4K10A

Crystal structure of leshmaniasis major farnesyl diphosphate synthase in complex with 3-fluoro-1-(2-hydroxy-2,2-diphosphonoethyl)pyridinium and mg2+
Total Genus 146
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
146
sequence length
361
structure length
358
Chain Sequence
MAHMERFQKVYEEVQEFLLGDAEKRFEMDVHRKGYLKSMMDTTCLGGKYNRGLCVVDVAEAMAKDTQMDAAAMERVLHDACVCGWMIEMLQAHFLVEDDIMDHSKTRRGKPCWYLHPGVTAQVAINDGLILLAWATQMALHYFADRPFLAEVLRVFHDVDLTTTIGQLYDVTSMVDSAKLDAKVAHANTTDYVEYTPFNHRRIVVYKTAYYTYWLPLVMGLLVSGTLEKVDKKATHKVAMVMGEYFQVQDDVMDCFTPPEKIGTDIEDAKCSWLAVTFLTTAPAEKVAEFKANYGSTDPAAVAVIKQLYTEQNLLARFEEYEKAVVAEVEQLIAALEAQNAAFAASVKVLWSKTYKRQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Structural and thermodynamic basis of the inhibition of Leishmania major farnesyl diphosphate synthase by nitrogen-containing bisphosphonates.
pubmed doi rcsb
molecule keywords Farnesyl pyrophosphate synthase
molecule tags Transferase/transferase inhibitor
source organism Leishmania major
total genus 146
structure length 358
sequence length 361
chains with identical sequence B, C, D
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2013-04-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4k10A00
3W7FA 5IVGA 5ILIA 1ZW5A 4E9UA 3LK5A 3TFVA 1DGPA 5JV1F 2O1OA 3KRCB 4OKZA 4E9ZA 5DW7A 2F8CF 4NG6A 1N24A 2ZCSA 1VG4A 5EROA 2PS5A 2Z4YA 2PS6A 5IN8A 3TC1A 4KPDA 2ZCRA 3WEHA 3PDEA 3WCAA 3WEIA 3M0GA 3SDQA 3Q2ZA 4LLTA 3TFNA 2OGDA 4KQ5A 2E8TA 4P0XA 4F6VA 2AETA 3MAVA 5HN8A 2RAHA 1N1ZA 3N3DA 3SAEA 2Q58A 5EATA 3AQ0A 5B02A 3N46F 3ICMA 1N21A 3EZ3A 5DHKA 4KKMA 1V4JA 3WEJA 3WC9A 1UBWA 2E8UA 1YV5A 3QQVA 3VJDA 4EA0A 1WKZA 4NKEA 1V4KA 4EA2A 4KVWA 3WCBA 3Q1OA 5ILJA 3KBKA 2Z7HA 3SDRA 3ZMCA 3B7LA 3WCJA 2ZY1A 1UBXA 4LUUA 4NFIF 5CG5A 1FPSA 1VG3A 4KK2A 2E94A 1HXGA 3WJKA 5ERNA 3WCIA 1V4IA 3RMGA 4HD1A 1YYRA 2E8WA 4LFGA 5JA0F 3KB9A 3OACB 3WCGA 1KIYA 4DWBA 2ONGA 3V66A 5EASA 2Z50A 4DI5A 3N0GA 4MC8A 2PS4A 5DZ2A 5IMIA 3ICZA 3M02A 4GP2A 1YJ4A 4OKMA 3WSAA 3KRPA 5IK6A 3WCHA 4GAXA 3KRFA 4ZQ8A 5ILHA 5AELA 5A0KA 4RNQA 3OABB 5B0KA 1UBVA 3KRPB 2E90A 4KUXA 2FTZA 4KWDA 2J1OA 5AHUB 3KRFB 4JVJF 5AYPA 2E4OA 1RQIA 5E8LA 3ICNA 4JXNA 4LA5A 5DGNF 4JZXA 4KQSA 3LSNA 2EWGA 3DYGA 4K10A 3TFPA 5B0IA 3P8LA 5DGMF 5HNAA 5IMPA 1VG7A 5I1UA 3S4JA 2OPNA 5ILZA 3ID0A 3CKEA 3LZ9A 3WCMA 4RYPA 2F9KF 3WEGA 3BNYA 5E8HA 3LJIA 3NF2A 4N9UA 3SDVA 4F62A 5H9DA 4F6XA 5IL3A 4LZ3A 1KIZA 2J5CA 5C05A 1JFGA 4LZ0A 4DHDA 2ZCQA 3AQCB 4NUAA 3SDUA 4QXSF 3TS7A 4N1ZF 3PYBA 5B0MA 2AZLA 3ACXA 1YHMA 2Z4WA 4LFVF 4DWGA 4PVYF 3VJCA 4LA6A 3RYWA 4DXJA 1WY0A 3WE9A 1WL0A 4PVXF 2Z4ZA 4GA3A 3WCCA 2ZEVA 4KPJA 4UMJA 4P0VA 3LGKA 4KVIA 4OGUA 2DH4A 3P5RA 2AZJA 2OA6A 4GP1A 2Z78A 3N3LF 1HX9A 3EFQA 3Q2QA 2F94F 1N23A 3AQBB 3NPKA 4XQRF 4JZBA 5A0JA 4LLSA 1YHKA 3P41A 1WL1A 4RXDA 5B0LA 3ZMBA 2OPMA 3V1VA 4KFAA 4H5CF 5IK0A 2E8VA 3SDTA 4RXAA 4E1EA 3NRIA 1YYTA 3IBAA 2Z4VA 5IMNA 2P1CA 4H5DF 2F92F 5E8KA 3V1XA 3PYAA 2E92A 1VG2A 2VF6A 3KRAA 3QKCA 2E91A 3G4DA 3LVSA 4LZCA 5ILKA 3KRAB 5JUZF 2AZKA 2AEKA 2QISA 3KROA 3WSBA 5DIQF 5B03A 4LXWA 4P0WA 3CP6A 3RBMA 1N20A 3EGTA 2H8OA 1WL2A 3LMDA 5IKAA 4FJQA 5AFXA 4QPFA 1WL3A 3N49F 4KVYA 5DJPF 5EAUA 4NFJF 2E95A 3N1WF 4LFEA 4XQSF 5CG6A 2Q80A 3M01A 3KRCA 3PKOA 3WJOA 4WK5A 3WJNA 3WCLA 3VJAA 4L2XF 5B00A 1JFAA 1V4HA 2Z4XA 4LIXA 5B0JA 3WCEA 3ICKA 1V4EA 3MZVA 3IPIA 5ILDA 4EA1A 4JYXA 1EZFA 2PS8A 3OYRA 5DJVF 4DZWA 2ZCOA 5IK9A 2FORA 4RXEA 4XQTF 4MC3A 1N22A 4KVDA 3CC9A 4NKFA 3ACYA 4FP4A 3AE0A 3LG5A 3ZOUA 4OMGA 1HXAA 5KSXF 2I19A 3UCAA 3ZCDA 3M00A 1RTRA 3LEEA 5IKHA 1YYQA 3DYHA 1PS1A 1WMWA 3WCDA 5DHIA 3N0FA 1YYUA 3BNXA 3DYFA 2Q9ZA 2Z7IA 3WEKA 2F7MF 3NPRA 1VG6A 3Q30A 4RXCA 3ZL6A 1HM4A 2Z52A 2Q9YA 3LGZB 2PS7A 1N1BA 4DEMF 5IM1A 4Q23A 3G4FA 1DI1A 1UBYA 3ASXA 3LDWA 3LLWA 3WCFA 3LOMA 1YQ7A 3N5HF 5ER8A 3PH7A 2F8ZF 5ILYA 5IL8A 1YYSA 1YHLA 3OACA 2E93A 3P5PA 3S9VA 5DJRF 5ERMA 4MC0A 4LOBA 3VJ8A 2J1PA 2E8XA 2F89F 2AELA 4JXYA 3VJEA 3M9UA 4NFKF 4LPGF 3APZA 3WEFA 3KROB 5A0IA 3VJBA 5HN9A 3RYEA 1RQJA 5JV2F 3N6KF 1HM7A 5DGSF 3OABA 2ZEUA 4KQUA 3N5JF 5B01A 3N1VF 1HXCA 4H5EF 3ADZA 3N45F 3VJ9A 5JV0F 3P8RA 4OMHA 4LTVA 2ONHA 4LPHF 4LTZA 5HN7A 3ACWA
chains in the Genus database with same CATH superfamily
3W7FA 5IVGA 5ILIA 1ZW5A 4E9UA 3LK5A 3TFVA 1DGPA 5JV1F 2O1OA 3KRCB 4OKZA 4E9ZA 5DW7A 2F8CF 4NG6A 1N24A 2ZCSA 1VG4A 5EROA 2PS5A 2Z4YA 2PS6A 5IN8A 3TC1A 4KPDA 2ZCRA 3WEHA 3PDEA 3WCAA 3WEIA 3M0GA 3SDQA 3Q2ZA 4LLTA 3TFNA 2OGDA 4KQ5A 2E8TA 4P0XA 4F6VA 2AETA 3MAVA 5HN8A 2RAHA 1N1ZA 3N3DA 3SAEA 2Q58A 5EATA 3AQ0A 5B02A 3N46F 3ICMA 1N21A 3EZ3A 5DHKA 4KKMA 1V4JA 3WEJA 3WC9A 1UBWA 2E8UA 1YV5A 3QQVA 3VJDA 4EA0A 1WKZA 4NKEA 1V4KA 4EA2A 4KVWA 3WCBA 3Q1OA 5ILJA 3KBKA 2Z7HA 3SDRA 3ZMCA 3B7LA 3WCJA 2ZY1A 1UBXA 4LUUA 4NFIF 5CG5A 1FPSA 1VG3A 4KK2A 2E94A 1HXGA 3WJKA 5ERNA 3WCIA 1V4IA 3RMGA 4HD1A 1YYRA 2E8WA 4LFGA 5JA0F 3KB9A 3OACB 3WCGA 1KIYA 4DWBA 2ONGA 3V66A 5EASA 2Z50A 4DI5A 3N0GA 4MC8A 2PS4A 5DZ2A 5IMIA 3ICZA 3M02A 4GP2A 1YJ4A 4OKMA 3WSAA 3KRPA 5IK6A 3WCHA 4GAXA 3KRFA 4ZQ8A 5ILHA 5AELA 5A0KA 4RNQA 3OABB 5B0KA 1UBVA 3KRPB 2E90A 4KUXA 2FTZA 4KWDA 2J1OA 5AHUB 3KRFB 4JVJF 5AYPA 2E4OA 1RQIA 5E8LA 3ICNA 4JXNA 4LA5A 5DGNF 4JZXA 4KQSA 3LSNA 2EWGA 3DYGA 4K10A 3TFPA 5B0IA 3P8LA 5DGMF 5HNAA 5IMPA 1VG7A 5I1UA 3S4JA 2OPNA 5ILZA 3ID0A 3CKEA 3LZ9A 3WCMA 4RYPA 2F9KF 3WEGA 3BNYA 5E8HA 3LJIA 3NF2A 4N9UA 3SDVA 4F62A 5H9DA 4F6XA 5IL3A 4LZ3A 1KIZA 2J5CA 5C05A 1JFGA 4LZ0A 4DHDA 2ZCQA 3AQCB 4NUAA 3SDUA 4QXSF 3TS7A 4N1ZF 3PYBA 5B0MA 2AZLA 3ACXA 1YHMA 2Z4WA 4LFVF 4DWGA 4PVYF 3VJCA 4LA6A 3RYWA 4DXJA 1WY0A 3WE9A 1WL0A 4PVXF 2Z4ZA 4GA3A 3WCCA 2ZEVA 4KPJA 4UMJA 4P0VA 3LGKA 4KVIA 4OGUA 2DH4A 3P5RA 2AZJA 2OA6A 4GP1A 2Z78A 3N3LF 1HX9A 3EFQA 3Q2QA 2F94F 1N23A 3AQBB 3NPKA 4XQRF 4JZBA 5A0JA 4LLSA 1YHKA 3P41A 1WL1A 4RXDA 5B0LA 3ZMBA 2OPMA 3V1VA 4KFAA 4H5CF 5IK0A 2E8VA 3SDTA 4RXAA 4E1EA 3NRIA 1YYTA 3IBAA 2Z4VA 5IMNA 2P1CA 4H5DF 2F92F 5E8KA 3V1XA 3PYAA 2E92A 1VG2A 2VF6A 3KRAA 3QKCA 2E91A 3G4DA 3LVSA 4LZCA 5ILKA 3KRAB 5JUZF 2AZKA 2AEKA 2QISA 3KROA 3WSBA 5DIQF 5B03A 4LXWA 4P0WA 3CP6A 3RBMA 1N20A 3EGTA 2H8OA 1WL2A 3LMDA 5IKAA 4FJQA 5AFXA 4QPFA 1WL3A 3N49F 4KVYA 5DJPF 5EAUA 4NFJF 2E95A 3N1WF 4LFEA 4XQSF 5CG6A 2Q80A 3M01A 3KRCA 3PKOA 3WJOA 4WK5A 3WJNA 3WCLA 3VJAA 4L2XF 5B00A 1JFAA 1V4HA 2Z4XA 4LIXA 5B0JA 3WCEA 3ICKA 1V4EA 3MZVA 3IPIA 5ILDA 4EA1A 4JYXA 1EZFA 2PS8A 3OYRA 5DJVF 4DZWA 2ZCOA 5IK9A 2FORA 4RXEA 4XQTF 4MC3A 1N22A 4KVDA 3CC9A 4NKFA 3ACYA 4FP4A 3AE0A 3LG5A 3ZOUA 4OMGA 1HXAA 5KSXF 2I19A 3UCAA 3ZCDA 3M00A 1RTRA 3LEEA 5IKHA 1YYQA 3DYHA 1PS1A 1WMWA 3WCDA 5DHIA 3N0FA 1YYUA 3BNXA 3DYFA 2Q9ZA 2Z7IA 3WEKA 2F7MF 3NPRA 1VG6A 3Q30A 4RXCA 3ZL6A 1HM4A 2Z52A 2Q9YA 3LGZB 2PS7A 1N1BA 4DEMF 5IM1A 4Q23A 3G4FA 1DI1A 1UBYA 3ASXA 3LDWA 3LLWA 3WCFA 3LOMA 1YQ7A 3N5HF 5ER8A 3PH7A 2F8ZF 5ILYA 5IL8A 1YYSA 1YHLA 3OACA 2E93A 3P5PA 3S9VA 5DJRF 5ERMA 4MC0A 4LOBA 3VJ8A 2J1PA 2E8XA 2F89F 2AELA 4JXYA 3VJEA 3M9UA 4NFKF 4LPGF 3APZA 3WEFA 3KROB 5A0IA 3VJBA 5HN9A 3RYEA 1RQJA 5JV2F 3N6KF 1HM7A 5DGSF 3OABA 2ZEUA 4KQUA 3N5JF 5B01A 3N1VF 1HXCA 4H5EF 3ADZA 3N45F 3VJ9A 5JV0F 3P8RA 4OMHA 4LTVA 2ONHA 4LPHF 4LTZA 5HN7A 3ACWA
chains in the Genus database with same CATH topology
3W7FA 5IVGA 5ILIA 1ZW5A 4E9UA 3LK5A 3TFVA 1DGPA 5JV1F 2O1OA 3KRCB 4OKZA 4E9ZA 5DW7A 2F8CF 4NG6A 1N24A 2ZCSA 1VG4A 5EROA 2PS5A 2Z4YA 2PS6A 5IN8A 3TC1A 4KPDA 2ZCRA 3WEHA 3PDEA 3WCAA 3WEIA 3M0GA 3SDQA 3Q2ZA 4LLTA 3TFNA 2OGDA 4KQ5A 2E8TA 4P0XA 4F6VA 2AETA 3MAVA 5HN8A 2RAHA 1N1ZA 3N3DA 3SAEA 2Q58A 5EATA 3AQ0A 5B02A 3N46F 3ICMA 1N21A 3EZ3A 5DHKA 4KKMA 1V4JA 3WEJA 3WC9A 1UBWA 2E8UA 1YV5A 3QQVA 3VJDA 4EA0A 1WKZA 4NKEA 1V4KA 4EA2A 4KVWA 3WCBA 3Q1OA 5ILJA 3KBKA 2Z7HA 3SDRA 3ZMCA 3B7LA 3WCJA 2ZY1A 1UBXA 4LUUA 4NFIF 5CG5A 1FPSA 1VG3A 4KK2A 2E94A 1HXGA 3WJKA 5ERNA 3WCIA 1V4IA 3RMGA 4HD1A 1YYRA 2E8WA 4LFGA 5JA0F 3KB9A 3OACB 3WCGA 1KIYA 4DWBA 2ONGA 3V66A 5EASA 2Z50A 4DI5A 3N0GA 4MC8A 2PS4A 5DZ2A 5IMIA 3ICZA 3M02A 4GP2A 1YJ4A 4OKMA 3WSAA 3KRPA 5IK6A 3WCHA 4GAXA 3KRFA 4ZQ8A 5ILHA 5AELA 5A0KA 4RNQA 3OABB 5B0KA 1UBVA 3KRPB 2E90A 4KUXA 2FTZA 4KWDA 2J1OA 5AHUB 3KRFB 4JVJF 5AYPA 2E4OA 1RQIA 5E8LA 3ICNA 4JXNA 4LA5A 5DGNF 4JZXA 4KQSA 3LSNA 2EWGA 3DYGA 4K10A 3TFPA 5B0IA 3P8LA 5DGMF 5HNAA 5IMPA 1VG7A 5I1UA 3S4JA 2OPNA 5ILZA 3ID0A 3CKEA 3LZ9A 3WCMA 4RYPA 2F9KF 3WEGA 3BNYA 5E8HA 3LJIA 3NF2A 4N9UA 3SDVA 4F62A 5H9DA 4F6XA 5IL3A 4LZ3A 1KIZA 2J5CA 5C05A 1JFGA 4LZ0A 4DHDA 2ZCQA 3AQCB 4NUAA 3SDUA 4QXSF 3TS7A 4N1ZF 3PYBA 5B0MA 2AZLA 3ACXA 1YHMA 2Z4WA 4LFVF 4DWGA 4PVYF 3VJCA 4LA6A 3RYWA 4DXJA 1WY0A 3WE9A 1WL0A 4PVXF 2Z4ZA 4GA3A 3WCCA 2ZEVA 4KPJA 4UMJA 4P0VA 3LGKA 4KVIA 4OGUA 2DH4A 3P5RA 2AZJA 2OA6A 4GP1A 2Z78A 3N3LF 1HX9A 3EFQA 3Q2QA 2F94F 1N23A 3AQBB 3NPKA 4XQRF 4JZBA 5A0JA 4LLSA 1YHKA 3P41A 1WL1A 4RXDA 5B0LA 3ZMBA 2OPMA 3V1VA 4KFAA 4H5CF 5IK0A 2E8VA 3SDTA 4RXAA 4E1EA 3NRIA 1YYTA 3IBAA 2Z4VA 5IMNA 2P1CA 4H5DF 2F92F 5E8KA 3V1XA 3PYAA 2E92A 1VG2A 2VF6A 3KRAA 3QKCA 2E91A 3G4DA 3LVSA 4LZCA 5ILKA 3KRAB 5JUZF 2AZKA 2AEKA 2QISA 3KROA 3WSBA 5DIQF 5B03A 4LXWA 4P0WA 3CP6A 3RBMA 1N20A 3EGTA 2H8OA 1WL2A 3LMDA 5IKAA 4FJQA 5AFXA 4QPFA 1WL3A 3N49F 4KVYA 5DJPF 5EAUA 4NFJF 2E95A 3N1WF 4LFEA 4XQSF 5CG6A 2Q80A 3M01A 3KRCA 3PKOA 3WJOA 4WK5A 3WJNA 3WCLA 3VJAA 4L2XF 5B00A 1JFAA 1V4HA 2Z4XA 4LIXA 5B0JA 3WCEA 3ICKA 1V4EA 3MZVA 3IPIA 5ILDA 4EA1A 4JYXA 1EZFA 2PS8A 3OYRA 5DJVF 4DZWA 2ZCOA 5IK9A 2FORA 4RXEA 4XQTF 4MC3A 1N22A 4KVDA 3CC9A 4NKFA 3ACYA 4FP4A 3AE0A 3LG5A 3ZOUA 4OMGA 1HXAA 5KSXF 2I19A 3UCAA 3ZCDA 3M00A 1RTRA 3LEEA 5IKHA 1YYQA 3DYHA 1PS1A 1WMWA 3WCDA 5DHIA 3N0FA 1YYUA 3BNXA 3DYFA 2Q9ZA 2Z7IA 3WEKA 2F7MF 3NPRA 1VG6A 3Q30A 4RXCA 3ZL6A 1HM4A 2Z52A 2Q9YA 3LGZB 2PS7A 1N1BA 4DEMF 5IM1A 4Q23A 3G4FA 1DI1A 1UBYA 3ASXA 3LDWA 3LLWA 3WCFA 3LOMA 1YQ7A 3N5HF 5ER8A 3PH7A 2F8ZF 5ILYA 5IL8A 1YYSA 1YHLA 3OACA 2E93A 3P5PA 3S9VA 5DJRF 5ERMA 4MC0A 4LOBA 3VJ8A 2J1PA 2E8XA 2F89F 2AELA 4JXYA 3VJEA 3M9UA 4NFKF 4LPGF 3APZA 3WEFA 3KROB 5A0IA 3VJBA 5HN9A 3RYEA 1RQJA 5JV2F 3N6KF 1HM7A 5DGSF 3OABA 2ZEUA 4KQUA 3N5JF 5B01A 3N1VF 1HXCA 4H5EF 3ADZA 3N45F 3VJ9A 5JV0F 3P8RA 4OMHA 4LTVA 2ONHA 4LPHF 4LTZA 5HN7A 3ACWA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3W7F A;  5IVG A;  5ILI A;  1ZW5 A;  4E9U A;  3LK5 A;  3TFV A;  1DGP A;  5JV1 F;  2O1O A;  3KRC B;  4OKZ A;  4E9Z A;  5DW7 A;  2F8C F;  4NG6 A;  1N24 A;  2ZCS A;  1VG4 A;  5ERO A;  2PS5 A;  2Z4Y A;  2PS6 A;  5IN8 A;  3TC1 A;  4KPD A;  2ZCR A;  3WEH A;  3PDE A;  3WCA A;  3WEI A;  3M0G A;  3SDQ A;  3Q2Z A;  4LLT A;  3TFN A;  2OGD A;  4KQ5 A;  2E8T A;  4P0X A;  4F6V A;  2AET A;  3MAV A;  5HN8 A;  2RAH A;  1N1Z A;  3N3D A;  3SAE A;  2Q58 A;  5EAT A;  3AQ0 A;  5B02 A;  3N46 F;  3ICM A;  1N21 A;  3EZ3 A;  5DHK A;  4KKM A;  1V4J A;  3WEJ A;  3WC9 A;  1UBW A;  2E8U A;  1YV5 A;  3QQV A;  3VJD A;  4EA0 A;  1WKZ A;  4NKE A;  1V4K A;  4EA2 A;  4KVW A;  3WCB A;  3Q1O A;  5ILJ A;  3KBK A;  2Z7H A;  3SDR A;  3ZMC A;  3B7L A;  3WCJ A;  2ZY1 A;  1UBX A;  4LUU A;  4NFI F;  5CG5 A;  1FPS A;  1VG3 A;  4KK2 A;  2E94 A;  1HXG A;  3WJK A;  5ERN A;  3WCI A;  1V4I A;  3RMG A;  4HD1 A;  1YYR A;  2E8W A;  4LFG A;  5JA0 F;  3KB9 A;  3OAC B;  3WCG A;  1KIY A;  4DWB A;  2ONG A;  3V66 A;  5EAS A;  2Z50 A;  4DI5 A;  3N0G A;  4MC8 A;  2PS4 A;  5DZ2 A;  5IMI A;  3ICZ A;  3M02 A;  4GP2 A;  1YJ4 A;  4OKM A;  3WSA A;  3KRP A;  5IK6 A;  3WCH A;  4GAX A;  3KRF A;  4ZQ8 A;  5ILH A;  5AEL A;  5A0K A;  4RNQ A;  3OAB B;  5B0K A;  1UBV A;  3KRP B;  2E90 A;  4KUX A;  2FTZ A;  4KWD A;  2J1O A;  5AHU B;  3KRF B;  4JVJ F;  5AYP A;  2E4O A;  1RQI A;  5E8L A;  3ICN A;  4JXN A;  4LA5 A;  5DGN F;  4JZX A;  4KQS A;  3LSN A;  2EWG A;  3DYG A;  4K10 A;  3TFP A;  5B0I A;  3P8L A;  5DGM F;  5HNA A;  5IMP A;  1VG7 A;  5I1U A;  3S4J A;  2OPN A;  5ILZ A;  3ID0 A;  3CKE A;  3LZ9 A;  3WCM A;  4RYP A;  2F9K F;  3WEG A;  3BNY A;  5E8H A;  3LJI A;  3NF2 A;  4N9U A;  3SDV A;  4F62 A;  5H9D A;  4F6X A;  5IL3 A;  4LZ3 A;  1KIZ A;  2J5C A;  5C05 A;  1JFG A;  4LZ0 A;  4DHD A;  2ZCQ A;  3AQC B;  4NUA A;  3SDU A;  4QXS F;  3TS7 A;  4N1Z F;  3PYB A;  5B0M A;  2AZL A;  3ACX A;  1YHM A;  2Z4W A;  4LFV F;  4DWG A;  4PVY F;  3VJC A;  4LA6 A;  3RYW A;  4DXJ A;  1WY0 A;  3WE9 A;  1WL0 A;  4PVX F;  2Z4Z A;  4GA3 A;  3WCC A;  2ZEV A;  4KPJ A;  4UMJ A;  4P0V A;  3LGK A;  4KVI A;  4OGU A;  2DH4 A;  3P5R A;  2AZJ A;  2OA6 A;  4GP1 A;  2Z78 A;  3N3L F;  1HX9 A;  3EFQ A;  3Q2Q A;  2F94 F;  1N23 A;  3AQB B;  3NPK A;  4XQR F;  4JZB A;  5A0J A;  4LLS A;  1YHK A;  3P41 A;  1WL1 A;  4RXD A;  5B0L A;  3ZMB A;  2OPM A;  3V1V A;  4KFA A;  4H5C F;  5IK0 A;  2E8V A;  3SDT A;  4RXA A;  4E1E A;  3NRI A;  1YYT A;  3IBA A;  2Z4V A;  5IMN A;  2P1C A;  4H5D F;  2F92 F;  5E8K A;  3V1X A;  3PYA A;  2E92 A;  1VG2 A;  2VF6 A;  3KRA A;  3QKC A;  2E91 A;  3G4D A;  3LVS A;  4LZC A;  5ILK A;  3KRA B;  5JUZ F;  2AZK A;  2AEK A;  2QIS A;  3KRO A;  3WSB A;  5DIQ F;  5B03 A;  4LXW A;  4P0W A;  3CP6 A;  3RBM A;  1N20 A;  3EGT A;  2H8O A;  1WL2 A;  3LMD A;  5IKA A;  4FJQ A;  5AFX A;  4QPF A;  1WL3 A;  3N49 F;  4KVY A;  5DJP F;  5EAU A;  4NFJ F;  2E95 A;  3N1W F;  4LFE A;  4XQS F;  5CG6 A;  2Q80 A;  3M01 A;  3KRC A;  3PKO A;  3WJO A;  4WK5 A;  3WJN A;  3WCL A;  3VJA A;  4L2X F;  5B00 A;  1JFA A;  1V4H A;  2Z4X A;  4LIX A;  5B0J A;  3WCE A;  3ICK A;  1V4E A;  3MZV A;  3IPI A;  5ILD A;  4EA1 A;  4JYX A;  1EZF A;  2PS8 A;  3OYR A;  5DJV F;  4DZW A;  2ZCO A;  5IK9 A;  2FOR A;  4RXE A;  4XQT F;  4MC3 A;  1N22 A;  4KVD A;  3CC9 A;  4NKF A;  3ACY A;  4FP4 A;  3AE0 A;  3LG5 A;  3ZOU A;  4OMG A;  1HXA A;  5KSX F;  2I19 A;  3UCA A;  3ZCD A;  3M00 A;  1RTR A;  3LEE A;  5IKH A;  1YYQ A;  3DYH A;  1PS1 A;  1WMW A;  3WCD A;  5DHI A;  3N0F A;  1YYU A;  3BNX A;  3DYF A;  2Q9Z A;  2Z7I A;  3WEK A;  2F7M F;  3NPR A;  1VG6 A;  3Q30 A;  4RXC A;  3ZL6 A;  1HM4 A;  2Z52 A;  2Q9Y A;  3LGZ B;  2PS7 A;  1N1B A;  4DEM F;  5IM1 A;  4Q23 A;  3G4F A;  1DI1 A;  1UBY A;  3ASX A;  3LDW A;  3LLW A;  3WCF A;  3LOM A;  1YQ7 A;  3N5H F;  5ER8 A;  3PH7 A;  2F8Z F;  5ILY A;  5IL8 A;  1YYS A;  1YHL A;  3OAC A;  2E93 A;  3P5P A;  3S9V A;  5DJR F;  5ERM A;  4MC0 A;  4LOB A;  3VJ8 A;  2J1P A;  2E8X A;  2F89 F;  2AEL A;  4JXY A;  3VJE A;  3M9U A;  4NFK F;  4LPG F;  3APZ A;  3WEF A;  3KRO B;  5A0I A;  3VJB A;  5HN9 A;  3RYE A;  1RQJ A;  5JV2 F;  3N6K F;  1HM7 A;  5DGS F;  3OAB A;  2ZEU A;  4KQU A;  3N5J F;  5B01 A;  3N1V F;  1HXC A;  4H5E F;  3ADZ A;  3N45 F;  3VJ9 A;  5JV0 F;  3P8R A;  4OMH A;  4LTV A;  2ONH A;  4LPH F;  4LTZ A;  5HN7 A;  3ACW A; 
#chains in the Genus database with same CATH topology
 3W7F A;  5IVG A;  5ILI A;  1ZW5 A;  4E9U A;  3LK5 A;  3TFV A;  1DGP A;  5JV1 F;  2O1O A;  3KRC B;  4OKZ A;  4E9Z A;  5DW7 A;  2F8C F;  4NG6 A;  1N24 A;  2ZCS A;  1VG4 A;  5ERO A;  2PS5 A;  2Z4Y A;  2PS6 A;  5IN8 A;  3TC1 A;  4KPD A;  2ZCR A;  3WEH A;  3PDE A;  3WCA A;  3WEI A;  3M0G A;  3SDQ A;  3Q2Z A;  4LLT A;  3TFN A;  2OGD A;  4KQ5 A;  2E8T A;  4P0X A;  4F6V A;  2AET A;  3MAV A;  5HN8 A;  2RAH A;  1N1Z A;  3N3D A;  3SAE A;  2Q58 A;  5EAT A;  3AQ0 A;  5B02 A;  3N46 F;  3ICM A;  1N21 A;  3EZ3 A;  5DHK A;  4KKM A;  1V4J A;  3WEJ A;  3WC9 A;  1UBW A;  2E8U A;  1YV5 A;  3QQV A;  3VJD A;  4EA0 A;  1WKZ A;  4NKE A;  1V4K A;  4EA2 A;  4KVW A;  3WCB A;  3Q1O A;  5ILJ A;  3KBK A;  2Z7H A;  3SDR A;  3ZMC A;  3B7L A;  3WCJ A;  2ZY1 A;  1UBX A;  4LUU A;  4NFI F;  5CG5 A;  1FPS A;  1VG3 A;  4KK2 A;  2E94 A;  1HXG A;  3WJK A;  5ERN A;  3WCI A;  1V4I A;  3RMG A;  4HD1 A;  1YYR A;  2E8W A;  4LFG A;  5JA0 F;  3KB9 A;  3OAC B;  3WCG A;  1KIY A;  4DWB A;  2ONG A;  3V66 A;  5EAS A;  2Z50 A;  4DI5 A;  3N0G A;  4MC8 A;  2PS4 A;  5DZ2 A;  5IMI A;  3ICZ A;  3M02 A;  4GP2 A;  1YJ4 A;  4OKM A;  3WSA A;  3KRP A;  5IK6 A;  3WCH A;  4GAX A;  3KRF A;  4ZQ8 A;  5ILH A;  5AEL A;  5A0K A;  4RNQ A;  3OAB B;  5B0K A;  1UBV A;  3KRP B;  2E90 A;  4KUX A;  2FTZ A;  4KWD A;  2J1O A;  5AHU B;  3KRF B;  4JVJ F;  5AYP A;  2E4O A;  1RQI A;  5E8L A;  3ICN A;  4JXN A;  4LA5 A;  5DGN F;  4JZX A;  4KQS A;  3LSN A;  2EWG A;  3DYG A;  4K10 A;  3TFP A;  5B0I A;  3P8L A;  5DGM F;  5HNA A;  5IMP A;  1VG7 A;  5I1U A;  3S4J A;  2OPN A;  5ILZ A;  3ID0 A;  3CKE A;  3LZ9 A;  3WCM A;  4RYP A;  2F9K F;  3WEG A;  3BNY A;  5E8H A;  3LJI A;  3NF2 A;  4N9U A;  3SDV A;  4F62 A;  5H9D A;  4F6X A;  5IL3 A;  4LZ3 A;  1KIZ A;  2J5C A;  5C05 A;  1JFG A;  4LZ0 A;  4DHD A;  2ZCQ A;  3AQC B;  4NUA A;  3SDU A;  4QXS F;  3TS7 A;  4N1Z F;  3PYB A;  5B0M A;  2AZL A;  3ACX A;  1YHM A;  2Z4W A;  4LFV F;  4DWG A;  4PVY F;  3VJC A;  4LA6 A;  3RYW A;  4DXJ A;  1WY0 A;  3WE9 A;  1WL0 A;  4PVX F;  2Z4Z A;  4GA3 A;  3WCC A;  2ZEV A;  4KPJ A;  4UMJ A;  4P0V A;  3LGK A;  4KVI A;  4OGU A;  2DH4 A;  3P5R A;  2AZJ A;  2OA6 A;  4GP1 A;  2Z78 A;  3N3L F;  1HX9 A;  3EFQ A;  3Q2Q A;  2F94 F;  1N23 A;  3AQB B;  3NPK A;  4XQR F;  4JZB A;  5A0J A;  4LLS A;  1YHK A;  3P41 A;  1WL1 A;  4RXD A;  5B0L A;  3ZMB A;  2OPM A;  3V1V A;  4KFA A;  4H5C F;  5IK0 A;  2E8V A;  3SDT A;  4RXA A;  4E1E A;  3NRI A;  1YYT A;  3IBA A;  2Z4V A;  5IMN A;  2P1C A;  4H5D F;  2F92 F;  5E8K A;  3V1X A;  3PYA A;  2E92 A;  1VG2 A;  2VF6 A;  3KRA A;  3QKC A;  2E91 A;  3G4D A;  3LVS A;  4LZC A;  5ILK A;  3KRA B;  5JUZ F;  2AZK A;  2AEK A;  2QIS A;  3KRO A;  3WSB A;  5DIQ F;  5B03 A;  4LXW A;  4P0W A;  3CP6 A;  3RBM A;  1N20 A;  3EGT A;  2H8O A;  1WL2 A;  3LMD A;  5IKA A;  4FJQ A;  5AFX A;  4QPF A;  1WL3 A;  3N49 F;  4KVY A;  5DJP F;  5EAU A;  4NFJ F;  2E95 A;  3N1W F;  4LFE A;  4XQS F;  5CG6 A;  2Q80 A;  3M01 A;  3KRC A;  3PKO A;  3WJO A;  4WK5 A;  3WJN A;  3WCL A;  3VJA A;  4L2X F;  5B00 A;  1JFA A;  1V4H A;  2Z4X A;  4LIX A;  5B0J A;  3WCE A;  3ICK A;  1V4E A;  3MZV A;  3IPI A;  5ILD A;  4EA1 A;  4JYX A;  1EZF A;  2PS8 A;  3OYR A;  5DJV F;  4DZW A;  2ZCO A;  5IK9 A;  2FOR A;  4RXE A;  4XQT F;  4MC3 A;  1N22 A;  4KVD A;  3CC9 A;  4NKF A;  3ACY A;  4FP4 A;  3AE0 A;  3LG5 A;  3ZOU A;  4OMG A;  1HXA A;  5KSX F;  2I19 A;  3UCA A;  3ZCD A;  3M00 A;  1RTR A;  3LEE A;  5IKH A;  1YYQ A;  3DYH A;  1PS1 A;  1WMW A;  3WCD A;  5DHI A;  3N0F A;  1YYU A;  3BNX A;  3DYF A;  2Q9Z A;  2Z7I A;  3WEK A;  2F7M F;  3NPR A;  1VG6 A;  3Q30 A;  4RXC A;  3ZL6 A;  1HM4 A;  2Z52 A;  2Q9Y A;  3LGZ B;  2PS7 A;  1N1B A;  4DEM F;  5IM1 A;  4Q23 A;  3G4F A;  1DI1 A;  1UBY A;  3ASX A;  3LDW A;  3LLW A;  3WCF A;  3LOM A;  1YQ7 A;  3N5H F;  5ER8 A;  3PH7 A;  2F8Z F;  5ILY A;  5IL8 A;  1YYS A;  1YHL A;  3OAC A;  2E93 A;  3P5P A;  3S9V A;  5DJR F;  5ERM A;  4MC0 A;  4LOB A;  3VJ8 A;  2J1P A;  2E8X A;  2F89 F;  2AEL A;  4JXY A;  3VJE A;  3M9U A;  4NFK F;  4LPG F;  3APZ A;  3WEF A;  3KRO B;  5A0I A;  3VJB A;  5HN9 A;  3RYE A;  1RQJ A;  5JV2 F;  3N6K F;  1HM7 A;  5DGS F;  3OAB A;  2ZEU A;  4KQU A;  3N5J F;  5B01 A;  3N1V F;  1HXC A;  4H5E F;  3ADZ A;  3N45 F;  3VJ9 A;  5JV0 F;  3P8R A;  4OMH A;  4LTV A;  2ONH A;  4LPH F;  4LTZ A;  5HN7 A;  3ACW A; 
#chains in the Genus database with same CATH homology
 3W7F A;  5IVG A;  5ILI A;  1ZW5 A;  4E9U A;  3LK5 A;  3TFV A;  1DGP A;  5JV1 F;  2O1O A;  3KRC B;  4OKZ A;  4E9Z A;  5DW7 A;  2F8C F;  4NG6 A;  1N24 A;  2ZCS A;  1VG4 A;  5ERO A;  2PS5 A;  2Z4Y A;  2PS6 A;  5IN8 A;  3TC1 A;  4KPD A;  2ZCR A;  3WEH A;  3PDE A;  3WCA A;  3WEI A;  3M0G A;  3SDQ A;  3Q2Z A;  4LLT A;  3TFN A;  2OGD A;  4KQ5 A;  2E8T A;  4P0X A;  4F6V A;  2AET A;  3MAV A;  5HN8 A;  2RAH A;  1N1Z A;  3N3D A;  3SAE A;  2Q58 A;  5EAT A;  3AQ0 A;  5B02 A;  3N46 F;  3ICM A;  1N21 A;  3EZ3 A;  5DHK A;  4KKM A;  1V4J A;  3WEJ A;  3WC9 A;  1UBW A;  2E8U A;  1YV5 A;  3QQV A;  3VJD A;  4EA0 A;  1WKZ A;  4NKE A;  1V4K A;  4EA2 A;  4KVW A;  3WCB A;  3Q1O A;  5ILJ A;  3KBK A;  2Z7H A;  3SDR A;  3ZMC A;  3B7L A;  3WCJ A;  2ZY1 A;  1UBX A;  4LUU A;  4NFI F;  5CG5 A;  1FPS A;  1VG3 A;  4KK2 A;  2E94 A;  1HXG A;  3WJK A;  5ERN A;  3WCI A;  1V4I A;  3RMG A;  4HD1 A;  1YYR A;  2E8W A;  4LFG A;  5JA0 F;  3KB9 A;  3OAC B;  3WCG A;  1KIY A;  4DWB A;  2ONG A;  3V66 A;  5EAS A;  2Z50 A;  4DI5 A;  3N0G A;  4MC8 A;  2PS4 A;  5DZ2 A;  5IMI A;  3ICZ A;  3M02 A;  4GP2 A;  1YJ4 A;  4OKM A;  3WSA A;  3KRP A;  5IK6 A;  3WCH A;  4GAX A;  3KRF A;  4ZQ8 A;  5ILH A;  5AEL A;  5A0K A;  4RNQ A;  3OAB B;  5B0K A;  1UBV A;  3KRP B;  2E90 A;  4KUX A;  2FTZ A;  4KWD A;  2J1O A;  5AHU B;  3KRF B;  4JVJ F;  5AYP A;  2E4O A;  1RQI A;  5E8L A;  3ICN A;  4JXN A;  4LA5 A;  5DGN F;  4JZX A;  4KQS A;  3LSN A;  2EWG A;  3DYG A;  4K10 A;  3TFP A;  5B0I A;  3P8L A;  5DGM F;  5HNA A;  5IMP A;  1VG7 A;  5I1U A;  3S4J A;  2OPN A;  5ILZ A;  3ID0 A;  3CKE A;  3LZ9 A;  3WCM A;  4RYP A;  2F9K F;  3WEG A;  3BNY A;  5E8H A;  3LJI A;  3NF2 A;  4N9U A;  3SDV A;  4F62 A;  5H9D A;  4F6X A;  5IL3 A;  4LZ3 A;  1KIZ A;  2J5C A;  5C05 A;  1JFG A;  4LZ0 A;  4DHD A;  2ZCQ A;  3AQC B;  4NUA A;  3SDU A;  4QXS F;  3TS7 A;  4N1Z F;  3PYB A;  5B0M A;  2AZL A;  3ACX A;  1YHM A;  2Z4W A;  4LFV F;  4DWG A;  4PVY F;  3VJC A;  4LA6 A;  3RYW A;  4DXJ A;  1WY0 A;  3WE9 A;  1WL0 A;  4PVX F;  2Z4Z A;  4GA3 A;  3WCC A;  2ZEV A;  4KPJ A;  4UMJ A;  4P0V A;  3LGK A;  4KVI A;  4OGU A;  2DH4 A;  3P5R A;  2AZJ A;  2OA6 A;  4GP1 A;  2Z78 A;  3N3L F;  1HX9 A;  3EFQ A;  3Q2Q A;  2F94 F;  1N23 A;  3AQB B;  3NPK A;  4XQR F;  4JZB A;  5A0J A;  4LLS A;  1YHK A;  3P41 A;  1WL1 A;  4RXD A;  5B0L A;  3ZMB A;  2OPM A;  3V1V A;  4KFA A;  4H5C F;  5IK0 A;  2E8V A;  3SDT A;  4RXA A;  4E1E A;  3NRI A;  1YYT A;  3IBA A;  2Z4V A;  5IMN A;  2P1C A;  4H5D F;  2F92 F;  5E8K A;  3V1X A;  3PYA A;  2E92 A;  1VG2 A;  2VF6 A;  3KRA A;  3QKC A;  2E91 A;  3G4D A;  3LVS A;  4LZC A;  5ILK A;  3KRA B;  5JUZ F;  2AZK A;  2AEK A;  2QIS A;  3KRO A;  3WSB A;  5DIQ F;  5B03 A;  4LXW A;  4P0W A;  3CP6 A;  3RBM A;  1N20 A;  3EGT A;  2H8O A;  1WL2 A;  3LMD A;  5IKA A;  4FJQ A;  5AFX A;  4QPF A;  1WL3 A;  3N49 F;  4KVY A;  5DJP F;  5EAU A;  4NFJ F;  2E95 A;  3N1W F;  4LFE A;  4XQS F;  5CG6 A;  2Q80 A;  3M01 A;  3KRC A;  3PKO A;  3WJO A;  4WK5 A;  3WJN A;  3WCL A;  3VJA A;  4L2X F;  5B00 A;  1JFA A;  1V4H A;  2Z4X A;  4LIX A;  5B0J A;  3WCE A;  3ICK A;  1V4E A;  3MZV A;  3IPI A;  5ILD A;  4EA1 A;  4JYX A;  1EZF A;  2PS8 A;  3OYR A;  5DJV F;  4DZW A;  2ZCO A;  5IK9 A;  2FOR A;  4RXE A;  4XQT F;  4MC3 A;  1N22 A;  4KVD A;  3CC9 A;  4NKF A;  3ACY A;  4FP4 A;  3AE0 A;  3LG5 A;  3ZOU A;  4OMG A;  1HXA A;  5KSX F;  2I19 A;  3UCA A;  3ZCD A;  3M00 A;  1RTR A;  3LEE A;  5IKH A;  1YYQ A;  3DYH A;  1PS1 A;  1WMW A;  3WCD A;  5DHI A;  3N0F A;  1YYU A;  3BNX A;  3DYF A;  2Q9Z A;  2Z7I A;  3WEK A;  2F7M F;  3NPR A;  1VG6 A;  3Q30 A;  4RXC A;  3ZL6 A;  1HM4 A;  2Z52 A;  2Q9Y A;  3LGZ B;  2PS7 A;  1N1B A;  4DEM F;  5IM1 A;  4Q23 A;  3G4F A;  1DI1 A;  1UBY A;  3ASX A;  3LDW A;  3LLW A;  3WCF A;  3LOM A;  1YQ7 A;  3N5H F;  5ER8 A;  3PH7 A;  2F8Z F;  5ILY A;  5IL8 A;  1YYS A;  1YHL A;  3OAC A;  2E93 A;  3P5P A;  3S9V A;  5DJR F;  5ERM A;  4MC0 A;  4LOB A;  3VJ8 A;  2J1P A;  2E8X A;  2F89 F;  2AEL A;  4JXY A;  3VJE A;  3M9U A;  4NFK F;  4LPG F;  3APZ A;  3WEF A;  3KRO B;  5A0I A;  3VJB A;  5HN9 A;  3RYE A;  1RQJ A;  5JV2 F;  3N6K F;  1HM7 A;  5DGS F;  3OAB A;  2ZEU A;  4KQU A;  3N5J F;  5B01 A;  3N1V F;  1HXC A;  4H5E F;  3ADZ A;  3N45 F;  3VJ9 A;  5JV0 F;  3P8R A;  4OMH A;  4LTV A;  2ONH A;  4LPH F;  4LTZ A;  5HN7 A;  3ACW A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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