4K10A

Crystal structure of leshmaniasis major farnesyl diphosphate synthase in complex with 3-fluoro-1-(2-hydroxy-2,2-diphosphonoethyl)pyridinium and mg2+
Total Genus 146
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
146
sequence length
361
structure length
358
Chain Sequence
MAHMERFQKVYEEVQEFLLGDAEKRFEMDVHRKGYLKSMMDTTCLGGKYNRGLCVVDVAEAMAKDTQMDAAAMERVLHDACVCGWMIEMLQAHFLVEDDIMDHSKTRRGKPCWYLHPGVTAQVAINDGLILLAWATQMALHYFADRPFLAEVLRVFHDVDLTTTIGQLYDVTSMVDSAKLDAKVAHANTTDYVEYTPFNHRRIVVYKTAYYTYWLPLVMGLLVSGTLEKVDKKATHKVAMVMGEYFQVQDDVMDCFTPPEKIGTDIEDAKCSWLAVTFLTTAPAEKVAEFKANYGSTDPAAVAVIKQLYTEQNLLARFEEYEKAVVAEVEQLIAALEAQNAAFAASVKVLWSKTYKRQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
molecule keywords Farnesyl pyrophosphate synthase
publication title Structural and thermodynamic basis of the inhibition of Leishmania major farnesyl diphosphate synthase by nitrogen-containing bisphosphonates.
pubmed doi rcsb
source organism Leishmania major
total genus 146
structure length 358
sequence length 361
chains with identical sequence B, C, D
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2013-04-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4k10A00
3NPRA 5IKAA 5IMPA 4LIXA 3ICKA 4JXYA 4ZQ8A 5B0JA 1YYQA 3ACYA 4MC3A 4NKFA 4NUAA 1WY0A 1VG2A 3LK5A 2E93A 3LDWA 5ER8A 5B0KA 2F94F 3NRIA 4LTZA 2F89F 2VF6A 2OPMA 2E90A 2ONGA 3OABA 4DZWA 1PS1A 4WK5A 3N45F 4KPJA 5KSXF 4KQUA 1VG3A 4LPGF 3WCGA 4N9UA 3N5JF 3Q2QA 5IMIA 4NFJF 2ZY1A 3ICZA 5JA0F 3APZA 4OMGA 4NG6A 2Z4WA 2E92A 2ZEVA 1UBXA 3KRPA 2AEKA 4OMHA 1N20A 3N3LF 3KRCB 4L2XF 3RMGA 5DGNF 4LFVF 4P0VA 4NKEA 3N1VF 1N24A 3TFVA 5JV2F 3WCLA 3KBKA 3V1XA 5AFXA 4PVYF 4KK2A 5B0IA 3WCJA 5ILDA 1VG6A 2PS8A 3M9UA 3BNXA 1YYSA 5B0LA 4KVDA 3TFPA 3S4JA 1UBYA 4LZ0A 4EA2A 3WCDA 3N49F 3QKCA 1HXCA 2F7MF 2Z7IA 3N1WF 3NF2A 5B0MA 5JUZF 4LA5A 1WL1A 3WEKA 5CG6A 3KRFB 4GA3A 1YV5A 3CC9A 3WCAA 4XQSF 4XQRF 3MZVA 4LUUA 3ACWA 3Q2ZA 1N1BA 3Q1OA 3N3DA 3KRPB 2Z4YA 5I1UA 5A0IA 2PS7A 3ICNA 4LOBA 1YYTA 3TC1A 3LMDA 5C05A 3TS7A 2AZLA 1WL3A 3WJNA 4OGUA 2E94A 3ZL6A 5ERMA 3W7FA 5DIQF 3SAEA 4LA6A 1VG7A 2I19A 3LJIA 3WEFA 4NFIF 4DI5A 4FP4A 2FTZA 3AQ0A 3RYWA 2FORA 3G4DA 4P0XA 2Q80A 3OACA 4JZXA 5ILIA 4KKMA 1RQJA 4RXDA 2ZEUA 5IMNA 1YYUA 4KWDA 2DH4A 5HN8A 3VJ9A 4DHDA 5E8LA 4PVXF 5E8KA 4LXWA 4HD1A 3VJ8A 3SDQA 2H8OA 4RXCA 3KRFA 3DYHA 5ILZA 3P8RA 4JVJF 2E91A 2P1CA 5IKHA 3WCBA 2E8TA 1EZFA 5DZ2A 3SDVA 1VG4A 3PKOA 4MC8A 2E95A 2Z4XA 4LPHF 4RXEA 1ZW5A 5EAUA 3PYAA 3SDTA 1FPSA 5ILJA 3MAVA 2AZJA 3ADZA 1HM7A 1WKZA 4LZCA 3N46F 3VJEA 4XQTF 2J5CA 3KRAA 3LGKA 4UMJA 5IM1A 3PH7A 1YQ7A 3WCEA 2AELA 5DGSF 3OACB 3KB9A 1YHMA 4DXJA 2Z50A 1HX9A 5DJRF 5IK0A 2J1OA 2RAHA 1WL2A 2O1OA 4QXSF 5B01A 2Z52A 4K10A 2E8VA 5A0KA 4MC0A 1YYRA 5ERNA 2AZKA 3VJDA 3B7LA 5AYPA 1RQIA 1N22A 2PS4A 2OGDA 4KQ5A 5DHKA 2F8ZF 3LOMA 3V1VA 3VJAA 5CG5A 5H9DA 5HN7A 3WC9A 2Z4ZA 4F62A 4LLSA 3WSBA 3OYRA 4JXNA 5EASA 3WEIA 1JFGA 3IPIA 1N23A 5IK9A 3LLWA 4JZBA 3RYEA 4P0WA 4F6VA 4EA1A 4RNQA 3KRAB 2Q58A 1UBVA 3KROB 3WCCA 3NPKA 3WJOA 5JV1F 3WCFA 2J1PA 3ACXA 1YHKA 4DEMF 3M00A 1HXAA 4OKZA 3WE9A 1V4EA 4EA0A 1DI1A 3N5HF 3WSAA 5HN9A 2E8WA 4GAXA 3M02A 4E9UA 4GP2A 4KFAA 4KVWA 3G4FA 3PYBA 3WEGA 1KIYA 3EGTA 4LFGA 2Z78A 5ILKA 4Q23A 4E9ZA 5A0JA 3S9VA 5B02A 3BNYA 4QPFA 5AELA 3ASXA 3WEHA 3WCHA 4KUXA 4LFEA 4FJQA 1V4HA 4LZ3A 3AQCB 3PDEA 4H5EF 4DWBA 2E8UA 4H5DF 3LVSA 1YJ4A 3ZMBA 5ILHA 2ZCSA 3LGZB 1DGPA 3DYGA 3AQBB 4KVYA 3ZMCA 3LG5A 4KQSA 3SDRA 5EROA 3LZ9A 4F6XA 3V66A 3Q30A 2ZCOA 3KROA 4LTVA 2PS6A 4LLTA 1WL0A 1N21A 2ZCQA 5B00A 3N6KF 4DWGA 5IVGA 3LEEA 3UCAA 4JYXA 3ZCDA 4GP1A 1WMWA 1N1ZA 2ONHA 1RTRA 2OPNA 2Z4VA 2Q9ZA 1HM4A 4N1ZF 5JV0F 5ILYA 2AETA 3EFQA 3ID0A 2F92F 5DW7A 3P5RA 3M0GA 3ICMA 4OKMA 5AHUB 5EATA 5DHIA 1HXGA 5DJPF 3WJKA 3WCIA 3N0FA 3WCMA 1UBWA 4E1EA 3P41A 3OABB 3VJBA 3CP6A 2F8CF 3N0GA 4KPDA 3IBAA 3P8LA 1V4IA 5DGMF 3WEJA 2Z7HA 3M01A 5IN8A 3LSNA 5IK6A 5DJVF 1KIZA 2F9KF 3EZ3A 5B03A 5IL3A 4KVIA 1V4KA 2EWGA 1JFAA 5IL8A 3VJCA 2QISA 5HNAA 3QQVA 5E8HA 3RBMA 2OA6A 3P5PA 1YHLA 2ZCRA 4H5CF 4RYPA 3AE0A 3KRCA 3TFNA 4NFKF 2E4OA 3CKEA 2Q9YA 3SDUA 3ZOUA 2E8XA 2PS5A 4RXAA 3DYFA 1V4JA
chains in the Genus database with same CATH superfamily
3NPRA 5IKAA 5IMPA 4LIXA 3ICKA 4JXYA 4ZQ8A 5B0JA 1YYQA 3ACYA 4MC3A 4NKFA 4NUAA 1WY0A 1VG2A 3LK5A 2E93A 3LDWA 5ER8A 5B0KA 2F94F 3NRIA 4LTZA 2F89F 2VF6A 2OPMA 2E90A 2ONGA 3OABA 4DZWA 1PS1A 4WK5A 3N45F 4KPJA 5KSXF 4KQUA 1VG3A 4LPGF 3WCGA 4N9UA 3N5JF 3Q2QA 5IMIA 4NFJF 2ZY1A 3ICZA 5JA0F 3APZA 4OMGA 4NG6A 2Z4WA 2E92A 2ZEVA 1UBXA 3KRPA 2AEKA 4OMHA 1N20A 3N3LF 3KRCB 4L2XF 3RMGA 5DGNF 4LFVF 4P0VA 4NKEA 3N1VF 1N24A 3TFVA 5JV2F 3WCLA 3KBKA 3V1XA 5AFXA 4PVYF 4KK2A 5B0IA 3WCJA 5ILDA 1VG6A 2PS8A 3M9UA 3BNXA 1YYSA 5B0LA 4KVDA 3TFPA 3S4JA 1UBYA 4LZ0A 4EA2A 3WCDA 3N49F 3QKCA 1HXCA 2F7MF 2Z7IA 3N1WF 3NF2A 5B0MA 5JUZF 4LA5A 1WL1A 3WEKA 5CG6A 3KRFB 4GA3A 1YV5A 3CC9A 3WCAA 4XQSF 4XQRF 3MZVA 4LUUA 3ACWA 3Q2ZA 1N1BA 3Q1OA 3N3DA 3KRPB 2Z4YA 5I1UA 5A0IA 2PS7A 3ICNA 4LOBA 1YYTA 3TC1A 3LMDA 5C05A 3TS7A 2AZLA 1WL3A 3WJNA 4OGUA 2E94A 3ZL6A 5ERMA 3W7FA 5DIQF 3SAEA 4LA6A 1VG7A 2I19A 3LJIA 3WEFA 4NFIF 4DI5A 4FP4A 2FTZA 3AQ0A 3RYWA 2FORA 3G4DA 4P0XA 2Q80A 3OACA 4JZXA 5ILIA 4KKMA 1RQJA 4RXDA 2ZEUA 5IMNA 1YYUA 4KWDA 2DH4A 5HN8A 3VJ9A 4DHDA 5E8LA 4PVXF 5E8KA 4LXWA 4HD1A 3VJ8A 3SDQA 2H8OA 4RXCA 3KRFA 3DYHA 5ILZA 3P8RA 4JVJF 2E91A 2P1CA 5IKHA 3WCBA 2E8TA 1EZFA 5DZ2A 3SDVA 1VG4A 3PKOA 4MC8A 2E95A 2Z4XA 4LPHF 4RXEA 1ZW5A 5EAUA 3PYAA 3SDTA 1FPSA 5ILJA 3MAVA 2AZJA 3ADZA 1HM7A 1WKZA 4LZCA 3N46F 3VJEA 4XQTF 2J5CA 3KRAA 3LGKA 4UMJA 5IM1A 3PH7A 1YQ7A 3WCEA 2AELA 5DGSF 3OACB 3KB9A 1YHMA 4DXJA 2Z50A 1HX9A 5DJRF 5IK0A 2J1OA 2RAHA 1WL2A 2O1OA 4QXSF 5B01A 2Z52A 4K10A 2E8VA 5A0KA 4MC0A 1YYRA 5ERNA 2AZKA 3VJDA 3B7LA 5AYPA 1RQIA 1N22A 2PS4A 2OGDA 4KQ5A 5DHKA 2F8ZF 3LOMA 3V1VA 3VJAA 5CG5A 5H9DA 5HN7A 3WC9A 2Z4ZA 4F62A 4LLSA 3WSBA 3OYRA 4JXNA 5EASA 3WEIA 1JFGA 3IPIA 1N23A 5IK9A 3LLWA 4JZBA 3RYEA 4P0WA 4F6VA 4EA1A 4RNQA 3KRAB 2Q58A 1UBVA 3KROB 3WCCA 3NPKA 3WJOA 5JV1F 3WCFA 2J1PA 3ACXA 1YHKA 4DEMF 3M00A 1HXAA 4OKZA 3WE9A 1V4EA 4EA0A 1DI1A 3N5HF 3WSAA 5HN9A 2E8WA 4GAXA 3M02A 4E9UA 4GP2A 4KFAA 4KVWA 3G4FA 3PYBA 3WEGA 1KIYA 3EGTA 4LFGA 2Z78A 5ILKA 4Q23A 4E9ZA 5A0JA 3S9VA 5B02A 3BNYA 4QPFA 5AELA 3ASXA 3WEHA 3WCHA 4KUXA 4LFEA 4FJQA 1V4HA 4LZ3A 3AQCB 3PDEA 4H5EF 4DWBA 2E8UA 4H5DF 3LVSA 1YJ4A 3ZMBA 5ILHA 2ZCSA 3LGZB 1DGPA 3DYGA 3AQBB 4KVYA 3ZMCA 3LG5A 4KQSA 3SDRA 5EROA 3LZ9A 4F6XA 3V66A 3Q30A 2ZCOA 3KROA 4LTVA 2PS6A 4LLTA 1WL0A 1N21A 2ZCQA 5B00A 3N6KF 4DWGA 5IVGA 3LEEA 3UCAA 4JYXA 3ZCDA 4GP1A 1WMWA 1N1ZA 2ONHA 1RTRA 2OPNA 2Z4VA 2Q9ZA 1HM4A 4N1ZF 5JV0F 5ILYA 2AETA 3EFQA 3ID0A 2F92F 5DW7A 3P5RA 3M0GA 3ICMA 4OKMA 5AHUB 5EATA 5DHIA 1HXGA 5DJPF 3WJKA 3WCIA 3N0FA 3WCMA 1UBWA 4E1EA 3P41A 3OABB 3VJBA 3CP6A 2F8CF 3N0GA 4KPDA 3IBAA 3P8LA 1V4IA 5DGMF 3WEJA 2Z7HA 3M01A 5IN8A 3LSNA 5IK6A 5DJVF 1KIZA 2F9KF 3EZ3A 5B03A 5IL3A 4KVIA 1V4KA 2EWGA 1JFAA 5IL8A 3VJCA 2QISA 5HNAA 3QQVA 5E8HA 3RBMA 2OA6A 3P5PA 1YHLA 2ZCRA 4H5CF 4RYPA 3AE0A 3KRCA 3TFNA 4NFKF 2E4OA 3CKEA 2Q9YA 3SDUA 3ZOUA 2E8XA 2PS5A 4RXAA 3DYFA 1V4JA
chains in the Genus database with same CATH topology
3NPRA 5IKAA 5IMPA 4LIXA 3ICKA 4JXYA 4ZQ8A 5B0JA 1YYQA 3ACYA 4MC3A 4NKFA 4NUAA 1WY0A 1VG2A 3LK5A 2E93A 3LDWA 5ER8A 5B0KA 2F94F 3NRIA 4LTZA 2F89F 2VF6A 2OPMA 2E90A 2ONGA 3OABA 4DZWA 1PS1A 4WK5A 3N45F 4KPJA 5KSXF 4KQUA 1VG3A 4LPGF 3WCGA 4N9UA 3N5JF 3Q2QA 5IMIA 4NFJF 2ZY1A 3ICZA 5JA0F 3APZA 4OMGA 4NG6A 2Z4WA 2E92A 2ZEVA 1UBXA 3KRPA 2AEKA 4OMHA 1N20A 3N3LF 3KRCB 4L2XF 3RMGA 5DGNF 4LFVF 4P0VA 4NKEA 3N1VF 1N24A 3TFVA 5JV2F 3WCLA 3KBKA 3V1XA 5AFXA 4PVYF 4KK2A 5B0IA 3WCJA 5ILDA 1VG6A 2PS8A 3M9UA 3BNXA 1YYSA 5B0LA 4KVDA 3TFPA 3S4JA 1UBYA 4LZ0A 4EA2A 3WCDA 3N49F 3QKCA 1HXCA 2F7MF 2Z7IA 3N1WF 3NF2A 5B0MA 5JUZF 4LA5A 1WL1A 3WEKA 5CG6A 3KRFB 4GA3A 1YV5A 3CC9A 3WCAA 4XQSF 4XQRF 3MZVA 4LUUA 3ACWA 3Q2ZA 1N1BA 3Q1OA 3N3DA 3KRPB 2Z4YA 5I1UA 5A0IA 2PS7A 3ICNA 4LOBA 1YYTA 3TC1A 3LMDA 5C05A 3TS7A 2AZLA 1WL3A 3WJNA 4OGUA 2E94A 3ZL6A 5ERMA 3W7FA 5DIQF 3SAEA 4LA6A 1VG7A 2I19A 3LJIA 3WEFA 4NFIF 4DI5A 4FP4A 2FTZA 3AQ0A 3RYWA 2FORA 3G4DA 4P0XA 2Q80A 3OACA 4JZXA 5ILIA 4KKMA 1RQJA 4RXDA 2ZEUA 5IMNA 1YYUA 4KWDA 2DH4A 5HN8A 3VJ9A 4DHDA 5E8LA 4PVXF 5E8KA 4LXWA 4HD1A 3VJ8A 3SDQA 2H8OA 4RXCA 3KRFA 3DYHA 5ILZA 3P8RA 4JVJF 2E91A 2P1CA 5IKHA 3WCBA 2E8TA 1EZFA 5DZ2A 3SDVA 1VG4A 3PKOA 4MC8A 2E95A 2Z4XA 4LPHF 4RXEA 1ZW5A 5EAUA 3PYAA 3SDTA 1FPSA 5ILJA 3MAVA 2AZJA 3ADZA 1HM7A 1WKZA 4LZCA 3N46F 3VJEA 4XQTF 2J5CA 3KRAA 3LGKA 4UMJA 5IM1A 3PH7A 1YQ7A 3WCEA 2AELA 5DGSF 3OACB 3KB9A 1YHMA 4DXJA 2Z50A 1HX9A 5DJRF 5IK0A 2J1OA 2RAHA 1WL2A 2O1OA 4QXSF 5B01A 2Z52A 4K10A 2E8VA 5A0KA 4MC0A 1YYRA 5ERNA 2AZKA 3VJDA 3B7LA 5AYPA 1RQIA 1N22A 2PS4A 2OGDA 4KQ5A 5DHKA 2F8ZF 3LOMA 3V1VA 3VJAA 5CG5A 5H9DA 5HN7A 3WC9A 2Z4ZA 4F62A 4LLSA 3WSBA 3OYRA 4JXNA 5EASA 3WEIA 1JFGA 3IPIA 1N23A 5IK9A 3LLWA 4JZBA 3RYEA 4P0WA 4F6VA 4EA1A 4RNQA 3KRAB 2Q58A 1UBVA 3KROB 3WCCA 3NPKA 3WJOA 5JV1F 3WCFA 2J1PA 3ACXA 1YHKA 4DEMF 3M00A 1HXAA 4OKZA 3WE9A 1V4EA 4EA0A 1DI1A 3N5HF 3WSAA 5HN9A 2E8WA 4GAXA 3M02A 4E9UA 4GP2A 4KFAA 4KVWA 3G4FA 3PYBA 3WEGA 1KIYA 3EGTA 4LFGA 2Z78A 5ILKA 4Q23A 4E9ZA 5A0JA 3S9VA 5B02A 3BNYA 4QPFA 5AELA 3ASXA 3WEHA 3WCHA 4KUXA 4LFEA 4FJQA 1V4HA 4LZ3A 3AQCB 3PDEA 4H5EF 4DWBA 2E8UA 4H5DF 3LVSA 1YJ4A 3ZMBA 5ILHA 2ZCSA 3LGZB 1DGPA 3DYGA 3AQBB 4KVYA 3ZMCA 3LG5A 4KQSA 3SDRA 5EROA 3LZ9A 4F6XA 3V66A 3Q30A 2ZCOA 3KROA 4LTVA 2PS6A 4LLTA 1WL0A 1N21A 2ZCQA 5B00A 3N6KF 4DWGA 5IVGA 3LEEA 3UCAA 4JYXA 3ZCDA 4GP1A 1WMWA 1N1ZA 2ONHA 1RTRA 2OPNA 2Z4VA 2Q9ZA 1HM4A 4N1ZF 5JV0F 5ILYA 2AETA 3EFQA 3ID0A 2F92F 5DW7A 3P5RA 3M0GA 3ICMA 4OKMA 5AHUB 5EATA 5DHIA 1HXGA 5DJPF 3WJKA 3WCIA 3N0FA 3WCMA 1UBWA 4E1EA 3P41A 3OABB 3VJBA 3CP6A 2F8CF 3N0GA 4KPDA 3IBAA 3P8LA 1V4IA 5DGMF 3WEJA 2Z7HA 3M01A 5IN8A 3LSNA 5IK6A 5DJVF 1KIZA 2F9KF 3EZ3A 5B03A 5IL3A 4KVIA 1V4KA 2EWGA 1JFAA 5IL8A 3VJCA 2QISA 5HNAA 3QQVA 5E8HA 3RBMA 2OA6A 3P5PA 1YHLA 2ZCRA 4H5CF 4RYPA 3AE0A 3KRCA 3TFNA 4NFKF 2E4OA 3CKEA 2Q9YA 3SDUA 3ZOUA 2E8XA 2PS5A 4RXAA 3DYFA 1V4JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NPR A;  5IKA A;  5IMP A;  4LIX A;  3ICK A;  4JXY A;  4ZQ8 A;  5B0J A;  1YYQ A;  3ACY A;  4MC3 A;  4NKF A;  4NUA A;  1WY0 A;  1VG2 A;  3LK5 A;  2E93 A;  3LDW A;  5ER8 A;  5B0K A;  2F94 F;  3NRI A;  4LTZ A;  2F89 F;  2VF6 A;  2OPM A;  2E90 A;  2ONG A;  3OAB A;  4DZW A;  1PS1 A;  4WK5 A;  3N45 F;  4KPJ A;  5KSX F;  4KQU A;  1VG3 A;  4LPG F;  3WCG A;  4N9U A;  3N5J F;  3Q2Q A;  5IMI A;  4NFJ F;  2ZY1 A;  3ICZ A;  5JA0 F;  3APZ A;  4OMG A;  4NG6 A;  2Z4W A;  2E92 A;  2ZEV A;  1UBX A;  3KRP A;  2AEK A;  4OMH A;  1N20 A;  3N3L F;  3KRC B;  4L2X F;  3RMG A;  5DGN F;  4LFV F;  4P0V A;  4NKE A;  3N1V F;  1N24 A;  3TFV A;  5JV2 F;  3WCL A;  3KBK A;  3V1X A;  5AFX A;  4PVY F;  4KK2 A;  5B0I A;  3WCJ A;  5ILD A;  1VG6 A;  2PS8 A;  3M9U A;  3BNX A;  1YYS A;  5B0L A;  4KVD A;  3TFP A;  3S4J A;  1UBY A;  4LZ0 A;  4EA2 A;  3WCD A;  3N49 F;  3QKC A;  1HXC A;  2F7M F;  2Z7I A;  3N1W F;  3NF2 A;  5B0M A;  5JUZ F;  4LA5 A;  1WL1 A;  3WEK A;  5CG6 A;  3KRF B;  4GA3 A;  1YV5 A;  3CC9 A;  3WCA A;  4XQS F;  4XQR F;  3MZV A;  4LUU A;  3ACW A;  3Q2Z A;  1N1B A;  3Q1O A;  3N3D A;  3KRP B;  2Z4Y A;  5I1U A;  5A0I A;  2PS7 A;  3ICN A;  4LOB A;  1YYT A;  3TC1 A;  3LMD A;  5C05 A;  3TS7 A;  2AZL A;  1WL3 A;  3WJN A;  4OGU A;  2E94 A;  3ZL6 A;  5ERM A;  3W7F A;  5DIQ F;  3SAE A;  4LA6 A;  1VG7 A;  2I19 A;  3LJI A;  3WEF A;  4NFI F;  4DI5 A;  4FP4 A;  2FTZ A;  3AQ0 A;  3RYW A;  2FOR A;  3G4D A;  4P0X A;  2Q80 A;  3OAC A;  4JZX A;  5ILI A;  4KKM A;  1RQJ A;  4RXD A;  2ZEU A;  5IMN A;  1YYU A;  4KWD A;  2DH4 A;  5HN8 A;  3VJ9 A;  4DHD A;  5E8L A;  4PVX F;  5E8K A;  4LXW A;  4HD1 A;  3VJ8 A;  3SDQ A;  2H8O A;  4RXC A;  3KRF A;  3DYH A;  5ILZ A;  3P8R A;  4JVJ F;  2E91 A;  2P1C A;  5IKH A;  3WCB A;  2E8T A;  1EZF A;  5DZ2 A;  3SDV A;  1VG4 A;  3PKO A;  4MC8 A;  2E95 A;  2Z4X A;  4LPH F;  4RXE A;  1ZW5 A;  5EAU A;  3PYA A;  3SDT A;  1FPS A;  5ILJ A;  3MAV A;  2AZJ A;  3ADZ A;  1HM7 A;  1WKZ A;  4LZC A;  3N46 F;  3VJE A;  4XQT F;  2J5C A;  3KRA A;  3LGK A;  4UMJ A;  5IM1 A;  3PH7 A;  1YQ7 A;  3WCE A;  2AEL A;  5DGS F;  3OAC B;  3KB9 A;  1YHM A;  4DXJ A;  2Z50 A;  1HX9 A;  5DJR F;  5IK0 A;  2J1O A;  2RAH A;  1WL2 A;  2O1O A;  4QXS F;  5B01 A;  2Z52 A;  4K10 A;  2E8V A;  5A0K A;  4MC0 A;  1YYR A;  5ERN A;  2AZK A;  3VJD A;  3B7L A;  5AYP A;  1RQI A;  1N22 A;  2PS4 A;  2OGD A;  4KQ5 A;  5DHK A;  2F8Z F;  3LOM A;  3V1V A;  3VJA A;  5CG5 A;  5H9D A;  5HN7 A;  3WC9 A;  2Z4Z A;  4F62 A;  4LLS A;  3WSB A;  3OYR A;  4JXN A;  5EAS A;  3WEI A;  1JFG A;  3IPI A;  1N23 A;  5IK9 A;  3LLW A;  4JZB A;  3RYE A;  4P0W A;  4F6V A;  4EA1 A;  4RNQ A;  3KRA B;  2Q58 A;  1UBV A;  3KRO B;  3WCC A;  3NPK A;  3WJO A;  5JV1 F;  3WCF A;  2J1P A;  3ACX A;  1YHK A;  4DEM F;  3M00 A;  1HXA A;  4OKZ A;  3WE9 A;  1V4E A;  4EA0 A;  1DI1 A;  3N5H F;  3WSA A;  5HN9 A;  2E8W A;  4GAX A;  3M02 A;  4E9U A;  4GP2 A;  4KFA A;  4KVW A;  3G4F A;  3PYB A;  3WEG A;  1KIY A;  3EGT A;  4LFG A;  2Z78 A;  5ILK A;  4Q23 A;  4E9Z A;  5A0J A;  3S9V A;  5B02 A;  3BNY A;  4QPF A;  5AEL A;  3ASX A;  3WEH A;  3WCH A;  4KUX A;  4LFE A;  4FJQ A;  1V4H A;  4LZ3 A;  3AQC B;  3PDE A;  4H5E F;  4DWB A;  2E8U A;  4H5D F;  3LVS A;  1YJ4 A;  3ZMB A;  5ILH A;  2ZCS A;  3LGZ B;  1DGP A;  3DYG A;  3AQB B;  4KVY A;  3ZMC A;  3LG5 A;  4KQS A;  3SDR A;  5ERO A;  3LZ9 A;  4F6X A;  3V66 A;  3Q30 A;  2ZCO A;  3KRO A;  4LTV A;  2PS6 A;  4LLT A;  1WL0 A;  1N21 A;  2ZCQ A;  5B00 A;  3N6K F;  4DWG A;  5IVG A;  3LEE A;  3UCA A;  4JYX A;  3ZCD A;  4GP1 A;  1WMW A;  1N1Z A;  2ONH A;  1RTR A;  2OPN A;  2Z4V A;  2Q9Z A;  1HM4 A;  4N1Z F;  5JV0 F;  5ILY A;  2AET A;  3EFQ A;  3ID0 A;  2F92 F;  5DW7 A;  3P5R A;  3M0G A;  3ICM A;  4OKM A;  5AHU B;  5EAT A;  5DHI A;  1HXG A;  5DJP F;  3WJK A;  3WCI A;  3N0F A;  3WCM A;  1UBW A;  4E1E A;  3P41 A;  3OAB B;  3VJB A;  3CP6 A;  2F8C F;  3N0G A;  4KPD A;  3IBA A;  3P8L A;  1V4I A;  5DGM F;  3WEJ A;  2Z7H A;  3M01 A;  5IN8 A;  3LSN A;  5IK6 A;  5DJV F;  1KIZ A;  2F9K F;  3EZ3 A;  5B03 A;  5IL3 A;  4KVI A;  1V4K A;  2EWG A;  1JFA A;  5IL8 A;  3VJC A;  2QIS A;  5HNA A;  3QQV A;  5E8H A;  3RBM A;  2OA6 A;  3P5P A;  1YHL A;  2ZCR A;  4H5C F;  4RYP A;  3AE0 A;  3KRC A;  3TFN A;  4NFK F;  2E4O A;  3CKE A;  2Q9Y A;  3SDU A;  3ZOU A;  2E8X A;  2PS5 A;  4RXA A;  3DYF A;  1V4J A; 
#chains in the Genus database with same CATH topology
 3NPR A;  5IKA A;  5IMP A;  4LIX A;  3ICK A;  4JXY A;  4ZQ8 A;  5B0J A;  1YYQ A;  3ACY A;  4MC3 A;  4NKF A;  4NUA A;  1WY0 A;  1VG2 A;  3LK5 A;  2E93 A;  3LDW A;  5ER8 A;  5B0K A;  2F94 F;  3NRI A;  4LTZ A;  2F89 F;  2VF6 A;  2OPM A;  2E90 A;  2ONG A;  3OAB A;  4DZW A;  1PS1 A;  4WK5 A;  3N45 F;  4KPJ A;  5KSX F;  4KQU A;  1VG3 A;  4LPG F;  3WCG A;  4N9U A;  3N5J F;  3Q2Q A;  5IMI A;  4NFJ F;  2ZY1 A;  3ICZ A;  5JA0 F;  3APZ A;  4OMG A;  4NG6 A;  2Z4W A;  2E92 A;  2ZEV A;  1UBX A;  3KRP A;  2AEK A;  4OMH A;  1N20 A;  3N3L F;  3KRC B;  4L2X F;  3RMG A;  5DGN F;  4LFV F;  4P0V A;  4NKE A;  3N1V F;  1N24 A;  3TFV A;  5JV2 F;  3WCL A;  3KBK A;  3V1X A;  5AFX A;  4PVY F;  4KK2 A;  5B0I A;  3WCJ A;  5ILD A;  1VG6 A;  2PS8 A;  3M9U A;  3BNX A;  1YYS A;  5B0L A;  4KVD A;  3TFP A;  3S4J A;  1UBY A;  4LZ0 A;  4EA2 A;  3WCD A;  3N49 F;  3QKC A;  1HXC A;  2F7M F;  2Z7I A;  3N1W F;  3NF2 A;  5B0M A;  5JUZ F;  4LA5 A;  1WL1 A;  3WEK A;  5CG6 A;  3KRF B;  4GA3 A;  1YV5 A;  3CC9 A;  3WCA A;  4XQS F;  4XQR F;  3MZV A;  4LUU A;  3ACW A;  3Q2Z A;  1N1B A;  3Q1O A;  3N3D A;  3KRP B;  2Z4Y A;  5I1U A;  5A0I A;  2PS7 A;  3ICN A;  4LOB A;  1YYT A;  3TC1 A;  3LMD A;  5C05 A;  3TS7 A;  2AZL A;  1WL3 A;  3WJN A;  4OGU A;  2E94 A;  3ZL6 A;  5ERM A;  3W7F A;  5DIQ F;  3SAE A;  4LA6 A;  1VG7 A;  2I19 A;  3LJI A;  3WEF A;  4NFI F;  4DI5 A;  4FP4 A;  2FTZ A;  3AQ0 A;  3RYW A;  2FOR A;  3G4D A;  4P0X A;  2Q80 A;  3OAC A;  4JZX A;  5ILI A;  4KKM A;  1RQJ A;  4RXD A;  2ZEU A;  5IMN A;  1YYU A;  4KWD A;  2DH4 A;  5HN8 A;  3VJ9 A;  4DHD A;  5E8L A;  4PVX F;  5E8K A;  4LXW A;  4HD1 A;  3VJ8 A;  3SDQ A;  2H8O A;  4RXC A;  3KRF A;  3DYH A;  5ILZ A;  3P8R A;  4JVJ F;  2E91 A;  2P1C A;  5IKH A;  3WCB A;  2E8T A;  1EZF A;  5DZ2 A;  3SDV A;  1VG4 A;  3PKO A;  4MC8 A;  2E95 A;  2Z4X A;  4LPH F;  4RXE A;  1ZW5 A;  5EAU A;  3PYA A;  3SDT A;  1FPS A;  5ILJ A;  3MAV A;  2AZJ A;  3ADZ A;  1HM7 A;  1WKZ A;  4LZC A;  3N46 F;  3VJE A;  4XQT F;  2J5C A;  3KRA A;  3LGK A;  4UMJ A;  5IM1 A;  3PH7 A;  1YQ7 A;  3WCE A;  2AEL A;  5DGS F;  3OAC B;  3KB9 A;  1YHM A;  4DXJ A;  2Z50 A;  1HX9 A;  5DJR F;  5IK0 A;  2J1O A;  2RAH A;  1WL2 A;  2O1O A;  4QXS F;  5B01 A;  2Z52 A;  4K10 A;  2E8V A;  5A0K A;  4MC0 A;  1YYR A;  5ERN A;  2AZK A;  3VJD A;  3B7L A;  5AYP A;  1RQI A;  1N22 A;  2PS4 A;  2OGD A;  4KQ5 A;  5DHK A;  2F8Z F;  3LOM A;  3V1V A;  3VJA A;  5CG5 A;  5H9D A;  5HN7 A;  3WC9 A;  2Z4Z A;  4F62 A;  4LLS A;  3WSB A;  3OYR A;  4JXN A;  5EAS A;  3WEI A;  1JFG A;  3IPI A;  1N23 A;  5IK9 A;  3LLW A;  4JZB A;  3RYE A;  4P0W A;  4F6V A;  4EA1 A;  4RNQ A;  3KRA B;  2Q58 A;  1UBV A;  3KRO B;  3WCC A;  3NPK A;  3WJO A;  5JV1 F;  3WCF A;  2J1P A;  3ACX A;  1YHK A;  4DEM F;  3M00 A;  1HXA A;  4OKZ A;  3WE9 A;  1V4E A;  4EA0 A;  1DI1 A;  3N5H F;  3WSA A;  5HN9 A;  2E8W A;  4GAX A;  3M02 A;  4E9U A;  4GP2 A;  4KFA A;  4KVW A;  3G4F A;  3PYB A;  3WEG A;  1KIY A;  3EGT A;  4LFG A;  2Z78 A;  5ILK A;  4Q23 A;  4E9Z A;  5A0J A;  3S9V A;  5B02 A;  3BNY A;  4QPF A;  5AEL A;  3ASX A;  3WEH A;  3WCH A;  4KUX A;  4LFE A;  4FJQ A;  1V4H A;  4LZ3 A;  3AQC B;  3PDE A;  4H5E F;  4DWB A;  2E8U A;  4H5D F;  3LVS A;  1YJ4 A;  3ZMB A;  5ILH A;  2ZCS A;  3LGZ B;  1DGP A;  3DYG A;  3AQB B;  4KVY A;  3ZMC A;  3LG5 A;  4KQS A;  3SDR A;  5ERO A;  3LZ9 A;  4F6X A;  3V66 A;  3Q30 A;  2ZCO A;  3KRO A;  4LTV A;  2PS6 A;  4LLT A;  1WL0 A;  1N21 A;  2ZCQ A;  5B00 A;  3N6K F;  4DWG A;  5IVG A;  3LEE A;  3UCA A;  4JYX A;  3ZCD A;  4GP1 A;  1WMW A;  1N1Z A;  2ONH A;  1RTR A;  2OPN A;  2Z4V A;  2Q9Z A;  1HM4 A;  4N1Z F;  5JV0 F;  5ILY A;  2AET A;  3EFQ A;  3ID0 A;  2F92 F;  5DW7 A;  3P5R A;  3M0G A;  3ICM A;  4OKM A;  5AHU B;  5EAT A;  5DHI A;  1HXG A;  5DJP F;  3WJK A;  3WCI A;  3N0F A;  3WCM A;  1UBW A;  4E1E A;  3P41 A;  3OAB B;  3VJB A;  3CP6 A;  2F8C F;  3N0G A;  4KPD A;  3IBA A;  3P8L A;  1V4I A;  5DGM F;  3WEJ A;  2Z7H A;  3M01 A;  5IN8 A;  3LSN A;  5IK6 A;  5DJV F;  1KIZ A;  2F9K F;  3EZ3 A;  5B03 A;  5IL3 A;  4KVI A;  1V4K A;  2EWG A;  1JFA A;  5IL8 A;  3VJC A;  2QIS A;  5HNA A;  3QQV A;  5E8H A;  3RBM A;  2OA6 A;  3P5P A;  1YHL A;  2ZCR A;  4H5C F;  4RYP A;  3AE0 A;  3KRC A;  3TFN A;  4NFK F;  2E4O A;  3CKE A;  2Q9Y A;  3SDU A;  3ZOU A;  2E8X A;  2PS5 A;  4RXA A;  3DYF A;  1V4J A; 
#chains in the Genus database with same CATH homology
 3NPR A;  5IKA A;  5IMP A;  4LIX A;  3ICK A;  4JXY A;  4ZQ8 A;  5B0J A;  1YYQ A;  3ACY A;  4MC3 A;  4NKF A;  4NUA A;  1WY0 A;  1VG2 A;  3LK5 A;  2E93 A;  3LDW A;  5ER8 A;  5B0K A;  2F94 F;  3NRI A;  4LTZ A;  2F89 F;  2VF6 A;  2OPM A;  2E90 A;  2ONG A;  3OAB A;  4DZW A;  1PS1 A;  4WK5 A;  3N45 F;  4KPJ A;  5KSX F;  4KQU A;  1VG3 A;  4LPG F;  3WCG A;  4N9U A;  3N5J F;  3Q2Q A;  5IMI A;  4NFJ F;  2ZY1 A;  3ICZ A;  5JA0 F;  3APZ A;  4OMG A;  4NG6 A;  2Z4W A;  2E92 A;  2ZEV A;  1UBX A;  3KRP A;  2AEK A;  4OMH A;  1N20 A;  3N3L F;  3KRC B;  4L2X F;  3RMG A;  5DGN F;  4LFV F;  4P0V A;  4NKE A;  3N1V F;  1N24 A;  3TFV A;  5JV2 F;  3WCL A;  3KBK A;  3V1X A;  5AFX A;  4PVY F;  4KK2 A;  5B0I A;  3WCJ A;  5ILD A;  1VG6 A;  2PS8 A;  3M9U A;  3BNX A;  1YYS A;  5B0L A;  4KVD A;  3TFP A;  3S4J A;  1UBY A;  4LZ0 A;  4EA2 A;  3WCD A;  3N49 F;  3QKC A;  1HXC A;  2F7M F;  2Z7I A;  3N1W F;  3NF2 A;  5B0M A;  5JUZ F;  4LA5 A;  1WL1 A;  3WEK A;  5CG6 A;  3KRF B;  4GA3 A;  1YV5 A;  3CC9 A;  3WCA A;  4XQS F;  4XQR F;  3MZV A;  4LUU A;  3ACW A;  3Q2Z A;  1N1B A;  3Q1O A;  3N3D A;  3KRP B;  2Z4Y A;  5I1U A;  5A0I A;  2PS7 A;  3ICN A;  4LOB A;  1YYT A;  3TC1 A;  3LMD A;  5C05 A;  3TS7 A;  2AZL A;  1WL3 A;  3WJN A;  4OGU A;  2E94 A;  3ZL6 A;  5ERM A;  3W7F A;  5DIQ F;  3SAE A;  4LA6 A;  1VG7 A;  2I19 A;  3LJI A;  3WEF A;  4NFI F;  4DI5 A;  4FP4 A;  2FTZ A;  3AQ0 A;  3RYW A;  2FOR A;  3G4D A;  4P0X A;  2Q80 A;  3OAC A;  4JZX A;  5ILI A;  4KKM A;  1RQJ A;  4RXD A;  2ZEU A;  5IMN A;  1YYU A;  4KWD A;  2DH4 A;  5HN8 A;  3VJ9 A;  4DHD A;  5E8L A;  4PVX F;  5E8K A;  4LXW A;  4HD1 A;  3VJ8 A;  3SDQ A;  2H8O A;  4RXC A;  3KRF A;  3DYH A;  5ILZ A;  3P8R A;  4JVJ F;  2E91 A;  2P1C A;  5IKH A;  3WCB A;  2E8T A;  1EZF A;  5DZ2 A;  3SDV A;  1VG4 A;  3PKO A;  4MC8 A;  2E95 A;  2Z4X A;  4LPH F;  4RXE A;  1ZW5 A;  5EAU A;  3PYA A;  3SDT A;  1FPS A;  5ILJ A;  3MAV A;  2AZJ A;  3ADZ A;  1HM7 A;  1WKZ A;  4LZC A;  3N46 F;  3VJE A;  4XQT F;  2J5C A;  3KRA A;  3LGK A;  4UMJ A;  5IM1 A;  3PH7 A;  1YQ7 A;  3WCE A;  2AEL A;  5DGS F;  3OAC B;  3KB9 A;  1YHM A;  4DXJ A;  2Z50 A;  1HX9 A;  5DJR F;  5IK0 A;  2J1O A;  2RAH A;  1WL2 A;  2O1O A;  4QXS F;  5B01 A;  2Z52 A;  4K10 A;  2E8V A;  5A0K A;  4MC0 A;  1YYR A;  5ERN A;  2AZK A;  3VJD A;  3B7L A;  5AYP A;  1RQI A;  1N22 A;  2PS4 A;  2OGD A;  4KQ5 A;  5DHK A;  2F8Z F;  3LOM A;  3V1V A;  3VJA A;  5CG5 A;  5H9D A;  5HN7 A;  3WC9 A;  2Z4Z A;  4F62 A;  4LLS A;  3WSB A;  3OYR A;  4JXN A;  5EAS A;  3WEI A;  1JFG A;  3IPI A;  1N23 A;  5IK9 A;  3LLW A;  4JZB A;  3RYE A;  4P0W A;  4F6V A;  4EA1 A;  4RNQ A;  3KRA B;  2Q58 A;  1UBV A;  3KRO B;  3WCC A;  3NPK A;  3WJO A;  5JV1 F;  3WCF A;  2J1P A;  3ACX A;  1YHK A;  4DEM F;  3M00 A;  1HXA A;  4OKZ A;  3WE9 A;  1V4E A;  4EA0 A;  1DI1 A;  3N5H F;  3WSA A;  5HN9 A;  2E8W A;  4GAX A;  3M02 A;  4E9U A;  4GP2 A;  4KFA A;  4KVW A;  3G4F A;  3PYB A;  3WEG A;  1KIY A;  3EGT A;  4LFG A;  2Z78 A;  5ILK A;  4Q23 A;  4E9Z A;  5A0J A;  3S9V A;  5B02 A;  3BNY A;  4QPF A;  5AEL A;  3ASX A;  3WEH A;  3WCH A;  4KUX A;  4LFE A;  4FJQ A;  1V4H A;  4LZ3 A;  3AQC B;  3PDE A;  4H5E F;  4DWB A;  2E8U A;  4H5D F;  3LVS A;  1YJ4 A;  3ZMB A;  5ILH A;  2ZCS A;  3LGZ B;  1DGP A;  3DYG A;  3AQB B;  4KVY A;  3ZMC A;  3LG5 A;  4KQS A;  3SDR A;  5ERO A;  3LZ9 A;  4F6X A;  3V66 A;  3Q30 A;  2ZCO A;  3KRO A;  4LTV A;  2PS6 A;  4LLT A;  1WL0 A;  1N21 A;  2ZCQ A;  5B00 A;  3N6K F;  4DWG A;  5IVG A;  3LEE A;  3UCA A;  4JYX A;  3ZCD A;  4GP1 A;  1WMW A;  1N1Z A;  2ONH A;  1RTR A;  2OPN A;  2Z4V A;  2Q9Z A;  1HM4 A;  4N1Z F;  5JV0 F;  5ILY A;  2AET A;  3EFQ A;  3ID0 A;  2F92 F;  5DW7 A;  3P5R A;  3M0G A;  3ICM A;  4OKM A;  5AHU B;  5EAT A;  5DHI A;  1HXG A;  5DJP F;  3WJK A;  3WCI A;  3N0F A;  3WCM A;  1UBW A;  4E1E A;  3P41 A;  3OAB B;  3VJB A;  3CP6 A;  2F8C F;  3N0G A;  4KPD A;  3IBA A;  3P8L A;  1V4I A;  5DGM F;  3WEJ A;  2Z7H A;  3M01 A;  5IN8 A;  3LSN A;  5IK6 A;  5DJV F;  1KIZ A;  2F9K F;  3EZ3 A;  5B03 A;  5IL3 A;  4KVI A;  1V4K A;  2EWG A;  1JFA A;  5IL8 A;  3VJC A;  2QIS A;  5HNA A;  3QQV A;  5E8H A;  3RBM A;  2OA6 A;  3P5P A;  1YHL A;  2ZCR A;  4H5C F;  4RYP A;  3AE0 A;  3KRC A;  3TFN A;  4NFK F;  2E4O A;  3CKE A;  2Q9Y A;  3SDU A;  3ZOU A;  2E8X A;  2PS5 A;  4RXA A;  3DYF A;  1V4J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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