1RQJA

Active conformation of farnesyl pyrophosphate synthase bound to isopentyl pyrophosphate and risedronate
Total Genus 126
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
126
sequence length
299
structure length
299
Chain Sequence
MDFPQQLEACVKQANQALSRFIAPLPFQNTPVVETMQYGALLGGKRLRPFLVYATGHMFGVSTNTLDAPAAAVECIHAYSLIHDDLPAMDDDDLRRGLPTCHVKFGEANAILAGDALQTLAFSILSDADMPEVSDRDRISMISELASASGIAGMCGGQALDLDAEGKHVPLDALERIHRHKTGALIRAAVRLGALSAGDKGRRALPVLDKYAESIGLAFQVQDDILDVVGDTATLGKRQGADQQLGKSTYPALLGLEQARKKARDLIDDARQSLKQLAEQSLDTSALEALADYIIQRNK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for bisphosphonate-mediated inhibition of isoprenoid biosynthesis
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords Geranyltranstransferase
total genus 126
structure length 299
sequence length 299
chains with identical sequence B
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2003-12-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 1rqjA00
3WC9A 2F89F 4GP1A 3CC9A 3Q2QA 1YHKA 2Z78A 5IKAA 2Z52A 2PS7A 2E93A 2F92F 5KSXF 1N1ZA 3G4DA 5EASA 5ERMA 3VJ8A 3SDTA 3WJOA 2F7MF 1N1BA 4JXYA 2ONHA 3DYHA 4PVXF 1YYTA 4DHDA 5IL3A 4MC8A 3BNYA 4LUUA 5JV2F 2EWGA 2Z4ZA 1V4KA 4LFEA 3WCHA 1YYUA 4XQRF 2AZLA 3ICZA 4EA1A 2ZEVA 1UBVA 3KB9A 3KRCB 5IK0A 3RYEA 4PVYF 3ACXA 3N45F 3WEJA 2E91A 1WL1A 2F8CF 3SDRA 3TC1A 2F8ZF 4OMGA 5AHUB 3ZCDA 5C05A 1YYSA 2I19A 1V4JA 5ILYA 2Z4XA 5JV1F 4EA0A 1UBYA 4DZWA 3KRCA 2PS4A 5DJVF 3CKEA 5DHKA 2RAHA 2O1OA 3PDEA 4RYPA 3ZMCA 3MZVA 4NFJF 3ACYA 3APZA 3LGKA 5ILIA 3P8RA 3P5RA 3TS7A 2E4OA 5E8LA 5EROA 3CP6A 4OGUA 1WL3A 3EZ3A 2ZEUA 4EA2A 2F9KF 3LG5A 3N5JF 4KPDA 5B0KA 2AELA 3VJEA 4P0WA 3WCDA 1YYQA 4GA3A 4N9UA 5DJPF 3WCEA 4JZBA 1WMWA 3NPRA 4LXWA 5IMPA 4F6VA 1N21A 4JYXA 4LFGA 3NPKA 3SDQA 2PS8A 4NUAA 5E8KA 1UBXA 3WSBA 1HXAA 4UMJA 5AELA 1YHMA 4DXJA 1RTRA 3WCIA 2E92A 1RQIA 3RMGA 4KVWA 4NG6A 5IK9A 4KVIA 2J1OA 3N3LF 4E9ZA 4XQTF 2E95A 4KPJA 2E8TA 3V1XA 2ZCSA 2Z50A 3LVSA 4OKMA 4JVJF 2OPMA 2P1CA 1VG4A 3VJAA 3N49F 3TFVA 3ZMBA 3N5HF 5AFXA 3KRAB 4FP4A 3WEKA 2DH4A 3PYAA 4KQ5A 4NKEA 4LOBA 4OKZA 4KK2A 1N24A 4F62A 4RXDA 3BNXA 5B01A 3B7LA 3ICKA 3LGZB 3TFPA 1DI1A 5B02A 3LMDA 5B0LA 4LPGF 3VJBA 5CG6A 2Z4VA 4LA5A 4WK5A 2ONGA 2AZJA 5HNAA 3KBKA 3KRAA 3WE9A 5B0MA 4GAXA 5AYPA 3V66A 4KUXA 2Z7IA 4P0XA 3KROA 2ZY1A 3N6KF 2J5CA 1PS1A 3AE0A 5ILDA 1N22A 2H8OA 3N3DA 3LOMA 5CG5A 4P0VA 4DI5A 5ILHA 4KWDA 2Q58A 1V4HA 4JXNA 5IMIA 2E8UA 3WEGA 3IBAA 1YJ4A 3M0GA 3LJIA 3N46F 5DJRF 1N23A 4E1EA 3LK5A 3AQCB 1JFAA 4NFKF 4MC0A 5IVGA 4KVYA 2PS5A 2F94F 2FTZA 3IPIA 5DGNF 4DEMF 3LDWA 3ICNA 3LLWA 2E90A 3QQVA 4QPFA 4RNQA 3P5PA 3V1VA 2OGDA 1VG7A 2ZCRA 5DW7A 3OACA 3NF2A 5IKHA 1VG3A 4LTVA 3VJ9A 4N1ZF 2Q9ZA 3OABB 5IM1A 2Q80A 2Z4YA 1WY0A 5DIQF 2PS6A 5ERNA 1YV5A 1YHLA 4RXAA 4ZQ8A 2E8XA 1RQJA 2QISA 3M02A 4LA6A 3OABA 4K10A 5B0JA 5DGMF 5ILJA 3ZOUA 3G4FA 5IL8A 3WCBA 3EGTA 3WCAA 4LIXA 3ADZA 4E9UA 3LSNA 4LZ3A 5DGSF 3RYWA 1HX9A 5HN9A 4LPHF 3SDVA 1JFGA 1ZW5A 3OYRA 3WCJA 5ILKA 5E8HA 3RBMA 5JV0F 3ZL6A 3ICMA 5B03A 3S4JA 3DYGA 3KROB 1FPSA 3PH7A 3PYBA 5A0IA 4LLSA 4RXCA 1KIZA 4L2XF 3NRIA 4QXSF 1WL2A 3LEEA 4LFVF 3KRPA 5EATA 5HN7A 5EAUA 4DWBA 2E94A 3N1WF 3WEIA 1WKZA 3Q30A 3ASXA 5B00A 4KQSA 4RXEA 3WCLA 3P41A 1VG6A 4HD1A 5B0IA 4F6XA 1HXCA 1V4EA 5A0KA 2OA6A 5ER8A 1V4IA 1DGPA 5JA0F 4DWGA 3WEFA 2J1PA 3N0FA 4MC3A 2VF6A 5H9DA 4NKFA 3SDUA 3OACB 3LZ9A 3AQBB 4LZCA 1WL0A 5ILZA 4OMHA 3P8LA 4NFIF 3VJDA 3VJCA 2AETA 3ID0A 2E8VA 3KRFB 4LLTA 1YYRA 2AZKA 5DZ2A 1UBWA 4H5DF 4KKMA 2ZCOA 1VG2A 4LTZA 3N1VF 3Q1OA 1EZFA 1N20A 5DHIA 2AEKA 4XQSF 3WJNA 3M00A 3N0GA 3WEHA 5JUZF 3Q2ZA 4KQUA 5IK6A 4H5CF 4JZXA 3UCAA 3SAEA 3KRFA 4KVDA 3WCFA 3M9UA 1HM7A 1YQ7A 2Z4WA 4GP2A 4LZ0A 2E8WA 1HXGA 3WSAA 3PKOA 2Z7HA 3WJKA 5IMNA 1HM4A 3M01A 5IN8A 5A0JA 4H5EF 3DYFA 4Q23A 4FJQA 3ACWA 3WCMA 5I1UA 2OPNA 3TFNA 3WCGA 1KIYA 3QKCA 3W7FA 4KFAA 2Q9YA 3MAVA 3S9VA 5HN8A 3WCCA 2ZCQA 3AQ0A 3KRPB 3EFQA 2FORA
chains in the Genus database with same CATH superfamily
3WC9A 2F89F 4GP1A 3CC9A 3Q2QA 1YHKA 2Z78A 5IKAA 2Z52A 2PS7A 2E93A 2F92F 5KSXF 1N1ZA 3G4DA 5EASA 5ERMA 3VJ8A 3SDTA 3WJOA 2F7MF 1N1BA 4JXYA 2ONHA 3DYHA 4PVXF 1YYTA 4DHDA 5IL3A 4MC8A 3BNYA 4LUUA 5JV2F 2EWGA 2Z4ZA 1V4KA 4LFEA 3WCHA 1YYUA 4XQRF 2AZLA 3ICZA 4EA1A 2ZEVA 1UBVA 3KB9A 3KRCB 5IK0A 3RYEA 4PVYF 3ACXA 3N45F 3WEJA 2E91A 1WL1A 2F8CF 3SDRA 3TC1A 2F8ZF 4OMGA 5AHUB 3ZCDA 5C05A 1YYSA 2I19A 1V4JA 5ILYA 2Z4XA 5JV1F 4EA0A 1UBYA 4DZWA 3KRCA 2PS4A 5DJVF 3CKEA 5DHKA 2RAHA 2O1OA 3PDEA 4RYPA 3ZMCA 3MZVA 4NFJF 3ACYA 3APZA 3LGKA 5ILIA 3P8RA 3P5RA 3TS7A 2E4OA 5E8LA 5EROA 3CP6A 4OGUA 1WL3A 3EZ3A 2ZEUA 4EA2A 2F9KF 3LG5A 3N5JF 4KPDA 5B0KA 2AELA 3VJEA 4P0WA 3WCDA 1YYQA 4GA3A 4N9UA 5DJPF 3WCEA 4JZBA 1WMWA 3NPRA 4LXWA 5IMPA 4F6VA 1N21A 4JYXA 4LFGA 3NPKA 3SDQA 2PS8A 4NUAA 5E8KA 1UBXA 3WSBA 1HXAA 4UMJA 5AELA 1YHMA 4DXJA 1RTRA 3WCIA 2E92A 1RQIA 3RMGA 4KVWA 4NG6A 5IK9A 4KVIA 2J1OA 3N3LF 4E9ZA 4XQTF 2E95A 4KPJA 2E8TA 3V1XA 2ZCSA 2Z50A 3LVSA 4OKMA 4JVJF 2OPMA 2P1CA 1VG4A 3VJAA 3N49F 3TFVA 3ZMBA 3N5HF 5AFXA 3KRAB 4FP4A 3WEKA 2DH4A 3PYAA 4KQ5A 4NKEA 4LOBA 4OKZA 4KK2A 1N24A 4F62A 4RXDA 3BNXA 5B01A 3B7LA 3ICKA 3LGZB 3TFPA 1DI1A 5B02A 3LMDA 5B0LA 4LPGF 3VJBA 5CG6A 2Z4VA 4LA5A 4WK5A 2ONGA 2AZJA 5HNAA 3KBKA 3KRAA 3WE9A 5B0MA 4GAXA 5AYPA 3V66A 4KUXA 2Z7IA 4P0XA 3KROA 2ZY1A 3N6KF 2J5CA 1PS1A 3AE0A 5ILDA 1N22A 2H8OA 3N3DA 3LOMA 5CG5A 4P0VA 4DI5A 5ILHA 4KWDA 2Q58A 1V4HA 4JXNA 5IMIA 2E8UA 3WEGA 3IBAA 1YJ4A 3M0GA 3LJIA 3N46F 5DJRF 1N23A 4E1EA 3LK5A 3AQCB 1JFAA 4NFKF 4MC0A 5IVGA 4KVYA 2PS5A 2F94F 2FTZA 3IPIA 5DGNF 4DEMF 3LDWA 3ICNA 3LLWA 2E90A 3QQVA 4QPFA 4RNQA 3P5PA 3V1VA 2OGDA 1VG7A 2ZCRA 5DW7A 3OACA 3NF2A 5IKHA 1VG3A 4LTVA 3VJ9A 4N1ZF 2Q9ZA 3OABB 5IM1A 2Q80A 2Z4YA 1WY0A 5DIQF 2PS6A 5ERNA 1YV5A 1YHLA 4RXAA 4ZQ8A 2E8XA 1RQJA 2QISA 3M02A 4LA6A 3OABA 4K10A 5B0JA 5DGMF 5ILJA 3ZOUA 3G4FA 5IL8A 3WCBA 3EGTA 3WCAA 4LIXA 3ADZA 4E9UA 3LSNA 4LZ3A 5DGSF 3RYWA 1HX9A 5HN9A 4LPHF 3SDVA 1JFGA 1ZW5A 3OYRA 3WCJA 5ILKA 5E8HA 3RBMA 5JV0F 3ZL6A 3ICMA 5B03A 3S4JA 3DYGA 3KROB 1FPSA 3PH7A 3PYBA 5A0IA 4LLSA 4RXCA 1KIZA 4L2XF 3NRIA 4QXSF 1WL2A 3LEEA 4LFVF 3KRPA 5EATA 5HN7A 5EAUA 4DWBA 2E94A 3N1WF 3WEIA 1WKZA 3Q30A 3ASXA 5B00A 4KQSA 4RXEA 3WCLA 3P41A 1VG6A 4HD1A 5B0IA 4F6XA 1HXCA 1V4EA 5A0KA 2OA6A 5ER8A 1V4IA 1DGPA 5JA0F 4DWGA 3WEFA 2J1PA 3N0FA 4MC3A 2VF6A 5H9DA 4NKFA 3SDUA 3OACB 3LZ9A 3AQBB 4LZCA 1WL0A 5ILZA 4OMHA 3P8LA 4NFIF 3VJDA 3VJCA 2AETA 3ID0A 2E8VA 3KRFB 4LLTA 1YYRA 2AZKA 5DZ2A 1UBWA 4H5DF 4KKMA 2ZCOA 1VG2A 4LTZA 3N1VF 3Q1OA 1EZFA 1N20A 5DHIA 2AEKA 4XQSF 3WJNA 3M00A 3N0GA 3WEHA 5JUZF 3Q2ZA 4KQUA 5IK6A 4H5CF 4JZXA 3UCAA 3SAEA 3KRFA 4KVDA 3WCFA 3M9UA 1HM7A 1YQ7A 2Z4WA 4GP2A 4LZ0A 2E8WA 1HXGA 3WSAA 3PKOA 2Z7HA 3WJKA 5IMNA 1HM4A 3M01A 5IN8A 5A0JA 4H5EF 3DYFA 4Q23A 4FJQA 3ACWA 3WCMA 5I1UA 2OPNA 3TFNA 3WCGA 1KIYA 3QKCA 3W7FA 4KFAA 2Q9YA 3MAVA 3S9VA 5HN8A 3WCCA 2ZCQA 3AQ0A 3KRPB 3EFQA 2FORA
chains in the Genus database with same CATH topology
3WC9A 2F89F 4GP1A 3CC9A 3Q2QA 1YHKA 2Z78A 5IKAA 2Z52A 2PS7A 2E93A 2F92F 5KSXF 1N1ZA 3G4DA 5EASA 5ERMA 3VJ8A 3SDTA 3WJOA 2F7MF 1N1BA 4JXYA 2ONHA 3DYHA 4PVXF 1YYTA 4DHDA 5IL3A 4MC8A 3BNYA 4LUUA 5JV2F 2EWGA 2Z4ZA 1V4KA 4LFEA 3WCHA 1YYUA 4XQRF 2AZLA 3ICZA 4EA1A 2ZEVA 1UBVA 3KB9A 3KRCB 5IK0A 3RYEA 4PVYF 3ACXA 3N45F 3WEJA 2E91A 1WL1A 2F8CF 3SDRA 3TC1A 2F8ZF 4OMGA 5AHUB 3ZCDA 5C05A 1YYSA 2I19A 1V4JA 5ILYA 2Z4XA 5JV1F 4EA0A 1UBYA 4DZWA 3KRCA 2PS4A 5DJVF 3CKEA 5DHKA 2RAHA 2O1OA 3PDEA 4RYPA 3ZMCA 3MZVA 4NFJF 3ACYA 3APZA 3LGKA 5ILIA 3P8RA 3P5RA 3TS7A 2E4OA 5E8LA 5EROA 3CP6A 4OGUA 1WL3A 3EZ3A 2ZEUA 4EA2A 2F9KF 3LG5A 3N5JF 4KPDA 5B0KA 2AELA 3VJEA 4P0WA 3WCDA 1YYQA 4GA3A 4N9UA 5DJPF 3WCEA 4JZBA 1WMWA 3NPRA 4LXWA 5IMPA 4F6VA 1N21A 4JYXA 4LFGA 3NPKA 3SDQA 2PS8A 4NUAA 5E8KA 1UBXA 3WSBA 1HXAA 4UMJA 5AELA 1YHMA 4DXJA 1RTRA 3WCIA 2E92A 1RQIA 3RMGA 4KVWA 4NG6A 5IK9A 4KVIA 2J1OA 3N3LF 4E9ZA 4XQTF 2E95A 4KPJA 2E8TA 3V1XA 2ZCSA 2Z50A 3LVSA 4OKMA 4JVJF 2OPMA 2P1CA 1VG4A 3VJAA 3N49F 3TFVA 3ZMBA 3N5HF 5AFXA 3KRAB 4FP4A 3WEKA 2DH4A 3PYAA 4KQ5A 4NKEA 4LOBA 4OKZA 4KK2A 1N24A 4F62A 4RXDA 3BNXA 5B01A 3B7LA 3ICKA 3LGZB 3TFPA 1DI1A 5B02A 3LMDA 5B0LA 4LPGF 3VJBA 5CG6A 2Z4VA 4LA5A 4WK5A 2ONGA 2AZJA 5HNAA 3KBKA 3KRAA 3WE9A 5B0MA 4GAXA 5AYPA 3V66A 4KUXA 2Z7IA 4P0XA 3KROA 2ZY1A 3N6KF 2J5CA 1PS1A 3AE0A 5ILDA 1N22A 2H8OA 3N3DA 3LOMA 5CG5A 4P0VA 4DI5A 5ILHA 4KWDA 2Q58A 1V4HA 4JXNA 5IMIA 2E8UA 3WEGA 3IBAA 1YJ4A 3M0GA 3LJIA 3N46F 5DJRF 1N23A 4E1EA 3LK5A 3AQCB 1JFAA 4NFKF 4MC0A 5IVGA 4KVYA 2PS5A 2F94F 2FTZA 3IPIA 5DGNF 4DEMF 3LDWA 3ICNA 3LLWA 2E90A 3QQVA 4QPFA 4RNQA 3P5PA 3V1VA 2OGDA 1VG7A 2ZCRA 5DW7A 3OACA 3NF2A 5IKHA 1VG3A 4LTVA 3VJ9A 4N1ZF 2Q9ZA 3OABB 5IM1A 2Q80A 2Z4YA 1WY0A 5DIQF 2PS6A 5ERNA 1YV5A 1YHLA 4RXAA 4ZQ8A 2E8XA 1RQJA 2QISA 3M02A 4LA6A 3OABA 4K10A 5B0JA 5DGMF 5ILJA 3ZOUA 3G4FA 5IL8A 3WCBA 3EGTA 3WCAA 4LIXA 3ADZA 4E9UA 3LSNA 4LZ3A 5DGSF 3RYWA 1HX9A 5HN9A 4LPHF 3SDVA 1JFGA 1ZW5A 3OYRA 3WCJA 5ILKA 5E8HA 3RBMA 5JV0F 3ZL6A 3ICMA 5B03A 3S4JA 3DYGA 3KROB 1FPSA 3PH7A 3PYBA 5A0IA 4LLSA 4RXCA 1KIZA 4L2XF 3NRIA 4QXSF 1WL2A 3LEEA 4LFVF 3KRPA 5EATA 5HN7A 5EAUA 4DWBA 2E94A 3N1WF 3WEIA 1WKZA 3Q30A 3ASXA 5B00A 4KQSA 4RXEA 3WCLA 3P41A 1VG6A 4HD1A 5B0IA 4F6XA 1HXCA 1V4EA 5A0KA 2OA6A 5ER8A 1V4IA 1DGPA 5JA0F 4DWGA 3WEFA 2J1PA 3N0FA 4MC3A 2VF6A 5H9DA 4NKFA 3SDUA 3OACB 3LZ9A 3AQBB 4LZCA 1WL0A 5ILZA 4OMHA 3P8LA 4NFIF 3VJDA 3VJCA 2AETA 3ID0A 2E8VA 3KRFB 4LLTA 1YYRA 2AZKA 5DZ2A 1UBWA 4H5DF 4KKMA 2ZCOA 1VG2A 4LTZA 3N1VF 3Q1OA 1EZFA 1N20A 5DHIA 2AEKA 4XQSF 3WJNA 3M00A 3N0GA 3WEHA 5JUZF 3Q2ZA 4KQUA 5IK6A 4H5CF 4JZXA 3UCAA 3SAEA 3KRFA 4KVDA 3WCFA 3M9UA 1HM7A 1YQ7A 2Z4WA 4GP2A 4LZ0A 2E8WA 1HXGA 3WSAA 3PKOA 2Z7HA 3WJKA 5IMNA 1HM4A 3M01A 5IN8A 5A0JA 4H5EF 3DYFA 4Q23A 4FJQA 3ACWA 3WCMA 5I1UA 2OPNA 3TFNA 3WCGA 1KIYA 3QKCA 3W7FA 4KFAA 2Q9YA 3MAVA 3S9VA 5HN8A 3WCCA 2ZCQA 3AQ0A 3KRPB 3EFQA 2FORA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3WC9 A;  2F89 F;  4GP1 A;  3CC9 A;  3Q2Q A;  1YHK A;  2Z78 A;  5IKA A;  2Z52 A;  2PS7 A;  2E93 A;  2F92 F;  5KSX F;  1N1Z A;  3G4D A;  5EAS A;  5ERM A;  3VJ8 A;  3SDT A;  3WJO A;  2F7M F;  1N1B A;  4JXY A;  2ONH A;  3DYH A;  4PVX F;  1YYT A;  4DHD A;  5IL3 A;  4MC8 A;  3BNY A;  4LUU A;  5JV2 F;  2EWG A;  2Z4Z A;  1V4K A;  4LFE A;  3WCH A;  1YYU A;  4XQR F;  2AZL A;  3ICZ A;  4EA1 A;  2ZEV A;  1UBV A;  3KB9 A;  3KRC B;  5IK0 A;  3RYE A;  4PVY F;  3ACX A;  3N45 F;  3WEJ A;  2E91 A;  1WL1 A;  2F8C F;  3SDR A;  3TC1 A;  2F8Z F;  4OMG A;  5AHU B;  3ZCD A;  5C05 A;  1YYS A;  2I19 A;  1V4J A;  5ILY A;  2Z4X A;  5JV1 F;  4EA0 A;  1UBY A;  4DZW A;  3KRC A;  2PS4 A;  5DJV F;  3CKE A;  5DHK A;  2RAH A;  2O1O A;  3PDE A;  4RYP A;  3ZMC A;  3MZV A;  4NFJ F;  3ACY A;  3APZ A;  3LGK A;  5ILI A;  3P8R A;  3P5R A;  3TS7 A;  2E4O A;  5E8L A;  5ERO A;  3CP6 A;  4OGU A;  1WL3 A;  3EZ3 A;  2ZEU A;  4EA2 A;  2F9K F;  3LG5 A;  3N5J F;  4KPD A;  5B0K A;  2AEL A;  3VJE A;  4P0W A;  3WCD A;  1YYQ A;  4GA3 A;  4N9U A;  5DJP F;  3WCE A;  4JZB A;  1WMW A;  3NPR A;  4LXW A;  5IMP A;  4F6V A;  1N21 A;  4JYX A;  4LFG A;  3NPK A;  3SDQ A;  2PS8 A;  4NUA A;  5E8K A;  1UBX A;  3WSB A;  1HXA A;  4UMJ A;  5AEL A;  1YHM A;  4DXJ A;  1RTR A;  3WCI A;  2E92 A;  1RQI A;  3RMG A;  4KVW A;  4NG6 A;  5IK9 A;  4KVI A;  2J1O A;  3N3L F;  4E9Z A;  4XQT F;  2E95 A;  4KPJ A;  2E8T A;  3V1X A;  2ZCS A;  2Z50 A;  3LVS A;  4OKM A;  4JVJ F;  2OPM A;  2P1C A;  1VG4 A;  3VJA A;  3N49 F;  3TFV A;  3ZMB A;  3N5H F;  5AFX A;  3KRA B;  4FP4 A;  3WEK A;  2DH4 A;  3PYA A;  4KQ5 A;  4NKE A;  4LOB A;  4OKZ A;  4KK2 A;  1N24 A;  4F62 A;  4RXD A;  3BNX A;  5B01 A;  3B7L A;  3ICK A;  3LGZ B;  3TFP A;  1DI1 A;  5B02 A;  3LMD A;  5B0L A;  4LPG F;  3VJB A;  5CG6 A;  2Z4V A;  4LA5 A;  4WK5 A;  2ONG A;  2AZJ A;  5HNA A;  3KBK A;  3KRA A;  3WE9 A;  5B0M A;  4GAX A;  5AYP A;  3V66 A;  4KUX A;  2Z7I A;  4P0X A;  3KRO A;  2ZY1 A;  3N6K F;  2J5C A;  1PS1 A;  3AE0 A;  5ILD A;  1N22 A;  2H8O A;  3N3D A;  3LOM A;  5CG5 A;  4P0V A;  4DI5 A;  5ILH A;  4KWD A;  2Q58 A;  1V4H A;  4JXN A;  5IMI A;  2E8U A;  3WEG A;  3IBA A;  1YJ4 A;  3M0G A;  3LJI A;  3N46 F;  5DJR F;  1N23 A;  4E1E A;  3LK5 A;  3AQC B;  1JFA A;  4NFK F;  4MC0 A;  5IVG A;  4KVY A;  2PS5 A;  2F94 F;  2FTZ A;  3IPI A;  5DGN F;  4DEM F;  3LDW A;  3ICN A;  3LLW A;  2E90 A;  3QQV A;  4QPF A;  4RNQ A;  3P5P A;  3V1V A;  2OGD A;  1VG7 A;  2ZCR A;  5DW7 A;  3OAC A;  3NF2 A;  5IKH A;  1VG3 A;  4LTV A;  3VJ9 A;  4N1Z F;  2Q9Z A;  3OAB B;  5IM1 A;  2Q80 A;  2Z4Y A;  1WY0 A;  5DIQ F;  2PS6 A;  5ERN A;  1YV5 A;  1YHL A;  4RXA A;  4ZQ8 A;  2E8X A;  1RQJ A;  2QIS A;  3M02 A;  4LA6 A;  3OAB A;  4K10 A;  5B0J A;  5DGM F;  5ILJ A;  3ZOU A;  3G4F A;  5IL8 A;  3WCB A;  3EGT A;  3WCA A;  4LIX A;  3ADZ A;  4E9U A;  3LSN A;  4LZ3 A;  5DGS F;  3RYW A;  1HX9 A;  5HN9 A;  4LPH F;  3SDV A;  1JFG A;  1ZW5 A;  3OYR A;  3WCJ A;  5ILK A;  5E8H A;  3RBM A;  5JV0 F;  3ZL6 A;  3ICM A;  5B03 A;  3S4J A;  3DYG A;  3KRO B;  1FPS A;  3PH7 A;  3PYB A;  5A0I A;  4LLS A;  4RXC A;  1KIZ A;  4L2X F;  3NRI A;  4QXS F;  1WL2 A;  3LEE A;  4LFV F;  3KRP A;  5EAT A;  5HN7 A;  5EAU A;  4DWB A;  2E94 A;  3N1W F;  3WEI A;  1WKZ A;  3Q30 A;  3ASX A;  5B00 A;  4KQS A;  4RXE A;  3WCL A;  3P41 A;  1VG6 A;  4HD1 A;  5B0I A;  4F6X A;  1HXC A;  1V4E A;  5A0K A;  2OA6 A;  5ER8 A;  1V4I A;  1DGP A;  5JA0 F;  4DWG A;  3WEF A;  2J1P A;  3N0F A;  4MC3 A;  2VF6 A;  5H9D A;  4NKF A;  3SDU A;  3OAC B;  3LZ9 A;  3AQB B;  4LZC A;  1WL0 A;  5ILZ A;  4OMH A;  3P8L A;  4NFI F;  3VJD A;  3VJC A;  2AET A;  3ID0 A;  2E8V A;  3KRF B;  4LLT A;  1YYR A;  2AZK A;  5DZ2 A;  1UBW A;  4H5D F;  4KKM A;  2ZCO A;  1VG2 A;  4LTZ A;  3N1V F;  3Q1O A;  1EZF A;  1N20 A;  5DHI A;  2AEK A;  4XQS F;  3WJN A;  3M00 A;  3N0G A;  3WEH A;  5JUZ F;  3Q2Z A;  4KQU A;  5IK6 A;  4H5C F;  4JZX A;  3UCA A;  3SAE A;  3KRF A;  4KVD A;  3WCF A;  3M9U A;  1HM7 A;  1YQ7 A;  2Z4W A;  4GP2 A;  4LZ0 A;  2E8W A;  1HXG A;  3WSA A;  3PKO A;  2Z7H A;  3WJK A;  5IMN A;  1HM4 A;  3M01 A;  5IN8 A;  5A0J A;  4H5E F;  3DYF A;  4Q23 A;  4FJQ A;  3ACW A;  3WCM A;  5I1U A;  2OPN A;  3TFN A;  3WCG A;  1KIY A;  3QKC A;  3W7F A;  4KFA A;  2Q9Y A;  3MAV A;  3S9V A;  5HN8 A;  3WCC A;  2ZCQ A;  3AQ0 A;  3KRP B;  3EFQ A;  2FOR A; 
#chains in the Genus database with same CATH topology
 3WC9 A;  2F89 F;  4GP1 A;  3CC9 A;  3Q2Q A;  1YHK A;  2Z78 A;  5IKA A;  2Z52 A;  2PS7 A;  2E93 A;  2F92 F;  5KSX F;  1N1Z A;  3G4D A;  5EAS A;  5ERM A;  3VJ8 A;  3SDT A;  3WJO A;  2F7M F;  1N1B A;  4JXY A;  2ONH A;  3DYH A;  4PVX F;  1YYT A;  4DHD A;  5IL3 A;  4MC8 A;  3BNY A;  4LUU A;  5JV2 F;  2EWG A;  2Z4Z A;  1V4K A;  4LFE A;  3WCH A;  1YYU A;  4XQR F;  2AZL A;  3ICZ A;  4EA1 A;  2ZEV A;  1UBV A;  3KB9 A;  3KRC B;  5IK0 A;  3RYE A;  4PVY F;  3ACX A;  3N45 F;  3WEJ A;  2E91 A;  1WL1 A;  2F8C F;  3SDR A;  3TC1 A;  2F8Z F;  4OMG A;  5AHU B;  3ZCD A;  5C05 A;  1YYS A;  2I19 A;  1V4J A;  5ILY A;  2Z4X A;  5JV1 F;  4EA0 A;  1UBY A;  4DZW A;  3KRC A;  2PS4 A;  5DJV F;  3CKE A;  5DHK A;  2RAH A;  2O1O A;  3PDE A;  4RYP A;  3ZMC A;  3MZV A;  4NFJ F;  3ACY A;  3APZ A;  3LGK A;  5ILI A;  3P8R A;  3P5R A;  3TS7 A;  2E4O A;  5E8L A;  5ERO A;  3CP6 A;  4OGU A;  1WL3 A;  3EZ3 A;  2ZEU A;  4EA2 A;  2F9K F;  3LG5 A;  3N5J F;  4KPD A;  5B0K A;  2AEL A;  3VJE A;  4P0W A;  3WCD A;  1YYQ A;  4GA3 A;  4N9U A;  5DJP F;  3WCE A;  4JZB A;  1WMW A;  3NPR A;  4LXW A;  5IMP A;  4F6V A;  1N21 A;  4JYX A;  4LFG A;  3NPK A;  3SDQ A;  2PS8 A;  4NUA A;  5E8K A;  1UBX A;  3WSB A;  1HXA A;  4UMJ A;  5AEL A;  1YHM A;  4DXJ A;  1RTR A;  3WCI A;  2E92 A;  1RQI A;  3RMG A;  4KVW A;  4NG6 A;  5IK9 A;  4KVI A;  2J1O A;  3N3L F;  4E9Z A;  4XQT F;  2E95 A;  4KPJ A;  2E8T A;  3V1X A;  2ZCS A;  2Z50 A;  3LVS A;  4OKM A;  4JVJ F;  2OPM A;  2P1C A;  1VG4 A;  3VJA A;  3N49 F;  3TFV A;  3ZMB A;  3N5H F;  5AFX A;  3KRA B;  4FP4 A;  3WEK A;  2DH4 A;  3PYA A;  4KQ5 A;  4NKE A;  4LOB A;  4OKZ A;  4KK2 A;  1N24 A;  4F62 A;  4RXD A;  3BNX A;  5B01 A;  3B7L A;  3ICK A;  3LGZ B;  3TFP A;  1DI1 A;  5B02 A;  3LMD A;  5B0L A;  4LPG F;  3VJB A;  5CG6 A;  2Z4V A;  4LA5 A;  4WK5 A;  2ONG A;  2AZJ A;  5HNA A;  3KBK A;  3KRA A;  3WE9 A;  5B0M A;  4GAX A;  5AYP A;  3V66 A;  4KUX A;  2Z7I A;  4P0X A;  3KRO A;  2ZY1 A;  3N6K F;  2J5C A;  1PS1 A;  3AE0 A;  5ILD A;  1N22 A;  2H8O A;  3N3D A;  3LOM A;  5CG5 A;  4P0V A;  4DI5 A;  5ILH A;  4KWD A;  2Q58 A;  1V4H A;  4JXN A;  5IMI A;  2E8U A;  3WEG A;  3IBA A;  1YJ4 A;  3M0G A;  3LJI A;  3N46 F;  5DJR F;  1N23 A;  4E1E A;  3LK5 A;  3AQC B;  1JFA A;  4NFK F;  4MC0 A;  5IVG A;  4KVY A;  2PS5 A;  2F94 F;  2FTZ A;  3IPI A;  5DGN F;  4DEM F;  3LDW A;  3ICN A;  3LLW A;  2E90 A;  3QQV A;  4QPF A;  4RNQ A;  3P5P A;  3V1V A;  2OGD A;  1VG7 A;  2ZCR A;  5DW7 A;  3OAC A;  3NF2 A;  5IKH A;  1VG3 A;  4LTV A;  3VJ9 A;  4N1Z F;  2Q9Z A;  3OAB B;  5IM1 A;  2Q80 A;  2Z4Y A;  1WY0 A;  5DIQ F;  2PS6 A;  5ERN A;  1YV5 A;  1YHL A;  4RXA A;  4ZQ8 A;  2E8X A;  1RQJ A;  2QIS A;  3M02 A;  4LA6 A;  3OAB A;  4K10 A;  5B0J A;  5DGM F;  5ILJ A;  3ZOU A;  3G4F A;  5IL8 A;  3WCB A;  3EGT A;  3WCA A;  4LIX A;  3ADZ A;  4E9U A;  3LSN A;  4LZ3 A;  5DGS F;  3RYW A;  1HX9 A;  5HN9 A;  4LPH F;  3SDV A;  1JFG A;  1ZW5 A;  3OYR A;  3WCJ A;  5ILK A;  5E8H A;  3RBM A;  5JV0 F;  3ZL6 A;  3ICM A;  5B03 A;  3S4J A;  3DYG A;  3KRO B;  1FPS A;  3PH7 A;  3PYB A;  5A0I A;  4LLS A;  4RXC A;  1KIZ A;  4L2X F;  3NRI A;  4QXS F;  1WL2 A;  3LEE A;  4LFV F;  3KRP A;  5EAT A;  5HN7 A;  5EAU A;  4DWB A;  2E94 A;  3N1W F;  3WEI A;  1WKZ A;  3Q30 A;  3ASX A;  5B00 A;  4KQS A;  4RXE A;  3WCL A;  3P41 A;  1VG6 A;  4HD1 A;  5B0I A;  4F6X A;  1HXC A;  1V4E A;  5A0K A;  2OA6 A;  5ER8 A;  1V4I A;  1DGP A;  5JA0 F;  4DWG A;  3WEF A;  2J1P A;  3N0F A;  4MC3 A;  2VF6 A;  5H9D A;  4NKF A;  3SDU A;  3OAC B;  3LZ9 A;  3AQB B;  4LZC A;  1WL0 A;  5ILZ A;  4OMH A;  3P8L A;  4NFI F;  3VJD A;  3VJC A;  2AET A;  3ID0 A;  2E8V A;  3KRF B;  4LLT A;  1YYR A;  2AZK A;  5DZ2 A;  1UBW A;  4H5D F;  4KKM A;  2ZCO A;  1VG2 A;  4LTZ A;  3N1V F;  3Q1O A;  1EZF A;  1N20 A;  5DHI A;  2AEK A;  4XQS F;  3WJN A;  3M00 A;  3N0G A;  3WEH A;  5JUZ F;  3Q2Z A;  4KQU A;  5IK6 A;  4H5C F;  4JZX A;  3UCA A;  3SAE A;  3KRF A;  4KVD A;  3WCF A;  3M9U A;  1HM7 A;  1YQ7 A;  2Z4W A;  4GP2 A;  4LZ0 A;  2E8W A;  1HXG A;  3WSA A;  3PKO A;  2Z7H A;  3WJK A;  5IMN A;  1HM4 A;  3M01 A;  5IN8 A;  5A0J A;  4H5E F;  3DYF A;  4Q23 A;  4FJQ A;  3ACW A;  3WCM A;  5I1U A;  2OPN A;  3TFN A;  3WCG A;  1KIY A;  3QKC A;  3W7F A;  4KFA A;  2Q9Y A;  3MAV A;  3S9V A;  5HN8 A;  3WCC A;  2ZCQ A;  3AQ0 A;  3KRP B;  3EFQ A;  2FOR A; 
#chains in the Genus database with same CATH homology
 3WC9 A;  2F89 F;  4GP1 A;  3CC9 A;  3Q2Q A;  1YHK A;  2Z78 A;  5IKA A;  2Z52 A;  2PS7 A;  2E93 A;  2F92 F;  5KSX F;  1N1Z A;  3G4D A;  5EAS A;  5ERM A;  3VJ8 A;  3SDT A;  3WJO A;  2F7M F;  1N1B A;  4JXY A;  2ONH A;  3DYH A;  4PVX F;  1YYT A;  4DHD A;  5IL3 A;  4MC8 A;  3BNY A;  4LUU A;  5JV2 F;  2EWG A;  2Z4Z A;  1V4K A;  4LFE A;  3WCH A;  1YYU A;  4XQR F;  2AZL A;  3ICZ A;  4EA1 A;  2ZEV A;  1UBV A;  3KB9 A;  3KRC B;  5IK0 A;  3RYE A;  4PVY F;  3ACX A;  3N45 F;  3WEJ A;  2E91 A;  1WL1 A;  2F8C F;  3SDR A;  3TC1 A;  2F8Z F;  4OMG A;  5AHU B;  3ZCD A;  5C05 A;  1YYS A;  2I19 A;  1V4J A;  5ILY A;  2Z4X A;  5JV1 F;  4EA0 A;  1UBY A;  4DZW A;  3KRC A;  2PS4 A;  5DJV F;  3CKE A;  5DHK A;  2RAH A;  2O1O A;  3PDE A;  4RYP A;  3ZMC A;  3MZV A;  4NFJ F;  3ACY A;  3APZ A;  3LGK A;  5ILI A;  3P8R A;  3P5R A;  3TS7 A;  2E4O A;  5E8L A;  5ERO A;  3CP6 A;  4OGU A;  1WL3 A;  3EZ3 A;  2ZEU A;  4EA2 A;  2F9K F;  3LG5 A;  3N5J F;  4KPD A;  5B0K A;  2AEL A;  3VJE A;  4P0W A;  3WCD A;  1YYQ A;  4GA3 A;  4N9U A;  5DJP F;  3WCE A;  4JZB A;  1WMW A;  3NPR A;  4LXW A;  5IMP A;  4F6V A;  1N21 A;  4JYX A;  4LFG A;  3NPK A;  3SDQ A;  2PS8 A;  4NUA A;  5E8K A;  1UBX A;  3WSB A;  1HXA A;  4UMJ A;  5AEL A;  1YHM A;  4DXJ A;  1RTR A;  3WCI A;  2E92 A;  1RQI A;  3RMG A;  4KVW A;  4NG6 A;  5IK9 A;  4KVI A;  2J1O A;  3N3L F;  4E9Z A;  4XQT F;  2E95 A;  4KPJ A;  2E8T A;  3V1X A;  2ZCS A;  2Z50 A;  3LVS A;  4OKM A;  4JVJ F;  2OPM A;  2P1C A;  1VG4 A;  3VJA A;  3N49 F;  3TFV A;  3ZMB A;  3N5H F;  5AFX A;  3KRA B;  4FP4 A;  3WEK A;  2DH4 A;  3PYA A;  4KQ5 A;  4NKE A;  4LOB A;  4OKZ A;  4KK2 A;  1N24 A;  4F62 A;  4RXD A;  3BNX A;  5B01 A;  3B7L A;  3ICK A;  3LGZ B;  3TFP A;  1DI1 A;  5B02 A;  3LMD A;  5B0L A;  4LPG F;  3VJB A;  5CG6 A;  2Z4V A;  4LA5 A;  4WK5 A;  2ONG A;  2AZJ A;  5HNA A;  3KBK A;  3KRA A;  3WE9 A;  5B0M A;  4GAX A;  5AYP A;  3V66 A;  4KUX A;  2Z7I A;  4P0X A;  3KRO A;  2ZY1 A;  3N6K F;  2J5C A;  1PS1 A;  3AE0 A;  5ILD A;  1N22 A;  2H8O A;  3N3D A;  3LOM A;  5CG5 A;  4P0V A;  4DI5 A;  5ILH A;  4KWD A;  2Q58 A;  1V4H A;  4JXN A;  5IMI A;  2E8U A;  3WEG A;  3IBA A;  1YJ4 A;  3M0G A;  3LJI A;  3N46 F;  5DJR F;  1N23 A;  4E1E A;  3LK5 A;  3AQC B;  1JFA A;  4NFK F;  4MC0 A;  5IVG A;  4KVY A;  2PS5 A;  2F94 F;  2FTZ A;  3IPI A;  5DGN F;  4DEM F;  3LDW A;  3ICN A;  3LLW A;  2E90 A;  3QQV A;  4QPF A;  4RNQ A;  3P5P A;  3V1V A;  2OGD A;  1VG7 A;  2ZCR A;  5DW7 A;  3OAC A;  3NF2 A;  5IKH A;  1VG3 A;  4LTV A;  3VJ9 A;  4N1Z F;  2Q9Z A;  3OAB B;  5IM1 A;  2Q80 A;  2Z4Y A;  1WY0 A;  5DIQ F;  2PS6 A;  5ERN A;  1YV5 A;  1YHL A;  4RXA A;  4ZQ8 A;  2E8X A;  1RQJ A;  2QIS A;  3M02 A;  4LA6 A;  3OAB A;  4K10 A;  5B0J A;  5DGM F;  5ILJ A;  3ZOU A;  3G4F A;  5IL8 A;  3WCB A;  3EGT A;  3WCA A;  4LIX A;  3ADZ A;  4E9U A;  3LSN A;  4LZ3 A;  5DGS F;  3RYW A;  1HX9 A;  5HN9 A;  4LPH F;  3SDV A;  1JFG A;  1ZW5 A;  3OYR A;  3WCJ A;  5ILK A;  5E8H A;  3RBM A;  5JV0 F;  3ZL6 A;  3ICM A;  5B03 A;  3S4J A;  3DYG A;  3KRO B;  1FPS A;  3PH7 A;  3PYB A;  5A0I A;  4LLS A;  4RXC A;  1KIZ A;  4L2X F;  3NRI A;  4QXS F;  1WL2 A;  3LEE A;  4LFV F;  3KRP A;  5EAT A;  5HN7 A;  5EAU A;  4DWB A;  2E94 A;  3N1W F;  3WEI A;  1WKZ A;  3Q30 A;  3ASX A;  5B00 A;  4KQS A;  4RXE A;  3WCL A;  3P41 A;  1VG6 A;  4HD1 A;  5B0I A;  4F6X A;  1HXC A;  1V4E A;  5A0K A;  2OA6 A;  5ER8 A;  1V4I A;  1DGP A;  5JA0 F;  4DWG A;  3WEF A;  2J1P A;  3N0F A;  4MC3 A;  2VF6 A;  5H9D A;  4NKF A;  3SDU A;  3OAC B;  3LZ9 A;  3AQB B;  4LZC A;  1WL0 A;  5ILZ A;  4OMH A;  3P8L A;  4NFI F;  3VJD A;  3VJC A;  2AET A;  3ID0 A;  2E8V A;  3KRF B;  4LLT A;  1YYR A;  2AZK A;  5DZ2 A;  1UBW A;  4H5D F;  4KKM A;  2ZCO A;  1VG2 A;  4LTZ A;  3N1V F;  3Q1O A;  1EZF A;  1N20 A;  5DHI A;  2AEK A;  4XQS F;  3WJN A;  3M00 A;  3N0G A;  3WEH A;  5JUZ F;  3Q2Z A;  4KQU A;  5IK6 A;  4H5C F;  4JZX A;  3UCA A;  3SAE A;  3KRF A;  4KVD A;  3WCF A;  3M9U A;  1HM7 A;  1YQ7 A;  2Z4W A;  4GP2 A;  4LZ0 A;  2E8W A;  1HXG A;  3WSA A;  3PKO A;  2Z7H A;  3WJK A;  5IMN A;  1HM4 A;  3M01 A;  5IN8 A;  5A0J A;  4H5E F;  3DYF A;  4Q23 A;  4FJQ A;  3ACW A;  3WCM A;  5I1U A;  2OPN A;  3TFN A;  3WCG A;  1KIY A;  3QKC A;  3W7F A;  4KFA A;  2Q9Y A;  3MAV A;  3S9V A;  5HN8 A;  3WCC A;  2ZCQ A;  3AQ0 A;  3KRP B;  3EFQ A;  2FOR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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