1EZFA

Crystal structure of human squalene synthase
Total Genus 131
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
131
sequence length
333
structure length
323
Chain Sequence
NSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE
publication title Crystal structure of human squalene synthase. A key enzyme in cholesterol biosynthesis.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 131
structure length 323
sequence length 333
chains with identical sequence B, C
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2000-05-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 1ezfA00
4LPHF 1YQ7A 4QXSF 3PH7A 3V1VA 5IM1A 2Z4WA 5DGSF 1YYTA 1HX9A 3LEEA 4KVDA 5DGMF 1WL1A 3WCBA 3WJNA 2PS6A 5JV1F 3RBMA 4RXDA 5ILKA 4LLSA 3N0GA 5A0IA 1WKZA 3N5HF 2ONHA 2J1PA 3ICZA 5HN8A 4LOBA 3NF2A 3ID0A 3SAEA 4DWBA 5B0LA 4DI5A 5IMIA 4MC8A 3WCHA 2ZCOA 1EZFA 3LK5A 3LSNA 4QPFA 3M0GA 4E1EA 2Q9YA 5EROA 4WK5A 4LZ0A 3M00A 3DYGA 2AZKA 3ZCDA 4Q23A 4JZXA 2Z4VA 3WSAA 1N21A 3N5JF 2Q80A 3ASXA 3AQ0A 3KRAB 1RTRA 2Z52A 3N1VF 4PVXF 4MC3A 5C05A 3PYAA 3RMGA 4OKZA 3ICMA 5IL8A 3ADZA 3TFVA 3OACB 4NFIF 4P0VA 5DHKA 5AFXA 5EATA 3WCGA 5B00A 3NPKA 2E8TA 5ERMA 3Q2ZA 5IKAA 3WJKA 4LUUA 5DGNF 3KRAA 4NFKF 3PDEA 4RYPA 3P41A 3RYEA 2E8WA 3Q30A 3OACA 4KQ5A 3KB9A 1WL3A 2Z4YA 2AZJA 4KQSA 5DJPF 4KFAA 4KQUA 2Z7HA 2E4OA 3G4DA 5ILIA 3KRCB 4NG6A 3UCAA 2H8OA 3SDTA 3WSBA 5JUZF 4H5DF 4KVYA 2I19A 2O1OA 5HN7A 2RAHA 3P8LA 1WL2A 2ZCQA 1YHMA 3VJCA 1KIYA 2F8CF 4EA0A 5AELA 3N49F 4EA2A 3TS7A 2J5CA 3SDRA 1YHLA 4GAXA 3VJBA 2OPMA 1UBVA 5IVGA 3N1WF 4JZBA 1DI1A 4MC0A 5B0MA 3WJOA 3KRCA 2Z4ZA 3SDQA 4LA5A 5ER8A 4E9UA 5B0JA 3LZ9A 2QISA 3VJAA 1V4IA 4KVWA 2E94A 4OMHA 3BNXA 3KRFB 1PS1A 3EZ3A 3DYHA 4LLTA 3ZOUA 4LIXA 4DXJA 5B03A 3LG5A 4E9ZA 4KKMA 5IK6A 1UBWA 1ZW5A 3EGTA 3WEGA 4XQRF 3V1XA 1WL0A 5E8KA 1WMWA 4LZCA 3N3DA 3RYWA 3WC9A 2ZY1A 1RQJA 3WCCA 3ZMCA 1V4JA 3VJ9A 2FTZA 4OGUA 3LVSA 2VF6A 4KWDA 2AEKA 4P0WA 4FJQA 3KRFA 5A0JA 5DJVF 5ILZA 4LFGA 3WCIA 1DGPA 1V4KA 2E8UA 3B7LA 3AE0A 4N9UA 3TFNA 3WCDA 1N23A 4ZQ8A 3ACYA 4NUAA 2ZCRA 1N20A 4KPJA 3ACWA 2AETA 3LJIA 5EAUA 2EWGA 4LFVF 3KBKA 3WCAA 3LGZB 2F94F 5ERNA 5KSXF 5DJRF 1N1ZA 3ICKA 4RXCA 5A0KA 5JV2F 5ILDA 2E8VA 2E93A 2ZEVA 2F9KF 4N1ZF 2F92F 1VG3A 4LXWA 3W7FA 4JVJF 4LA6A 1KIZA 2ZCSA 5B0KA 1YYUA 4KUXA 3WEFA 3WEHA 3NRIA 3ICNA 3SDVA 2PS7A 4L2XF 5IK0A 5E8HA 3LDWA 3PYBA 3WCJA 4PVYF 2PS8A 5DIQF 4XQTF 4GP1A 2DH4A 3AQBB 4F6XA 5IN8A 5IL3A 4EA1A 1HXGA 4OMGA 2Z78A 1VG7A 1HXAA 2Q58A 5AYPA 2Z50A 5DZ2A 3Q1OA 3M9UA 4UMJA 2PS4A 5DHIA 5ILHA 2F7MF 1YJ4A 3VJ8A 3ZL6A 1RQIA 3IBAA 2F89F 3LLWA 5HN9A 5JV0F 3OABB 4DHDA 3KROB 2OGDA 3N3LF 5DW7A 2OA6A 3LOMA 5IKHA 5IK9A 5CG5A 5AHUB 1N22A 3LMDA 4RXEA 4LPGF 4H5CF 2AZLA 3G4FA 2ZEUA 4JXYA 4LFEA 4F62A 3ACXA 5B02A 4DEMF 3DYFA 1N1BA 4GP2A 3CP6A 2E92A 5HNAA 3WCLA 2AELA 1HM4A 4K10A 2Q9ZA 1UBXA 1YV5A 1HXCA 3VJDA 1FPSA 3N0FA 3N46F 4HD1A 5IMPA 4LTVA 1UBYA 3OABA 3KROA 3Q2QA 3VJEA 5B0IA 2E8XA 3P8RA 1JFGA 3QQVA 3S4JA 1YYSA 3APZA 3WCEA 1HM7A 1N24A 1YYRA 3BNYA 3N45F 2PS5A 2Z4XA 1WY0A 2OPNA 4DZWA 4KVIA 3KRPB 3OYRA 4KK2A 4NKFA 3N6KF 4JYXA 3MZVA 3V66A 3WCMA 3AQCB 4RNQA 2E90A 1V4EA 4NKEA 2E91A 1YYQA 3SDUA 4P0XA 4GA3A 5EASA 5ILYA 3WEJA 5ILJA 3EFQA 5I1UA 2F8ZF 4F6VA 1VG4A 4LZ3A 2FORA 3QKCA 4XQSF 3M01A 4FP4A 4NFJF 3S9VA 1V4HA 2E95A 1VG6A 2Z7IA 3ZMBA 5H9DA 3NPRA 1VG2A 3IPIA 3KRPA 4DWGA 3TFPA 3WEKA 3P5PA 5CG6A 5JA0F 4LTZA 5E8LA 3M02A 4KPDA 3WEIA 3CC9A 4OKMA 4JXNA 2ONGA 4RXAA 3TC1A 4H5EF 5IMNA 3LGKA 3CKEA 3PKOA 2P1CA 1JFAA 2J1OA 1YHKA 3P5RA 3WCFA 3MAVA 3WE9A 5B01A
chains in the Genus database with same CATH superfamily
4LPHF 1YQ7A 4QXSF 3PH7A 3V1VA 5IM1A 2Z4WA 5DGSF 1YYTA 1HX9A 3LEEA 4KVDA 5DGMF 1WL1A 3WCBA 3WJNA 2PS6A 5JV1F 3RBMA 4RXDA 5ILKA 4LLSA 3N0GA 5A0IA 1WKZA 3N5HF 2ONHA 2J1PA 3ICZA 5HN8A 4LOBA 3NF2A 3ID0A 3SAEA 4DWBA 5B0LA 4DI5A 5IMIA 4MC8A 3WCHA 2ZCOA 1EZFA 3LK5A 3LSNA 4QPFA 3M0GA 4E1EA 2Q9YA 5EROA 4WK5A 4LZ0A 3M00A 3DYGA 2AZKA 3ZCDA 4Q23A 4JZXA 2Z4VA 3WSAA 1N21A 3N5JF 2Q80A 3ASXA 3AQ0A 3KRAB 1RTRA 2Z52A 3N1VF 4PVXF 4MC3A 5C05A 3PYAA 3RMGA 4OKZA 3ICMA 5IL8A 3ADZA 3TFVA 3OACB 4NFIF 4P0VA 5DHKA 5AFXA 5EATA 3WCGA 5B00A 3NPKA 2E8TA 5ERMA 3Q2ZA 5IKAA 3WJKA 4LUUA 5DGNF 3KRAA 4NFKF 3PDEA 4RYPA 3P41A 3RYEA 2E8WA 3Q30A 3OACA 4KQ5A 3KB9A 1WL3A 2Z4YA 2AZJA 4KQSA 5DJPF 4KFAA 4KQUA 2Z7HA 2E4OA 3G4DA 5ILIA 3KRCB 4NG6A 3UCAA 2H8OA 3SDTA 3WSBA 5JUZF 4H5DF 4KVYA 2I19A 2O1OA 5HN7A 2RAHA 3P8LA 1WL2A 2ZCQA 1YHMA 3VJCA 1KIYA 2F8CF 4EA0A 5AELA 3N49F 4EA2A 3TS7A 2J5CA 3SDRA 1YHLA 4GAXA 3VJBA 2OPMA 1UBVA 5IVGA 3N1WF 4JZBA 1DI1A 4MC0A 5B0MA 3WJOA 3KRCA 2Z4ZA 3SDQA 4LA5A 5ER8A 4E9UA 5B0JA 3LZ9A 2QISA 3VJAA 1V4IA 4KVWA 2E94A 4OMHA 3BNXA 3KRFB 1PS1A 3EZ3A 3DYHA 4LLTA 3ZOUA 4LIXA 4DXJA 5B03A 3LG5A 4E9ZA 4KKMA 5IK6A 1UBWA 1ZW5A 3EGTA 3WEGA 4XQRF 3V1XA 1WL0A 5E8KA 1WMWA 4LZCA 3N3DA 3RYWA 3WC9A 2ZY1A 1RQJA 3WCCA 3ZMCA 1V4JA 3VJ9A 2FTZA 4OGUA 3LVSA 2VF6A 4KWDA 2AEKA 4P0WA 4FJQA 3KRFA 5A0JA 5DJVF 5ILZA 4LFGA 3WCIA 1DGPA 1V4KA 2E8UA 3B7LA 3AE0A 4N9UA 3TFNA 3WCDA 1N23A 4ZQ8A 3ACYA 4NUAA 2ZCRA 1N20A 4KPJA 3ACWA 2AETA 3LJIA 5EAUA 2EWGA 4LFVF 3KBKA 3WCAA 3LGZB 2F94F 5ERNA 5KSXF 5DJRF 1N1ZA 3ICKA 4RXCA 5A0KA 5JV2F 5ILDA 2E8VA 2E93A 2ZEVA 2F9KF 4N1ZF 2F92F 1VG3A 4LXWA 3W7FA 4JVJF 4LA6A 1KIZA 2ZCSA 5B0KA 1YYUA 4KUXA 3WEFA 3WEHA 3NRIA 3ICNA 3SDVA 2PS7A 4L2XF 5IK0A 5E8HA 3LDWA 3PYBA 3WCJA 4PVYF 2PS8A 5DIQF 4XQTF 4GP1A 2DH4A 3AQBB 4F6XA 5IN8A 5IL3A 4EA1A 1HXGA 4OMGA 2Z78A 1VG7A 1HXAA 2Q58A 5AYPA 2Z50A 5DZ2A 3Q1OA 3M9UA 4UMJA 2PS4A 5DHIA 5ILHA 2F7MF 1YJ4A 3VJ8A 3ZL6A 1RQIA 3IBAA 2F89F 3LLWA 5HN9A 5JV0F 3OABB 4DHDA 3KROB 2OGDA 3N3LF 5DW7A 2OA6A 3LOMA 5IKHA 5IK9A 5CG5A 5AHUB 1N22A 3LMDA 4RXEA 4LPGF 4H5CF 2AZLA 3G4FA 2ZEUA 4JXYA 4LFEA 4F62A 3ACXA 5B02A 4DEMF 3DYFA 1N1BA 4GP2A 3CP6A 2E92A 5HNAA 3WCLA 2AELA 1HM4A 4K10A 2Q9ZA 1UBXA 1YV5A 1HXCA 3VJDA 1FPSA 3N0FA 3N46F 4HD1A 5IMPA 4LTVA 1UBYA 3OABA 3KROA 3Q2QA 3VJEA 5B0IA 2E8XA 3P8RA 1JFGA 3QQVA 3S4JA 1YYSA 3APZA 3WCEA 1HM7A 1N24A 1YYRA 3BNYA 3N45F 2PS5A 2Z4XA 1WY0A 2OPNA 4DZWA 4KVIA 3KRPB 3OYRA 4KK2A 4NKFA 3N6KF 4JYXA 3MZVA 3V66A 3WCMA 3AQCB 4RNQA 2E90A 1V4EA 4NKEA 2E91A 1YYQA 3SDUA 4P0XA 4GA3A 5EASA 5ILYA 3WEJA 5ILJA 3EFQA 5I1UA 2F8ZF 4F6VA 1VG4A 4LZ3A 2FORA 3QKCA 4XQSF 3M01A 4FP4A 4NFJF 3S9VA 1V4HA 2E95A 1VG6A 2Z7IA 3ZMBA 5H9DA 3NPRA 1VG2A 3IPIA 3KRPA 4DWGA 3TFPA 3WEKA 3P5PA 5CG6A 5JA0F 4LTZA 5E8LA 3M02A 4KPDA 3WEIA 3CC9A 4OKMA 4JXNA 2ONGA 4RXAA 3TC1A 4H5EF 5IMNA 3LGKA 3CKEA 3PKOA 2P1CA 1JFAA 2J1OA 1YHKA 3P5RA 3WCFA 3MAVA 3WE9A 5B01A
chains in the Genus database with same CATH topology
4LPHF 1YQ7A 4QXSF 3PH7A 3V1VA 5IM1A 2Z4WA 5DGSF 1YYTA 1HX9A 3LEEA 4KVDA 5DGMF 1WL1A 3WCBA 3WJNA 2PS6A 5JV1F 3RBMA 4RXDA 5ILKA 4LLSA 3N0GA 5A0IA 1WKZA 3N5HF 2ONHA 2J1PA 3ICZA 5HN8A 4LOBA 3NF2A 3ID0A 3SAEA 4DWBA 5B0LA 4DI5A 5IMIA 4MC8A 3WCHA 2ZCOA 1EZFA 3LK5A 3LSNA 4QPFA 3M0GA 4E1EA 2Q9YA 5EROA 4WK5A 4LZ0A 3M00A 3DYGA 2AZKA 3ZCDA 4Q23A 4JZXA 2Z4VA 3WSAA 1N21A 3N5JF 2Q80A 3ASXA 3AQ0A 3KRAB 1RTRA 2Z52A 3N1VF 4PVXF 4MC3A 5C05A 3PYAA 3RMGA 4OKZA 3ICMA 5IL8A 3ADZA 3TFVA 3OACB 4NFIF 4P0VA 5DHKA 5AFXA 5EATA 3WCGA 5B00A 3NPKA 2E8TA 5ERMA 3Q2ZA 5IKAA 3WJKA 4LUUA 5DGNF 3KRAA 4NFKF 3PDEA 4RYPA 3P41A 3RYEA 2E8WA 3Q30A 3OACA 4KQ5A 3KB9A 1WL3A 2Z4YA 2AZJA 4KQSA 5DJPF 4KFAA 4KQUA 2Z7HA 2E4OA 3G4DA 5ILIA 3KRCB 4NG6A 3UCAA 2H8OA 3SDTA 3WSBA 5JUZF 4H5DF 4KVYA 2I19A 2O1OA 5HN7A 2RAHA 3P8LA 1WL2A 2ZCQA 1YHMA 3VJCA 1KIYA 2F8CF 4EA0A 5AELA 3N49F 4EA2A 3TS7A 2J5CA 3SDRA 1YHLA 4GAXA 3VJBA 2OPMA 1UBVA 5IVGA 3N1WF 4JZBA 1DI1A 4MC0A 5B0MA 3WJOA 3KRCA 2Z4ZA 3SDQA 4LA5A 5ER8A 4E9UA 5B0JA 3LZ9A 2QISA 3VJAA 1V4IA 4KVWA 2E94A 4OMHA 3BNXA 3KRFB 1PS1A 3EZ3A 3DYHA 4LLTA 3ZOUA 4LIXA 4DXJA 5B03A 3LG5A 4E9ZA 4KKMA 5IK6A 1UBWA 1ZW5A 3EGTA 3WEGA 4XQRF 3V1XA 1WL0A 5E8KA 1WMWA 4LZCA 3N3DA 3RYWA 3WC9A 2ZY1A 1RQJA 3WCCA 3ZMCA 1V4JA 3VJ9A 2FTZA 4OGUA 3LVSA 2VF6A 4KWDA 2AEKA 4P0WA 4FJQA 3KRFA 5A0JA 5DJVF 5ILZA 4LFGA 3WCIA 1DGPA 1V4KA 2E8UA 3B7LA 3AE0A 4N9UA 3TFNA 3WCDA 1N23A 4ZQ8A 3ACYA 4NUAA 2ZCRA 1N20A 4KPJA 3ACWA 2AETA 3LJIA 5EAUA 2EWGA 4LFVF 3KBKA 3WCAA 3LGZB 2F94F 5ERNA 5KSXF 5DJRF 1N1ZA 3ICKA 4RXCA 5A0KA 5JV2F 5ILDA 2E8VA 2E93A 2ZEVA 2F9KF 4N1ZF 2F92F 1VG3A 4LXWA 3W7FA 4JVJF 4LA6A 1KIZA 2ZCSA 5B0KA 1YYUA 4KUXA 3WEFA 3WEHA 3NRIA 3ICNA 3SDVA 2PS7A 4L2XF 5IK0A 5E8HA 3LDWA 3PYBA 3WCJA 4PVYF 2PS8A 5DIQF 4XQTF 4GP1A 2DH4A 3AQBB 4F6XA 5IN8A 5IL3A 4EA1A 1HXGA 4OMGA 2Z78A 1VG7A 1HXAA 2Q58A 5AYPA 2Z50A 5DZ2A 3Q1OA 3M9UA 4UMJA 2PS4A 5DHIA 5ILHA 2F7MF 1YJ4A 3VJ8A 3ZL6A 1RQIA 3IBAA 2F89F 3LLWA 5HN9A 5JV0F 3OABB 4DHDA 3KROB 2OGDA 3N3LF 5DW7A 2OA6A 3LOMA 5IKHA 5IK9A 5CG5A 5AHUB 1N22A 3LMDA 4RXEA 4LPGF 4H5CF 2AZLA 3G4FA 2ZEUA 4JXYA 4LFEA 4F62A 3ACXA 5B02A 4DEMF 3DYFA 1N1BA 4GP2A 3CP6A 2E92A 5HNAA 3WCLA 2AELA 1HM4A 4K10A 2Q9ZA 1UBXA 1YV5A 1HXCA 3VJDA 1FPSA 3N0FA 3N46F 4HD1A 5IMPA 4LTVA 1UBYA 3OABA 3KROA 3Q2QA 3VJEA 5B0IA 2E8XA 3P8RA 1JFGA 3QQVA 3S4JA 1YYSA 3APZA 3WCEA 1HM7A 1N24A 1YYRA 3BNYA 3N45F 2PS5A 2Z4XA 1WY0A 2OPNA 4DZWA 4KVIA 3KRPB 3OYRA 4KK2A 4NKFA 3N6KF 4JYXA 3MZVA 3V66A 3WCMA 3AQCB 4RNQA 2E90A 1V4EA 4NKEA 2E91A 1YYQA 3SDUA 4P0XA 4GA3A 5EASA 5ILYA 3WEJA 5ILJA 3EFQA 5I1UA 2F8ZF 4F6VA 1VG4A 4LZ3A 2FORA 3QKCA 4XQSF 3M01A 4FP4A 4NFJF 3S9VA 1V4HA 2E95A 1VG6A 2Z7IA 3ZMBA 5H9DA 3NPRA 1VG2A 3IPIA 3KRPA 4DWGA 3TFPA 3WEKA 3P5PA 5CG6A 5JA0F 4LTZA 5E8LA 3M02A 4KPDA 3WEIA 3CC9A 4OKMA 4JXNA 2ONGA 4RXAA 3TC1A 4H5EF 5IMNA 3LGKA 3CKEA 3PKOA 2P1CA 1JFAA 2J1OA 1YHKA 3P5RA 3WCFA 3MAVA 3WE9A 5B01A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LPH F;  1YQ7 A;  4QXS F;  3PH7 A;  3V1V A;  5IM1 A;  2Z4W A;  5DGS F;  1YYT A;  1HX9 A;  3LEE A;  4KVD A;  5DGM F;  1WL1 A;  3WCB A;  3WJN A;  2PS6 A;  5JV1 F;  3RBM A;  4RXD A;  5ILK A;  4LLS A;  3N0G A;  5A0I A;  1WKZ A;  3N5H F;  2ONH A;  2J1P A;  3ICZ A;  5HN8 A;  4LOB A;  3NF2 A;  3ID0 A;  3SAE A;  4DWB A;  5B0L A;  4DI5 A;  5IMI A;  4MC8 A;  3WCH A;  2ZCO A;  1EZF A;  3LK5 A;  3LSN A;  4QPF A;  3M0G A;  4E1E A;  2Q9Y A;  5ERO A;  4WK5 A;  4LZ0 A;  3M00 A;  3DYG A;  2AZK A;  3ZCD A;  4Q23 A;  4JZX A;  2Z4V A;  3WSA A;  1N21 A;  3N5J F;  2Q80 A;  3ASX A;  3AQ0 A;  3KRA B;  1RTR A;  2Z52 A;  3N1V F;  4PVX F;  4MC3 A;  5C05 A;  3PYA A;  3RMG A;  4OKZ A;  3ICM A;  5IL8 A;  3ADZ A;  3TFV A;  3OAC B;  4NFI F;  4P0V A;  5DHK A;  5AFX A;  5EAT A;  3WCG A;  5B00 A;  3NPK A;  2E8T A;  5ERM A;  3Q2Z A;  5IKA A;  3WJK A;  4LUU A;  5DGN F;  3KRA A;  4NFK F;  3PDE A;  4RYP A;  3P41 A;  3RYE A;  2E8W A;  3Q30 A;  3OAC A;  4KQ5 A;  3KB9 A;  1WL3 A;  2Z4Y A;  2AZJ A;  4KQS A;  5DJP F;  4KFA A;  4KQU A;  2Z7H A;  2E4O A;  3G4D A;  5ILI A;  3KRC B;  4NG6 A;  3UCA A;  2H8O A;  3SDT A;  3WSB A;  5JUZ F;  4H5D F;  4KVY A;  2I19 A;  2O1O A;  5HN7 A;  2RAH A;  3P8L A;  1WL2 A;  2ZCQ A;  1YHM A;  3VJC A;  1KIY A;  2F8C F;  4EA0 A;  5AEL A;  3N49 F;  4EA2 A;  3TS7 A;  2J5C A;  3SDR A;  1YHL A;  4GAX A;  3VJB A;  2OPM A;  1UBV A;  5IVG A;  3N1W F;  4JZB A;  1DI1 A;  4MC0 A;  5B0M A;  3WJO A;  3KRC A;  2Z4Z A;  3SDQ A;  4LA5 A;  5ER8 A;  4E9U A;  5B0J A;  3LZ9 A;  2QIS A;  3VJA A;  1V4I A;  4KVW A;  2E94 A;  4OMH A;  3BNX A;  3KRF B;  1PS1 A;  3EZ3 A;  3DYH A;  4LLT A;  3ZOU A;  4LIX A;  4DXJ A;  5B03 A;  3LG5 A;  4E9Z A;  4KKM A;  5IK6 A;  1UBW A;  1ZW5 A;  3EGT A;  3WEG A;  4XQR F;  3V1X A;  1WL0 A;  5E8K A;  1WMW A;  4LZC A;  3N3D A;  3RYW A;  3WC9 A;  2ZY1 A;  1RQJ A;  3WCC A;  3ZMC A;  1V4J A;  3VJ9 A;  2FTZ A;  4OGU A;  3LVS A;  2VF6 A;  4KWD A;  2AEK A;  4P0W A;  4FJQ A;  3KRF A;  5A0J A;  5DJV F;  5ILZ A;  4LFG A;  3WCI A;  1DGP A;  1V4K A;  2E8U A;  3B7L A;  3AE0 A;  4N9U A;  3TFN A;  3WCD A;  1N23 A;  4ZQ8 A;  3ACY A;  4NUA A;  2ZCR A;  1N20 A;  4KPJ A;  3ACW A;  2AET A;  3LJI A;  5EAU A;  2EWG A;  4LFV F;  3KBK A;  3WCA A;  3LGZ B;  2F94 F;  5ERN A;  5KSX F;  5DJR F;  1N1Z A;  3ICK A;  4RXC A;  5A0K A;  5JV2 F;  5ILD A;  2E8V A;  2E93 A;  2ZEV A;  2F9K F;  4N1Z F;  2F92 F;  1VG3 A;  4LXW A;  3W7F A;  4JVJ F;  4LA6 A;  1KIZ A;  2ZCS A;  5B0K A;  1YYU A;  4KUX A;  3WEF A;  3WEH A;  3NRI A;  3ICN A;  3SDV A;  2PS7 A;  4L2X F;  5IK0 A;  5E8H A;  3LDW A;  3PYB A;  3WCJ A;  4PVY F;  2PS8 A;  5DIQ F;  4XQT F;  4GP1 A;  2DH4 A;  3AQB B;  4F6X A;  5IN8 A;  5IL3 A;  4EA1 A;  1HXG A;  4OMG A;  2Z78 A;  1VG7 A;  1HXA A;  2Q58 A;  5AYP A;  2Z50 A;  5DZ2 A;  3Q1O A;  3M9U A;  4UMJ A;  2PS4 A;  5DHI A;  5ILH A;  2F7M F;  1YJ4 A;  3VJ8 A;  3ZL6 A;  1RQI A;  3IBA A;  2F89 F;  3LLW A;  5HN9 A;  5JV0 F;  3OAB B;  4DHD A;  3KRO B;  2OGD A;  3N3L F;  5DW7 A;  2OA6 A;  3LOM A;  5IKH A;  5IK9 A;  5CG5 A;  5AHU B;  1N22 A;  3LMD A;  4RXE A;  4LPG F;  4H5C F;  2AZL A;  3G4F A;  2ZEU A;  4JXY A;  4LFE A;  4F62 A;  3ACX A;  5B02 A;  4DEM F;  3DYF A;  1N1B A;  4GP2 A;  3CP6 A;  2E92 A;  5HNA A;  3WCL A;  2AEL A;  1HM4 A;  4K10 A;  2Q9Z A;  1UBX A;  1YV5 A;  1HXC A;  3VJD A;  1FPS A;  3N0F A;  3N46 F;  4HD1 A;  5IMP A;  4LTV A;  1UBY A;  3OAB A;  3KRO A;  3Q2Q A;  3VJE A;  5B0I A;  2E8X A;  3P8R A;  1JFG A;  3QQV A;  3S4J A;  1YYS A;  3APZ A;  3WCE A;  1HM7 A;  1N24 A;  1YYR A;  3BNY A;  3N45 F;  2PS5 A;  2Z4X A;  1WY0 A;  2OPN A;  4DZW A;  4KVI A;  3KRP B;  3OYR A;  4KK2 A;  4NKF A;  3N6K F;  4JYX A;  3MZV A;  3V66 A;  3WCM A;  3AQC B;  4RNQ A;  2E90 A;  1V4E A;  4NKE A;  2E91 A;  1YYQ A;  3SDU A;  4P0X A;  4GA3 A;  5EAS A;  5ILY A;  3WEJ A;  5ILJ A;  3EFQ A;  5I1U A;  2F8Z F;  4F6V A;  1VG4 A;  4LZ3 A;  2FOR A;  3QKC A;  4XQS F;  3M01 A;  4FP4 A;  4NFJ F;  3S9V A;  1V4H A;  2E95 A;  1VG6 A;  2Z7I A;  3ZMB A;  5H9D A;  3NPR A;  1VG2 A;  3IPI A;  3KRP A;  4DWG A;  3TFP A;  3WEK A;  3P5P A;  5CG6 A;  5JA0 F;  4LTZ A;  5E8L A;  3M02 A;  4KPD A;  3WEI A;  3CC9 A;  4OKM A;  4JXN A;  2ONG A;  4RXA A;  3TC1 A;  4H5E F;  5IMN A;  3LGK A;  3CKE A;  3PKO A;  2P1C A;  1JFA A;  2J1O A;  1YHK A;  3P5R A;  3WCF A;  3MAV A;  3WE9 A;  5B01 A; 
#chains in the Genus database with same CATH topology
 4LPH F;  1YQ7 A;  4QXS F;  3PH7 A;  3V1V A;  5IM1 A;  2Z4W A;  5DGS F;  1YYT A;  1HX9 A;  3LEE A;  4KVD A;  5DGM F;  1WL1 A;  3WCB A;  3WJN A;  2PS6 A;  5JV1 F;  3RBM A;  4RXD A;  5ILK A;  4LLS A;  3N0G A;  5A0I A;  1WKZ A;  3N5H F;  2ONH A;  2J1P A;  3ICZ A;  5HN8 A;  4LOB A;  3NF2 A;  3ID0 A;  3SAE A;  4DWB A;  5B0L A;  4DI5 A;  5IMI A;  4MC8 A;  3WCH A;  2ZCO A;  1EZF A;  3LK5 A;  3LSN A;  4QPF A;  3M0G A;  4E1E A;  2Q9Y A;  5ERO A;  4WK5 A;  4LZ0 A;  3M00 A;  3DYG A;  2AZK A;  3ZCD A;  4Q23 A;  4JZX A;  2Z4V A;  3WSA A;  1N21 A;  3N5J F;  2Q80 A;  3ASX A;  3AQ0 A;  3KRA B;  1RTR A;  2Z52 A;  3N1V F;  4PVX F;  4MC3 A;  5C05 A;  3PYA A;  3RMG A;  4OKZ A;  3ICM A;  5IL8 A;  3ADZ A;  3TFV A;  3OAC B;  4NFI F;  4P0V A;  5DHK A;  5AFX A;  5EAT A;  3WCG A;  5B00 A;  3NPK A;  2E8T A;  5ERM A;  3Q2Z A;  5IKA A;  3WJK A;  4LUU A;  5DGN F;  3KRA A;  4NFK F;  3PDE A;  4RYP A;  3P41 A;  3RYE A;  2E8W A;  3Q30 A;  3OAC A;  4KQ5 A;  3KB9 A;  1WL3 A;  2Z4Y A;  2AZJ A;  4KQS A;  5DJP F;  4KFA A;  4KQU A;  2Z7H A;  2E4O A;  3G4D A;  5ILI A;  3KRC B;  4NG6 A;  3UCA A;  2H8O A;  3SDT A;  3WSB A;  5JUZ F;  4H5D F;  4KVY A;  2I19 A;  2O1O A;  5HN7 A;  2RAH A;  3P8L A;  1WL2 A;  2ZCQ A;  1YHM A;  3VJC A;  1KIY A;  2F8C F;  4EA0 A;  5AEL A;  3N49 F;  4EA2 A;  3TS7 A;  2J5C A;  3SDR A;  1YHL A;  4GAX A;  3VJB A;  2OPM A;  1UBV A;  5IVG A;  3N1W F;  4JZB A;  1DI1 A;  4MC0 A;  5B0M A;  3WJO A;  3KRC A;  2Z4Z A;  3SDQ A;  4LA5 A;  5ER8 A;  4E9U A;  5B0J A;  3LZ9 A;  2QIS A;  3VJA A;  1V4I A;  4KVW A;  2E94 A;  4OMH A;  3BNX A;  3KRF B;  1PS1 A;  3EZ3 A;  3DYH A;  4LLT A;  3ZOU A;  4LIX A;  4DXJ A;  5B03 A;  3LG5 A;  4E9Z A;  4KKM A;  5IK6 A;  1UBW A;  1ZW5 A;  3EGT A;  3WEG A;  4XQR F;  3V1X A;  1WL0 A;  5E8K A;  1WMW A;  4LZC A;  3N3D A;  3RYW A;  3WC9 A;  2ZY1 A;  1RQJ A;  3WCC A;  3ZMC A;  1V4J A;  3VJ9 A;  2FTZ A;  4OGU A;  3LVS A;  2VF6 A;  4KWD A;  2AEK A;  4P0W A;  4FJQ A;  3KRF A;  5A0J A;  5DJV F;  5ILZ A;  4LFG A;  3WCI A;  1DGP A;  1V4K A;  2E8U A;  3B7L A;  3AE0 A;  4N9U A;  3TFN A;  3WCD A;  1N23 A;  4ZQ8 A;  3ACY A;  4NUA A;  2ZCR A;  1N20 A;  4KPJ A;  3ACW A;  2AET A;  3LJI A;  5EAU A;  2EWG A;  4LFV F;  3KBK A;  3WCA A;  3LGZ B;  2F94 F;  5ERN A;  5KSX F;  5DJR F;  1N1Z A;  3ICK A;  4RXC A;  5A0K A;  5JV2 F;  5ILD A;  2E8V A;  2E93 A;  2ZEV A;  2F9K F;  4N1Z F;  2F92 F;  1VG3 A;  4LXW A;  3W7F A;  4JVJ F;  4LA6 A;  1KIZ A;  2ZCS A;  5B0K A;  1YYU A;  4KUX A;  3WEF A;  3WEH A;  3NRI A;  3ICN A;  3SDV A;  2PS7 A;  4L2X F;  5IK0 A;  5E8H A;  3LDW A;  3PYB A;  3WCJ A;  4PVY F;  2PS8 A;  5DIQ F;  4XQT F;  4GP1 A;  2DH4 A;  3AQB B;  4F6X A;  5IN8 A;  5IL3 A;  4EA1 A;  1HXG A;  4OMG A;  2Z78 A;  1VG7 A;  1HXA A;  2Q58 A;  5AYP A;  2Z50 A;  5DZ2 A;  3Q1O A;  3M9U A;  4UMJ A;  2PS4 A;  5DHI A;  5ILH A;  2F7M F;  1YJ4 A;  3VJ8 A;  3ZL6 A;  1RQI A;  3IBA A;  2F89 F;  3LLW A;  5HN9 A;  5JV0 F;  3OAB B;  4DHD A;  3KRO B;  2OGD A;  3N3L F;  5DW7 A;  2OA6 A;  3LOM A;  5IKH A;  5IK9 A;  5CG5 A;  5AHU B;  1N22 A;  3LMD A;  4RXE A;  4LPG F;  4H5C F;  2AZL A;  3G4F A;  2ZEU A;  4JXY A;  4LFE A;  4F62 A;  3ACX A;  5B02 A;  4DEM F;  3DYF A;  1N1B A;  4GP2 A;  3CP6 A;  2E92 A;  5HNA A;  3WCL A;  2AEL A;  1HM4 A;  4K10 A;  2Q9Z A;  1UBX A;  1YV5 A;  1HXC A;  3VJD A;  1FPS A;  3N0F A;  3N46 F;  4HD1 A;  5IMP A;  4LTV A;  1UBY A;  3OAB A;  3KRO A;  3Q2Q A;  3VJE A;  5B0I A;  2E8X A;  3P8R A;  1JFG A;  3QQV A;  3S4J A;  1YYS A;  3APZ A;  3WCE A;  1HM7 A;  1N24 A;  1YYR A;  3BNY A;  3N45 F;  2PS5 A;  2Z4X A;  1WY0 A;  2OPN A;  4DZW A;  4KVI A;  3KRP B;  3OYR A;  4KK2 A;  4NKF A;  3N6K F;  4JYX A;  3MZV A;  3V66 A;  3WCM A;  3AQC B;  4RNQ A;  2E90 A;  1V4E A;  4NKE A;  2E91 A;  1YYQ A;  3SDU A;  4P0X A;  4GA3 A;  5EAS A;  5ILY A;  3WEJ A;  5ILJ A;  3EFQ A;  5I1U A;  2F8Z F;  4F6V A;  1VG4 A;  4LZ3 A;  2FOR A;  3QKC A;  4XQS F;  3M01 A;  4FP4 A;  4NFJ F;  3S9V A;  1V4H A;  2E95 A;  1VG6 A;  2Z7I A;  3ZMB A;  5H9D A;  3NPR A;  1VG2 A;  3IPI A;  3KRP A;  4DWG A;  3TFP A;  3WEK A;  3P5P A;  5CG6 A;  5JA0 F;  4LTZ A;  5E8L A;  3M02 A;  4KPD A;  3WEI A;  3CC9 A;  4OKM A;  4JXN A;  2ONG A;  4RXA A;  3TC1 A;  4H5E F;  5IMN A;  3LGK A;  3CKE A;  3PKO A;  2P1C A;  1JFA A;  2J1O A;  1YHK A;  3P5R A;  3WCF A;  3MAV A;  3WE9 A;  5B01 A; 
#chains in the Genus database with same CATH homology
 4LPH F;  1YQ7 A;  4QXS F;  3PH7 A;  3V1V A;  5IM1 A;  2Z4W A;  5DGS F;  1YYT A;  1HX9 A;  3LEE A;  4KVD A;  5DGM F;  1WL1 A;  3WCB A;  3WJN A;  2PS6 A;  5JV1 F;  3RBM A;  4RXD A;  5ILK A;  4LLS A;  3N0G A;  5A0I A;  1WKZ A;  3N5H F;  2ONH A;  2J1P A;  3ICZ A;  5HN8 A;  4LOB A;  3NF2 A;  3ID0 A;  3SAE A;  4DWB A;  5B0L A;  4DI5 A;  5IMI A;  4MC8 A;  3WCH A;  2ZCO A;  1EZF A;  3LK5 A;  3LSN A;  4QPF A;  3M0G A;  4E1E A;  2Q9Y A;  5ERO A;  4WK5 A;  4LZ0 A;  3M00 A;  3DYG A;  2AZK A;  3ZCD A;  4Q23 A;  4JZX A;  2Z4V A;  3WSA A;  1N21 A;  3N5J F;  2Q80 A;  3ASX A;  3AQ0 A;  3KRA B;  1RTR A;  2Z52 A;  3N1V F;  4PVX F;  4MC3 A;  5C05 A;  3PYA A;  3RMG A;  4OKZ A;  3ICM A;  5IL8 A;  3ADZ A;  3TFV A;  3OAC B;  4NFI F;  4P0V A;  5DHK A;  5AFX A;  5EAT A;  3WCG A;  5B00 A;  3NPK A;  2E8T A;  5ERM A;  3Q2Z A;  5IKA A;  3WJK A;  4LUU A;  5DGN F;  3KRA A;  4NFK F;  3PDE A;  4RYP A;  3P41 A;  3RYE A;  2E8W A;  3Q30 A;  3OAC A;  4KQ5 A;  3KB9 A;  1WL3 A;  2Z4Y A;  2AZJ A;  4KQS A;  5DJP F;  4KFA A;  4KQU A;  2Z7H A;  2E4O A;  3G4D A;  5ILI A;  3KRC B;  4NG6 A;  3UCA A;  2H8O A;  3SDT A;  3WSB A;  5JUZ F;  4H5D F;  4KVY A;  2I19 A;  2O1O A;  5HN7 A;  2RAH A;  3P8L A;  1WL2 A;  2ZCQ A;  1YHM A;  3VJC A;  1KIY A;  2F8C F;  4EA0 A;  5AEL A;  3N49 F;  4EA2 A;  3TS7 A;  2J5C A;  3SDR A;  1YHL A;  4GAX A;  3VJB A;  2OPM A;  1UBV A;  5IVG A;  3N1W F;  4JZB A;  1DI1 A;  4MC0 A;  5B0M A;  3WJO A;  3KRC A;  2Z4Z A;  3SDQ A;  4LA5 A;  5ER8 A;  4E9U A;  5B0J A;  3LZ9 A;  2QIS A;  3VJA A;  1V4I A;  4KVW A;  2E94 A;  4OMH A;  3BNX A;  3KRF B;  1PS1 A;  3EZ3 A;  3DYH A;  4LLT A;  3ZOU A;  4LIX A;  4DXJ A;  5B03 A;  3LG5 A;  4E9Z A;  4KKM A;  5IK6 A;  1UBW A;  1ZW5 A;  3EGT A;  3WEG A;  4XQR F;  3V1X A;  1WL0 A;  5E8K A;  1WMW A;  4LZC A;  3N3D A;  3RYW A;  3WC9 A;  2ZY1 A;  1RQJ A;  3WCC A;  3ZMC A;  1V4J A;  3VJ9 A;  2FTZ A;  4OGU A;  3LVS A;  2VF6 A;  4KWD A;  2AEK A;  4P0W A;  4FJQ A;  3KRF A;  5A0J A;  5DJV F;  5ILZ A;  4LFG A;  3WCI A;  1DGP A;  1V4K A;  2E8U A;  3B7L A;  3AE0 A;  4N9U A;  3TFN A;  3WCD A;  1N23 A;  4ZQ8 A;  3ACY A;  4NUA A;  2ZCR A;  1N20 A;  4KPJ A;  3ACW A;  2AET A;  3LJI A;  5EAU A;  2EWG A;  4LFV F;  3KBK A;  3WCA A;  3LGZ B;  2F94 F;  5ERN A;  5KSX F;  5DJR F;  1N1Z A;  3ICK A;  4RXC A;  5A0K A;  5JV2 F;  5ILD A;  2E8V A;  2E93 A;  2ZEV A;  2F9K F;  4N1Z F;  2F92 F;  1VG3 A;  4LXW A;  3W7F A;  4JVJ F;  4LA6 A;  1KIZ A;  2ZCS A;  5B0K A;  1YYU A;  4KUX A;  3WEF A;  3WEH A;  3NRI A;  3ICN A;  3SDV A;  2PS7 A;  4L2X F;  5IK0 A;  5E8H A;  3LDW A;  3PYB A;  3WCJ A;  4PVY F;  2PS8 A;  5DIQ F;  4XQT F;  4GP1 A;  2DH4 A;  3AQB B;  4F6X A;  5IN8 A;  5IL3 A;  4EA1 A;  1HXG A;  4OMG A;  2Z78 A;  1VG7 A;  1HXA A;  2Q58 A;  5AYP A;  2Z50 A;  5DZ2 A;  3Q1O A;  3M9U A;  4UMJ A;  2PS4 A;  5DHI A;  5ILH A;  2F7M F;  1YJ4 A;  3VJ8 A;  3ZL6 A;  1RQI A;  3IBA A;  2F89 F;  3LLW A;  5HN9 A;  5JV0 F;  3OAB B;  4DHD A;  3KRO B;  2OGD A;  3N3L F;  5DW7 A;  2OA6 A;  3LOM A;  5IKH A;  5IK9 A;  5CG5 A;  5AHU B;  1N22 A;  3LMD A;  4RXE A;  4LPG F;  4H5C F;  2AZL A;  3G4F A;  2ZEU A;  4JXY A;  4LFE A;  4F62 A;  3ACX A;  5B02 A;  4DEM F;  3DYF A;  1N1B A;  4GP2 A;  3CP6 A;  2E92 A;  5HNA A;  3WCL A;  2AEL A;  1HM4 A;  4K10 A;  2Q9Z A;  1UBX A;  1YV5 A;  1HXC A;  3VJD A;  1FPS A;  3N0F A;  3N46 F;  4HD1 A;  5IMP A;  4LTV A;  1UBY A;  3OAB A;  3KRO A;  3Q2Q A;  3VJE A;  5B0I A;  2E8X A;  3P8R A;  1JFG A;  3QQV A;  3S4J A;  1YYS A;  3APZ A;  3WCE A;  1HM7 A;  1N24 A;  1YYR A;  3BNY A;  3N45 F;  2PS5 A;  2Z4X A;  1WY0 A;  2OPN A;  4DZW A;  4KVI A;  3KRP B;  3OYR A;  4KK2 A;  4NKF A;  3N6K F;  4JYX A;  3MZV A;  3V66 A;  3WCM A;  3AQC B;  4RNQ A;  2E90 A;  1V4E A;  4NKE A;  2E91 A;  1YYQ A;  3SDU A;  4P0X A;  4GA3 A;  5EAS A;  5ILY A;  3WEJ A;  5ILJ A;  3EFQ A;  5I1U A;  2F8Z F;  4F6V A;  1VG4 A;  4LZ3 A;  2FOR A;  3QKC A;  4XQS F;  3M01 A;  4FP4 A;  4NFJ F;  3S9V A;  1V4H A;  2E95 A;  1VG6 A;  2Z7I A;  3ZMB A;  5H9D A;  3NPR A;  1VG2 A;  3IPI A;  3KRP A;  4DWG A;  3TFP A;  3WEK A;  3P5P A;  5CG6 A;  5JA0 F;  4LTZ A;  5E8L A;  3M02 A;  4KPD A;  3WEI A;  3CC9 A;  4OKM A;  4JXN A;  2ONG A;  4RXA A;  3TC1 A;  4H5E F;  5IMN A;  3LGK A;  3CKE A;  3PKO A;  2P1C A;  1JFA A;  2J1O A;  1YHK A;  3P5R A;  3WCF A;  3MAV A;  3WE9 A;  5B01 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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