1EZFA

Crystal structure of human squalene synthase
Total Genus 131
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
131
sequence length
333
structure length
323
Chain Sequence
NSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE
publication title Crystal structure of human squalene synthase. A key enzyme in cholesterol biosynthesis.
pubmed doi rcsb
source organism Homo sapiens
total genus 131
structure length 323
sequence length 333
chains with identical sequence B, C
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2000-05-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 1ezfA00
5IN8A 4DEMF 2Q80A 2J1OA 1V4IA 1PS1A 2VF6A 2Z4WA 4KQ5A 1N1ZA 5IL3A 4RYPA 4LLSA 1WL3A 2OPNA 3P8LA 3NF2A 3NPKA 4XQRF 1WL0A 3KRFA 4FJQA 2PS4A 2E8TA 2Z52A 2Z7HA 4LLTA 1ZW5A 2Z4XA 4LIXA 4JXNA 3MZVA 3KROA 3LSNA 3N6KF 1N22A 3G4DA 3WJOA 3VJCA 2E8UA 4LFEA 4P0XA 4LOBA 3WCHA 3N3LF 3M01A 3SDVA 3CC9A 4XQTF 3OACB 4NFJF 3VJEA 3WCIA 4WK5A 1KIZA 4H5CF 5DHKA 5ILDA 4UMJA 4DHDA 4LTVA 1V4HA 4PVYF 4KKMA 2E92A 5E8KA 5DJRF 2PS7A 3VJ9A 3LK5A 5EASA 1WL1A 3WCLA 3N0GA 3WSAA 1UBVA 5HN7A 5DIQF 3N46F 2Z4YA 2E93A 2ZEUA 4QPFA 3WSBA 4KVWA 5CG6A 5ILJA 1HX9A 2AZJA 3EGTA 4EA0A 2OA6A 4OKMA 3M9UA 1YHLA 4LPGF 3ZMBA 5ILIA 2E8XA 1UBWA 4NFKF 3WJNA 4EA2A 3B7LA 2F9KF 3MAVA 2ZCRA 5ILKA 3RYEA 3M00A 5JA0F 5AHUB 1UBYA 3LGKA 5IVGA 3VJ8A 4LXWA 3TFPA 3WCFA 3ASXA 3SAEA 3WCDA 3WCMA 2Z78A 3P41A 1WMWA 3BNXA 4DWBA 3APZA 3N1VF 3WEGA 4KWDA 1HXCA 3WCBA 4E9ZA 3WEFA 4KVDA 4RXEA 4P0VA 4H5DF 3SDTA 2H8OA 5DHIA 5DJVF 3BNYA 3N5HF 3AQBB 3CP6A 3ZOUA 2ZCOA 5IMIA 3SDRA 3ACXA 4LTZA 5AYPA 2OPMA 1N20A 5B0IA 3S4JA 1FPSA 3KRAA 5EAUA 3AE0A 2Z4ZA 5A0KA 1WL2A 4DI5A 3ZMCA 3LOMA 3Q2ZA 4JYXA 2E95A 3PYBA 4ZQ8A 4N1ZF 3V1VA 3NRIA 2Z50A 3P5PA 3KRPB 4F6XA 1HM7A 4RXCA 5DGSF 4H5EF 4LA6A 4F6VA 3LMDA 4LA5A 4OGUA 3WEHA 4HD1A 2F7MF 3AQCB 3M0GA 3WC9A 5B0LA 4E1EA 1N21A 2O1OA 5IL8A 3TS7A 4KQUA 3ACWA 5B0MA 5C05A 1YHKA 4KPJA 5JV1F 2J1PA 2P1CA 3LG5A 4KVYA 1DI1A 4PVXF 3W7FA 5ERNA 3V66A 1VG4A 4OKZA 2AETA 1HXGA 5I1UA 1YYSA 5H9DA 5IK0A 2PS5A 3LLWA 4KUXA 3ACYA 3OABA 5B00A 4GAXA 4KK2A 2ZY1A 4FP4A 4KVIA 4JXYA 3N5JF 4L2XF 5E8HA 3LVSA 5ILYA 5E8LA 3TFVA 3WE9A 1HM4A 2E8VA 3PH7A 5IKHA 1WKZA 4MC8A 1VG7A 3LDWA 2QISA 3UCAA 5AFXA 2OGDA 4Q23A 3IPIA 1YYTA 3RMGA 2AELA 2F89F 3ZL6A 4DXJA 1YYRA 4RXDA 3WEKA 4LZ0A 3WCCA 5JV2F 1HXAA 1VG6A 3LEEA 1YHMA 1DGPA 5IK9A 3KBKA 3KRCB 4JVJF 4NKFA 1JFGA 5HN9A 2FTZA 1JFAA 2PS8A 4MC0A 2I19A 3WEJA 2AZLA 2F8CF 1RQJA 1YYQA 2Q9ZA 3ID0A 1YYUA 5KSXF 3TFNA 3CKEA 4NUAA 5B0JA 3Q2QA 5ILZA 5DGNF 2E90A 3PYAA 3DYHA 4LZ3A 3WJKA 3N1WF 4NFIF 4K10A 1VG3A 3N3DA 3NPRA 5B03A 2E94A 4GP2A 3OACA 2E91A 2J5CA 5HN8A 2AZKA 3WCAA 3P5RA 2E8WA 4NKEA 5JUZF 4F62A 4MC3A 1N24A 5DZ2A 1YJ4A 5A0IA 3ICNA 2FORA 4GP1A 5B0KA 3KRAB 4LFVF 5IK6A 5IMNA 3WEIA 2E4OA 5B02A 4LFGA 4OMGA 1N1BA 3ICZA 3LZ9A 4KQSA 4DZWA 4RXAA 3KRFB 5A0JA 3M02A 3TC1A 5EROA 5B01A 3RYWA 3ICMA 2Z4VA 3DYGA 3SDUA 2ONGA 3KROB 3V1XA 1KIYA 3LJIA 1EZFA 2PS6A 3AQ0A 1RTRA 2F94F 3VJDA 3ICKA 3QKCA 2F8ZF 2Q58A 2ZCSA 4LZCA 4JZBA 4EA1A 5DJPF 5ER8A 5ILHA 5ERMA 3LGZB 3DYFA 3WCEA 1YV5A 4DWGA 3KB9A 5IMPA 3PKOA 1WY0A 4KFAA 3EZ3A 4OMHA 3RBMA 1RQIA 3OYRA 2ZCQA 3G4FA 3OABB 3KRCA 4N9UA 5CG5A 1V4EA 4KPDA 3SDQA 3VJAA 3IBAA 1YQ7A 5HNAA 1VG2A 3N45F 1V4KA 2AEKA 3PDEA 3N0FA 5IM1A 3WCJA 2Q9YA 3N49F 2ZEVA 4GA3A 4LUUA 5JV0F 4JZXA 2EWGA 5EATA 3EFQA 3ADZA 2Z7IA 4XQSF 3WCGA 4RNQA 2ONHA 4NG6A 3VJBA 3S9VA 2F92F 3KRPA 4QXSF 5IKAA 1UBXA 3QQVA 2RAHA 1N23A 3P8RA 3Q1OA 5DGMF 3Q30A 4E9UA 5DW7A 5AELA 2DH4A 4LPHF 4P0WA 3ZCDA 1V4JA
chains in the Genus database with same CATH superfamily
5IN8A 4DEMF 2Q80A 2J1OA 1V4IA 1PS1A 2VF6A 2Z4WA 4KQ5A 1N1ZA 5IL3A 4RYPA 4LLSA 1WL3A 2OPNA 3P8LA 3NF2A 3NPKA 4XQRF 1WL0A 3KRFA 4FJQA 2PS4A 2E8TA 2Z52A 2Z7HA 4LLTA 1ZW5A 2Z4XA 4LIXA 4JXNA 3MZVA 3KROA 3LSNA 3N6KF 1N22A 3G4DA 3WJOA 3VJCA 2E8UA 4LFEA 4P0XA 4LOBA 3WCHA 3N3LF 3M01A 3SDVA 3CC9A 4XQTF 3OACB 4NFJF 3VJEA 3WCIA 4WK5A 1KIZA 4H5CF 5DHKA 5ILDA 4UMJA 4DHDA 4LTVA 1V4HA 4PVYF 4KKMA 2E92A 5E8KA 5DJRF 2PS7A 3VJ9A 3LK5A 5EASA 1WL1A 3WCLA 3N0GA 3WSAA 1UBVA 5HN7A 5DIQF 3N46F 2Z4YA 2E93A 2ZEUA 4QPFA 3WSBA 4KVWA 5CG6A 5ILJA 1HX9A 2AZJA 3EGTA 4EA0A 2OA6A 4OKMA 3M9UA 1YHLA 4LPGF 3ZMBA 5ILIA 2E8XA 1UBWA 4NFKF 3WJNA 4EA2A 3B7LA 2F9KF 3MAVA 2ZCRA 5ILKA 3RYEA 3M00A 5JA0F 5AHUB 1UBYA 3LGKA 5IVGA 3VJ8A 4LXWA 3TFPA 3WCFA 3ASXA 3SAEA 3WCDA 3WCMA 2Z78A 3P41A 1WMWA 3BNXA 4DWBA 3APZA 3N1VF 3WEGA 4KWDA 1HXCA 3WCBA 4E9ZA 3WEFA 4KVDA 4RXEA 4P0VA 4H5DF 3SDTA 2H8OA 5DHIA 5DJVF 3BNYA 3N5HF 3AQBB 3CP6A 3ZOUA 2ZCOA 5IMIA 3SDRA 3ACXA 4LTZA 5AYPA 2OPMA 1N20A 5B0IA 3S4JA 1FPSA 3KRAA 5EAUA 3AE0A 2Z4ZA 5A0KA 1WL2A 4DI5A 3ZMCA 3LOMA 3Q2ZA 4JYXA 2E95A 3PYBA 4ZQ8A 4N1ZF 3V1VA 3NRIA 2Z50A 3P5PA 3KRPB 4F6XA 1HM7A 4RXCA 5DGSF 4H5EF 4LA6A 4F6VA 3LMDA 4LA5A 4OGUA 3WEHA 4HD1A 2F7MF 3AQCB 3M0GA 3WC9A 5B0LA 4E1EA 1N21A 2O1OA 5IL8A 3TS7A 4KQUA 3ACWA 5B0MA 5C05A 1YHKA 4KPJA 5JV1F 2J1PA 2P1CA 3LG5A 4KVYA 1DI1A 4PVXF 3W7FA 5ERNA 3V66A 1VG4A 4OKZA 2AETA 1HXGA 5I1UA 1YYSA 5H9DA 5IK0A 2PS5A 3LLWA 4KUXA 3ACYA 3OABA 5B00A 4GAXA 4KK2A 2ZY1A 4FP4A 4KVIA 4JXYA 3N5JF 4L2XF 5E8HA 3LVSA 5ILYA 5E8LA 3TFVA 3WE9A 1HM4A 2E8VA 3PH7A 5IKHA 1WKZA 4MC8A 1VG7A 3LDWA 2QISA 3UCAA 5AFXA 2OGDA 4Q23A 3IPIA 1YYTA 3RMGA 2AELA 2F89F 3ZL6A 4DXJA 1YYRA 4RXDA 3WEKA 4LZ0A 3WCCA 5JV2F 1HXAA 1VG6A 3LEEA 1YHMA 1DGPA 5IK9A 3KBKA 3KRCB 4JVJF 4NKFA 1JFGA 5HN9A 2FTZA 1JFAA 2PS8A 4MC0A 2I19A 3WEJA 2AZLA 2F8CF 1RQJA 1YYQA 2Q9ZA 3ID0A 1YYUA 5KSXF 3TFNA 3CKEA 4NUAA 5B0JA 3Q2QA 5ILZA 5DGNF 2E90A 3PYAA 3DYHA 4LZ3A 3WJKA 3N1WF 4NFIF 4K10A 1VG3A 3N3DA 3NPRA 5B03A 2E94A 4GP2A 3OACA 2E91A 2J5CA 5HN8A 2AZKA 3WCAA 3P5RA 2E8WA 4NKEA 5JUZF 4F62A 4MC3A 1N24A 5DZ2A 1YJ4A 5A0IA 3ICNA 2FORA 4GP1A 5B0KA 3KRAB 4LFVF 5IK6A 5IMNA 3WEIA 2E4OA 5B02A 4LFGA 4OMGA 1N1BA 3ICZA 3LZ9A 4KQSA 4DZWA 4RXAA 3KRFB 5A0JA 3M02A 3TC1A 5EROA 5B01A 3RYWA 3ICMA 2Z4VA 3DYGA 3SDUA 2ONGA 3KROB 3V1XA 1KIYA 3LJIA 1EZFA 2PS6A 3AQ0A 1RTRA 2F94F 3VJDA 3ICKA 3QKCA 2F8ZF 2Q58A 2ZCSA 4LZCA 4JZBA 4EA1A 5DJPF 5ER8A 5ILHA 5ERMA 3LGZB 3DYFA 3WCEA 1YV5A 4DWGA 3KB9A 5IMPA 3PKOA 1WY0A 4KFAA 3EZ3A 4OMHA 3RBMA 1RQIA 3OYRA 2ZCQA 3G4FA 3OABB 3KRCA 4N9UA 5CG5A 1V4EA 4KPDA 3SDQA 3VJAA 3IBAA 1YQ7A 5HNAA 1VG2A 3N45F 1V4KA 2AEKA 3PDEA 3N0FA 5IM1A 3WCJA 2Q9YA 3N49F 2ZEVA 4GA3A 4LUUA 5JV0F 4JZXA 2EWGA 5EATA 3EFQA 3ADZA 2Z7IA 4XQSF 3WCGA 4RNQA 2ONHA 4NG6A 3VJBA 3S9VA 2F92F 3KRPA 4QXSF 5IKAA 1UBXA 3QQVA 2RAHA 1N23A 3P8RA 3Q1OA 5DGMF 3Q30A 4E9UA 5DW7A 5AELA 2DH4A 4LPHF 4P0WA 3ZCDA 1V4JA
chains in the Genus database with same CATH topology
5IN8A 4DEMF 2Q80A 2J1OA 1V4IA 1PS1A 2VF6A 2Z4WA 4KQ5A 1N1ZA 5IL3A 4RYPA 4LLSA 1WL3A 2OPNA 3P8LA 3NF2A 3NPKA 4XQRF 1WL0A 3KRFA 4FJQA 2PS4A 2E8TA 2Z52A 2Z7HA 4LLTA 1ZW5A 2Z4XA 4LIXA 4JXNA 3MZVA 3KROA 3LSNA 3N6KF 1N22A 3G4DA 3WJOA 3VJCA 2E8UA 4LFEA 4P0XA 4LOBA 3WCHA 3N3LF 3M01A 3SDVA 3CC9A 4XQTF 3OACB 4NFJF 3VJEA 3WCIA 4WK5A 1KIZA 4H5CF 5DHKA 5ILDA 4UMJA 4DHDA 4LTVA 1V4HA 4PVYF 4KKMA 2E92A 5E8KA 5DJRF 2PS7A 3VJ9A 3LK5A 5EASA 1WL1A 3WCLA 3N0GA 3WSAA 1UBVA 5HN7A 5DIQF 3N46F 2Z4YA 2E93A 2ZEUA 4QPFA 3WSBA 4KVWA 5CG6A 5ILJA 1HX9A 2AZJA 3EGTA 4EA0A 2OA6A 4OKMA 3M9UA 1YHLA 4LPGF 3ZMBA 5ILIA 2E8XA 1UBWA 4NFKF 3WJNA 4EA2A 3B7LA 2F9KF 3MAVA 2ZCRA 5ILKA 3RYEA 3M00A 5JA0F 5AHUB 1UBYA 3LGKA 5IVGA 3VJ8A 4LXWA 3TFPA 3WCFA 3ASXA 3SAEA 3WCDA 3WCMA 2Z78A 3P41A 1WMWA 3BNXA 4DWBA 3APZA 3N1VF 3WEGA 4KWDA 1HXCA 3WCBA 4E9ZA 3WEFA 4KVDA 4RXEA 4P0VA 4H5DF 3SDTA 2H8OA 5DHIA 5DJVF 3BNYA 3N5HF 3AQBB 3CP6A 3ZOUA 2ZCOA 5IMIA 3SDRA 3ACXA 4LTZA 5AYPA 2OPMA 1N20A 5B0IA 3S4JA 1FPSA 3KRAA 5EAUA 3AE0A 2Z4ZA 5A0KA 1WL2A 4DI5A 3ZMCA 3LOMA 3Q2ZA 4JYXA 2E95A 3PYBA 4ZQ8A 4N1ZF 3V1VA 3NRIA 2Z50A 3P5PA 3KRPB 4F6XA 1HM7A 4RXCA 5DGSF 4H5EF 4LA6A 4F6VA 3LMDA 4LA5A 4OGUA 3WEHA 4HD1A 2F7MF 3AQCB 3M0GA 3WC9A 5B0LA 4E1EA 1N21A 2O1OA 5IL8A 3TS7A 4KQUA 3ACWA 5B0MA 5C05A 1YHKA 4KPJA 5JV1F 2J1PA 2P1CA 3LG5A 4KVYA 1DI1A 4PVXF 3W7FA 5ERNA 3V66A 1VG4A 4OKZA 2AETA 1HXGA 5I1UA 1YYSA 5H9DA 5IK0A 2PS5A 3LLWA 4KUXA 3ACYA 3OABA 5B00A 4GAXA 4KK2A 2ZY1A 4FP4A 4KVIA 4JXYA 3N5JF 4L2XF 5E8HA 3LVSA 5ILYA 5E8LA 3TFVA 3WE9A 1HM4A 2E8VA 3PH7A 5IKHA 1WKZA 4MC8A 1VG7A 3LDWA 2QISA 3UCAA 5AFXA 2OGDA 4Q23A 3IPIA 1YYTA 3RMGA 2AELA 2F89F 3ZL6A 4DXJA 1YYRA 4RXDA 3WEKA 4LZ0A 3WCCA 5JV2F 1HXAA 1VG6A 3LEEA 1YHMA 1DGPA 5IK9A 3KBKA 3KRCB 4JVJF 4NKFA 1JFGA 5HN9A 2FTZA 1JFAA 2PS8A 4MC0A 2I19A 3WEJA 2AZLA 2F8CF 1RQJA 1YYQA 2Q9ZA 3ID0A 1YYUA 5KSXF 3TFNA 3CKEA 4NUAA 5B0JA 3Q2QA 5ILZA 5DGNF 2E90A 3PYAA 3DYHA 4LZ3A 3WJKA 3N1WF 4NFIF 4K10A 1VG3A 3N3DA 3NPRA 5B03A 2E94A 4GP2A 3OACA 2E91A 2J5CA 5HN8A 2AZKA 3WCAA 3P5RA 2E8WA 4NKEA 5JUZF 4F62A 4MC3A 1N24A 5DZ2A 1YJ4A 5A0IA 3ICNA 2FORA 4GP1A 5B0KA 3KRAB 4LFVF 5IK6A 5IMNA 3WEIA 2E4OA 5B02A 4LFGA 4OMGA 1N1BA 3ICZA 3LZ9A 4KQSA 4DZWA 4RXAA 3KRFB 5A0JA 3M02A 3TC1A 5EROA 5B01A 3RYWA 3ICMA 2Z4VA 3DYGA 3SDUA 2ONGA 3KROB 3V1XA 1KIYA 3LJIA 1EZFA 2PS6A 3AQ0A 1RTRA 2F94F 3VJDA 3ICKA 3QKCA 2F8ZF 2Q58A 2ZCSA 4LZCA 4JZBA 4EA1A 5DJPF 5ER8A 5ILHA 5ERMA 3LGZB 3DYFA 3WCEA 1YV5A 4DWGA 3KB9A 5IMPA 3PKOA 1WY0A 4KFAA 3EZ3A 4OMHA 3RBMA 1RQIA 3OYRA 2ZCQA 3G4FA 3OABB 3KRCA 4N9UA 5CG5A 1V4EA 4KPDA 3SDQA 3VJAA 3IBAA 1YQ7A 5HNAA 1VG2A 3N45F 1V4KA 2AEKA 3PDEA 3N0FA 5IM1A 3WCJA 2Q9YA 3N49F 2ZEVA 4GA3A 4LUUA 5JV0F 4JZXA 2EWGA 5EATA 3EFQA 3ADZA 2Z7IA 4XQSF 3WCGA 4RNQA 2ONHA 4NG6A 3VJBA 3S9VA 2F92F 3KRPA 4QXSF 5IKAA 1UBXA 3QQVA 2RAHA 1N23A 3P8RA 3Q1OA 5DGMF 3Q30A 4E9UA 5DW7A 5AELA 2DH4A 4LPHF 4P0WA 3ZCDA 1V4JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IN8 A;  4DEM F;  2Q80 A;  2J1O A;  1V4I A;  1PS1 A;  2VF6 A;  2Z4W A;  4KQ5 A;  1N1Z A;  5IL3 A;  4RYP A;  4LLS A;  1WL3 A;  2OPN A;  3P8L A;  3NF2 A;  3NPK A;  4XQR F;  1WL0 A;  3KRF A;  4FJQ A;  2PS4 A;  2E8T A;  2Z52 A;  2Z7H A;  4LLT A;  1ZW5 A;  2Z4X A;  4LIX A;  4JXN A;  3MZV A;  3KRO A;  3LSN A;  3N6K F;  1N22 A;  3G4D A;  3WJO A;  3VJC A;  2E8U A;  4LFE A;  4P0X A;  4LOB A;  3WCH A;  3N3L F;  3M01 A;  3SDV A;  3CC9 A;  4XQT F;  3OAC B;  4NFJ F;  3VJE A;  3WCI A;  4WK5 A;  1KIZ A;  4H5C F;  5DHK A;  5ILD A;  4UMJ A;  4DHD A;  4LTV A;  1V4H A;  4PVY F;  4KKM A;  2E92 A;  5E8K A;  5DJR F;  2PS7 A;  3VJ9 A;  3LK5 A;  5EAS A;  1WL1 A;  3WCL A;  3N0G A;  3WSA A;  1UBV A;  5HN7 A;  5DIQ F;  3N46 F;  2Z4Y A;  2E93 A;  2ZEU A;  4QPF A;  3WSB A;  4KVW A;  5CG6 A;  5ILJ A;  1HX9 A;  2AZJ A;  3EGT A;  4EA0 A;  2OA6 A;  4OKM A;  3M9U A;  1YHL A;  4LPG F;  3ZMB A;  5ILI A;  2E8X A;  1UBW A;  4NFK F;  3WJN A;  4EA2 A;  3B7L A;  2F9K F;  3MAV A;  2ZCR A;  5ILK A;  3RYE A;  3M00 A;  5JA0 F;  5AHU B;  1UBY A;  3LGK A;  5IVG A;  3VJ8 A;  4LXW A;  3TFP A;  3WCF A;  3ASX A;  3SAE A;  3WCD A;  3WCM A;  2Z78 A;  3P41 A;  1WMW A;  3BNX A;  4DWB A;  3APZ A;  3N1V F;  3WEG A;  4KWD A;  1HXC A;  3WCB A;  4E9Z A;  3WEF A;  4KVD A;  4RXE A;  4P0V A;  4H5D F;  3SDT A;  2H8O A;  5DHI A;  5DJV F;  3BNY A;  3N5H F;  3AQB B;  3CP6 A;  3ZOU A;  2ZCO A;  5IMI A;  3SDR A;  3ACX A;  4LTZ A;  5AYP A;  2OPM A;  1N20 A;  5B0I A;  3S4J A;  1FPS A;  3KRA A;  5EAU A;  3AE0 A;  2Z4Z A;  5A0K A;  1WL2 A;  4DI5 A;  3ZMC A;  3LOM A;  3Q2Z A;  4JYX A;  2E95 A;  3PYB A;  4ZQ8 A;  4N1Z F;  3V1V A;  3NRI A;  2Z50 A;  3P5P A;  3KRP B;  4F6X A;  1HM7 A;  4RXC A;  5DGS F;  4H5E F;  4LA6 A;  4F6V A;  3LMD A;  4LA5 A;  4OGU A;  3WEH A;  4HD1 A;  2F7M F;  3AQC B;  3M0G A;  3WC9 A;  5B0L A;  4E1E A;  1N21 A;  2O1O A;  5IL8 A;  3TS7 A;  4KQU A;  3ACW A;  5B0M A;  5C05 A;  1YHK A;  4KPJ A;  5JV1 F;  2J1P A;  2P1C A;  3LG5 A;  4KVY A;  1DI1 A;  4PVX F;  3W7F A;  5ERN A;  3V66 A;  1VG4 A;  4OKZ A;  2AET A;  1HXG A;  5I1U A;  1YYS A;  5H9D A;  5IK0 A;  2PS5 A;  3LLW A;  4KUX A;  3ACY A;  3OAB A;  5B00 A;  4GAX A;  4KK2 A;  2ZY1 A;  4FP4 A;  4KVI A;  4JXY A;  3N5J F;  4L2X F;  5E8H A;  3LVS A;  5ILY A;  5E8L A;  3TFV A;  3WE9 A;  1HM4 A;  2E8V A;  3PH7 A;  5IKH A;  1WKZ A;  4MC8 A;  1VG7 A;  3LDW A;  2QIS A;  3UCA A;  5AFX A;  2OGD A;  4Q23 A;  3IPI A;  1YYT A;  3RMG A;  2AEL A;  2F89 F;  3ZL6 A;  4DXJ A;  1YYR A;  4RXD A;  3WEK A;  4LZ0 A;  3WCC A;  5JV2 F;  1HXA A;  1VG6 A;  3LEE A;  1YHM A;  1DGP A;  5IK9 A;  3KBK A;  3KRC B;  4JVJ F;  4NKF A;  1JFG A;  5HN9 A;  2FTZ A;  1JFA A;  2PS8 A;  4MC0 A;  2I19 A;  3WEJ A;  2AZL A;  2F8C F;  1RQJ A;  1YYQ A;  2Q9Z A;  3ID0 A;  1YYU A;  5KSX F;  3TFN A;  3CKE A;  4NUA A;  5B0J A;  3Q2Q A;  5ILZ A;  5DGN F;  2E90 A;  3PYA A;  3DYH A;  4LZ3 A;  3WJK A;  3N1W F;  4NFI F;  4K10 A;  1VG3 A;  3N3D A;  3NPR A;  5B03 A;  2E94 A;  4GP2 A;  3OAC A;  2E91 A;  2J5C A;  5HN8 A;  2AZK A;  3WCA A;  3P5R A;  2E8W A;  4NKE A;  5JUZ F;  4F62 A;  4MC3 A;  1N24 A;  5DZ2 A;  1YJ4 A;  5A0I A;  3ICN A;  2FOR A;  4GP1 A;  5B0K A;  3KRA B;  4LFV F;  5IK6 A;  5IMN A;  3WEI A;  2E4O A;  5B02 A;  4LFG A;  4OMG A;  1N1B A;  3ICZ A;  3LZ9 A;  4KQS A;  4DZW A;  4RXA A;  3KRF B;  5A0J A;  3M02 A;  3TC1 A;  5ERO A;  5B01 A;  3RYW A;  3ICM A;  2Z4V A;  3DYG A;  3SDU A;  2ONG A;  3KRO B;  3V1X A;  1KIY A;  3LJI A;  1EZF A;  2PS6 A;  3AQ0 A;  1RTR A;  2F94 F;  3VJD A;  3ICK A;  3QKC A;  2F8Z F;  2Q58 A;  2ZCS A;  4LZC A;  4JZB A;  4EA1 A;  5DJP F;  5ER8 A;  5ILH A;  5ERM A;  3LGZ B;  3DYF A;  3WCE A;  1YV5 A;  4DWG A;  3KB9 A;  5IMP A;  3PKO A;  1WY0 A;  4KFA A;  3EZ3 A;  4OMH A;  3RBM A;  1RQI A;  3OYR A;  2ZCQ A;  3G4F A;  3OAB B;  3KRC A;  4N9U A;  5CG5 A;  1V4E A;  4KPD A;  3SDQ A;  3VJA A;  3IBA A;  1YQ7 A;  5HNA A;  1VG2 A;  3N45 F;  1V4K A;  2AEK A;  3PDE A;  3N0F A;  5IM1 A;  3WCJ A;  2Q9Y A;  3N49 F;  2ZEV A;  4GA3 A;  4LUU A;  5JV0 F;  4JZX A;  2EWG A;  5EAT A;  3EFQ A;  3ADZ A;  2Z7I A;  4XQS F;  3WCG A;  4RNQ A;  2ONH A;  4NG6 A;  3VJB A;  3S9V A;  2F92 F;  3KRP A;  4QXS F;  5IKA A;  1UBX A;  3QQV A;  2RAH A;  1N23 A;  3P8R A;  3Q1O A;  5DGM F;  3Q30 A;  4E9U A;  5DW7 A;  5AEL A;  2DH4 A;  4LPH F;  4P0W A;  3ZCD A;  1V4J A; 
#chains in the Genus database with same CATH topology
 5IN8 A;  4DEM F;  2Q80 A;  2J1O A;  1V4I A;  1PS1 A;  2VF6 A;  2Z4W A;  4KQ5 A;  1N1Z A;  5IL3 A;  4RYP A;  4LLS A;  1WL3 A;  2OPN A;  3P8L A;  3NF2 A;  3NPK A;  4XQR F;  1WL0 A;  3KRF A;  4FJQ A;  2PS4 A;  2E8T A;  2Z52 A;  2Z7H A;  4LLT A;  1ZW5 A;  2Z4X A;  4LIX A;  4JXN A;  3MZV A;  3KRO A;  3LSN A;  3N6K F;  1N22 A;  3G4D A;  3WJO A;  3VJC A;  2E8U A;  4LFE A;  4P0X A;  4LOB A;  3WCH A;  3N3L F;  3M01 A;  3SDV A;  3CC9 A;  4XQT F;  3OAC B;  4NFJ F;  3VJE A;  3WCI A;  4WK5 A;  1KIZ A;  4H5C F;  5DHK A;  5ILD A;  4UMJ A;  4DHD A;  4LTV A;  1V4H A;  4PVY F;  4KKM A;  2E92 A;  5E8K A;  5DJR F;  2PS7 A;  3VJ9 A;  3LK5 A;  5EAS A;  1WL1 A;  3WCL A;  3N0G A;  3WSA A;  1UBV A;  5HN7 A;  5DIQ F;  3N46 F;  2Z4Y A;  2E93 A;  2ZEU A;  4QPF A;  3WSB A;  4KVW A;  5CG6 A;  5ILJ A;  1HX9 A;  2AZJ A;  3EGT A;  4EA0 A;  2OA6 A;  4OKM A;  3M9U A;  1YHL A;  4LPG F;  3ZMB A;  5ILI A;  2E8X A;  1UBW A;  4NFK F;  3WJN A;  4EA2 A;  3B7L A;  2F9K F;  3MAV A;  2ZCR A;  5ILK A;  3RYE A;  3M00 A;  5JA0 F;  5AHU B;  1UBY A;  3LGK A;  5IVG A;  3VJ8 A;  4LXW A;  3TFP A;  3WCF A;  3ASX A;  3SAE A;  3WCD A;  3WCM A;  2Z78 A;  3P41 A;  1WMW A;  3BNX A;  4DWB A;  3APZ A;  3N1V F;  3WEG A;  4KWD A;  1HXC A;  3WCB A;  4E9Z A;  3WEF A;  4KVD A;  4RXE A;  4P0V A;  4H5D F;  3SDT A;  2H8O A;  5DHI A;  5DJV F;  3BNY A;  3N5H F;  3AQB B;  3CP6 A;  3ZOU A;  2ZCO A;  5IMI A;  3SDR A;  3ACX A;  4LTZ A;  5AYP A;  2OPM A;  1N20 A;  5B0I A;  3S4J A;  1FPS A;  3KRA A;  5EAU A;  3AE0 A;  2Z4Z A;  5A0K A;  1WL2 A;  4DI5 A;  3ZMC A;  3LOM A;  3Q2Z A;  4JYX A;  2E95 A;  3PYB A;  4ZQ8 A;  4N1Z F;  3V1V A;  3NRI A;  2Z50 A;  3P5P A;  3KRP B;  4F6X A;  1HM7 A;  4RXC A;  5DGS F;  4H5E F;  4LA6 A;  4F6V A;  3LMD A;  4LA5 A;  4OGU A;  3WEH A;  4HD1 A;  2F7M F;  3AQC B;  3M0G A;  3WC9 A;  5B0L A;  4E1E A;  1N21 A;  2O1O A;  5IL8 A;  3TS7 A;  4KQU A;  3ACW A;  5B0M A;  5C05 A;  1YHK A;  4KPJ A;  5JV1 F;  2J1P A;  2P1C A;  3LG5 A;  4KVY A;  1DI1 A;  4PVX F;  3W7F A;  5ERN A;  3V66 A;  1VG4 A;  4OKZ A;  2AET A;  1HXG A;  5I1U A;  1YYS A;  5H9D A;  5IK0 A;  2PS5 A;  3LLW A;  4KUX A;  3ACY A;  3OAB A;  5B00 A;  4GAX A;  4KK2 A;  2ZY1 A;  4FP4 A;  4KVI A;  4JXY A;  3N5J F;  4L2X F;  5E8H A;  3LVS A;  5ILY A;  5E8L A;  3TFV A;  3WE9 A;  1HM4 A;  2E8V A;  3PH7 A;  5IKH A;  1WKZ A;  4MC8 A;  1VG7 A;  3LDW A;  2QIS A;  3UCA A;  5AFX A;  2OGD A;  4Q23 A;  3IPI A;  1YYT A;  3RMG A;  2AEL A;  2F89 F;  3ZL6 A;  4DXJ A;  1YYR A;  4RXD A;  3WEK A;  4LZ0 A;  3WCC A;  5JV2 F;  1HXA A;  1VG6 A;  3LEE A;  1YHM A;  1DGP A;  5IK9 A;  3KBK A;  3KRC B;  4JVJ F;  4NKF A;  1JFG A;  5HN9 A;  2FTZ A;  1JFA A;  2PS8 A;  4MC0 A;  2I19 A;  3WEJ A;  2AZL A;  2F8C F;  1RQJ A;  1YYQ A;  2Q9Z A;  3ID0 A;  1YYU A;  5KSX F;  3TFN A;  3CKE A;  4NUA A;  5B0J A;  3Q2Q A;  5ILZ A;  5DGN F;  2E90 A;  3PYA A;  3DYH A;  4LZ3 A;  3WJK A;  3N1W F;  4NFI F;  4K10 A;  1VG3 A;  3N3D A;  3NPR A;  5B03 A;  2E94 A;  4GP2 A;  3OAC A;  2E91 A;  2J5C A;  5HN8 A;  2AZK A;  3WCA A;  3P5R A;  2E8W A;  4NKE A;  5JUZ F;  4F62 A;  4MC3 A;  1N24 A;  5DZ2 A;  1YJ4 A;  5A0I A;  3ICN A;  2FOR A;  4GP1 A;  5B0K A;  3KRA B;  4LFV F;  5IK6 A;  5IMN A;  3WEI A;  2E4O A;  5B02 A;  4LFG A;  4OMG A;  1N1B A;  3ICZ A;  3LZ9 A;  4KQS A;  4DZW A;  4RXA A;  3KRF B;  5A0J A;  3M02 A;  3TC1 A;  5ERO A;  5B01 A;  3RYW A;  3ICM A;  2Z4V A;  3DYG A;  3SDU A;  2ONG A;  3KRO B;  3V1X A;  1KIY A;  3LJI A;  1EZF A;  2PS6 A;  3AQ0 A;  1RTR A;  2F94 F;  3VJD A;  3ICK A;  3QKC A;  2F8Z F;  2Q58 A;  2ZCS A;  4LZC A;  4JZB A;  4EA1 A;  5DJP F;  5ER8 A;  5ILH A;  5ERM A;  3LGZ B;  3DYF A;  3WCE A;  1YV5 A;  4DWG A;  3KB9 A;  5IMP A;  3PKO A;  1WY0 A;  4KFA A;  3EZ3 A;  4OMH A;  3RBM A;  1RQI A;  3OYR A;  2ZCQ A;  3G4F A;  3OAB B;  3KRC A;  4N9U A;  5CG5 A;  1V4E A;  4KPD A;  3SDQ A;  3VJA A;  3IBA A;  1YQ7 A;  5HNA A;  1VG2 A;  3N45 F;  1V4K A;  2AEK A;  3PDE A;  3N0F A;  5IM1 A;  3WCJ A;  2Q9Y A;  3N49 F;  2ZEV A;  4GA3 A;  4LUU A;  5JV0 F;  4JZX A;  2EWG A;  5EAT A;  3EFQ A;  3ADZ A;  2Z7I A;  4XQS F;  3WCG A;  4RNQ A;  2ONH A;  4NG6 A;  3VJB A;  3S9V A;  2F92 F;  3KRP A;  4QXS F;  5IKA A;  1UBX A;  3QQV A;  2RAH A;  1N23 A;  3P8R A;  3Q1O A;  5DGM F;  3Q30 A;  4E9U A;  5DW7 A;  5AEL A;  2DH4 A;  4LPH F;  4P0W A;  3ZCD A;  1V4J A; 
#chains in the Genus database with same CATH homology
 5IN8 A;  4DEM F;  2Q80 A;  2J1O A;  1V4I A;  1PS1 A;  2VF6 A;  2Z4W A;  4KQ5 A;  1N1Z A;  5IL3 A;  4RYP A;  4LLS A;  1WL3 A;  2OPN A;  3P8L A;  3NF2 A;  3NPK A;  4XQR F;  1WL0 A;  3KRF A;  4FJQ A;  2PS4 A;  2E8T A;  2Z52 A;  2Z7H A;  4LLT A;  1ZW5 A;  2Z4X A;  4LIX A;  4JXN A;  3MZV A;  3KRO A;  3LSN A;  3N6K F;  1N22 A;  3G4D A;  3WJO A;  3VJC A;  2E8U A;  4LFE A;  4P0X A;  4LOB A;  3WCH A;  3N3L F;  3M01 A;  3SDV A;  3CC9 A;  4XQT F;  3OAC B;  4NFJ F;  3VJE A;  3WCI A;  4WK5 A;  1KIZ A;  4H5C F;  5DHK A;  5ILD A;  4UMJ A;  4DHD A;  4LTV A;  1V4H A;  4PVY F;  4KKM A;  2E92 A;  5E8K A;  5DJR F;  2PS7 A;  3VJ9 A;  3LK5 A;  5EAS A;  1WL1 A;  3WCL A;  3N0G A;  3WSA A;  1UBV A;  5HN7 A;  5DIQ F;  3N46 F;  2Z4Y A;  2E93 A;  2ZEU A;  4QPF A;  3WSB A;  4KVW A;  5CG6 A;  5ILJ A;  1HX9 A;  2AZJ A;  3EGT A;  4EA0 A;  2OA6 A;  4OKM A;  3M9U A;  1YHL A;  4LPG F;  3ZMB A;  5ILI A;  2E8X A;  1UBW A;  4NFK F;  3WJN A;  4EA2 A;  3B7L A;  2F9K F;  3MAV A;  2ZCR A;  5ILK A;  3RYE A;  3M00 A;  5JA0 F;  5AHU B;  1UBY A;  3LGK A;  5IVG A;  3VJ8 A;  4LXW A;  3TFP A;  3WCF A;  3ASX A;  3SAE A;  3WCD A;  3WCM A;  2Z78 A;  3P41 A;  1WMW A;  3BNX A;  4DWB A;  3APZ A;  3N1V F;  3WEG A;  4KWD A;  1HXC A;  3WCB A;  4E9Z A;  3WEF A;  4KVD A;  4RXE A;  4P0V A;  4H5D F;  3SDT A;  2H8O A;  5DHI A;  5DJV F;  3BNY A;  3N5H F;  3AQB B;  3CP6 A;  3ZOU A;  2ZCO A;  5IMI A;  3SDR A;  3ACX A;  4LTZ A;  5AYP A;  2OPM A;  1N20 A;  5B0I A;  3S4J A;  1FPS A;  3KRA A;  5EAU A;  3AE0 A;  2Z4Z A;  5A0K A;  1WL2 A;  4DI5 A;  3ZMC A;  3LOM A;  3Q2Z A;  4JYX A;  2E95 A;  3PYB A;  4ZQ8 A;  4N1Z F;  3V1V A;  3NRI A;  2Z50 A;  3P5P A;  3KRP B;  4F6X A;  1HM7 A;  4RXC A;  5DGS F;  4H5E F;  4LA6 A;  4F6V A;  3LMD A;  4LA5 A;  4OGU A;  3WEH A;  4HD1 A;  2F7M F;  3AQC B;  3M0G A;  3WC9 A;  5B0L A;  4E1E A;  1N21 A;  2O1O A;  5IL8 A;  3TS7 A;  4KQU A;  3ACW A;  5B0M A;  5C05 A;  1YHK A;  4KPJ A;  5JV1 F;  2J1P A;  2P1C A;  3LG5 A;  4KVY A;  1DI1 A;  4PVX F;  3W7F A;  5ERN A;  3V66 A;  1VG4 A;  4OKZ A;  2AET A;  1HXG A;  5I1U A;  1YYS A;  5H9D A;  5IK0 A;  2PS5 A;  3LLW A;  4KUX A;  3ACY A;  3OAB A;  5B00 A;  4GAX A;  4KK2 A;  2ZY1 A;  4FP4 A;  4KVI A;  4JXY A;  3N5J F;  4L2X F;  5E8H A;  3LVS A;  5ILY A;  5E8L A;  3TFV A;  3WE9 A;  1HM4 A;  2E8V A;  3PH7 A;  5IKH A;  1WKZ A;  4MC8 A;  1VG7 A;  3LDW A;  2QIS A;  3UCA A;  5AFX A;  2OGD A;  4Q23 A;  3IPI A;  1YYT A;  3RMG A;  2AEL A;  2F89 F;  3ZL6 A;  4DXJ A;  1YYR A;  4RXD A;  3WEK A;  4LZ0 A;  3WCC A;  5JV2 F;  1HXA A;  1VG6 A;  3LEE A;  1YHM A;  1DGP A;  5IK9 A;  3KBK A;  3KRC B;  4JVJ F;  4NKF A;  1JFG A;  5HN9 A;  2FTZ A;  1JFA A;  2PS8 A;  4MC0 A;  2I19 A;  3WEJ A;  2AZL A;  2F8C F;  1RQJ A;  1YYQ A;  2Q9Z A;  3ID0 A;  1YYU A;  5KSX F;  3TFN A;  3CKE A;  4NUA A;  5B0J A;  3Q2Q A;  5ILZ A;  5DGN F;  2E90 A;  3PYA A;  3DYH A;  4LZ3 A;  3WJK A;  3N1W F;  4NFI F;  4K10 A;  1VG3 A;  3N3D A;  3NPR A;  5B03 A;  2E94 A;  4GP2 A;  3OAC A;  2E91 A;  2J5C A;  5HN8 A;  2AZK A;  3WCA A;  3P5R A;  2E8W A;  4NKE A;  5JUZ F;  4F62 A;  4MC3 A;  1N24 A;  5DZ2 A;  1YJ4 A;  5A0I A;  3ICN A;  2FOR A;  4GP1 A;  5B0K A;  3KRA B;  4LFV F;  5IK6 A;  5IMN A;  3WEI A;  2E4O A;  5B02 A;  4LFG A;  4OMG A;  1N1B A;  3ICZ A;  3LZ9 A;  4KQS A;  4DZW A;  4RXA A;  3KRF B;  5A0J A;  3M02 A;  3TC1 A;  5ERO A;  5B01 A;  3RYW A;  3ICM A;  2Z4V A;  3DYG A;  3SDU A;  2ONG A;  3KRO B;  3V1X A;  1KIY A;  3LJI A;  1EZF A;  2PS6 A;  3AQ0 A;  1RTR A;  2F94 F;  3VJD A;  3ICK A;  3QKC A;  2F8Z F;  2Q58 A;  2ZCS A;  4LZC A;  4JZB A;  4EA1 A;  5DJP F;  5ER8 A;  5ILH A;  5ERM A;  3LGZ B;  3DYF A;  3WCE A;  1YV5 A;  4DWG A;  3KB9 A;  5IMP A;  3PKO A;  1WY0 A;  4KFA A;  3EZ3 A;  4OMH A;  3RBM A;  1RQI A;  3OYR A;  2ZCQ A;  3G4F A;  3OAB B;  3KRC A;  4N9U A;  5CG5 A;  1V4E A;  4KPD A;  3SDQ A;  3VJA A;  3IBA A;  1YQ7 A;  5HNA A;  1VG2 A;  3N45 F;  1V4K A;  2AEK A;  3PDE A;  3N0F A;  5IM1 A;  3WCJ A;  2Q9Y A;  3N49 F;  2ZEV A;  4GA3 A;  4LUU A;  5JV0 F;  4JZX A;  2EWG A;  5EAT A;  3EFQ A;  3ADZ A;  2Z7I A;  4XQS F;  3WCG A;  4RNQ A;  2ONH A;  4NG6 A;  3VJB A;  3S9V A;  2F92 F;  3KRP A;  4QXS F;  5IKA A;  1UBX A;  3QQV A;  2RAH A;  1N23 A;  3P8R A;  3Q1O A;  5DGM F;  3Q30 A;  4E9U A;  5DW7 A;  5AEL A;  2DH4 A;  4LPH F;  4P0W A;  3ZCD A;  1V4J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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