4K10A

Crystal structure of leshmaniasis major farnesyl diphosphate synthase in complex with 3-fluoro-1-(2-hydroxy-2,2-diphosphonoethyl)pyridinium and mg2+
Total Genus 146
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
146
sequence length
361
structure length
358
Chain Sequence
MAHMERFQKVYEEVQEFLLGDAEKRFEMDVHRKGYLKSMMDTTCLGGKYNRGLCVVDVAEAMAKDTQMDAAAMERVLHDACVCGWMIEMLQAHFLVEDDIMDHSKTRRGKPCWYLHPGVTAQVAINDGLILLAWATQMALHYFADRPFLAEVLRVFHDVDLTTTIGQLYDVTSMVDSAKLDAKVAHANTTDYVEYTPFNHRRIVVYKTAYYTYWLPLVMGLLVSGTLEKVDKKATHKVAMVMGEYFQVQDDVMDCFTPPEKIGTDIEDAKCSWLAVTFLTTAPAEKVAEFKANYGSTDPAAVAVIKQLYTEQNLLARFEEYEKAVVAEVEQLIAALEAQNAAFAASVKVLWSKTYKRQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Farnesyl pyrophosphate synthase
publication title Structural and thermodynamic basis of the inhibition of Leishmania major farnesyl diphosphate synthase by nitrogen-containing bisphosphonates.
pubmed doi rcsb
source organism Leishmania major
molecule tags Transferase/transferase inhibitor
total genus 146
structure length 358
sequence length 361
chains with identical sequence B, C, D
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2013-04-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4k10A00
3RBMA 3WCFA 3WCEA 2ONHA 5B00A 4KVWA 2PS5A 3WSBA 4P0VA 5IN8A 3KROB 2ZY1A 3ICMA 4FP4A 4KPDA 4OKMA 4LZ3A 3PKOA 4MC8A 1YHMA 2Q9ZA 3DYGA 2ZCSA 4LZCA 3NRIA 4LPGF 3WEKA 3N5JF 3N46F 3WCLA 3EGTA 4N1ZF 3LG5A 3VJ9A 4GP1A 2E8WA 2H8OA 5ER8A 4XQTF 4P0XA 5IKAA 5HN7A 5IK6A 1N21A 4DHDA 2F7MF 3OACA 1VG7A 1N24A 2Z4ZA 4XQRF 2J1OA 3P41A 3EZ3A 3WCCA 2F8CF 5E8KA 3NF2A 3NPKA 4ZQ8A 2ONGA 1RQIA 3LDWA 3SDQA 4EA0A 4NG6A 2E8VA 3B7LA 3VJCA 3WCMA 1KIYA 5ILDA 1HX9A 1N1BA 2Z50A 5DW7A 3N3LF 4NKEA 2OPNA 1V4EA 1VG3A 5EASA 5CG5A 3SDVA 5EAUA 3MZVA 3SDUA 3VJ8A 3WCBA 1HXCA 4E9UA 2AEKA 1YV5A 4KVIA 2ZCOA 3KRCA 4KQSA 5IMIA 5JUZF 4H5DF 5B0IA 2J1PA 2Z7IA 5B0KA 3KBKA 3TFNA 3UCAA 3BNXA 4NKFA 2FTZA 3WJOA 2AZKA 1YHKA 3KRPA 1YYSA 4KWDA 4JVJF 1VG6A 4JYXA 2PS4A 4GAXA 3CC9A 3TFPA 3G4DA 3LVSA 1EZFA 5DHIA 5B0MA 4F6VA 5DIQF 3V1VA 4FJQA 3W7FA 2EWGA 1JFGA 3RYEA 3OACB 3CKEA 1WL1A 3WEGA 4JXNA 2Z78A 4KPJA 4OKZA 4KQ5A 5ILJA 5C05A 5CG6A 3WCIA 1DI1A 1N1ZA 5E8LA 3AQBB 4F62A 3RMGA 3APZA 5ERNA 4GP2A 2F89F 5IMPA 4DWBA 4LTZA 1RTRA 3M01A 4LUUA 5IVGA 4DI5A 2J5CA 3WEIA 4LA5A 1RQJA 3Q2QA 5EATA 1YYUA 2AZJA 2AZLA 4NFIF 5AYPA 3LK5A 4MC3A 2E8TA 4RYPA 3BNYA 3ZL6A 2OA6A 5B0LA 3ID0A 5B03A 1YQ7A 4NUAA 4HD1A 3KRFA 3QKCA 1HXAA 4LPHF 3ADZA 3V1XA 5AELA 4KKMA 3P8RA 5DGNF 5A0JA 5B01A 1WL0A 2Z4VA 4LFVF 5KSXF 3WJKA 4MC0A 5AFXA 3PH7A 1YYQA 5ERMA 3SDTA 5B02A 5JV2F 4OGUA 4LZ0A 4LFEA 5ILYA 3N49F 3LGZB 2QISA 4PVXF 3ASXA 2Q9YA 2E8UA 5DHKA 4KK2A 3VJAA 2ZCQA 4DXJA 3WC9A 4PVYF 3LGKA 3LMDA 5JV1F 3VJBA 4EA1A 5ILIA 3V66A 4GA3A 4KUXA 2F8ZF 3N3DA 4DWGA 5IK0A 2E8XA 4N9UA 3Q30A 1N20A 4LOBA 4Q23A 4LTVA 5HNAA 5DJPF 3VJDA 4XQSF 2O1OA 2Z4XA 4H5CF 4RXEA 3N6KF 4KVDA 3N5HF 3Q2ZA 5JV0F 2I19A 2AETA 3DYFA 4H5EF 3WCHA 4JXYA 4EA2A 2E95A 1HXGA 2F9KF 4QXSF 3LEEA 3S4JA 1WY0A 3PYBA 2Q58A 3ZMBA 2PS7A 5EROA 1N22A 3M02A 4L2XF 3WCAA 2F94F 4LFGA 1V4JA 5HN8A 2E94A 4RXDA 3KB9A 3IBAA 1YYRA 3ICKA 1ZW5A 3WSAA 4RXCA 3N45F 3N1VF 4RNQA 5ILKA 2ZEUA 4LIXA 1YHLA 2E92A 3OYRA 4KQUA 3DYHA 3WEHA 3CP6A 1UBVA 3LZ9A 3AE0A 3QQVA 5E8HA 1V4IA 3ICZA 1WL3A 1YJ4A 2Z4YA 5DJVF 3AQ0A 3N0FA 3ZOUA 1N23A 3N0GA 5ILZA 2Z52A 3P8LA 2Q80A 1VG4A 5H9DA 5DGSF 5ILHA 3KRAA 3ZCDA 2E93A 3KRCB 3M00A 4DEMF 3TFVA 4KVYA 3ZMCA 4OMGA 1WKZA 2Z7HA 5AHUB 3NPRA 3OABA 2PS8A 5B0JA 5IM1A 1VG2A 4UMJA 1FPSA 3M0GA 1WMWA 3ACXA 3MAVA 2AELA 3PDEA 3LJIA 3KRPB 2ZEVA 5IMNA 5IL3A 3VJEA 5DGMF 4NFKF 2F92F 3KROA 3AQCB 3WEFA 3TS7A 3WCDA 4LLSA 3IPIA 5I1UA 3M9UA 1YYTA 2ZCRA 1V4KA 3WCGA 3EFQA 5IKHA 4QPFA 4P0WA 1HM4A 3TC1A 3Q1OA 4F6XA 3ICNA 2FORA 1WL2A 5A0KA 3LOMA 2PS6A 3SDRA 2Z4WA 2OPMA 1DGPA 3ACWA 2OGDA 4WK5A 1KIZA 5IK9A 3LLWA 4NFJF 4DZWA 5DZ2A 3WCJA 5IL8A 3PYAA 3G4FA 5A0IA 2DH4A 4OMHA 2E90A 3N1WF 1V4HA 2RAHA 3SAEA 4LLTA 1UBXA 2VF6A 5HN9A 5JA0F 4K10A 2P1CA 4RXAA 1HM7A 2E4OA 3P5PA 1JFAA 4JZBA 3KRFB 3P5RA 3WEJA 2E91A 3KRAB 4KFAA 3S9VA 3WJNA 3LSNA 4E1EA 4JZXA 1UBYA 5DJRF 3OABB 3WE9A 1PS1A 4LXWA 1UBWA 4LA6A 3RYWA 3ACYA 4E9ZA
chains in the Genus database with same CATH superfamily
3RBMA 3WCFA 3WCEA 2ONHA 5B00A 4KVWA 2PS5A 3WSBA 4P0VA 5IN8A 3KROB 2ZY1A 3ICMA 4FP4A 4KPDA 4OKMA 4LZ3A 3PKOA 4MC8A 1YHMA 2Q9ZA 3DYGA 2ZCSA 4LZCA 3NRIA 4LPGF 3WEKA 3N5JF 3N46F 3WCLA 3EGTA 4N1ZF 3LG5A 3VJ9A 4GP1A 2E8WA 2H8OA 5ER8A 4XQTF 4P0XA 5IKAA 5HN7A 5IK6A 1N21A 4DHDA 2F7MF 3OACA 1VG7A 1N24A 2Z4ZA 4XQRF 2J1OA 3P41A 3EZ3A 3WCCA 2F8CF 5E8KA 3NF2A 3NPKA 4ZQ8A 2ONGA 1RQIA 3LDWA 3SDQA 4EA0A 4NG6A 2E8VA 3B7LA 3VJCA 3WCMA 1KIYA 5ILDA 1HX9A 1N1BA 2Z50A 5DW7A 3N3LF 4NKEA 2OPNA 1V4EA 1VG3A 5EASA 5CG5A 3SDVA 5EAUA 3MZVA 3SDUA 3VJ8A 3WCBA 1HXCA 4E9UA 2AEKA 1YV5A 4KVIA 2ZCOA 3KRCA 4KQSA 5IMIA 5JUZF 4H5DF 5B0IA 2J1PA 2Z7IA 5B0KA 3KBKA 3TFNA 3UCAA 3BNXA 4NKFA 2FTZA 3WJOA 2AZKA 1YHKA 3KRPA 1YYSA 4KWDA 4JVJF 1VG6A 4JYXA 2PS4A 4GAXA 3CC9A 3TFPA 3G4DA 3LVSA 1EZFA 5DHIA 5B0MA 4F6VA 5DIQF 3V1VA 4FJQA 3W7FA 2EWGA 1JFGA 3RYEA 3OACB 3CKEA 1WL1A 3WEGA 4JXNA 2Z78A 4KPJA 4OKZA 4KQ5A 5ILJA 5C05A 5CG6A 3WCIA 1DI1A 1N1ZA 5E8LA 3AQBB 4F62A 3RMGA 3APZA 5ERNA 4GP2A 2F89F 5IMPA 4DWBA 4LTZA 1RTRA 3M01A 4LUUA 5IVGA 4DI5A 2J5CA 3WEIA 4LA5A 1RQJA 3Q2QA 5EATA 1YYUA 2AZJA 2AZLA 4NFIF 5AYPA 3LK5A 4MC3A 2E8TA 4RYPA 3BNYA 3ZL6A 2OA6A 5B0LA 3ID0A 5B03A 1YQ7A 4NUAA 4HD1A 3KRFA 3QKCA 1HXAA 4LPHF 3ADZA 3V1XA 5AELA 4KKMA 3P8RA 5DGNF 5A0JA 5B01A 1WL0A 2Z4VA 4LFVF 5KSXF 3WJKA 4MC0A 5AFXA 3PH7A 1YYQA 5ERMA 3SDTA 5B02A 5JV2F 4OGUA 4LZ0A 4LFEA 5ILYA 3N49F 3LGZB 2QISA 4PVXF 3ASXA 2Q9YA 2E8UA 5DHKA 4KK2A 3VJAA 2ZCQA 4DXJA 3WC9A 4PVYF 3LGKA 3LMDA 5JV1F 3VJBA 4EA1A 5ILIA 3V66A 4GA3A 4KUXA 2F8ZF 3N3DA 4DWGA 5IK0A 2E8XA 4N9UA 3Q30A 1N20A 4LOBA 4Q23A 4LTVA 5HNAA 5DJPF 3VJDA 4XQSF 2O1OA 2Z4XA 4H5CF 4RXEA 3N6KF 4KVDA 3N5HF 3Q2ZA 5JV0F 2I19A 2AETA 3DYFA 4H5EF 3WCHA 4JXYA 4EA2A 2E95A 1HXGA 2F9KF 4QXSF 3LEEA 3S4JA 1WY0A 3PYBA 2Q58A 3ZMBA 2PS7A 5EROA 1N22A 3M02A 4L2XF 3WCAA 2F94F 4LFGA 1V4JA 5HN8A 2E94A 4RXDA 3KB9A 3IBAA 1YYRA 3ICKA 1ZW5A 3WSAA 4RXCA 3N45F 3N1VF 4RNQA 5ILKA 2ZEUA 4LIXA 1YHLA 2E92A 3OYRA 4KQUA 3DYHA 3WEHA 3CP6A 1UBVA 3LZ9A 3AE0A 3QQVA 5E8HA 1V4IA 3ICZA 1WL3A 1YJ4A 2Z4YA 5DJVF 3AQ0A 3N0FA 3ZOUA 1N23A 3N0GA 5ILZA 2Z52A 3P8LA 2Q80A 1VG4A 5H9DA 5DGSF 5ILHA 3KRAA 3ZCDA 2E93A 3KRCB 3M00A 4DEMF 3TFVA 4KVYA 3ZMCA 4OMGA 1WKZA 2Z7HA 5AHUB 3NPRA 3OABA 2PS8A 5B0JA 5IM1A 1VG2A 4UMJA 1FPSA 3M0GA 1WMWA 3ACXA 3MAVA 2AELA 3PDEA 3LJIA 3KRPB 2ZEVA 5IMNA 5IL3A 3VJEA 5DGMF 4NFKF 2F92F 3KROA 3AQCB 3WEFA 3TS7A 3WCDA 4LLSA 3IPIA 5I1UA 3M9UA 1YYTA 2ZCRA 1V4KA 3WCGA 3EFQA 5IKHA 4QPFA 4P0WA 1HM4A 3TC1A 3Q1OA 4F6XA 3ICNA 2FORA 1WL2A 5A0KA 3LOMA 2PS6A 3SDRA 2Z4WA 2OPMA 1DGPA 3ACWA 2OGDA 4WK5A 1KIZA 5IK9A 3LLWA 4NFJF 4DZWA 5DZ2A 3WCJA 5IL8A 3PYAA 3G4FA 5A0IA 2DH4A 4OMHA 2E90A 3N1WF 1V4HA 2RAHA 3SAEA 4LLTA 1UBXA 2VF6A 5HN9A 5JA0F 4K10A 2P1CA 4RXAA 1HM7A 2E4OA 3P5PA 1JFAA 4JZBA 3KRFB 3P5RA 3WEJA 2E91A 3KRAB 4KFAA 3S9VA 3WJNA 3LSNA 4E1EA 4JZXA 1UBYA 5DJRF 3OABB 3WE9A 1PS1A 4LXWA 1UBWA 4LA6A 3RYWA 3ACYA 4E9ZA
chains in the Genus database with same CATH topology
3RBMA 3WCFA 3WCEA 2ONHA 5B00A 4KVWA 2PS5A 3WSBA 4P0VA 5IN8A 3KROB 2ZY1A 3ICMA 4FP4A 4KPDA 4OKMA 4LZ3A 3PKOA 4MC8A 1YHMA 2Q9ZA 3DYGA 2ZCSA 4LZCA 3NRIA 4LPGF 3WEKA 3N5JF 3N46F 3WCLA 3EGTA 4N1ZF 3LG5A 3VJ9A 4GP1A 2E8WA 2H8OA 5ER8A 4XQTF 4P0XA 5IKAA 5HN7A 5IK6A 1N21A 4DHDA 2F7MF 3OACA 1VG7A 1N24A 2Z4ZA 4XQRF 2J1OA 3P41A 3EZ3A 3WCCA 2F8CF 5E8KA 3NF2A 3NPKA 4ZQ8A 2ONGA 1RQIA 3LDWA 3SDQA 4EA0A 4NG6A 2E8VA 3B7LA 3VJCA 3WCMA 1KIYA 5ILDA 1HX9A 1N1BA 2Z50A 5DW7A 3N3LF 4NKEA 2OPNA 1V4EA 1VG3A 5EASA 5CG5A 3SDVA 5EAUA 3MZVA 3SDUA 3VJ8A 3WCBA 1HXCA 4E9UA 2AEKA 1YV5A 4KVIA 2ZCOA 3KRCA 4KQSA 5IMIA 5JUZF 4H5DF 5B0IA 2J1PA 2Z7IA 5B0KA 3KBKA 3TFNA 3UCAA 3BNXA 4NKFA 2FTZA 3WJOA 2AZKA 1YHKA 3KRPA 1YYSA 4KWDA 4JVJF 1VG6A 4JYXA 2PS4A 4GAXA 3CC9A 3TFPA 3G4DA 3LVSA 1EZFA 5DHIA 5B0MA 4F6VA 5DIQF 3V1VA 4FJQA 3W7FA 2EWGA 1JFGA 3RYEA 3OACB 3CKEA 1WL1A 3WEGA 4JXNA 2Z78A 4KPJA 4OKZA 4KQ5A 5ILJA 5C05A 5CG6A 3WCIA 1DI1A 1N1ZA 5E8LA 3AQBB 4F62A 3RMGA 3APZA 5ERNA 4GP2A 2F89F 5IMPA 4DWBA 4LTZA 1RTRA 3M01A 4LUUA 5IVGA 4DI5A 2J5CA 3WEIA 4LA5A 1RQJA 3Q2QA 5EATA 1YYUA 2AZJA 2AZLA 4NFIF 5AYPA 3LK5A 4MC3A 2E8TA 4RYPA 3BNYA 3ZL6A 2OA6A 5B0LA 3ID0A 5B03A 1YQ7A 4NUAA 4HD1A 3KRFA 3QKCA 1HXAA 4LPHF 3ADZA 3V1XA 5AELA 4KKMA 3P8RA 5DGNF 5A0JA 5B01A 1WL0A 2Z4VA 4LFVF 5KSXF 3WJKA 4MC0A 5AFXA 3PH7A 1YYQA 5ERMA 3SDTA 5B02A 5JV2F 4OGUA 4LZ0A 4LFEA 5ILYA 3N49F 3LGZB 2QISA 4PVXF 3ASXA 2Q9YA 2E8UA 5DHKA 4KK2A 3VJAA 2ZCQA 4DXJA 3WC9A 4PVYF 3LGKA 3LMDA 5JV1F 3VJBA 4EA1A 5ILIA 3V66A 4GA3A 4KUXA 2F8ZF 3N3DA 4DWGA 5IK0A 2E8XA 4N9UA 3Q30A 1N20A 4LOBA 4Q23A 4LTVA 5HNAA 5DJPF 3VJDA 4XQSF 2O1OA 2Z4XA 4H5CF 4RXEA 3N6KF 4KVDA 3N5HF 3Q2ZA 5JV0F 2I19A 2AETA 3DYFA 4H5EF 3WCHA 4JXYA 4EA2A 2E95A 1HXGA 2F9KF 4QXSF 3LEEA 3S4JA 1WY0A 3PYBA 2Q58A 3ZMBA 2PS7A 5EROA 1N22A 3M02A 4L2XF 3WCAA 2F94F 4LFGA 1V4JA 5HN8A 2E94A 4RXDA 3KB9A 3IBAA 1YYRA 3ICKA 1ZW5A 3WSAA 4RXCA 3N45F 3N1VF 4RNQA 5ILKA 2ZEUA 4LIXA 1YHLA 2E92A 3OYRA 4KQUA 3DYHA 3WEHA 3CP6A 1UBVA 3LZ9A 3AE0A 3QQVA 5E8HA 1V4IA 3ICZA 1WL3A 1YJ4A 2Z4YA 5DJVF 3AQ0A 3N0FA 3ZOUA 1N23A 3N0GA 5ILZA 2Z52A 3P8LA 2Q80A 1VG4A 5H9DA 5DGSF 5ILHA 3KRAA 3ZCDA 2E93A 3KRCB 3M00A 4DEMF 3TFVA 4KVYA 3ZMCA 4OMGA 1WKZA 2Z7HA 5AHUB 3NPRA 3OABA 2PS8A 5B0JA 5IM1A 1VG2A 4UMJA 1FPSA 3M0GA 1WMWA 3ACXA 3MAVA 2AELA 3PDEA 3LJIA 3KRPB 2ZEVA 5IMNA 5IL3A 3VJEA 5DGMF 4NFKF 2F92F 3KROA 3AQCB 3WEFA 3TS7A 3WCDA 4LLSA 3IPIA 5I1UA 3M9UA 1YYTA 2ZCRA 1V4KA 3WCGA 3EFQA 5IKHA 4QPFA 4P0WA 1HM4A 3TC1A 3Q1OA 4F6XA 3ICNA 2FORA 1WL2A 5A0KA 3LOMA 2PS6A 3SDRA 2Z4WA 2OPMA 1DGPA 3ACWA 2OGDA 4WK5A 1KIZA 5IK9A 3LLWA 4NFJF 4DZWA 5DZ2A 3WCJA 5IL8A 3PYAA 3G4FA 5A0IA 2DH4A 4OMHA 2E90A 3N1WF 1V4HA 2RAHA 3SAEA 4LLTA 1UBXA 2VF6A 5HN9A 5JA0F 4K10A 2P1CA 4RXAA 1HM7A 2E4OA 3P5PA 1JFAA 4JZBA 3KRFB 3P5RA 3WEJA 2E91A 3KRAB 4KFAA 3S9VA 3WJNA 3LSNA 4E1EA 4JZXA 1UBYA 5DJRF 3OABB 3WE9A 1PS1A 4LXWA 1UBWA 4LA6A 3RYWA 3ACYA 4E9ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RBM A;  3WCF A;  3WCE A;  2ONH A;  5B00 A;  4KVW A;  2PS5 A;  3WSB A;  4P0V A;  5IN8 A;  3KRO B;  2ZY1 A;  3ICM A;  4FP4 A;  4KPD A;  4OKM A;  4LZ3 A;  3PKO A;  4MC8 A;  1YHM A;  2Q9Z A;  3DYG A;  2ZCS A;  4LZC A;  3NRI A;  4LPG F;  3WEK A;  3N5J F;  3N46 F;  3WCL A;  3EGT A;  4N1Z F;  3LG5 A;  3VJ9 A;  4GP1 A;  2E8W A;  2H8O A;  5ER8 A;  4XQT F;  4P0X A;  5IKA A;  5HN7 A;  5IK6 A;  1N21 A;  4DHD A;  2F7M F;  3OAC A;  1VG7 A;  1N24 A;  2Z4Z A;  4XQR F;  2J1O A;  3P41 A;  3EZ3 A;  3WCC A;  2F8C F;  5E8K A;  3NF2 A;  3NPK A;  4ZQ8 A;  2ONG A;  1RQI A;  3LDW A;  3SDQ A;  4EA0 A;  4NG6 A;  2E8V A;  3B7L A;  3VJC A;  3WCM A;  1KIY A;  5ILD A;  1HX9 A;  1N1B A;  2Z50 A;  5DW7 A;  3N3L F;  4NKE A;  2OPN A;  1V4E A;  1VG3 A;  5EAS A;  5CG5 A;  3SDV A;  5EAU A;  3MZV A;  3SDU A;  3VJ8 A;  3WCB A;  1HXC A;  4E9U A;  2AEK A;  1YV5 A;  4KVI A;  2ZCO A;  3KRC A;  4KQS A;  5IMI A;  5JUZ F;  4H5D F;  5B0I A;  2J1P A;  2Z7I A;  5B0K A;  3KBK A;  3TFN A;  3UCA A;  3BNX A;  4NKF A;  2FTZ A;  3WJO A;  2AZK A;  1YHK A;  3KRP A;  1YYS A;  4KWD A;  4JVJ F;  1VG6 A;  4JYX A;  2PS4 A;  4GAX A;  3CC9 A;  3TFP A;  3G4D A;  3LVS A;  1EZF A;  5DHI A;  5B0M A;  4F6V A;  5DIQ F;  3V1V A;  4FJQ A;  3W7F A;  2EWG A;  1JFG A;  3RYE A;  3OAC B;  3CKE A;  1WL1 A;  3WEG A;  4JXN A;  2Z78 A;  4KPJ A;  4OKZ A;  4KQ5 A;  5ILJ A;  5C05 A;  5CG6 A;  3WCI A;  1DI1 A;  1N1Z A;  5E8L A;  3AQB B;  4F62 A;  3RMG A;  3APZ A;  5ERN A;  4GP2 A;  2F89 F;  5IMP A;  4DWB A;  4LTZ A;  1RTR A;  3M01 A;  4LUU A;  5IVG A;  4DI5 A;  2J5C A;  3WEI A;  4LA5 A;  1RQJ A;  3Q2Q A;  5EAT A;  1YYU A;  2AZJ A;  2AZL A;  4NFI F;  5AYP A;  3LK5 A;  4MC3 A;  2E8T A;  4RYP A;  3BNY A;  3ZL6 A;  2OA6 A;  5B0L A;  3ID0 A;  5B03 A;  1YQ7 A;  4NUA A;  4HD1 A;  3KRF A;  3QKC A;  1HXA A;  4LPH F;  3ADZ A;  3V1X A;  5AEL A;  4KKM A;  3P8R A;  5DGN F;  5A0J A;  5B01 A;  1WL0 A;  2Z4V A;  4LFV F;  5KSX F;  3WJK A;  4MC0 A;  5AFX A;  3PH7 A;  1YYQ A;  5ERM A;  3SDT A;  5B02 A;  5JV2 F;  4OGU A;  4LZ0 A;  4LFE A;  5ILY A;  3N49 F;  3LGZ B;  2QIS A;  4PVX F;  3ASX A;  2Q9Y A;  2E8U A;  5DHK A;  4KK2 A;  3VJA A;  2ZCQ A;  4DXJ A;  3WC9 A;  4PVY F;  3LGK A;  3LMD A;  5JV1 F;  3VJB A;  4EA1 A;  5ILI A;  3V66 A;  4GA3 A;  4KUX A;  2F8Z F;  3N3D A;  4DWG A;  5IK0 A;  2E8X A;  4N9U A;  3Q30 A;  1N20 A;  4LOB A;  4Q23 A;  4LTV A;  5HNA A;  5DJP F;  3VJD A;  4XQS F;  2O1O A;  2Z4X A;  4H5C F;  4RXE A;  3N6K F;  4KVD A;  3N5H F;  3Q2Z A;  5JV0 F;  2I19 A;  2AET A;  3DYF A;  4H5E F;  3WCH A;  4JXY A;  4EA2 A;  2E95 A;  1HXG A;  2F9K F;  4QXS F;  3LEE A;  3S4J A;  1WY0 A;  3PYB A;  2Q58 A;  3ZMB A;  2PS7 A;  5ERO A;  1N22 A;  3M02 A;  4L2X F;  3WCA A;  2F94 F;  4LFG A;  1V4J A;  5HN8 A;  2E94 A;  4RXD A;  3KB9 A;  3IBA A;  1YYR A;  3ICK A;  1ZW5 A;  3WSA A;  4RXC A;  3N45 F;  3N1V F;  4RNQ A;  5ILK A;  2ZEU A;  4LIX A;  1YHL A;  2E92 A;  3OYR A;  4KQU A;  3DYH A;  3WEH A;  3CP6 A;  1UBV A;  3LZ9 A;  3AE0 A;  3QQV A;  5E8H A;  1V4I A;  3ICZ A;  1WL3 A;  1YJ4 A;  2Z4Y A;  5DJV F;  3AQ0 A;  3N0F A;  3ZOU A;  1N23 A;  3N0G A;  5ILZ A;  2Z52 A;  3P8L A;  2Q80 A;  1VG4 A;  5H9D A;  5DGS F;  5ILH A;  3KRA A;  3ZCD A;  2E93 A;  3KRC B;  3M00 A;  4DEM F;  3TFV A;  4KVY A;  3ZMC A;  4OMG A;  1WKZ A;  2Z7H A;  5AHU B;  3NPR A;  3OAB A;  2PS8 A;  5B0J A;  5IM1 A;  1VG2 A;  4UMJ A;  1FPS A;  3M0G A;  1WMW A;  3ACX A;  3MAV A;  2AEL A;  3PDE A;  3LJI A;  3KRP B;  2ZEV A;  5IMN A;  5IL3 A;  3VJE A;  5DGM F;  4NFK F;  2F92 F;  3KRO A;  3AQC B;  3WEF A;  3TS7 A;  3WCD A;  4LLS A;  3IPI A;  5I1U A;  3M9U A;  1YYT A;  2ZCR A;  1V4K A;  3WCG A;  3EFQ A;  5IKH A;  4QPF A;  4P0W A;  1HM4 A;  3TC1 A;  3Q1O A;  4F6X A;  3ICN A;  2FOR A;  1WL2 A;  5A0K A;  3LOM A;  2PS6 A;  3SDR A;  2Z4W A;  2OPM A;  1DGP A;  3ACW A;  2OGD A;  4WK5 A;  1KIZ A;  5IK9 A;  3LLW A;  4NFJ F;  4DZW A;  5DZ2 A;  3WCJ A;  5IL8 A;  3PYA A;  3G4F A;  5A0I A;  2DH4 A;  4OMH A;  2E90 A;  3N1W F;  1V4H A;  2RAH A;  3SAE A;  4LLT A;  1UBX A;  2VF6 A;  5HN9 A;  5JA0 F;  4K10 A;  2P1C A;  4RXA A;  1HM7 A;  2E4O A;  3P5P A;  1JFA A;  4JZB A;  3KRF B;  3P5R A;  3WEJ A;  2E91 A;  3KRA B;  4KFA A;  3S9V A;  3WJN A;  3LSN A;  4E1E A;  4JZX A;  1UBY A;  5DJR F;  3OAB B;  3WE9 A;  1PS1 A;  4LXW A;  1UBW A;  4LA6 A;  3RYW A;  3ACY A;  4E9Z A; 
#chains in the Genus database with same CATH topology
 3RBM A;  3WCF A;  3WCE A;  2ONH A;  5B00 A;  4KVW A;  2PS5 A;  3WSB A;  4P0V A;  5IN8 A;  3KRO B;  2ZY1 A;  3ICM A;  4FP4 A;  4KPD A;  4OKM A;  4LZ3 A;  3PKO A;  4MC8 A;  1YHM A;  2Q9Z A;  3DYG A;  2ZCS A;  4LZC A;  3NRI A;  4LPG F;  3WEK A;  3N5J F;  3N46 F;  3WCL A;  3EGT A;  4N1Z F;  3LG5 A;  3VJ9 A;  4GP1 A;  2E8W A;  2H8O A;  5ER8 A;  4XQT F;  4P0X A;  5IKA A;  5HN7 A;  5IK6 A;  1N21 A;  4DHD A;  2F7M F;  3OAC A;  1VG7 A;  1N24 A;  2Z4Z A;  4XQR F;  2J1O A;  3P41 A;  3EZ3 A;  3WCC A;  2F8C F;  5E8K A;  3NF2 A;  3NPK A;  4ZQ8 A;  2ONG A;  1RQI A;  3LDW A;  3SDQ A;  4EA0 A;  4NG6 A;  2E8V A;  3B7L A;  3VJC A;  3WCM A;  1KIY A;  5ILD A;  1HX9 A;  1N1B A;  2Z50 A;  5DW7 A;  3N3L F;  4NKE A;  2OPN A;  1V4E A;  1VG3 A;  5EAS A;  5CG5 A;  3SDV A;  5EAU A;  3MZV A;  3SDU A;  3VJ8 A;  3WCB A;  1HXC A;  4E9U A;  2AEK A;  1YV5 A;  4KVI A;  2ZCO A;  3KRC A;  4KQS A;  5IMI A;  5JUZ F;  4H5D F;  5B0I A;  2J1P A;  2Z7I A;  5B0K A;  3KBK A;  3TFN A;  3UCA A;  3BNX A;  4NKF A;  2FTZ A;  3WJO A;  2AZK A;  1YHK A;  3KRP A;  1YYS A;  4KWD A;  4JVJ F;  1VG6 A;  4JYX A;  2PS4 A;  4GAX A;  3CC9 A;  3TFP A;  3G4D A;  3LVS A;  1EZF A;  5DHI A;  5B0M A;  4F6V A;  5DIQ F;  3V1V A;  4FJQ A;  3W7F A;  2EWG A;  1JFG A;  3RYE A;  3OAC B;  3CKE A;  1WL1 A;  3WEG A;  4JXN A;  2Z78 A;  4KPJ A;  4OKZ A;  4KQ5 A;  5ILJ A;  5C05 A;  5CG6 A;  3WCI A;  1DI1 A;  1N1Z A;  5E8L A;  3AQB B;  4F62 A;  3RMG A;  3APZ A;  5ERN A;  4GP2 A;  2F89 F;  5IMP A;  4DWB A;  4LTZ A;  1RTR A;  3M01 A;  4LUU A;  5IVG A;  4DI5 A;  2J5C A;  3WEI A;  4LA5 A;  1RQJ A;  3Q2Q A;  5EAT A;  1YYU A;  2AZJ A;  2AZL A;  4NFI F;  5AYP A;  3LK5 A;  4MC3 A;  2E8T A;  4RYP A;  3BNY A;  3ZL6 A;  2OA6 A;  5B0L A;  3ID0 A;  5B03 A;  1YQ7 A;  4NUA A;  4HD1 A;  3KRF A;  3QKC A;  1HXA A;  4LPH F;  3ADZ A;  3V1X A;  5AEL A;  4KKM A;  3P8R A;  5DGN F;  5A0J A;  5B01 A;  1WL0 A;  2Z4V A;  4LFV F;  5KSX F;  3WJK A;  4MC0 A;  5AFX A;  3PH7 A;  1YYQ A;  5ERM A;  3SDT A;  5B02 A;  5JV2 F;  4OGU A;  4LZ0 A;  4LFE A;  5ILY A;  3N49 F;  3LGZ B;  2QIS A;  4PVX F;  3ASX A;  2Q9Y A;  2E8U A;  5DHK A;  4KK2 A;  3VJA A;  2ZCQ A;  4DXJ A;  3WC9 A;  4PVY F;  3LGK A;  3LMD A;  5JV1 F;  3VJB A;  4EA1 A;  5ILI A;  3V66 A;  4GA3 A;  4KUX A;  2F8Z F;  3N3D A;  4DWG A;  5IK0 A;  2E8X A;  4N9U A;  3Q30 A;  1N20 A;  4LOB A;  4Q23 A;  4LTV A;  5HNA A;  5DJP F;  3VJD A;  4XQS F;  2O1O A;  2Z4X A;  4H5C F;  4RXE A;  3N6K F;  4KVD A;  3N5H F;  3Q2Z A;  5JV0 F;  2I19 A;  2AET A;  3DYF A;  4H5E F;  3WCH A;  4JXY A;  4EA2 A;  2E95 A;  1HXG A;  2F9K F;  4QXS F;  3LEE A;  3S4J A;  1WY0 A;  3PYB A;  2Q58 A;  3ZMB A;  2PS7 A;  5ERO A;  1N22 A;  3M02 A;  4L2X F;  3WCA A;  2F94 F;  4LFG A;  1V4J A;  5HN8 A;  2E94 A;  4RXD A;  3KB9 A;  3IBA A;  1YYR A;  3ICK A;  1ZW5 A;  3WSA A;  4RXC A;  3N45 F;  3N1V F;  4RNQ A;  5ILK A;  2ZEU A;  4LIX A;  1YHL A;  2E92 A;  3OYR A;  4KQU A;  3DYH A;  3WEH A;  3CP6 A;  1UBV A;  3LZ9 A;  3AE0 A;  3QQV A;  5E8H A;  1V4I A;  3ICZ A;  1WL3 A;  1YJ4 A;  2Z4Y A;  5DJV F;  3AQ0 A;  3N0F A;  3ZOU A;  1N23 A;  3N0G A;  5ILZ A;  2Z52 A;  3P8L A;  2Q80 A;  1VG4 A;  5H9D A;  5DGS F;  5ILH A;  3KRA A;  3ZCD A;  2E93 A;  3KRC B;  3M00 A;  4DEM F;  3TFV A;  4KVY A;  3ZMC A;  4OMG A;  1WKZ A;  2Z7H A;  5AHU B;  3NPR A;  3OAB A;  2PS8 A;  5B0J A;  5IM1 A;  1VG2 A;  4UMJ A;  1FPS A;  3M0G A;  1WMW A;  3ACX A;  3MAV A;  2AEL A;  3PDE A;  3LJI A;  3KRP B;  2ZEV A;  5IMN A;  5IL3 A;  3VJE A;  5DGM F;  4NFK F;  2F92 F;  3KRO A;  3AQC B;  3WEF A;  3TS7 A;  3WCD A;  4LLS A;  3IPI A;  5I1U A;  3M9U A;  1YYT A;  2ZCR A;  1V4K A;  3WCG A;  3EFQ A;  5IKH A;  4QPF A;  4P0W A;  1HM4 A;  3TC1 A;  3Q1O A;  4F6X A;  3ICN A;  2FOR A;  1WL2 A;  5A0K A;  3LOM A;  2PS6 A;  3SDR A;  2Z4W A;  2OPM A;  1DGP A;  3ACW A;  2OGD A;  4WK5 A;  1KIZ A;  5IK9 A;  3LLW A;  4NFJ F;  4DZW A;  5DZ2 A;  3WCJ A;  5IL8 A;  3PYA A;  3G4F A;  5A0I A;  2DH4 A;  4OMH A;  2E90 A;  3N1W F;  1V4H A;  2RAH A;  3SAE A;  4LLT A;  1UBX A;  2VF6 A;  5HN9 A;  5JA0 F;  4K10 A;  2P1C A;  4RXA A;  1HM7 A;  2E4O A;  3P5P A;  1JFA A;  4JZB A;  3KRF B;  3P5R A;  3WEJ A;  2E91 A;  3KRA B;  4KFA A;  3S9V A;  3WJN A;  3LSN A;  4E1E A;  4JZX A;  1UBY A;  5DJR F;  3OAB B;  3WE9 A;  1PS1 A;  4LXW A;  1UBW A;  4LA6 A;  3RYW A;  3ACY A;  4E9Z A; 
#chains in the Genus database with same CATH homology
 3RBM A;  3WCF A;  3WCE A;  2ONH A;  5B00 A;  4KVW A;  2PS5 A;  3WSB A;  4P0V A;  5IN8 A;  3KRO B;  2ZY1 A;  3ICM A;  4FP4 A;  4KPD A;  4OKM A;  4LZ3 A;  3PKO A;  4MC8 A;  1YHM A;  2Q9Z A;  3DYG A;  2ZCS A;  4LZC A;  3NRI A;  4LPG F;  3WEK A;  3N5J F;  3N46 F;  3WCL A;  3EGT A;  4N1Z F;  3LG5 A;  3VJ9 A;  4GP1 A;  2E8W A;  2H8O A;  5ER8 A;  4XQT F;  4P0X A;  5IKA A;  5HN7 A;  5IK6 A;  1N21 A;  4DHD A;  2F7M F;  3OAC A;  1VG7 A;  1N24 A;  2Z4Z A;  4XQR F;  2J1O A;  3P41 A;  3EZ3 A;  3WCC A;  2F8C F;  5E8K A;  3NF2 A;  3NPK A;  4ZQ8 A;  2ONG A;  1RQI A;  3LDW A;  3SDQ A;  4EA0 A;  4NG6 A;  2E8V A;  3B7L A;  3VJC A;  3WCM A;  1KIY A;  5ILD A;  1HX9 A;  1N1B A;  2Z50 A;  5DW7 A;  3N3L F;  4NKE A;  2OPN A;  1V4E A;  1VG3 A;  5EAS A;  5CG5 A;  3SDV A;  5EAU A;  3MZV A;  3SDU A;  3VJ8 A;  3WCB A;  1HXC A;  4E9U A;  2AEK A;  1YV5 A;  4KVI A;  2ZCO A;  3KRC A;  4KQS A;  5IMI A;  5JUZ F;  4H5D F;  5B0I A;  2J1P A;  2Z7I A;  5B0K A;  3KBK A;  3TFN A;  3UCA A;  3BNX A;  4NKF A;  2FTZ A;  3WJO A;  2AZK A;  1YHK A;  3KRP A;  1YYS A;  4KWD A;  4JVJ F;  1VG6 A;  4JYX A;  2PS4 A;  4GAX A;  3CC9 A;  3TFP A;  3G4D A;  3LVS A;  1EZF A;  5DHI A;  5B0M A;  4F6V A;  5DIQ F;  3V1V A;  4FJQ A;  3W7F A;  2EWG A;  1JFG A;  3RYE A;  3OAC B;  3CKE A;  1WL1 A;  3WEG A;  4JXN A;  2Z78 A;  4KPJ A;  4OKZ A;  4KQ5 A;  5ILJ A;  5C05 A;  5CG6 A;  3WCI A;  1DI1 A;  1N1Z A;  5E8L A;  3AQB B;  4F62 A;  3RMG A;  3APZ A;  5ERN A;  4GP2 A;  2F89 F;  5IMP A;  4DWB A;  4LTZ A;  1RTR A;  3M01 A;  4LUU A;  5IVG A;  4DI5 A;  2J5C A;  3WEI A;  4LA5 A;  1RQJ A;  3Q2Q A;  5EAT A;  1YYU A;  2AZJ A;  2AZL A;  4NFI F;  5AYP A;  3LK5 A;  4MC3 A;  2E8T A;  4RYP A;  3BNY A;  3ZL6 A;  2OA6 A;  5B0L A;  3ID0 A;  5B03 A;  1YQ7 A;  4NUA A;  4HD1 A;  3KRF A;  3QKC A;  1HXA A;  4LPH F;  3ADZ A;  3V1X A;  5AEL A;  4KKM A;  3P8R A;  5DGN F;  5A0J A;  5B01 A;  1WL0 A;  2Z4V A;  4LFV F;  5KSX F;  3WJK A;  4MC0 A;  5AFX A;  3PH7 A;  1YYQ A;  5ERM A;  3SDT A;  5B02 A;  5JV2 F;  4OGU A;  4LZ0 A;  4LFE A;  5ILY A;  3N49 F;  3LGZ B;  2QIS A;  4PVX F;  3ASX A;  2Q9Y A;  2E8U A;  5DHK A;  4KK2 A;  3VJA A;  2ZCQ A;  4DXJ A;  3WC9 A;  4PVY F;  3LGK A;  3LMD A;  5JV1 F;  3VJB A;  4EA1 A;  5ILI A;  3V66 A;  4GA3 A;  4KUX A;  2F8Z F;  3N3D A;  4DWG A;  5IK0 A;  2E8X A;  4N9U A;  3Q30 A;  1N20 A;  4LOB A;  4Q23 A;  4LTV A;  5HNA A;  5DJP F;  3VJD A;  4XQS F;  2O1O A;  2Z4X A;  4H5C F;  4RXE A;  3N6K F;  4KVD A;  3N5H F;  3Q2Z A;  5JV0 F;  2I19 A;  2AET A;  3DYF A;  4H5E F;  3WCH A;  4JXY A;  4EA2 A;  2E95 A;  1HXG A;  2F9K F;  4QXS F;  3LEE A;  3S4J A;  1WY0 A;  3PYB A;  2Q58 A;  3ZMB A;  2PS7 A;  5ERO A;  1N22 A;  3M02 A;  4L2X F;  3WCA A;  2F94 F;  4LFG A;  1V4J A;  5HN8 A;  2E94 A;  4RXD A;  3KB9 A;  3IBA A;  1YYR A;  3ICK A;  1ZW5 A;  3WSA A;  4RXC A;  3N45 F;  3N1V F;  4RNQ A;  5ILK A;  2ZEU A;  4LIX A;  1YHL A;  2E92 A;  3OYR A;  4KQU A;  3DYH A;  3WEH A;  3CP6 A;  1UBV A;  3LZ9 A;  3AE0 A;  3QQV A;  5E8H A;  1V4I A;  3ICZ A;  1WL3 A;  1YJ4 A;  2Z4Y A;  5DJV F;  3AQ0 A;  3N0F A;  3ZOU A;  1N23 A;  3N0G A;  5ILZ A;  2Z52 A;  3P8L A;  2Q80 A;  1VG4 A;  5H9D A;  5DGS F;  5ILH A;  3KRA A;  3ZCD A;  2E93 A;  3KRC B;  3M00 A;  4DEM F;  3TFV A;  4KVY A;  3ZMC A;  4OMG A;  1WKZ A;  2Z7H A;  5AHU B;  3NPR A;  3OAB A;  2PS8 A;  5B0J A;  5IM1 A;  1VG2 A;  4UMJ A;  1FPS A;  3M0G A;  1WMW A;  3ACX A;  3MAV A;  2AEL A;  3PDE A;  3LJI A;  3KRP B;  2ZEV A;  5IMN A;  5IL3 A;  3VJE A;  5DGM F;  4NFK F;  2F92 F;  3KRO A;  3AQC B;  3WEF A;  3TS7 A;  3WCD A;  4LLS A;  3IPI A;  5I1U A;  3M9U A;  1YYT A;  2ZCR A;  1V4K A;  3WCG A;  3EFQ A;  5IKH A;  4QPF A;  4P0W A;  1HM4 A;  3TC1 A;  3Q1O A;  4F6X A;  3ICN A;  2FOR A;  1WL2 A;  5A0K A;  3LOM A;  2PS6 A;  3SDR A;  2Z4W A;  2OPM A;  1DGP A;  3ACW A;  2OGD A;  4WK5 A;  1KIZ A;  5IK9 A;  3LLW A;  4NFJ F;  4DZW A;  5DZ2 A;  3WCJ A;  5IL8 A;  3PYA A;  3G4F A;  5A0I A;  2DH4 A;  4OMH A;  2E90 A;  3N1W F;  1V4H A;  2RAH A;  3SAE A;  4LLT A;  1UBX A;  2VF6 A;  5HN9 A;  5JA0 F;  4K10 A;  2P1C A;  4RXA A;  1HM7 A;  2E4O A;  3P5P A;  1JFA A;  4JZB A;  3KRF B;  3P5R A;  3WEJ A;  2E91 A;  3KRA B;  4KFA A;  3S9V A;  3WJN A;  3LSN A;  4E1E A;  4JZX A;  1UBY A;  5DJR F;  3OAB B;  3WE9 A;  1PS1 A;  4LXW A;  1UBW A;  4LA6 A;  3RYW A;  3ACY A;  4E9Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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