2E92A

S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and bph-261
Total Genus 121
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
121
sequence length
304
structure length
291
Chain Sequence
NKMEAKIDELINNDPVWSSQNESLISKPYNHILLNFRLNLIVQINRVMNLPKDQLAIVSQIVELLHNSSLLIDDIEDNAPLRRGQTTSHLIFGVPSTINTANYMYFRAMQLVSQLTTKEPLYHNLITIFNEELINLHRGQGLDIYWRDFLPEIIPTQEMYLNMVMNKTGGLFRLTLRLMEALSPSLVPFINLLGIIYQIRDDYLNLKDFQMSGFAEDITEGKLSFPIVHALNFTKTKGQTEQHNEILRILLLRTSDKDIKLKLIQILEFDTNSLAYTKNFINQLVNMIKND
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords Geranylgeranyl pyrophosphate synthetase
publication title Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases
pubmed doi rcsb
source organism Saccharomyces cerevisiae
total genus 121
structure length 291
sequence length 304
chains with identical sequence B
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2007-01-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 2e92A00
3WSAA 4H5EF 3ACYA 1YYTA 3PKOA 2ZEVA 5C05A 5IK9A 5IMNA 3AQ0A 1N21A 4LTZA 4K10A 4MC8A 4KKMA 1WL1A 3MAVA 3VJCA 1JFGA 3EZ3A 5JV1F 3SDTA 4MC3A 2F9KF 3PYBA 3SDUA 4GAXA 5B03A 2E8XA 4N9UA 1VG4A 3PYAA 2E94A 1YV5A 3UCAA 1N22A 1DI1A 5ILYA 4Q23A 3ZL6A 5DGNF 3RMGA 5HNAA 2E95A 5CG5A 3TC1A 2ONGA 2E92A 1YHLA 5IKHA 2F8ZF 4WK5A 4H5CF 3KRPB 4LFVF 3WCDA 5ILZA 3WCEA 2DH4A 2ONHA 3WEJA 3N45F 3WSBA 3N46F 5B01A 2ZCQA 2QISA 3KROA 4F6XA 5E8HA 3B7LA 4JYXA 4KVIA 3AE0A 5ILKA 5DZ2A 4E9UA 3LGZB 3OABB 1N1ZA 2Z7IA 2ZEUA 3S4JA 3TS7A 5B0JA 2PS8A 2AELA 4JZBA 1UBWA 1HXAA 3NRIA 3PDEA 4LFEA 3SDVA 3LDWA 1JFAA 3P8LA 3WEHA 1UBYA 4KK2A 3WEIA 3WCJA 5E8LA 4LZ3A 5EAUA 4JXNA 4NKFA 1V4HA 3N5HF 3WJNA 5AHUB 3NF2A 3N5JF 3KB9A 4LZ0A 5EASA 3ZMCA 3WEFA 4EA1A 4XQSF 3P5PA 5DGSF 1RQIA 1HM4A 3KRCA 3RBMA 3ZMBA 5KSXF 3WCGA 3ACXA 3VJDA 3AQCB 4P0VA 3OACA 3WCFA 4NFIF 4NFKF 5B0LA 1PS1A 5DHKA 5DJRF 3P8RA 4DHDA 2F94F 5HN7A 5IVGA 4LFGA 4LXWA 3N1WF 3G4DA 4GP2A 4LTVA 4HD1A 4JVJF 3V1VA 2J5CA 2Z50A 3ASXA 4LA5A 4DWBA 2Q9YA 2OGDA 4KPJA 4NG6A 2Z4VA 4ZQ8A 3DYHA 4L2XF 3KRAB 3RYEA 3LG5A 5B00A 4KVDA 1YHKA 1HM7A 3ACWA 3NPKA 4DI5A 4OKMA 2FORA 2J1OA 5IM1A 4PVYF 3VJAA 1N20A 3CP6A 5IL3A 1YHMA 5B0MA 4E1EA 2OPMA 5AYPA 3NPRA 3ICZA 4F6VA 3RYWA 5IKAA 4LPGF 3TFPA 3ICMA 2E4OA 4NFJF 4FP4A 2Z7HA 4LLSA 3WEKA 1WL3A 4JZXA 4DWGA 3LZ9A 4RXDA 3VJ8A 4LIXA 5DJVF 2Z4WA 1VG7A 2E8TA 3KRPA 2VF6A 3IBAA 3N3DA 4RNQA 3CC9A 3LOMA 1V4IA 3N3LF 4LUUA 3WCBA 4NKEA 3LJIA 1V4JA 3OYRA 1VG2A 1YQ7A 2ZCOA 2OPNA 5HN9A 5E8KA 4OGUA 1DGPA 3OABA 5DGMF 2E8UA 1VG3A 1N23A 2ZCSA 1YYRA 3LEEA 4LZCA 2F7MF 1HXCA 3G4FA 3WCCA 4KPDA 2Z4ZA 3AQBB 3KRFA 5JV0F 5ILDA 3M0GA 4LPHF 1YYUA 3WEGA 4OMHA 4QXSF 4OMGA 2PS5A 5EROA 5IK0A 3VJ9A 3N6KF 5IN8A 3IPIA 4XQTF 3ID0A 3WJOA 5DHIA 3V66A 3PH7A 5A0KA 3DYGA 3ADZA 4KUXA 3P5RA 3LLWA 3WCHA 2Z4YA 2I19A 3CKEA 4DZWA 2Z52A 4KWDA 3KBKA 4OKZA 2Z78A 4QPFA 5B0IA 3OACB 4KQ5A 5ILHA 5JA0F 5ILIA 3M01A 5ERNA 3S9VA 3SDQA 4MC0A 5EATA 3Q30A 1WL0A 4PVXF 5I1UA 2F92F 4LOBA 3Q2ZA 1ZW5A 3N0FA 3WCMA 4N1ZF 1YYQA 3WC9A 4GP1A 3M00A 1EZFA 3VJEA 1N1BA 1N24A 3M9UA 1UBXA 4NUAA 1FPSA 3KRAA 4RXCA 4KFAA 2OA6A 2ZCRA 3MZVA 3WCAA 3SDRA 2F89F 5A0IA 5AELA 3ICKA 5IK6A 5CG6A 2E8VA 4F62A 3ICNA 5ERMA 5JUZF 4E9ZA 3N49F 5IMIA 2Q80A 1V4KA 5IL8A 3TFNA 3APZA 3QQVA 4DXJA 4FJQA 3LMDA 5B02A 1WL2A 2AETA 2RAHA 2AEKA 3EFQA 2H8OA 5HN8A 1HXGA 3KROB 5B0KA 3LK5A 2E93A 5DW7A 4H5DF 2ZY1A 5AFXA 3BNYA 4RXAA 3VJBA 4P0XA 3ZOUA 3LGKA 3TFVA 2E90A 4EA2A 3V1XA 1KIYA 3EGTA 3WCLA 2F8CF 1WKZA 2AZKA 2EWGA 4RXEA 5JV2F 3WJKA 2P1CA 2AZLA 4KVWA 2J1PA 2PS7A 3WE9A 3QKCA 5ILJA 3ZCDA 4XQRF 4DEMF 1HX9A 1V4EA 3BNXA 2O1OA 2Q9ZA 1RTRA 5DIQF 3SAEA 4P0WA 4UMJA 4LLTA 5H9DA 4RYPA 2Z4XA 3LSNA 2PS4A 4GA3A 3KRFB 3WCIA 3DYFA 4KQUA 5IMPA 2E91A 4KVYA 5A0JA 4JXYA 4KQSA 1YYSA 3M02A 5DJPF 1WY0A 1YJ4A 3Q1OA 3KRCB 1UBVA 3W7FA 2FTZA 3N0GA 2E8WA 5ER8A 1KIZA 4LA6A 3LVSA 3Q2QA 2Q58A 2PS6A 3N1VF 1RQJA 1WMWA 2AZJA 1VG6A 3P41A 4EA0A
chains in the Genus database with same CATH superfamily
3WSAA 4H5EF 3ACYA 1YYTA 3PKOA 2ZEVA 5C05A 5IK9A 5IMNA 3AQ0A 1N21A 4LTZA 4K10A 4MC8A 4KKMA 1WL1A 3MAVA 3VJCA 1JFGA 3EZ3A 5JV1F 3SDTA 4MC3A 2F9KF 3PYBA 3SDUA 4GAXA 5B03A 2E8XA 4N9UA 1VG4A 3PYAA 2E94A 1YV5A 3UCAA 1N22A 1DI1A 5ILYA 4Q23A 3ZL6A 5DGNF 3RMGA 5HNAA 2E95A 5CG5A 3TC1A 2ONGA 2E92A 1YHLA 5IKHA 2F8ZF 4WK5A 4H5CF 3KRPB 4LFVF 3WCDA 5ILZA 3WCEA 2DH4A 2ONHA 3WEJA 3N45F 3WSBA 3N46F 5B01A 2ZCQA 2QISA 3KROA 4F6XA 5E8HA 3B7LA 4JYXA 4KVIA 3AE0A 5ILKA 5DZ2A 4E9UA 3LGZB 3OABB 1N1ZA 2Z7IA 2ZEUA 3S4JA 3TS7A 5B0JA 2PS8A 2AELA 4JZBA 1UBWA 1HXAA 3NRIA 3PDEA 4LFEA 3SDVA 3LDWA 1JFAA 3P8LA 3WEHA 1UBYA 4KK2A 3WEIA 3WCJA 5E8LA 4LZ3A 5EAUA 4JXNA 4NKFA 1V4HA 3N5HF 3WJNA 5AHUB 3NF2A 3N5JF 3KB9A 4LZ0A 5EASA 3ZMCA 3WEFA 4EA1A 4XQSF 3P5PA 5DGSF 1RQIA 1HM4A 3KRCA 3RBMA 3ZMBA 5KSXF 3WCGA 3ACXA 3VJDA 3AQCB 4P0VA 3OACA 3WCFA 4NFIF 4NFKF 5B0LA 1PS1A 5DHKA 5DJRF 3P8RA 4DHDA 2F94F 5HN7A 5IVGA 4LFGA 4LXWA 3N1WF 3G4DA 4GP2A 4LTVA 4HD1A 4JVJF 3V1VA 2J5CA 2Z50A 3ASXA 4LA5A 4DWBA 2Q9YA 2OGDA 4KPJA 4NG6A 2Z4VA 4ZQ8A 3DYHA 4L2XF 3KRAB 3RYEA 3LG5A 5B00A 4KVDA 1YHKA 1HM7A 3ACWA 3NPKA 4DI5A 4OKMA 2FORA 2J1OA 5IM1A 4PVYF 3VJAA 1N20A 3CP6A 5IL3A 1YHMA 5B0MA 4E1EA 2OPMA 5AYPA 3NPRA 3ICZA 4F6VA 3RYWA 5IKAA 4LPGF 3TFPA 3ICMA 2E4OA 4NFJF 4FP4A 2Z7HA 4LLSA 3WEKA 1WL3A 4JZXA 4DWGA 3LZ9A 4RXDA 3VJ8A 4LIXA 5DJVF 2Z4WA 1VG7A 2E8TA 3KRPA 2VF6A 3IBAA 3N3DA 4RNQA 3CC9A 3LOMA 1V4IA 3N3LF 4LUUA 3WCBA 4NKEA 3LJIA 1V4JA 3OYRA 1VG2A 1YQ7A 2ZCOA 2OPNA 5HN9A 5E8KA 4OGUA 1DGPA 3OABA 5DGMF 2E8UA 1VG3A 1N23A 2ZCSA 1YYRA 3LEEA 4LZCA 2F7MF 1HXCA 3G4FA 3WCCA 4KPDA 2Z4ZA 3AQBB 3KRFA 5JV0F 5ILDA 3M0GA 4LPHF 1YYUA 3WEGA 4OMHA 4QXSF 4OMGA 2PS5A 5EROA 5IK0A 3VJ9A 3N6KF 5IN8A 3IPIA 4XQTF 3ID0A 3WJOA 5DHIA 3V66A 3PH7A 5A0KA 3DYGA 3ADZA 4KUXA 3P5RA 3LLWA 3WCHA 2Z4YA 2I19A 3CKEA 4DZWA 2Z52A 4KWDA 3KBKA 4OKZA 2Z78A 4QPFA 5B0IA 3OACB 4KQ5A 5ILHA 5JA0F 5ILIA 3M01A 5ERNA 3S9VA 3SDQA 4MC0A 5EATA 3Q30A 1WL0A 4PVXF 5I1UA 2F92F 4LOBA 3Q2ZA 1ZW5A 3N0FA 3WCMA 4N1ZF 1YYQA 3WC9A 4GP1A 3M00A 1EZFA 3VJEA 1N1BA 1N24A 3M9UA 1UBXA 4NUAA 1FPSA 3KRAA 4RXCA 4KFAA 2OA6A 2ZCRA 3MZVA 3WCAA 3SDRA 2F89F 5A0IA 5AELA 3ICKA 5IK6A 5CG6A 2E8VA 4F62A 3ICNA 5ERMA 5JUZF 4E9ZA 3N49F 5IMIA 2Q80A 1V4KA 5IL8A 3TFNA 3APZA 3QQVA 4DXJA 4FJQA 3LMDA 5B02A 1WL2A 2AETA 2RAHA 2AEKA 3EFQA 2H8OA 5HN8A 1HXGA 3KROB 5B0KA 3LK5A 2E93A 5DW7A 4H5DF 2ZY1A 5AFXA 3BNYA 4RXAA 3VJBA 4P0XA 3ZOUA 3LGKA 3TFVA 2E90A 4EA2A 3V1XA 1KIYA 3EGTA 3WCLA 2F8CF 1WKZA 2AZKA 2EWGA 4RXEA 5JV2F 3WJKA 2P1CA 2AZLA 4KVWA 2J1PA 2PS7A 3WE9A 3QKCA 5ILJA 3ZCDA 4XQRF 4DEMF 1HX9A 1V4EA 3BNXA 2O1OA 2Q9ZA 1RTRA 5DIQF 3SAEA 4P0WA 4UMJA 4LLTA 5H9DA 4RYPA 2Z4XA 3LSNA 2PS4A 4GA3A 3KRFB 3WCIA 3DYFA 4KQUA 5IMPA 2E91A 4KVYA 5A0JA 4JXYA 4KQSA 1YYSA 3M02A 5DJPF 1WY0A 1YJ4A 3Q1OA 3KRCB 1UBVA 3W7FA 2FTZA 3N0GA 2E8WA 5ER8A 1KIZA 4LA6A 3LVSA 3Q2QA 2Q58A 2PS6A 3N1VF 1RQJA 1WMWA 2AZJA 1VG6A 3P41A 4EA0A
chains in the Genus database with same CATH topology
3WSAA 4H5EF 3ACYA 1YYTA 3PKOA 2ZEVA 5C05A 5IK9A 5IMNA 3AQ0A 1N21A 4LTZA 4K10A 4MC8A 4KKMA 1WL1A 3MAVA 3VJCA 1JFGA 3EZ3A 5JV1F 3SDTA 4MC3A 2F9KF 3PYBA 3SDUA 4GAXA 5B03A 2E8XA 4N9UA 1VG4A 3PYAA 2E94A 1YV5A 3UCAA 1N22A 1DI1A 5ILYA 4Q23A 3ZL6A 5DGNF 3RMGA 5HNAA 2E95A 5CG5A 3TC1A 2ONGA 2E92A 1YHLA 5IKHA 2F8ZF 4WK5A 4H5CF 3KRPB 4LFVF 3WCDA 5ILZA 3WCEA 2DH4A 2ONHA 3WEJA 3N45F 3WSBA 3N46F 5B01A 2ZCQA 2QISA 3KROA 4F6XA 5E8HA 3B7LA 4JYXA 4KVIA 3AE0A 5ILKA 5DZ2A 4E9UA 3LGZB 3OABB 1N1ZA 2Z7IA 2ZEUA 3S4JA 3TS7A 5B0JA 2PS8A 2AELA 4JZBA 1UBWA 1HXAA 3NRIA 3PDEA 4LFEA 3SDVA 3LDWA 1JFAA 3P8LA 3WEHA 1UBYA 4KK2A 3WEIA 3WCJA 5E8LA 4LZ3A 5EAUA 4JXNA 4NKFA 1V4HA 3N5HF 3WJNA 5AHUB 3NF2A 3N5JF 3KB9A 4LZ0A 5EASA 3ZMCA 3WEFA 4EA1A 4XQSF 3P5PA 5DGSF 1RQIA 1HM4A 3KRCA 3RBMA 3ZMBA 5KSXF 3WCGA 3ACXA 3VJDA 3AQCB 4P0VA 3OACA 3WCFA 4NFIF 4NFKF 5B0LA 1PS1A 5DHKA 5DJRF 3P8RA 4DHDA 2F94F 5HN7A 5IVGA 4LFGA 4LXWA 3N1WF 3G4DA 4GP2A 4LTVA 4HD1A 4JVJF 3V1VA 2J5CA 2Z50A 3ASXA 4LA5A 4DWBA 2Q9YA 2OGDA 4KPJA 4NG6A 2Z4VA 4ZQ8A 3DYHA 4L2XF 3KRAB 3RYEA 3LG5A 5B00A 4KVDA 1YHKA 1HM7A 3ACWA 3NPKA 4DI5A 4OKMA 2FORA 2J1OA 5IM1A 4PVYF 3VJAA 1N20A 3CP6A 5IL3A 1YHMA 5B0MA 4E1EA 2OPMA 5AYPA 3NPRA 3ICZA 4F6VA 3RYWA 5IKAA 4LPGF 3TFPA 3ICMA 2E4OA 4NFJF 4FP4A 2Z7HA 4LLSA 3WEKA 1WL3A 4JZXA 4DWGA 3LZ9A 4RXDA 3VJ8A 4LIXA 5DJVF 2Z4WA 1VG7A 2E8TA 3KRPA 2VF6A 3IBAA 3N3DA 4RNQA 3CC9A 3LOMA 1V4IA 3N3LF 4LUUA 3WCBA 4NKEA 3LJIA 1V4JA 3OYRA 1VG2A 1YQ7A 2ZCOA 2OPNA 5HN9A 5E8KA 4OGUA 1DGPA 3OABA 5DGMF 2E8UA 1VG3A 1N23A 2ZCSA 1YYRA 3LEEA 4LZCA 2F7MF 1HXCA 3G4FA 3WCCA 4KPDA 2Z4ZA 3AQBB 3KRFA 5JV0F 5ILDA 3M0GA 4LPHF 1YYUA 3WEGA 4OMHA 4QXSF 4OMGA 2PS5A 5EROA 5IK0A 3VJ9A 3N6KF 5IN8A 3IPIA 4XQTF 3ID0A 3WJOA 5DHIA 3V66A 3PH7A 5A0KA 3DYGA 3ADZA 4KUXA 3P5RA 3LLWA 3WCHA 2Z4YA 2I19A 3CKEA 4DZWA 2Z52A 4KWDA 3KBKA 4OKZA 2Z78A 4QPFA 5B0IA 3OACB 4KQ5A 5ILHA 5JA0F 5ILIA 3M01A 5ERNA 3S9VA 3SDQA 4MC0A 5EATA 3Q30A 1WL0A 4PVXF 5I1UA 2F92F 4LOBA 3Q2ZA 1ZW5A 3N0FA 3WCMA 4N1ZF 1YYQA 3WC9A 4GP1A 3M00A 1EZFA 3VJEA 1N1BA 1N24A 3M9UA 1UBXA 4NUAA 1FPSA 3KRAA 4RXCA 4KFAA 2OA6A 2ZCRA 3MZVA 3WCAA 3SDRA 2F89F 5A0IA 5AELA 3ICKA 5IK6A 5CG6A 2E8VA 4F62A 3ICNA 5ERMA 5JUZF 4E9ZA 3N49F 5IMIA 2Q80A 1V4KA 5IL8A 3TFNA 3APZA 3QQVA 4DXJA 4FJQA 3LMDA 5B02A 1WL2A 2AETA 2RAHA 2AEKA 3EFQA 2H8OA 5HN8A 1HXGA 3KROB 5B0KA 3LK5A 2E93A 5DW7A 4H5DF 2ZY1A 5AFXA 3BNYA 4RXAA 3VJBA 4P0XA 3ZOUA 3LGKA 3TFVA 2E90A 4EA2A 3V1XA 1KIYA 3EGTA 3WCLA 2F8CF 1WKZA 2AZKA 2EWGA 4RXEA 5JV2F 3WJKA 2P1CA 2AZLA 4KVWA 2J1PA 2PS7A 3WE9A 3QKCA 5ILJA 3ZCDA 4XQRF 4DEMF 1HX9A 1V4EA 3BNXA 2O1OA 2Q9ZA 1RTRA 5DIQF 3SAEA 4P0WA 4UMJA 4LLTA 5H9DA 4RYPA 2Z4XA 3LSNA 2PS4A 4GA3A 3KRFB 3WCIA 3DYFA 4KQUA 5IMPA 2E91A 4KVYA 5A0JA 4JXYA 4KQSA 1YYSA 3M02A 5DJPF 1WY0A 1YJ4A 3Q1OA 3KRCB 1UBVA 3W7FA 2FTZA 3N0GA 2E8WA 5ER8A 1KIZA 4LA6A 3LVSA 3Q2QA 2Q58A 2PS6A 3N1VF 1RQJA 1WMWA 2AZJA 1VG6A 3P41A 4EA0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3WSA A;  4H5E F;  3ACY A;  1YYT A;  3PKO A;  2ZEV A;  5C05 A;  5IK9 A;  5IMN A;  3AQ0 A;  1N21 A;  4LTZ A;  4K10 A;  4MC8 A;  4KKM A;  1WL1 A;  3MAV A;  3VJC A;  1JFG A;  3EZ3 A;  5JV1 F;  3SDT A;  4MC3 A;  2F9K F;  3PYB A;  3SDU A;  4GAX A;  5B03 A;  2E8X A;  4N9U A;  1VG4 A;  3PYA A;  2E94 A;  1YV5 A;  3UCA A;  1N22 A;  1DI1 A;  5ILY A;  4Q23 A;  3ZL6 A;  5DGN F;  3RMG A;  5HNA A;  2E95 A;  5CG5 A;  3TC1 A;  2ONG A;  2E92 A;  1YHL A;  5IKH A;  2F8Z F;  4WK5 A;  4H5C F;  3KRP B;  4LFV F;  3WCD A;  5ILZ A;  3WCE A;  2DH4 A;  2ONH A;  3WEJ A;  3N45 F;  3WSB A;  3N46 F;  5B01 A;  2ZCQ A;  2QIS A;  3KRO A;  4F6X A;  5E8H A;  3B7L A;  4JYX A;  4KVI A;  3AE0 A;  5ILK A;  5DZ2 A;  4E9U A;  3LGZ B;  3OAB B;  1N1Z A;  2Z7I A;  2ZEU A;  3S4J A;  3TS7 A;  5B0J A;  2PS8 A;  2AEL A;  4JZB A;  1UBW A;  1HXA A;  3NRI A;  3PDE A;  4LFE A;  3SDV A;  3LDW A;  1JFA A;  3P8L A;  3WEH A;  1UBY A;  4KK2 A;  3WEI A;  3WCJ A;  5E8L A;  4LZ3 A;  5EAU A;  4JXN A;  4NKF A;  1V4H A;  3N5H F;  3WJN A;  5AHU B;  3NF2 A;  3N5J F;  3KB9 A;  4LZ0 A;  5EAS A;  3ZMC A;  3WEF A;  4EA1 A;  4XQS F;  3P5P A;  5DGS F;  1RQI A;  1HM4 A;  3KRC A;  3RBM A;  3ZMB A;  5KSX F;  3WCG A;  3ACX A;  3VJD A;  3AQC B;  4P0V A;  3OAC A;  3WCF A;  4NFI F;  4NFK F;  5B0L A;  1PS1 A;  5DHK A;  5DJR F;  3P8R A;  4DHD A;  2F94 F;  5HN7 A;  5IVG A;  4LFG A;  4LXW A;  3N1W F;  3G4D A;  4GP2 A;  4LTV A;  4HD1 A;  4JVJ F;  3V1V A;  2J5C A;  2Z50 A;  3ASX A;  4LA5 A;  4DWB A;  2Q9Y A;  2OGD A;  4KPJ A;  4NG6 A;  2Z4V A;  4ZQ8 A;  3DYH A;  4L2X F;  3KRA B;  3RYE A;  3LG5 A;  5B00 A;  4KVD A;  1YHK A;  1HM7 A;  3ACW A;  3NPK A;  4DI5 A;  4OKM A;  2FOR A;  2J1O A;  5IM1 A;  4PVY F;  3VJA A;  1N20 A;  3CP6 A;  5IL3 A;  1YHM A;  5B0M A;  4E1E A;  2OPM A;  5AYP A;  3NPR A;  3ICZ A;  4F6V A;  3RYW A;  5IKA A;  4LPG F;  3TFP A;  3ICM A;  2E4O A;  4NFJ F;  4FP4 A;  2Z7H A;  4LLS A;  3WEK A;  1WL3 A;  4JZX A;  4DWG A;  3LZ9 A;  4RXD A;  3VJ8 A;  4LIX A;  5DJV F;  2Z4W A;  1VG7 A;  2E8T A;  3KRP A;  2VF6 A;  3IBA A;  3N3D A;  4RNQ A;  3CC9 A;  3LOM A;  1V4I A;  3N3L F;  4LUU A;  3WCB A;  4NKE A;  3LJI A;  1V4J A;  3OYR A;  1VG2 A;  1YQ7 A;  2ZCO A;  2OPN A;  5HN9 A;  5E8K A;  4OGU A;  1DGP A;  3OAB A;  5DGM F;  2E8U A;  1VG3 A;  1N23 A;  2ZCS A;  1YYR A;  3LEE A;  4LZC A;  2F7M F;  1HXC A;  3G4F A;  3WCC A;  4KPD A;  2Z4Z A;  3AQB B;  3KRF A;  5JV0 F;  5ILD A;  3M0G A;  4LPH F;  1YYU A;  3WEG A;  4OMH A;  4QXS F;  4OMG A;  2PS5 A;  5ERO A;  5IK0 A;  3VJ9 A;  3N6K F;  5IN8 A;  3IPI A;  4XQT F;  3ID0 A;  3WJO A;  5DHI A;  3V66 A;  3PH7 A;  5A0K A;  3DYG A;  3ADZ A;  4KUX A;  3P5R A;  3LLW A;  3WCH A;  2Z4Y A;  2I19 A;  3CKE A;  4DZW A;  2Z52 A;  4KWD A;  3KBK A;  4OKZ A;  2Z78 A;  4QPF A;  5B0I A;  3OAC B;  4KQ5 A;  5ILH A;  5JA0 F;  5ILI A;  3M01 A;  5ERN A;  3S9V A;  3SDQ A;  4MC0 A;  5EAT A;  3Q30 A;  1WL0 A;  4PVX F;  5I1U A;  2F92 F;  4LOB A;  3Q2Z A;  1ZW5 A;  3N0F A;  3WCM A;  4N1Z F;  1YYQ A;  3WC9 A;  4GP1 A;  3M00 A;  1EZF A;  3VJE A;  1N1B A;  1N24 A;  3M9U A;  1UBX A;  4NUA A;  1FPS A;  3KRA A;  4RXC A;  4KFA A;  2OA6 A;  2ZCR A;  3MZV A;  3WCA A;  3SDR A;  2F89 F;  5A0I A;  5AEL A;  3ICK A;  5IK6 A;  5CG6 A;  2E8V A;  4F62 A;  3ICN A;  5ERM A;  5JUZ F;  4E9Z A;  3N49 F;  5IMI A;  2Q80 A;  1V4K A;  5IL8 A;  3TFN A;  3APZ A;  3QQV A;  4DXJ A;  4FJQ A;  3LMD A;  5B02 A;  1WL2 A;  2AET A;  2RAH A;  2AEK A;  3EFQ A;  2H8O A;  5HN8 A;  1HXG A;  3KRO B;  5B0K A;  3LK5 A;  2E93 A;  5DW7 A;  4H5D F;  2ZY1 A;  5AFX A;  3BNY A;  4RXA A;  3VJB A;  4P0X A;  3ZOU A;  3LGK A;  3TFV A;  2E90 A;  4EA2 A;  3V1X A;  1KIY A;  3EGT A;  3WCL A;  2F8C F;  1WKZ A;  2AZK A;  2EWG A;  4RXE A;  5JV2 F;  3WJK A;  2P1C A;  2AZL A;  4KVW A;  2J1P A;  2PS7 A;  3WE9 A;  3QKC A;  5ILJ A;  3ZCD A;  4XQR F;  4DEM F;  1HX9 A;  1V4E A;  3BNX A;  2O1O A;  2Q9Z A;  1RTR A;  5DIQ F;  3SAE A;  4P0W A;  4UMJ A;  4LLT A;  5H9D A;  4RYP A;  2Z4X A;  3LSN A;  2PS4 A;  4GA3 A;  3KRF B;  3WCI A;  3DYF A;  4KQU A;  5IMP A;  2E91 A;  4KVY A;  5A0J A;  4JXY A;  4KQS A;  1YYS A;  3M02 A;  5DJP F;  1WY0 A;  1YJ4 A;  3Q1O A;  3KRC B;  1UBV A;  3W7F A;  2FTZ A;  3N0G A;  2E8W A;  5ER8 A;  1KIZ A;  4LA6 A;  3LVS A;  3Q2Q A;  2Q58 A;  2PS6 A;  3N1V F;  1RQJ A;  1WMW A;  2AZJ A;  1VG6 A;  3P41 A;  4EA0 A; 
#chains in the Genus database with same CATH topology
 3WSA A;  4H5E F;  3ACY A;  1YYT A;  3PKO A;  2ZEV A;  5C05 A;  5IK9 A;  5IMN A;  3AQ0 A;  1N21 A;  4LTZ A;  4K10 A;  4MC8 A;  4KKM A;  1WL1 A;  3MAV A;  3VJC A;  1JFG A;  3EZ3 A;  5JV1 F;  3SDT A;  4MC3 A;  2F9K F;  3PYB A;  3SDU A;  4GAX A;  5B03 A;  2E8X A;  4N9U A;  1VG4 A;  3PYA A;  2E94 A;  1YV5 A;  3UCA A;  1N22 A;  1DI1 A;  5ILY A;  4Q23 A;  3ZL6 A;  5DGN F;  3RMG A;  5HNA A;  2E95 A;  5CG5 A;  3TC1 A;  2ONG A;  2E92 A;  1YHL A;  5IKH A;  2F8Z F;  4WK5 A;  4H5C F;  3KRP B;  4LFV F;  3WCD A;  5ILZ A;  3WCE A;  2DH4 A;  2ONH A;  3WEJ A;  3N45 F;  3WSB A;  3N46 F;  5B01 A;  2ZCQ A;  2QIS A;  3KRO A;  4F6X A;  5E8H A;  3B7L A;  4JYX A;  4KVI A;  3AE0 A;  5ILK A;  5DZ2 A;  4E9U A;  3LGZ B;  3OAB B;  1N1Z A;  2Z7I A;  2ZEU A;  3S4J A;  3TS7 A;  5B0J A;  2PS8 A;  2AEL A;  4JZB A;  1UBW A;  1HXA A;  3NRI A;  3PDE A;  4LFE A;  3SDV A;  3LDW A;  1JFA A;  3P8L A;  3WEH A;  1UBY A;  4KK2 A;  3WEI A;  3WCJ A;  5E8L A;  4LZ3 A;  5EAU A;  4JXN A;  4NKF A;  1V4H A;  3N5H F;  3WJN A;  5AHU B;  3NF2 A;  3N5J F;  3KB9 A;  4LZ0 A;  5EAS A;  3ZMC A;  3WEF A;  4EA1 A;  4XQS F;  3P5P A;  5DGS F;  1RQI A;  1HM4 A;  3KRC A;  3RBM A;  3ZMB A;  5KSX F;  3WCG A;  3ACX A;  3VJD A;  3AQC B;  4P0V A;  3OAC A;  3WCF A;  4NFI F;  4NFK F;  5B0L A;  1PS1 A;  5DHK A;  5DJR F;  3P8R A;  4DHD A;  2F94 F;  5HN7 A;  5IVG A;  4LFG A;  4LXW A;  3N1W F;  3G4D A;  4GP2 A;  4LTV A;  4HD1 A;  4JVJ F;  3V1V A;  2J5C A;  2Z50 A;  3ASX A;  4LA5 A;  4DWB A;  2Q9Y A;  2OGD A;  4KPJ A;  4NG6 A;  2Z4V A;  4ZQ8 A;  3DYH A;  4L2X F;  3KRA B;  3RYE A;  3LG5 A;  5B00 A;  4KVD A;  1YHK A;  1HM7 A;  3ACW A;  3NPK A;  4DI5 A;  4OKM A;  2FOR A;  2J1O A;  5IM1 A;  4PVY F;  3VJA A;  1N20 A;  3CP6 A;  5IL3 A;  1YHM A;  5B0M A;  4E1E A;  2OPM A;  5AYP A;  3NPR A;  3ICZ A;  4F6V A;  3RYW A;  5IKA A;  4LPG F;  3TFP A;  3ICM A;  2E4O A;  4NFJ F;  4FP4 A;  2Z7H A;  4LLS A;  3WEK A;  1WL3 A;  4JZX A;  4DWG A;  3LZ9 A;  4RXD A;  3VJ8 A;  4LIX A;  5DJV F;  2Z4W A;  1VG7 A;  2E8T A;  3KRP A;  2VF6 A;  3IBA A;  3N3D A;  4RNQ A;  3CC9 A;  3LOM A;  1V4I A;  3N3L F;  4LUU A;  3WCB A;  4NKE A;  3LJI A;  1V4J A;  3OYR A;  1VG2 A;  1YQ7 A;  2ZCO A;  2OPN A;  5HN9 A;  5E8K A;  4OGU A;  1DGP A;  3OAB A;  5DGM F;  2E8U A;  1VG3 A;  1N23 A;  2ZCS A;  1YYR A;  3LEE A;  4LZC A;  2F7M F;  1HXC A;  3G4F A;  3WCC A;  4KPD A;  2Z4Z A;  3AQB B;  3KRF A;  5JV0 F;  5ILD A;  3M0G A;  4LPH F;  1YYU A;  3WEG A;  4OMH A;  4QXS F;  4OMG A;  2PS5 A;  5ERO A;  5IK0 A;  3VJ9 A;  3N6K F;  5IN8 A;  3IPI A;  4XQT F;  3ID0 A;  3WJO A;  5DHI A;  3V66 A;  3PH7 A;  5A0K A;  3DYG A;  3ADZ A;  4KUX A;  3P5R A;  3LLW A;  3WCH A;  2Z4Y A;  2I19 A;  3CKE A;  4DZW A;  2Z52 A;  4KWD A;  3KBK A;  4OKZ A;  2Z78 A;  4QPF A;  5B0I A;  3OAC B;  4KQ5 A;  5ILH A;  5JA0 F;  5ILI A;  3M01 A;  5ERN A;  3S9V A;  3SDQ A;  4MC0 A;  5EAT A;  3Q30 A;  1WL0 A;  4PVX F;  5I1U A;  2F92 F;  4LOB A;  3Q2Z A;  1ZW5 A;  3N0F A;  3WCM A;  4N1Z F;  1YYQ A;  3WC9 A;  4GP1 A;  3M00 A;  1EZF A;  3VJE A;  1N1B A;  1N24 A;  3M9U A;  1UBX A;  4NUA A;  1FPS A;  3KRA A;  4RXC A;  4KFA A;  2OA6 A;  2ZCR A;  3MZV A;  3WCA A;  3SDR A;  2F89 F;  5A0I A;  5AEL A;  3ICK A;  5IK6 A;  5CG6 A;  2E8V A;  4F62 A;  3ICN A;  5ERM A;  5JUZ F;  4E9Z A;  3N49 F;  5IMI A;  2Q80 A;  1V4K A;  5IL8 A;  3TFN A;  3APZ A;  3QQV A;  4DXJ A;  4FJQ A;  3LMD A;  5B02 A;  1WL2 A;  2AET A;  2RAH A;  2AEK A;  3EFQ A;  2H8O A;  5HN8 A;  1HXG A;  3KRO B;  5B0K A;  3LK5 A;  2E93 A;  5DW7 A;  4H5D F;  2ZY1 A;  5AFX A;  3BNY A;  4RXA A;  3VJB A;  4P0X A;  3ZOU A;  3LGK A;  3TFV A;  2E90 A;  4EA2 A;  3V1X A;  1KIY A;  3EGT A;  3WCL A;  2F8C F;  1WKZ A;  2AZK A;  2EWG A;  4RXE A;  5JV2 F;  3WJK A;  2P1C A;  2AZL A;  4KVW A;  2J1P A;  2PS7 A;  3WE9 A;  3QKC A;  5ILJ A;  3ZCD A;  4XQR F;  4DEM F;  1HX9 A;  1V4E A;  3BNX A;  2O1O A;  2Q9Z A;  1RTR A;  5DIQ F;  3SAE A;  4P0W A;  4UMJ A;  4LLT A;  5H9D A;  4RYP A;  2Z4X A;  3LSN A;  2PS4 A;  4GA3 A;  3KRF B;  3WCI A;  3DYF A;  4KQU A;  5IMP A;  2E91 A;  4KVY A;  5A0J A;  4JXY A;  4KQS A;  1YYS A;  3M02 A;  5DJP F;  1WY0 A;  1YJ4 A;  3Q1O A;  3KRC B;  1UBV A;  3W7F A;  2FTZ A;  3N0G A;  2E8W A;  5ER8 A;  1KIZ A;  4LA6 A;  3LVS A;  3Q2Q A;  2Q58 A;  2PS6 A;  3N1V F;  1RQJ A;  1WMW A;  2AZJ A;  1VG6 A;  3P41 A;  4EA0 A; 
#chains in the Genus database with same CATH homology
 3WSA A;  4H5E F;  3ACY A;  1YYT A;  3PKO A;  2ZEV A;  5C05 A;  5IK9 A;  5IMN A;  3AQ0 A;  1N21 A;  4LTZ A;  4K10 A;  4MC8 A;  4KKM A;  1WL1 A;  3MAV A;  3VJC A;  1JFG A;  3EZ3 A;  5JV1 F;  3SDT A;  4MC3 A;  2F9K F;  3PYB A;  3SDU A;  4GAX A;  5B03 A;  2E8X A;  4N9U A;  1VG4 A;  3PYA A;  2E94 A;  1YV5 A;  3UCA A;  1N22 A;  1DI1 A;  5ILY A;  4Q23 A;  3ZL6 A;  5DGN F;  3RMG A;  5HNA A;  2E95 A;  5CG5 A;  3TC1 A;  2ONG A;  2E92 A;  1YHL A;  5IKH A;  2F8Z F;  4WK5 A;  4H5C F;  3KRP B;  4LFV F;  3WCD A;  5ILZ A;  3WCE A;  2DH4 A;  2ONH A;  3WEJ A;  3N45 F;  3WSB A;  3N46 F;  5B01 A;  2ZCQ A;  2QIS A;  3KRO A;  4F6X A;  5E8H A;  3B7L A;  4JYX A;  4KVI A;  3AE0 A;  5ILK A;  5DZ2 A;  4E9U A;  3LGZ B;  3OAB B;  1N1Z A;  2Z7I A;  2ZEU A;  3S4J A;  3TS7 A;  5B0J A;  2PS8 A;  2AEL A;  4JZB A;  1UBW A;  1HXA A;  3NRI A;  3PDE A;  4LFE A;  3SDV A;  3LDW A;  1JFA A;  3P8L A;  3WEH A;  1UBY A;  4KK2 A;  3WEI A;  3WCJ A;  5E8L A;  4LZ3 A;  5EAU A;  4JXN A;  4NKF A;  1V4H A;  3N5H F;  3WJN A;  5AHU B;  3NF2 A;  3N5J F;  3KB9 A;  4LZ0 A;  5EAS A;  3ZMC A;  3WEF A;  4EA1 A;  4XQS F;  3P5P A;  5DGS F;  1RQI A;  1HM4 A;  3KRC A;  3RBM A;  3ZMB A;  5KSX F;  3WCG A;  3ACX A;  3VJD A;  3AQC B;  4P0V A;  3OAC A;  3WCF A;  4NFI F;  4NFK F;  5B0L A;  1PS1 A;  5DHK A;  5DJR F;  3P8R A;  4DHD A;  2F94 F;  5HN7 A;  5IVG A;  4LFG A;  4LXW A;  3N1W F;  3G4D A;  4GP2 A;  4LTV A;  4HD1 A;  4JVJ F;  3V1V A;  2J5C A;  2Z50 A;  3ASX A;  4LA5 A;  4DWB A;  2Q9Y A;  2OGD A;  4KPJ A;  4NG6 A;  2Z4V A;  4ZQ8 A;  3DYH A;  4L2X F;  3KRA B;  3RYE A;  3LG5 A;  5B00 A;  4KVD A;  1YHK A;  1HM7 A;  3ACW A;  3NPK A;  4DI5 A;  4OKM A;  2FOR A;  2J1O A;  5IM1 A;  4PVY F;  3VJA A;  1N20 A;  3CP6 A;  5IL3 A;  1YHM A;  5B0M A;  4E1E A;  2OPM A;  5AYP A;  3NPR A;  3ICZ A;  4F6V A;  3RYW A;  5IKA A;  4LPG F;  3TFP A;  3ICM A;  2E4O A;  4NFJ F;  4FP4 A;  2Z7H A;  4LLS A;  3WEK A;  1WL3 A;  4JZX A;  4DWG A;  3LZ9 A;  4RXD A;  3VJ8 A;  4LIX A;  5DJV F;  2Z4W A;  1VG7 A;  2E8T A;  3KRP A;  2VF6 A;  3IBA A;  3N3D A;  4RNQ A;  3CC9 A;  3LOM A;  1V4I A;  3N3L F;  4LUU A;  3WCB A;  4NKE A;  3LJI A;  1V4J A;  3OYR A;  1VG2 A;  1YQ7 A;  2ZCO A;  2OPN A;  5HN9 A;  5E8K A;  4OGU A;  1DGP A;  3OAB A;  5DGM F;  2E8U A;  1VG3 A;  1N23 A;  2ZCS A;  1YYR A;  3LEE A;  4LZC A;  2F7M F;  1HXC A;  3G4F A;  3WCC A;  4KPD A;  2Z4Z A;  3AQB B;  3KRF A;  5JV0 F;  5ILD A;  3M0G A;  4LPH F;  1YYU A;  3WEG A;  4OMH A;  4QXS F;  4OMG A;  2PS5 A;  5ERO A;  5IK0 A;  3VJ9 A;  3N6K F;  5IN8 A;  3IPI A;  4XQT F;  3ID0 A;  3WJO A;  5DHI A;  3V66 A;  3PH7 A;  5A0K A;  3DYG A;  3ADZ A;  4KUX A;  3P5R A;  3LLW A;  3WCH A;  2Z4Y A;  2I19 A;  3CKE A;  4DZW A;  2Z52 A;  4KWD A;  3KBK A;  4OKZ A;  2Z78 A;  4QPF A;  5B0I A;  3OAC B;  4KQ5 A;  5ILH A;  5JA0 F;  5ILI A;  3M01 A;  5ERN A;  3S9V A;  3SDQ A;  4MC0 A;  5EAT A;  3Q30 A;  1WL0 A;  4PVX F;  5I1U A;  2F92 F;  4LOB A;  3Q2Z A;  1ZW5 A;  3N0F A;  3WCM A;  4N1Z F;  1YYQ A;  3WC9 A;  4GP1 A;  3M00 A;  1EZF A;  3VJE A;  1N1B A;  1N24 A;  3M9U A;  1UBX A;  4NUA A;  1FPS A;  3KRA A;  4RXC A;  4KFA A;  2OA6 A;  2ZCR A;  3MZV A;  3WCA A;  3SDR A;  2F89 F;  5A0I A;  5AEL A;  3ICK A;  5IK6 A;  5CG6 A;  2E8V A;  4F62 A;  3ICN A;  5ERM A;  5JUZ F;  4E9Z A;  3N49 F;  5IMI A;  2Q80 A;  1V4K A;  5IL8 A;  3TFN A;  3APZ A;  3QQV A;  4DXJ A;  4FJQ A;  3LMD A;  5B02 A;  1WL2 A;  2AET A;  2RAH A;  2AEK A;  3EFQ A;  2H8O A;  5HN8 A;  1HXG A;  3KRO B;  5B0K A;  3LK5 A;  2E93 A;  5DW7 A;  4H5D F;  2ZY1 A;  5AFX A;  3BNY A;  4RXA A;  3VJB A;  4P0X A;  3ZOU A;  3LGK A;  3TFV A;  2E90 A;  4EA2 A;  3V1X A;  1KIY A;  3EGT A;  3WCL A;  2F8C F;  1WKZ A;  2AZK A;  2EWG A;  4RXE A;  5JV2 F;  3WJK A;  2P1C A;  2AZL A;  4KVW A;  2J1P A;  2PS7 A;  3WE9 A;  3QKC A;  5ILJ A;  3ZCD A;  4XQR F;  4DEM F;  1HX9 A;  1V4E A;  3BNX A;  2O1O A;  2Q9Z A;  1RTR A;  5DIQ F;  3SAE A;  4P0W A;  4UMJ A;  4LLT A;  5H9D A;  4RYP A;  2Z4X A;  3LSN A;  2PS4 A;  4GA3 A;  3KRF B;  3WCI A;  3DYF A;  4KQU A;  5IMP A;  2E91 A;  4KVY A;  5A0J A;  4JXY A;  4KQS A;  1YYS A;  3M02 A;  5DJP F;  1WY0 A;  1YJ4 A;  3Q1O A;  3KRC B;  1UBV A;  3W7F A;  2FTZ A;  3N0G A;  2E8W A;  5ER8 A;  1KIZ A;  4LA6 A;  3LVS A;  3Q2Q A;  2Q58 A;  2PS6 A;  3N1V F;  1RQJ A;  1WMW A;  2AZJ A;  1VG6 A;  3P41 A;  4EA0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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