA 3KBKA 5DJPF 5B02A 1N22A 2E92A 1YYUA 1V4EA 3TC1A 3LZ9A 3N3LF 3DYHA 4KVYA 2PS7A 1WL1A 3WEIA 3P5RA 5A0IA 2OPNA 1WL0A 5AYPA 4JXYA 4DI5A 5B0LA 3Q30A 4RXCA 4RYPA 3S4JA 3WCGA 4QPFA 4RNQA 4LZ3A 5IMNA 4GP2A 3N1WF 2Z78A 2AEKA 2Z4VA 4LXWA 3CKEA 4OKMA 5B03A 4EA2A 3KROB 2AZLA 4LA5A 4LOBA 5ILKA 4DWGA 3M02A 5H9DA 5AFXA 5DZ2A 5IN8A 4JZBA 2FTZA 5ILYA 2F92F 3OYRA 3WC9A 3LGZB 2ZY1A 2AZKA 1JFAA 5IK9A 3WCDA 2E8TA 4OGUA 4F6VA 1YYTA 3LSNA 1RTRA 3S9VA 1RQJA 4NFJF 3M9UA 3DYGA 2ZCRA
chains in the Genus database with same CATH superfamily
3N46F 3WEJA 3WSBA 3ASXA 3WCBA 2Z50A 3KRPB 3RBMA 2E91A 5DGNF 4KUXA 3KRFA 2ZEVA 4NUAA 2PS8A 3LVSA 1WY0A 3V1XA 3WJKA 3PKOA 3KRCA 1VG2A 3WEFA 4E1EA 4MC0A 3W7FA 4KVWA 1YYQA 2Z7IA 3G4DA 4Q23A 3PYBA 2OGDA 4LZCA 4LFGA 1RQIA 3VJ9A 4UMJA 4RXDA 5E8HA 2F89F 5IK6A 3VJAA 4LTVA 1YYRA 4MC8A 3N6KF 4L2XF 5B0MA 3EFQA 5ER8A 1ZW5A 5A0JA 3ACYA 2EWGA 3OACA 3NRIA 3EZ3A 5CG6A 4LIXA 5KSXF 5IL3A 3ZOUA 3WCFA 2AETA 4N1ZF 2J5CA 5CG5A 4KVDA 3PDEA 4RXEA 3P8RA 5EAUA 3ACWA 2E90A 4NFKF 4OMHA 4FP4A 5I1UA 4FJQA 5EASA 2ZCQA 2QISA 2E94A 3NPRA 3N3DA 4DXJA 2F7MF 3ICKA 1N21A 3OABB 1N1BA 5C05A 2AZJA 4KVIA 3NPKA 3IPIA 4GAXA 5ILDA 1V4HA 3ZL6A 1V4IA 3VJEA 4DZWA 3KRFB 1FPSA 5B00A 4F62A 4DWBA 1KIYA 5HN9A 1HX9A 4LZ0A 4XQRF 3P41A 3LK5A 4E9ZA 3LLWA 4H5CF 3KRCB 5DIQF 2PS4A 2ZCSA 4LFVF 3ICZA 4NFIF 3TFPA 5JV2F 4KKMA 3VJ8A 3WCJA 4MC3A 3BNXA 5DGSF 1V4KA 3B7LA 3WEGA 2VF6A 2E95A 4LFEA 3WCCA 2F8ZF 1DGPA 3WCHA 3KB9A 3CP6A 3LJIA 2ZCOA 2E4OA 1YJ4A 3ADZA 3N1VF 5ILZA 1UBWA 5IMIA 3SDRA 3RMGA 2ONHA 3Q2ZA 5IL8A 2E8UA 3P8LA 3WCIA 3OACB 2H8OA 1VG3A 3LMDA 3MZVA 4KPJA 3PH7A 4E9UA 2Q58A 5IVGA 5IM1A 4P0XA 2F8CF 4PVYF 3VJBA 5B0IA 3KROA 5DW7A 5ILIA 3SDQA 1VG6A 3AQBB 3TFNA 3SDVA 3Q2QA 5JV0F 4K10A 3ZCDA 5AELA 4N9UA 1HXGA 4LPHF 3LG5A 3AQ0A 2OA6A 3TS7A 5HN7A 3N45F 5DJRF 4P0VA 3G4FA 4KQ5A 3EGTA 1KIZA 4LUUA 4JZXA 4OKZA 4NKFA 3ZMBA 3WJOA 5IKAA 3NF2A 2FORA 3AQCB 3VJCA 2OPMA 3KRPA 1VG4A 4KPDA 4XQSF 3LOMA 3CC9A 3AE0A 4KQUA 2E93A 3UCAA 1YYSA 3N0FA 4F6XA 1YHKA 1WMWA 3RYEA 3BNYA 1YHMA 3KRAA 2Q9ZA 3ICNA 3SDUA 3M00A 4OMGA 5AHUB 5JA0F 4NG6A 4GA3A 2Z4YA 3LGKA 3ZMCA 3WCLA 1N20A 1YHLA 1V4JA 5E8LA 2DH4A 5IKHA 1N1ZA 2I19A 3VJDA 2E8XA 3WCMA 4XQTF 4KFAA 2Z52A 3ICMA 4HD1A 5E8KA 2P1CA 5HNAA 5JV1F 3QKCA 5IMPA 2Z4WA 3P5PA 5B0JA 3APZA 5B0KA 4DHDA 2Z7HA 2ZEUA 4KK2A 5IK0A 5DHKA 1HXCA 4KWDA 5EATA 3WEHA 3N5JF 1UBYA 3Q1OA 4KQSA 2AELA 5A0KA 3M01A 3RYWA 1YQ7A 1PS1A 3LDWA 3OABA 3IBAA 4JVJF 3V66A 2F9KF 3ACXA 3WJNA 1HXAA 3WE9A 3WCAA 4LPGF 3N49F 4DEMF 5ERNA 3N0GA 1N23A 5JUZF 2Z4ZA 2Z4XA 5EROA 1DI1A 2J1OA 3WEKA 5B01A 1WL3A 1YV5A 1HM7A 3WCEA 1HM4A 1EZFA 3KRAB 4PVXF 4LA6A 2Q9YA 5DJVF 2E8WA 4QXSF 1WKZA 3DYFA 4ZQ8A 4GP1A 2PS6A 3N5HF 4WK5A 4EA1A 2ONGA 3V1VA 3WSAA 1UBXA 4LLTA 4RXAA 3SDTA 5HN8A 1UBVA 1WL2A 3SAEA 4JXNA 4NKEA 3TFVA 2J1PA 2O1OA 5DHIA 3ID0A 4H5DF 1JFGA 4LTZA 4JYXA 3PYAA 4EA0A 5ILHA 2F94F 4H5EF 2RAHA 4P0WA 5ERMA 5ILJA 2Q80A 1N24A 1VG7A 4LLSA 3QQVA 3LEEA 5DGMF 2E8VA 2PS5A 3M0GA 3MAVA 3KBKA 5DJPF 5B02A 1N22A 2E92A 1YYUA 1V4EA 3TC1A 3LZ9A 3N3LF 3DYHA 4KVYA 2PS7A 1WL1A 3WEIA 3P5RA 5A0IA 2OPNA 1WL0A 5AYPA 4JXYA 4DI5A 5B0LA 3Q30A 4RXCA 4RYPA 3S4JA 3WCGA 4QPFA 4RNQA 4LZ3A 5IMNA 4GP2A 3N1WF 2Z78A 2AEKA 2Z4VA 4LXWA 3CKEA 4OKMA 5B03A 4EA2A 3KROB 2AZLA 4LA5A 4LOBA 5ILKA 4DWGA 3M02A 5H9DA 5AFXA 5DZ2A 5IN8A 4JZBA 2FTZA 5ILYA 2F92F 3OYRA 3WC9A 3LGZB 2ZY1A 2AZKA 1JFAA 5IK9A 3WCDA 2E8TA 4OGUA 4F6VA 1YYTA 3LSNA 1RTRA 3S9VA 1RQJA 4NFJF 3M9UA 3DYGA 2ZCRA
chains in the Genus database with same CATH topology
3N46F 3WEJA 3WSBA 3ASXA 3WCBA 2Z50A 3KRPB 3RBMA 2E91A 5DGNF 4KUXA 3KRFA 2ZEVA 4NUAA 2PS8A 3LVSA 1WY0A 3V1XA 3WJKA 3PKOA 3KRCA 1VG2A 3WEFA 4E1EA 4MC0A 3W7FA 4KVWA 1YYQA 2Z7IA 3G4DA 4Q23A 3PYBA 2OGDA 4LZCA 4LFGA 1RQIA 3VJ9A 4UMJA 4RXDA 5E8HA 2F89F 5IK6A 3VJAA 4LTVA 1YYRA 4MC8A 3N6KF 4L2XF 5B0MA 3EFQA 5ER8A 1ZW5A 5A0JA 3ACYA 2EWGA 3OACA 3NRIA 3EZ3A 5CG6A 4LIXA 5KSXF 5IL3A 3ZOUA 3WCFA 2AETA 4N1ZF 2J5CA 5CG5A 4KVDA 3PDEA 4RXEA 3P8RA 5EAUA 3ACWA 2E90A 4NFKF 4OMHA 4FP4A 5I1UA 4FJQA 5EASA 2ZCQA 2QISA 2E94A 3NPRA 3N3DA 4DXJA 2F7MF 3ICKA 1N21A 3OABB 1N1BA 5C05A 2AZJA 4KVIA 3NPKA 3IPIA 4GAXA 5ILDA 1V4HA 3ZL6A 1V4IA 3VJEA 4DZWA 3KRFB 1FPSA 5B00A 4F62A 4DWBA 1KIYA 5HN9A 1HX9A 4LZ0A 4XQRF 3P41A 3LK5A 4E9ZA 3LLWA 4H5CF 3KRCB 5DIQF 2PS4A 2ZCSA 4LFVF 3ICZA 4NFIF 3TFPA 5JV2F 4KKMA 3VJ8A 3WCJA 4MC3A 3BNXA 5DGSF 1V4KA 3B7LA 3WEGA 2VF6A 2E95A 4LFEA 3WCCA 2F8ZF 1DGPA 3WCHA 3KB9A 3CP6A 3LJIA 2ZCOA 2E4OA 1YJ4A 3ADZA 3N1VF 5ILZA 1UBWA 5IMIA 3SDRA 3RMGA 2ONHA 3Q2ZA 5IL8A 2E8UA 3P8LA 3WCIA 3OACB 2H8OA 1VG3A 3LMDA 3MZVA 4KPJA 3PH7A 4E9UA 2Q58A 5IVGA 5IM1A 4P0XA 2F8CF 4PVYF 3VJBA 5B0IA 3KROA 5DW7A 5ILIA 3SDQA 1VG6A 3AQBB 3TFNA 3SDVA 3Q2QA 5JV0F 4K10A 3ZCDA 5AELA 4N9UA 1HXGA 4LPHF 3LG5A 3AQ0A 2OA6A 3TS7A 5HN7A 3N45F 5DJRF 4P0VA 3G4FA 4KQ5A 3EGTA 1KIZA 4LUUA 4JZXA 4OKZA 4NKFA 3ZMBA 3WJOA 5IKAA 3NF2A 2FORA 3AQCB 3VJCA 2OPMA 3KRPA 1VG4A 4KPDA 4XQSF 3LOMA 3CC9A 3AE0A 4KQUA 2E93A 3UCAA 1YYSA 3N0FA 4F6XA 1YHKA 1WMWA 3RYEA 3BNYA 1YHMA 3KRAA 2Q9ZA 3ICNA 3SDUA 3M00A 4OMGA 5AHUB 5JA0F 4NG6A 4GA3A 2Z4YA 3LGKA 3ZMCA 3WCLA 1N20A 1YHLA 1V4JA 5E8LA 2DH4A 5IKHA 1N1ZA 2I19A 3VJDA 2E8XA 3WCMA 4XQTF 4KFAA 2Z52A 3ICMA 4HD1A 5E8KA 2P1CA 5HNAA 5JV1F 3QKCA 5IMPA 2Z4WA 3P5PA 5B0JA 3APZA 5B0KA 4DHDA 2Z7HA 2ZEUA 4KK2A 5IK0A 5DHKA 1HXCA 4KWDA 5EATA 3WEHA 3N5JF 1UBYA 3Q1OA 4KQSA 2AELA 5A0KA 3M01A 3RYWA 1YQ7A 1PS1A 3LDWA 3OABA 3IBAA 4JVJF 3V66A 2F9KF 3ACXA 3WJNA 1HXAA 3WE9A 3WCAA 4LPGF 3N49F 4DEMF 5ERNA 3N0GA 1N23A 5JUZF 2Z4ZA 2Z4XA 5EROA 1DI1A 2J1OA 3WEKA 5B01A 1WL3A 1YV5A 1HM7A 3WCEA 1HM4A 1EZFA 3KRAB 4PVXF 4LA6A 2Q9YA 5DJVF 2E8WA 4QXSF 1WKZA 3DYFA 4ZQ8A 4GP1A 2PS6A 3N5HF 4WK5A 4EA1A 2ONGA 3V1VA 3WSAA 1UBXA 4LLTA 4RXAA 3SDTA 5HN8A 1UBVA 1WL2A 3SAEA 4JXNA 4NKEA 3TFVA 2J1PA 2O1OA 5DHIA 3ID0A 4H5DF 1JFGA 4LTZA 4JYXA 3PYAA 4EA0A 5ILHA 2F94F 4H5EF 2RAHA 4P0WA 5ERMA 5ILJA 2Q80A 1N24A 1VG7A 4LLSA 3QQVA 3LEEA 5DGMF 2E8VA 2PS5A 3M0GA 3MAVA 3KBKA 5DJPF 5B02A 1N22A 2E92A 1YYUA 1V4EA 3TC1A 3LZ9A 3N3LF 3DYHA 4KVYA 2PS7A 1WL1A 3WEIA 3P5RA 5A0IA 2OPNA 1WL0A 5AYPA 4JXYA 4DI5A 5B0LA 3Q30A 4RXCA 4RYPA 3S4JA 3WCGA 4QPFA 4RNQA 4LZ3A 5IMNA 4GP2A 3N1WF 2Z78A 2AEKA 2Z4VA 4LXWA 3CKEA 4OKMA 5B03A 4EA2A 3KROB 2AZLA 4LA5A 4LOBA 5ILKA 4DWGA 3M02A 5H9DA 5AFXA 5DZ2A 5IN8A 4JZBA 2FTZA 5ILYA 2F92F 3OYRA 3WC9A 3LGZB 2ZY1A 2AZKA 1JFAA 5IK9A 3WCDA 2E8TA 4OGUA 4F6VA 1YYTA 3LSNA 1RTRA 3S9VA 1RQJA 4NFJF 3M9UA 3DYGA 2ZCRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3N46 F;  3WEJ A;  3WSB A;  3ASX A;  3WCB A;  2Z50 A;  3KRP B;  3RBM A;  2E91 A;  5DGN F;  4KUX A;  3KRF A;  2ZEV A;  4NUA A;  2PS8 A;  3LVS A;  1WY0 A;  3V1X A;  3WJK A;  3PKO A;  3KRC A;  1VG2 A;  3WEF A;  4E1E A;  4MC0 A;  3W7F A;  4KVW A;  1YYQ A;  2Z7I A;  3G4D A;  4Q23 A;  3PYB A;  2OGD A;  4LZC A;  4LFG A;  1RQI A;  3VJ9 A;  4UMJ A;  4RXD A;  5E8H A;  2F89 F;  5IK6 A;  3VJA A;  4LTV A;  1YYR A;  4MC8 A;  3N6K F;  4L2X F;  5B0M A;  3EFQ A;  5ER8 A;  1ZW5 A;  5A0J A;  3ACY A;  2EWG A;  3OAC A;  3NRI A;  3EZ3 A;  5CG6 A;  4LIX A;  5KSX F;  5IL3 A;  3ZOU A;  3WCF A;  2AET A;  4N1Z F;  2J5C A;  5CG5 A;  4KVD A;  3PDE A;  4RXE A;  3P8R A;  5EAU A;  3ACW A;  2E90 A;  4NFK F;  4OMH A;  4FP4 A;  5I1U A;  4FJQ A;  5EAS A;  2ZCQ A;  2QIS A;  2E94 A;  3NPR A;  3N3D A;  4DXJ A;  2F7M F;  3ICK A;  1N21 A;  3OAB B;  1N1B A;  5C05 A;  2AZJ A;  4KVI A;  3NPK A;  3IPI A;  4GAX A;  5ILD A;  1V4H A;  3ZL6 A;  1V4I A;  3VJE A;  4DZW A;  3KRF B;  1FPS A;  5B00 A;  4F62 A;  4DWB A;  1KIY A;  5HN9 A;  1HX9 A;  4LZ0 A;  4XQR F;  3P41 A;  3LK5 A;  4E9Z A;  3LLW A;  4H5C F;  3KRC B;  5DIQ F;  2PS4 A;  2ZCS A;  4LFV F;  3ICZ A;  4NFI F;  3TFP A;  5JV2 F;  4KKM A;  3VJ8 A;  3WCJ A;  4MC3 A;  3BNX A;  5DGS F;  1V4K A;  3B7L A;  3WEG A;  2VF6 A;  2E95 A;  4LFE A;  3WCC A;  2F8Z F;  1DGP A;  3WCH A;  3KB9 A;  3CP6 A;  3LJI A;  2ZCO A;  2E4O A;  1YJ4 A;  3ADZ A;  3N1V F;  5ILZ A;  1UBW A;  5IMI A;  3SDR A;  3RMG A;  2ONH A;  3Q2Z A;  5IL8 A;  2E8U A;  3P8L A;  3WCI A;  3OAC B;  2H8O A;  1VG3 A;  3LMD A;  3MZV A;  4KPJ A;  3PH7 A;  4E9U A;  2Q58 A;  5IVG A;  5IM1 A;  4P0X A;  2F8C F;  4PVY F;  3VJB A;  5B0I A;  3KRO A;  5DW7 A;  5ILI A;  3SDQ A;  1VG6 A;  3AQB B;  3TFN A;  3SDV A;  3Q2Q A;  5JV0 F;  4K10 A;  3ZCD A;  5AEL A;  4N9U A;  1HXG A;  4LPH F;  3LG5 A;  3AQ0 A;  2OA6 A;  3TS7 A;  5HN7 A;  3N45 F;  5DJR F;  4P0V A;  3G4F A;  4KQ5 A;  3EGT A;  1KIZ A;  4LUU A;  4JZX A;  4OKZ A;  4NKF A;  3ZMB A;  3WJO A;  5IKA A;  3NF2 A;  2FOR A;  3AQC B;  3VJC A;  2OPM A;  3KRP A;  1VG4 A;  4KPD A;  4XQS F;  3LOM A;  3CC9 A;  3AE0 A;  4KQU A;  2E93 A;  3UCA A;  1YYS A;  3N0F A;  4F6X A;  1YHK A;  1WMW A;  3RYE A;  3BNY A;  1YHM A;  3KRA A;  2Q9Z A;  3ICN A;  3SDU A;  3M00 A;  4OMG A;  5AHU B;  5JA0 F;  4NG6 A;  4GA3 A;  2Z4Y A;  3LGK A;  3ZMC A;  3WCL A;  1N20 A;  1YHL A;  1V4J A;  5E8L A;  2DH4 A;  5IKH A;  1N1Z A;  2I19 A;  3VJD A;  2E8X A;  3WCM A;  4XQT F;  4KFA A;  2Z52 A;  3ICM A;  4HD1 A;  5E8K A;  2P1C A;  5HNA A;  5JV1 F;  3QKC A;  5IMP A;  2Z4W A;  3P5P A;  5B0J A;  3APZ A;  5B0K A;  4DHD A;  2Z7H A;  2ZEU A;  4KK2 A;  5IK0 A;  5DHK A;  1HXC A;  4KWD A;  5EAT A;  3WEH A;  3N5J F;  1UBY A;  3Q1O A;  4KQS A;  2AEL A;  5A0K A;  3M01 A;  3RYW A;  1YQ7 A;  1PS1 A;  3LDW A;  3OAB A;  3IBA A;  4JVJ F;  3V66 A;  2F9K F;  3ACX A;  3WJN A;  1HXA A;  3WE9 A;  3WCA A;  4LPG F;  3N49 F;  4DEM F;  5ERN A;  3N0G A;  1N23 A;  5JUZ F;  2Z4Z A;  2Z4X A;  5ERO A;  1DI1 A;  2J1O A;  3WEK A;  5B01 A;  1WL3 A;  1YV5 A;  1HM7 A;  3WCE A;  1HM4 A;  1EZF A;  3KRA B;  4PVX F;  4LA6 A;  2Q9Y A;  5DJV F;  2E8W A;  4QXS F;  1WKZ A;  3DYF A;  4ZQ8 A;  4GP1 A;  2PS6 A;  3N5H F;  4WK5 A;  4EA1 A;  2ONG A;  3V1V A;  3WSA A;  1UBX A;  4LLT A;  4RXA A;  3SDT A;  5HN8 A;  1UBV A;  1WL2 A;  3SAE A;  4JXN A;  4NKE A;  3TFV A;  2J1P A;  2O1O A;  5DHI A;  3ID0 A;  4H5D F;  1JFG A;  4LTZ A;  4JYX A;  3PYA A;  4EA0 A;  5ILH A;  2F94 F;  4H5E F;  2RAH A;  4P0W A;  5ERM A;  5ILJ A;  2Q80 A;  1N24 A;  1VG7 A;  4LLS A;  3QQV A;  3LEE A;  5DGM F;  2E8V A;  2PS5 A;  3M0G A;  3MAV A;  3KBK A;  5DJP F;  5B02 A;  1N22 A;  2E92 A;  1YYU A;  1V4E A;  3TC1 A;  3LZ9 A;  3N3L F;  3DYH A;  4KVY A;  2PS7 A;  1WL1 A;  3WEI A;  3P5R A;  5A0I A;  2OPN A;  1WL0 A;  5AYP A;  4JXY A;  4DI5 A;  5B0L A;  3Q30 A;  4RXC A;  4RYP A;  3S4J A;  3WCG A;  4QPF A;  4RNQ A;  4LZ3 A;  5IMN A;  4GP2 A;  3N1W F;  2Z78 A;  2AEK A;  2Z4V A;  4LXW A;  3CKE A;  4OKM A;  5B03 A;  4EA2 A;  3KRO B;  2AZL A;  4LA5 A;  4LOB A;  5ILK A;  4DWG A;  3M02 A;  5H9D A;  5AFX A;  5DZ2 A;  5IN8 A;  4JZB A;  2FTZ A;  5ILY A;  2F92 F;  3OYR A;  3WC9 A;  3LGZ B;  2ZY1 A;  2AZK A;  1JFA A;  5IK9 A;  3WCD A;  2E8T A;  4OGU A;  4F6V A;  1YYT A;  3LSN A;  1RTR A;  3S9V A;  1RQJ A;  4NFJ F;  3M9U A;  3DYG A;  2ZCR A; 
#chains in the Genus database with same CATH topology
 3N46 F;  3WEJ A;  3WSB A;  3ASX A;  3WCB A;  2Z50 A;  3KRP B;  3RBM A;  2E91 A;  5DGN F;  4KUX A;  3KRF A;  2ZEV A;  4NUA A;  2PS8 A;  3LVS A;  1WY0 A;  3V1X A;  3WJK A;  3PKO A;  3KRC A;  1VG2 A;  3WEF A;  4E1E A;  4MC0 A;  3W7F A;  4KVW A;  1YYQ A;  2Z7I A;  3G4D A;  4Q23 A;  3PYB A;  2OGD A;  4LZC A;  4LFG A;  1RQI A;  3VJ9 A;  4UMJ A;  4RXD A;  5E8H A;  2F89 F;  5IK6 A;  3VJA A;  4LTV A;  1YYR A;  4MC8 A;  3N6K F;  4L2X F;  5B0M A;  3EFQ A;  5ER8 A;  1ZW5 A;  5A0J A;  3ACY A;  2EWG A;  3OAC A;  3NRI A;  3EZ3 A;  5CG6 A;  4LIX A;  5KSX F;  5IL3 A;  3ZOU A;  3WCF A;  2AET A;  4N1Z F;  2J5C A;  5CG5 A;  4KVD A;  3PDE A;  4RXE A;  3P8R A;  5EAU A;  3ACW A;  2E90 A;  4NFK F;  4OMH A;  4FP4 A;  5I1U A;  4FJQ A;  5EAS A;  2ZCQ A;  2QIS A;  2E94 A;  3NPR A;  3N3D A;  4DXJ A;  2F7M F;  3ICK A;  1N21 A;  3OAB B;  1N1B A;  5C05 A;  2AZJ A;  4KVI A;  3NPK A;  3IPI A;  4GAX A;  5ILD A;  1V4H A;  3ZL6 A;  1V4I A;  3VJE A;  4DZW A;  3KRF B;  1FPS A;  5B00 A;  4F62 A;  4DWB A;  1KIY A;  5HN9 A;  1HX9 A;  4LZ0 A;  4XQR F;  3P41 A;  3LK5 A;  4E9Z A;  3LLW A;  4H5C F;  3KRC B;  5DIQ F;  2PS4 A;  2ZCS A;  4LFV F;  3ICZ A;  4NFI F;  3TFP A;  5JV2 F;  4KKM A;  3VJ8 A;  3WCJ A;  4MC3 A;  3BNX A;  5DGS F;  1V4K A;  3B7L A;  3WEG A;  2VF6 A;  2E95 A;  4LFE A;  3WCC A;  2F8Z F;  1DGP A;  3WCH A;  3KB9 A;  3CP6 A;  3LJI A;  2ZCO A;  2E4O A;  1YJ4 A;  3ADZ A;  3N1V F;  5ILZ A;  1UBW A;  5IMI A;  3SDR A;  3RMG A;  2ONH A;  3Q2Z A;  5IL8 A;  2E8U A;  3P8L A;  3WCI A;  3OAC B;  2H8O A;  1VG3 A;  3LMD A;  3MZV A;  4KPJ A;  3PH7 A;  4E9U A;  2Q58 A;  5IVG A;  5IM1 A;  4P0X A;  2F8C F;  4PVY F;  3VJB A;  5B0I A;  3KRO A;  5DW7 A;  5ILI A;  3SDQ A;  1VG6 A;  3AQB B;  3TFN A;  3SDV A;  3Q2Q A;  5JV0 F;  4K10 A;  3ZCD A;  5AEL A;  4N9U A;  1HXG A;  4LPH F;  3LG5 A;  3AQ0 A;  2OA6 A;  3TS7 A;  5HN7 A;  3N45 F;  5DJR F;  4P0V A;  3G4F A;  4KQ5 A;  3EGT A;  1KIZ A;  4LUU A;  4JZX A;  4OKZ A;  4NKF A;  3ZMB A;  3WJO A;  5IKA A;  3NF2 A;  2FOR A;  3AQC B;  3VJC A;  2OPM A;  3KRP A;  1VG4 A;  4KPD A;  4XQS F;  3LOM A;  3CC9 A;  3AE0 A;  4KQU A;  2E93 A;  3UCA A;  1YYS A;  3N0F A;  4F6X A;  1YHK A;  1WMW A;  3RYE A;  3BNY A;  1YHM A;  3KRA A;  2Q9Z A;  3ICN A;  3SDU A;  3M00 A;  4OMG A;  5AHU B;  5JA0 F;  4NG6 A;  4GA3 A;  2Z4Y A;  3LGK A;  3ZMC A;  3WCL A;  1N20 A;  1YHL A;  1V4J A;  5E8L A;  2DH4 A;  5IKH A;  1N1Z A;  2I19 A;  3VJD A;  2E8X A;  3WCM A;  4XQT F;  4KFA A;  2Z52 A;  3ICM A;  4HD1 A;  5E8K A;  2P1C A;  5HNA A;  5JV1 F;  3QKC A;  5IMP A;  2Z4W A;  3P5P A;  5B0J A;  3APZ A;  5B0K A;  4DHD A;  2Z7H A;  2ZEU A;  4KK2 A;  5IK0 A;  5DHK A;  1HXC A;  4KWD A;  5EAT A;  3WEH A;  3N5J F;  1UBY A;  3Q1O A;  4KQS A;  2AEL A;  5A0K A;  3M01 A;  3RYW A;  1YQ7 A;  1PS1 A;  3LDW A;  3OAB A;  3IBA A;  4JVJ F;  3V66 A;  2F9K F;  3ACX A;  3WJN A;  1HXA A;  3WE9 A;  3WCA A;  4LPG F;  3N49 F;  4DEM F;  5ERN A;  3N0G A;  1N23 A;  5JUZ F;  2Z4Z A;  2Z4X A;  5ERO A;  1DI1 A;  2J1O A;  3WEK A;  5B01 A;  1WL3 A;  1YV5 A;  1HM7 A;  3WCE A;  1HM4 A;  1EZF A;  3KRA B;  4PVX F;  4LA6 A;  2Q9Y A;  5DJV F;  2E8W A;  4QXS F;  1WKZ A;  3DYF A;  4ZQ8 A;  4GP1 A;  2PS6 A;  3N5H F;  4WK5 A;  4EA1 A;  2ONG A;  3V1V A;  3WSA A;  1UBX A;  4LLT A;  4RXA A;  3SDT A;  5HN8 A;  1UBV A;  1WL2 A;  3SAE A;  4JXN A;  4NKE A;  3TFV A;  2J1P A;  2O1O A;  5DHI A;  3ID0 A;  4H5D F;  1JFG A;  4LTZ A;  4JYX A;  3PYA A;  4EA0 A;  5ILH A;  2F94 F;  4H5E F;  2RAH A;  4P0W A;  5ERM A;  5ILJ A;  2Q80 A;  1N24 A;  1VG7 A;  4LLS A;  3QQV A;  3LEE A;  5DGM F;  2E8V A;  2PS5 A;  3M0G A;  3MAV A;  3KBK A;  5DJP F;  5B02 A;  1N22 A;  2E92 A;  1YYU A;  1V4E A;  3TC1 A;  3LZ9 A;  3N3L F;  3DYH A;  4KVY A;  2PS7 A;  1WL1 A;  3WEI A;  3P5R A;  5A0I A;  2OPN A;  1WL0 A;  5AYP A;  4JXY A;  4DI5 A;  5B0L A;  3Q30 A;  4RXC A;  4RYP A;  3S4J A;  3WCG A;  4QPF A;  4RNQ A;  4LZ3 A;  5IMN A;  4GP2 A;  3N1W F;  2Z78 A;  2AEK A;  2Z4V A;  4LXW A;  3CKE A;  4OKM A;  5B03 A;  4EA2 A;  3KRO B;  2AZL A;  4LA5 A;  4LOB A;  5ILK A;  4DWG A;  3M02 A;  5H9D A;  5AFX A;  5DZ2 A;  5IN8 A;  4JZB A;  2FTZ A;  5ILY A;  2F92 F;  3OYR A;  3WC9 A;  3LGZ B;  2ZY1 A;  2AZK A;  1JFA A;  5IK9 A;  3WCD A;  2E8T A;  4OGU A;  4F6V A;  1YYT A;  3LSN A;  1RTR A;  3S9V A;  1RQJ A;  4NFJ F;  3M9U A;  3DYG A;  2ZCR A; 
#chains in the Genus database with same CATH homology
 3N46 F;  3WEJ A;  3WSB A;  3ASX A;  3WCB A;  2Z50 A;  3KRP B;  3RBM A;  2E91 A;  5DGN F;  4KUX A;  3KRF A;  2ZEV A;  4NUA A;  2PS8 A;  3LVS A;  1WY0 A;  3V1X A;  3WJK A;  3PKO A;  3KRC A;  1VG2 A;  3WEF A;  4E1E A;  4MC0 A;  3W7F A;  4KVW A;  1YYQ A;  2Z7I A;  3G4D A;  4Q23 A;  3PYB A;  2OGD A;  4LZC A;  4LFG A;  1RQI A;  3VJ9 A;  4UMJ A;  4RXD A;  5E8H A;  2F89 F;  5IK6 A;  3VJA A;  4LTV A;  1YYR A;  4MC8 A;  3N6K F;  4L2X F;  5B0M A;  3EFQ A;  5ER8 A;  1ZW5 A;  5A0J A;  3ACY A;  2EWG A;  3OAC A;  3NRI A;  3EZ3 A;  5CG6 A;  4LIX A;  5KSX F;  5IL3 A;  3ZOU A;  3WCF A;  2AET A;  4N1Z F;  2J5C A;  5CG5 A;  4KVD A;  3PDE A;  4RXE A;  3P8R A;  5EAU A;  3ACW A;  2E90 A;  4NFK F;  4OMH A;  4FP4 A;  5I1U A;  4FJQ A;  5EAS A;  2ZCQ A;  2QIS A;  2E94 A;  3NPR A;  3N3D A;  4DXJ A;  2F7M F;  3ICK A;  1N21 A;  3OAB B;  1N1B A;  5C05 A;  2AZJ A;  4KVI A;  3NPK A;  3IPI A;  4GAX A;  5ILD A;  1V4H A;  3ZL6 A;  1V4I A;  3VJE A;  4DZW A;  3KRF B;  1FPS A;  5B00 A;  4F62 A;  4DWB A;  1KIY A;  5HN9 A;  1HX9 A;  4LZ0 A;  4XQR F;  3P41 A;  3LK5 A;  4E9Z A;  3LLW A;  4H5C F;  3KRC B;  5DIQ F;  2PS4 A;  2ZCS A;  4LFV F;  3ICZ A;  4NFI F;  3TFP A;  5JV2 F;  4KKM A;  3VJ8 A;  3WCJ A;  4MC3 A;  3BNX A;  5DGS F;  1V4K A;  3B7L A;  3WEG A;  2VF6 A;  2E95 A;  4LFE A;  3WCC A;  2F8Z F;  1DGP A;  3WCH A;  3KB9 A;  3CP6 A;  3LJI A;  2ZCO A;  2E4O A;  1YJ4 A;  3ADZ A;  3N1V F;  5ILZ A;  1UBW A;  5IMI A;  3SDR A;  3RMG A;  2ONH A;  3Q2Z A;  5IL8 A;  2E8U A;  3P8L A;  3WCI A;  3OAC B;  2H8O A;  1VG3 A;  3LMD A;  3MZV A;  4KPJ A;  3PH7 A;  4E9U A;  2Q58 A;  5IVG A;  5IM1 A;  4P0X A;  2F8C F;  4PVY F;  3VJB A;  5B0I A;  3KRO A;  5DW7 A;  5ILI A;  3SDQ A;  1VG6 A;  3AQB B;  3TFN A;  3SDV A;  3Q2Q A;  5JV0 F;  4K10 A;  3ZCD A;  5AEL A;  4N9U A;  1HXG A;  4LPH F;  3LG5 A;  3AQ0 A;  2OA6 A;  3TS7 A;  5HN7 A;  3N45 F;  5DJR F;  4P0V A;  3G4F A;  4KQ5 A;  3EGT A;  1KIZ A;  4LUU A;  4JZX A;  4OKZ A;  4NKF A;  3ZMB A;  3WJO A;  5IKA A;  3NF2 A;  2FOR A;  3AQC B;  3VJC A;  2OPM A;  3KRP A;  1VG4 A;  4KPD A;  4XQS F;  3LOM A;  3CC9 A;  3AE0 A;  4KQU A;  2E93 A;  3UCA A;  1YYS A;  3N0F A;  4F6X A;  1YHK A;  1WMW A;  3RYE A;  3BNY A;  1YHM A;  3KRA A;  2Q9Z A;  3ICN A;  3SDU A;  3M00 A;  4OMG A;  5AHU B;  5JA0 F;  4NG6 A;  4GA3 A;  2Z4Y A;  3LGK A;  3ZMC A;  3WCL A;  1N20 A;  1YHL A;  1V4J A;  5E8L A;  2DH4 A;  5IKH A;  1N1Z A;  2I19 A;  3VJD A;  2E8X A;  3WCM A;  4XQT F;  4KFA A;  2Z52 A;  3ICM A;  4HD1 A;  5E8K A;  2P1C A;  5HNA A;  5JV1 F;  3QKC A;  5IMP A;  2Z4W A;  3P5P A;  5B0J A;  3APZ A;  5B0K A;  4DHD A;  2Z7H A;  2ZEU A;  4KK2 A;  5IK0 A;  5DHK A;  1HXC A;  4KWD A;  5EAT A;  3WEH A;  3N5J F;  1UBY A;  3Q1O A;  4KQS A;  2AEL A;  5A0K A;  3M01 A;  3RYW A;  1YQ7 A;  1PS1 A;  3LDW A;  3OAB A;  3IBA A;  4JVJ F;  3V66 A;  2F9K F;  3ACX A;  3WJN A;  1HXA A;  3WE9 A;  3WCA A;  4LPG F;  3N49 F;  4DEM F;  5ERN A;  3N0G A;  1N23 A;  5JUZ F;  2Z4Z A;  2Z4X A;  5ERO A;  1DI1 A;  2J1O A;  3WEK A;  5B01 A;  1WL3 A;  1YV5 A;  1HM7 A;  3WCE A;  1HM4 A;  1EZF A;  3KRA B;  4PVX F;  4LA6 A;  2Q9Y A;  5DJV F;  2E8W A;  4QXS F;  1WKZ A;  3DYF A;  4ZQ8 A;  4GP1 A;  2PS6 A;  3N5H F;  4WK5 A;  4EA1 A;  2ONG A;  3V1V A;  3WSA A;  1UBX A;  4LLT A;  4RXA A;  3SDT A;  5HN8 A;  1UBV A;  1WL2 A;  3SAE A;  4JXN A;  4NKE A;  3TFV A;  2J1P A;  2O1O A;  5DHI A;  3ID0 A;  4H5D F;  1JFG A;  4LTZ A;  4JYX A;  3PYA A;  4EA0 A;  5ILH A;  2F94 F;  4H5E F;  2RAH A;  4P0W A;  5ERM A;  5ILJ A;  2Q80 A;  1N24 A;  1VG7 A;  4LLS A;  3QQV A;  3LEE A;  5DGM F;  2E8V A;  2PS5 A;  3M0G A;  3MAV A;  3KBK A;  5DJP F;  5B02 A;  1N22 A;  2E92 A;  1YYU A;  1V4E A;  3TC1 A;  3LZ9 A;  3N3L F;  3DYH A;  4KVY A;  2PS7 A;  1WL1 A;  3WEI A;  3P5R A;  5A0I A;  2OPN A;  1WL0 A;  5AYP A;  4JXY A;  4DI5 A;  5B0L A;  3Q30 A;  4RXC A;  4RYP A;  3S4J A;  3WCG A;  4QPF A;  4RNQ A;  4LZ3 A;  5IMN A;  4GP2 A;  3N1W F;  2Z78 A;  2AEK A;  2Z4V A;  4LXW A;  3CKE A;  4OKM A;  5B03 A;  4EA2 A;  3KRO B;  2AZL A;  4LA5 A;  4LOB A;  5ILK A;  4DWG A;  3M02 A;  5H9D A;  5AFX A;  5DZ2 A;  5IN8 A;  4JZB A;  2FTZ A;  5ILY A;  2F92 F;  3OYR A;  3WC9 A;  3LGZ B;  2ZY1 A;  2AZK A;  1JFA A;  5IK9 A;  3WCD A;  2E8T A;  4OGU A;  4F6V A;  1YYT A;  3LSN A;  1RTR A;  3S9V A;  1RQJ A;  4NFJ F;  3M9U A;  3DYG A;  2ZCR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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